 | | DRUG: Dicyclomine hydrochloride | |
| Entry |
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| Name |
Dicyclomine hydrochloride (JAN/USP);
Dicycloverine hydrochloride;
Bentyl (TN);
Urispas (TN) |
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| Product |
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| Generic |
DICYCLOMINE (A-S Medication Solutions), DICYCLOMINE (Akorn), DICYCLOMINE (Hikma Pharmaceuticals USA), DICYCLOMINE (NCS HealthCare of KY), DICYCLOMINE (Quality Care Products), DICYCLOMINE (RedPharm Drug), DICYCLOMINE HCL (Nexus Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (ATLANTIC BIOLOGICALS CORP.), DICYCLOMINE HYDROCHLORIDE (Actavis Pharma), DICYCLOMINE HYDROCHLORIDE (Advagen Pharma Ltd.,), DICYCLOMINE HYDROCHLORIDE (American Health Packaging), DICYCLOMINE HYDROCHLORIDE (American Regent), DICYCLOMINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), DICYCLOMINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Bryant Ranch Prepack), DICYCLOMINE HYDROCHLORIDE (Cardinal Health 107), DICYCLOMINE HYDROCHLORIDE (Cardinal Health 107), DICYCLOMINE HYDROCHLORIDE (Chartwell RX), DICYCLOMINE HYDROCHLORIDE (Clinical Solutions Wholesale), DICYCLOMINE HYDROCHLORIDE (DIRECT RX), DICYCLOMINE HYDROCHLORIDE (DIRECT RX), DICYCLOMINE HYDROCHLORIDE (Denton Pharma), DICYCLOMINE HYDROCHLORIDE (Denton Pharma), DICYCLOMINE HYDROCHLORIDE (Denton Pharma), DICYCLOMINE HYDROCHLORIDE (Denton Pharma), DICYCLOMINE HYDROCHLORIDE (Direct_Rx), DICYCLOMINE HYDROCHLORIDE (Fosun Pharma USA), DICYCLOMINE HYDROCHLORIDE (Fresenius Kabi USA), DICYCLOMINE HYDROCHLORIDE (Gland Pharma Limited), DICYCLOMINE HYDROCHLORIDE (Golden State Medical Supply), DICYCLOMINE HYDROCHLORIDE (HF Acquisition Co LLC), DICYCLOMINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), DICYCLOMINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), DICYCLOMINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), DICYCLOMINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), DICYCLOMINE HYDROCHLORIDE (Lannett Company), DICYCLOMINE HYDROCHLORIDE (Major Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Mylan Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Novitium Pharma LLC), DICYCLOMINE HYDROCHLORIDE (NuCare Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (NuCare Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (NuCare Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Par Pharmaceutical), DICYCLOMINE HYDROCHLORIDE (Preferred Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Preferred Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Preferred Pharmaceuticals), DICYCLOMINE HYDROCHLORIDE (Proficient Rx LP), DICYCLOMINE HYDROCHLORIDE (Proficient Rx LP), DICYCLOMINE HYDROCHLORIDE (Proficient Rx LP), DICYCLOMINE HYDROCHLORIDE (Proficient Rx LP), DICYCLOMINE HYDROCHLORIDE (Quality Care Products), DICYCLOMINE HYDROCHLORIDE (REMEDYREPACK), DICYCLOMINE HYDROCHLORIDE (REMEDYREPACK), DICYCLOMINE HYDROCHLORIDE (REMEDYREPACK), DICYCLOMINE HYDROCHLORIDE (REMEDYREPACK), DICYCLOMINE HYDROCHLORIDE (RedPharm Drug), DICYCLOMINE HYDROCHLORIDE (RedPharm Drug), DICYCLOMINE HYDROCHLORIDE (RedPharm Drug), DICYCLOMINE HYDROCHLORIDE (St Mary's Medical Park Pharmacy) |
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| Formula |
C19H35NO2. HCl
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| Exact mass |
345.2435
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| Mol weight |
345.9476
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
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| Remark |
| Product (DG00032): | D00717<US> |
| Product (mixture): | D04364<JP> |
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| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
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| Disease |
Functional bowel/irritable bowel syndrome [DS: H01615] |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AA Synthetic anticholinergics, esters with tertiary amino group
A03AA07 Dicycloverine
D00717 Dicyclomine hydrochloride (JAN/USP) <US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Antispasmodics, Gastrointestinal
Dicyclomine
D00717 Dicyclomine hydrochloride (JAN/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
15 Stomach pain and cramp relievers
D00717 Dicyclomine hydrochloride (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Dicycloverine
D00717 Dicyclomine hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00032 Dicycloverine
D00717 Dicyclomine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM1
D00717 Dicyclomine hydrochloride (JAN/USP) <US>
CHRM2
D00717 Dicyclomine hydrochloride (JAN/USP) <US>
CHRM3
D00717 Dicyclomine hydrochloride (JAN/USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00032 Dicycloverine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 X Cl 19.4100 -24.2269
2 C7a C 22.9995 -21.0687
3 O7a O 21.8052 -20.2963
4 O6a O 22.9995 -22.4294
5 C1b C 20.6584 -21.0687
6 C1b C 19.4937 -20.3973
7 N1c N 18.3113 -21.0687
8 C1b C 17.1407 -20.3973
9 C1b C 18.3113 -22.4294
10 C1a C 15.9761 -21.0687
11 C1a C 17.1407 -23.0949
12 C1z C 24.2547 -20.3859
13 C1y C 25.4975 -21.1457
14 C1x C 25.4621 -22.5461
15 C1x C 26.6758 -23.2883
16 C1x C 27.9254 -22.6083
17 C1x C 27.9607 -21.2079
18 C1x C 26.7470 -20.4657
19 C1x C 25.5110 -19.7020
20 C1x C 25.5466 -18.2798
21 C1x C 24.3328 -17.5378
22 C1x C 23.0767 -18.2217
23 C1x C 23.0409 -19.6439
BOND 23
1 2 3 1
2 2 4 2
3 3 5 1
4 5 6 1
5 6 7 1
6 7 8 1
7 7 9 1
8 8 10 1
9 9 11 1
10 2 12 1
11 12 13 1
12 13 14 1
13 14 15 1
14 15 16 1
15 16 17 1
16 17 18 1
17 13 18 1
18 12 19 1
19 19 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 12 23 1
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