| Entry |
|
|---|
| Name |
Lisuride maleate (JAN) |
|---|
| Formula |
C20H26N4O. C4H4O4
|
|---|
| Exact mass |
454.2216
|
|---|
| Mol weight |
454.52
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
|
|---|
| Remark |
|
|---|
| Efficacy |
Antimigraine, Dopamine receptor agonist |
|---|
| Comment |
Ergot alkaloid
Prolactin inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G02 OTHER GYNECOLOGICALS
G02C OTHER GYNECOLOGICALS
G02CB Prolactine inhibitors
G02CB02 Lisuride
D01462 Lisuride maleate (JAN)
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CA Ergot alkaloids
N02CA07 Lisuride
D01462 Lisuride maleate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00453 Lisuride
D01462 Lisuride maleate
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00453 Lisuride
D01462 Lisuride maleate
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
DG00453 Lisuride
D01462 Lisuride maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01462 Lisuride maleate (JAN)
DRD3
D01462 Lisuride maleate (JAN)
DRD4
D01462 Lisuride maleate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00453 Lisuride
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00453 Lisuride
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
DG00453 Lisuride
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 33
1 C8x C 23.3538 -18.5435
2 C8x C 23.3538 -19.9101
3 C8x C 24.5401 -17.8602
4 C8y C 25.7194 -18.5435
5 C1x C 28.0806 -19.9202
6 C2y C 26.9060 -17.8653
7 C1y C 28.0807 -18.5564
8 N1y N 29.2665 -17.8845
9 C1y C 28.1031 -15.8306
10 C2x C 26.8470 -16.5022
11 C8y C 25.7136 -19.9101
12 C8y C 24.5368 -20.5875
13 N4x N 24.5351 -21.9921
14 C8x C 26.8873 -21.9484
15 C8y C 26.8889 -20.5905
16 N1b N 28.1142 -14.4640
17 C5a C 29.3033 -13.7905
18 N1c N 30.4810 -14.4833
19 C1b C 31.6703 -13.8098
20 C1a C 30.4445 -18.5776
21 C1b C 30.4699 -15.8500
22 C1x C 29.2808 -16.5235
23 C1a C 31.6477 -16.5428
24 C1a C 32.8481 -14.5029
25 O5a O 29.2995 -12.4100
26 C6a C 39.4265 -20.0084
27 C2b C 38.7455 -18.8337
28 O6a O 38.7517 -21.1893
29 O6a O 40.7887 -20.0020
30 C2b C 37.1147 -18.8398
31 C6a C 36.4399 -20.0207
32 O6a O 35.0776 -20.0207
33 O6a O 37.1272 -21.1955
BOND 35
1 10 6 2
2 4 11 1
3 15 5 1
4 5 7 1
5 6 4 1
6 11 12 2
7 12 13 1
8 14 15 2
9 15 11 1
10 13 14 1
11 1 2 2
12 9 16 1 #Down
13 2 12 1
14 19 24 1
15 16 17 1
16 4 3 2
17 3 1 1
18 17 18 1
19 18 19 1
20 6 7 1
21 8 20 1
22 7 8 1
23 18 21 1
24 8 22 1
25 22 9 1
26 21 23 1
27 9 10 1
28 17 25 2
29 26 27 1
30 26 28 1
31 26 29 2
32 27 30 2
33 30 31 1
34 31 32 1
35 31 33 2
|
|---|
