KEGG   DRUG: MebhydrolinHelp
Entry
D08161                      Drug                                   

Name
Mebhydrolin (INN);
Bexidal (TN)
Formula
C19H20N2
Exact mass
276.1626
Mol weight
276.3755
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Remark
ATC code: R06AX15
Chemical structure group: DG01113
Efficacy
Antiallergic, H1 receptor antagonist
Target
HRH1 [HSA:3269] [KO:K04149]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX15 Mebhydrolin
      D08161  Mebhydrolin (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Mebhydrolin
    D08161  Mebhydrolin (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    HRH1
     D08161  Mebhydrolin (INN)
BRITE hierarchy
Other DBs
CAS: 524-81-2
PubChem: 96024851
ChEMBL: CHEMBL1625607
LigandBox: D08161
NIKKAJI: J6.642G
LinkDB All DBs
KCF data Show

ATOM        21
            1   C8x C    20.4400  -16.4500
            2   C8x C    20.4400  -17.8500
            3   C8x C    21.6300  -18.5500
            4   C8x C    21.6300  -15.7500
            5   C8y C    22.8900  -16.4500
            6   C8y C    22.8900  -17.8500
            7   N4y N    24.2200  -18.3400
            8   C8y C    24.2200  -16.0300
            9   C8y C    24.9900  -17.2200
            10  C1x C    26.3900  -17.0800
            11  C1x C    27.0200  -15.7500
            12  N1y N    26.1800  -14.6300
            13  C1x C    24.7800  -14.7700
            14  C1a C    26.7400  -13.3700
            15  C1b C    24.2200  -19.7400
            16  C8y C    25.4100  -20.4400
            17  C8x C    25.4100  -21.8400
            18  C8x C    26.6700  -22.5400
            19  C8x C    27.8600  -21.8400
            20  C8x C    27.8600  -20.4400
            21  C8x C    26.6700  -19.7400
BOND        24
            1     5   6 1
            2     6   7 1
            3     7   9 1
            4     8   5 1
            5     3   6 2
            6    12  14 1
            7     5   4 2
            8     4   1 1
            9     1   2 2
            10    2   3 1
            11    8   9 2
            12    9  10 1
            13   10  11 1
            14   11  12 1
            15   12  13 1
            16   13   8 1
            17    7  15 1
            18   15  16 1
            19   16  17 2
            20   17  18 1
            21   18  19 2
            22   19  20 1
            23   20  21 2
            24   16  21 1

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