| Entry |
|
|---|
| Name |
Phendimetrazine hydrochloride;
Antapentan (TN) |
|---|
| Formula |
C12H17NO. HCl
|
|---|
| Exact mass |
227.1077
|
|---|
| Mol weight |
227.7304
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
|
|---|
| Remark |
| Product (DG01537): | D02080<US> |
|
|---|
| Efficacy |
Appetite suppressant (systemic), Stimulant (central) |
|---|
| Comment |
Morpholine derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01537 Phendimetrazine
D08348 Phendimetrazine hydrochloride
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
DG01537 Phendimetrazine
D08348 Phendimetrazine hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D08348 Phendimetrazine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01537 Phendimetrazine
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
DG01537 Phendimetrazine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 15
1 X Cl 27.3952 -18.9160
2 C8x C 17.3600 -17.0800
3 C8x C 17.3600 -18.4800
4 C8x C 18.5500 -19.1800
5 C8x C 19.7400 -18.4800
6 C8y C 19.7400 -17.0800
7 C8x C 18.5500 -16.3800
8 C1y C 21.0000 -16.3800
9 C1y C 22.1900 -17.0800
10 N1y N 23.3800 -16.3800
11 C1x C 23.3800 -14.9800
12 C1x C 22.1900 -14.2800
13 O2x O 21.0000 -14.9800
14 C1a C 24.6400 -17.0800
15 C1a C 22.1900 -18.4800
BOND 15
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 8 6 1 #Down
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 8 13 1
14 10 14 1
15 9 15 1 #Up
|
|---|
