KEGG   DRUG: PirenzepineHelp
Entry
D08389                      Drug                                   

Name
Pirenzepine (INN)
Formula
C19H21N5O2
Exact mass
351.1695
Mol weight
351.4023
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Same as: C07508
ATC code: A02BX03
Chemical structure group: DG00026
Product (DG00026): D05276<JP>
Efficacy
Antisecretory (gastric acid), Anti-ulcerative, Muscarinic acetylcholine receptor antagonist
Comment
Tricyclic compound
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion
Interaction
Drug interaction
Structure map
map07038  Antiulcer drugs
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A02 DRUGS FOR ACID RELATED DISORDERS
   A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
     A02BX03 Pirenzepine
      D08389  Pirenzepine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Pirenzepine
    D08389  Pirenzepine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D08389  Pirenzepine (INN)
BRITE hierarchy
Other DBs
CAS: 28797-61-7
PubChem: 96025075
ChEBI: 8247
ChEMBL: CHEMBL9967
DrugBank: DB00670
LigandBox: D08389
NIKKAJI: J20.030A
LinkDB All DBs
KCF data Show

ATOM        26
            1   C5x C    23.3800  -22.6800
            2   C8y C    22.5400  -21.6300
            3   C8y C    22.8900  -20.2300
            4   N1y N    24.1500  -19.6700
            5   N1x N    24.7800  -22.7500
            6   C8y C    25.4100  -20.3000
            7   C8y C    25.6900  -21.6300
            8   C8x C    21.9100  -19.2500
            9   C8x C    20.5100  -19.6700
            10  C8x C    20.2300  -21.0000
            11  C8x C    21.2100  -21.9800
            12  C8x C    27.0200  -22.1200
            13  C8x C    28.0700  -21.1400
            14  C8x C    27.7900  -19.8100
            15  N5x N    26.4600  -19.3200
            16  O5x O    22.7500  -23.9400
            17  C5a C    24.1500  -18.2700
            18  C1b C    25.4100  -17.5700
            19  O5a O    22.9600  -17.5700
            20  N1y N    25.4100  -16.1700
            21  C1x C    26.6000  -15.5400
            22  C1x C    26.6000  -14.1400
            23  N1y N    25.4100  -13.4400
            24  C1x C    24.2200  -14.0700
            25  C1x C    24.2200  -15.4700
            26  C1a C    25.4100  -11.9700
BOND        29
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    1  16 2
            19    4  17 1
            20   17  18 1
            21   17  19 2
            22   18  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   20  25 1
            29   23  26 1

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