| Entry |
|
|---|
| Name |
Tilisolol (INN) |
|---|
| Formula |
C17H24N2O3
|
|---|
| Exact mass |
304.1787
|
|---|
| Mol weight |
304.38
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-anginal, Antihypertensive, beta-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01322 Tilisolol
D08598 Tilisolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D08598 Tilisolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01322 Tilisolol
|
|---|
| Other DBs |
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|---|
| LinkDB |
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|---|
| KCF data |
ATOM 22
1 C8x C 17.9900 -19.6700
2 C8x C 17.9900 -18.2700
3 C8x C 19.1800 -17.5700
4 C8x C 19.1800 -20.3700
5 C8y C 20.3700 -19.6700
6 C8y C 20.3700 -18.2700
7 C8y C 21.6300 -17.5700
8 C8x C 22.8200 -18.2700
9 N4y N 22.8200 -19.6700
10 C8y C 21.6300 -20.3700
11 O5x O 21.6300 -21.7700
12 O2a O 21.6300 -16.1700
13 C1b C 22.8200 -15.4700
14 C1c C 24.0100 -16.1700
15 C1b C 25.2700 -15.4700
16 N1b N 26.4600 -16.1700
17 C1d C 27.6500 -15.5400
18 O1a O 24.0100 -17.5700
19 C1a C 27.6500 -14.1400
20 C1a C 28.9100 -16.2400
21 C1a C 28.9100 -14.8400
22 C1a C 24.0800 -20.3700
BOND 23
1 4 1 1
2 10 11 2
3 7 12 1
4 12 13 1
5 1 2 2
6 13 14 1
7 2 3 1
8 14 15 1
9 3 6 2
10 15 16 1
11 5 4 2
12 16 17 1
13 5 6 1
14 14 18 1
15 6 7 1
16 17 19 1
17 7 8 2
18 17 20 1
19 8 9 1
20 17 21 1
21 9 10 1
22 9 22 1
23 10 5 1
|
|---|
