| Entry |
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| Name |
Elexacaftor, ivacaftor and tezacaftor;
Trikafta (TN);
Kaftrio (TN) |
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| Product |
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| Component |
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| Remark |
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| Efficacy |
Cystic fibrosis treatment |
|---|
| Disease |
Cystic fibrosis (CFTR F508del mutation) [DS: H00218] |
|---|
| Target |
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| Pathway |
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| Metabolism |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R07 OTHER RESPIRATORY SYSTEM PRODUCTS
R07A OTHER RESPIRATORY SYSTEM PRODUCTS
R07AX Other respiratory system products
R07AX32 Ivacaftor, tezacaftor and elexacaftor
D11700 Elexacaftor, ivacaftor and tezacaftor <US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Cystic Fibrosis Agents
Conductance Regulator Potentiator
Elexacaftor/ Tezacaftor/ Ivacaftor
D11700 Elexacaftor, ivacaftor and tezacaftor
Target-based classification of drugs [BR:br08310]
Transporters
ABC transporters
ABCC subfamily
CFTR* [HSA_VAR:1080v1]
D11700 Elexacaftor, ivacaftor and tezacaftor <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D11700
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D11700
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D11700
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D11700
Pharmacogenomic biomarkers [br08341.html]
Germline mutations in genetic disorder treatments
D11700
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| Other DBs |
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| LinkDB |
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