KEGG   DRUG: Insulin icodec
Entry
D12358                      Drug                                   
Name
Insulin icodec (USAN/INN);
Insulin icodec (genetical recombination) (JAN);
Awiqli (TN)
Formula
C280H435N71O87S6
Exact mass
6376.0121
Mol weight
6380.28
Sequence
(A chain)
GIVEQCCTSI CSLEQLENYC N
(B chain)
FVNQHLCGSH LVEALHLVCG ERGFHYTPK
(Disulfide bridge: A6-A11, A7-B7, A20-B19)
  Type
Peptide
Class
Antidiabetic agent
 DG01636  Insulin preparation
  DG01797  Insulin analog, long-acting
Remark
Therapeutic category: 2492
ATC code: A10AE07
Product: D12358<JP>
Efficacy
Antidiabetic, Insulin receptor agonist
Comment
Insulin analog
Target
INSR (CD220) [HSA:3643] [KO:K04527]
  Pathway
hsa04910  Insulin signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10A INSULINS AND ANALOGUES
    A10AE Insulins and analogues for injection, long-acting
     A10AE07 Insulin icodec
      D12358  Insulin icodec (USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2492  Pancreatic hormones
     D12358  Insulin icodec (USAN/INN); Insulin icodec (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG01636  Insulin preparation
   DG01797  Insulin analog, long-acting
    D12358  Insulin icodec
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01636  Insulin preparation
   D12358  Insulin icodec
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   INSR family
    INSR (CD220)
     D12358  Insulin icodec (USAN/INN) <JP>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D12358
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D12358
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D12358
Other DBs
CAS: 1188379-43-2
PubChem: 497620771
LinkDB

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