KEGG   GLYCAN: G00062
Entry
G00062                      Glycan                                 
Name
Sialyl-3-paragloboside;
3'-LM1;
IV3-a-Neu5Ac-nLc4Cer;
snLc4Cer
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (Neu5Ac)1 (Cer)1
Mass
980.9 (Cer)
Structure
Remark
Same as: C04936
Reaction
R06026 R06032 R06075 R13169
Pathway
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map01100  Metabolic pathways
Network
nt06035  Blood group carbohydrate antigen biosynthesis
Enzyme
2.4.1.65        2.4.1.-         2.4.3.6         2.4.3.8
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP06 Acidic glycosphingolipids
   SP0601 Gangliosides
    G00062  Neu5Ac-alpha2->3Gal-beta1->4GlcNAc-beta1->3Gal-beta1->4Glc-beta1->1'Cer
Cancer-associated carbohydrates [br08441.html]
 Glycosphingolipid
  G00062
Reference
1  [PMID:2960671]
  Authors
Holmes EH, Hakomori S, Ostrander GK.
  Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 262:15649-58 (1987)
Reference
2  [PMID:15546874]
  Authors
Ideo H, Seko A, Yamashita K.
  Title
Galectin-4 binds to sulfated glycosphingolipids and carcinoembryonic antigen in patches on the cell surface of human colon adenocarcinoma cells.
  Journal
J Biol Chem 280:4730-7 (2005)
DOI:10.1074/jbc.M410362200
Other DBs
CCSD: 
GlyTouCan: G01767JJ
LIPIDMAPS: LMSP0601EF00
JCGGDB: JCGG-STR027108
GlycoEpitope: EP0076 EP0301 EP0304 EP0314
LinkDB
KCF data

NODE        6
            1   Cer        20     0
            2   Glc        13     0
            3   Gal         6     0
            4   GlcNAc     -2     0
            5   Gal       -10     0
            6   Neu5Ac    -18     0
EDGE        5
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:3  
            4     5:b1    4:4  
            5     6:a2    5:3

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