Granulibacter is a gram-negative acetic acid bacterium that is recently reported to be a human opportunistic pathogen. Granulibacter has been isolated from patients with chronic granulomatous disease, in which phagocytes are not able to produce bactericidal superoxide anions. Bacteremia has also been observed in a non-immunocompromised patient with a history of intravenous drug abuse.
Brite Infectious diseases [BR: br08401]
Infections caused by alpha proteobacteria
H01167 Granulibacter infection
CYBB (Chronic granulomatous disease) [HSA:
CYBA (Chronic granulomatous disease) [HSA:
NCF1 (Chronic granulomatous disease) [HSA:
Granulibacter bethesdensis [GN:
Chronic granulomatous disease is described in
Greenberg DE, Ding L, Zelazny AM, Stock F, Wong A, Anderson VL, Miller G, Kleiner DE, Tenorio AR, Brinster L, Dorward DW, Murray PR, Holland SM
A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease.
Greenberg DE, Porcella SF, Stock F, Wong A, Conville PS, Murray PR, Holland SM, Zelazny AM
Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae.
Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM.
Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.
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