KEGG   DISEASE: Granulibacter infection
Entry
H01167                      Disease                                
Name
Granulibacter infection
Description
Granulibacter is a gram-negative acetic acid bacterium that is recently reported to be a human opportunistic pathogen. Granulibacter has been isolated from patients with chronic granulomatous disease, in which phagocytes are not able to produce bactericidal superoxide anions. Bacteremia has also been observed in a non-immunocompromised patient with a history of intravenous drug abuse.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by alpha proteobacteria
   H01167  Granulibacter infection
Gene
CYBB (Chronic granulomatous disease) [HSA:1536] [KO:K21421]
CYBA (Chronic granulomatous disease) [HSA:1535] [KO:K08009]
NCF1 (Chronic granulomatous disease) [HSA:653361] [KO:K08011]
Pathogen
Granulibacter bethesdensis [GN:gbe]
Comment
Chronic granulomatous disease is described in H00098.
Reference
  Authors
Greenberg DE, Ding L, Zelazny AM, Stock F, Wong A, Anderson VL, Miller G, Kleiner DE, Tenorio AR, Brinster L, Dorward DW, Murray PR, Holland SM
  Title
A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease.
  Journal
PLoS Pathog 2:e28 (2006)
DOI:10.1371/journal.ppat.0020028
Reference
  Authors
Greenberg DE, Porcella SF, Stock F, Wong A, Conville PS, Murray PR, Holland SM, Zelazny AM
  Title
Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae.
  Journal
Int J Syst Evol Microbiol 56:2609-16 (2006)
DOI:10.1099/ijs.0.64412-0
Reference
  Authors
Greenberg DE, Porcella SF, Zelazny AM, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Barbian KD, Babar A, Dorward DW, Holland SM.
  Title
Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis.
  Journal
J Bacteriol 189:8727-36 (2007)
DOI:10.1128/JB.00793-07
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