Vitiligo is a common, multifactorial, polygenic disease in which autoimmune loss of melanocytes results in depigmented spots of skin, overlying hair, and mucous membranes. Some familial forms of vitiligo have recently been linked to polymorphisms in the innate immunity gene, NLRP1.
Category
Skin disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
14 Diseases of the skin
Skin disorders involving specific cutaneous structures
Disorders of the epidermis and epidermal appendages
Disorders of skin colour
ED63 Acquired hypomelanotic disorders
H01372 Vitiligo
Pathway-based classification of diseases [BR:br08402]
Immune system
nt06521 NLR signaling
H01372 Vitiligo