Entry Name malate dehydrogenase (oxaloacetate-decarboxylating);
Class Oxidoreductases;BRITE hierarchy
Sysname (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)
Reaction(IUBMB) (1) (S)-malate + NAD+ = pyruvate + CO2 + NADH [RN:
R00214 ];
(2) oxaloacetate = pyruvate + CO2 [RN:
R00217 ]
Reaction(KEGG) Substrate Product Comment Unlike EC
1.1.1.39 , malate dehydrogenase (decarboxylating), this enzyme can also decarboxylate oxaloacetate. cf. EC
1.1.1.40 , malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+).
History EC 1.1.1.38 created 1961
Pathway Orthology K00027 malate dehydrogenase (oxaloacetate-decarboxylating)
Genes PLEU : 114690185(Me2) 114691822
XLA : 108718602(me2.L) 398584(me2.S)
SANH : 107659429(me2) 107704075
SGH : 107557577 107594548(me2)
CAUA : 113067997 113073127 113073710
PFOR : 103135426 103135428
ONE : 115111253(me2) 115123084
PSPA : 121304278 121317816
ARUT : 117409546 117421420
VPO : Kpol_1018p36 Kpol_348p7
NCS : NCAS_0A04810(NCAS0A04810)
NDI : NDAI_0K01870(NDAI0K01870)
TPF : TPHA_0C04170(TPHA0C04170) TPHA_0G03490(TPHA0G03490)
TBL : TBLA_0B06420(TBLA0B06420) TBLA_0I01450(TBLA0I01450)
TDL : TDEL_0A03040(TDEL0A03040)
KAF : KAFR_0D03620(KAFR0D03620)
SPAA : SPAPADRAFT_63256(MAE1)
CAL : CAALFM_C601670WA(MAE1)
NTE : NEUTE1DRAFT150661(NEUTE1DRAFT_150661)
BFU : BCIN_05g08110(Bcmae1)
ANG : ANI_1_22104(An12g00160)
SPO : SPAC750.08c SPCC794.12c(mae2)
CGI : CGB_F1440C CGB_H3250W
PPL : POSPLDRAFT_87605 POSPLDRAFT_89079
TVS : TRAVEDRAFT_138083 TRAVEDRAFT_32715
DSQ : DICSQDRAFT_123782 DICSQDRAFT_77127
LBC : LACBIDRAFT_240874 LACBIDRAFT_255070 LACBIDRAFT_255095
SCM : SCHCODRAFT_62284 SCHCODRAFT_74986
ABP : AGABI1DRAFT52271(AGABI1DRAFT_52271)
ABV : AGABI2DRAFT62584(AGABI2DRAFT_62584)
EHI : EHI_044970(425.t00002) EHI_050330
EIV : EIN_393440 EIN_418120 EIN_498890
TBR : Tb11.02.3120 Tb11.02.3130
TCR : 505183.20 505183.30 508647.270 508647.280
LIF : LINJ_24_0780 LINJ_24_0790
ECOO : ECRM13514_1923(sfcA)
ECOH : ECRM13516_1835(sfcA)
ECW : EcE24377A_1661(sfcA)
EUN : UMNK88_1884(sfcA) UMNK88_pK8825
ECY : ECSE_1568 ECSE_P3-0045
EDJ : ECDH1ME8569_1422(maeA)
ECOI : ECOPMV1_01619(maeA)
ENL : A3UG_11690 A3UG_11930
ECLG : EC036_22330 EC036_22590
EAU : DI57_07105 DI57_07325
ERN : BFV67_11140 BFV67_11345
ECLS : LI67_013950 LI67_014225
ESH : C1N69_11590 C1N69_11855
EAS : Entas_2203 Entas_2268
ENX : NI40_011580 NI40_011775
ENF : AKI40_1018 AKI40_3141
LNI : CWR52_00425 CWR52_00705
KPE : KPK_1916 KPK_2508(sfcA)
KPK : A593_01480 A593_24100
KVD : KR75_22030 KR75_25190
KVQ : SP68_02785 SP68_05555
KOY : J415_13740 J415_17505
KOK : KONIH1_14205 KONIH1_18165
KQU : AVR78_18265 AVR78_20965
KLL : BJF97_14345 BJF97_18065
ROR : RORB6_02905 RORB6_06655
RON : TE10_13940 TE10_18375
RPLN : B1209_09345 B1209_13755
RAO : DSD31_09340 DSD31_13270
RTG : NCTC13098_02722(maeA_1) NCTC13098_03788(maeA_2) NCTC13098_04546(maeA_3)
REE : electrica_01869(maeA_1) electrica_02582(maeA_2)
CBRA : A6J81_04350 A6J81_22550
CYO : CD187_11805 CD187_12950
CPOT : FOB25_00695 FOB25_16600 FOB25_23340
CIF : AL515_12220 AL515_18305
CARS : E1B03_13375 E1B03_20825
CLAP : NCTC11466_02256(maeA)
PGE : LG71_13550 LG71_17140
ESC : Entcl_1687 Entcl_2342
KLE : AO703_10515 AO703_13535
KOR : AWR26_05955 AWR26_12860
KRD : A3780_11185 A3780_18055
KIE : NCTC12125_01309(maeA)
METY : MRY16398_28930(maeA) MRY16398_32670
KIN : AB182_12290 AB182_14450
PDZ : HHA33_15180 HHA33_17085
PSHI : SAMEA2665130_0738(maeA_1) SAMEA2665130_1323(maeA_2)
EBC : C2U52_23175 C2U52_25045
EBU : CUC76_01895 CUC76_24660
YAK : ACZ76_02000 ACZ76_05605
SMW : SMWW4_v1c15510(maeA)
SFJ : SAMEA4384070_1604(maeA)
SOF : NCTC11214_05364(maeA)
RAH : Rahaq_1422 Rahaq_5027
RACE : JHW33_01560 JHW33_24440
ROX : BV494_02440 BV494_22210
GQU : AWC35_04390 AWC35_14300
TPTY : NCTC11468_02425(maeA_1) NCTC11468_02426(maeA_2)
PALA : CO695_06610 CO695_18115
PHEI : NCTC12003_02850(maeA)
PRJ : NCTC6933_01216(maeA)
LRI : NCTC12151_02098(maeA)
AVT : NCTC3438_01175(maeA)
VFU : vfu_A01702 vfu_A02184
VAU : VANGNB10_cI1042c(sfcA)
VBR : A6E01_06835 A6E01_07225
VZI : G5S32_05800 G5S32_18220
PPR : PBPRA1997(STM1566) PBPRB0396(PLU1546) PBPRB1354(T1481)
PGB : H744_1c1254 H744_2c2134
PDS : CAY62_06925 CAY62_16750
PGH : FH974_07380 FH974_17345
PAEB : NCGM1900_2798(sfcA)
PVD : CFBP1590__3936(maeA)
PGG : FX982_00262 FX982_02661
PSYC : DABAL43B_1132(sfcA)
ALW : FOB21_00025(maeA) FOB21_09350(maeA)
SCAA : TUM17387_08920(maeA)
COLW : A3Q33_11875 A3Q33_19660
COLA : DBO93_08290 DBO93_15150
CBER : B5D82_11840 B5D82_17195 B5D82_18930
AMK : AMBLS11_02045 AMBLS11_04100
SALH : HMF8227_02180(sfcA)
AGZ : M0C34_05065 M0C34_19880
CBS : COXBURSA331_A1127(sfcA)
ASIP : AQUSIP_03210(maeA_1) AQUSIP_05420(maeA_2)
LPN : lpg0651 lpg1280(sfcA) lpg2971(maeA)
LPH : LPV_1393(sfcA) LPV_3358(sfcA)
LPO : LPO_1265(sfcA) LPO_3306(sfcA)
LPU : LPE509_00034 LPE509_01928
LPM : LP6_1263(sfcA1) LP6_3010(maeA)
LPF : lpl1243(sfcA) lpl2901
LPP : lpp1243(sfcA) lpp3043
LPC : LPC_0705(sfcA) LPC_3286(maeA)
LLO : LLO_0429(sfcA) LLO_0659 LLO_1147(sfcA)
LFA : LFA_1225(maeA) LFA_1712(sfcA)
LHA : LHA_1027(sfcA) LHA_1940(malS)
LOK : Loa_01979(mez3) Loa_02476(mez1)
LCD : clem_05465(maeA_1) clem_10030(maeA_2)
LSH : CAB17_06250 CAB17_07585 CAB17_09905
LLG : 44548918_00987(sfcA_1) 44548918_01884(sfcA_2)
LIB : E4T55_01640 E4T55_10280
LJR : NCTC11533_01170(sfcA_1) NCTC11533_02043(sfcA_2)
LCJ : NCTC11976_01010(sfcA_1) NCTC11976_01480(maeB_1) NCTC11976_01949(sfcA_2)
LWA : SAMEA4504053_1474(maeA_1) SAMEA4504053_3485(maeA_2)
LSS : NCTC12082_00258(maeA) NCTC12082_01266(sfcA)
LADL : NCTC12735_00694(maeA_1) NCTC12735_01145(maeA_2)
LANT : TUM19329_15920(sfcA) TUM19329_17930(maeA)
TMC : LMI_1354(malS) LMI_2782(sfcA)
AHA : AHA_1243 AHA_1278 AHA_3059
AHY : AHML_06570 AHML_06740 AHML_16495
AHD : AI20_04080 AI20_12830 AI20_13025
AHR : V428_06800 V428_06970 V428_17065
AHP : V429_06800 V429_06970 V429_17100
AHJ : V469_06195 V469_16380 V469_16550
AHH : RY45_06630 RY45_06845 RY45_15795
AHI : VU14_06360 VU14_16305 VU14_16475
AAJ : BOQ57_06035 BOQ57_06210 BOQ57_15680
ASA : ASA_1233(sfcA) ASA_1264(maeA)
AEO : O23A_p0391 O23A_p0429 O23A_p2351
AVR : B565_1082 B565_2933 B565_2964
AVO : AMS64_07200 AMS64_17425 AMS64_17575
AMED : B224_1218 B224_3918 B224_3977
ASR : WL1483_3413(maeA) WL1483_654(maeA) WL1483_720(maeA)
ADH : CK627_10470 CK627_19760 CK627_19955
ACAV : VI35_14515 VI35_15060
AEM : CK911_01910 CK911_10865 CK911_11430
AEA : C2U39_15150 C2U39_16105
ARV : C7N77_09545 C7N77_09725 C7N77_10320
AEL : NCTC12917_03003(maeA_1) NCTC12917_03112(maeA_2) NCTC12917_03150(maeA_3)
ASIM : FE240_11460 FE240_11765
AALL : I6G90_00215 I6G90_00355 I6G90_10030
AJD : I6H43_04565 I6H43_04705 I6H43_16750
ARIV : KYK33_06475 KYK33_14335
CDIZ : CEDIAZO_01161(maeA_1)
ECOR : SAMEA4412678_0880(maeA)
PLG : NCTC10937_01571(sfcA)
LMIR : NCTC12852_00092(maeA)
