KEGG   ORTHOLOGY: K00076
Entry
K00076                      KO                                     
Symbol
hdhA
Name
7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]
Pathway
map00121  Secondary bile acid biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00121 Secondary bile acid biosynthesis
    K00076  hdhA; 7-alpha-hydroxysteroid dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.159  7alpha-hydroxysteroid dehydrogenase
     K00076  hdhA; 7-alpha-hydroxysteroid dehydrogenase
Other DBs
COG: COG1028
GO: 0008709
Genes
ECO: b1619(hdhA)
ECJ: JW1611(hdhA)
ECD: ECDH10B_1752(hdhA)
EBW: BWG_1433(hdhA)
ECOK: ECMDS42_1289(hdhA)
ECE: Z2624(hdhA)
ECS: ECs_2327(hdhA)
ECF: ECH74115_2331
ETW: ECSP_2183(hdhA)
ELX: CDCO157_2160
EOI: ECO111_2088(hdhA)
EOJ: ECO26_2347(hdhA)
EOH: ECO103_1759(hdhA)
ECOO: ECRM13514_2111(hdhA)
ECOH: ECRM13516_2013(hdhA)
ESL: O3K_12140
ESO: O3O_13495
ESM: O3M_12105
ECK: EC55989_1786(hdhA)
ECG: E2348C_1704(hdhA)
EOK: G2583_2013(hdhA)
ELH: ETEC_1653
ECP: ECP_1563
ENA: ECNA114_1666(hdhA)
ECOS: EC958_1840(hdhA)
ECV: APECO1_702(hdhA)
ECY: ECSE_1740
ECR: ECIAI1_1670(hdhA)
ECQ: ECED1_1819(hdhA)
EUM: ECUMN_1909(hdhA)
ECT: ECIAI39_1439(hdhA)
EOC: CE10_1891(hdhA)
EBR: ECB_01588(hdhA)
EBL: ECD_01588(hdhA)
EBE: B21_01578(hdhA)
EBD: ECBD_2026
ECI: UTI89_C1807(hdhA)
ECZ: ECS88_1666(hdhA)
ECC: c2011(hdhA)
ELO: EC042_1787(hdhA)
ESE: ECSF_1480
EKF: KO11_14655(hdhA)
EAB: ECABU_c18710(hdhA)
EDJ: ECDH1ME8569_1562(hdhA)
ELW: ECW_m1785(hdhA)
ELL: WFL_08740(hdhA)
ELC: i14_1831(hdhA)
ELD: i02_1831(hdhA)
ELP: P12B_c1464(hdhA)
ELF: LF82_0973(hdhA)
ECOI: ECOPMV1_01714(hdhA)
ECOJ: P423_08660
ESZ: FEM44_23020(hdhA)
SFL: SF1644
SFN: SFy_2351
SFS: SFyv_2405
SFT: NCTC1_01782(hdhA)
SSN: SSON_1541(hdhA)
SBO: SBO_1517(hdhA)
SDY: SDY_1838(hdhA)
PSHI: SAMEA2665130_1873(hdhA)
ADP: NCTC12871_00061(hdhA)
PMEX: H4W19_17740(hdhA)
PPUT: L483_14070
PPUN: PP4_27250
PSA: PST_0160
PSIL: PMA3_11740
PTAE: NCTC10697_02058(hdhA)
PSYC: DABAL43B_2359(hdhA)
ACB: A1S_3474
ABOU: ACBO_29550(hdhA)
PHA: PSHAa2129(hdhA)
PTN: PTRA_a2582(hdhA) PTRA_b0693(hdhA)
PNG: PNIG_a2776(hdhA)
THIP: N838_00855(hdhA) N838_28820
TBOG: LT988_04030(hdhA)
OCE: GU3_12620
BXE: Bxe_C0288
BXB: DR64_8145
CTES: O987_07540
NET: Neut_1072
HPY: HP_1014
HPJ: jhp_0409
HPG: HPG27_414
HPL: HPB8_1130(hdhA)
HPZ: HPKB_0437
HPD: KHP_0420(hdhA)
HEY: MWE_0518
HPYR: K747_10870
HPYI: K750_03740
HPYU: K751_05290
HPYM: K749_03465
HEB: U063_1219
HEZ: U064_1223
HHE: HH_1627
HAC: Hac_1118(hdhA)
HMS: HMU14020
HCE: HCW_03695
HCM: HCD_06040
HCP: HCN_0775
HCL: NCTC13205_01179(fabL)
HSH: NHP194022_15110(hdhA)
WSU: WS2222
SUA: Saut_0922
SULC: CVO_05190
SULR: B649_07490
CJE: Cj0807
CJU: C8J_0758
CJI: CJSA_0763
CJM: CJM1_0784
CJS: CJS3_0855
CJEJ: N564_00786
CJEU: N565_00830
CJEN: N755_00827
CJEI: N135_00852
CJER: H730_04935
CJY: QZ67_00875(fabL)
CJQ: UC78_0770(fabL)
CJR: CJE0898
CFZ: CSG_12070
CLA: CLA_0625
CCQ: N149_0749
CCF: YSQ_05365
CCY: YSS_04040
CCOI: YSU_05020
CCOF: VC76_03920(fabL)
CCOO: ATE51_02030(fabL)
CIS: CINS_0600
CVO: CVOL_0619
CPEL: CPEL_0692
CGRA: CGRAC_1259
CURE: CUREO_0896
CHYO: CHH_0712
CSPF: CSF_1172
CCUN: CCUN_0804
CLX: CLAN_0896
CAVI: CAV_0650
CAMY: CSUIS_0947
COJ: CORN_0707
CGEO: CGEO_1020
CBLA: CBLAS_0865
CCOR: CCORG_0774
CARM: CARM_0690
CMUC: CMCT_0879
CSHO: CSHOW_0956
CINF: CINF_0722
SDL: Sdel_1059
SMUL: SMUL_1469
SHAL: SHALO_1439
SULJ: SJPD1_1446
ABU: Abu_0873
ABT: ABED_0825
ATP: ATR_1094
ACIB: ACBT_1565
ACRE: ACRYA_0869
APOC: APORC_1370
ATHR: ATH_1317
AELL: AELL_1015
AAQI: AAQM_0898
ASUI: ASUIS_1701
ACLO: ACLO_0968
ALK: ALEK_2461
AMYT: AMYT_1854
AMAR: AMRN_1809
ACAA: ACAN_1828
AMOL: AMOL_1854
APAI: APAC_1684
HBV: ABIV_1642
HEBR: AEBR_1977
PACO: AACT_1128
ARC: ABLL_1104
HYO: NNO_1099
SUN: SUN_0808
NIS: NIS_0698
NAM: NAMH_0962
KAI: K32_36820(hdhA)
BMEL: DK63_1019(hdhA) DK63_1020
BMEE: DK62_1927 DK62_1928(hdhA)
BABO: DK55_1585(hdhA) DK55_1586
BABR: DO74_303 DO74_304(hdhA)
BABT: DK49_1343(hdhA) DK49_1344
BABB: DK48_533 DK48_534(hdhA)
BABU: DK53_1569(hdhA) DK53_1570
BABS: DK51_1972 DK51_1973(hdhA)
BABC: DO78_1490(hdhA) DO78_1491
BSZ: DK67_709 DK67_710(hdhA)
BCAR: DK60_1627(hdhA) DK60_1628
BPP: BPI_I1675
BPV: DK65_1879 DK65_1880(hdhA)
META: Y590_18880
BVY: NCTC9239_00818(hdhA_3)
SIL: SPO3654
RUT: FIU92_02140(hdhA)
JAN: Jann_3883
RDE: RD1_1281
DSH: Dshi_0672
PGD: Gal_00421
OTM: OSB_28210(fabG_6)
LAQU: R2C4_14145
CID: P73_4196
MALG: MALG_02629
SINL: DSM14862_03001(fabG_9)
SPSE: SULPSESMR1_02760(fabG)
RMM: ROSMUCSMR3_02595(bacC)
RID: RIdsm_00133(ydaD_1)
ROH: FIU89_02020(fabG3)
MARU: FIU81_02760(hdhA)
ROT: FIV09_01880(fabG1)
MALU: KU6B_50150
RSP: RSP_0684
PDE: Pden_1754
PMAU: CP157_01787(fabG_2)
RSU: NHU_00279
RHC: RGUI_3217
LVS: LOKVESSMR4R_00749(bacC)
PAMO: BAR1_14065
PALW: PSAL_023510(bacC)
SFLA: SPHFLASMR4Y_02341(benD)
RMT: IAI58_21185(hdhA)
CSO: CLS_38520
MTU: Rv0927c
MTC: MT0954
MRA: MRA_0935
MTUR: CFBS_0975
MTD: UDA_0927c
MTUE: J114_04965
MTUL: TBHG_00912
MTUT: HKBT1_0975
MTUU: HKBT2_0976
MBB: BCG_0979c
MBT: JTY_0949
MBX: BCGT_0739
MAF: MAF_09360
MMIC: RN08_1034
MHAD: B586_06155
MBAI: MB901379_04011(hdhA_1)
MSHJ: MSHI_01040
MPHL: MPHLCCUG_00880(hdhA_2) MPHLCCUG_03862(kduD_2)
MTHN: 4412656_03807(hdhA_1) 4412656_04008(hdhA_2)
MAUU: NCTC10437_04635(hdhA_2)
MMAG: MMAD_45500
MALV: MALV_45780
MAUB: MAUB_41170
MPOF: MPOR_50370
MPHU: MPHO_28370
MBOK: MBOE_23810
MFLV: NCTC10271_00850(hdhA_2) NCTC10271_01431(fabG_10)
MAB: MAB_4632
MABB: MASS_4659
MCHE: BB28_23630
MSTE: MSTE_04802
MSAL: DSM43276_04463(hdhA_2)
MTER: 4434518_00836(hdhA_1)
MMIN: MMIN_25030
MHIB: MHIB_03680
NFA: NFA_24670
NFR: ERS450000_01631(hdhA_1) ERS450000_05266(hdhA_3)
NCY: NOCYR_3703(hdhA)
NAD: NCTC11293_03330(hdhA_1)
NWL: NWFMUON74_03900(hdhA)
GBR: Gbro_4568
GOR: KTR9_4545
GRU: GCWB2_22720(hdhA)
NCA: Noca_0427
NDK: I601_1650(rhlG)
PSIM: KR76_03205
AMD: AMED_2305(hdhA)
AMN: RAM_11735
AMM: AMES_2279(hdhA)
AMZ: B737_2280(hdhA)
AOI: AORI_5625(hdhA)
AMYY: YIM_15175(hdhA2)
AORI: SD37_27485
CYT: cce_2593
FVA: FV113G1_21970(hdhA)
AIT: AI2BBH_15620(hdhA)
CSAL: NBC122_01959(hdhA)
CJG: NCTC13459_00290(hdhA)
CANT: NCTC13489_01390(hdhA)
AG: BAA01384(hsdh)
 » show all
Reference
PMID:2007545
  Authors
Yoshimoto T, Higashi H, Kanatani A, Lin XS, Nagai H, Oyama H, Kurazono K, Tsuru D
  Title
Cloning and sequencing of the 7 alpha-hydroxysteroid dehydrogenase gene from Escherichia coli HB101 and characterization of the expressed enzyme.
  Journal
J Bacteriol 173:2173-9 (1991)
DOI:10.1128/JB.173.7.2173-2179.1991
  Sequence
LinkDB

KEGG   ENZYME: 1.1.1.159
Entry
EC 1.1.1.159                Enzyme                                 
Name
7alpha-hydroxysteroid dehydrogenase;
7alpha-hydroxy steroid dehydrogenase;
7alpha-HSDH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
7alpha-hydroxysteroid:NAD+ 7-oxidoreductase
Reaction(IUBMB)
cholate + NAD+ = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate + NADH + H+ [RN:R02792]
Reaction(KEGG)
R02792
Substrate
cholate [CPD:C00695];
NAD+ [CPD:C00003]
Product
3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate [CPD:C04643];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Catalyses the oxidation of the 7alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+.
History
EC 1.1.1.159 created 1976, modified 1980
Pathway
ec00121  Secondary bile acid biosynthesis
Orthology
K00076  7-alpha-hydroxysteroid dehydrogenase
Genes
ECOb1619(hdhA)
ECJJW1611(hdhA)
ECDECDH10B_1752(hdhA)
EBWBWG_1433(hdhA)
ECOKECMDS42_1289(hdhA)
ECEZ2624(hdhA)
ECSECs_2327(hdhA)
ECFECH74115_2331
ETWECSP_2183(hdhA)
ELXCDCO157_2160
EOIECO111_2088(hdhA)
EOJECO26_2347(hdhA)
EOHECO103_1759(hdhA)
ECOOECRM13514_2111(hdhA)
ECOHECRM13516_2013(hdhA)
ESLO3K_12140
ESOO3O_13495
ESMO3M_12105
ECKEC55989_1786(hdhA)
ECGE2348C_1704(hdhA)
EOKG2583_2013(hdhA)
ELRECO55CA74_09890
ELHETEC_1653
ECWEcE24377A_1827
EUNUMNK88_2078
ECPECP_1563
ENAECNA114_1666(hdhA)
ECOSEC958_1840(hdhA)
ECVAPECO1_702(hdhA)
ECOAAPECO78_11905
ECXEcHS_A1694
ECMEcSMS35_1580
ECYECSE_1740
ECRECIAI1_1670(hdhA)
ECQECED1_1819(hdhA)
EUMECUMN_1909(hdhA)
ECTECIAI39_1439(hdhA)
EOCCE10_1891(hdhA)
EBRECB_01588(hdhA)
EBLECD_01588(hdhA)
EBEB21_01578(hdhA)
EBDECBD_2026
ECIUTI89_C1807(hdhA)
EIHECOK1_1737
ECZECS88_1666(hdhA)
ECCc2011(hdhA)
ELOEC042_1787(hdhA)
ELNNRG857_08110
ESEECSF_1480
ECLEcolC_2011
EKOEKO11_2157
EKFKO11_14655(hdhA)
EABECABU_c18710(hdhA)
EDHEcDH1_2023
EDJECDH1ME8569_1562(hdhA)
ELUUM146_09060
ELWECW_m1785(hdhA)
ELLWFL_08740(hdhA)
ELCi14_1831(hdhA)
ELDi02_1831(hdhA)
ELPP12B_c1464(hdhA)
ELFLF82_0973(hdhA)
ECOLLY180_08440
ECOIECOPMV1_01714(hdhA)
ECOJP423_08660
EALEAKF1_ch4433
EMAC1192_04160
ESZFEM44_23020(hdhA)
SFLSF1644
SFNSFy_2351
SFSSFyv_2405
SFTNCTC1_01782(hdhA)
SSNSSON_1541(hdhA)
SBOSBO_1517(hdhA)
SBCSbBS512_E1806
SDYSDY_1838(hdhA)
SDZAsd1617_02472
SHQA0259_12120
PSHISAMEA2665130_1873(hdhA)
PATLKGI96_05555
ADPNCTC12871_00061(hdhA)
SACZAOT14_04240
STEKAXG53_18805
PMEXH4W19_17740(hdhA)
RGLCS053_01945 CS053_04875(hdhA)
PDSCAY62_02645
GHOAL542_12830
PPUTL483_14070
PPUNPP4_27250
PSAPST_0160
PFZAV641_10540
PLQAA042_19770
PPSYAOC04_07840
PSILPMA3_11740
PSEDDM292_18055
PUMHGP31_20755
PPSHG5J76_13495
PPHABVH74_17955
PTAENCTC10697_02058(hdhA)
PCRPcryo_2061
PRWPsycPRwf_0646
PSOPSYCG_11165
PURAOC03_04405 AOC03_05445
PSPGAK823_11385
PSYGAK825_11820
PSYCDABAL43B_2359(hdhA)
PSYYDLE54_03375
ACBA1S_3474
ARJDOM24_05960
ACHICDG60_11550
ABOUACBO_29550(hdhA)
COLWA3Q33_18515
CBERB5D82_11330
PHAPSHAa2129(hdhA)
PTNPTRA_a2582(hdhA) PTRA_b0693(hdhA)
PNGPNIG_a2776(hdhA)
SNANI6N98_14745
ZALAZF00_13560
AFUSEYZ66_13050
RHHE0Z06_14935
THIPN838_00855(hdhA) N838_28820
TBOGLT988_04030(hdhA)
PAURFGL86_03760
MSECLN244_04780
OCEGU3_12620
OCMCBP12_06080
OPFCBP31_12435
CUHBJN34_31130
BXEBxe_C0288
BXBDR64_8145
CTTCtCNB1_1310
CTESO987_07540
DIHG7047_10080
NETNeut_1072
AZIAzCIB_1506
AZDCDA09_09950
THUAC731_008890
HPYHP_1014
HEOC694_05250
HPJjhp_0409
HPAHPAG1_0432
HPSHPSH_02240
HHPHPSH112_02435
HHQHPSH169_02355
HHRHPSH417_02165
HPGHPG27_414
HPPHPP12_0429
HPBHELPY_0439
HPLHPB8_1130(hdhA)
HPCHPPC_02185
HCAHPPC18_02145
HPMHPSJM_02280
HPEHPELS_04580
HPOHMPREF4655_20677
HPIhp908_0449
HPQhp2017_0437
HPWhp2018_0439
HPUHPCU_02500
HEFHPF16_0436
HPFHPF30_0865
HEQHPF32_0876
HEXHPF57_0484
HPTHPSAT_02170
HPZHPKB_0437
HPVHPV225_0454
HPXHMPREF0462_0493
HENHPSNT_02330
HPHHPLT_02230
HEGHPGAM_02325
HPNHPIN_02030
HEPHPPN120_02200
HEUHPPN135_02215
HESHPSA_02180
HPYSHPSA20_0481
HCNHPB14_02110
HPDKHP_0420(hdhA)
HEYMWE_0518
HERC695_05255
HEIC730_05250
HPYAHPAKL117_02115
HPYKHPAKL86_03240
HPYOHPOK113_0440
HPYLHPOK310_0435
HPYBHPOKI102_02470
HPYCHPOKI112_02460
HPYDHPOKI128_02260
HPYEHPOKI154_02275
HPYFHPOKI422_02460
HPYGHPOKI673_02265
HPYHHPOKI828_02260
HPYJHPOKI898_02475
HPYRK747_10870
HPYIK750_03740
HPYUK751_05290
HPYMK749_03465
HEMK748_01880
HEBU063_1219
HEZU064_1223
HHEHH_1627
HACHac_1118(hdhA)
HMSHMU14020
HFEHFELIS_09110
HBIHBZC1_04430
HCEHCW_03695
HCMHCD_06040
HCPHCN_0775
HCBHCBAA847_1213
HHMBN341_13850
HTYBN2458_PEG0841
HBLXJ32_11090
HADCDV25_07120
HETBBW65_03700
HCLNCTC13205_01179(fabL)
HWIA0Z60_06755
HSHNHP194022_15110(hdhA)
WSUWS2222
TDNSuden_1227
SUASaut_0922
SULNFJR47_04390
SULGFJR48_06720
SULCCVO_05190
SPALFM071_06305
SSEIFJR45_04620
SBALHUE88_04550
SMASHUE87_07470
SKUSulku_0931
SULRB649_07490
CJECj0807
CJBBN148_0807
CJJCJJ81176_0828
CJUC8J_0758
CJNICDCCJ07001_780
CJICJSA_0763
CJMCJM1_0784
CJSCJS3_0855
CJPA911_03915
CJEJN564_00786
CJEUN565_00830
CJENN755_00827
CJEIN135_00852
CJERH730_04935
CJVMTVDSCj20_0816
CJYQZ67_00875(fabL)
CJQUC78_0770(fabL)
CJLPJ17_03920
CJWPJ18_03980
CJRCJE0898
CJDJJD26997_1203
CJZM635_08335
CJXBN867_08080
CFFCFF8240_0783
CFTCFF04554_0790
CFVCFVI03293_0964
CFXCFV97608_0847
CFZCSG_12070
CAMPCFT03427_0773
CFPCR44_03930
CCVCCV52592_1137
CHACHAB381_0584
CCOCCC13826_0121
CCOCCCON33237_1067
CLACLA_0625
CLRUPTC16701_0627
CLMUPTC16712_0633
CLQUPTC4110_0636
CLNUPTC3659_0721
CLLCONCH_0634
CCOLBN865_13120c
CCCG157_04865
CCQN149_0749
CCFYSQ_05365
CCYYSS_04040
CCOIYSU_05020
CCOFVC76_03920(fabL)
CCOOATE51_02030(fabL)
CAJCIG1485E_1090
CISCINS_0600
CVOCVOL_0619
CPELCPEL_0692
CAMRCAQ16704_0661
CSMCSUB8521_0665
CSFCSUB8523_0753
CGRACGRAC_1259
CURECUREO_0896
CHYOCHH_0712
CHVCHELV3228_0529
CSPFCSF_1172
CPINCPIN18020_0636
CCUNCCUN_0804
CLXCLAN_0896
CAVICAV_0650
CHWA2J15_002725
CAMZCVIC12175_0889
CAMYCSUIS_0947
COJCORN_0707
CUXCUP3940_1162
CRXCRECT_1198
CGEOCGEO_1020
CBLACBLAS_0865
CCORCCORG_0774
CARMCARM_0690
CMUCCMCT_0879
CSHOCSHOW_0956
CINFCINF_0722
CNVCNZW441b_0709
SDLSdel_1059
SBASulba_1205
SMULSMUL_1469
SHALSHALO_1439
SULSSdiek1_1516
SULJSJPD1_1446
SULTFA592_13535
ABUAbu_0873
ABTABED_0825
ABLA7H1H_0883
ASKEI285_02720
ATPATR_1094
ACIBACBT_1565
ACREACRYA_0869
ALANALANTH_1036
APOCAPORC_1370
AFCAFAEC_1436
ATHRATH_1317
ANTArnit_2128
AELLAELL_1015
AAQIAAQM_0898
ASUIASUIS_1701
ACLOACLO_0968
AVPAVENP_2042
ADZADFLV_1043
ALKALEK_2461
ALPLPB137_09490
AHSAHALO_1779
AMYTAMYT_1854
AMARAMRN_1809
ACAAACAN_1828
AMOLAMOL_1854
APAIAPAC_1684
HBVABIV_1642
HEBRAEBR_1977
AANAAANAER_1925
PACOAACT_1128
ARCABLL_1104
HYONNO_1099
NSANitsa_0918
SUNSUN_0808
SLHYH65_07615
SINUIMZ28_07650
NISNIS_0698
NAMNAMH_0962
NAPC3L23_04980
CMEDFE773_05965
CPAFC6V80_05200
PAUUE8A73_045650
SMXSM11_pC0473
SMIBN406_04893
RGARGR602_PC01386
KAIK32_36820(hdhA)
BMEBMEI0405 BMEI0406
BMELDK63_1019(hdhA) DK63_1020
BMIBMEA_A1670 BMEA_A1671
BMZBM28_A1622 BM28_A1623
BMGBM590_A1606 BM590_A1607
BMWBMNI_I1556 BMNI_I1557
BMEEDK62_1927 DK62_1928(hdhA)
BMFBAB1_1634 BAB1_1635
BMBBruAb1_1604 BruAb1_1605
BMCBAbS19_I15270 BAbS19_I15280
BAABAA13334_I01387 BAA13334_I01389
BABODK55_1585(hdhA) DK55_1586
BABRDO74_303 DO74_304(hdhA)
BABTDK49_1343(hdhA) DK49_1344
BABBDK48_533 DK48_534(hdhA)
BABUDK53_1569(hdhA) DK53_1570
BABSDK51_1972 DK51_1973(hdhA)
BABCDO78_1490(hdhA) DO78_1491
BMSBR1618 BR1619
BSIBS1330_I1612 BS1330_I1613
BSFBSS2_I1570 BSS2_I1571
BSUIBSSP1_I1639 BSSP1_I1640
BSUPBSPT1_I1656 BSPT1_I1657
BSUVBSPT2_I1638 BSPT2_I1639
BSUCBSSP2_I1643 BSSP2_I1644
BMTBSUIS_A1676 BSUIS_A1677
BSZDK67_709 DK67_710(hdhA)
BSVBSVBI22_A1612 BSVBI22_A1613
BSWIY71_07985 IY71_07990
BSGIY72_07725 IY72_07730
BOVBOV_1561 BOV_1562
BCSBCAN_A1655 BCAN_A1656
BSKBCA52141_I2599 BCA52141_I2601
BOLBCOUA_I1618 BCOUA_I1619
BCARDK60_1627(hdhA) DK60_1628
BCASDA85_07770 DA85_07775
BMRBMI_I1635 BMI_I1636
BPPBPI_I1675
BPVDK65_1879 DK65_1880(hdhA)
BCETV910_100402 V910_100403
BCEEV568_100447 V568_100448
BVLBF3285c1_1242 BF3285c1_1243
BRUBFS01_07770 BFS01_07775
BRJBKD03_13710 BKD03_13715
BIOBR141012304_11076 BR141012304_11077
BOSBSY19_1534 BSY19_1535(hdhA)
APRAG3A50_13370
METAY590_18880
MIVC4E04_17885
BNEDA69_08650
BDMEQG53_16165
BVYNCTC9239_00818(hdhA_3)
SILSPO3654
SITTM1040_2532
RUAD1823_17850
RUTFIU92_02140(hdhA)
JANJann_3883
RDERD1_1281
RLIRLO149_c035010
RPONG3256_16665
DSHDshi_0672
PGAPGA1_c29980
PGLPGA2_c27890
PGDGal_00421
PHPPhaeoP97_00508
PPICPhaeoP14_02768
PHQD1820_09675
OATOAN307_c05980
OAROA238_c36120
OTMOSB_28210(fabG_6)
OCTFTO60_13900
LMDMETH_02790
LEJETW24_03535
LAQUR2C4_14145
REDroselon_00663
CIDP73_4196
CMARIMCC12053_1256
CEHCEW89_10655
MALGMALG_02629
CONTQ29_14840 TQ29_15795
YPACCEW88_11930
YANAYJ57_05920
TPROGa0080559_TMP1389 Ga0080559_TMP3707
PABYGa0080574_TMP1631
SUAMBOO69_15645
SULZC1J03_02495
SULIC1J05_01330
SULDB5M07_15295
SPOTG6548_14490
SMEDJNX03_11455
SINLDSM14862_03001(fabG_9)
SPSESULPSESMR1_02760(fabG)
TOMBWR18_14185
RMMROSMUCSMR3_02595(bacC)
ROKRAK1035_0580
RIDRIdsm_00133(ydaD_1)
ROMEI983_09585
ROHFIU89_02020(fabG3)
AHTANTHELSMS3_01579
SAGUCDO87_07555
THAACFI11_03795
OCDFHY55_03165
MARUFIU81_02760(hdhA)
ROTFIV09_01880(fabG1)
MALUKU6B_50150
TGLHFZ77_14855
HATRC74_08740
RSPRSP_0684
RSHRsph17029_2339
RSQRsph17025_0546 Rsph17025_4255 Rsph17025_4256
RSKRSKD131_2042
CAZTLV780_02435 LV780_21205 LV780_21210(hdhA)
RHPLPB142_13640
RBLB6K69_15135
PDEPden_1754
PAMIJCM7686_1119
PYEA6J80_05285
PZHCX676_01685
PAROCUV01_13510
PARUCYR75_03350 CYR75_14110
PAMNJCM7685_2020
PMUTDPM13_03235
PARREOJ32_09285
PKDF8A10_12490
PPANESD82_14760
PLIAE4191_06715
PMAUCP157_01787(fabG_2)
PTPRCA23_c06370
RSUNHU_00279
RHMB5V46_02790
RHCRGUI_3217
RMBK529_012140
DAAAKL17_4764
DONBSK21_02145
THWBMG03_16065
TECAKL02_015555
LVSLOKVESSMR4R_00749(bacC)
RBGBG454_03170
GEHHYN69_14550
GFUKM031_12865
TAWEI545_08600
SALOEF888_09100
SEDIEBB79_18090
HMLHmaOT1_02265
BOOE2K80_17215
PSEBEOK75_11710
LITFPZ52_02725
PPRUFDP22_05250
PAEDG5B38_10445
MONG8E03_05335
PAMOBAR1_14065
PSHQF3W81_17390
POZI0K15_13820
PALWPSAL_023510(bacC)
PPAFI8N54_17130
CACTHZ995_04055
RBZB9057_11405
THASC6Y53_09995
CMAGCBW24_02840
FAPGR316_00300
GCEKYE46_03680
FAQG5B39_12655
NPPPP1Y_Mpl2814
NGFFRF71_11480
NOGGKE62_04200
SPHAD3Y57_09485
SLANGV829_01765
SBDATN00_02530
SPHBEP837_03639
SPPHKFK14_05365
SPHGAZE99_15690
SFLASPHFLASMR4Y_02341(benD)
SPHYCHN51_05505
PARJJ4G78_12865
TFVIDJ81_03145
ERYCP97_00135
PORLBG023_11863
PHZCHX26_05430
RMTIAI58_21185(hdhA)
CSOCLS_38520
PHXKGNDJEFE_01400
AARGAargi30884_01080
ABSIA9CBEGH2_02660
MTURv0927c
MTVRVBD_0927c
MTCMT0954
MRAMRA_0935
MTFTBFG_10945
MTBTBMG_03062
MTKTBSG_03082
MTZTBXG_003042
MTGMRGA327_05815
MTIMRGA423_05825
MTECCDC5079_0856
MTURCFBS_0975
MTLCCDC5180_0847
MTOMTCTRI2_0951
MTDUDA_0927c
MTNERDMAN_1028
MTJJ112_05005
MTUBMT7199_0946
MTUEJ114_04965
MTXM943_04860
MTULTBHG_00912
MTUTHKBT1_0975
MTUUHKBT2_0976
MTQHKBS1_0975
MBOBQ2027_MB0950C
MBBBCG_0979c
MBTJTY_0949
MBMBCGMEX_0950c
MBKK60_009920
MBXBCGT_0739
MAFMAF_09360
MMICRN08_1034
MCEMCAN_09271
MCQBN44_11019
MCVBN43_20397
MCXBN42_20736
MCZBN45_20227
MPAMAP_0871c MAP_1787c MAP_3222c
MAOMAP4_0566 MAP4_2989
MAVIRC58_02750 RC58_14840
MAVURE97_02755 RE97_14865
MAVMAV_1046 MAV_2460 MAV_4056
MITOCO_09170 OCO_10850 OCO_18870 OCO_24570 OCO_39040
MIAOCU_09210 OCU_19070 OCU_24440 OCU_39010
MIDMIP_01531 MIP_02649 MIP_03394 MIP_05898
MYOOEM_09340 OEM_23040 OEM_39580
MCHIAN480_05765 AN480_12375 AN480_20525
MIROCQ_09300 OCQ_17480 OCQ_23110 OCQ_40190
MMALCKJ54_04565 CKJ54_11155 CKJ54_18565
MMANMMAN_15090 MMAN_52540 MMAN_56040
MSAMycsm_05330
MULMUL_2481 MUL_4442
MMCMmcs_4362 Mmcs_4414 Mmcs_4606
MKMMkms_4448 Mkms_4501 Mkms_4694
MJLMjls_4742 Mjls_4795 Mjls_4989
MMIMMAR_1395 MMAR_4581
MMAEMMARE11_13620 MMARE11_43930
MMMW7S_04535 W7S_11870 W7S_19515
MLIMULP_01566 MULP_04798
MKNMKAN_09160 MKAN_22075
MYVG155_06610
MYEAB431_08675 AB431_14210 AB431_24220
MGOAFA91_12725
MHADB586_06155
MDXBTO20_29220
MSHGMSG_01350 MSG_04115
MFJMFLOJ_03030 MFLOJ_07660 MFLOJ_20240 MFLOJ_45100
MSTOMSTO_22680 MSTO_49310
MSIMMSIM_11130 MSIM_34450 MSIM_47800
MSAKMSAS_24690 MSAS_50450
MKUI2456_07405 I2456_21845 I2456_22895
MGROFZ046_00800 FZ046_02410
MXEMYXE_12230
MNVMNVI_08290 MNVI_29110
MPAGC0J29_08085 C0J29_25255
MNMMNVM_09660
MGORH0P51_07035 H0P51_23535
MCOOMCOO_22990 MCOO_25910 MCOO_46140
MBAIMB901379_04011(hdhA_1)
MSEOMSEO_01620 MSEO_17320 MSEO_29140
MPSEMPSD_15830 MPSD_47320
MSHOMSHO_19980 MSHO_21330
MHEKJMUB5695_01155 JMUB5695_02813 JMUB5695_03557
MGAUMGALJ_02830 MGALJ_34450 MGALJ_34980
MLJMLAC_04320
MBRDMBRA_24070 MBRA_25160
MSHJMSHI_01040
MKRMKOR_38740
MDFK0O62_23940
MMAMK3U93_06770 K3U93_19990
MHOLK3U96_04735 K3U96_07800
MHERK3U94_04745
MSENK3U95_23390 K3U95_23635
MPAEK0O64_08190 K0O64_23920
MSPGF6B93_18550
MOTLTS72_02290 LTS72_18165
MSMMSMEG_5584
MSGMSMEI_5435
MSBLJ00_27615
MSNLI99_27620
MSHLI98_27625
MVAMvan_4921 Mvan_4971
MGIMflv_1776 Mflv_1825
MSPMspyr1_11610 Mspyr1_12250
MCBMycch_4294
MNED174_22695
MYNMyAD_22255
MFTXA26_12480 XA26_13200
MPHLMPHLCCUG_00880(hdhA_2) MPHLCCUG_03862(kduD_2)
MVQMYVA_4738 MYVA_4790
MLLB1R94_20595 B1R94_23510
MRHMycrhN_2704 MycrhN_3273 MycrhN_6233
MTHN4412656_03807(hdhA_1) 4412656_04008(hdhA_2)
MHASMHAS_03412 MHAS_03449
MDUMDUV_09750 MDUV_52070 MDUV_52540
MCHTMCHIJ_23070 MCHIJ_48410
MAUUNCTC10437_04635(hdhA_2)
MMAGMMAD_45500
MMORMMOR_15270 MMOR_15800
MFXMFAL_36340
MAICMAIC_09170 MAIC_14680
MIJMINS_40180
MALVMALV_45780
MTYMTOK_27160 MTOK_37210
MPSCMPSYJ_19430
MARZMARA_48920 MARA_51280
MGADMGAD_21190 MGAD_33320 MGAD_34180
MHEVMHEL_31390 MHEL_38840
MSARMSAR_02520 MSAR_07970
MANYMANY_00360 MANY_29580
MAUBMAUB_41170
MPOFMPOR_50370
MPHUMPHO_28370
MMUCC1S78_004160
MMATMMAGJ_09730
MBOKMBOE_23810
MFGK6L26_07165 K6L26_07430
MSEIMSEDJ_32370 MSEDJ_59130
MFLVNCTC10271_00850(hdhA_2) NCTC10271_01431(fabG_10)
MABMAB_4632
MMVMYCMA_2556
MABBMASS_4659
MABLMMASJCM_4688
MCHEBB28_23630
MIZBAB75_26110
MSTEMSTE_04802
MSAOMYCSP_21595
MSALDSM43276_04463(hdhA_2)
MJDJDM601_0876
MTER4434518_00836(hdhA_1)
MMINMMIN_25030
MHIBMHIB_03680
MPAKMIU77_03490
NFANFA_24670
NFRERS450000_01631(hdhA_1) ERS450000_05266(hdhA_3)
NCYNOCYR_3703(hdhA)
NBRO3I_017480
NNONONO_c04060
NSLBOX37_16220
NSRNS506_00363
NTPCRH09_02755
NOZDMB37_39175
NODFOH10_29365
NAHF5544_20265
NADNCTC11293_03330(hdhA_1)
NWLNWFMUON74_03900(hdhA)
NIEKV110_19495
NTCKHQ06_08160
NHUH0264_03250
NYALTV02_29475
NGPLTT66_36145
ROPROP_pROB02-00930
GBRGbro_4568
GPOGPOL_c04750
GORKTR9_4545
GTABCM27_23790
GOCCXX93_12045
GRUGCWB2_22720(hdhA)
GOMD7316_03070
GAVC5O27_05690
GODGKZ92_21735
GJIH1R19_21880
GOILK459_10555
SPINKV203_10140
SCYAEJ357_02065
NCANoca_0427
NDKI601_1650(rhlG)
NBEBack2_27110
NANOG5V58_24635
NAROCFH99_02805
NPIG7071_03055
PSIMKR76_03205
AEBC6I20_03170
AMDAMED_2305(hdhA)
AMNRAM_11735
AMMAMES_2279(hdhA)
AMZB737_2280(hdhA)
AOIAORI_5625(hdhA)
AJAAJAP_11350
AABA4R43_15340
AMYYYIM_15175(hdhA2)
AORISD37_27485
AACDLWP59_30390
KPHYAOZ06_43315
PMADBAY61_23920
ASGFB03_02480
ABAIIMCC26256_11538
AYMYM304_02910 YM304_04710
AQZKSP35_14430
IAMHC251_22620
LSCKIK02_24535(hdhA) KIK02_24540
CYTcce_2593
CYCPCC7424_0224
CYJCyan7822_5662
LFSHFV01_24820 HFV01_24825(hdhA)
SCSSta7437_4706 Sta7437_4710
DSWQR90_06115
DEINDAAJ005_08310
FVAFV113G1_21970(hdhA)
FULC4N20_16245
FMOC4N19_06120
CPORBED41_06355
BISDXK01_008775
BVIRI6J59_17315
AITAI2BBH_15620(hdhA)
RBCBN938_2809 BN938_2810
PEPAQ505_11130
HYPA0257_02490
ASLAeqsu_0778
AEVEI546_09960
OCIFEZ18_04625
BIAGMA17_14425
ORHOrnrh_2066
ORIQ785_10220
CSALNBC122_01959(hdhA)
CJGNCTC13459_00290(hdhA)
CANTNCTC13489_01390(hdhA)
EFALFH779_06390
SULSYO3AOP1_0187
 » show all
Reference
1  [PMID:786279]
  Authors
Haslewood ES, Haslewood GA.
  Title
The specificity of a 7 alpha-hydroxy steroid dehydrogenase from Escherichia coli.
  Journal
Biochem J 157:207-10 (1976)
DOI:10.1042/bj1570207
Reference
2  [PMID:6945134]
  Authors
MacDonald IA, Roach PD.
  Title
Bile induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium absonum.
  Journal
Biochim Biophys Acta 665:262-9 (1981)
DOI:10.1016/0005-2760(81)90011-4
Reference
3  [PMID:4581498]
  Authors
Macdonald IA, Williams CN, Mahony DE.
  Title
7Alpha-hydroxysteroid dehydrogenase from Escherichia coli B: preliminary studies.
  Journal
Biochim Biophys Acta 309:243-53 (1973)
DOI:10.1016/0005-2744(73)90022-3
Reference
4  [PMID:236764]
  Authors
Macdonald IA, Williams CN, Mahony DE, Christie WM.
  Title
NAD- and NADP-dependent 7alpha-hydroxysteroid dehydrogenases from bacteroides fragilis.
  Journal
Biochim Biophys Acta 384:12-24 (1975)
DOI:10.1016/0005-2744(75)90091-1
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.159
IUBMB Enzyme Nomenclature: 1.1.1.159
ExPASy - ENZYME nomenclature database: 1.1.1.159
BRENDA, the Enzyme Database: 1.1.1.159
CAS: 39361-64-3
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