Entry |
|
Name |
D-amino-acid oxidase;
ophio-amino-acid oxidase (ambiguous);
L-amino acid:O2 oxidoreductase;
new yellow enzyme
|
Class |
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
|
Sysname |
D-amino-acid:oxygen oxidoreductase (deaminating)
|
Reaction(IUBMB) |
a D-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN: R01340]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
A flavoprotein (FAD). Wide specificity for D-amino acids. Also acts on glycine.
|
History |
EC 1.4.3.3 created 1961
|
Pathway |
ec00260 | Glycine, serine and threonine metabolism |
ec00311 | Penicillin and cephalosporin biosynthesis |
ec00330 | Arginine and proline metabolism |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
|
Genes |
PGUT: | 117672274 132709070 |
MUO: | 115479103 115479408(DAO) |
DRE: | 402994(dao.3) 405800(dao.2) 619259(dao.1) |
SRX: | 107727153 107727161 107741224 |
SANH: | 107654625 107696048 |
CCAR: | 109083180 109083183 109090353 |
CAUA: | 113048892 113048893 113048895 113049018 113049019 113049020 113072315 113096071 |
CGIB: | 127958662 127958663 127958664 128012958 |
PTET: | 122346073 122346075 122346076(dao.3) |
LROH: | 127165224 127165225 |
MAMB: | 125266435 125266438 125266439 |
CIDE: | 127512514 127512516 |
CERY: | 137016991 137034016 137034017 137034324(dao.3) |
TROS: | 130564729 130564745 |
MANU: | 129439851 129439852 |
BSPL: | 114862208 114862212 |
PSPA: | 121297138 121299990 121307717 |
ARUT: | 117428576 117973385 |
BFO: | 118403292 118419967 118421772 118422912 118423357 118423358 118431818 |
BBEL: | 109466174 109467956 109479126 109479136 109486315 |
DSI: | Dsimw501_GD23432(Dsim_GD23432) |
ACOZ: | 120948434 120950806 |
AARA: | 120898509 120908475 |
AMER: | 121588091 121589806 |
ASTE: | 118505292 118517184 118517591 |
AFUN: | 125765853 125775209 |
AMOU: | 128300863 128310350 |
AALI: | 118468870 118468872 |
AALB: | 109409546 109423386 109423387 115254205 115268049 |
ASUA: | 134224817 134224818 |
CQU: | CpipJ_CPIJ002817 CpipJ_CPIJ007272 CpipJ_CPIJ007273 |
CPII: | 120423370 120423371 |
PPYR: | 116165934 116172507 116180529 116180964 116181229 116181273 |
CCRN: | 123292112 123292113 |
PPOI: | 119096798 119097049 119104577 |
RSAN: | 119372508 119372509 119372510 |
CEL: | CELE_Y69A2AR.5(daao-1) |
CBR: | CBG_13882(Cbr-daao-1) |
HRJ: | 124270537 124270563 124270572 |
HASI: | 137291654 137291655 137291656 |
CANU: | 128160681 128168372 |
CVN: | 111108560 111118058 111118059 111118061 111122379 111122380 111122381 |
PMAX: | 117324933 117325397 |
MCAF: | 127727017 127727018 |
NVE: | 5507536 5513702 5519737 |
EPA: | 110233699 110248305 110248306 110248307 |
PDAM: | 113674980 113684265 113686080 |
SPIS: | 111319960 111322597 111337230 |
TAD: | TRIADDRAFT_60526 TRIADDRAFT_60527 TRIADDRAFT_64116 |
KLA: | KLLA0_A02475g KLLA0_A08492g KLLA0_D07568g |
KMX: | KLMA_10437(DAO1) KLMA_20774(dao1) KLMA_30640(dao1) |
LTH: | KLTH0A02772g KLTH0H13090g |
ZRO: | ZYRO0A12804g ZYRO0B01892g ZYRO0G21538g |
NCS: | NCAS_0J00530(NCAS0J00530) |
NDI: | NDAI_0C06370(NDAI0C06370) |
TPF: | TPHA_0A02240(TPHA0A02240) |
TGB: | HG536_0B06350 HG536_0F02800 |
TDL: | TDEL_0C00920(TDEL0C00920) TDEL_0D02660(TDEL0D02660) |
ZMK: | HG535_0C04640 HG535_0H02090 |
DHA: | DEHA2B06754g DEHA2E12760g DEHA2G21318g |
PIC: | PICST_33517(IFG3) PICST_57912(DAO1) PICST_83340(DAO2) |
PGU: | PGUG_00766 PGUG_02493 PGUG_03358 PGUG_04682 PGUG_05057 |
SPAA: | SPAPADRAFT_55523 SPAPADRAFT_58036 SPAPADRAFT_58710 |
LEL: | PVL30_001547(DAO1) PVL30_004205 |
LBG: | 92208034(LODBEIA_P28380) 92210325(LODBEIA_P51290) |
CAL: | CAALFM_C103670CA(DAO1) CAALFM_C403380CA(DAO2) CAALFM_C500450CA(IFG3) |
CTP: | CTRG_04578 CTRG_05258 |
COT: | CORT_0B10010 CORT_0E03480 CORT_0E04630 CORT_0E06250 |
CDU: | CD36_03420 CD36_43150 CD36_50460 |
CTEN: | 18248977(IFG3) 18248986(PSN45_003643) 90982105(PSN45_003652) |
CLU: | CLUG_00102 CLUG_02408 CLUG_02525 |
CLUS: | A9F13_07g03487 A9F13_20g00220 A9F13_24g00319 |
CAUR: | CJI96_0002763 CJI96_0003851 CJI96_0004484 CJI96_0005287 |
PKZ: | C5L36_0A09980 C5L36_0B10275 C5L36_0C03060 C5L36_0C04650 C5L36_0C04660 C5L36_0C07960 |
BNN: | FOA43_002525 FOA43_002526 FOA43_004751 |
BBRX: | BRETT_000075 BRETT_001651 BRETT_004892 |
OPA: | HPODL_00899 HPODL_02082 HPODL_02165 HPODL_02400 HPODL_02914 HPODL_05094 |
YLI: | 2907652(YALI2_E00907g) 2907946(YALI2_E00856g) 2909003(YALI2_F00777g) 2911832(YALI2_E01352g) |
SLB: | AWJ20_2748 AWJ20_3355 |
NTE: | NEUTE1DRAFT78436(NEUTE1DRAFT_78436) |
SMP: | 10803900(SMAC4_04682) |
PAN: | PODANS72p037 PODANSg5857 |
TTT: | THITE_2113588 THITE_2114333 |
MTM: | MYCTH_2296164 MYCTH_39133 MYCTH_60632 |
CTHR: | CTHT_0037050 CTHT_0060620 |
SSCK: | SPSK_00810 SPSK_09289 SPSK_09377 SPSK_09463 |
FGR: | FGSG_01730 FGSG_13617 |
FPU: | FPSE_05934 FPSE_11427 |
FPOA: | FPOAC1_001844 FPOAC1_004218 FPOAC1_011995 |
FVN: | FVRRES_02071 FVRRES_04689 FVRRES_07817 FVRRES_13063 |
FVR: | FVEG_03267 FVEG_06262 FVEG_09824 FVEG_09912 FVEG_11222 |
FOX: | FOXG_04878 FOXG_08416 FOXG_10198 FOXG_10896 FOXG_10976 FOXG_12043 FOXG_13789 FOXG_15614 FOXG_16070 FOXG_16965 |
NHE: | NECHADRAFT_102418 NECHADRAFT_49089 NECHADRAFT_56002 NECHADRAFT_74001 NECHADRAFT_83204 NECHADRAFT_83205 NECHADRAFT_88109 NECHADRAFT_88675 NECHADRAFT_92259 NECHADRAFT_94818 |
FFC: | NCS54_00007200 NCS54_00231500 NCS54_00341000 NCS54_00346500 NCS54_00456200 NCS54_00480500 NCS54_00498900 NCS54_00895600 NCS54_00983300 NCS54_00983400 NCS54_01172100 |
FKR: | NCS57_00004400 NCS57_00226900 NCS57_00343100 NCS57_00352000 NCS57_00461200 NCS57_00505900 NCS57_00506000 NCS57_00517400 NCS57_00536800 NCS57_01162900 NCS57_01468000 |
FMU: | J7337_000052 J7337_000144 J7337_004523 J7337_006168 J7337_008080 J7337_011907 |
TRE: | TRIREDRAFT_2521 TRIREDRAFT_68956 |
TRR: | M419DRAFT_103660 M419DRAFT_72306 |
TATV: | 25776337(TrAtP1_007087) 25785577(TrAtP1_007378) |
TASP: | 36616723(TrAFT101_008000) 36618986(TrAFT101_006285) 36619380(TrAFT101_011424) |
MAW: | 19245748(DAO1_1) 19249069(J3458_000778) 19251878(IFG3_1) |
MAJ: | MAA_02320 MAA_07041 MAA_10016 |
MBRN: | 26238088(OXDA) 26239906(dao1_0) 26247253(dao1_1) |
PCHM: | VFPPC_01345 VFPPC_04858 VFPPC_09277 |
AMUS: | LMH87_011170 LMH87_012270 |
PLJ: | 28884247(PLICBS_005516) 28884684(PLICBS_005906) 28886484(PLICBS_001837) 28888672(PLICBS_003841) 28890552(PLICBS_005085) 28892272(PLICBS_009977) |
PTKZ: | JDV02_000014(DAO1_1) JDV02_003013(IFG3_1) JDV02_003863(DAO1_2) JDV02_007279(IFG3_2) JDV02_008685 JDV02_010045 |
VAL: | VDBG_03332 VDBG_03471 |
VDA: | VDAG_02236 VDAG_09915 |
CFJ: | CFIO01_08378 CFIO01_08563 CFIO01_11282 CFIO01_12986 |
CHIG: | CH63R_05462 CH63R_13580 |
CDET: | 87947162(CDEST_10662) 87948429(CDEST_11929) |
ELA: | UCREL1_11223 UCREL1_3739 UCREL1_4261 UCREL1_8274 UCREL1_8453 |
PFY: | PFICI_02939 PFICI_03892 PFICI_04252 PFICI_06261 PFICI_08522 PFICI_08563 PFICI_09756 PFICI_11946 |
SSL: | SS1G_08525 SS1G_13657 |
BFU: | BCIN_12g04240(Bcdao1) BCIN_13g00810(Bcdao3) |
MBE: | MBM_02024 MBM_02443 MBM_03167 MBM_05129 MBM_09687 |
PSCO: | LY89DRAFT_688126 LY89DRAFT_707731 LY89DRAFT_769781 LY89DRAFT_779260 |
GLZ: | GLAREA_00037 GLAREA_09629 GLAREA_09933 GLAREA_12736 |
AFM: | AFUA_5G11290 AFUA_5G13940 |
ACT: | ACLA_014370 ACLA_016940 |
NFI: | NFIA_004660 NFIA_073030 NFIA_075980 |
AOR: | AO090005000932 AO090012000898 AO090026000714 AO090113000084 |
ANG: | An01g02430 An06g02340 An14g05380 |
AFV: | AFLA_002618 AFLA_005580 AFLA_009800 |
ALUC: | AKAW2_20429A AKAW2_41172A |
ACHE: | ACHE_41126A ACHE_51214A ACHE_60836A |
APUU: | APUU_11970A APUU_12300A APUU_20065S APUU_20154A APUU_40254A APUU_50261A |
PCS: | N7525_000098 N7525_006823 N7525_007039 N7525_009069 |
PDP: | PDIP_60930 PDIP_81590 |
POU: | POX_d05173 POX_d05210 POX_d06014 POX_e07171 |
TMF: | EYB26_001732 EYB26_003706 EYB26_004870 EYB26_008112 |
TRG: | TRUGW13939_00347 TRUGW13939_01718 TRUGW13939_02197 TRUGW13939_05182 TRUGW13939_08536 TRUGW13939_10389 TRUGW13939_10897 TRUGW13939_11803 |
CIM: | CIMG_05805 CIMG_08541 CIMG_09124 |
CPW: | 9692564(D8B26_007527) 9695967(D8B26_004657) |
URE: | UREG_02605 UREG_04496 UREG_05175 |
AJE: | HCAG_00881 HCAG_03187 |
BGH: | BDBG_01055 BDBG_06928 |
PNO: | SNOG_08645 SNOG_08792 SNOG_10311 SNOG_11599 |
PTRR: | 6338985(PtrM4_028160) 6342873(PtrM4_115470) |
BZE: | COCCADRAFT_107125 COCCADRAFT_110196 COCCADRAFT_22330 COCCADRAFT_39756 |
BSC: | COCSADRAFT_100696 COCSADRAFT_166933 |
BOR: | COCMIDRAFT_10055 COCMIDRAFT_29064 COCMIDRAFT_89225 |
AALT: | CC77DRAFT_1025005 CC77DRAFT_1092670 CC77DRAFT_949039 |
ARAB: | EKO05_0003849 EKO05_0009234 |
ZTR: | MYCGRDRAFT_108629 MYCGRDRAFT_62699 |
PFJ: | MYCFIDRAFT_210959 MYCFIDRAFT_212492 |
FFU: | CLAFUR5_05841 CLAFUR5_11024 |
CBET: | CB0940_06796 CB0940_08860 |
BCOM: | BAUCODRAFT_302218 BAUCODRAFT_31180 |
NPA: | UCRNP2_10370 UCRNP2_1662 UCRNP2_380 UCRNP2_5007 UCRNP2_9137 UCRNP2_9880 |
CNE: | CNE00330 CNF01770 CNG00410 |
CNB: | CNBE0250 CNBF2940 CNBG4370 |
CNG: | CNAG_02532 CNAG_03562 CNAG_05802 |
CGI: | CGB_E0280W CGB_F4300W CGB_G6310W |
CDEU: | CNBG_1742 CNBG_2060 CNBG_4227 |
KMG: | 30160429(I203_104438) 30163805(I203_103015) 30168292(I203_105081) |
KNE: | 92180467(IAR55_003209) 92182003(IAR55_004745) 92184114(IAR55_006856) |
TASA: | A1Q1_01063 A1Q1_03993 |
CCAC: | CcaHIS019_0104690(CcaverHIS019_0104690) CcaHIS019_0113470(CcaverHIS019_0113470) CcaHIS019_0304260(CcaverHIS019_0304260) CcaHIS019_0411230(CcaverHIS019_0411230) CcaHIS019_0700260(CcaverHIS019_0700260) |
PPL: | POSPLDRAFT_101343 POSPLDRAFT_93596 |
TVS: | TRAVEDRAFT_138608 TRAVEDRAFT_51132 TRAVEDRAFT_65970 TRAVEDRAFT_91618 |
DSQ: | DICSQDRAFT_157633 DICSQDRAFT_167952 DICSQDRAFT_48303 |
PCO: | PHACADRAFT_172168 PHACADRAFT_210477 PHACADRAFT_24819 PHACADRAFT_258655 |
SHS: | STEHIDRAFT_127642 STEHIDRAFT_161404 STEHIDRAFT_68352 |
HIR: | HETIRDRAFT_117157 HETIRDRAFT_239418 HETIRDRAFT_307723 HETIRDRAFT_482075 |
PSQ: | PUNSTDRAFT_129561 PUNSTDRAFT_137505 PUNSTDRAFT_44417 |
ADL: | AURDEDRAFT_115921 AURDEDRAFT_161209 AURDEDRAFT_184116 AURDEDRAFT_75112 |
FME: | FOMMEDRAFT_154908 FOMMEDRAFT_161622 |
GTR: | GLOTRDRAFT_122190 GLOTRDRAFT_140139 GLOTRDRAFT_67555 |
CCI: | CC1G_05515 CC1G_15725 |
ABP: | AGABI1DRAFT108801(AGABI1DRAFT_108801) AGABI1DRAFT78624(AGABI1DRAFT_78624) |
ABV: | AGABI2DRAFT208623(AGABI2DRAFT_208623) AGABI2DRAFT208642(AGABI2DRAFT_208642) |
MPR: | MPER_01474 MPER_03223 MPER_13168 |
MRR: | Moror_15161 Moror_7126 Moror_7127 Moror_9955 |
MORE: | E1B28_010899 E1B28_010900 |
SCM: | SCHCO_01171504(SCHCODRAFT_01171504) SCHCO_02611538(SCHCODRAFT_02611538) SCHCO_02624620(SCHCODRAFT_02624620) SCHCO_02633490(SCHCODRAFT_02633490) SCHCO_02637823(SCHCODRAFT_02637823) |
CPUT: | CONPUDRAFT_109547 CONPUDRAFT_115900 CONPUDRAFT_129240 |
SLA: | SERLADRAFT_457084 SERLADRAFT_458189 |
UMA: | UMAG_05703 UMAG_11649 |
PFP: | PFL1_01912 PFL1_02372 |
SGRA: | EX895_002684 EX895_006053 |
PGR: | PGTG_01689 PGTG_18680 |
RIE: | OCT59_003979 OCT59_005359 OCT59_020494 |
DDI: | DDB_G0273291(ddo-2) DDB_G0273783(ddo-1) |
PIF: | PITG_08110 PITG_08125 |
PSOJ: | PHYSODRAFT_319218 PHYSODRAFT_528544 |
SPAR: | SPRG_03672 SPRG_17080 |
MUL: | MUL_1659(aao_1) MUL_2926(aao) |
MMI: | MMAR_1462 MMAR_2477(aao_1) MMAR_2801(aao) |
MMAE: | MMARE11_24000(aao_1) MMARE11_27230(aao) |
MLI: | MULP_02569(aao) MULP_03134(aao_1) |
MSHO: | MSHO_37360(aao_1) MSHO_42110(aao_2) |
MSTO: | MSTO_06630(aao) MSTO_11030 |
MSIM: | MSIM_40750(aao_1) MSIM_50640(aao_2) |
MSAK: | MSAS_07960(aao_1) MSAS_18330(aao_2) |
MBAI: | MB901379_02306 MB901379_02594 |
MHEK: | JMUB5695_04488(aao) |
MMAM: | K3U93_11445 K3U93_12940 |
NAH: | F5544_16655 F5544_20745 |
NSPU: | IFM12276_24090(aao) |
SVT: | SVTN_31495 SVTN_33545 |
SCX: | AS200_09095 AS200_29990 |
SLE: | sle_10800(sle_10800) sle_33170(sle_33170) |
SPUN: | BFF78_06535 BFF78_37385 |
SAST: | CD934_03375 CD934_22680 |
SLIA: | HA039_04415 HA039_16210 |
SPEU: | CGZ69_29245 CGZ69_31770 |
SYUN: | MOV08_08870 MOV08_15915 |
SCOA: | QU709_04790 QU709_38385 |
SINN: | ABB07_05055 ABB07_37290 |
STPB: | QR97_18110 QR97_18975 |
SMIB: | SMIR_01015 SMIR_36195 |
SCT: | SCAT_2906 SCAT_4156 SCAT_p0271 |
SCY: | SCATT_28970 SCATT_41430 SCATT_p14710 |
PSUL: | AU252_09265 AU252_13920 |
NAQU: | ENKNEFLB_01867(aao) |
NRN: | SHK17_04235 SHK17_06825 |
AMYZ: | HUW46_00221(aao_1) HUW46_08167(aao_2) |
MICB: | MicB006_5064 MicB006_5075 |
MSAG: | GCM10017556_37480 GCM10017556_56640 |
MCRA: | ID554_09900 ID554_09910 ID554_10090 ID554_27215 |
VER: | HUT12_03430 HUT12_13800 |
MCHL: | PVK74_00910 PVK74_00965 |
MCAY: | PVK37_12955 PVK37_23170 |
AMS: | AMIS_14610 AMIS_39880 |
ACTN: | L083_3882 L083_4798(aao) L083_4810 |
AIH: | Aiant_29890(aao_1) Aiant_29900(aao_2) |
ACTL: | L3i22_058560 L3i22_094770(aao) |
ASIC: | Q0Z83_029290 Q0Z83_072730 |
AOU: | ACTOB_007053 ACTOB_007446 |
ACTE: | ACTI_35650 ACTI_58700 |
PLAB: | C6361_09360 C6361_27195 |
PLAT: | C6W10_05870 C6W10_25355 |
PSUU: | Psuf_006270 Psuf_039050 |
DVC: | Dvina_05660 Dvina_06075 Dvina_08015 |
DFU: | Dfulv_00805 Dfulv_07435 |
DROS: | Drose_00720 Drose_07775 |
DAUR: | Daura_07455 Daura_28770 Daura_28785 |
DMAT: | Dmats_05555 Dmats_07525 |
DACT: | KZZ52_00815 KZZ52_07310 |
CCAZ: | COUCH_20700 COUCH_34545 |
SCYS: | NIES4073_76230(aao) |
» show all
|
Reference |
|
Authors |
DIXON M, KLEPPE K. |
Title |
D-AMINO ACID OXIDASE. I. DISSOCIATION AND RECOMBINATION OF THE HOLOENZYME. |
Journal |
|
Reference |
2 |
Authors |
Dixon M, Kleppe K. |
Title |
D-Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence. |
Journal |
Biochim Biophys Acta 96:368-382 (1965) |
Reference |
|
Authors |
DIXON M, KLEPPE K. |
Title |
D-AMINO ACID OXIDASE. 3. EFFECT OF PH. |
Journal |
|
Reference |
|
Authors |
MASSEY V, PALMER G, BENNETT R. |
Title |
The purification and some properties of D-amino acid oxidase. |
Journal |
|
Reference |
5 |
Authors |
Meister A, Wellner D. |
Title |
Flavoprotein amino acid oxidase. |
Journal |
In: Boyer PD, Lardy H, Myrback K (eds). The Enzymes. 2nd ed. Vol. 7. New York: Academic Press; 1963. p. 609-648. |
Other DBs |
ExplorEnz - The Enzyme Database: | 1.4.3.3 |
ExPASy - ENZYME nomenclature database: | 1.4.3.3 |
BRENDA, the Enzyme Database: | 1.4.3.3 |
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LinkDB |
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