Entry
Name
D-amino-acid oxidase;
ophio-amino-acid oxidase (ambiguous);
L-amino acid:O2 oxidoreductase;
new yellow enzyme
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
D-amino-acid:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
a D-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN:
R01340 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoprotein (FAD). Wide specificity for D-amino acids. Also acts on glycine.
History
EC 1.4.3.3 created 1961
Pathway
ec00260 Glycine, serine and threonine metabolism
ec00311 Penicillin and cephalosporin biosynthesis
ec00330 Arginine and proline metabolism
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
PGUT : 117672274 132709070
MUO : 115479103 115479408(DAO)
DRE : 402994(dao.3) 405800(dao.2) 619259(dao.1)
SRX : 107727153 107727161 107741224
SANH : 107654625 107696048
CCAR : 109083180 109083183 109090353
CAUA : 113048892 113048893 113048895 113049018 113049019 113049020 113072315 113096071
CGIB : 127958662 127958663 127958664 128012958
PTET : 122346073 122346075 122346076(dao.3)
LROH : 127165224 127165225
MAMB : 125266435 125266438 125266439
CIDE : 127512514 127512516
CERY : 137016991 137034016 137034017 137034324(dao.3)
TROS : 130564729 130564745
MANU : 129439851 129439852
BSPL : 114862208 114862212
PSPA : 121297138 121299990 121307717
ARUT : 117428576 117973385
BFO : 118403292 118419967 118421772 118422912 118423357 118423358 118431818
BBEL : 109466174 109467956 109479126 109479136 109486315
DSI : Dsimw501_GD23432(Dsim_GD23432)
ACOZ : 120948434 120950806
AARA : 120898509 120908475
AMER : 121588091 121589806
ASTE : 118505292 118517184 118517591
AFUN : 125765853 125775209
AMOU : 128300863 128310350
AALI : 118468870 118468872
AALB : 109409546 109423386 109423387 115254205 115268049
ASUA : 134224817 134224818
CQU : CpipJ_CPIJ002817 CpipJ_CPIJ007272 CpipJ_CPIJ007273
CPII : 120423370 120423371
PPYR : 116165934 116172507 116180529 116180964 116181229 116181273
CCRN : 123292112 123292113
PPOI : 119096798 119097049 119104577
RSAN : 119372508 119372509 119372510
CEL : CELE_Y69A2AR.5(daao-1)
CBR : CBG_13882(Cbr-daao-1)
HRJ : 124270537 124270563 124270572
HASI : 137291654 137291655 137291656
CANU : 128160681 128168372
CVN : 111108560 111118058 111118059 111118061 111122379 111122380 111122381
PMAX : 117324933 117325397
MCAF : 127727017 127727018
NVE : 5507536 5513702 5519737
EPA : 110233699 110248305 110248306 110248307
PDAM : 113674980 113684265 113686080
SPIS : 111319960 111322597 111337230
TAD : TRIADDRAFT_60526 TRIADDRAFT_60527 TRIADDRAFT_64116
KLA : KLLA0_A02475g KLLA0_A08492g KLLA0_D07568g
KMX : KLMA_10437(DAO1) KLMA_20774(dao1) KLMA_30640(dao1)
LTH : KLTH0A02772g KLTH0H13090g
ZRO : ZYRO0A12804g ZYRO0B01892g ZYRO0G21538g
NCS : NCAS_0J00530(NCAS0J00530)
NDI : NDAI_0C06370(NDAI0C06370)
TPF : TPHA_0A02240(TPHA0A02240)
TGB : HG536_0B06350 HG536_0F02800
TDL : TDEL_0C00920(TDEL0C00920) TDEL_0D02660(TDEL0D02660)
ZMK : HG535_0C04640 HG535_0H02090
DHA : DEHA2B06754g DEHA2E12760g DEHA2G21318g
PIC : PICST_33517(IFG3) PICST_57912(DAO1) PICST_83340(DAO2)
PGU : PGUG_00766 PGUG_02493 PGUG_03358 PGUG_04682 PGUG_05057
SPAA : SPAPADRAFT_55523 SPAPADRAFT_58036 SPAPADRAFT_58710
LEL : PVL30_001547(DAO1) PVL30_004205
LBG : 92208034(LODBEIA_P28380) 92210325(LODBEIA_P51290)
CAL : CAALFM_C103670CA(DAO1) CAALFM_C403380CA(DAO2) CAALFM_C500450CA(IFG3)
CTP : CTRG_04578 CTRG_05258
COT : CORT_0B10010 CORT_0E03480 CORT_0E04630 CORT_0E06250
CDU : CD36_03420 CD36_43150 CD36_50460
CTEN : 18248977(IFG3) 18248986(PSN45_003643) 90982105(PSN45_003652)
CLU : CLUG_00102 CLUG_02408 CLUG_02525
CLUS : A9F13_07g03487 A9F13_20g00220 A9F13_24g00319
CAUR : CJI96_0002763 CJI96_0003851 CJI96_0004484 CJI96_0005287
PKZ : C5L36_0A09980 C5L36_0B10275 C5L36_0C03060 C5L36_0C04650 C5L36_0C04660 C5L36_0C07960
BNN : FOA43_002525 FOA43_002526 FOA43_004751
BBRX : BRETT_000075 BRETT_001651 BRETT_004892
OPA : HPODL_00899 HPODL_02082 HPODL_02165 HPODL_02400 HPODL_02914 HPODL_05094
YLI : 2907652(YALI2_E00907g) 2907946(YALI2_E00856g) 2909003(YALI2_F00777g) 2911832(YALI2_E01352g)
SLB : AWJ20_2748 AWJ20_3355
NTE : NEUTE1DRAFT78436(NEUTE1DRAFT_78436)
SMP : 10803900(SMAC4_04682)
PAN : PODANS72p037 PODANSg5857
TTT : THITE_2113588 THITE_2114333
MTM : MYCTH_2296164 MYCTH_39133 MYCTH_60632
CTHR : CTHT_0037050 CTHT_0060620
SSCK : SPSK_00810 SPSK_09289 SPSK_09377 SPSK_09463
FGR : FGSG_01730 FGSG_13617
FPU : FPSE_05934 FPSE_11427
FPOA : FPOAC1_001844 FPOAC1_004218 FPOAC1_011995
FVN : FVRRES_02071 FVRRES_04689 FVRRES_07817 FVRRES_13063
FVR : FVEG_03267 FVEG_06262 FVEG_09824 FVEG_09912 FVEG_11222
FOX : FOXG_04878 FOXG_08416 FOXG_10198 FOXG_10896 FOXG_10976 FOXG_12043 FOXG_13789 FOXG_15614 FOXG_16070 FOXG_16965
NHE : NECHADRAFT_102418 NECHADRAFT_49089 NECHADRAFT_56002 NECHADRAFT_74001 NECHADRAFT_83204 NECHADRAFT_83205 NECHADRAFT_88109 NECHADRAFT_88675 NECHADRAFT_92259 NECHADRAFT_94818
FFC : NCS54_00007200 NCS54_00231500 NCS54_00341000 NCS54_00346500 NCS54_00456200 NCS54_00480500 NCS54_00498900 NCS54_00895600 NCS54_00983300 NCS54_00983400 NCS54_01172100
FKR : NCS57_00004400 NCS57_00226900 NCS57_00343100 NCS57_00352000 NCS57_00461200 NCS57_00505900 NCS57_00506000 NCS57_00517400 NCS57_00536800 NCS57_01162900 NCS57_01468000
FMU : J7337_000052 J7337_000144 J7337_004523 J7337_006168 J7337_008080 J7337_011907
TRE : TRIREDRAFT_2521 TRIREDRAFT_68956
TRR : M419DRAFT_103660 M419DRAFT_72306
TATV : 25776337(TrAtP1_007087) 25785577(TrAtP1_007378)
TASP : 36616723(TrAFT101_008000) 36618986(TrAFT101_006285) 36619380(TrAFT101_011424)
MAW : 19245748(DAO1_1) 19249069(J3458_000778) 19251878(IFG3_1)
MAJ : MAA_02320 MAA_07041 MAA_10016
MBRN : 26238088(OXDA) 26239906(dao1_0) 26247253(dao1_1)
PCHM : VFPPC_01345 VFPPC_04858 VFPPC_09277
AMUS : LMH87_011170 LMH87_012270
PLJ : 28884247(PLICBS_005516) 28884684(PLICBS_005906) 28886484(PLICBS_001837) 28888672(PLICBS_003841) 28890552(PLICBS_005085) 28892272(PLICBS_009977)
PTKZ : JDV02_000014(DAO1_1) JDV02_003013(IFG3_1) JDV02_003863(DAO1_2) JDV02_007279(IFG3_2) JDV02_008685 JDV02_010045
VAL : VDBG_03332 VDBG_03471
VDA : VDAG_02236 VDAG_09915
CFJ : CFIO01_08378 CFIO01_08563 CFIO01_11282 CFIO01_12986
CHIG : CH63R_05462 CH63R_13580
CDET : 87947162(CDEST_10662) 87948429(CDEST_11929)
ELA : UCREL1_11223 UCREL1_3739 UCREL1_4261 UCREL1_8274 UCREL1_8453
PFY : PFICI_02939 PFICI_03892 PFICI_04252 PFICI_06261 PFICI_08522 PFICI_08563 PFICI_09756 PFICI_11946
SSL : SS1G_08525 SS1G_13657
BFU : BCIN_12g04240(Bcdao1) BCIN_13g00810(Bcdao3)
MBE : MBM_02024 MBM_02443 MBM_03167 MBM_05129 MBM_09687
PSCO : LY89DRAFT_688126 LY89DRAFT_707731 LY89DRAFT_769781 LY89DRAFT_779260
GLZ : GLAREA_00037 GLAREA_09629 GLAREA_09933 GLAREA_12736
AFM : AFUA_5G11290 AFUA_5G13940
ACT : ACLA_014370 ACLA_016940
NFI : NFIA_004660 NFIA_073030 NFIA_075980
AOR : AO090005000932 AO090012000898 AO090026000714 AO090113000084
ANG : An01g02430 An06g02340 An14g05380
AFV : AFLA_002618 AFLA_005580 AFLA_009800
ALUC : AKAW2_20429A AKAW2_41172A
ACHE : ACHE_41126A ACHE_51214A ACHE_60836A
APUU : APUU_11970A APUU_12300A APUU_20065S APUU_20154A APUU_40254A APUU_50261A
PCS : N7525_000098 N7525_006823 N7525_007039 N7525_009069
PDP : PDIP_60930 PDIP_81590
POU : POX_d05173 POX_d05210 POX_d06014 POX_e07171
TMF : EYB26_001732 EYB26_003706 EYB26_004870 EYB26_008112
TRG : TRUGW13939_00347 TRUGW13939_01718 TRUGW13939_02197 TRUGW13939_05182 TRUGW13939_08536 TRUGW13939_10389 TRUGW13939_10897 TRUGW13939_11803
CIM : CIMG_05805 CIMG_08541 CIMG_09124
CPW : 9692564(D8B26_007527) 9695967(D8B26_004657)
URE : UREG_02605 UREG_04496 UREG_05175
AJE : HCAG_00881 HCAG_03187
BGH : BDBG_01055 BDBG_06928
PNO : SNOG_08645 SNOG_08792 SNOG_10311 SNOG_11599
PTRR : 6338985(PtrM4_028160) 6342873(PtrM4_115470)
BZE : COCCADRAFT_107125 COCCADRAFT_110196 COCCADRAFT_22330 COCCADRAFT_39756
BSC : COCSADRAFT_100696 COCSADRAFT_166933
BOR : COCMIDRAFT_10055 COCMIDRAFT_29064 COCMIDRAFT_89225
AALT : CC77DRAFT_1025005 CC77DRAFT_1092670 CC77DRAFT_949039
ARAB : EKO05_0003849 EKO05_0009234
ZTR : MYCGRDRAFT_108629 MYCGRDRAFT_62699
PFJ : MYCFIDRAFT_210959 MYCFIDRAFT_212492
FFU : CLAFUR5_05841 CLAFUR5_11024
CBET : CB0940_06796 CB0940_08860
BCOM : BAUCODRAFT_302218 BAUCODRAFT_31180
NPA : UCRNP2_10370 UCRNP2_1662 UCRNP2_380 UCRNP2_5007 UCRNP2_9137 UCRNP2_9880
CNE : CNE00330 CNF01770 CNG00410
CNB : CNBE0250 CNBF2940 CNBG4370
CNG : CNAG_02532 CNAG_03562 CNAG_05802
CGI : CGB_E0280W CGB_F4300W CGB_G6310W
CDEU : CNBG_1742 CNBG_2060 CNBG_4227
KMG : 30160429(I203_104438) 30163805(I203_103015) 30168292(I203_105081)
KNE : 92180467(IAR55_003209) 92182003(IAR55_004745) 92184114(IAR55_006856)
TASA : A1Q1_01063 A1Q1_03993
CCAC : CcaHIS019_0104690(CcaverHIS019_0104690) CcaHIS019_0113470(CcaverHIS019_0113470) CcaHIS019_0304260(CcaverHIS019_0304260) CcaHIS019_0411230(CcaverHIS019_0411230) CcaHIS019_0700260(CcaverHIS019_0700260)
PPL : POSPLDRAFT_101343 POSPLDRAFT_93596
TVS : TRAVEDRAFT_138608 TRAVEDRAFT_51132 TRAVEDRAFT_65970 TRAVEDRAFT_91618
DSQ : DICSQDRAFT_157633 DICSQDRAFT_167952 DICSQDRAFT_48303
PCO : PHACADRAFT_172168 PHACADRAFT_210477 PHACADRAFT_24819 PHACADRAFT_258655
SHS : STEHIDRAFT_127642 STEHIDRAFT_161404 STEHIDRAFT_68352
HIR : HETIRDRAFT_117157 HETIRDRAFT_239418 HETIRDRAFT_307723 HETIRDRAFT_482075
PSQ : PUNSTDRAFT_129561 PUNSTDRAFT_137505 PUNSTDRAFT_44417
ADL : AURDEDRAFT_115921 AURDEDRAFT_161209 AURDEDRAFT_184116 AURDEDRAFT_75112
FME : FOMMEDRAFT_154908 FOMMEDRAFT_161622
GTR : GLOTRDRAFT_122190 GLOTRDRAFT_140139 GLOTRDRAFT_67555
CCI : CC1G_05515 CC1G_15725
ABP : AGABI1DRAFT108801(AGABI1DRAFT_108801) AGABI1DRAFT78624(AGABI1DRAFT_78624)
ABV : AGABI2DRAFT208623(AGABI2DRAFT_208623) AGABI2DRAFT208642(AGABI2DRAFT_208642)
MPR : MPER_01474 MPER_03223 MPER_13168
MRR : Moror_15161 Moror_7126 Moror_7127 Moror_9955
MORE : E1B28_010899 E1B28_010900
SCM : SCHCO_01171504(SCHCODRAFT_01171504) SCHCO_02611538(SCHCODRAFT_02611538) SCHCO_02624620(SCHCODRAFT_02624620) SCHCO_02633490(SCHCODRAFT_02633490) SCHCO_02637823(SCHCODRAFT_02637823)
CPUT : CONPUDRAFT_109547 CONPUDRAFT_115900 CONPUDRAFT_129240
SLA : SERLADRAFT_457084 SERLADRAFT_458189
UMA : UMAG_05703 UMAG_11649
PFP : PFL1_01912 PFL1_02372
SGRA : EX895_002684 EX895_006053
PGR : PGTG_01689 PGTG_18680
RIE : OCT59_003979 OCT59_005359 OCT59_020494
DDI : DDB_G0273291(ddo-2) DDB_G0273783(ddo-1)
PIF : PITG_08110 PITG_08125
PSOJ : PHYSODRAFT_319218 PHYSODRAFT_528544
SPAR : SPRG_03672 SPRG_17080
MUL : MUL_1659(aao_1) MUL_2926(aao)
MMI : MMAR_1462 MMAR_2477(aao_1) MMAR_2801(aao)
MMAE : MMARE11_24000(aao_1) MMARE11_27230(aao)
MLI : MULP_02569(aao) MULP_03134(aao_1)
MSHO : MSHO_37360(aao_1) MSHO_42110(aao_2)
MSTO : MSTO_06630(aao) MSTO_11030
MSIM : MSIM_40750(aao_1) MSIM_50640(aao_2)
MSAK : MSAS_07960(aao_1) MSAS_18330(aao_2)
MBAI : MB901379_02306 MB901379_02594
MHEK : JMUB5695_04488(aao)
MMAM : K3U93_11445 K3U93_12940
NAH : F5544_16655 F5544_20745
NSPU : IFM12276_24090(aao)
SVT : SVTN_31495 SVTN_33545
SCX : AS200_09095 AS200_29990
SLE : sle_10800(sle_10800) sle_33170(sle_33170)
SPUN : BFF78_06535 BFF78_37385
SAST : CD934_03375 CD934_22680
SLIA : HA039_04415 HA039_16210
SPEU : CGZ69_29245 CGZ69_31770
SYUN : MOV08_08870 MOV08_15915
SCOA : QU709_04790 QU709_38385
SINN : ABB07_05055 ABB07_37290
STPB : QR97_18110 QR97_18975
SMIB : SMIR_01015 SMIR_36195
SCT : SCAT_2906 SCAT_4156 SCAT_p0271
SCY : SCATT_28970 SCATT_41430 SCATT_p14710
PSUL : AU252_09265 AU252_13920
NAQU : ENKNEFLB_01867(aao)
NRN : SHK17_04235 SHK17_06825
AMYZ : HUW46_00221(aao_1) HUW46_08167(aao_2)
MICB : MicB006_5064 MicB006_5075
MSAG : GCM10017556_37480 GCM10017556_56640
MCRA : ID554_09900 ID554_09910 ID554_10090 ID554_27215
VER : HUT12_03430 HUT12_13800
MCHL : PVK74_00910 PVK74_00965
MCAY : PVK37_12955 PVK37_23170
AMS : AMIS_14610 AMIS_39880
ACTN : L083_3882 L083_4798(aao) L083_4810
AIH : Aiant_29890(aao_1) Aiant_29900(aao_2)
ACTL : L3i22_058560 L3i22_094770(aao)
ASIC : Q0Z83_029290 Q0Z83_072730
AOU : ACTOB_007053 ACTOB_007446
ACTE : ACTI_35650 ACTI_58700
PLAB : C6361_09360 C6361_27195
PLAT : C6W10_05870 C6W10_25355
PSUU : Psuf_006270 Psuf_039050
DVC : Dvina_05660 Dvina_06075 Dvina_08015
DFU : Dfulv_00805 Dfulv_07435
DROS : Drose_00720 Drose_07775
DAUR : Daura_07455 Daura_28770 Daura_28785
DMAT : Dmats_05555 Dmats_07525
DACT : KZZ52_00815 KZZ52_07310
CCAZ : COUCH_20700 COUCH_34545
SCYS : NIES4073_76230(aao)
» show all
Taxonomy
Reference
Authors
DIXON M, KLEPPE K.
Title
D-AMINO ACID OXIDASE. I. DISSOCIATION AND RECOMBINATION OF THE HOLOENZYME.
Journal
Reference
2
Authors
Dixon M, Kleppe K.
Title
D-Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence.
Journal
Biochim Biophys Acta 96:368-382 (1965)
Reference
Authors
DIXON M, KLEPPE K.
Title
D-AMINO ACID OXIDASE. 3. EFFECT OF PH.
Journal
Reference
Authors
MASSEY V, PALMER G, BENNETT R.
Title
The purification and some properties of D-amino acid oxidase.
Journal
Reference
5
Authors
Meister A, Wellner D.
Title
Flavoprotein amino acid oxidase.
Journal
In: Boyer PD, Lardy H, Myrback K (eds). The Enzymes. 2nd ed. Vol. 7. New York: Academic Press; 1963. p. 609-648.
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.3
ExPASy - ENZYME nomenclature database: 1.4.3.3
BRENDA, the Enzyme Database: 1.4.3.3
LinkDB
All DBs