KEGG   ORTHOLOGY: K00462
Entry
K00462                      KO                                     
Symbol
bphC
Name
biphenyl-2,3-diol 1,2-dioxygenase [EC:1.13.11.39]
Pathway
map00361  Chlorocyclohexane and chlorobenzene degradation
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00361 Chlorocyclohexane and chlorobenzene degradation
    K00462  bphC; biphenyl-2,3-diol 1,2-dioxygenase
   00621 Dioxin degradation
    K00462  bphC; biphenyl-2,3-diol 1,2-dioxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.39  biphenyl-2,3-diol 1,2-dioxygenase
     K00462  bphC; biphenyl-2,3-diol 1,2-dioxygenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K00462
Other DBs
RN: R03462 R05245 R05256 R07827
COG: COG0346
GO: 0018583
Genes
PSD: DSC_09355
BXE: Bxe_C1191(bphC)
BXB: DR64_8614(bphC)
ACK: C380_15945(bphC)
CTES: O987_08235
ABRE: pbN1_20550(bphC)
CAUL: KCG34_11050
GJF: M493_00030(bphC)
PNP: IJ22_06970
SIV: SSIL_3694
RHA: RHA1_ro08055(bphC1)
ROP: ROP_pROB02-01620(bnzC)
CWO: Cwoe_0444
AG: BAC23089(bphC) BAM76241(bphC)
 » show all
Reference
PMID:8428946
  Authors
Eltis LD, Hofmann B, Hecht HJ, Lunsdorf H, Timmis KN
  Title
Purification and crystallization of 2,3-dihydroxybiphenyl 1,2-dioxygenase.
  Journal
J Biol Chem 268:2727-32 (1993)
  Sequence
[bxe:Bxe_C1191]
Reference
  Authors
Vezina J, Barriault D, Sylvestre M
  Title
Family shuffling of soil DNA to change the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase.
  Journal
J Bacteriol 189:779-88 (2007)
DOI:10.1128/JB.01267-06
LinkDB

KEGG   REACTION: R05245
Entry
R05245                      Reaction                               
Name
2,3-Dihydroxy-4'-chlorobiphenyl:oxygen 1,2-oxidoreductase (decyclizing)
Definition
2,3-Dihydroxy-4'-chlorobiphenyl + Oxygen <=> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
Equation
Reaction class
RC01306  C06586_C06587
Enzyme
Pathway
rn00621  Dioxin degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Orthology
K00462  biphenyl-2,3-diol 1,2-dioxygenase [EC:1.13.11.39]
LinkDB

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