KEGG ORTHOLOGY: K00467

ORTHOLOGY: K00467

Entry

K00467                      KO

Symbol

E1.13.12.4

Name

lactate 2-monooxygenase [EC:1.13.12.4]

Pathway

map00620

Pyruvate metabolism

map01100

Metabolic pathways

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K00467  E1.13.12.4; lactate 2-monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.12  With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
    1.13.12.4  lactate 2-monooxygenase
     K00467  E1.13.12.4; lactate 2-monooxygenase

Other DBs

RN:

R00319

COG:

COG1304

GO:

0050040

Genes

LAK:

106155094

QSU:	112002987 112040353

LTH:	KLTH0H16148g

TDL:	TDEL_0A08010(TDEL0A08010)

TGB:	HG536_0E00120 HG536_0G00120

PAN:	PODANSg5965

TTT:	THITE_2113301

MTM:	MYCTH_2137000

MGR:

MGG_16456

PPEI:

PpBr36_05228

TMN:	UCRPA7_7665

SSCK:

SPSK_03321

FGR:	FGSG_03439 FGSG_03984

FPU:	FPSE_05293 FPSE_08362

FVR:	FVEG_10135 FVEG_13676

FOX:	FOXG_11687 FOXG_16560

NHE:	NECHADRAFT_104292 NECHADRAFT_82845

TRE:	TRIREDRAFT_53302

TRR:	M419DRAFT_4620

MAW:

MAC_03786

MAJ:

MAA_04225

CMT:

CCM_06299

PLJ:	VFPFJ_05083

CFJ:	CFIO01_10237

CHIG:

CH63R_00806

PFY:	PFICI_01208 PFICI_08828

SSL:	SS1G_04795

BFU:	BCIN_01g02870

PSCO:

LY89DRAFT_669394 LY89DRAFT_777475

ANI:	AN8587.2 AN8744.2

AFM:	AFUA_1G00500 AFUA_6G02720 AFUA_8G06000

ACT:	ACLA_059400 ACLA_097750

NFI:	NFIA_049040 NFIA_098780

AOR:	AO090003001007 AO090120000165

ANG:	ANI_1_238014(An01g01880) ANI_1_998104(An12g08270)

AFV:	AFLA_000661 AFLA_009385

ALUC:

AKAW2_20378A AKAW2_61174A

ACHE:

ACHE_10449S ACHE_50863A ACHE_60535A

APUU:

APUU_10549A APUU_61297A APUU_61466S

PCS:	Pc22g24130

PDP:	PDIP_26590

TMF:	PMAA_093230

TRG:	TRUGW13939_07118

PNO:	SNOG_07595

PTE:

PTT_11971

BZE:	COCCADRAFT_25134

BSC:	COCSADRAFT_31848

BOR:	COCMIDRAFT_92461

AALT:

CC77DRAFT_402943 CC77DRAFT_949939

ZTR:	MYCGRDRAFT_100239 MYCGRDRAFT_75580

PFJ:	MYCFIDRAFT_216799

FFU:	CLAFUR5_11374

BCOM:

BAUCODRAFT_37000

NPA:	UCRNP2_7524 UCRNP2_8491

SPO:	SPAPB1A11.03

TVS:	TRAVEDRAFT_32144

DSQ:	DICSQDRAFT_141721

PCO:	PHACADRAFT_265499

SHS:	STEHIDRAFT_110458 STEHIDRAFT_122144 STEHIDRAFT_131803

HIR:	HETIRDRAFT_440215(lmo1)

PSQ:	PUNSTDRAFT_41912

ADL:	AURDEDRAFT_111456 AURDEDRAFT_188206

FME:	FOMMEDRAFT_96364

GTR:	GLOTRDRAFT_121815 GLOTRDRAFT_139316

LBC:	LACBIDRAFT_230911

MRR:	Moror_11589

E1B28_012807

CCI:	CC1G_03412

SCM:	SCHCODRAFT_48810 SCHCODRAFT_80154

ABP:	AGABI1DRAFT106734(AGABI1DRAFT_106734) AGABI1DRAFT128349(AGABI1DRAFT_128349)

ABV:	AGABI2DRAFT119340(AGABI2DRAFT_119340) AGABI2DRAFT179188(AGABI2DRAFT_179188)

CPUT:

CONPUDRAFT_144284 CONPUDRAFT_159793 CONPUDRAFT_159794

SLA:	SERLADRAFT_449858

UMA:	UMAG_12269

PFP:	PFL1_03774

MGL:

MGL_4274

MRT:	MRET_3385 MRET_3388

NAX:	HC341_07450

SALN:

ATER:

BBAE:

MESP:

MESO:

NIY:	FQ775_18610

BVZ:	BRAD3257_1893

BBAR:

RHAL1_01593

PSTG:

E8M01_02990

CCR:

CC_1396

CCS:	CCNA_01462

CHQ:	AQ619_13805

CAUF:

CSW63_13370

BGOE:

IFJ75_03175

TSV:	DSM104635_01034

CBOT:

ATE48_15170

SGI:	SGRAN_1891

SPHO:

C3E99_09600

STAX:

MC45_12445

SNJ:	A7E77_08850

SMY:	BJP26_04730

SPHF:

SPAI:

SARI:

SSUA:

SPZR:

POQ:	KZX46_02625

AEP:	AMC99_02085

EFV:	CHH26_10045

ELQ:	Ga0102493_111935

ERK:	CD351_13195

ERF:	FIU90_13055

PNS:	A9D12_00870

PORL:

BG023_112498

PHZ:	CHX26_13775

POT:	E2E27_08390

BAO:	BAMF_2066(lldA)

BAZ:	BAMTA208_07170(lldA)

BQL:

LL3_02170

BXH:	BAXH7_01458

BACO:

OXB_1571

BFD:	NCTC4823_01446

BBAD:

K7T73_19440

BHK:	B4U37_21375

BCOH:

BC6307_00055 BC6307_20065

BKW:	BkAM31D_07910

BON:	A361_02260

BKO:	CKF48_06915

CGOT:

J1899_19100

OCN:	CUC15_16050

LSP:

Bsph_0911

LFU:	HR49_21515

LYS:	LBYS11_02320

LYB:	C3943_02925

LYG:	C1N55_10570

LPAK:

GDS87_02415

LAGR:

FJQ98_02770

LMAC:

I6G82_16085

HHD:	HBHAL_5002

HMN:	HM131_02380

TAP:	GZ22_00630

TAID:

KS242_01890

VIR:	X953_19540

VHL:	BME96_18650

VIM:	GWK91_05300

PSYH:

D0S48_03290 D0S48_10995

PSYO:

PB01_07965

GRC:	GI584_08935

RUE:	DT065_15660

SALE:

EPH95_15575

SCIB:

HUG20_03980

SCIA:

HUG15_05180

BVQ:	FHE72_19350

GAJ:	MY490_12440

BBE:	BBR47_10990

BFM:	BP422_00845

BAGR:

BA6348_23275

BCHS:

JNE38_05790

PNP:	IJ22_14970

PKB:	B4V02_21435

PLYC:

GXP70_16545

AAC:

Aaci_0905

AAD:	TC41_0915(lldD)

ACUR:

PMAR:

SPSY:

SPAE:

NTR:	B0W44_09070

KPUL:

GXN76_05410

KEB:	GXN75_12685

CPRO:

CPRO_00360(lldD)

THEP:

DYI95_006990

MPA:	MAP_2959c MAP_3486

MAO:	MAP4_0291 MAP4_0845

MAVI:

RC58_01375 RC58_04155

MAVU:

RE97_01385 RE97_04155

MAV:	MAV_3747 MAV_4345

MIT:	OCO_35830 OCO_42100

MIA:	OCU_35880 OCU_42020

MID:	MIP_05418 MIP_06345

MYO:	OEM_36440 OEM_42450

MCHI:

AN480_18940 AN480_22085

MIR:	OCQ_37050 OCQ_43370

MMAL:

CKJ54_16950 CKJ54_20120

MLP:

MLM_2976

MMAN:

MMAN_02010 MMAN_30200

MSA:	Mycsm_02356 Mycsm_04358

MMC:

Mmcs_1989

MKM:

Mkms_2035

MJL:

Mjls_1969

MMI:	MMAR_1816(lldD1_1)

MMAE:

MMARE11_17430(lldD1_1)

MMM:	W7S_17900 W7S_21070

MLI:	MULP_01974(lldD1_1)

MKN:	MKAN_20375 MKAN_24315

MYV:	G155_11870

MYE:	AB431_22605

MGO:	AFA91_20360 AFA91_26970

MHAD:

B586_03080

MDX:	BTO20_22945

MSHG:

MSG_01679

MFJ:	MFLOJ_16240

MSTO:

MSTO_17740

MSIM:

MSIM_06990 MSIM_46600

MSAK:

MSAS_53980

MKU:	I2456_01065 I2456_09140

MGRO:

FZ046_07485 FZ046_16250

MXE:	MYXE_32880

MNV:	MNVI_13100 MNVI_32110

MPAG:

C0J29_10565

MNM:	MNVM_34320

MGOR:

MCOO:

MBAI:

MSEO:

MPSE:

MSHO:

MHEK:

MGAU:

MBRD:

MBRA_19040 MBRA_47500

MKR:	MKOR_16820

MDF:	K0O62_11390

MMAM:

MHOL:

MHER:

MSEN:

MPAE:

MOT:	LTS72_15725

MVM:	MJO54_14915

MRF:	MJO55_09985

MPAA:

MKK62_16125

MCRO:

MI149_22575

MSM:	MSMEG_2512 MSMEG_3962

MSG:	MSMEI_2453 MSMEI_3870

MSB:	LJ00_12505 LJ00_19690

MSN:	LI99_12505 LI99_19695

MSH:	LI98_12510 LI98_19700

MVA:

Mvan_2206

MGI:

Mflv_4136

MSP:	Mspyr1_34790

MCB:	Mycch_1962 Mycch_5226

MNE:	D174_11200

MYN:	MyAD_10985

MFT:	XA26_24420

MPHL:

MPHLCCUG_02156 MPHLCCUG_03229

MVQ:

MYVA_2110

MLL:	B1R94_07495

MRH:	MycrhN_5780

MTHN:

4412656_01635

MHAS:

MHAS_00210 MHAS_02543

MDU:	MDUV_22960

MCHT:

MCHIJ_27650

MDR:	MDOR_13790

MAUU:

NCTC10437_02058

MMAG:

MMAD_21890

MMOR:

MMOR_42480

MFX:	MFAL_39590

MAIC:

MAIC_40150

MIJ:	MINS_36830

MALV:

MALV_14880

MTY:	MTOK_01750

MPSC:

MPSYJ_44590

MARZ:

MARA_18350 MARA_41370(lctB)

MGAD:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_20375

MSEI:

MFLV:

MCEE:

MAB:

MMV:	MYCMA_1114

MABB:

MASS_2049

MABL:

MMASJCM_2075

MCHE:

BB28_10665

MIZ:	BAB75_11395

MSTE:

MSTE_02060

MSAO:

MYCSP_09070

MSAL:

DSM43276_01841

MJD:	JDM601_2615(lldD1_1)

MTER:

4434518_02563(lldD1_1)

MMIN:

MHIB:

ASD:

MPAK:

CVA:	CVAR_1459(lldA)

CTER:

A606_05680

CGY:	CGLY_08565

CCYC:

SCMU_04630

NFA:

NFA_2230

NFR:	ERS450000_04015

NCY:	NOCYR_0180

NBR:	O3I_025715

NNO:	NONO_c21530

NSL:	BOX37_23865

NSR:	NS506_00840 NS506_04199

NTP:	CRH09_01015

NOZ:	DMB37_05110

NOD:	FOH10_10575 FOH10_30525

NAH:	F5544_01080

NAD:	NCTC11293_05745

NWL:	NWFMUON74_01680

NIE:	KV110_00925 KV110_22270 KV110_25410

NTC:	KHQ06_06990

NHU:	H0264_02265 H0264_30695 H0264_36405

NYA:	LTV02_29740 LTV02_30520

NGP:	LTT66_13810 LTT66_28285

RHA:	RHA1_ro05214

RER:

RER_02640

REY:

O5Y_01305

REB:	XU06_01345 XU06_29405

RQI:	C1M55_01325

ROP:

ROP_52640

ROA:	Pd630_LPD01739

REQ:

REQ_15040

RPY:	Y013_03270

RBY:	CEJ39_14010

RHB:

NY08_3449

RFA:	A3L23_01610

RHS:	A3Q41_01746

RHW:	BFN03_00855

RRZ:	CS378_21680

RHU:	A3Q40_03612

RHQ:	IM25_17215

RHOD:

AOT96_11905

RRT:	4535765_02427

RCR:	NCTC10994_00722

RTM:	G4H71_12930

RKO:	JWS14_28565

RGO:	KYT97_20895

GBR:

Gbro_4523

GPO:	GPOL_c05270

GOR:

KTR9_4459

GOQ:	ACH46_19670

GTA:	BCM27_23440

GOC:	CXX93_03955

GIT:	C6V83_00820

GRU:	GCWB2_22440

GOM:	D7316_03007

GAV:	C5O27_05985

GOD:	GKZ92_21420

GAM:	GII34_01635

GJI:	H1R19_21580

GOI:	LK459_10770

GHN:	MVF96_22220

GAMI:

IHQ52_05465

SPIN:

KV203_01105

TPR:

Tpau_2282

TSM:	ASU32_12395

DTM:	BJL86_0920

DIT:	C3V38_00770

DIZ:	CT688_10955

DPC:	A6048_11480

DLU:	A6035_10620

TOY:	FO059_15810

SCO:	SCO0763(SCF81.22)

SMA:	SAVERM_7482(lldA)

SCB:

SCAB_8821

SVL:	Strvi_4645 Strvi_8701

SHY:

SHJG_8102

SHO:	SHJGH_7864

SRC:	M271_28160

SMAL:

SMALA_3394 SMALA_4952

SSOI:

I1A49_20760

SCT:

SCAT_0021

SCY:	SCATT_00230

SBH:

SBI_05614

SVE:

SVEN_0183

SDV:	BN159_1048

SALS:

SLNWT_3990

SCI:	B446_32605

SALU:

DC74_388

SALL:

SAZ_02415

SLV:	SLIV_34115

SGU:	SGLAU_30020(lldA)

STRE:

GZL_08894

SCW:	TU94_31440

SLC:	SL103_22100

STRC:

AA958_28090

SAMB:

SAM23877_6765

SCX:	AS200_06200

SRW:	TUE45_00333

STRF:

ASR50_32450

SLE:	sle_05290(sle_05290)

SPAV:

Spa2297_29895

STRT:

A8713_29410

SGS:	AVL59_17545 AVL59_25835

STSI:

A4E84_37790

SALW:

CP975_00250

SGM:	GCM10017557_07720

SCAD:

DN051_06020

SLS:	SLINC_7725

SNR:	SNOUR_40435

STRD:

NI25_02475

SAUO:

BV401_20455 BV401_28520

SSIA:

SPUN:

SLAU:

SALF:

STRO:

SFK:

SNZ:	DC008_31480

SGE:	DWG14_00937

SRJ:

SRO_4269

SDX:	C4B68_01180 C4B68_03190

SGD:	ELQ87_02855

SCYA:

EJ357_03205

SAST:

CD934_32020

SKA:	CP970_37915

SHAW:

CEB94_37920

SRK:	FGW37_00555

SFIC:

EIZ62_29170

SGAL:

CP966_32740

SFY:	GFH48_05230

SAQU:

EJC51_41510

SGF:	HEP81_04438

SSEO:

SRIM:

SPHV:

SCIN:

SFUG:

SPAC:

STSU:

SCHA:

SCOE:

SBAT:

SSPB:

SPLA:

SBRO:

GQF42_01295 GQF42_35715 GQF42_39355

STUI:

SCHF:

SCYG:

SFEU:

SDW:	K7C20_32440

SAUH:

SMOB:

SPRA:

SROI:

SXN:	IAG42_03880

SHK:	J2N69_04490 J2N69_28875

SANU:

K7396_04645

SACT:

DMT42_34920

SINE:

KI385_38290

SLF:	JEQ17_06575

SDEC:

L3078_41225

KIT:	CFP65_5988

STRI:

C7M71_024050

LEIF:

HF024_07050

LSE:	F1C12_06215

MPRT:

ET475_04200

AGY:	ATC03_00620

AGF:	ET445_03105

CPHY:

B5808_00200

HUM:	DVJ78_02310

HUW:	FPZ11_13795

LYD:	D7I47_12495

ACIT:

HPK19_06905

LMOI:

VV02_23890

YIM:	J5M86_01515

ALX:	LVQ62_06010

XCE:

Xcel_1699

XYL:	ET495_04965

XYA:	ET471_14510

ICA:	Intca_3557

JTE:	ASJ30_00660

JME:	EEW87_013015

TEH:	GKE56_10390

PHW:	G7075_02885

PEI:	H9L10_08525

ORZ:	FNH13_00165

NDK:

I601_3983

NOO:	FE634_12005

NBE:	Back2_29100

NANO:

NARO:

NAQU:

PSIM:

AEZ:	C3E78_15370

AEF:	GEV26_15460

KFL:

Kfla_6271

KQI:	F1D05_16040

NDA:

Ndas_3352

NAL:

B005_0442

NGV:	CDO52_13295

TCU:

Tcur_1619

ACTW:

F7P10_07310

AGRA:

AGRA3207_001596

NOW:	GBF35_37210

FRI:	FraEuI1c_1375

GOB:

Gobs_0453

BSD:	BLASA_0435

MMAR:

MODMU_0520(lldD)

SEN:	SACE_2627(idiB_2) SACE_6523

SACG:

FDZ84_30675

SVI:	Svir_13410

SACC:

AMD:

AMN:

AMM:

AMZ:

AOI:	AORI_1744(lldD)

AJA:	AJAP_30775

AMQ:	AMETH_5351

AMYC:

CU254_37755

AMYB:

BKN51_00925

AAB:	A4R43_19070

AMYY:

AORI:

AACD:

PSEA:

PSEE:

PSEH:

PSEQ:

PECQ:

PAUT:

PBRO:

APRE:

AMI:

SESP:

SSYI:

KAL:

KPHY:

LED:	BBK82_05460

ALO:

PMAD:

SACE:

MTEM:

ASE:

AMS:	AMIS_24980

ACTN:

L083_4402

ACTS:

ACWT_1852

AIH:	Aiant_63170

ATL:	Athai_65440

ASER:

Asera_09780

DVC:	Dvina_35305

CAI:

Caci_4408

SNA:

Snas_2374

NAV:	JQS30_12705

AEY:	CDG81_11185

RXY:

Rxyl_1052

RRD:	RradSPS_0932

AQZ:	KSP35_21630

DGE:

Dgeo_0626

DMR:	Deima_0416

DSW:	QR90_04690

DEZ:	DKM44_01910

DEIN:

DAAJ005_07855

TTH:

TT_C1744

TTS:	Ththe16_0143

TTL:	TtJL18_0155

THC:	TCCBUS3UF1_20520

TOS:	Theos_1524

TAQ:

TO73_0130

TBC:	A0O31_00937

GGR:	HKW67_00060

GBA:

J421_2178

RMR:

Rmar_1466

RMG:	Rhom172_1523

RBAR:

AWN76_008385

HHY:	Halhy_0614

SPIK:

EXU85_17030

RSI:	Runsl_4987

RUN:	DR864_05785

RUP:	DTQ70_07420

CHK:	D4L85_14435

SALR:

HAAD:

HALX:

NPH:

NMO:

NHO:	HWV23_04385 HWV23_10120

NSAL:

HWV07_03610 HWV07_13570

HALI:

BV210_14655

HSN:	DV733_02330

HDO:	MUK72_08850

HWA:

HWC:

HAZZ:

SRUB:

HALG:

HTU:

HDA:	BB347_09095

HSAL:

JMJ58_13915

HLO:	J0X27_01030

HAKZ:

J0X25_01180

NAY:	HYG81_05870

HALY:

HYG82_07630

HRU:	Halru_0473

SALI:

L593_03975

HLR:	HALLA_15205

HLC:	CHINAEXTREME02330

NAJ:	B1756_05245

PTO:

PTO1012

FAC:	FACI_IFERC01G0179

FAI:

FAD_1093

CDIV:

CPM_1628

» show all

Reference

PMID:2324094

Authors

Giegel DA, Williams CH Jr, Massey V

Title

L-lactate 2-monooxygenase from Mycobacterium smegmatis. Cloning, nucleotide sequence, and primary structure homology within an enzyme family.

Journal

J Biol Chem 265:6626-32 (1990)

Sequence

[msm:MSMEG_3962]

LinkDB

DBGET integrated database retrieval system