KEGG   ORTHOLOGY: K00483
Entry
K00483                      KO                                     
Symbol
hpaB
Name
4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9]
Pathway
map00350  Tyrosine metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K00483  hpaB; 4-hydroxyphenylacetate 3-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.9  4-hydroxyphenylacetate 3-monooxygenase
     K00483  hpaB; 4-hydroxyphenylacetate 3-monooxygenase
Other DBs
RN: R02698 R03299
COG: COG2368
GO: 0052881
Genes
EOI: ECO111_5206(hpaB)
EOJ: ECO26_5549(hpaB)
EOH: ECO103_5128(hpaB)
ECOO: ECRM13514_5600
ECOH: ECRM13516_5313
ECOA: APECO78_02880
ECX: EcHS_A4576(hpaB)
ECY: ECSE_4621
ECR: ECIAI1_4567(hpaB)
EUM: ECUMN_4966(hpaB)
EBR: ECB_04222(hpaB)
EBL: ECD_04222(hpaB)
EBE: B21_04188(hpaB)
EBD: ECBD_3674
EKF: KO11_23365(hpaB)
ELW: ECW_m4705(hpaB)
ELL: WFL_22920(hpaB)
EFE: EFER_3070(hpaB)
STY: STY1131(hpaB)
STT: t1820(hpaB)
STM: STM1099(hpaB)
SEO: STM14_1247(hpaB)
SEY: SL1344_1038(hpaB)
SEJ: STMUK_1068(hpaB)
SEB: STM474_1091(hpaB)
SEF: UMN798_1140(hpaB)
SENR: STMDT2_10351(hpaB)
SEND: DT104_10811(hpaB)
SENI: CY43_05615
SPT: SPA1751(hpaB)
SEK: SSPA1627
SEI: SPC_2651(hpaB)
SEC: SCH_1049(hpaB)
SEH: SeHA_C1209(hpaB)
SHB: SU5_01730
SEE: SNSL254_A1194(hpaB)
SEW: SeSA_A1163(hpaB)
SEA: SeAg_B1058(hpaB)
SENS: Q786_04910
SED: SeD_A1174(hpaB)
SEG: SG0988(hpaB)
SEL: SPUL_1958(hpaB)
SEGA: SPUCDC_1944(hpaB)
SET: SEN0963(hpaB)
SENA: AU38_04970
SENO: AU37_04960
SENV: AU39_04960
SENQ: AU40_05575
SENL: IY59_05060
SEEP: I137_08900
SENE: IA1_05410
SBG: SBG_0945(hpaB)
SBZ: A464_1038
SALZ: EOS98_14120(hpaB)
SFN: SFy_6275
SFS: SFyv_6346
SFT: NCTC1_04750(hpaB_1)
SSN: SSON_4489(hpaB)
SBO: SBO_4404(hpaB)
SBC: SbBS512_E4882(hpaB)
ENC: ECL_00750(hpaB)
ECLX: LI66_03020
ECLY: LI62_03490
ECLZ: LI64_02995
ECLO: ENC_44640
EEC: EcWSU1_00548(hpaB)
ECAN: CWI88_19295(hpaB)
ECHG: FY206_03530(hpaB)
ESH: C1N69_02860(hpaB)
LNI: CWR52_09245(hpaB)
EBG: FAI37_03685(hpaB)
ENZ: G0034_02890(hpaB)
ENS: HWQ15_11430(hpaB)
ENK: LOC22_13770(hpaB)
KPN: KPN_04780(hpaB)
KPU: KP1_0734(hpaB)
KPP: A79E_4372
KPT: VK055_2659(hpaB)
KPJ: N559_4516
KPX: PMK1_02239(hpaB)
KPNU: LI86_23210
KPNK: BN49_4414(hpaB)
KVA: Kvar_4472
KOX: KOX_10015
KOE: A225_0705
EAE: EAE_10315
EAR: CCG31932
KQV: B8P98_24240(hpaB)
KLW: DA718_24790(hpaB)
KAR: LGL98_21845(hpaB)
RAO: DSD31_22280(hpaB)
RTG: NCTC13098_06430(hpaB_2)
REE: electrica_04380(hpaB)
CBRA: A6J81_18505(hpaB)
EBT: EBL_c34040(hpaB)
KIE: NCTC12125_02693(hpaB_1) NCTC12125_02694(hpaB_2)
LEI: C2U54_07965(hpaB)
LEH: C3F35_08740(hpaB)
LEE: DVA44_20850(hpaB)
LER: GNG29_03170(hpaB)
LEA: GNG26_02765(hpaB)
BUF: D8682_01795(hpaB)
YRE: HEC60_20785(hpaB)
IZH: FEM41_12670(hpaB)
PSGC: G163CM_29820(hpaB)
EBF: D782_3927
EBU: CUC76_12085(hpaB)
YPE: YPO1769(hpaB)
YPK: y2539(hpaB)
YPH: YPC_2512(hpaB)
YPA: YPA_1141
YPN: YPN_2354
YPM: YP_1624(hpaB)
YPG: YpAngola_A1640(hpaB)
YPZ: YPZ3_1949(hpaB)
YPD: YPD4_1567(hpaB)
YPX: YPD8_1987(hpaB)
YPW: CH59_3398(hpaB)
YPJ: CH55_908(hpaB)
YPV: BZ15_1780(hpaB)
YPL: CH46_3354(hpaB)
YPS: YPTB1645(hpaB)
YPO: BZ17_857(hpaB)
YPI: YpsIP31758_2357(hpaB)
YPY: YPK_2453
YPB: YPTS_1769
YPQ: DJ40_578(hpaB)
YPU: BZ21_995(hpaB)
YPR: BZ20_330(hpaB)
YPC: BZ23_1273(hpaB)
YPF: BZ19_1072(hpaB)
SMAR: SM39_4967(hpaB)
SMAC: SMDB11_4710(hpaB)
SPE: Spro_0634
SRL: SOD_c05020(hpaB)
SPLY: Q5A_002640(hpaB)
SMAF: D781_0578
SERF: L085_01150
SERM: CLM71_02800(hpaB)
SQU: E4343_13485(hpaB)
SFJ: SAMEA4384070_0661(hpaB)
SOF: NCTC11214_00922(hpaB)
SURI: J0X03_21035(hpaB)
SRHZ: FO014_07040(hpaB)
EPE: CI789_23845(hpaB)
PAY: PAU_00189(hpaB) PAU_00478 PAU_00910(hpaB)
XBO: XBJ1_3600
XBV: XBW1_1452(hpaB) XBW1_4467
XDO: XDD1_0415 XDD1_1013(hpaB)
PSI: S70_06520
PSX: DR96_1964(hpaB)
PRG: RB151_008030(hpaB)
PALA: CO695_00795(hpaB)
PHEI: NCTC12003_00816(hpaB)
PRQ: CYG50_11520(hpaB)
PRJ: NCTC6933_00873(hpaB)
PVC: G3341_03820(hpaB)
MWI: MNY66_12740(hpaB)
HPAR: AL518_09695(hpaB)
PMU: PM1523
PMV: PMCN06_1790(hpaB)
PMP: Pmu_17900(hpaB)
PMUL: DR93_372(hpaB)
PCAI: K7G93_001658(hpaB)
PAE: PA4091(hpaA)
PAEV: N297_4221(hpaB)
PAEI: N296_4221(hpaB)
PAU: PA14_11000(hpaA)
PAP: PSPA7_1007(hpaB)
PAG: PLES_08851(hpaA)
PAF: PAM18_0849(hpaA)
PNC: NCGM2_5292(hpaA)
PAEB: NCGM1900_0869(hpaA)
PAEP: PA1S_04375
PAEM: U769_04385
PAEL: T223_04325
PAEU: BN889_04541(hpaB)
PAEG: AI22_29240
PAEC: M802_4219(hpaB)
PAEO: M801_4087(hpaB)
PFL: PFL_3356(hpaB)
PPRC: PFLCHA0_c33860(hpaB)
PPRO: PPC_3380(hpaB)
PLUL: FOB45_04640(hpaB)
PSEM: TO66_17310
PSOS: POS17_3333(hpaB)
PDW: BV82_1320
PSEP: C4K39_5324
EMO: DM558_04925(hpaB)
AGU: AS4_29660(nphA1)
SWD: Swoo_2019
CPS: CPS_2047
CZA: CYCME_2117(hpaB)
REH: H16_B0496(h16_B0496)
CNC: CNE_2c04450(hpaH)
BCN: Bcen_4663
BCJ: BCAM0734
BCEN: DM39_4430
BCEO: I35_4633
BCT: GEM_5625
BCED: DM42_4353
BCON: NL30_22200
BLAT: WK25_13940
BSEM: WJ12_23670
BPSL: WS57_10300
BMEC: WJ16_22580
PPNO: DA70_08135
PPNM: LV28_22445
PPUL: RO07_16865
PAPI: SG18_15675
HYF: DTO96_101742(hpaB)
CABA: SBC2_49520(hpaH)
KGY: EHF36_15900(hpaB)
DAC: Daci_3024
MES: Meso_2465
PLA: Plav_1785
RHI: NGR_b20090(hpaB)
SFH: SFHH103_05222(hpaB)
EAD: OV14_a0070(hpaB)
SHZ: shn_16275
BARH: WN72_40660
BVZ: BRAD3257_2210(nphA)
VGO: GJW-30_1_02620(hpaB)
AZC: AZC_4189
SNO: Snov_2630
DEQ: XM25_03690(pvcC)
HDI: HDIA_0239(npcA)
TSO: IZ6_13900
LABT: FIU93_23110(nphA1)
MALU: KU6B_25150
PTP: RCA23_c29330(hpaH)
PALW: PSAL_024270(npcA)
SECH: B18_03560
GXL: H845_1141
KEU: S101446_00275(hpaB)
KSC: CD178_01478(hpaH)
ASZ: ASN_1362(hpaB)
BSU: BSU18620(yoaI)
BSR: I33_2090(hpaB)
BSL: A7A1_2448
BSH: BSU6051_18620(yoaI)
BSUT: BSUB_02002(yoaI)
BSUL: BSUA_02002(yoaI)
BSUS: Q433_11010
BSQ: B657_18620(yoaI)
BSX: C663_1926
BSS: BSUW23_09940(yoaI)
BST: GYO_2242(hpaB)
BAY: RBAM_002630(hpaB)
BAQ: BACAU_0205(yoaI)
BYA: BANAU_0209(yoaI)
BAMP: B938_01060
BQY: MUS_0220(yoaI)
BAML: BAM5036_0217(yoaI)
BAMA: RBAU_0233(yoaI)
BAMN: BASU_0220(yoaI)
BAMB: BAPNAU_0209(yoaI)
BAMT: AJ82_01435
BAMY: V529_02230
BAO: BAMF_0207(yoaI)
BAZ: BAMTA208_01065(yoaI)
BQL: LL3_00211(yoaI)
BAMI: KSO_018345
BAMC: U471_02150
BAMF: U722_01355
BSIA: CWD84_20685(hpaB)
BTEQ: G4P54_10690(hpaB)
BCA: BCE_2601
BTT: HD73_3424
BTHI: BTK_16895
BJS: MY9_2034
BACP: SB24_08490
BACB: OY17_04010
BACY: QF06_08435
BACL: BS34A_20630(yoaI)
BALM: BsLM_1985
BGY: BGLY_3123
BACQ: DOE78_09930(hpaB)
BCIR: C2I06_15050(hpaB)
BMQ: BMQ_2417(hpaB)
BMD: BMD_2382(hpaB)
BMH: BMWSH_2819(pvcC)
BMEG: BG04_4791(hpaB)
PKS: IE339_14145(hpaB)
BHA: BH3836
BCL: ABC0890
CGOT: J1899_15635(hpaB)
OIH: OB2872
OCN: CUC15_07490(hpaB)
GTN: GTNG_2992(hpaB)
GGH: GHH_c22230(yoaI) GHH_c31080(hpaB)
GZA: IC807_06805(hpaB) IC807_11295(hpaB)
PTB: DER53_14690(hpaB)
PCAL: BV455_00235(nphA1) BV455_02281
ANM: GFC28_1574(hpaB) GFC28_3725(hpaB)
AAMY: GFC30_1755(hpaB)
ANL: GFC29_1708(hpaB) GFC29_54(hpaB)
AND: GRQ40_05030(hpaB) GRQ40_12980(hpaB)
LSP: Bsph_3875(pvcC)
LYZ: DCE79_11215(hpaB)
LYG: C1N55_11360(hpaB)
LAGR: FJQ98_19945(hpaB)
LMAC: I6G82_04210(hpaB)
HHD: HBHAL_2383(hpaB) HBHAL_3970(yoaI)
HLI: HLI_17040(hpaB) HLI_19760(hpaB)
TAID: KS242_03225(hpaB)
VIL: CFK37_10560(hpaB) CFK37_10890(hpaB)
VNE: CFK40_05945(hpaB)
VIM: GWK91_09765(hpaB)
VPT: KBP50_11285(hpaB)
PASA: BAOM_2294(hpaB) BAOM_2295(hpaB)
PPSR: I6J18_05330(hpaB)
AQT: FN924_04995(hpaB)
PSYH: D0S48_01905(hpaB) D0S48_11000(hpaB)
PSYO: PB01_01290(hpaB) PB01_10745(hpaB) PB01_19030(hpaB)
PRD: F7984_03855(hpaB)
GRC: GI584_18890(hpaB)
POF: GS400_10225(hpaB)
MEKU: HUW50_04520(hpaB)
MDG: K8L98_21235(hpaB)
BVJ: I5776_09945(hpaB) I5776_15190(hpaB)
BOU: I5818_11355(hpaB) I5818_18885(hpaB)
CTHU: HUR95_08550(hpaB)
PMW: B2K_22570
PLV: ERIC2_c16720(hpaB)
PRI: PRIO_3489
PCHI: PC41400_28695(hpaB)
PBK: Back11_14430(yoaI)
ASOC: CB4_02002(hpaH) CB4_02465
ATHE: K3F53_04820(hpaB)
AAC: Aaci_0339
AAD: TC41_0460(hpaB)
EFF: skT53_05560(yoaI)
SIV: SSIL_0564(yoaI)
SOB: CSE16_08880(hpaB) CSE16_18810(hpaB)
PANC: E2636_09660(hpaB) E2636_17240(hpaB)
VIJ: JNUCC6_17985(hpaB)
LPL: lp_0070
LPJ: JDM1_0079
TMR: Tmar_1818
SAY: TPY_2462(hpaB)
MMC: Mmcs_2617
MKM: Mkms_2661
MJL: Mjls_2646
MSIM: MSIM_36600
MSAK: MSAS_12990
MVA: Mvan_3156
MVQ: MYVA_2937
MHEV: MHEL_41210
CTED: CTEST_09800(nphA1)
CCOE: CETAM_00340(nphA1)
COK: COCCU_02390(nphA1)
NFR: ERS450000_01009(hpaB_1) ERS450000_02023(hpaB_2) ERS450000_05550(hpaB_3)
RER: RER_54270
RHU: A3Q40_03004(nphA1)
RRT: 4535765_04635(hpaB)
GRU: GCWB2_07650(nphA2)
GOM: D7316_01448(nphA1)
SVE: SVEN_5100
SALJ: SMD11_6592(hpaB)
SBAT: G4Z16_05465(hpaB)
SPLA: CP981_35185(hpaB)
ARR: ARUE_c05860(hpaB)
AAU: AAur_0618
BCV: Bcav_0870
PSIM: KR76_24440
AOI: AORI_4289(hpaB)
AJA: AJAP_17445(hpaH)
AMYY: YIM_15275(nphA1)
AORI: SD37_21915
PSEA: WY02_09470
PSEE: FRP1_25220
PSEH: XF36_28690
PAUT: Pdca_13110
SESP: BN6_55630 BN6_58660(sam5)
ACTI: UA75_20985
ACAD: UA74_20490
FLH: EJ997_06155(hpaB)
RXY: Rxyl_1857
CWO: Cwoe_4365
RCA: Rcas_2414
CAU: Caur_1347
CAG: Cagg_2030
STI: Sthe_2805
KBS: EPA93_17875(hpaB)
THUG: KNN16_07250(hpaB)
DRA: DR_A0223
DGE: Dgeo_2418
DWU: DVJ83_13505(hpaB)
DFC: DFI_17460
DEIN: DAAJ005_01865(hpaB)
DPH: EHF33_17480(hpaB)
DRD: LMT64_12510(hpaB)
TRA: Trad_1888
TTH: TT_C0594
TTJ: TTHA0960(TTHA0960) TTHB249(TTHB249)
TSC: TSC_c10450(hpaB)
TAQ: TO73_1002
TANT: KNN15_10285(hpaB)
MRB: Mrub_1332
AFU: AF_0885
STO: STK_07260(pheA1)
SSO: SSO2053(hpaA)
SCAS: SACC_13250
SAI: Saci_2294(hpaA)
SID: M164_0713
SII: LD85_0739
SIH: SiH_0629
SIR: SiRe_0706
SIC: SiL_0742
ACIH: HS5_11710
CSTY: KN1_28510
POG: Pogu_1357
 » show all
Reference
  Authors
Xun L, Sandvik ER
  Title
Characterization of 4-hydroxyphenylacetate 3-hydroxylase (HpaB) of Escherichia coli as a reduced flavin adenine dinucleotide-utilizing monooxygenase.
  Journal
Appl Environ Microbiol 66:481-6 (2000)
DOI:10.1128/AEM.66.2.481-486.2000
  Sequence
[elw:ECW_m4705]
LinkDB

KEGG   ORTHOLOGY: K00484
Entry
K00484                      KO                                     
Symbol
hpaC
Name
flavin reductase (NADH) [EC:1.5.1.36]
Pathway
map00350  Tyrosine metabolism
map00740  Riboflavin metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K00484  hpaC; flavin reductase (NADH)
  09108 Metabolism of cofactors and vitamins
   00740 Riboflavin metabolism
    K00484  hpaC; flavin reductase (NADH)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.36  flavin reductase (NADH)
     K00484  hpaC; flavin reductase (NADH)
Other DBs
RN: R02698 R03299 R05705 R09748 R09750
COG: COG1853
GO: 0036382
Genes
EOI: ECO111_5205(hpaC)
EOJ: ECO26_5548(hpaC)
EOH: ECO103_5127(hpaC)
ECOO: ECRM13514_5599
ECOH: ECRM13516_5312
ECOA: APECO78_02875
ECX: EcHS_A4575(hpaC)
ECY: ECSE_4620
ECR: ECIAI1_4566(hpaC)
EUM: ECUMN_4965(hpaC)
EBR: ECB_04221(hpaC)
EBL: ECD_04221(hpaC)
EBE: B21_04187(ybl221)
EBD: ECBD_3675
EKF: KO11_23360(hpaC)
ELW: ECW_m4704(hpaC)
ELL: WFL_22915(hpaC)
EFE: EFER_3071(hpaC)
STY: STY1130(hpaC)
STT: t1821(hpaC)
STM: STM1098(hpaC)
SEO: STM14_1246(hpaC)
SEY: SL1344_1037(hpaC)
SEJ: STMUK_1067(hpaC)
SEB: STM474_1090(hpaC)
SEF: UMN798_1139(hpaC)
SETU: STU288_01820(hpaC)
SETC: CFSAN001921_11685(hpaC)
SENR: STMDT2_10341(hpaC)
SEND: DT104_10801(hpaC)
SENI: CY43_05610(hpaC)
SEEN: SE451236_11340(hpaC)
SPT: SPA1752(hpaC)
SEK: SSPA1628
SEI: SPC_2652(hpaC)
SEC: SCH_1048(hpaC)
SEH: SeHA_C1208(hpaC)
SHB: SU5_01729
SENH: CFSAN002069_03530(hpaC)
SEEH: SEEH1578_14715(hpaC)
SEE: SNSL254_A1193(hpaC)
SEW: SeSA_A1162(hpaC)
SEA: SeAg_B1057(hpaC)
SENS: Q786_04905(hpaC)
SED: SeD_A1173(hpaC)
SEG: SG0987(hpaC)
SEL: SPUL_1959(hpaC)
SEGA: SPUCDC_1945(hpaC)
SET: SEN0962(hpaC)
SENA: AU38_04965(hpaC)
SENO: AU37_04955(hpaC)
SENV: AU39_04955(hpaC)
SENQ: AU40_05570(hpaC)
SENL: IY59_05055(hpaC)
SENJ: CFSAN001992_06155(hpaC)
SEEC: CFSAN002050_11885(hpaC)
SEEB: SEEB0189_014080(hpaC)
SEEP: I137_08905(hpaC)
SENB: BN855_10530(hpaC)
SENE: IA1_05405(hpaC)
SENC: SEET0819_12150(hpaC)
SBG: SBG_0944(hpaC)
SBZ: A464_1037
SFL: SF4373(hpaC)
SFX: S4643(hpaC)
SFV: SFV_4374(hpaC)
SFE: SFxv_4767
SFN: SFy_6274
SFS: SFyv_6345
SFT: NCTC1_04749(hpaC)
SSN: SSON_4488(hpaC)
SBO: SBO_4403(hpaC)
SBC: SbBS512_E4881(hpaC)
SHQ: A0259_03500(hpaC)
ENC: ECL_00749(hpaC)
ECLE: ECNIH2_03895(hpaC)
ECLN: ECNIH4_19905(hpaC)
ECLI: ECNIH5_03020(hpaC)
ECLX: LI66_03015(hpaC)
ECLY: LI62_03485(hpaC)
ECLZ: LI64_02990(hpaC)
ECLO: ENC_44630
EHM: AB284_21990(hpaC)
ECLA: ECNIH3_03020(hpaC)
ECLC: ECR091_03000(hpaC)
EAU: DI57_15625(hpaC)
EEC: EcWSU1_00546(hpaC)
ECAN: CWI88_19300(hpaC)
ECLS: LI67_003950(hpaC)
ESH: C1N69_02855(hpaC)
ENX: NI40_002860(hpaC)
KPN: KPN_04779(hpaC)
KPU: KP1_0733(hpaC)
KPP: A79E_4373
KPH: KPNIH24_03220(hpaC)
KPZ: KPNIH27_03095(hpaC)
KPV: KPNIH29_03410(hpaC)
KPW: KPNIH30_03370(hpaC)
KPY: KPNIH31_04695(hpaC)
KPG: KPNIH32_03375(hpaC)
KPC: KPNIH10_03200(hpaC)
KPQ: KPR0928_03210(hpaC)
KPT: VK055_2660(hpaC)
KPO: KPN2242_02030(hpaC)
KPR: KPR_0856(hpaC)
KPJ: N559_4517
KPI: D364_24350(hpaC)
KPX: PMK1_02238(hpaC)
KPB: FH42_20415(hpaC)
KPNE: KU54_023375(hpaC)
KPNU: LI86_23215(hpaC)
KPNK: BN49_4415(hpaC)
KVA: Kvar_4473
KPE: KPK_4841(hpaC)
KPK: A593_13950(hpaC)
KOX: KOX_10010(hpaC)
KOE: A225_0704
KOY: J415_27725(hpaC)
KOM: HR38_08735(hpaC)
KOK: KONIH1_03735(hpaC)
KOC: AB185_32455(hpaC)
EAE: EAE_10310(hpaC)
EAR: CCG31933
KQV: B8P98_24245(hpaC)
ROR: RORB6_15570(hpaC)
RON: TE10_05450(hpaC)
RTG: NCTC13098_06431(hpaC)
REE: electrica_04381(hpaC)
CBRA: A6J81_18500(hpaC)
EBT: EBL_c34050(hpaC)
PGE: LG71_25565(hpaC)
KLE: AO703_02885(hpaC)
KGO: CEW81_19470(hpaC)
KIE: NCTC12125_02692(hpaC)
KAS: KATP_35150(hpaC)
LAX: APT61_19370(hpaC)
LEI: C2U54_07960(hpaC)
LEH: C3F35_08745(hpaC)
IZH: FEM41_12675(hpaC)
PSGC: G163CM_29830(hpaC)
EBF: D782_3928
EBU: CUC76_12090(hpaC)
YPE: YPO1770(hpaC)
YPK: y2538
YPH: YPC_2511(hpaC)
YPA: YPA_1142
YPN: YPN_2353
YPM: YP_1623(hpaC)
YPG: YpAngola_A1639(hpaC)
YPZ: YPZ3_1948(hpaC)
YPD: YPD4_1568(hpaC)
YPX: YPD8_1986(hpaC)
YPW: CH59_3397(hpaC)
YPJ: CH55_907(hpaC)
YPV: BZ15_1779(hpaC)
YPL: CH46_3353(hpaC)
YPS: YPTB1646(hpaC)
YPO: BZ17_856(hpaC)
YPI: YpsIP31758_2356(hpaC)
YPY: YPK_2452
YPB: YPTS_1770
YPQ: DJ40_577(hpaC)
YPU: BZ21_996(hpaC)
YPR: BZ20_329(hpaC)
YPC: BZ23_1274(hpaC)
YPF: BZ19_1073(hpaC)
SMAR: SM39_4968(hpaC)
SMAC: SMDB11_4711(hpaC)
SMW: SMWW4_v1c05910(rutF)
SPE: Spro_0635
SRL: SOD_c05030(hpaC)
SRY: M621_02655(hpaC)
SPLY: Q5A_002645(hpaC)
SMAF: D781_0579
SLQ: M495_02520(hpaC)
SERF: L085_01145
SERM: CLM71_02805(hpaC)
SQU: E4343_13480(hpaC)
SFJ: SAMEA4384070_0662(hpaC)
SOF: NCTC11214_00921(hpaC)
SURI: J0X03_21030(hpaC)
SRHZ: FO014_07035(hpaC)
SFO: Z042_16845(hpaC)
EPE: CI789_23840(hpaC)
PLU: plu0974(hpaC)
PLUM: A4R40_04865(hpaC)
PAY: PAU_00909(hpaC)
PTT: VY86_13815(hpaC)
PLUI: CE143_05205(hpaC)
PMR: PMI0246(hpaC)
PMIB: BB2000_0397(hpaC)
PVL: AOB99_03995(hpaC)
PVG: CRN77_18180(hpaC)
PHAU: PH4a_11160(hpaC)
PCOL: F1325_04130(hpaC)
PCIB: F9282_03920(hpaC)
PPEE: I6G31_05375(hpaC)
XBO: XBJ1_3599(ycdH)
XBV: XBW1_1453(hpaC)
XNE: XNC1_0810(ycdH)
XNM: XNC2_0796(ycdH)
XDO: XDD1_1012(hpaC)
XBU: HGO23_05325(hpaC)
PSI: S70_06525
PSX: DR96_1963(hpaC)
PRG: RB151_008020(hpaC)
PALA: CO695_00800(hpaC)
PHEI: NCTC12003_00815(hpaC)
PRQ: CYG50_11525(hpaC)
PRJ: NCTC6933_00872(hpaC)
PVC: G3341_03815(hpaC)
MMK: MU9_1190
MWI: MNY66_12745(hpaC)
HAV: AT03_16965(hpaC)
HPAR: AL518_09690(hpaC)
OPO: DSM2777_08260(hpaC)
HDU: HD_0987(hpaC)
GLE: CJD39_07540(hpaC)
PMU: PM1522
PMV: PMCN06_1789(hpaC)
PMP: Pmu_17890(hpaC)
PMUL: DR93_371(hpaC)
PDAG: 4362423_01844(hpaC)
PSKY: A6B44_09445(hpaC)
PATL: KGI96_10160(hpaC)
PCAI: K7G93_001659(hpaC)
MHT: D648_19650(hpaC)
MHQ: D650_6580(hpaC)
MHAT: B824_19600(hpaC)
MHX: MHH_c28120(hpaC)
MHAE: F382_04765(hpaC)
MHAM: J450_03765(hpaC)
MHAO: J451_05010(hpaC)
MHAL: N220_10895(hpaC)
MHAQ: WC39_03320(hpaC)
MHAY: VK67_03320(hpaC)
MVR: X781_6410
MVE: X875_4960
MANN: GM695_05125(hpaC)
MBOS: ICJ55_09905(hpaC)
MPEG: HV560_05555(hpaC)
APL: APL_1349(hpaC)
APJ: APJL_1367(hpaC)
APA: APP7_1401(hpaC)
AEU: ACEE_11280(hpaC)
AIO: EXH44_07625(hpaC)
ALIG: NCTC10568_01672(hpaC)
BTO: WQG_18690
BTRE: F542_3890
BTRH: F543_4540
BTRA: F544_18490
VVY: VV1574
VNI: VIBNI_B1951(hpaC)
VMI: AL543_16395(hpaC)
PAE: PA4092(hpaC)
PAEV: N297_4222(hpaC)
PAEI: N296_4222(hpaC)
PAU: PA14_10990(hpaC)
PAP: PSPA7_1006(hpaC)
PAG: PLES_08841(hpaC)
PAF: PAM18_0848(hpaC)
PNC: NCGM2_5293(hpaC)
PAEB: NCGM1900_0868(hpaC)
PAEP: PA1S_04370
PAEM: U769_04380
PAEL: T223_04320
PAEU: BN889_04542(hpaC)
PAEG: AI22_29245(hpaC)
PAEC: M802_4220(hpaC)
PAEO: M801_4088(hpaC)
PCQ: PcP3B5_30280(hpaC)
PMUI: G4G71_15220(hpaC)
PFL: PFL_3357(hpaC)
PPRC: PFLCHA0_c33870(hpaC)
PPRO: PPC_3381(hpaC)
PLUL: FOB45_04645(hpaC)
PSEM: TO66_17315
PSOS: POS17_3334(hpaC)
PSIL: PMA3_18105
PUM: HGP31_18295(hpaC)
PSEP: C4K39_5325
EMO: DM558_00740(hpaC) DM558_04920(hpaC)
CJA: CJA_1958
NME: NMB1842
NMP: NMBB_2105
NMH: NMBH4476_1786(hpaC)
NMD: NMBG2136_0375(hpaC)
NMM: NMBM01240149_0343(hpaC)
NMS: NMBM01240355_1776(hpaC)
NMQ: NMBM04240196_1783(hpaC)
NMZ: NMBNZ0533_0480(hpaC)
NMA: NMA0614
NMW: NMAA_0302
NMC: NMC0375
NMN: NMCC_0380
NMT: NMV_2032
NMI: NMO_0320
NGO: NGO_0059
NGK: NGK_0083
NLA: NLA_17890
NWE: SAMEA3174300_1574(hpaC)
NSI: A6J88_13285(hpaC)
NMJ: NM96_07675(hpaC)
NEI: BG910_03730(hpaC)
NEK: CGZ77_01410(hpaC)
NFV: FAH67_11135(hpaC)
NSF: FAH66_10430(hpaC)
NZL: D0T92_00275(hpaC)
NAQ: D0T90_04115(hpaC)
NBL: GJV52_03625(hpaC)
NZO: SAMEA4504057_0425(hpaC)
NCI: NCTC10296_01006(hpaC)
NCZ: NCTC10294_01307(hpaC)
NANI: NCTC12227_02146(hpaC)
NBC: H3L91_01450(hpaC)
NWD: H3L96_01830(hpaC)
NSG: H3L94_11560(hpaC)
NMUS: H7A79_1714(hpaC)
NSC: J7445_01550(hpaC)
NPF: LPB400_10790(hpaC)
NDN: H3L92_00405(hpaC)
NWX: CGZ65_12030(hpaC)
NDU: LVJ88_00455(hpaC)
KKI: KKKWG1_0413(hpaC)
AFF: H3L97_00085(hpaC)
CSTE: H3L98_10765(hpaC)
PTES: JQU52_00055(hpaC)
MCER: MON37_02810(hpaC)
USU: LVJ78_01785(hpaC)
BTE: BTH_II0316(hpaC)
BTQ: BTQ_3610(hpaC)
BTJ: BTJ_4646(hpaC)
BTZ: BTL_5434(hpaC)
BTV: BTHA_4769(hpaC)
BTHE: BTN_5104(hpaC)
BTHM: BTRA_5373(hpaC)
BTHA: DR62_5234
BTHL: BG87_5440(hpaC)
BOK: DM82_6338(hpaC)
BOC: BG90_4336(hpaC)
BCJ: BCAM0638 BCAM2115(hpaC)
BCEN: DM39_4519(hpaC) DM39_4923
BCEW: DM40_5612
BCEO: I35_4534 I35_5997(hpaC)
BAM: Bamb_5345
BMK: DM80_4251 DM80_4266(hpaC)
BMUL: NP80_3634(hpaC) NP80_3647
BCED: DM42_4452(hpaC)
BCON: NL30_22660
BLAT: WK25_18270
BSEM: WJ12_23160
BMEC: WJ16_22180
BANN: JFN94_20700(hpaC)
BGU: KS03_3551(hpaC) KS03_4181
BGO: BM43_5956
BGP: BGL_2c23400(hpaC)
BURK: DM992_28725(hpaC)
BXE: Bxe_B2309
BXB: DR64_4641(hpaC)
BFN: OI25_3713(hpaC)
PARB: CJU94_31905(hpaC)
PHS: C2L64_07300(hpaC) C2L64_36225(hpaC)
PTER: C2L65_07035(hpaC) C2L65_31435(hpaC)
PGP: CUJ91_29455(hpaC)
PGIS: I6I06_03785(hpaC)
PACS: FAZ98_33425(hpaC)
PSPU: NA29_23280
PLG: NCTC10937_03008(hpaC)
HYF: DTO96_101741(hpaC)
CABA: SBC2_51660(hpaC_3) SBC2_82000(hpaC_4)
MXA: MXAN_4827
CCX: COCOR_03296(ycdH)
BARH: WN72_10715
RSP: RSP_3957
SECH: B18_03565
GXL: H845_1140
KEU: S101446_00274(rutF)
KSC: CD178_01477(hpaC)
COQ: D9V35_02155(hpaC)
MPOF: MPOR_09360(hpaC)
NFA: NFA_28410
NFR: ERS450000_01248(hpaC)
RHA: RHA1_ro02847(hpaC)
ROP: ROP_25720(hpaC)
SBH: SBI_09695
AOI: AORI_4210(hpaC)
AMYY: YIM_23115(hpaC)
TTH: TT_C0595
TTJ: TTHA0961(TTHA0961)
TAQ: TO73_1001
MRB: Mrub_1331
 » show all
Reference
  Authors
Galan B, Diaz E, Prieto MA, Garcia JL
  Title
Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: a prototype of a new Flavin:NAD(P)H reductase subfamily.
  Journal
J Bacteriol 182:627-36 (2000)
DOI:10.1128/JB.182.3.627-636.2000
  Sequence
[elw:ECW_m4704]
LinkDB

KEGG   ORTHOLOGY: K16901
Entry
K16901                      KO                                     
Symbol
K16901
Name
anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.8 1.14.14.9]
Pathway
map00350  Tyrosine metabolism
map00380  Tryptophan metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K16901  K16901; anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase
   00380 Tryptophan metabolism
    K16901  K16901; anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.8  anthranilate 3-monooxygenase (FAD)
     K16901  K16901; anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase
    1.14.14.9  4-hydroxyphenylacetate 3-monooxygenase
     K16901  K16901; anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase
Other DBs
RN: R02698 R03299 R09517
GO: 0052881
Genes
BCA: BCE_2148
BCX: BCA_2146
BCF: bcf_10170
BCER: BCK_24265
BCEF: BcrFT9_01682
BTL: BALH_1835
BMYC: DJ92_4629
BTRO: FJR70_09265
BNT: GSN03_10105
GST: HW35_13010
BMQ: BMQ_3596(hpaB)
BMD: BMD_3581(hpaB)
BMEG: BG04_470
GTN: GTNG_3160
PASA: BAOM_0489
MMAG: MMAD_31860
CCYC: SCMU_01870
PDX: Psed_0216
PBRO: HOP40_33130(hpaB) HOP40_33375(hpaB)
 » show all
Reference
  Authors
Liu X, Dong Y, Li X, Ren Y, Li Y, Wang W, Wang L, Feng L
  Title
Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2.
  Journal
Microbiology 156:589-95 (2010)
DOI:10.1099/mic.0.031880-0
  Sequence
[gtn:GTNG_3160]
LinkDB

KEGG   REACTION: R02698
Entry
R02698                      Reaction                               
Name
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Definition
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
Equation
Reaction class
RC00001  C00003_C00004
RC00046  C00642_C01161
Enzyme
Pathway
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K00483  4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9]
K00484  flavin reductase (NADH) [EC:1.5.1.36]
K16901  anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.8 1.14.14.9]
K16902  FAD reductase [NAD(P)H] [EC:1.5.1.45]
K23470  4-hydroxyphenylacetate 3-hydroxylase, reductase component [EC:1.5.1.36]
K23492  4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9]
LinkDB

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