Entry
Symbol
ICMT, STE14
Name
protein-S-isoprenylcysteine O-methyltransferase [EC:
2.1.1.100 ]
Pathway
map00900 Terpenoid backbone biosynthesis
map01110 Biosynthesis of secondary metabolites
Reaction
R04496 S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
K00587 ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase
K00587 ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase
BRITE hierarchy
Other DBs
Genes
» show all
Taxonomy UniProt
Reference
Authors
Sapperstein S, Berkower C, Michaelis S
Title
Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export.
Journal
Sequence
Reference
Authors
Chen Y, McQuade KJ, Guan XJ, Thomason PA, Wert MS, Stock JB, Cox EC
Title
Isoprenylcysteine carboxy methylation is essential for development in Dictyostelium discoideum.
Journal
Sequence
Reference
Authors
Huizinga DH, Omosegbon O, Omery B, Crowell DN
Title
Isoprenylcysteine methylation and demethylation regulate abscisic acid signaling in Arabidopsis.
Journal
Sequence
LinkDB
All DBs