KEGG   ORTHOLOGY: K00746
Entry
K00746                      KO                                     
Symbol
CSGALNACT1_2
Name
chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175]
Pathway
map00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
map01100  Metabolic pathways
Module
M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
Reaction
R05929  
Disease
H02551  Skeletal dysplasia with joint laxity and advanced bone age
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.174  glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase
     K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
    2.4.1.175  glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
     K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Other DBs
GO: 0047237 0047238
CAZy: GT7
Genes
HSA: 55454(CSGALNACT2) 55790(CSGALNACT1)
PTR: 450416 464030
PPS: 100987599(CSGALNACT1) 100994377(CSGALNACT2)
GGO: 101151962 101154228
PON: 100172853(CSGALNACT2) 100442293(CSGALNACT1)
PPYG: 129042717 129045307
NLE: 100583001(CSGALNACT1) 100602432(CSGALNACT2)
HMH: 116461304(CSGALNACT2) 116473758(CSGALNACT1)
SSYN: 129480840 129486436
MCC: 703703(CSGALNACT2) 704901(CSGALNACT1)
MCF: 102136560
MNI: 105482127(CSGALNACT1) 105486613(CSGALNACT2)
CSAB: 103215414(CSGALNACT1) 103215756(CSGALNACT2)
CATY: 105571571(CSGALNACT2) 105579259(CSGALNACT1)
PANU: 101012979(CSGALNACT1) 101019767(CSGALNACT2)
TGE: 112630090(CSGALNACT1) 112632117(CSGALNACT2)
MLEU: 105534463(CSGALNACT2) 105539379(CSGALNACT1)
RRO: 104653929(CSGALNACT2) 104662459(CSGALNACT1)
RBB: 108513317(CSGALNACT2) 108526479(CSGALNACT1)
TFN: 117082810(CSGALNACT2) 117092780(CSGALNACT1)
PTEH: 111531316(CSGALNACT2) 111545662(CSGALNACT1)
CANG: 105510156(CSGALNACT1) 105520188(CSGALNACT2)
CJC: 100399122(CSGALNACT2) 100407007(CSGALNACT1)
SBQ: 101027448(CSGALNACT2) 101048885(CSGALNACT1)
CIMI: 108296689(CSGALNACT2) 108312008(CSGALNACT1)
ANAN: 105705382(CSGALNACT1) 105734323(CSGALNACT2)
CSYR: 103268660(CSGALNACT2) 103276583(CSGALNACT1)
MMUR: 105879006(CSGALNACT2) 105882547(CSGALNACT1)
LCAT: 123626380(CSGALNACT1) 123649892(CSGALNACT2)
PCOQ: 105818036 105825209(CSGALNACT1)
OGA: 100942846(CSGALNACT2) 100948840(CSGALNACT1)
MMU: 234356(Csgalnact1) 78752(Csgalnact2)
MCAL: 110295750(Csgalnact2) 110300279(Csgalnact1)
MPAH: 110315909(Csgalnact2) 110336490(Csgalnact1)
RNO: 297554(Csgalnact2) 306375(Csgalnact1)
MCOC: 116069408(Csgalnact1) 116099473(Csgalnact2)
ANU: 117715225(Csgalnact2) 117722009(Csgalnact1)
MUN: 110549131(Csgalnact1) 110558018(Csgalnact2)
CGE: 100754969(Csgalnact1) 100770830(Csgalnact2)
MAUA: 101825715(Csgalnact2) 101840817(Csgalnact1)
PROB: 127216397 127220204(Csgalnact1) 127236114(Csgalnact2)
PLEU: 114689661(Csgalnact2) 114703120(Csgalnact1)
MORG: 121439905(Csgalnact2) 121462726(Csgalnact1)
AAMP: 119807926(Csgalnact2) 119812027(Csgalnact1)
NGI: 103733802(Csgalnact2) 103747604(Csgalnact1)
HGL: 101700905(Csgalnact1) 101719048(Csgalnact2)
CPOC: 100725703(Csgalnact1) 100735627(Csgalnact2)
CCAN: 109688882(Csgalnact1) 109698852(Csgalnact2)
DORD: 105992963(Csgalnact1) 105998871(Csgalnact2)
DSP: 122122368(Csgalnact2) 122125664(Csgalnact1)
PLOP: 125339260(Csgalnact1) 125346567(Csgalnact2)
MMMA: 107153395(Csgalnact2) 107153954(Csgalnact1)
OPI: 101526745(CSGALNACT1) 101533692(CSGALNACT2)
TUP: 102468989(CSGALNACT2) 102490797(CSGALNACT1)
GVR: 103603622(CSGALNACT1) 103605928(CSGALNACT2) 103607542
CFA: 482831(CSGALNACT1) 486786(CSGALNACT2)
CLUD: 112659138(CSGALNACT1) 112672018(CSGALNACT2)
VVP: 112913575(CSGALNACT2) 112916171(CSGALNACT1)
VLG: 121484927(CSGALNACT2) 121489366(CSGALNACT1)
NPO: 129515892(CSGALNACT1) 129520737 129522808(CSGALNACT2)
AML: 100468746(CSGALNACT1) 100484755(CSGALNACT2)
UMR: 103667936(CSGALNACT2) 103677036(CSGALNACT1)
UAH: 113243134(CSGALNACT2) 113245577(CSGALNACT1)
UAR: 123780323(CSGALNACT1) 123800371(CSGALNACT2)
MPUF: 101683049(CSGALNACT2) 101693101(CSGALNACT1)
MNP: 132006455(CSGALNACT1) 132016599(CSGALNACT2)
MLK: 131820662(CSGALNACT1) 131828681(CSGALNACT2)
NVS: 122889841(CSGALNACT1) 122900897(CSGALNACT2)
ORO: 101369554(CSGALNACT2) 101377082(CSGALNACT1)
EJU: 114205257(CSGALNACT2) 114224798(CSGALNACT1)
ZCA: 113919765(CSGALNACT2) 113924441(CSGALNACT1)
MLX: 118009903(CSGALNACT1) 118023420(CSGALNACT2)
NSU: 110573168(CSGALNACT1) 110589538(CSGALNACT2)
LWW: 102726550(CSGALNACT2) 102735074(CSGALNACT1)
FCA: 101096311(CSGALNACT1) 101100841(CSGALNACT2)
PYU: 121036967(CSGALNACT2) 121045298(CSGALNACT1)
PCOO: 112854603(CSGALNACT2) 112858443(CSGALNACT1)
PBG: 122472766(CSGALNACT1) 122493001(CSGALNACT2)
PVIV: 125147674(CSGALNACT2) 125164151(CSGALNACT1)
PTG: 102956824(CSGALNACT1) 102966347(CSGALNACT2)
PPAD: 109262244(CSGALNACT1) 109264614(CSGALNACT2)
HHV: 120234018(CSGALNACT1) 120249250(CSGALNACT2)
BTA: 509328(CSGALNACT2) 528057(CSGALNACT1)
BOM: 102266543(CSGALNACT1) 102285203(CSGALNACT2)
BIU: 109553356(CSGALNACT1) 109553754(CSGALNACT2)
BBIS: 104993236(CSGALNACT1) 104997317(CSGALNACT2)
CHX: 102179349(CSGALNACT1) 102185714(CSGALNACT2)
OAS: 101118243(CSGALNACT2) 101120469(CSGALNACT1)
BTAX: 128048892(CSGALNACT2) 128068254(CSGALNACT1)
MBEZ: 129549446(CSGALNACT1) 129555825(CSGALNACT2)
SSC: 100157878(CSGALNACT2) 100517735 102166124(CSGALNACT1)
CFR: 102513810(CSGALNACT1) 102514190(CSGALNACT2)
CBAI: 105071120(CSGALNACT1) 105072700(CSGALNACT2)
CDK: 105086444(CSGALNACT1) 105092509(CSGALNACT2)
VPC: 102525594(CSGALNACT1) 102542681(CSGALNACT2)
BACU: 103007226(CSGALNACT2) 103010484(CSGALNACT1)
BMUS: 118882632(CSGALNACT2) 118887822(CSGALNACT1)
LVE: 103069443(CSGALNACT2) 103084873(CSGALNACT1)
OOR: 101288535(CSGALNACT2) 101289782(CSGALNACT1)
DLE: 111163996(CSGALNACT2) 111173568(CSGALNACT1)
PCAD: 102982515(CSGALNACT1) 102984892(CSGALNACT2)
PSIU: 116741260(CSGALNACT2) 116746869(CSGALNACT1)
NASI: 112403826(CSGALNACT2) 112413251(CSGALNACT1)
ECB: 100050200(CSGALNACT2) 100052192(CSGALNACT1)
EPZ: 103550620(CSGALNACT2)
EAI: 106824857(CSGALNACT1) 106831340(CSGALNACT2)
MYB: 102244364(CSGALNACT1) 102262652(CSGALNACT2)
MYD: 102764495(CSGALNACT2) 102768920(CSGALNACT1)
MMYO: 118651294(CSGALNACT1) 118670214(CSGALNACT2)
MLF: 102435977(CSGALNACT1) 102443242(CSGALNACT2)
PKL: 118719057(CSGALNACT2) 118730871(CSGALNACT1)
EFUS: 103288197(CSGALNACT1) 103292851(CSGALNACT2)
MNA: 107523899(CSGALNACT1) 107532565(CSGALNACT2)
DRO: 112305453(CSGALNACT2) 112321495(CSGALNACT1)
SHON: 118981053(CSGALNACT2) 118984282(CSGALNACT1)
AJM: 119035897(CSGALNACT2) 119060903(CSGALNACT1)
PDIC: 114497160(CSGALNACT2) 114508884(CSGALNACT1)
PHAS: 123807620(CSGALNACT1) 123820932(CSGALNACT2)
MMF: 118622397 118622545 118632143(CSGALNACT2)
PPAM: 129064775(CSGALNACT1) 129073177(CSGALNACT2)
HAI: 109386291(CSGALNACT1) 109395550(CSGALNACT2)
RFQ: 117021457(CSGALNACT1) 117036051(CSGALNACT2)
PALE: 102878385(CSGALNACT2) 102889741(CSGALNACT1)
PGIG: 120594629(CSGALNACT2) 120613141(CSGALNACT1)
PVP: 105300712(CSGALNACT1) 105309192(CSGALNACT2)
RAY: 107501339(CSGALNACT1) 107517640(CSGALNACT2)
MJV: 108403396(CSGALNACT1) 108408000(CSGALNACT2)
TOD: 119233514(CSGALNACT2) 119257867(CSGALNACT1)
SARA: 101539058 101551713(CSGALNACT1) 101556437(CSGALNACT2)
SETR: 125995073(CSGALNACT2) 126006427(CSGALNACT1)
LAV: 100654033(CSGALNACT1) 100661660(CSGALNACT2)
ETF: 101651335(CSGALNACT2) 101660160(CSGALNACT1)
DNM: 101413578(CSGALNACT2) 101443515(CSGALNACT1)
MDO: 100012272(CSGALNACT2) 100030310(CSGALNACT1)
GAS: 123234841(CSGALNACT1) 123236401(CSGALNACT2)
SHR: 100925396(CSGALNACT1) 100925905(CSGALNACT2)
PCW: 110196399(CSGALNACT1) 110221474(CSGALNACT2)
TVP: 118829092(CSGALNACT2) 118843371(CSGALNACT1)
OAA: 100076249(CSGALNACT2) 100078026(CSGALNACT1)
GGA: 422488(CSGALNACT1) 423632(CSGALNACT2)
PCOC: 116234735(CSGALNACT2) 116238085(CSGALNACT1)
MGP: 100538576(CSGALNACT1) 100550089(CSGALNACT2)
CJO: 107313214(CSGALNACT1) 107315593(CSGALNACT2)
TPAI: 128077919(CSGALNACT2)
LMUT: 125692139(CSGALNACT1) 125693145(CSGALNACT2)
NMEL: 110397662(CSGALNACT1) 110400505(CSGALNACT2)
APLA: 101796158(CSGALNACT2) 101799131(CSGALNACT1)
ACYG: 106032482(CSGALNACT2) 106035122(CSGALNACT1)
CATA: 118243770(CSGALNACT1) 118245852(CSGALNACT2)
AFUL: 116489274(CSGALNACT1) 116491372(CSGALNACT2)
TGU: 100223510(CSGALNACT1) 100231851(CSGALNACT2)
LSR: 110468615(CSGALNACT2) 110471712(CSGALNACT1)
SCAN: 103814021(CSGALNACT2) 103825992(CSGALNACT1)
PMOA: 120502749(CSGALNACT1) 120507270(CSGALNACT2)
OTC: 121336165(CSGALNACT2) 121348464(CSGALNACT1)
PRUF: 121357788(CSGALNACT2) 121360235(CSGALNACT1)
GFR: 102033481(CSGALNACT1) 102043050(CSGALNACT2)
FAB: 101812240(CSGALNACT1) 101820745(CSGALNACT2)
OMA: 130252377(CSGALNACT1) 130254919(CSGALNACT2)
PHI: 102113363(CSGALNACT2) 102113419(CSGALNACT1)
PMAJ: 107203353(CSGALNACT1) 107207041(CSGALNACT2)
CCAE: 111931022(CSGALNACT2) 111944213(CSGALNACT1)
CCW: 104690220(CSGALNACT2) 104697139(CSGALNACT1)
CBRC: 103617339(CSGALNACT1) 103623686(CSGALNACT2)
ETL: 114062182(CSGALNACT1) 114062797(CSGALNACT2)
ZAB: 102062833(CSGALNACT1) 102068072(CSGALNACT2)
ZLE: 135446747(CSGALNACT1) 135449716(CSGALNACT2)
ACHL: 103806738(CSGALNACT2) 103810931(CSGALNACT1)
SVG: 106854214(CSGALNACT2) 106862842(CSGALNACT1)
MMEA: 130573059(CSGALNACT2) 130576244(CSGALNACT1)
HRT: 120753216(CSGALNACT1) 120755937(CSGALNACT2)
FPG: 101910473(CSGALNACT1) 101919107(CSGALNACT2)
FCH: 102049509(CSGALNACT2) 102059429(CSGALNACT1)
CLV: 102088612(CSGALNACT1) 102097544(CSGALNACT2)
EGZ: 104129088(CSGALNACT2) 104135540(CSGALNACT1)
NNI: 104015153(CSGALNACT2) 104021307(CSGALNACT1)
PCRI: 104037366(CSGALNACT1) 104037536(CSGALNACT2)
PLET: 104621121(CSGALNACT2) 104627346
EHS: 104509902(CSGALNACT2) 104516033(CSGALNACT1)
PCAO: 104039874(CSGALNACT2) 104042336(CSGALNACT1)
ACUN: 113479811(CSGALNACT1) 113483540(CSGALNACT2)
TALA: 104358412(CSGALNACT1) 104358481(CSGALNACT2)
PADL: 103924202(CSGALNACT2) 103925418(CSGALNACT1)
AFOR: 103894249(CSGALNACT1) 103898540(CSGALNACT2)
ACHC: 115343740(CSGALNACT1) 115348268(CSGALNACT2)
HALD: 104318545(CSGALNACT2) 104325280(CSGALNACT1)
HLE: 104831928(CSGALNACT2) 104843361(CSGALNACT1)
CCRI: 104165744(CSGALNACT2) 104169286(CSGALNACT1)
CSTI: 104550532(CSGALNACT2) 104557409(CSGALNACT1)
CMAC: 104481247(CSGALNACT1) 104482113
MUI: 104539156(CSGALNACT2) 104540653(CSGALNACT1)
BREG: 104640022(CSGALNACT1) 104643438(CSGALNACT2)
FGA: 104069672(CSGALNACT1) 104080048(CSGALNACT2)
GSTE: 104256129(CSGALNACT1) 104256686
LDI: 104343717(CSGALNACT1) 104348116(CSGALNACT2)
MNB: 103773081(CSGALNACT2) 103782130(CSGALNACT1)
OHA: 104329197(CSGALNACT1) 104333621(CSGALNACT2)
NNT: 104405593(CSGALNACT2) 104410665(CSGALNACT1)
SHAB: 115607826(CSGALNACT2) 115610883(CSGALNACT1)
DPUB: 104298829(CSGALNACT2) 104304155(CSGALNACT1)
PGUU: 104465114(CSGALNACT1) 104470896(CSGALNACT2)
ACAR: 104525152(CSGALNACT2) 104528378(CSGALNACT1)
CPEA: 104389163(CSGALNACT2) 104398865(CSGALNACT1)
AVIT: 104272205(CSGALNACT1) 104278621(CSGALNACT2)
CVF: 104282995(CSGALNACT1) 104286025(CSGALNACT2)
RTD: 128910288(CSGALNACT1) 128911467(CSGALNACT2)
CUCA: 104063040(CSGALNACT2) 104064685(CSGALNACT1)
TEO: 104372571 104384444(CSGALNACT2)
BRHI: 104500084(CSGALNACT1) 104502237(CSGALNACT2)
AAM: 106484360(CSGALNACT1) 106498950(CSGALNACT2)
AROW: 112972176(CSGALNACT1) 112973043(CSGALNACT2)
NPD: 112950503(CSGALNACT2) 112953461(CSGALNACT1)
TGT: 104576501(CSGALNACT2) 104577668(CSGALNACT1)
DNE: 112993256(CSGALNACT1) 112993301(CSGALNACT2)
SCAM: 104152072(CSGALNACT1) 104152623(CSGALNACT2)
ASN: 102388579(CSGALNACT2) 102388616(CSGALNACT1)
AMJ: 102562660(CSGALNACT2) 106736723(CSGALNACT1)
CPOO: 109309424(CSGALNACT1) 109324110(CSGALNACT2)
GGN: 109287343(CSGALNACT2) 109301225(CSGALNACT1)
PSS: 102447091(CSGALNACT1) 102458703(CSGALNACT2)
CMY: 102940405(CSGALNACT2) 102945055(CSGALNACT1)
CCAY: 125635823(CSGALNACT1) 125639371(CSGALNACT2)
DCC: 119855159(CSGALNACT1) 119858726(CSGALNACT2)
CPIC: 101937753(CSGALNACT2) 101950451(CSGALNACT1)
TST: 117877837(CSGALNACT1) 117880325(CSGALNACT2)
CABI: 116828261(CSGALNACT2) 116834478(CSGALNACT1)
MRV: 120369006(CSGALNACT2) 120406834(CSGALNACT1)
ACS: 100558813(csgalnact2) 100560783(csgalnact1)
ASAO: 132771275(CSGALNACT2) 132778436(CSGALNACT1)
PVT: 110083670(CSGALNACT2) 110086324(CSGALNACT1)
SUND: 121927380(CSGALNACT2) 121935771(CSGALNACT1)
PBI: 103048163(CSGALNACT1) 103058428(CSGALNACT2)
PMUR: 107293256(CSGALNACT2) 107302358(CSGALNACT1)
CTIG: 120302657(CSGALNACT1) 120306828(CSGALNACT2)
TSR: 106549275(CSGALNACT1) 106551544(CSGALNACT2)
PGUT: 117664777(CSGALNACT1) 117669198 132708870
APRI: 131196944(CSGALNACT1) 131201265(CSGALNACT2)
PTEX: 113445402(CSGALNACT2) 113447280(CSGALNACT1)
NSS: 113419136(CSGALNACT2) 113420104(CSGALNACT1)
VKO: 123018334(CSGALNACT2) 123031904(CSGALNACT1)
PMUA: 114581524(CSGALNACT1) 114597096(CSGALNACT2)
PRAF: 128400662(CSGALNACT1) 128413776(CSGALNACT2)
ZVI: 118095372(CSGALNACT1) 118096363(CSGALNACT2)
HCG: 128329111(CSGALNACT1) 128351196(CSGALNACT2)
GJA: 107107034(CSGALNACT1) 107115005(CSGALNACT2)
STOW: 125438154(CSGALNACT2) 125440721(CSGALNACT1)
EMC: 129331859(CSGALNACT2) 129337427(CSGALNACT1)
XLA: 108696289(csgalnact2.L) 108706822(csgalnact1.S) 108712229(csgalnact1.L)
XTR: 100124741(csgalnact2) 100497098(csgalnact1)
NPR: 108786604(CSGALNACT2) 108804915(CSGALNACT1)
RTEM: 120909056(CSGALNACT2) 120914590(CSGALNACT1)
BBUF: 120989661(CSGALNACT1) 121004015(CSGALNACT2)
BGAR: 122940592(CSGALNACT2) 122945826(CSGALNACT1)
MUO: 115463756(CSGALNACT1) 115470248(CSGALNACT2)
GSH: 117346041(CSGALNACT1) 117359422(CSGALNACT2)
DRE: 101886904(csgalnact1b) 560826(csgalnact2) 793671(csgalnact1a)
SRX: 107712620 107713273 107726950(csgalnact2) 107743585 107744099(csgalnact1)
PTET: 122350650(csgalnact1b) 122352957(csgalnact1a) 122356644(csgalnact2)
LROH: 127169277(csgalnact1b) 127172460(csgalnact1a) 127175495(csgalnact2)
OMC: 131545306(csgalnact1b) 131547765(csgalnact1a) 131552362(csgalnact2)
PPRM: 120473219(csgalnact2) 120481690(csgalnact1a)
RKG: 130087132(csgalnact1a) 130089633(csgalnact2)
MAMB: 125257210(csgalnact1a) 125276927(csgalnact2) 125280316(csgalnact1b)
TROS: 130546355(csgalnact1a) 130559354(csgalnact2) 130567628(csgalnact1b)
TDW: 130412032(csgalnact1a) 130431144(csgalnact2) 130440390(csgalnact1b)
MANU: 129413835(csgalnact1b) 129416317(csgalnact2) 129447248(csgalnact1a)
IPU: 108263569 108265223(csgalnact1b) 108277248(csgalnact1a)
IFU: 128605779(csgalnact2) 128607246(csgalnact1b) 128619999(csgalnact1a)
PHYP: 113533267 113541925(csgalnact2) 113543992
SMEO: 124393878(csgalnact1a) 124399478(csgalnact1b) 124400886(csgalnact2)
TFD: 113636285(csgalnact2) 113656118(csgalnact1b) 113661309(csgalnact1a)
TVC: 132847391(csgalnact2) 132853743(csgalnact1b) 132863288(csgalnact1a)
TRN: 134314231(csgalnact2) 134317553 134332616(csgalnact1a)
AMEX: 103021869(csgalnact1b) 103029300(csgalnact2) 103045746(csgalnact1a)
CMAO: 118810506(csgalnact2) 118814064 118824873(csgalnact1a)
EEE: 113585223(csgalnact2) 113590383
CHAR: 105889462(csgalnact1b) 105909075 122130312(csgalnact2)
TRU: 101071007 101079052(csgalnact2) 101079135
TFS: 130517592(csgalnact1a) 130526558 130533911(csgalnact2)
LCO: 104920113(csgalnact1) 104920841 104921883(csgalnact2)
NCC: 104951713 104952731(csgalnact2)
TBEN: 117473022 117478886 117499606(csgalnact2)
CGOB: 115013493 115017153 115019876(csgalnact2)
PGEO: 117452984 117459531(csgalnact2)
GACU: 117552366(csgalnact2) 117558653
EMAC: 134859187(csgalnact2) 134867971(csgalnact1a) 134873084
ELY: 117248332(csgalnact2) 117251871 117269179 117269204(csgalnact1a)
EFO: 125878626(csgalnact1a) 125890991 125903769(csgalnact2)
PLEP: 121944169 121954782(csgalnact2) 121959976(csgalnact1a)
SLUC: 116039395(csgalnact2) 116054357 116062907(csgalnact1a)
ECRA: 117945314 117959414(csgalnact1a) 117960648(csgalnact2)
ESP: 116683580(csgalnact2) 116690123 116704793(csgalnact1)
PFLV: 114556240 114571591(csgalnact1) 114572117(csgalnact2)
GAT: 120820244(csgalnact2) 120830859 120831634(csgalnact1a)
PPUG: 119214041(csgalnact2) 119224975 119226953(csgalnact1a)
AFB: 129091929(csgalnact2) 129101019 129102122(csgalnact1a)
CLUM: 117736502 117740319(csgalnact1a) 117743677(csgalnact2)
PSWI: 130196915 130205367(csgalnact1a) 130206838(csgalnact2)
MSAM: 119892062 119914529(csgalnact1a) 119917420(csgalnact2)
SCHU: 122865562(csgalnact1a) 122876915 122884861(csgalnact2)
CUD: 121510272 121511297(csgalnact2) 121525580(csgalnact1a)
ALAT: 119019894 119030081(csgalnact1a) 119033026(csgalnact2)
MZE: 101469922(csgalnact1) 101474654 101476345(csgalnact2)
ONL: 100702075(csgalnact2) 100706120 100708917
OAU: 116310492(csgalnact1b) 116318798(csgalnact2) 116331736(csgalnact1a)
OLA: 101155793(csgalnact2) 101159591 101162617(csgalnact1)
OML: 112140415 112148788 112161592(csgalnact2) 112163495(csgalnact1a)
CSAI: 133450626 133454935(csgalnact1a) 133464032(csgalnact2)
XMA: 102221723(csgalnact1) 102233977 102237743(csgalnact2)
XCO: 114137572(csgalnact2) 114149526(csgalnact1) 114154568
XHE: 116713231 116724307(csgalnact1) 116729792
PRET: 103470100 103473476(csgalnact1) 103477114(csgalnact2)
PFOR: 103141822 103142702 103148243(csgalnact2)
PLAI: 106941788 106944945 106951788(csgalnact2)
PMEI: 106912280 106920942(csgalnact2) 106924707
GAF: 122827458 122842267(csgalnact2) 122846841(csgalnact1a)
PPRL: 129352642(csgalnact2) 129365738 129374229(csgalnact1a)
CVG: 107086272 107088483(csgalnact2) 107088980
CTUL: 119776575(csgalnact1a) 119782922(csgalnact2) 119798533
GMU: 124859018(csgalnact2) 124872656(csgalnact1a) 124877422
NFU: 107373900(csgalnact1) 107375371(csgalnact2) 107394138
KMR: 108231091(csgalnact1a) 108233606 108240679(csgalnact2)
NWH: 119413037 119417530(csgalnact2) 119424842(csgalnact1a)
AOCE: 111564714 111564820(csgalnact1) 111573086(csgalnact2)
CSEM: 103387459(csgalnact2) 103390413(csgalnact1) 103397716
POV: 109626572 109632851(csgalnact2) 109637154
SSEN: 122758252(csgalnact1a) 122769482 122781771(csgalnact2)
HHIP: 117768538 117772080(csgalnact1a) 117775771(csgalnact2)
HSP: 118115258 118118841(csgalnact2) 118125681(csgalnact1a)
PPLT: 128425036(csgalnact1a) 128438277 128453263(csgalnact2)
SMAU: 118283944(csgalnact2) 118285191(csgalnact1a) 118314573
SDU: 111220601(csgalnact2) 111230915 111239886(csgalnact1)
SLAL: 111645131 111656793(csgalnact1) 111669464
XGL: 120796223(csgalnact2) 120805287 120806778(csgalnact1a)
HCQ: 109523133(csgalnact2) 109525674 109527907
SBIA: 133490665(csgalnact1a) 133509821(csgalnact2)
PEE: 133400580 133409549(csgalnact2) 133413602(csgalnact1a)
PTAO: 133465272(csgalnact1a) 133475208 133486221(csgalnact2)
BPEC: 110157439 110162232(csgalnact2) 110167048
MALB: 109956612 109960538(csgalnact2) 109972367
BSPL: 114842204(csgalnact2) 114862672 114866488(csgalnact1a)
SJO: 128364903 128372604(csgalnact2) 128380363(csgalnact1a)
ELS: 105014092 105026679(csgalnact1) 105028646(csgalnact2)
SFM: 108924956(csgalnact1) 108932703(csgalnact2)
PKI: 111849050(csgalnact2) 111849915(csgalnact1)
AANG: 118206747(csgalnact1b) 118212966(csgalnact1a) 118218071(csgalnact2)
LOC: 102686672(csgalnact2) 102694271(csgalnact1)
PSPA: 121304057(csgalnact1a) 121314225 121325711(csgalnact2)
ARUT: 117408808 117418452(csgalnact2) 117420659(csgalnact1a)
PSEX: 120527199(csgalnact1a) 120529200(csgalnact2)
LCM: 102358556(CSGALNACT2) 102366614(CSGALNACT1)
CMK: 103181211(csgalnact2) 103186731
RTP: 109912510(csgalnact2)
CPLA: 122539454 122541904(csgalnact2)
HOC: 132833350 132834922(csgalnact2)
LERI: 129701196 129712933(csgalnact2)
PMRN: 116956930
LRJ: 133359474
BFO: 118410920
BBEL: 109485484
CIN: 100177589
SPU: 579124
LPIC: 129281811
APLC: 110991016
AJC: 117123315
SKO: 100368195
DME: Dmel_CG12913(Csgalnact)
DER: 6543177
DSE: 6608480
DSI: Dsimw501_GD10724(Dsim_GD10724)
DAN: 6495632
DSR: 110178256
DPO: 4804207
DPE: 6590525
DMN: 108159923
DWI: 6646033
DGR: 6560215
DAZ: 108615801
DNV: 108653728
DVI: 6625749
TDA: 119679725
ECOE: 129948994
CLON: 129611172
HIS: 119646653
AGA: 1269523
ACOZ: 120953354
AARA: 120893196
AMER: 121594790
AFUN: 125767271
AMOU: 128302003
AALI: 118465303
AAG: 5578232
ASUA: 134208734
CPII: 120425696
CNS: 116345176
BCOO: 119083657
NVI: 100121958
CSOL: 105364133
TPRE: 106650500
LHT: 122498055
LBD: 127287746
MDL: 103578840
CGLO: 123262930
FAS: 105268100
DAM: 107041616
AGIF: 122854813
CINS: 118064942
VCAN: 122409117
CCIN: 107270238
DSM: 124404876
NPT: 124215875
NFB: 124178283
NLO: 107225156
NVG: 124299932
AROA: 105690400
TCA: 659298
DPA: 109542837
SOY: 115886992
AGRG: 126733928
ATD: 109600607
CSET: 123314829
AGB: 108911720
LDC: 111503128
DVV: 126887302
NVL: 108559669
PPYR: 116163942
OTU: 111420233
CFEL: 113384842
CCRN: 123299712
BTAB: 109034694
CLEC: 112126951
HHAL: 106691779
NLU: 111056642
HVI: 124358995
MQU: 128988075
ZNE: 110838755
BROR: 134535534
DMK: 116932720
DPZ: 124350587
LPOL: 106457953
PVUL: 126810810
PCAN: 112575074
BGT: 106055870
GAE: 121380061
HRF: 124142722
HRJ: 124275673
CRG: 105325571
CANU: 128166277
CVN: 111121591
OED: 125672055
MYI: 110456749
PMAX: 117330640
MCAF: 127707614
MMER: 123563253
RPHI: 132719622
MAEA: 128225193
OBI: 106881725
OSN: 115225312
LJP: 135469135
LAK: 106167613
LLON: 135483244
DGT: 114517412
AQU: 105313529
 » show all
Reference
  Authors
Uyama T, Kitagawa H, Tamura Ji J, Sugahara K
  Title
Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
  Journal
J Biol Chem 277:8841-6 (2002)
DOI:10.1074/jbc.M111434200
  Sequence
[hsa:55790]
LinkDB

KEGG   ENZYME: 2.4.1.174
Entry
EC 2.4.1.174                Enzyme                                 
Name
glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase;
N-acetylgalactosaminyltransferase I;
glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase;
uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I;
UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase;
UDP-N-acetyl-D-galactosamine:D-glucuronyl-(1->3)-beta-D-galactosyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-D-galactosamine:[protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine 4-beta-N-acetylgalactosaminyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-galactosamine + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine = UDP + [protein]-3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine [RN:R05929]
Reaction(KEGG)
R05929(G)
Substrate
UDP-N-acetyl-alpha-D-galactosamine [CPD:C00203];
[protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine [CPD:C04903]
Product
UDP [CPD:C00015];
[protein]-3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine
Comment
Requires Mn2+. Involved in the biosynthesis of chondroitin sulfate. Key enzyme activity for the initiation of chondroitin and dermatan sulfates, transferring GalNAc to the GlcA-Gal-Gal-Xyl-Ser core.
History
EC 2.4.1.174 created 1989, modified 2002
Pathway
ec00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
ec01100  Metabolic pathways
Orthology
K00746  chondroitin sulfate N-acetylgalactosaminyltransferase 1/2
Genes
HSA55454(CSGALNACT2) 55790(CSGALNACT1)
PTR450416 464030
PPS100987599(CSGALNACT1) 100994377(CSGALNACT2)
GGO101151962 101154228
PON100172853(CSGALNACT2) 100442293(CSGALNACT1)
PPYG129042717 129045307
NLE100583001(CSGALNACT1) 100602432(CSGALNACT2)
HMH116461304(CSGALNACT2) 116473758(CSGALNACT1)
SSYN129480840 129486436
MCC703703(CSGALNACT2) 704901(CSGALNACT1)
MCF102136560
MTHB126961445 126962794
MNI105482127(CSGALNACT1) 105486613(CSGALNACT2)
CSAB103215414(CSGALNACT1) 103215756(CSGALNACT2)
CATY105571571(CSGALNACT2) 105579259(CSGALNACT1)
PANU101012979(CSGALNACT1) 101019767(CSGALNACT2)
TGE112630090(CSGALNACT1) 112632117(CSGALNACT2)
MLEU105534463(CSGALNACT2) 105539379(CSGALNACT1)
RRO104653929(CSGALNACT2) 104662459(CSGALNACT1)
RBB108513317(CSGALNACT2) 108526479(CSGALNACT1)
TFN117082810(CSGALNACT2) 117092780(CSGALNACT1)
PTEH111531316(CSGALNACT2) 111545662(CSGALNACT1)
CANG105510156(CSGALNACT1) 105520188(CSGALNACT2)
CJC100399122(CSGALNACT2) 100407007(CSGALNACT1)
SBQ101027448(CSGALNACT2) 101048885(CSGALNACT1)
CIMI108296689(CSGALNACT2) 108312008(CSGALNACT1)
ANAN105705382(CSGALNACT1) 105734323(CSGALNACT2)
CSYR103268660(CSGALNACT2) 103276583(CSGALNACT1)
MMUR105879006(CSGALNACT2) 105882547(CSGALNACT1)
LCAT123626380(CSGALNACT1) 123649892(CSGALNACT2)
PCOQ105818036 105825209(CSGALNACT1)
OGA100942846(CSGALNACT2) 100948840(CSGALNACT1)
MMU234356(Csgalnact1) 78752(Csgalnact2)
MCAL110295750(Csgalnact2) 110300279(Csgalnact1)
MPAH110315909(Csgalnact2) 110336490(Csgalnact1)
RNO297554(Csgalnact2) 306375(Csgalnact1)
MCOC116069408(Csgalnact1) 116099473(Csgalnact2)
ANU117715225(Csgalnact2) 117722009(Csgalnact1)
MUN110549131(Csgalnact1) 110558018(Csgalnact2)
CGE100754969(Csgalnact1) 100770830(Csgalnact2)
MAUA101825715(Csgalnact2) 101840817(Csgalnact1)
PROB127216397 127220204(Csgalnact1) 127236114(Csgalnact2)
PLEU114689661(Csgalnact2) 114703120(Csgalnact1)
MORG121439905(Csgalnact2) 121462726(Csgalnact1)
MFOT126491344 126505489
AAMP119807926(Csgalnact2) 119812027(Csgalnact1)
NGI103733802(Csgalnact2) 103747604(Csgalnact1)
HGL101700905(Csgalnact1) 101719048(Csgalnact2)
CPOC100725703(Csgalnact1) 100735627(Csgalnact2)
CCAN109688882(Csgalnact1) 109698852(Csgalnact2)
DORD105992963(Csgalnact1) 105998871(Csgalnact2)
DSP122122368(Csgalnact2) 122125664(Csgalnact1)
PLOP125339260(Csgalnact1) 125346567(Csgalnact2)
NCAR124983508 124985353
MMMA107153395(Csgalnact2) 107153954(Csgalnact1)
OCU100339411 100339435
OPI101526745(CSGALNACT1) 101533692(CSGALNACT2)
TUP102468989(CSGALNACT2) 102490797(CSGALNACT1)
GVR103603622(CSGALNACT1) 103605928(CSGALNACT2) 103607542
CFA482831(CSGALNACT1) 486786(CSGALNACT2)
CLUD112659138(CSGALNACT1) 112672018(CSGALNACT2)
VVP112913575(CSGALNACT2) 112916171(CSGALNACT1)
VLG121484927(CSGALNACT2) 121489366(CSGALNACT1)
NPO129515892(CSGALNACT1) 129520737 129522808(CSGALNACT2)
AML100468746(CSGALNACT1) 100484755(CSGALNACT2)
UMR103667936(CSGALNACT2) 103677036(CSGALNACT1)
UAH113243134(CSGALNACT2) 113245577(CSGALNACT1)
UAR123780323(CSGALNACT1) 123800371(CSGALNACT2)
ELK111144616 111144844
LLV125084558 125092818
MPUF101683049(CSGALNACT2) 101693101(CSGALNACT1)
MNP132006455(CSGALNACT1) 132016599(CSGALNACT2)
MLK131820662(CSGALNACT1) 131828681(CSGALNACT2)
NVS122889841(CSGALNACT1) 122900897(CSGALNACT2)
ORO101369554(CSGALNACT2) 101377082(CSGALNACT1)
EJU114205257(CSGALNACT2) 114224798(CSGALNACT1)
ZCA113919765(CSGALNACT2) 113924441(CSGALNACT1)
MLX118009903(CSGALNACT1) 118023420(CSGALNACT2)
NSU110573168(CSGALNACT1) 110589538(CSGALNACT2)
LWW102726550(CSGALNACT2) 102735074(CSGALNACT1)
FCA101096311(CSGALNACT1) 101100841(CSGALNACT2)
PYU121036967(CSGALNACT2) 121045298(CSGALNACT1)
PCOO112854603(CSGALNACT2) 112858443(CSGALNACT1)
PBG122472766(CSGALNACT1) 122493001(CSGALNACT2)
PVIV125147674(CSGALNACT2) 125164151(CSGALNACT1)
LRUF124506976 124520867
PTG102956824(CSGALNACT1) 102966347(CSGALNACT2)
PPAD109262244(CSGALNACT1) 109264614(CSGALNACT2)
PUC125923842 125933343
AJU106972130 106978257
HHV120234018(CSGALNACT1) 120249250(CSGALNACT2)
BTA509328(CSGALNACT2) 528057(CSGALNACT1)
BOM102266543(CSGALNACT1) 102285203(CSGALNACT2)
BIU109553356(CSGALNACT1) 109553754(CSGALNACT2)
BBUB102402654 102406891
BBIS104993236(CSGALNACT1) 104997317(CSGALNACT2)
CHX102179349(CSGALNACT1) 102185714(CSGALNACT2)
OAS101118243(CSGALNACT2) 101120469(CSGALNACT1)
BTAX128048892(CSGALNACT2) 128068254(CSGALNACT1)
ODA120852941 120860459 120865386 120865866(CSGALNACT1)
CCAD122432632 122446561
MBEZ129549446(CSGALNACT1) 129555825(CSGALNACT2)
SSC100157878(CSGALNACT2) 100517735 102166124(CSGALNACT1)
CFR102513810(CSGALNACT1) 102514190(CSGALNACT2)
CBAI105071120(CSGALNACT1) 105072700(CSGALNACT2)
CDK105086444(CSGALNACT1) 105092509(CSGALNACT2)
VPC102525594(CSGALNACT1) 102542681(CSGALNACT2)
BACU103007226(CSGALNACT2) 103010484(CSGALNACT1)
BMUS118882632(CSGALNACT2) 118887822(CSGALNACT1)
LVE103069443(CSGALNACT2) 103084873(CSGALNACT1)
OOR101288535(CSGALNACT2) 101289782(CSGALNACT1)
DLE111163996(CSGALNACT2) 111173568(CSGALNACT1)
PCAD102982515(CSGALNACT1) 102984892(CSGALNACT2)
PSIU116741260(CSGALNACT2) 116746869(CSGALNACT1)
NASI112403826(CSGALNACT2) 112413251(CSGALNACT1)
ECB100050200(CSGALNACT2) 100052192(CSGALNACT1)
EPZ103550620(CSGALNACT2)
EAI106824857(CSGALNACT1) 106831340(CSGALNACT2)
MYB102244364(CSGALNACT1) 102262652(CSGALNACT2)
MYD102764495(CSGALNACT2) 102768920(CSGALNACT1)
MMYO118651294(CSGALNACT1) 118670214(CSGALNACT2)
MLF102435977(CSGALNACT1) 102443242(CSGALNACT2)
PKL118719057(CSGALNACT2) 118730871(CSGALNACT1)
EFUS103288197(CSGALNACT1) 103292851(CSGALNACT2)
MNA107523899(CSGALNACT1) 107532565(CSGALNACT2)
DRO112305453(CSGALNACT2) 112321495(CSGALNACT1)
SHON118981053(CSGALNACT2) 118984282(CSGALNACT1)
AJM119035897(CSGALNACT2) 119060903(CSGALNACT1)
PDIC114497160(CSGALNACT2) 114508884(CSGALNACT1)
PHAS123807620(CSGALNACT1) 123820932(CSGALNACT2)
MMF118622397 118622545 118632143(CSGALNACT2)
PPAM129064775(CSGALNACT1) 129073177(CSGALNACT2)
HAI109386291(CSGALNACT1) 109395550(CSGALNACT2)
RFQ117021457(CSGALNACT1) 117036051(CSGALNACT2)
PALE102878385(CSGALNACT2) 102889741(CSGALNACT1)
PGIG120594629(CSGALNACT2) 120613141(CSGALNACT1)
PVP105300712(CSGALNACT1) 105309192(CSGALNACT2)
RAY107501339(CSGALNACT1) 107517640(CSGALNACT2)
MJV108403396(CSGALNACT1) 108408000(CSGALNACT2)
TOD119233514(CSGALNACT2) 119257867(CSGALNACT1)
SARA101539058 101551713(CSGALNACT1) 101556437(CSGALNACT2)
SETR125995073(CSGALNACT2) 126006427(CSGALNACT1)
LAV100654033(CSGALNACT1) 100661660(CSGALNACT2)
TMU101345134 101352592
ETF101651335(CSGALNACT2) 101660160(CSGALNACT1)
DNM101413578(CSGALNACT2) 101443515(CSGALNACT1)
MDO100012272(CSGALNACT2) 100030310(CSGALNACT1)
GAS123234841(CSGALNACT1) 123236401(CSGALNACT2)
SHR100925396(CSGALNACT1) 100925905(CSGALNACT2)
AFZ127548291 127551862
PCW110196399(CSGALNACT1) 110221474(CSGALNACT2)
TVP118829092(CSGALNACT2) 118843371(CSGALNACT1)
OAA100076249(CSGALNACT2) 100078026(CSGALNACT1)
GGA422488(CSGALNACT1) 423632(CSGALNACT2)
PCOC116234735(CSGALNACT2) 116238085(CSGALNACT1)
MGP100538576(CSGALNACT1) 100550089(CSGALNACT2)
CJO107313214(CSGALNACT1) 107315593(CSGALNACT2)
TPAI128077919(CSGALNACT2)
LMUT125692139(CSGALNACT1) 125693145(CSGALNACT2)
NMEL110397662(CSGALNACT1) 110400505(CSGALNACT2)
APLA101796158(CSGALNACT2) 101799131(CSGALNACT1)
ACYG106032482(CSGALNACT2) 106035122(CSGALNACT1)
CATA118243770(CSGALNACT1) 118245852(CSGALNACT2)
AFUL116489274(CSGALNACT1) 116491372(CSGALNACT2)
TGU100223510(CSGALNACT1) 100231851(CSGALNACT2)
LSR110468615(CSGALNACT2) 110471712(CSGALNACT1)
SCAN103814021(CSGALNACT2) 103825992(CSGALNACT1)
PMOA120502749(CSGALNACT1) 120507270(CSGALNACT2)
OTC121336165(CSGALNACT2) 121348464(CSGALNACT1)
PRUF121357788(CSGALNACT2) 121360235(CSGALNACT1)
GFR102033481(CSGALNACT1) 102043050(CSGALNACT2)
FAB101812240(CSGALNACT1) 101820745(CSGALNACT2)
OMA130252377(CSGALNACT1) 130254919(CSGALNACT2)
PHI102113363(CSGALNACT2) 102113419(CSGALNACT1)
PMAJ107203353(CSGALNACT1) 107207041(CSGALNACT2)
CCAE111931022(CSGALNACT2) 111944213(CSGALNACT1)
CCW104690220(CSGALNACT2) 104697139(CSGALNACT1)
CBRC103617339(CSGALNACT1) 103623686(CSGALNACT2)
ETL114062182(CSGALNACT1) 114062797(CSGALNACT2)
ZAB102062833(CSGALNACT1) 102068072(CSGALNACT2)
ZLE135446747(CSGALNACT1) 135449716(CSGALNACT2)
ACHL103806738(CSGALNACT2) 103810931(CSGALNACT1)
SVG106854214(CSGALNACT2) 106862842(CSGALNACT1)
MMEA130573059(CSGALNACT2) 130576244(CSGALNACT1)
HRT120753216(CSGALNACT1) 120755937(CSGALNACT2)
FPG101910473(CSGALNACT1) 101919107(CSGALNACT2)
FCH102049509(CSGALNACT2) 102059429(CSGALNACT1)
CLV102088612(CSGALNACT1) 102097544(CSGALNACT2)
EGZ104129088(CSGALNACT2) 104135540(CSGALNACT1)
NNI104015153(CSGALNACT2) 104021307(CSGALNACT1)
PCRI104037366(CSGALNACT1) 104037536(CSGALNACT2)
PLET104621121(CSGALNACT2) 104627346
EHS104509902(CSGALNACT2) 104516033(CSGALNACT1)
PCAO104039874(CSGALNACT2) 104042336(CSGALNACT1)
ACUN113479811(CSGALNACT1) 113483540(CSGALNACT2)
TALA104358412(CSGALNACT1) 104358481(CSGALNACT2)
PADL103924202(CSGALNACT2) 103925418(CSGALNACT1)
AFOR103894249(CSGALNACT1) 103898540(CSGALNACT2)
ACHC115343740(CSGALNACT1) 115348268(CSGALNACT2)
HALD104318545(CSGALNACT2) 104325280(CSGALNACT1)
HLE104831928(CSGALNACT2) 104843361(CSGALNACT1)
AGEN126042567 126044867
GCL127015743 127017788
CCRI104165744(CSGALNACT2) 104169286(CSGALNACT1)
CSTI104550532(CSGALNACT2) 104557409(CSGALNACT1)
CMAC104481247(CSGALNACT1) 104482113
MUI104539156(CSGALNACT2) 104540653(CSGALNACT1)
BREG104640022(CSGALNACT1) 104643438(CSGALNACT2)
FGA104069672(CSGALNACT1) 104080048(CSGALNACT2)
GSTE104256129(CSGALNACT1) 104256686
LDI104343717(CSGALNACT1) 104348116(CSGALNACT2)
MNB103773081(CSGALNACT2) 103782130(CSGALNACT1)
OHA104329197(CSGALNACT1) 104333621(CSGALNACT2)
NNT104405593(CSGALNACT2) 104410665(CSGALNACT1)
SHAB115607826(CSGALNACT2) 115610883(CSGALNACT1)
DPUB104298829(CSGALNACT2) 104304155(CSGALNACT1)
PGUU104465114(CSGALNACT1) 104470896(CSGALNACT2)
ACAR104525152(CSGALNACT2) 104528378(CSGALNACT1)
CPEA104389163(CSGALNACT2) 104398865(CSGALNACT1)
AVIT104272205(CSGALNACT1) 104278621(CSGALNACT2)
CVF104282995(CSGALNACT1) 104286025(CSGALNACT2)
RTD128910288(CSGALNACT1) 128911467(CSGALNACT2)
CUCA104063040(CSGALNACT2) 104064685(CSGALNACT1)
TEO104372571 104384444(CSGALNACT2)
BRHI104500084(CSGALNACT1) 104502237(CSGALNACT2)
AAM106484360(CSGALNACT1) 106498950(CSGALNACT2)
AROW112972176(CSGALNACT1) 112973043(CSGALNACT2)
NPD112950503(CSGALNACT2) 112953461(CSGALNACT1)
TGT104576501(CSGALNACT2) 104577668(CSGALNACT1)
DNE112993256(CSGALNACT1) 112993301(CSGALNACT2)
SCAM104152072(CSGALNACT1) 104152623(CSGALNACT2)
ASN102388579(CSGALNACT2) 102388616(CSGALNACT1)
AMJ102562660(CSGALNACT2) 106736723(CSGALNACT1)
CPOO109309424(CSGALNACT1) 109324110(CSGALNACT2)
GGN109287343(CSGALNACT2) 109301225(CSGALNACT1)
PSS102447091(CSGALNACT1) 102458703(CSGALNACT2)
CMY102940405(CSGALNACT2) 102945055(CSGALNACT1)
CCAY125635823(CSGALNACT1) 125639371(CSGALNACT2)
DCC119855159(CSGALNACT1) 119858726(CSGALNACT2)
CPIC101937753(CSGALNACT2) 101950451(CSGALNACT1)
TST117877837(CSGALNACT1) 117880325(CSGALNACT2)
CABI116828261(CSGALNACT2) 116834478(CSGALNACT1)
MRV120369006(CSGALNACT2) 120406834(CSGALNACT1)
ACS100558813(csgalnact2) 100560783(csgalnact1)
ASAO132771275(CSGALNACT2) 132778436(CSGALNACT1)
PVT110083670(CSGALNACT2) 110086324(CSGALNACT1)
SUND121927380(CSGALNACT2) 121935771(CSGALNACT1)
PBI103048163(CSGALNACT1) 103058428(CSGALNACT2)
PMUR107293256(CSGALNACT2) 107302358(CSGALNACT1)
CTIG120302657(CSGALNACT1) 120306828(CSGALNACT2)
TSR106549275(CSGALNACT1) 106551544(CSGALNACT2)
PGUT117664777(CSGALNACT1) 117669198 132708870
APRI131196944(CSGALNACT1) 131201265(CSGALNACT2)
PTEX113445402(CSGALNACT2) 113447280(CSGALNACT1)
NSS113419136(CSGALNACT2) 113420104(CSGALNACT1)
VKO123018334(CSGALNACT2) 123031904(CSGALNACT1)
PMUA114581524(CSGALNACT1) 114597096(CSGALNACT2)
PRAF128400662(CSGALNACT1) 128413776(CSGALNACT2)
ZVI118095372(CSGALNACT1) 118096363(CSGALNACT2)
HCG128329111(CSGALNACT1) 128351196(CSGALNACT2)
GJA107107034(CSGALNACT1) 107115005(CSGALNACT2)
STOW125438154(CSGALNACT2) 125440721(CSGALNACT1)
EMC129331859(CSGALNACT2) 129337427(CSGALNACT1)
XLA108696289(csgalnact2.L) 108706822(csgalnact1.S) 108712229(csgalnact1.L)
XTR100124741(csgalnact2) 100497098(csgalnact1)
NPR108786604(CSGALNACT2) 108804915(CSGALNACT1)
RTEM120909056(CSGALNACT2) 120914590(CSGALNACT1)
BBUF120989661(CSGALNACT1) 121004015(CSGALNACT2)
BGAR122940592(CSGALNACT2) 122945826(CSGALNACT1)
MUO115463756(CSGALNACT1) 115470248(CSGALNACT2)
GSH117346041(CSGALNACT1) 117359422(CSGALNACT2)
DRE101886904(csgalnact1b) 560826(csgalnact2) 793671(csgalnact1a)
SRX107712620 107713273 107726950(csgalnact2) 107743585 107744099(csgalnact1)
SANH107655442 107661530 107666416 107685172 107686490
SGH107559332 107562546 107569665 107571111(csgalnact1) 107601885
CCAR109078348 109078956 109092168 109094999 109097796(csgalnact1)
CAUA113054105 113056961 113106708 113106887 113110394 113112664
CGIB127964111 127966665 127970163 128021389 128026198
PTET122350650(csgalnact1b) 122352957(csgalnact1a) 122356644(csgalnact2)
LROH127169277(csgalnact1b) 127172460(csgalnact1a) 127175495(csgalnact2)
OMC131545306(csgalnact1b) 131547765(csgalnact1a) 131552362(csgalnact2)
PPRM120473219(csgalnact2) 120481690(csgalnact1a)
RKG130087132(csgalnact1a) 130089633(csgalnact2)
MAMB125257210(csgalnact1a) 125276927(csgalnact2) 125280316(csgalnact1b)
CIDE127517379 127521295 127524443
MASI127412054 127414249 127423860 127432748 127433461
TROS130546355(csgalnact1a) 130559354(csgalnact2) 130567628(csgalnact1b)
TDW130412032(csgalnact1a) 130431144(csgalnact2) 130440390(csgalnact1b)
MANU129413835(csgalnact1b) 129416317(csgalnact2) 129447248(csgalnact1a)
IPU108263569 108265223(csgalnact1b) 108277248(csgalnact1a)
IFU128605779(csgalnact2) 128607246(csgalnact1b) 128619999(csgalnact1a)
PHYP113533267 113541925(csgalnact2) 113543992
SMEO124393878(csgalnact1a) 124399478(csgalnact1b) 124400886(csgalnact2)
TFD113636285(csgalnact2) 113656118(csgalnact1b) 113661309(csgalnact1a)
TVC132847391(csgalnact2) 132853743(csgalnact1b) 132863288(csgalnact1a)
TRN134314231(csgalnact2) 134317553 134332616(csgalnact1a)
AMEX103021869(csgalnact1b) 103029300(csgalnact2) 103045746(csgalnact1a)
CMAO118810506(csgalnact2) 118814064 118824873(csgalnact1a)
EEE113585223(csgalnact2) 113590383
CHAR105889462(csgalnact1b) 105909075 122130312(csgalnact2)
TRU101071007 101079052(csgalnact2) 101079135
TFS130517592(csgalnact1a) 130526558 130533911(csgalnact2)
TNGGSTEN00014453G001 GSTEN00024539G001 GSTEN00030936G001
LCO104920113(csgalnact1) 104920841 104921883(csgalnact2)
NCC104951713 104952731(csgalnact2)
TBEN117473022 117478886 117499606(csgalnact2)
CGOB115013493 115017153 115019876(csgalnact2)
PGEO117452984 117459531(csgalnact2)
GACU117552366(csgalnact2) 117558653
EMAC134859187(csgalnact2) 134867971(csgalnact1a) 134873084
ELY117248332(csgalnact2) 117251871 117269179 117269204(csgalnact1a)
EFO125878626(csgalnact1a) 125890991 125903769(csgalnact2)
PLEP121944169 121954782(csgalnact2) 121959976(csgalnact1a)
SLUC116039395(csgalnact2) 116054357 116062907(csgalnact1a)
ECRA117945314 117959414(csgalnact1a) 117960648(csgalnact2)
ESP116683580(csgalnact2) 116690123 116704793(csgalnact1)
PFLV114556240 114571591(csgalnact1) 114572117(csgalnact2)
GAT120820244(csgalnact2) 120830859 120831634(csgalnact1a)
PPUG119214041(csgalnact2) 119224975 119226953(csgalnact1a)
AFB129091929(csgalnact2) 129101019 129102122(csgalnact1a)
CLUM117736502 117740319(csgalnact1a) 117743677(csgalnact2)
PSWI130196915 130205367(csgalnact1a) 130206838(csgalnact2)
MSAM119892062 119914529(csgalnact1a) 119917420(csgalnact2)
SCHU122865562(csgalnact1a) 122876915 122884861(csgalnact2)
CUD121510272 121511297(csgalnact2) 121525580(csgalnact1a)
ALAT119019894 119030081(csgalnact1a) 119033026(csgalnact2)
MZE101469922(csgalnact1) 101474654 101476345(csgalnact2)
ONL100702075(csgalnact2) 100706120 100708917
OAU116310492(csgalnact1b) 116318798(csgalnact2) 116331736(csgalnact1a)
OLA101155793(csgalnact2) 101159591 101162617(csgalnact1)
OML112140415 112148788 112161592(csgalnact2) 112163495(csgalnact1a)
CSAI133450626 133454935(csgalnact1a) 133464032(csgalnact2)
XMA102221723(csgalnact1) 102233977 102237743(csgalnact2)
XCO114137572(csgalnact2) 114149526(csgalnact1) 114154568
XHE116713231 116724307(csgalnact1) 116729792
PRET103470100 103473476(csgalnact1) 103477114(csgalnact2)
PFOR103141822 103142702 103148243(csgalnact2)
PLAI106941788 106944945 106951788(csgalnact2)
PMEI106912280 106920942(csgalnact2) 106924707
GAF122827458 122842267(csgalnact2) 122846841(csgalnact1a)
PPRL129352642(csgalnact2) 129365738 129374229(csgalnact1a)
CVG107086272 107088483(csgalnact2) 107088980
CTUL119776575(csgalnact1a) 119782922(csgalnact2) 119798533
GMU124859018(csgalnact2) 124872656(csgalnact1a) 124877422
NFU107373900(csgalnact1) 107375371(csgalnact2) 107394138
KMR108231091(csgalnact1a) 108233606 108240679(csgalnact2)
ALIM106513683 106525614 106533027 106535117
NWH119413037 119417530(csgalnact2) 119424842(csgalnact1a)
AOCE111564714 111564820(csgalnact1) 111573086(csgalnact2)
MCEP124996852 125011724 125018856
CSEM103387459(csgalnact2) 103390413(csgalnact1) 103397716
POV109626572 109632851(csgalnact2) 109637154
SSEN122758252(csgalnact1a) 122769482 122781771(csgalnact2)
HHIP117768538 117772080(csgalnact1a) 117775771(csgalnact2)
HSP118115258 118118841(csgalnact2) 118125681(csgalnact1a)
PPLT128425036(csgalnact1a) 128438277 128453263(csgalnact2)
SMAU118283944(csgalnact2) 118285191(csgalnact1a) 118314573
LCF108874113 108882236 108886250
SDU111220601(csgalnact2) 111230915 111239886(csgalnact1)
SLAL111645131 111656793(csgalnact1) 111669464
XGL120796223(csgalnact2) 120805287 120806778(csgalnact1a)
HCQ109523133(csgalnact2) 109525674 109527907
SSCV125978803 125979560 125993729
SBIA133490665(csgalnact1a) 133509821(csgalnact2)
PEE133400580 133409549(csgalnact2) 133413602(csgalnact1a)
PTAO133465272(csgalnact1a) 133475208 133486221(csgalnact2)
BPEC110157439 110162232(csgalnact2) 110167048
MALB109956612 109960538(csgalnact2) 109972367
BSPL114842204(csgalnact2) 114862672 114866488(csgalnact1a)
SJO128364903 128372604(csgalnact2) 128380363(csgalnact1a)
SASA100380505(cgat2) 106561858 106568408 106580571 106604550
STRU115149376 115153006 115159173 115194009 115200434
OTW112219676 112252622 112252801(csgalnact2) 112259460 112262614
OMY110502269 110523911 110526347(csgalnact2) 110536326 110537010
OGO124000705 124019130 124035267 124038109 124041443(csgalnact2)
ONE115105966 115113391 115127070 115135311 115140299
OKI109868588 109889770 109892046 109895157 109899584
OKE118357949 118369503 118387888 118391522 118402085
SALP111951904 111958008 111961295 111978372 111980189
SNH120017519(csgalnact2) 120026423 120044206 120046459 120062799
CCLU121553676(csgalnact2) 121568834 121573494 121581872 121582833
ELS105014092 105026679(csgalnact1) 105028646(csgalnact2)
SFM108924956(csgalnact1) 108932703(csgalnact2)
PKI111849050(csgalnact2) 111849915(csgalnact1)
AANG118206747(csgalnact1b) 118212966(csgalnact1a) 118218071(csgalnact2)
LOC102686672(csgalnact2) 102694271(csgalnact1)
PSPA121304057(csgalnact1a) 121314225 121325711(csgalnact2)
ARUT117408808 117418452(csgalnact2) 117420659(csgalnact1a)
PSEX120527199(csgalnact1a) 120529200(csgalnact2)
LCM102358556(CSGALNACT2) 102366614(CSGALNACT1)
CMK103181211(csgalnact2) 103186731
RTP109912510(csgalnact2)
CPLA122539454 122541904(csgalnact2)
HOC132833350 132834922(csgalnact2)
LERI129701196 129712933(csgalnact2)
PMRN116956930
LRJ133359474
BFO118410920
BBEL109485484
CIN100177589
SCLV120346922 120346923
SPU579124
LPIC129281811
APLC110991016
AJC117123315
SKO100368195
DMEDmel_CG12913(Csgalnact)
DER6543177
DSE6608480
DSIDsimw501_GD10724(Dsim_GD10724)
DYADyak_GE19348
DAN6495632
DSR110178256
DPO4804207
DPE6590525
DMN108159923
DWI6646033
DGR6560215
DMODmoj_GI19322
DAZ108615801
DNV108653728
DHE111599136 115483363
DVI6625749
TDA119679725
ECOE129948994
CLON129611172
HIS119646653
AGA1269523
ACOZ120953354
AARA120893196
AMER121594790
ASTE118513612 118517283
AFUN125767271
AMOU128302003
AALI118465303
AAG5578232
AALB109398311 109419701
ASUA134208734
CQUCpipJ_CPIJ019283
CPII120425696
CNS116345176
BCOO119083657
NVI100121958
CSOL105364133
TPRE106650500
LHT122498055
LBD127287746
MDL103578840
CGLO123262930
FAS105268100
DAM107041616
AGIF122854813
CINS118064942
VCAN122409117
CCIN107270238
DSM124404876
NPT124215875
NFB124178283
NLO107225156
NVG124299932
AROA105690400
TCA659298
DPA109542837
SOY115886992
AGRG126733928
ATD109600607
CSET123314829
AGB108911720
LDC111503128
DVV126887302
NVL108559669
PPYR116163942
OTU111420233
CFEL113384842
CCRN123299712
BTAB109034694
CLEC112126951
HHAL106691779
NLU111056642
HVI124358995
MQU128988075
PHUPhum_PHUM567440
ZNE110838755
SGRE126284727 126317480
BROR134535534
IEL124160613 124160643
DPXDAPPUDRAFT_45221
DMK116932720
DPZ124350587
PVM113805822 113809704 113817038 113827476
PJA122247263 122253243 122257553 122264961
PCHN125030686 125036831 125037210 125046841
PMOO119572550 119588663 119591125
HAME121854961 121857077 121857246 121861079 121862361
PCLA123759046 123767688 123773851
CQD128688685 128697832
PTRU123508538 123509873
ESN126981975 126986577
MNZ135210266 135218300 135222851
HAZT108669553 108678155
PPOI119092469 119096825 119109726 119112165 119112629
CSCU111618117 111635148
PTEP107443124 107456076
ABRU129962101 129969547
UDV129220875 129224647
SDM118185560 118192927
LPOL106457953
LGILOTGIDRAFT_174094
PVUL126810810
PCAN112575074
BGT106055870
GAE121380061
HRF124142722
HRJ124275673
CRG105325571
CANU128166277
CVN111121591
OED125672055
MYI110456749
PMAX117330640
MCAF127707614
MMER123563253
RPHI132719622
DPOL127868010 127868067
MAEA128225193
OBI106881725
OSN115225312
LJP135469135
LAK106167613
LLON135483244
NVE5513641 5521813
EPA110234086 110241416 110249577
ATEN116298208 116299872
ADF107339026 107343332
AMIL114956205 114966420
PDAM113668297 113673292
SPIS111333179 111338037
DGT114517412
XEN124453566 124454147 124454656 124458086
HMG100201765 100209345
HSY130623941 130641080
RES135681318 135683170
AQU105313529
CCPCHC_T00008612001 CHC_T00008980001
SREPTSG_00810
 » show all
Reference
1  [PMID:3922754]
  Authors
Rohrmann K, Niemann R, Buddecke E.
  Title
Two N-acetylgalactosaminyltransferase are involved in the biosynthesis of chondroitin sulfate.
  Journal
Eur J Biochem 148:463-9 (1985)
DOI:10.1111/j.1432-1033.1985.tb08862.x
Reference
2  [PMID:11788602]
  Authors
Uyama T, Kitagawa H, Tamura Ji J, Sugahara K
  Title
Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
  Journal
J Biol Chem 277:8841-6 (2002)
DOI:10.1074/jbc.M111434200
  Sequence
[hsa:55790]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.174
IUBMB Enzyme Nomenclature: 2.4.1.174
ExPASy - ENZYME nomenclature database: 2.4.1.174
BRENDA, the Enzyme Database: 2.4.1.174
CAS: 96189-39-8
LinkDB

KEGG   REACTION: R05929
Entry
R05929                      Reaction                               
Definition
UDP-N-acetyl-D-galactosamine + G00157 <=> UDP + G00158
Equation
Enzyme
Pathway
rn00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
rn01100  Metabolic pathways
Module
M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.174
     R05929  UDP-N-acetyl-D-galactosamine + G00157 <=> UDP + G00158
Glycosyltransferase reactions [BR:br08203]
 N-Acetylgalactosaminyltransferase reactions
  R05929  GalNAc b1-4 GlcA
Orthology
K00746  chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175]
Other DBs
RHEA: 23467
LinkDB

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