Entry |
|
Symbol |
glmS, GFPT
|
Name |
glutamine---fructose-6-phosphate transaminase (isomerizing) [EC: 2.6.1.16]
|
Pathway |
map00250 | Alanine, aspartate and glutamate metabolism |
map00520 | Amino sugar and nucleotide sugar metabolism |
map01250 | Biosynthesis of nucleotide sugars |
|
Module |
M00892 | UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc |
M00909 | UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc |
M00995 | UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc |
M01002 | UDP-GalNAc biosynthesis, Fru-6P => UDP-GalNAc |
|
Reaction |
R00768 | L-glutamine:D-fructose-6-phosphate isomerase (deaminating) |
|
Disease |
H00770 | Congenital myasthenic syndrome |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
09160 Human Diseases
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
09167 Endocrine and metabolic disease
04931 Insulin resistance
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
Enzymes [BR:ko01000]
2. Transferases
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.16 glutamine---fructose-6-phosphate transaminase (isomerizing)
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
Family C44
K00820 glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing)
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
McKnight GL, Mudri SL, Mathewes SL, Traxinger RR, Marshall S, Sheppard PO, O'Hara PJ |
Title |
Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. |
Journal |
J Biol Chem 267:25208-12 (1992) |
Sequence |
|
Reference |
|
Authors |
Oki T, Yamazaki K, Kuromitsu J, Okada M, Tanaka I |
Title |
cDNA cloning and mapping of a novel subtype of glutamine:fructose-6-phosphate amidotransferase (GFAT2) in human and mouse. |
Journal |
|
Reference |
|
Authors |
Teplyakov A, Obmolova G, Badet-Denisot MA, Badet B |
Title |
The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase. |
Journal |
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LinkDB |
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