Entry |
|
Symbol |
GCK
|
Name |
|
Pathway |
map00520 | Amino sugar and nucleotide sugar metabolism |
map00524 | Neomycin, kanamycin and gentamicin biosynthesis |
map01110 | Biosynthesis of secondary metabolites |
map01120 | Microbial metabolism in diverse environments |
map01250 | Biosynthesis of nucleotide sugars |
map04950 | Maturity onset diabetes of the young |
map05230 | Central carbon metabolism in cancer |
|
Module |
M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
M00549 | Nucleotide sugar biosynthesis, glucose => UDP-glucose |
M00892 | UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc |
|
Reaction |
R00299 | ATP:D-glucose 6-phosphotransferase |
R01600 | ATP:beta-D-glucose 6-phosphotransferase |
R01786 | ATP:alpha-D-glucose 6-phosphotransferase |
|
Disease |
H00410 | Maturity onset diabetes of the young (MODY) |
H00512 | Permanent neonatal diabetes mellitus |
H01267 | Familial hyperinsulinemic hypoglycemia |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K12407 GCK; glucokinase
00052 Galactose metabolism
K12407 GCK; glucokinase
00500 Starch and sucrose metabolism
K12407 GCK; glucokinase
00520 Amino sugar and nucleotide sugar metabolism
K12407 GCK; glucokinase
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
K12407 GCK; glucokinase
00524 Neomycin, kanamycin and gentamicin biosynthesis
K12407 GCK; glucokinase
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
K12407 GCK; glucokinase
04910 Insulin signaling pathway
K12407 GCK; glucokinase
04922 Glucagon signaling pathway
K12407 GCK; glucokinase
04917 Prolactin signaling pathway
K12407 GCK; glucokinase
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
K12407 GCK; glucokinase
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K12407 GCK; glucokinase
04950 Maturity onset diabetes of the young
K12407 GCK; glucokinase
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
K12407 GCK; glucokinase
|
Other DBs |
|
Genes |
» show all
|
Reference |
|
Authors |
Iynedjian PB |
Title |
Molecular physiology of mammalian glucokinase. |
Journal |
|
LinkDB |
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