Entry
Symbol
ARO1
Name
Pathway
map00400 Phenylalanine, tyrosine and tryptophan biosynthesis
map00999 Biosynthesis of various plant secondary metabolites
map01110 Biosynthesis of secondary metabolites
Module
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
Reaction
R02412 ATP:shikimate 3-phosphotransferase
R02413 shikimate:NADP+ 3-oxidoreductase
R03083 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (cyclyzing)
R03084 3-dehydroquinate hydro-lyase
R03460 phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
K13830 ARO1; pentafunctional AROM polypeptide
09110 Biosynthesis of other secondary metabolites
00999 Biosynthesis of various plant secondary metabolites
K13830 ARO1; pentafunctional AROM polypeptide
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.25 shikimate dehydrogenase (NADP+)
K13830 ARO1; pentafunctional AROM polypeptide
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase
K13830 ARO1; pentafunctional AROM polypeptide
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.71 shikimate kinase
K13830 ARO1; pentafunctional AROM polypeptide
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.10 3-dehydroquinate dehydratase
K13830 ARO1; pentafunctional AROM polypeptide
4.2.3 Acting on phosphates
4.2.3.4 3-dehydroquinate synthase
K13830 ARO1; pentafunctional AROM polypeptide
BRITE hierarchy
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Genes
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Taxonomy UniProt
Reference
Authors
Duncan K, Edwards RM, Coggins JR
Title
The pentafunctional arom enzyme of Saccharomyces cerevisiae is a mosaic of monofunctional domains.
Journal
Sequence
LinkDB
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