KEGG   ORTHOLOGY: K01197
Entry
K01197                      KO                                     
Symbol
hya
Name
hyaluronoglucosaminidase [EC:3.2.1.35]
Pathway
map00531  Glycosaminoglycan degradation
map01100  Metabolic pathways
map04142  Lysosome
Module
M00076  Dermatan sulfate degradation
M00077  Chondroitin sulfate degradation
Disease
H00133  Mucopolysaccharidosis type IX
H00421  Mucopolysaccharidosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K01197  hya; hyaluronoglucosaminidase
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K01197  hya; hyaluronoglucosaminidase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K01197  hya; hyaluronoglucosaminidase
   00536 Glycosaminoglycan binding proteins
    K01197  hya; hyaluronoglucosaminidase
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K01197  hya; hyaluronoglucosaminidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     K01197  hya; hyaluronoglucosaminidase
Bacterial toxins [BR:ko02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   K01197  hya; hyaluronoglucosaminidase
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Enzymes
   K01197  hya; hyaluronoglucosaminidase
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Enzymes
  K01197  hya; hyaluronoglucosaminidase
Other DBs
RN: R07824 R07825 R10905
GO: 0004415
CAZy: GH56
Genes
HSA: 23553(HYAL4) 3373(HYAL1) 6677(SPAM1) 8372(HYAL3) 8692(HYAL2)
PTR: 460389(HYAL3) 460390(HYAL1) 460391(HYAL2) 472497(HYAL4) 472498(SPAM1) 738764
PPS: 100975669(HYAL2) 100976003(HYAL1) 100976800(HYAL3) 100979818 100980408(SPAM1) 100989231
GGO: 101123757 101123816(HYAL2) 101150470 101150849(SPAM1) 101151269(HYAL1) 101152349(HYAL3)
PON: 100453650(HYAL2) 100455010(HYAL1) 100455370(HYAL3) 100458070 100461750 100462117(SPAM1)
NLE: 100582240 100582343 100582574(SPAM1) 100590133(HYAL3) 100591153(HYAL1) 100592159(HYAL2)
MCC: 106996913(HYAL3) 696128 696249(SPAM1) 696805(HYAL4) 702484(HYAL2) 702850(HYAL1)
MCF: 101926741(SPAM1) 102119956 102120586(HYAL4) 102141387(HYAL1) 102146623(HYAL2) 107126372(HYAL3)
CSAB: 103226818 103226819 103226820(SPAM1) 103227668(HYAL1) 103227669 103227673(HYAL2)
CATY: 105573720(HYAL3) 105573721(HYAL1) 105573722(HYAL2) 105598514 105598515 105598516(SPAM1)
TGE: 112618329(HYAL2) 112618852(HYAL3) 112619564(HYAL1) 112620985(SPAM1) 112621266 112621682
RRO: 104666011(HYAL4) 104666012(SPAM1) 104666017 104666991(HYAL2) 104667013(HYAL1) 104667040(HYAL3)
RBB: 108523239(SPAM1) 108523241 108523242(HYAL4) 108526954(HYAL2) 108526956(HYAL1) 108526957(HYAL3)
TFN: 117073069(SPAM1) 117073109 117073115 117081845(HYAL1) 117081891(HYAL3) 117081976(HYAL2)
PTEH: 111550204 111550228(SPAM1) 111550243(HYAL4) 111555346(HYAL3) 111555348(HYAL1) 111555415(HYAL2)
CJC: 100405923(HYAL1) 100406523(HYAL3) 100407141(HYAL2) 100410718(SPAM1) 100411084(HYAL4)
SBQ: 101036461 101037627(HYAL2) 101039509(HYAL1) 101040064(HYAL3) 101053467(SPAM1) 101053778(HYAL4)
OGA: 100948773(HYAL3) 100955014 100955323 100955966 100963152(HYAL1) 100963472(HYAL2) 100965936(HYAL4) 111725318(SPAM1)
MMU: 109685(Hyal3) 15586(Hyal1) 15587(Hyal2) 20690(Spam1) 74409(Hyal6) 74468(Hyal5) 77042(Hyal4)
RNO: 117037(Spam1) 300993(Hyal3) 367166(Hyal1) 404783(Hyal4) 500051(Hyal6) 500052(Hyal5) 64468(Hyal2)
HGL: 101700218(Spam1) 101701149(Hyal1) 101701738(Hyal3) 101709759(Hyal2) 101723286(Hyal4) 101723647
CPOC: 100135624(Spam1) 100713959(Hyal4) 100716200(Hyal1) 100716485(Hyal2) 100724497 101789144(Hyal3)
DSP: 122095747(Hyal2) 122095748(Hyal1) 122095751(Hyal3) 122121740(Hyal4) 122121764 122121765(Spam1) 122121869
OCU: 100009375(HYAL2) 100009391(SPAM1) 100337723 100337977 100339482(HYAL3) 100339732(HYAL1)
TUP: 102480682 102481108(SPAM1) 102481532(HYAL4) 102482361 102483390(HYAL2) 102484339(HYAL1) 102485187(HYAL3)
CFA: 475211(SPAM1) 475212(HYAL4) 484760(HYAL2) 608602(HYAL1) 608620(HYAL3) 609321
VVP: 112911070(HYAL2) 112911103(HYAL1) 112911108(HYAL3) 112935064(SPAM1) 112935090(HYAL4)
VLG: 121474528(HYAL4) 121474834(SPAM1) 121494796(HYAL3) 121495988(HYAL2) 121495989(HYAL1)
AML: 100470607(HYAL2) 100470685(SPAM1) 100472672 100481098(HYAL3) 109489578(HYAL4)
UMR: 103674798(HYAL2) 103674799(HYAL3) 103675086(HYAL1) 103676616 103676617(SPAM1) 103676687
UAH: 113256904(HYAL3) 113256907(HYAL2) 113256908(HYAL1) 113266534 113266542(SPAM1) 113266980(HYAL4)
UAR: 123789558(SPAM1) 123789675(HYAL4) 123798687(HYAL3) 123798691(HYAL1) 123798692(HYAL2)
MPUF: 101681380(HYAL4) 101683893(SPAM1) 101684068(HYAL2) 101684178 101684726(HYAL1) 101685538(HYAL3)
ORO: 101364702 101365006(SPAM1) 101366496 101369009(HYAL3) 101369610(HYAL1) 101370114(HYAL2)
EJU: 114210572 114210600 114210699(SPAM1) 114225044(HYAL3) 114225120(HYAL1) 114225130(HYAL2)
MLX: 118005108 118005305(HYAL3) 118021385(HYAL4) 118021386(SPAM1)
FCA: 101092920(HYAL3) 101093011 101094000(HYAL2) 101095484(HYAL4) 101095731(SPAM1)
PYU: 121011229(HYAL2) 121011234(HYAL3) 121028400(SPAM1) 121028401 121028402(HYAL4)
PBG: 122486473 122486474(HYAL4) 122487251(HYAL2) 122487254(HYAL3) 122488168(SPAM1)
PTG: 102964157 102964452(HYAL4) 102964738(SPAM1) 102965224(HYAL1) 102966380(HYAL3)
PPAD: 109247837 109247842(HYAL3) 109268920(HYAL4) 109268922(SPAM1) 109269038
AJU: 106970630(SPAM1) 106970631 106970632 106979259(HYAL3) 106979262(HYAL2)
BTA: 281838(HYAL2) 353352(SPAM1) 509761 515397(HYAL1) 518161(HYAL4) 527125 616562(HYAL3)
BOM: 102267588 102275599(HYAL3) 102275634 102275878(HYAL1) 102276163(HYAL2) 102284407(HYAL4) 102284688(SPAM1)
BIU: 109557586(HYAL4) 109557587(SPAM1) 109557935 109558119 109576069(HYAL2) 109576071(HYAL1) 109576073(HYAL3)
CHX: 100860748(PH-20) 102168417 102168691(SPAM1) 102172212(HYAL2) 102173238(HYAL1) 102189274(HYAL4)
OAS: 101101889 101102143 101106519(HYAL4) 101107188 101121207(HYAL1) 101121461(HYAL3) 443154(HYAL2)
ODA: 120868296(HYAL2) 120868299(HYAL1) 120868300(HYAL3) 120877304 120877537(HYAL4) 120877539
SSC: 100524837(HYAL4) 397074(SPAM1) 404696(HYAL3) 404697(HYAL2) 404698(HYAL1)
CFR: 102504111(SPAM1) 102504354 102521347(HYAL1) 102521929(HYAL3) 102522934
CBAI: 105063121(HYAL4) 105063220(SPAM1) 105063221 105080227(HYAL1) 105080231(HYAL3)
CDK: 105085347 105085422(HYAL4) 105085423(SPAM1) 105087442 105087477(HYAL3)
BACU: 103005390(HYAL3) 103006722(HYAL1) 103007213(HYAL2) 103009506(HYAL4) 103009600(SPAM1)
LVE: 103071921(HYAL3) 103072374(HYAL1) 103073012(HYAL2) 103082114(SPAM1) 103082392(HYAL4)
OOR: 101276998(HYAL3) 101277665(HYAL1) 101277905(HYAL2) 101281301(SPAM1) 101281553(HYAL4)
DLE: 111174361(HYAL2) 111174362(HYAL1) 111174363(HYAL3) 111182813(SPAM1) 111182819(HYAL4)
PCAD: 102981618(HYAL4) 102981903(SPAM1) 102995474(HYAL2) 102996103 102996374(HYAL3)
PSIU: 116759674(SPAM1) 116759784(HYAL4) 116762041 116762042(HYAL3)
ECB: 100051243(SPAM1) 100056514 100061845(HYAL2) 100061939(HYAL3) 106783049
EPZ: 103544212(SPAM1) 103557348(HYAL3) 103557349 103560648(HYAL4)
MYB: 102239190(HYAL1) 102249798(HYAL4) 102250717(HYAL3) 102251014(HYAL2) 102257934(SPAM1)
MYD: 102754556(HYAL3) 102754833(HYAL2) 102772512(HYAL1) 102773736(HYAL4) 102774302(SPAM1)
MMYO: 118665788(SPAM1) 118666450(HYAL4) 118668442(HYAL2) 118668452(HYAL3) 118668453(HYAL1)
MLF: 102421760(HYAL3) 102422075(HYAL2) 102423475(HYAL1) 102423485(HYAL4) 102430111(SPAM1)
MNA: 107537310(SPAM1) 107537332(HYAL4) 107545075(HYAL3) 107545081(HYAL2) 107545082(HYAL1)
PKL: 118712176(HYAL4) 118714542(SPAM1) 118714544 118715639(HYAL2) 118715642(HYAL1) 118715643(HYAL3)
HAI: 109372568(SPAM1) 109372572(HYAL4) 109375181(HYAL3) 109375791(HYAL2) 109375816(HYAL1)
DRO: 112299724(SPAM1) 112299918(HYAL4) 112309830(HYAL2) 112309908(HYAL1) 112309979(HYAL3)
SHON: 118989443(HYAL2) 118989449 118989450(HYAL3) 118993967(SPAM1) 118993968(HYAL4) 118998538
AJM: 119036627(HYAL1) 119036629(HYAL3) 119036683(HYAL2) 119041988 119065606(HYAL4) 119065607(SPAM1)
PDIC: 114501414(HYAL2) 114501418 114507228(SPAM1) 114507240(HYAL4)
PHAS: 123823850(HYAL4) 123829729(SPAM1) 123830501(HYAL1) 123830714(HYAL3) 123830860(HYAL2)
MMF: 118619686(SPAM1) 118620423(HYAL4) 118632990(HYAL3) 118633150(HYAL1) 118633201(HYAL2)
RFQ: 117017998(HYAL4) 117018077(SPAM1) 117036739(HYAL1) 117036741(HYAL3) 117037138(HYAL2)
PALE: 102878728(HYAL3) 102878975(HYAL1) 102879396(HYAL2) 102891124(SPAM1) 102891363(HYAL4)
PGIG: 120582382(HYAL2) 120582383(HYAL3) 120582385(HYAL1) 120601060(SPAM1) 120601119(HYAL4)
PVP: 105290167(HYAL4) 105290226(SPAM1) 105295147(HYAL2) 105295148(HYAL1) 105295149(HYAL3)
RAY: 107500196(SPAM1) 107500203(HYAL4) 107513380(HYAL3) 107513383(HYAL2) 107513385(HYAL1)
MJV: 108392261(SPAM1) 108402857(HYAL2) 108402859(HYAL1) 108402860(HYAL3)
LAV: 100661612(HYAL4) 100667479(SPAM1) 100669188(HYAL2) 100669471(HYAL1)
MDO: 100016989 100017029(HYAL4) 100017190(SPAM1) 100028570(HYAL3) 100028614(HYAL1) 100028633(HYAL2) 100031013 107648899
OAA: 100076538 100076578(SPAM1) 100078017(HYAL1) 100078126(HYAL2) 100681427(HYAL3)
GGA: 100859903(HYAL3) 105667218(HYAL6) 415908(HYAL2) 417749(SPAM1) 426739(HYAL1)
PCOC: 116232293(HYAL2) 116232317(HYAL1) 116241049(HYAL3) 116243730 116244297(SPAM1)
MGP: 100541798(SPAM1) 100541954 100542084(HYAL1) 100542238(HYAL2) 104909302
CJO: 107308697 107308927 107319561(HYAL2) 107319564(HYAL1) 107319647(HYAL3)
NMEL: 110392510(HYAL4) 110392545(SPAM1) 110392602 110404867(HYAL2) 110404888(HYAL3) 110404973(HYAL1)
APLA: 101795794(HYAL1) 101799098 101799286 101800183(HYAL2) 106014259(SPAM1)
ACYG: 106042799 106047618(HYAL4) 106047621(SPAM1) 106047623
AFUL: 116493100(HYAL1) 116493101(HYAL2) 116493105(HYAL3) 116498436(SPAM1) 116501953
LSR: 110469962(HYAL1) 110469963(HYAL2) 110472582(HYAL3) 110483505 110483513
SCAN: 103813480(SPAM1) 103813696 103816969(HYAL2) 103817140(HYAL1) 103824300(HYAL3)
PMOA: 120510742 120510758(SPAM1) 120513985(HYAL2) 120513987(HYAL1) 120514049(HYAL3)
OTC: 121336367 121336371 121347107(HYAL2) 121347108(HYAL1) 121347271(HYAL3)
PRUF: 121351109(HYAL3) 121352862(HYAL2) 121352879(HYAL1) 121355777 121355815
GFR: 102035392(HYAL3) 102037819(SPAM1) 102042845 102043012(HYAL4) 102044902(HYAL2) 102045068(HYAL1)
FAB: 101807037(HYAL3) 101808121(HYAL4) 101808315 101816626(SPAM1) 101820358(HYAL2) 101820552(HYAL1)
PHI: 102101272(HYAL1) 102105429(HYAL3) 102111253(SPAM1) 102112351(HYAL2) 102114472(HYAL4)
CCAE: 111922967 111922968(SPAM1) 111935139(HYAL3) 111935185(HYAL1) 111935321(HYAL2)
CCW: 104683216(HYAL1) 104683435(HYAL2) 104686823(SPAM1) 104686903(HYAL4) 120410683(HYAL3)
ETL: 114058671(HYAL3) 114058776(HYAL1) 114058796(HYAL2) 114062855(SPAM1) 114062856(HYAL4)
FPG: 101911022(HYAL3) 101919114(SPAM1) 101919242(HYAL1) 101919279(HYAL4) 101919413(HYAL2) 101919451
EGZ: 104125665 104125689(SPAM1) 104126661 104126687(HYAL1) 104126688(HYAL2)
NNI: 104008686(HYAL3) 104008712(HYAL1) 104008746(HYAL2) 104011818(SPAM1) 104011835
ACUN: 113484688(HYAL3) 113484799 113484915(HYAL2) 113491205(SPAM1) 113491527
TALA: 104358014 104358015(HYAL4) 104358016 116959464(HYAL1) 116959470(HYAL2) 116959511(HYAL3)
ACHC: 115333336(HYAL1) 115333400(HYAL2) 115341419(SPAM1) 115341420 115341421(HYAL4) 115353738
NPD: 112953047(HYAL1) 112953106(HYAL2) 112953196(HYAL3) 112957912(SPAM1) 112957919
ASN: 102378863(HYAL1) 102379112(HYAL2) 102383208(HYAL3) 102384522 102384773 112550426(SPAM1)
AMJ: 102557643(HYAL3) 102574610 102574830(HYAL1) 102574839(HYAL4) 102575064(HYAL2) 109284220(SPAM1)
CPOO: 109315652 109315653 109315654(SPAM1) 109318255(HYAL3) 109318290(HYAL1) 109318293(HYAL2)
TST: 117867584(HYAL4) 117867976(SPAM1) 117868042 117880336(HYAL3) 117880389(HYAL2) 117880552(HYAL1) 117880875
XLA: 100337508(hyal2.L) 108711150(hyal4.L) 108714598(hyal1.L) 380470(hyal2.S) 398285(spam1.L)
XTR: 100037890(hyal4) 100144942(hyal2) 100486024(spam1) 100498156(hyal1)
BBUF: 120979665(HYAL2) 120979669 120981997(HYAL4) 120985762
DRE: 100004557(hyal3) 108181664 559228(hyal2b) 562480(si:dkey-72l14.3) 567869(hyal2a) 664772(hyal1) 791189(hyal6) 791203(spam1)
IPU: 108254948(hyal2b) 108265127(si:dkey-72l14.3) 108265970 108271980(hyal1) 108271981(hyal2a) 108274420 108274445 108274446 108274447
SMEO: 124375255(hyal2a) 124391300(hyal1) 124392619 124392928 124392929 124399529(si:dkey-72l14.3) 124400362(hyal3) 124402448(hyal2b)
ELY: 117249512 117256184(hyal2b) 117256514(hyal1) 117257535(hyal2a) 117257652(hyal3) 117258506(si:dkey-72l14.3) 117262216 117262217 117262218(hyal6) 117262220
PLEP: 121938119 121947267(hyal3) 121947572(si:dkey-72l14.3) 121949693 121949695(hyal6) 121949696 121950021(hyal1) 121958158(hyal2a) 121958649(hyal2b) 121961602
SLUC: 116036273 116036275(hyal6) 116036281 116036282 116040834(si:dkey-72l14.3) 116041583(hyal2b) 116051546(hyal2a) 116051573(hyal1) 116060200
ECRA: 117938381 117942979(hyal2a) 117942981(hyal1) 117943903(hyal2b) 117947740(si:dkey-72l14.3) 117949729 117949730(hyal6) 117949735 117949736
GAT: 120808725(hyal6) 120809717(spam1) 120809729 120829318(si:dkey-72l14.3) 120834688(hyal1) 120834689(hyal2a) 120835813(hyal2b)
PPUG: 119194093(hyal2b) 119194133(hyal1) 119194269(hyal2a) 119195475 119195476(hyal6) 119195477(spam1) 119199516(si:dkey-72l14.3) 119204549 119222161(hyal3)
MSAM: 119886008(hyal2b) 119886251(hyal2a) 119886252(hyal1) 119893097 119893176(hyal6) 119894110 119894190 119905714(hyal3) 119905727(si:dkey-72l14.3) 119917927
CUD: 121505799 121506821(abhd14a) 121507060(hyal2a) 121507236(hyal1) 121511380 121514550 121514809 121515413 121515684(hyal6) 121517137(hyal3) 121517852(si:dkey-72l14.3)
OAU: 116309822 116313670(hyal2b) 116319262(hyal6) 116319280 116324686(si:dkey-72l14.3) 116324701(hyal3) 116334260(hyal1) 116334277(hyal2a) 120440909
OML: 112141244(spam1) 112141252(hyal6) 112141264 112144497(hyal1) 112145762(hyal2a) 112145774(hyal2b) 112159355(si:dkey-72l14.3) 112159636(hyal3)
GAF: 122830251(si:dkey-72l14.3) 122831723(hyal3) 122833793(hyal1) 122834194 122834509 122834513 122836089(spam1) 122836090 122836091(hyal6)
CTUL: 119775067(hyal1) 119775110(hyal2a) 119777771(hyal6) 119777772 119777773 119777774 119779982(hyal2b) 119789079(si:dkey-72l14.3) 119789236(hyal3)
KMR: 108231210(hyal2a) 108231224(hyal1) 108233042(hyal3) 108233059(si:dkey-72l14.3) 108247372(hyal2b) 108247453(hyal6) 108247456 108247457 108247463
NWH: 119412378(hyal2a) 119412470(hyal2b) 119412768(hyal1) 119415862 119415864(hyal6) 119415867(spam1) 119417696(si:dkey-72l14.3) 119417703(hyal3)
SSEN: 122757973 122767243 122768687(hyal2b) 122768762(hyal1) 122768854(hyal2a) 122776000 122776001 122776002 122776522(hyal6) 122776631(hyal3) 122777404(si:dkey-72l14.3)
HHIP: 117757514 117761138(hyal2b) 117761537(hyal2a) 117761538(hyal1) 117763086(hyal6) 117763491 117763637 117763722 117764188(hyal3) 117764707(si:dkey-72l14.3)
XGL: 120783132(hyal2b) 120783278(hyal2a) 120783445(hyal1) 120793315 120793452 120793457(hyal6) 120793461 120803875 120804171(hyal3) 120804522(si:dkey-72l14.3)
AANG: 118207978(si:dkey-72l14.3) 118208324(hyal2a) 118208389(hyal3) 118208668(hyal1) 118211859(hyal2b) 118231418 118231471(hyal6) 118231864 118232068 118232069(spam1)
CIN: 100186831
SKO: 100377225
ACOZ: 120958015
AARA: 120902874
AAG: 5578235
CNS: 116340278
AME: 406146
ACER: 107998690
BIM: 100743050
BBIF: 117214033
BVK: 117242244
BVAN: 117155064
BTER: 100651053
BPYO: 122574566
CCAL: 108623515
OBB: 114874207
MGEN: 117226235
NMEA: 116427063
CGIG: 122402040
SOC: 105196779
MPHA: 105831859
AEC: 105148714
ACEP: 105623333
PBAR: 105426307
HST: 105188713
DQU: 106745903
CFO: 105251112
FEX: 115246141
LHU: 105669752
PGC: 109856266
OBO: 105284697
PCF: 106786428
PFUC: 122526363
NVI: 100115714
CSOL: 105365060
MDL: 106694078
FAS: 105265723
DAM: 107039604
AGIF: 122848107
CCIN: 107267958
TCA: 661685
DPA: 109537076
SOY: 115881634
CSET: 123320374
AGB: 108916042
LDC: 111505889
NVL: 108567699
APLN: 108739604
OTU: 111424977
BMOR: 101735594
BMAN: 114246843
MSEX: 115444614
BANY: 112054776
PXU: 106118667
PRAP: 111001369
ZCE: 119836628
HAW: 110371171
TNL: 113499184
OFU: 114358255
API: 100166159
DNX: 107173173
AGS: 114123047
RMD: 113549824
BTAB: 109042515
HHAL: 106692488
FOC: 113205517
PVM: 113823457
PJA: 122251479
PCLA: 123775274
PTRU: 123501587
HAZT: 108669953
PTEP: 107451035
CEL: CELE_T22C8.2(chhy-1)
CBR: CBG_00535(Cbr-chhy-1)
BGT: 106057545
MYI: 110450217
PMAX: 117345040
DGT: 114518013
XEN: 124444472
HMG: 100204026
XCC: XCC2028
XCB: XC_2155
XCP: XCR_2312
XCV: XCV4043
XAX: XACM_3822
XAC: XAC3928
XOM: XOO0189(XOO0189)
XOO: XOO0215(Chb)
XOP: PXO_03654
XOR: XOC_4258
XPH: XppCFBP6546_14760(XppCFBP6546P_14760)
MAQ: Maqu_3474
MHC: MARHY3369
MAD: HP15_3245
MARJ: MARI_31840
CJA: CJA_1347(hyl84)
GAI: IMCC3135_00340(nagJ)
AHA: AHA_1474
ASA: ASA_2891
AVR: B565_2712
AMED: B224_3724
AEL: NCTC12917_01334(nagJ)
PLA: Plav_1649
STAX: MC45_11905
SPHI: TS85_03725
SMIC: SmB9_36690
PPY: PPE_00341
PPM: PPSC2_01915(hyl)
PPO: PPM_0365(hyl)
PPOL: X809_01520
PPOY: RE92_10015
PLV: ERIC2_c20510(nagJ)
SPY: SPy_0701(hylP1) SPy_1600
SPZ: M5005_Spy1314(hyl)
SPYM: M1GAS476_1381(hyl)
SPYA: A20_1348c(hyl)
SPM: spyM18_0770(hylP) spyM18_1606(hyl)
SPG: SpyM3_0929(hylP.2) SpyM3_1214(hylP.4) SpyM3_1294(hyl)
SPJ: MGAS2096_Spy1334(hyl)
SPB: M28_Spy1355(hyl)
SOZ: Spy49_1236c(hyl)
SEZ: Sez_1507(hylZ)
SEQ: SZO_04490
SEZO: SeseC_02032(hya)
SEQU: Q426_01285
SEU: SEQ_1693
SDS: SDEG_1588(hyl)
SDA: GGS_1455(hyl)
SDC: SDSE_1739(hyl)
SDQ: SDSE167_1709(hyl)
SCAI: NCTC12191_01152(hyl)
EFU: HMPREF0351_12988(hyl)
CML: BN424_3030(hyl)
CARC: NY10_1498
CPR: CPR_1248
CBV: U729_414
AACX: DEACI_2673
TSH: Tsac_2289
APR: Apre_0148
MNU: NCTC10166_00357(nagH)
MCY: MCYN_0715(MCYN0715)
CCYC: SCMU_00620
SGR: SGR_4877
SGB: WQO_11075
SVE: SVEN_2438
SALS: SLNWT_7238
SFI: SFUL_2231
STRM: M444_12985
SLE: sle_45640(sle_45640)
SRN: A4G23_01727(nagJ)
STRD: NI25_36120
SLAU: SLA_2333
SALJ: SMD11_4482(hya)
SFK: KY5_2790
KSK: KSE_54890
ARX: ARZXY2_3886(hya)
LMOI: VV02_00325
CACN: RN83_03935
KFL: Kfla_3229
AOI: AORI_3373(hya)
AMYY: YIM_20355(nagJ)
AORI: SD37_17520
KAL: KALB_2454
ACTI: UA75_14920
ACAD: UA74_14330
AHG: AHOG_13470(nagJ)
SNA: Snas_2451
AHW: NCTC11636_02503(nagJ)
ASLA: NCTC11923_01310(nagJ)
BBP: BBPR_1635
BBI: BBIF_1576
BBF: BBB_1610(nagH)
AMR: AM1_0334
TTR: Tter_0116
AMU: Amuc_0052
AGL: PYTT_0357
BTH: BT_4395
BFR: BF4022
BVU: BVU_2069
PDI: BDI_1142
CPI: Cpin_5708
ZPR: ZPR_3254
PMO: Pmob_0472
DTN: DTL3_1494
SMR: Smar_0708
VG: 1257872(hylP.4) 4818462(phi3396_48) 5758581(P9_gp43) 929275(phiNIH1.1_p45)
 » show all
Reference
PMID:9712871
  Authors
Lepperdinger G, Strobl B, Kreil G
  Title
HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity.
  Journal
J Biol Chem 273:22466-70 (1998)
DOI:10.1074/jbc.273.35.22466
  Sequence
[hsa:8692]
Reference
  Authors
Lokeshwar VB, Schroeder GL, Carey RI, Soloway MS, Iida N
  Title
Regulation of hyaluronidase activity by alternative mRNA splicing.
  Journal
J Biol Chem 277:33654-63 (2002)
DOI:10.1074/jbc.M203821200
  Sequence
[hsa:8372]
Reference
  Authors
Kaneiwa T, Mizumoto S, Sugahara K, Yamada S
  Title
Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic linkage in the trisulfated tetrasaccharide sequence.
  Journal
Glycobiology 20:300-9 (2010)
DOI:10.1093/glycob/cwp174
  Sequence
[hsa:23553]
Reference
PMID:8282124
  Authors
Gmachl M, Sagan S, Ketter S, Kreil G
  Title
The human sperm protein PH-20 has hyaluronidase activity.
  Journal
FEBS Lett 336:545-8 (1993)
DOI:10.1016/0014-5793(93)80873-s
  Sequence
[hsa:6677]
LinkDB

KEGG   ENZYME: 3.2.1.35
Entry
EC 3.2.1.35                 Enzyme                                 
Name
hyaluronoglucosaminidase;
hyaluronidase;
hyaluronoglucosidase;
chondroitinase;
chondroitinase I
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
hyaluronate 4-glycanohydrolase
Reaction(IUBMB)
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate
Reaction(KEGG)
(other) R07824(G) R07825(G) R10905(G)
Comment
Also hydrolyses 1,4-beta-D-glycosidic linkages between N-acetyl-galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan.
History
EC 3.2.1.35 created 1965, modified 1976, modified 2001 (EC 3.2.1.34 created 1965, incorporated 1972)
Pathway
ec00531  Glycosaminoglycan degradation
ec01100  Metabolic pathways
Orthology
K01197  hyaluronoglucosaminidase
K19031  cell migration-inducing and hyaluronan-binding protein
K22144  cell surface hyaluronidase
Genes
HSA23553(HYAL4) 23670(CEMIP2) 3373(HYAL1) 57214(CEMIP) 6677(SPAM1) 8372(HYAL3) 8692(HYAL2)
PTR453585(CEMIP) 460389(HYAL3) 460390(HYAL1) 460391(HYAL2) 464523(CEMIP2) 472497(HYAL4) 472498(SPAM1) 738764
PPS100973013(CEMIP) 100975669(HYAL2) 100976003(HYAL1) 100976800(HYAL3) 100979818 100980408(SPAM1) 100989231 100992689(CEMIP2)
GGO101123757 101123816(HYAL2) 101130227(CEMIP) 101130666(CEMIP2) 101150470 101150849(SPAM1) 101151269(HYAL1) 101152349(HYAL3)
PON100441244(CEMIP) 100441700(CEMIP2) 100453650(HYAL2) 100455010(HYAL1) 100455370(HYAL3) 100458070 100461750 100462117(SPAM1)
NLE100581375(CEMIP2) 100582240 100582343 100582574(SPAM1) 100590133(HYAL3) 100591153(HYAL1) 100592159(HYAL2) 100601667(CEMIP)
MCC106996913(HYAL3) 696128 696249(SPAM1) 696805(HYAL4) 702484(HYAL2) 702850(HYAL1) 703378(CEMIP2) 717880(CEMIP)
MCF101926741(SPAM1) 102119956 102120586(HYAL4) 102129860 102135597(CEMIP2) 102141387(HYAL1) 102146623(HYAL2) 107126372(HYAL3)
CSAB103219570(TMEM2) 103226818 103226819 103226820(SPAM1) 103227668(HYAL1) 103227669 103227673(HYAL2) 103245218(CEMIP)
CATY105571482(CEMIP) 105573720(HYAL3) 105573721(HYAL1) 105573722(HYAL2) 105584167(TMEM2) 105598514 105598515 105598516(SPAM1)
PANU101001973 101002668 101003017 101004523(CEMIP2) 101006926(HYAL2) 101007869(HYAL1) 101008913(HYAL3) 101015715(CEMIP) 116274477 116274478 116274479 116274482 116274483 116274484
TGE112608170(CEMIP2) 112618329(HYAL2) 112618852(HYAL3) 112619564(HYAL1) 112620985(SPAM1) 112621266 112621682 112627965(CEMIP)
RRO104666011(HYAL4) 104666012(SPAM1) 104666017 104666991(HYAL2) 104667013(HYAL1) 104667040(HYAL3) 104672135(CEMIP2) 104678101(CEMIP)
RBB108522869(TMEM2) 108523239(SPAM1) 108523241 108523242(HYAL4) 108526954(HYAL2) 108526956(HYAL1) 108526957(HYAL3) 108538642(CEMIP)
TFN117070292(CEMIP) 117073069(SPAM1) 117073109 117073115 117081845(HYAL1) 117081891(HYAL3) 117081976(HYAL2) 117098477(CEMIP2)
PTEH111527190(CEMIP) 111543346(CEMIP2) 111550204 111550228(SPAM1) 111550243(HYAL4) 111555346(HYAL3) 111555348(HYAL1) 111555415(HYAL2)
CJC100405923(HYAL1) 100406523(HYAL3) 100406710(CEMIP) 100407141(HYAL2) 100410718(SPAM1) 100410994(TMEM2) 100411084(HYAL4)
SBQ101031601(TMEM2) 101033104(CEMIP) 101036461 101037627(HYAL2) 101039509(HYAL1) 101040064(HYAL3) 101053467(SPAM1) 101053778(HYAL4)
CSYR103250470(TMEM2) 103255457(HYAL2) 103255459(HYAL1) 103255460(HYAL3) 103256127 103256263(CEMIP) 103259411 103259412 103259413(SPAM1) 103273066
MMUR105864418(CEMIP) 105869919 105869923 105869925(HYAL4) 105874779(TMEM2) 105874994(HYAL3) 105874997(HYAL1) 105874999(HYAL2) 105884793 105884814 109729195
OGA100948773(HYAL3) 100952367(CEMIP) 100955014 100955323 100955966 100963152(HYAL1) 100963472(HYAL2) 100965347(TMEM2) 100965936(HYAL4) 111725318(SPAM1)
MMU109685(Hyal3) 15586(Hyal1) 15587(Hyal2) 20690(Spam1) 74409(Hyal6) 74468(Hyal5) 77042(Hyal4) 80982(Cemip) 83921(Cemip2)
MCAL110285460(Tmem2) 110296441 110296479 110296548 110297024 110297777(Cemip) 110301316(Hyal1) 110301317(Hyal3) 110301550(Hyal2)
MPAH110317111 110317225 110317269 110317392 110317795(Cemip) 110327584(Hyal1) 110327585(Hyal3) 110327750(Hyal2) 110337442(Tmem2)
RNO117037(Spam1) 300993(Hyal3) 308797(Cemip) 309400(Cemip2) 367166(Hyal1) 404783(Hyal4) 500051(Hyal6) 500052(Hyal5) 64468(Hyal2)
MCOC116072061(Hyal1) 116072064(Hyal3) 116073297(Hyal2) 116098025 116098026(Hyal4) 116098027 116098028 116102519(Cemip) 116103658(Cemip2)
MUN110549539 110549540(Spam1) 110549545 110549546 110549547 110554593(Cemip) 110562249(Tmem2) 110564337(Hyal1) 110564648(Hyal2) 110564669(Hyal3)
CGE100752414(Hyal2) 100752718(Hyal1) 100753318(Hyal3) 100758272 100759479(Cemip2) 100759710 100759996 100760289 100760429(Cemip)
PLEU114695583 114695593 114695616 114695617 114695618 114696234 114709898(Cemip2) 114710977(Hyal1) 114710978(Hyal3) 114710989(Hyal2)
NGI103727085 103727093 103727094 103727095 103741840(Tmem2) 103750156(Hyal2) 103750159(Hyal3) 103750160(Hyal1) 103750346(Cemip)
HGL101700218(Spam1) 101701149(Hyal1) 101701738(Hyal3) 101709759(Hyal2) 101712540(Tmem2) 101714296(Cemip) 101723286(Hyal4) 101723647
CPOC100135624(Spam1) 100713959(Hyal4) 100716200(Hyal1) 100716485(Hyal2) 100720639(Cemip) 100724497 100727128(Tmem2) 101789144(Hyal3)
CCAN109681133 109681134 109693216(Hyal2) 109693223(Hyal1) 109693227(Hyal3) 109697213(Tmem2) 109697496(Cemip) 109702494 109702496
DORD105982275(Cemip) 105987198(Tmem2) 105988318 105988319 105988321 105988371(Hyal4) 105994528(Hyal2) 105994548(Hyal1) 105994629(Hyal3)
DSP122095747(Hyal2) 122095748(Hyal1) 122095751(Hyal3) 122102021 122121740(Hyal4) 122121764 122121765(Spam1) 122121869 122124679(Cemip2)
OCU100009375(HYAL2) 100009391(SPAM1) 100337723 100337977 100339482(HYAL3) 100339732(HYAL1) 100343109(TMEM2) 100353125(CEMIP)
OPI101516685 101516754 101516933 101517180(SPAM1) 101517226(HYAL3) 101517468(HYAL2) 101522899 101533517(CEMIP2) 105941607
TUP102480682 102481108(SPAM1) 102481532(HYAL4) 102482361 102483390(HYAL2) 102484339(HYAL1) 102484391(CEMIP) 102485187(HYAL3) 102499468(TMEM2)
CFA475211(SPAM1) 475212(HYAL4) 484171(CEMIP2) 484760(HYAL2) 488766(CEMIP) 608602(HYAL1) 608620(HYAL3) 609321
VVP112911070(HYAL2) 112911103(HYAL1) 112911108(HYAL3) 112921114(CEMIP) 112922109(CEMIP2) 112935064(SPAM1) 112935090(HYAL4)
VLG121474528(HYAL4) 121474834(SPAM1) 121484624(CEMIP2) 121489849 121494796(HYAL3) 121495988(HYAL2) 121495989(HYAL1)
AML100465816(CEMIP2) 100467994 100470607(HYAL2) 100470685(SPAM1) 100472672 100481098(HYAL3) 109489578(HYAL4)
UMR103660291(CEMIP) 103663256(TMEM2) 103674798(HYAL2) 103674799(HYAL3) 103675086(HYAL1) 103676616 103676617(SPAM1) 103676687
UAH113256904(HYAL3) 113256907(HYAL2) 113256908(HYAL1) 113263774(CEMIP) 113266534 113266542(SPAM1) 113266980(HYAL4) 113270218(CEMIP2)
UAR123776556(CEMIP2) 123789558(SPAM1) 123789675(HYAL4) 123798687(HYAL3) 123798691(HYAL1) 123798692(HYAL2) 123802429
ELK111143952 111144050 111144346 111151847 111151911 111151913 111152116 111152634 111153557
MPUF101679606(CEMIP) 101681380(HYAL4) 101683893(SPAM1) 101684068(HYAL2) 101684178 101684726(HYAL1) 101685538(HYAL3) 101693901(TMEM2)
ORO101364702 101365006(SPAM1) 101366496 101369009(HYAL3) 101369610(HYAL1) 101370114(HYAL2) 101376897(TMEM2) 101382154(CEMIP)
EJU114197883(CEMIP2) 114198133(CEMIP) 114210572 114210600 114210699(SPAM1) 114225044(HYAL3) 114225120(HYAL1) 114225130(HYAL2)
ZCA113909733 113911486(SPAM1) 113911590 113912009 113916400(HYAL3) 113918067 113934288(CEMIP2)
MLX118005108 118005305(HYAL3) 118021385(HYAL4) 118021386(SPAM1) 118023123(CEMIP) 118026300(CEMIP2)
FCA101088960(TMEM2) 101092920(HYAL3) 101093011 101094000(HYAL2) 101094181(CEMIP) 101095484(HYAL4) 101095731(SPAM1)
PYU121011229(HYAL2) 121011234(HYAL3) 121013638(CEMIP2) 121028400(SPAM1) 121028401 121028402(HYAL4) 121042285
PBG122467521 122475119(CEMIP2) 122486473 122486474(HYAL4) 122487251(HYAL2) 122487254(HYAL3) 122488168(SPAM1)
PTG102952897(CEMIP) 102964157 102964452(HYAL4) 102964738(SPAM1) 102965224(HYAL1) 102966380(HYAL3) 102971665(TMEM2)
PPAD109247837 109247842(HYAL3) 109268920(HYAL4) 109268922(SPAM1) 109269038 109273553(CEMIP) 109275402(TMEM2)
AJU106965962(CEMIP) 106970630(SPAM1) 106970631 106970632 106979259(HYAL3) 106979262(HYAL2) 106985808(CEMIP2)
HHV120229234(HYAL3) 120229281(HYAL1) 120229399(HYAL2) 120236730 120236736 120236738 120238010(CEMIP2) 120248859
BTA281838(HYAL2) 353352(SPAM1) 509761 515397(HYAL1) 515491(CEMIP2) 518161(HYAL4) 519047(CEMIP) 527125 616562(HYAL3)
BOM102267588 102275599(HYAL3) 102275634 102275878(HYAL1) 102276163(HYAL2) 102278293(CEMIP) 102278479(TMEM2) 102284407(HYAL4) 102284688(SPAM1)
BIU109557586(HYAL4) 109557587(SPAM1) 109557935 109558119 109562950(TMEM2) 109575672(CEMIP) 109576069(HYAL2) 109576071(HYAL1) 109576073(HYAL3)
BBUB102389849(HYAL1) 102390497 102390506(HYAL2) 102390833 102393792(CEMIP) 102396130(CEMIP2) 102411950 102412607(HYAL4) 102415765(HYAL3)
CHX100860748(PH-20) 102168417 102168691(SPAM1) 102168908(TMEM2) 102172212(HYAL2) 102173238(HYAL1) 102175527(CEMIP) 102189274(HYAL4)
OAS101101889 101102143 101102701(CEMIP2) 101106519(HYAL4) 101107188 101116178(CEMIP) 101121207(HYAL1) 101121461(HYAL3) 443154(HYAL2)
ODA120868296(HYAL2) 120868299(HYAL1) 120868300(HYAL3) 120872125(CEMIP2) 120875530 120877304 120877537(HYAL4) 120877539
CCAD122425091 122425093(HYAL2) 122425095(HYAL1) 122437937(HYAL4) 122437938 122438594 122452839(CEMIP2) 122454886
SSC100516588(TMEM2) 100524837(HYAL4) 100738461(CEMIP) 397074(SPAM1) 404696(HYAL3) 404697(HYAL2) 404698(HYAL1)
CFR102504111(SPAM1) 102504354 102508028(CEMIP2) 102521183(CEMIP) 102521347(HYAL1) 102521929(HYAL3) 102522934
CBAI105063121(HYAL4) 105063220(SPAM1) 105063221 105067521(TMEM2) 105069122(CEMIP) 105080227(HYAL1) 105080231(HYAL3)
CDK105085347 105085422(HYAL4) 105085423(SPAM1) 105087442 105087477(HYAL3) 105094739(CEMIP) 105106250(CEMIP2)
BACU103002718(CEMIP) 103005390(HYAL3) 103006722(HYAL1) 103007213(HYAL2) 103007386(TMEM2) 103009506(HYAL4) 103009600(SPAM1)
LVE103071921(HYAL3) 103072374(HYAL1) 103073012(HYAL2) 103079092(CEMIP) 103082114(SPAM1) 103082392(HYAL4) 103083035(TMEM2)
OOR101272873(TMEM2) 101276998(HYAL3) 101277665(HYAL1) 101277905(HYAL2) 101280772(CEMIP) 101281301(SPAM1) 101281553(HYAL4)
DLE111164764(CEMIP) 111174361(HYAL2) 111174362(HYAL1) 111174363(HYAL3) 111174606(CEMIP2) 111182813(SPAM1) 111182819(HYAL4)
PCAD102981618(HYAL4) 102981903(SPAM1) 102983529(CEMIP) 102987318(CEMIP2) 102995474(HYAL2) 102996103 102996374(HYAL3)
PSIU116749211(CEMIP) 116755301(CEMIP2) 116759674(SPAM1) 116759784(HYAL4) 116762041 116762042(HYAL3)
ECB100051243(SPAM1) 100053052(CEMIP) 100055623(TMEM2) 100056514 100061845(HYAL2) 100061939(HYAL3) 106783049
EPZ103544212(SPAM1) 103546741(TMEM2) 103552969(CEMIP) 103557348(HYAL3) 103557349 103560648(HYAL4)
EAI106829838 106829839 106829872 106830729 106830730(HYAL3) 106832080 106836164(CEMIP2)
MYB102239190(HYAL1) 102249798(HYAL4) 102250717(HYAL3) 102251014(HYAL2) 102253690(TMEM2) 102257934(SPAM1)
MYD102754556(HYAL3) 102754833(HYAL2) 102770889 102770967(TMEM2) 102772512(HYAL1) 102773736(HYAL4) 102774302(SPAM1)
MMYO118665788(SPAM1) 118666450(HYAL4) 118667467(CEMIP2) 118668442(HYAL2) 118668452(HYAL3) 118668453(HYAL1) 118679105
MLF102421760(HYAL3) 102422075(HYAL2) 102423475(HYAL1) 102423485(HYAL4) 102430111(SPAM1) 102442846(TMEM2)
MNA107532324(TMEM2) 107537310(SPAM1) 107537332(HYAL4) 107541029(CEMIP) 107545075(HYAL3) 107545081(HYAL2) 107545082(HYAL1)
PKL118712176(HYAL4) 118714542(SPAM1) 118714544 118715639(HYAL2) 118715642(HYAL1) 118715643(HYAL3) 118716496(CEMIP2) 118718762
HAI109372568(SPAM1) 109372572(HYAL4) 109375181(HYAL3) 109375791(HYAL2) 109375816(HYAL1) 109381501(CEMIP) 109387007(TMEM2)
DRO112299724(SPAM1) 112299918(HYAL4) 112300227(CEMIP2) 112306143(CEMIP) 112309830(HYAL2) 112309908(HYAL1) 112309979(HYAL3)
SHON118989443(HYAL2) 118989449 118989450(HYAL3) 118991894 118993967(SPAM1) 118993968(HYAL4) 118997819(CEMIP2) 118998538
AJM119036627(HYAL1) 119036629(HYAL3) 119036683(HYAL2) 119041988 119056550(CEMIP2) 119063091 119065606(HYAL4) 119065607(SPAM1)
PDIC114488691 114491705(CEMIP2) 114501414(HYAL2) 114501418 114507228(SPAM1) 114507240(HYAL4)
PHAS123809658 123819733(CEMIP2) 123823850(HYAL4) 123829729(SPAM1) 123830501(HYAL1) 123830714(HYAL3) 123830860(HYAL2)
MMF118619686(SPAM1) 118620423(HYAL4) 118629441(CEMIP2) 118632990(HYAL3) 118633150(HYAL1) 118633201(HYAL2) 118640929
RFQ117017998(HYAL4) 117018077(SPAM1) 117018841(CEMIP) 117031927(CEMIP2) 117036739(HYAL1) 117036741(HYAL3) 117037138(HYAL2)
PALE102878728(HYAL3) 102878975(HYAL1) 102879396(HYAL2) 102891124(SPAM1) 102891363(HYAL4) 102893602(CEMIP2) 102895289(CEMIP)
PGIG120582382(HYAL2) 120582383(HYAL3) 120582385(HYAL1) 120584392(CEMIP2) 120599284 120601060(SPAM1) 120601119(HYAL4)
PVP105290167(HYAL4) 105290226(SPAM1) 105295147(HYAL2) 105295148(HYAL1) 105295149(HYAL3) 105299489(TMEM2) 105301647(CEMIP)
RAY107498913(TMEM2) 107500196(SPAM1) 107500203(HYAL4) 107500506(CEMIP) 107513380(HYAL3) 107513383(HYAL2) 107513385(HYAL1)
MJV108389072 108389922(TMEM2) 108392261(SPAM1) 108402857(HYAL2) 108402859(HYAL1) 108402860(HYAL3) 108406975(CEMIP)
TOD119232768(CEMIP2) 119245131 119246236(HYAL4) 119246248 119246254 119246260 119246272 119250465 119250494 119250503 119260527(HYAL3) 119260557(HYAL1) 119260572(HYAL2)
SARA101540035 101540295(HYAL4) 101540552 101543255(TMEM2) 101548104 101555140(HYAL2) 101555409(HYAL1) 101555418(CEMIP) 101555923(HYAL3)
LAV100661612(HYAL4) 100664537(TMEM2) 100664953(CEMIP) 100667479(SPAM1) 100669188(HYAL2) 100669471(HYAL1)
TMU101342708 101343985 101345160 101345410 101351957 101361043 101361299
DNM101416849 101417299 101420589(HYAL2) 101421259 101421333(HYAL1) 101421768(HYAL3) 101422139 101423014 101423452 101423888 101433031(CEMIP) 101441776(TMEM2)
MDO100013352(CEMIP) 100015067(TMEM2) 100016989 100017029(HYAL4) 100017190(SPAM1) 100028570(HYAL3) 100028614(HYAL1) 100028633(HYAL2) 100031013 107648899
GAS123230769(HYAL2) 123230770 123230773(HYAL3) 123236214 123247742(HYAL1) 123248568 123248624 123249465(CEMIP2) 123249514 123255725
SHR100915487(HYAL3) 100916007 100916272 100916534(HYAL2) 100918415(CEMIP) 100920054 100921314(CEMIP2) 100925107 100926676
PCW110193884(CEMIP) 110194161 110194163 110194186 110197556 110217048(HYAL3) 110217082(HYAL2) 110217129 110218833(TMEM2)
OAA100073876(CEMIP2) 100076538 100076578(SPAM1) 100077532 100078017(HYAL1) 100078126(HYAL2) 100681427(HYAL3)
GGA100859903(HYAL3) 105667218(HYAL6) 415476(CEMIP) 415478 415908(HYAL2) 417749(SPAM1) 426739(HYAL1) 427250(TMEM2)
PCOC116225370(CEMIP) 116225371 116232293(HYAL2) 116232317(HYAL1) 116238849(CEMIP2) 116241049(HYAL3) 116243730 116244297(SPAM1)
MGP100541798(SPAM1) 100541954 100542084(HYAL1) 100542238(HYAL2) 100544349(CEMIP) 100544508 104909302 104915066(CEMIP2)
CJO107306191(CEMIP2) 107308697 107308927 107318794(CEMIP) 107318795 107319561(HYAL2) 107319564(HYAL1) 107319647(HYAL3)
NMEL110389643(TMEM2) 110392510(HYAL4) 110392545(SPAM1) 110392602 110403964(CEMIP) 110403966 110404867(HYAL2) 110404888(HYAL3) 110404973(HYAL1)
APLA101790915(CEMIP2) 101795794(HYAL1) 101799098 101799286 101800183(HYAL2) 101802129(CEMIP) 101804475 106014259(SPAM1)
ACYG106042799 106043342 106043386(CEMIP) 106044477(TMEM2) 106047618(HYAL4) 106047621(SPAM1) 106047623
AFUL116493100(HYAL1) 116493101(HYAL2) 116493105(HYAL3) 116493308(CEMIP) 116493532 116498436(SPAM1) 116500564(CEMIP2) 116501953
TGU100219184 100222466(HYAL3) 100224131 100224380(CEMIP2) 100227026(HYAL4) 100228780 100229824(SPAM1) 100230220(CEMIP) 115496556
LSR110469962(HYAL1) 110469963(HYAL2) 110472582(HYAL3) 110474285(CEMIP) 110476500(CEMIP2) 110483505 110483513
SCAN103813480(SPAM1) 103813696 103816054(CEMIP) 103816969(HYAL2) 103817140(HYAL1) 103822860(CEMIP2) 103824300(HYAL3)
PMOA120507143(CEMIP2) 120509133 120510742 120510758(SPAM1) 120513985(HYAL2) 120513987(HYAL1) 120514049(HYAL3)
OTC121336367 121336371 121343663 121345384(CEMIP2) 121347107(HYAL2) 121347108(HYAL1) 121347271(HYAL3)
PRUF121348657(CEMIP2) 121351109(HYAL3) 121352862(HYAL2) 121352879(HYAL1) 121354435 121355777 121355815
GFR102032659(CEMIP) 102035392(HYAL3) 102037819(SPAM1) 102042845 102043012(HYAL4) 102044638(TMEM2) 102044902(HYAL2) 102045068(HYAL1)
FAB101807037(HYAL3) 101807147(KIAA1199) 101808121(HYAL4) 101808315 101810515(TMEM2) 101816626(SPAM1) 101820358(HYAL2) 101820552(HYAL1)
PHI102101272(HYAL1) 102102212(TMEM2) 102105429(HYAL3) 102110886(CEMIP) 102111253(SPAM1) 102112351(HYAL2) 102114472(HYAL4)
PMAJ107204172 107204979 107209471(CEMIP) 107210418 107210441(HYAL2) 107210442(HYAL1) 107216362(TMEM2)
CCAE111922967 111922968(SPAM1) 111934059(CEMIP) 111935139(HYAL3) 111935185(HYAL1) 111935321(HYAL2) 111941558(TMEM2)
CCW104683216(HYAL1) 104683435(HYAL2) 104683951 104685247(CEMIP2) 104686823(SPAM1) 104686903(HYAL4) 120410683(HYAL3)
ETL114056600(CEMIP2) 114058671(HYAL3) 114058776(HYAL1) 114058796(HYAL2) 114059030(CEMIP) 114059051 114062855(SPAM1) 114062856(HYAL4)
ZAB102061089(CEMIP) 102063403 102064181 102065026 102070233 102071824 102074664(CEMIP2)
FPG101911022(HYAL3) 101911065(CEMIP) 101911469(TMEM2) 101918475 101919114(SPAM1) 101919242(HYAL1) 101919279(HYAL4) 101919413(HYAL2) 101919451
FCH102047510(CEMIP2) 102047789 102048877 102049052 102050381(HYAL3) 102052271 102052442 102052609(SPAM1) 102055479(CEMIP)
CLV102086309 102087606 102088656(CEMIP) 102092464 102092568(HYAL1) 102092644(TMEM2) 102092745(HYAL2) 102096865 102097040
EGZ104123845(TMEM2) 104125665 104125689(SPAM1) 104126661 104126687(HYAL1) 104126688(HYAL2) 104130811 104130945(CEMIP)
NNI104008686(HYAL3) 104008712(HYAL1) 104008746(HYAL2) 104011818(SPAM1) 104011835 104017100(CEMIP) 104017244 104020879(TMEM2)
ACUN113484133(CEMIP) 113484162 113484688(HYAL3) 113484799 113484915(HYAL2) 113490097(CEMIP2) 113491205(SPAM1) 113491527
TALA104358014 104358015(HYAL4) 104358016 104363625 104363626 104363861(CEMIP2) 116959464(HYAL1) 116959470(HYAL2) 116959511(HYAL3)
PADL103915098 103915100 103920379(TMEM2) 103922717(CEMIP) 103922772 103923834(SPAM1) 103923853(HYAL4) 103923854
ACHC115333336(HYAL1) 115333400(HYAL2) 115336848(CEMIP2) 115341294 115341334 115341419(SPAM1) 115341420 115341421(HYAL4) 115353738
AAM106485952(HYAL2) 106485966(HYAL1) 106487046 106495129(HYAL3) 106495862(TMEM2) 106495897(HYAL4) 106495899 106495911 106496527(CEMIP) 106497269 106499843 106500290
AROW112960470 112963482(CEMIP) 112963542 112965234(CEMIP2) 112966626 112966627 112968847 112972976(HYAL1) 112972982(HYAL2) 112978498(HYAL3)
NPD112944403(CEMIP2) 112949994(CEMIP) 112949997 112953047(HYAL1) 112953106(HYAL2) 112953196(HYAL3) 112957912(SPAM1) 112957919
DNE112981850(CEMIP2) 112986181(HYAL1) 112986185(HYAL2) 112986936 112989444(HYAL3) 112990915(SPAM1) 112990933 112990956 112996013(CEMIP) 112996014
ASN102370740(CEMIP) 102373756 102375861(CEMIP2) 102378863(HYAL1) 102379112(HYAL2) 102383208(HYAL3) 102384522 102384773 112550426(SPAM1)
AMJ102557643(HYAL3) 102560730 102567712(CEMIP) 102574610 102574830(HYAL1) 102574839(HYAL4) 102575064(HYAL2) 102576224(TMEM2) 109284220(SPAM1)
CPOO109308772 109309095(CEMIP) 109315652 109315653 109315654(SPAM1) 109318255(HYAL3) 109318290(HYAL1) 109318293(HYAL2) 109323535(TMEM2)
GGN109288308 109288532(CEMIP) 109292033 109292034 109292035(SPAM1) 109297594(TMEM2)
PSS102444622 102449055 102450198(HYAL2) 102452468(CEMIP) 102455038(CEMIP2) 102458526(HYAL4) 102458764 102463456
CMY102931696(SPAM1) 102932459 102933270 102933500 102935818(HYAL3) 102936282(HYAL2) 102942858 102944161(HYAL1) 102944539(CEMIP2) 102946634
CPIC101935741(CEMIP2) 101937040 101938579 101939191 101939316(HYAL2) 101941627(HYAL3) 101942498 101942774(HYAL4) 101944873(HYAL1) 101946842
TST117867584(HYAL4) 117867976(SPAM1) 117868042 117878773(CEMIP2) 117880336(HYAL3) 117880389(HYAL2) 117880552(HYAL1) 117880875 117884240 117884241(CEMIP)
CABI116818136 116818139 116818140(SPAM1) 116819845(CEMIP) 116819847 116835366(CEMIP2) 116835999(HYAL1) 116836000 116836001(HYAL3) 116836008 116839678
MRV120368672(HYAL3) 120369402(HYAL1) 120371564 120372809 120372811 120374315(SPAM1) 120376911 120408096(CEMIP2) 120409287(HYAL2) 120409319
ACS100554638(cemip) 100558791 100563395(hyal3) 100563785(hyal1) 100563983(hyal2) 100567249(tmem2) 100567658(hyal4) 100567856 100568048 100568245
PVT110076667(HYAL2) 110076674(HYAL1) 110076682(HYAL3) 110077218(CEMIP) 110077283 110080634 110081701(TMEM2) 110084064 110084065
SUND121921223(HYAL1) 121921224(HYAL3) 121921295(CEMIP2) 121922667 121922935(HYAL2) 121931642 121931643 121934850 121935613
PBI103053970 103055413 103055541(CEMIP2) 103059875(HYAL3) 103060113(HYAL1) 103060345(HYAL2) 103063202 103063518(CEMIP) 103063917
PMUR107284424(CEMIP2) 107288720(HYAL2) 107288729(HYAL1) 107288731(HYAL3) 107293071 107293142 107294677(CEMIP) 107296493
TSR106542515 106545211(TMEM2) 106550543(HYAL3) 106550551(HYAL2) 106550552(HYAL1) 106552241 106554387 106555436
PGUT117661448(CEMIP2) 117667814(CEMIP) 117667820 117667842 117678385 117678984(HYAL2) 117679001(HYAL1) 117679022(HYAL3)
VKO123019842 123019894 123027715 123027716 123031675(CEMIP2) 123034163(HYAL2) 123034169(HYAL3) 123034258 123034331(HYAL1)
PMUA114583937 114583938(CEMIP) 114588622 114591530(HYAL3) 114591533(HYAL1) 114591534(HYAL2) 114591580 114605520 114605521 114606223(CEMIP2)
ZVI118076721(CEMIP2) 118080137 118080583(HYAL3) 118080587(HYAL1) 118080588(HYAL2) 118080620 118091107 118091109 118093031 118093186(CEMIP)
GJA107105438(CEMIP) 107106781(TMEM2) 107108394 107108395 107116007(HYAL1) 107116008(HYAL2) 107118546 107118632(HYAL3)
XLA100337508(hyal2.L) 108706972(cemip2.S) 108711150(hyal4.L) 108711451 108711452(cemip.L) 108712855(cemip.S) 108714490(cemip2.L) 108714598(hyal1.L) 380470(hyal2.S) 398285(spam1.L)
XTR100037890(hyal4) 100144942(hyal2) 100379691(cemip2) 100486024(spam1) 100491930 100492102(cemip) 100498156(hyal1)
NPR108788019 108791715(TMEM2) 108799899(CEMIP) 108799971 108800585 108800589 108800591 108800592
RTEM120931208 120931210 120931837 120943284(CEMIP2) 120944794 120944795 120944967 120944968 120944969 120944970
BBUF120979665(HYAL2) 120979669 120981997(HYAL4) 120985762 120985923 120989160(CEMIP2)
BGAR122922329(CEMIP2) 122922523 122922529 122922534 122925578 122925820 122927570 122927572
DRE100003660(cemip) 100004557(hyal3) 108181664 559228(hyal2b) 562480(si:dkey-72l14.3) 566851(cemip2) 567869(hyal2a) 664772(hyal1) 791189(hyal6) 791203(spam1)
SRX107709485 107711933 107711968 107717507 107717524 107724516 107736981 107744379 107744380 107744425(tmem2) 107752304 107752305 107753633 107753713 107756016
SANH107659472 107659484 107662322 107666174 107669627 107669647 107672701 107673411(tmem2) 107679458 107679511 107691638 107695624 107696394 107696458 107698280 107698319 107704436
SGH107553744 107556477 107556495 107573489 107573512 107586928 107587575(hyal2) 107587576 107591290 107591777 107591782 107592377 107593055 107595438 107598834 107598911 107599911
CCAR109046499 109052901 109054564(cemip) 109057398 109057399 109063193 109068093 109074046 109074047 109075060 109080507 109082467 109083648 109095570 109110146
CAUA113040233 113043436 113043437 113049892 113050165 113050167 113051998 113052010 113064736 113066979 113066980 113078402 113079540 113091304 113093962 113093966 113094804 113104044 113105678 113106732 113107975
IPU108254948(hyal2b) 108255674(cemip2) 108265127(si:dkey-72l14.3) 108265970 108270987 108271980(hyal1) 108271981(hyal2a) 108274420 108274445 108274446 108274447
PHYP113526942 113530008 113530148 113530220 113534670 113536418(cemip) 113539499 113539526 113542350(cemip2)
SMEO124375255(hyal2a) 124380554(cemip2) 124391272 124391300(hyal1) 124392619 124392928 124392929 124399529(si:dkey-72l14.3) 124400362(hyal3) 124402448(hyal2b)
AMEX103023449(tmem2) 103025118(cemip) 103027345 103027908 103028224 103028309 103032073 103034129 103034453 103035727 103039131 103041502
EEE113568061 113571567 113571631 113573933(cemip) 113575841 113575871 113582166 113582602 113583177 113583514(cemip2) 113583824
TRU101068133 101069958 101071886 101072113 101072276 101072329 101072523(cemip2) 101074427 101074654
TNGGSTEN00003306G001 GSTEN00008974G001 GSTEN00019698G001 GSTEN00020430G001 GSTEN00022608G001 GSTEN00027406G001 GSTEN00027520G001 GSTEN00027522G001
LCO104918358 104925136 104927980 104927981 104927992 104927993 104928018 104930947 104930948(hyal2) 104931138(cemip2) 104932594 104936188(cemip)
NCC104941323 104951555(hyal2) 104951556(hyal1) 104952267 104955607 104955909(spam1) 104962279 104962280 104962283 104966814 104967232(tmem2) 104967514
CGOB115005269 115005270 115005271 115008215 115008291 115008750(hyal2) 115009222 115010424 115010468 115013711(cemip2) 115025498(cemip) 115028491
ELY117249512 117252657(cemip2) 117254226 117256184(hyal2b) 117256514(hyal1) 117257535(hyal2a) 117257652(hyal3) 117258506(si:dkey-72l14.3) 117262216 117262217 117262218(hyal6) 117262220
PLEP121938119 121941822 121944289(cemip2) 121947267(hyal3) 121947572(si:dkey-72l14.3) 121949693 121949695(hyal6) 121949696 121950021(hyal1) 121958158(hyal2a) 121958649(hyal2b) 121961602
SLUC116036273 116036275(hyal6) 116036281 116036282 116040834(si:dkey-72l14.3) 116041583(hyal2b) 116050761 116051546(hyal2a) 116051573(hyal1) 116054419(cemip2) 116060200
ECRA117938381 117942242(cemip) 117942979(hyal2a) 117942981(hyal1) 117943903(hyal2b) 117944443(cemip2) 117947740(si:dkey-72l14.3) 117949729 117949730(hyal6) 117949735 117949736
PFLV114550178 114554061(hyal2) 114554135 114554329 114554336(cemip) 114555475(cemip2) 114558556 114559132 114560108 114560347 114560348 114560349
GAT120808725(hyal6) 120809717(spam1) 120809729 120829318(si:dkey-72l14.3) 120830639(cemip2) 120834688(hyal1) 120834689(hyal2a) 120835603 120835813(hyal2b)
PPUG119194093(hyal2b) 119194133(hyal1) 119194269(hyal2a) 119195232 119195475 119195476(hyal6) 119195477(spam1) 119199516(si:dkey-72l14.3) 119204549 119222161(hyal3) 119225229(cemip2)
MSAM119882333 119886008(hyal2b) 119886251(hyal2a) 119886252(hyal1) 119891453(cemip2) 119893097 119893176(hyal6) 119894110 119894190 119905714(hyal3) 119905727(si:dkey-72l14.3) 119917927
CUD121505799 121506821(abhd14a) 121507060(hyal2a) 121507236(hyal1) 121509484(cemip2) 121511380 121513444 121514550 121514809 121515413 121515684(hyal6) 121517137(hyal3) 121517852(si:dkey-72l14.3)
MZE101466457 101470336 101470393 101471008 101476387(cemip2) 101478695 101478980 101479457 101481804(cemip) 101482011(hyal2) 101482688
ONL100694051 100699578 100702304 100702641 100702909 100703179 100703350(hyal2) 100706739 100708192(cemip2) 100709157 102083001(cemip)
OAU116309822 116313670(hyal2b) 116313915(cemip2) 116319262(hyal6) 116319280 116323724 116324686(si:dkey-72l14.3) 116324701(hyal3) 116334260(hyal1) 116334277(hyal2a) 120440909
OLA101155189 101155920 101159583 101161047 101168117 101169103 101170178 101170425 101171340(tmem2)
OML112139093 112141244(spam1) 112141252(hyal6) 112141264 112144497(hyal1) 112145762(hyal2a) 112145774(hyal2b) 112148228(cemip2) 112152371 112159355(si:dkey-72l14.3) 112159636(hyal3)
XMA102216371 102216625 102218221 102218482 102218730 102219922(tmem2) 102223880(hyal2) 102236740 102237035 102238176 102238295 111605808 111605863 111605865 111608427(cemip)
XCO114135144(hyal1) 114135145 114135147 114135148 114135149 114135150(hyal2) 114135788 114135789 114135790 114135882 114142534 114143434(cemip) 114143524 114143797 114149323 114154338 114154604(cemip2)
XHE116709663 116709760 116709844 116710199 116710392 116710619 116710874 116710875 116711119 116719138(cemip) 116721592 116729860(cemip2)
PRET103460418 103460420 103460859 103460860 103462352(cemip) 103464510(hyal2) 103464511(hyal1) 103464614 103464615 103464627 103465097 103465101 103465990 103467131 103470492(tmem2) 103473528
PFOR103129534(cemip) 103136956 103136965 103137977 103138453 103138462 103145599(tmem2) 103152701 103152702 103152703 103154001 103155921
PLAI106937593 106939972 106940902 106941028 106941030 106941031 106942377 106956350 106957320 106957322 106962474 106965109
PMEI106908696 106909868 106911070 106911778 106912450 106912452 106912648 106922577 106925035 106925042 106925225 106925226 106925243
GAF122821204 122827962(cemip2) 122830251(si:dkey-72l14.3) 122831723(hyal3) 122833793(hyal1) 122834194 122834509 122834513 122836089(spam1) 122836090 122836091(hyal6)
CVG107089317(hyal2) 107089319 107092178 107092189 107092191 107092193 107094269(cemip) 107098940 107100449(tmem2) 107102915 107102937
CTUL119775067(hyal1) 119775110(hyal2a) 119777771(hyal6) 119777772 119777773 119777774 119779982(hyal2b) 119783951(cemip2) 119789079(si:dkey-72l14.3) 119789236(hyal3) 119798269
NFU107385134 107385227 107385228(hyal2) 107389501 107389502 107389503 107390589 107390663 107393779(tmem2)
KMR108231210(hyal2a) 108231224(hyal1) 108233042(hyal3) 108233059(si:dkey-72l14.3) 108236586(cemip2) 108247372(hyal2b) 108247453(hyal6) 108247456 108247457 108247463 108251361
ALIM106513082 106516068 106516188 106516190(hyal2) 106517222 106517223 106517224 106531528(cemip) 106531729 106534816(tmem2)
NWH119412378(hyal2a) 119412470(hyal2b) 119412768(hyal1) 119413459(cemip2) 119415862 119415864(hyal6) 119415867(spam1) 119417696(si:dkey-72l14.3) 119417703(hyal3) 119425800
AOCE111563235 111564509(cemip) 111578654(tmem2) 111579912 111579915 111580846 111581541 111581544 111581546 111581547
CSEM103378950(cemip) 103379869 103379870 103379871 103379872 103382834 103385031 103385649(hyal1) 103385650 103385817 103398221(tmem2)
POV109623971 109624113 109624262 109624268 109624862(cemip) 109630574 109630576 109633754(tmem2) 109638450 109638622(hyal2) 109638635 109642784
SSEN122757973 122767243 122768687(hyal2b) 122768762(hyal1) 122768854(hyal2a) 122770048(cemip2) 122772414 122776000 122776001 122776002 122776522(hyal6) 122776631(hyal3) 122777404(si:dkey-72l14.3)
HHIP117757514 117759497(cemip) 117761138(hyal2b) 117761537(hyal2a) 117761538(hyal1) 117763086(hyal6) 117763491 117763637 117763722 117764188(hyal3) 117764707(si:dkey-72l14.3) 117767960(cemip2)
LCF108878515(tmem2) 108882543 108882561 108889385 108894243(cemip) 108899253 108899272(hyal2) 108903034 108903041 108903052 108903064
SDU111220298(cemip) 111222871(hyal2) 111222903 111222919 111224583 111229690(tmem2) 111230722 111230732 111235955 111235956 111235987 111236009
SLAL111644379(cemip) 111653811(hyal2) 111653815 111660861 111663663 111663920(tmem2) 111665054 111665072 111665073 111665097 111665105 111666378
XGL120783132(hyal2b) 120783278(hyal2a) 120783445(hyal1) 120788575 120793315 120793452 120793457(hyal6) 120793461 120803875 120804171(hyal3) 120804522(si:dkey-72l14.3) 120805437(cemip2)
HCQ109509966(cemip) 109510647(hyal1) 109510664(hyal2) 109511826 109522643 109522975 109522977 109522979 109525225(tmem2)
BPEC110154426 110154427 110162588(cemip) 110164398 110166766 110166862 110168587 110168617 110168636(hyal1) 110168818 110168822 110169925(tmem2)
MALB109952394 109956352 109956353 109956407 109956408 109956940(tmem2) 109959024 109959026 109970940(cemip) 109973767
SASA106561028 106561029 106561030 106562656(cemip) 106565174 106565981(HYAL2) 106565982 106566776(HYAL2) 106572263 106576126 106580058 106582795 106583436(HYAL2) 106584561 106584562 106585357 106585712
OTW112214719 112215851(si:dkey-72l14.3) 112217167 112218217 112218218 112218219 112219983 112220044 112222110(hyal3) 112240112 112247319(hyal1) 112247320 112248196(cemip2) 112254293 112254922 112263238
OMY110490745 110492323(hyal3) 110492772 110492782 110492793 110494019 110494654 110494655(hyal1) 110521336 110521337 110525412 110526709 110527809 110528441 110532089(si:dkey-72l14.3) 110535043(cemip2) 118964944
OGO123995503 124003069(hyal1) 124003117 124003394 124010034 124010113 124010185 124019835 124027884 124031551 124031773(si:dkey-72l14.3) 124034510(cemip2) 124036091 124037024 124037592 124045745(hyal3)
ONE115102173 115106106 115111378 115117171 115131978 115133825 115134473 115134795 115134796 115136441 115139817 115142732 115143155 115143443 115143445 115145439
SALP111951336 111958112 111960955 111961147 111962171 111966282 111969788 111970060 111970072 111970414 111971650 111972336 111974272 111977004 112070371(hyal2)
SNH120020396 120024768 120031808 120042820 120051765 120051771 120053123 120058724(si:dkey-72l14.3) 120058998 120061276(hyal3) 120063102(cemip2) 120063780 120065372 120065624 120066579 120066581 120066582
ELS105006088 105009887 105009888 105014491(cemip2) 105014578(cemip) 105018611 105020148 105025254 105025267 105025417 105025418 105028115 109614542
SFM108918700 108918701 108925563 108925573 108931432 108931489 108931498 108933814 108933821 108938996(cemip2) 108940242 108941226 108941976
PKI111833636 111833638 111833639 111833641 111833642 111839401(tmem2) 111844923(cemip) 111848762 111848772 111851421 111855843 111857541 111857833 111859912 111860023 111860027
AANG118206610(cemip2) 118207978(si:dkey-72l14.3) 118208324(hyal2a) 118208389(hyal3) 118208668(hyal1) 118211859(hyal2b) 118215386 118215387 118228511(cemip) 118231418 118231471(hyal6) 118231864 118232068 118232069(spam1)
LOC102685934 102687134(cemip) 102687941(tmem2) 102693429 102693624 102693823 102694022 102694223 102694927 102696253(hyal1) 102696446(hyal2) 102698412
PSPA121294547 121294742 121297729 121297882 121298022 121298084 121298371 121298373 121299288 121299289 121319029 121319030 121319031 121319120(hyal6) 121319140(cemip2) 121319783 121328259 121328443 121329146
ARUT117404289 117411786 117411884 117411905 117412137 117412638 117414599 117415392 117420082 117420084 117420085 117421131(cemip2) 117427752 117429034 117963474 117964010 117964042 117964063 117964102 117967703 117969339 117971350
LCM102345611(HYAL2) 102349128 102350113(TMEM2) 102354923(HYAL4) 102355176 102355191(SPAM1) 102356817 102358134 102358666 102361347 102367458(CEMIP)
CMK103176598 103176705 103176804 103181838(hyal6) 103181890 103182555 103187195(cemip2) 103187599 103187600
RTP109914265(tmem2) 109924060 109925459 109927766(spam1) 109927770(hyal4) 109928274 109934026 109935962 109935966 109936338 109936348(cemip)
BFO118404407 118404521 118405012 118411529 118411751 118415409 118415410 118415413 118416617 118416838 118416840 118416841 118421464 118427732 118429376 118429839 118430088 118430089 118430687
BBEL109469310 109472035 109472041 109472051 109472407 109472527 109472528 109472857 109472972 109474158 109475028 109479776 109479777 109481579 109483020 109483027
CIN100186831
SCLV120341020 120344917 120347898
SPU115924575 575967 582946 584769
APLC110973932 110990066
SKO100377225
AGAAgaP_AGAP011479
ACOZ120958015
AARA120902874
AAG5578235
AALB109401309 109623273
CQUCpipJ_CPIJ018328 CpipJ_CPIJ018329
CPII120416432 120416735 120424997
CNS116340278
AME406146
ACER107998690
BIM100743050
BBIF117214033
BVK117242244
BVAN117155064
BTER100651053
BPYO122574566
CCAL108623515
OBB114874207
MGEN117226235
NMEA116427063
CGIG122402040
SOC105196779
MPHA105831859
AEC105148714
ACEP105623333
PBAR105426307
HST105188713
DQU106745903
CFO105251112
FEX115246141
LHU105669752
PGC109856266
OBO105284697
PCF106786428
PFUC122526363
VPS122633265 122633274
NVI100115714
CSOL105365060
MDL106694078
CGLO123259550 123269300
FAS105265723
DAM107039604
AGIF122848107
CCIN107267958
TCA661685
DPA109537076
SOY115881634
ATD109602967 109603241
CSET123320374
AGB108916042
LDC111505889
NVL108567699
APLN108739604
PPYR116162072 116177401 116177402
OTU111424977
BMOR101735594
BMAN114246843
MSEX115444614
DPLKGM_206423 KGM_206424
BANY112054776
PMAC106714963 106716017
PXU106118667
PRAP111001369
ZCE119836628
HAW110371171
TNL113499184
OFU114358255
API100166159
DNX107173173
AGS114123047
RMD113549824
BTAB109042515
CLEC106665115 106674337
HHAL106692488
NLU111048499 111055521
PHUPhum_PHUM286990 Phum_PHUM287000 Phum_PHUM287010 Phum_PHUM287020
FOC113205517
PVM113823457
PJA122251479
PCLA123775274
PTRU123501587
HAZT108669953
CSCU111627617 111642077
PTEP107451035
CELCELE_T22C8.2(chhy-1)
CBRCBG_00535(Cbr-chhy-1)
LOALOAG_10485 LOAG_11260 LOAG_14903
NAINECAME_13092 NECAME_13094 NECAME_13095 NECAME_13181 NECAME_14184 NECAME_17286 NECAME_17635
LGILOTGIDRAFT_160629 LOTGIDRAFT_168965 LOTGIDRAFT_228278 LOTGIDRAFT_228687 LOTGIDRAFT_83086 LOTGIDRAFT_95501
PCAN112558734 112560791 112560853 112566660 112566661
BGT106057545
GAE121381579 121381714 121390123 121390151 121390211 121390499
HRF124115551 124115554 124115560 124118125 124118126 124123820 124129470 124142805 124143614 124145785 124145786 124145802 124148801
HRJ124256273 124256289 124271588 124274900 124277760 124284484 124286887 124289105 124289111 124289118 124289128
CRG105327389 105332347 105334184 105339776 105339777 105346616 105346625 117684304
MYI110449085 110450217 110456151 110456153 110456159 110456168 110456172 110458969 110465680
PMAX117319062 117319078 117321708 117321884 117322076 117322077 117340260 117340889 117341913 117345040
MMER123526145 123526146 123526810 123530841 123530866 123530868 123535691 123552380
OBI106869911 106869912
OSN115218003 115218079
LAK106162640 106163632 106167982 106169034 106170529 106171125 106171617 106174112 106174697 106175340 106179390 106180576 106181361
NVE5520004 5520016 5520081
EPA110241411 110251597
ATEN116287214 116299091 116305249
ADF107340094 107346484
AMIL114959196 114975971
PDAM113672213 113672824
SPIS111318943 111326369 111329380
DGT114518013
XEN124444472
HMG100204026
MNGMNEG_10692
DDIDDB_G0270636 DDB_G0287365
DPPDICPUDRAFT_98088 DICPUDRAFT_98926
DFADFA_02674 DFA_08805
FCYFRACYDRAFT_261519
EHXEMIHUDRAFT_212281
NGRNAEGRDRAFT_46424 NAEGRDRAFT_46431 NAEGRDRAFT_53564 NAEGRDRAFT_56847 NAEGRDRAFT_66275 NAEGRDRAFT_66848 NAEGRDRAFT_69038 NAEGRDRAFT_69629 NAEGRDRAFT_71289 NAEGRDRAFT_72273 NAEGRDRAFT_75989
XCCXCC2028
XCBXC_2155
XCAxcc-b100_2329
XCPXCR_2312
XCVXCV4043
XAXXACM_3822
XACXAC3928
XCIXCAW_00349
XCTJ151_04107
XCJJ158_04083
XCUJ159_04079
XCNJ169_04104
XCWJ162_04084
XCRJ163_04079
XCMJ164_04080
XCFJ172_04097
XFUXFF4834R_chr38180
XAOXAC29_19935
XOMXOO0189(XOO0189)
XOOXOO0215(Chb)
XOPPXO_03654
XOYAZ54_01035
XORXOC_4258
XOZBE73_02210
XSASB85_10895
XFRBER92_01595
XVEBJD12_10500
XPEBJD13_19310
XHRXJ27_13665
XGABI317_02885
XPHXppCFBP6546_14760(XppCFBP6546P_14760)
XVAC7V42_20215
XANAC801_19605
XARXB05_14600
XCZEBN15_18440
XEUXSP_003729
XHDLMG31886_40640
MAQMaqu_3474
MHCMARHY3369
MADHP15_3245
MBSMRBBS_3509
MSRAU15_02470
MSXAU14_08640
MPQABA45_16460
MARIACP86_06760
MLQASQ50_08380
MSQBKP64_17465
MARAD0851_10255
MARJMARI_31840
CJACJA_1347(hyl84)
CEBB0D95_01855
CELLCBR65_07415
CEKD0B88_09995
CEGD0C16_09015
SPOIIMCC21906_02147
ZALAZF00_09475
OSGBST96_16375
KIMG3T16_20530
AFUSEYZ66_06715
METUGNH96_06780
NAXHC341_03570
GAIIMCC3135_00340(nagJ)
HAHEENC22_15520
AHAAHA_1474
AHYAHML_08195
AHDAI20_11820
AHRV428_08425
AHPV429_08430
AHJV469_15065
AHHRY45_08040
AHIVU14_15225
AAJBOQ57_07120
ASAASA_2891
AEOO23A_p2099
AVRB565_2712
AVOAMS64_16320
AMEDB224_3724
ASRWL1483_3168
ADHCK627_18730
AEMCK911_10170
AEAC2U39_06920
ARVC7N77_18495
AESC2U30_06665
AELNCTC12917_01334(nagJ)
ASIMFE240_05340
AALLI6G90_01475
AJDI6H43_03605
ARIVKYK33_07225
CRZD1345_06855
CHAECH06BL_14830
MSDMYSTI_01855
MFBMFUL124B02_31295
AGEAA314_03421
RFERF_p56 RF_pd56
PLAPlav_1649
NWINwi_0717
NHANham_0836
MSLMsil_1758
PHBHYN04_08800
AEXAstex_2731
RLIRLO149_c032190
HBCAEM38_12230
NOVTQ38_025165
NORFA702_18370 FA702_21275
STAXMC45_11905
SPHITS85_03725
SNJA7E77_14930
SMYBJP26_08285
SPLKAV944_14970
SPAUDRN02_008525
SLANGV829_11790
SMICSmB9_36690
SPHSETR14_05195
AAYWYH_03091 WYH_03304 WYH_03310
APBSAR116_2153
BDAFSZ17_06215
ASEDIRT44_11360
VHLBME96_14800 BME96_15585 BME96_15590
VILCFK37_08530 CFK37_09225 CFK37_10320
VNECFK40_05195
GRCGI584_06195
NMKCHR53_25300 CHR53_25470 CHR53_25475 CHR53_25480 CHR53_27835
BVJI5776_03875
BBEBBR47_17990
BLRBRLA_c012190
BFMBP422_04170
BAGRBA6348_19975
BRWGOP56_21965
BCHSJNE38_09690
BCOPJD108_15665
PPYPPE_00341
PPMPPSC2_01915(hyl)
PPOPPM_0365(hyl)
PPOLX809_01520
PPQPPSQR21_003430
PPOYRE92_10015
PTAHPL003_09490
PLVERIC2_c20510(nagJ)
PAENP40081_31050
PAEFR50345_09880
PAEQR50912_27795
PAEAR70723_26645
PAEJH70737_09440
PPEOABE82_01765
PDHB9T62_02240
PKBB4V02_23295
PAIHASL14_10115
PALBEJC50_28950
PCHIPC41400_08420
PBKBack11_32710
PTRIKDC22_16560
AFXJZ786_13380
TUMCBW65_12910 CBW65_19250
TABCIG75_10185
NTRB0W44_11820
SPYSPy_0701(hylP1) SPy_1600
SPZM5005_Spy1314(hyl)
SPYMM1GAS476_1381(hyl)
SPYAA20_1348c(hyl)
SPMspyM18_0770(hylP) spyM18_1606(hyl)
SPGSpyM3_0929(hylP.2) SpyM3_1214(hylP.4) SpyM3_1294(hyl)
SPSSPs0567 SPs0648
SPHMGAS10270_Spy0590 MGAS10270_Spy1310 MGAS10270_Spy1430(hyl)
SPIMGAS10750_Spy0615 MGAS10750_Spy1423(hyl)
SPJMGAS2096_Spy1334(hyl)
SPKMGAS9429_Spy0586 MGAS9429_Spy1308(hyl)
SPFSpyM50524 SpyM50541 SpyM50680 SpyM51271
SPAM6_Spy1332 M6_Spy1550
SPBM28_Spy1355(hyl)
STGMGAS15252_1199
STXMGAS1882_1115 MGAS1882_1260
SOZSpy49_1236c(hyl)
STZSPYALAB49_000995 SPYALAB49_001292 SPYALAB49_001308
SPYHL897_04975 L897_06535 L897_07515
SPYOSTAB901_06555
SEZSez_1507(hylZ)
SEQSZO_04490
SEZOSeseC_02032(hya)
SEQUQ426_01285
SEUSEQ_1693
SDSSDEG_1588(hyl)
SDGSDE12394_08290
SDAGGS_1455(hyl)
SDCSDSE_1739(hyl)
SDQSDSE167_1709(hyl)
STKSTP_1213 STP_1214
SCAINCTC12191_01152(hyl)
LCTBI355_1875
LALILA20249_05340
EFUHMPREF0351_12988(hyl)
TKRC7K43_02085
VAOFA707_04120
VHYG7082_10700
CMLBN424_3030(hyl)
CARCNY10_1498
GADK8O88_03375
CPECPE0191 CPE0881 CPE1234 CPE1279 CPE1523
CPFCPF_0184(nagH) CPF_0875 CPF_1442(nagJ) CPF_1487
CPRCPR_1248
CBVU729_414
CCHVBTM20_02905 BTM20_03575
CSEPCP523_03555 CP523_04220 CP523_04915 CP523_04930 CP523_04950 CP523_05130
FSAC5Q98_04560 C5Q98_07220
DEDDHBDCA_p2011
DECDCF50_p2023
DRSDEHRE_01505
AACXDEACI_2673
STHRBXT84_12015
TTOThethe_01898
TSHTsac_2289
APRApre_0148
SSGSelsp_1425
SRISELR_08510
AARGAargi30884_26520
ABSIA9CBEGH2_23850
ERMEYR00_03915 EYR00_03935
FITFi14EGH31_20890
AMUOKWG62_04250 KWG62_07980 KWG62_08985 KWG62_09020 KWG62_09035
ALLOKWG61_00370 KWG61_04280 KWG61_14430
LPILLIP_0414 LIP_2435
MNUNCTC10166_00357(nagH)
MCYMCYN_0715(MCYN0715)
CCYCSCMU_00620
SALBXNR_2089 XNR_4292
SGRSGR_4877
SGBWQO_11075
SSXSACTE_2080
SVLStrvi_5205 Strvi_7941
SRCM271_31960 M271_46640
SMALSMALA_0277 SMALA_2653
SSOII1A49_04845 I1A49_17200
SFASfla_1448 Sfla_4228
SBHSBI_00159 SBI_07080
SVESVEN_2438
SALSSLNWT_7238
STRPF750_2484 F750_5429
SFISFUL_2231
SALUDC74_3168 DC74_6418 DC74_7083
SALLSAZ_16910 SAZ_32240 SAZ_36730
SGUSGLAU_12155
STREGZL_01022 GZL_02592 GZL_05761
SCWTU94_11620
SLDT261_1828 T261_5410
SLCSL103_05840 SL103_25090
STRMM444_12985
STRCAA958_09820 AA958_28465
SAMBSAM23877_1062 SAM23877_2700
SPRISPRI_1498 SPRI_4862
SCZABE83_24825
STRFASR50_12850
SLEsle_45640(sle_45640)
SRNA4G23_01727(nagJ)
STSIA4E84_13980
SKYD0C37_12165 D0C37_23100
SALWCP975_12090
SLSSLINC_6481
SNRSNOUR_11055 SNOUR_27095
STRDNI25_36120
SNWBBN63_23315
SAUOBV401_05140 BV401_16825
SSIAA7J05_23755
SVUB1H20_10320
SGVB1H19_15215
SLAUSLA_2333
SALJSMD11_4482(hya)
SLXSLAV_24290
STROSTRMOE7_14050
SFKKY5_2790
SGEDWG14_02048
SLKSLUN_13525
SDXC4B68_26435
SQZFQU76_09705
SASTCD934_22015
STIRDDW44_08545
SKACP970_28635
SGZC0216_25845
SNKCP967_22975
SHAWCEB94_14405
SRKFGW37_11200
SFICEIZ62_01020 EIZ62_21950
SSPODDQ41_06880
SVRCP971_09685
SPADDVK44_09345
SAQUEJC51_36230
SCAVCVT27_09855
SBYH7H31_24235
SRIMCP984_07670 CP984_26765
SPHVF9278_05285
SCINCP977_11885
SFUGCNQ36_12095
SPACB1H29_24135
STSUB7R87_09575
SGXH4W23_14340 H4W23_25465
SCOECP976_15550
SBATG4Z16_23225
SSPBCP982_16105
SNFJYK04_03287
SPLACP981_13575 CP981_30820
STUIGCM10017668_23310
SATAC5746_14385 C5746_37420 C5746_39255
SCHFIPT68_25885
SFEUIM697_32850
SLIAHA039_23210
SDWK7C20_12865 K7C20_29440
SVDCP969_14450
SCALI6J39_10535
SAUHSU9_011105 SU9_028305 SU9_033500
SFBCP974_09690
SMOBJ7W19_10855
SPRACP972_12710
SPEUCGZ69_12140
SROIIAG44_04630 IAG44_37670
SXNIAG42_07570 IAG42_23355
SGJIAG43_10550
SHKJ2N69_12240
SANUK7396_07750 K7396_23775
KSKKSE_54890
KABB7C62_10000
KAUB6264_04765
KITCFP65_5355
SALAESZ53_09340
ARZAUT26_00055
ARNCGK93_00065
ARXARZXY2_3886(hya)
ARIUM93_02995
PUEFV140_00055
BRXBH708_12545
BGGCFK41_00605
BRZCFK38_12075
LMOIVV02_00325
PSEIGCE65_01905 GCE65_11130
PADTIIST44_11080
CACNRN83_03935
PRLBCB70_12070
KFLKfla_3229
NOABKM31_02665
NOWGBF35_35380
NGNLCN96_39640
SENSACE_0529 SACE_7066
SACGFDZ84_14415
AOIAORI_3373(hya)
AJAAJAP_22360
AMYCCU254_16490
AMYBBKN51_15860
AABA4R43_06845
AMYYYIM_20355(nagJ)
AORISD37_17520
KALKALB_2454
KPHYAOZ06_30485
AHMTL08_13385
ACTIUA75_14920
ACADUA74_14330
AHGAHOG_13470(nagJ)
SACEGIY23_02240
MSAGGCM10017556_02140 GCM10017556_51520
ATLAthai_25220
ASERAsera_49480
SNASnas_2451
AHWNCTC11636_02503(nagJ)
ASLANCTC11923_01310(nagJ)
AVUBK816_06985
BBPBBPR_1635
BBIBBIF_1576
BBFBBB_1610(nagH)
AEYCDG81_02400
CSTCLK434_07695 LK434_09760
AMRAM1_0334
TTRTter_0116
DMRDeima_1170
DPDDeipe_0032
DABAUC44_02525
DFCDFI_11520
DEINDAAJ005_15900
DGADEGR_04500
MRBMrub_1368
MREK649_06500
MSVMesil_2085
MTAIMtai_v1c16060
AMUAmuc_0052
AGLPYTT_0357
SOAG3M56_003480 G3M56_006375
PNDPla175_43340
PBASSMSP2_00909
BTHBT_4395
BTHOBtheta7330_03705
BFRBF4022
BFSBF9343_3695
BFGBF638R_3871
BFBVU15_18105
BHLBache_1389 Bache_2906
BCACCGC64_08300
BZGC4H11_00430
BHFC3V43_05505
BUNBun01g_36950
BFEK6V30_10500
BNOK8P02_01275
BVUBVU_2069
BDOEL88_03340
BDHGV66_10670
PCOPI6J50_11170
PDIBDI_1142
PARCCI960_09425
PMERINE87_00254
PGOLK6V26_08530
PJOLK449_05790
PARYA4V02_09055
BVSBARVI_02830 BARVI_04265 BARVI_06650
COPRCop2CBH44_04530 Cop2CBH44_31060
BUYD8S85_06900
BVIRI6J59_10070
PMZHMPREF0659_A5046
PDNHMPREF9137_0590
PFUSADJ77_06260
PJECRM71_08685
POCNCTC13071_00507
PMUFJ4864_05120
PHISJ5A62_08160
ALQC7Y71_001750 C7Y71_009265
ADAA5CPEGH6_03110
RBCBN938_1905
CPICpin_5708
CHIHGWR21_12780
ARKD6B99_13940
AGIFSB73_06185
PEPAQ505_01415
SHTKO02_20065
MRUBDEO27_011605
CCMCcan_17870
CCYNCGC48_11185
CAPHCGC49_00045
CSTOCGC58_12095
CAPQCGC52_00045
ZPRZPR_3254
AQAD1815_18560
ORHOrnrh_0573
ORIQ785_06875
ELTFGE20_09735
OCYOSSY52_04120 OSSY52_18200
PMOPmob_0472
DTNDTL3_1494
KPFIX53_06900
MPGTheba_0994
MINFMESINF_2633
SMRSmar_0708
SHCShell_0085
 » show all
Reference
1
  Authors
Meyer, K., Hoffman, P. and Linker, A.
  Title
Hyaluronidases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 4, Academic Press, New York, 1960, p. 447-460.
Reference
2
  Authors
Rapport, M.M., Myer, K. and Linker, A.
  Title
Analysis of the products formed on hydrolysis of hyaluronic acid by testicular hyaluronidase.
  Journal
J Am Chem Soc 73:2416-2420 (1951)
Reference
3  [PMID:13271353]
  Authors
WEISSMANN B.
  Title
The transglycosylative action of testicular hyaluronidase.
  Journal
J Biol Chem 216:783-94 (1955)
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.35
IUBMB Enzyme Nomenclature: 3.2.1.35
ExPASy - ENZYME nomenclature database: 3.2.1.35
BRENDA, the Enzyme Database: 3.2.1.35
CAS: 37326-33-3
LinkDB

KEGG   REACTION: R07824
Entry
R07824                      Reaction                               
Definition
G13043 + H2O <=> DWA-2 + N-Acetylgalactosamine
Equation
Enzyme
Pathway
rn00531  Glycosaminoglycan degradation
rn01100  Metabolic pathways
Module
M00076  Dermatan sulfate degradation
M00077  Chondroitin sulfate degradation
Orthology
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
LinkDB

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