KEGG   ORTHOLOGY: K01388
Entry
K01388                      KO                                     
Symbol
MMP1
Name
matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
Pathway
map03320  PPAR signaling pathway
map04657  IL-17 signaling pathway
map04926  Relaxin signaling pathway
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05219  Bladder cancer
map05323  Rheumatoid arthritis
map05417  Lipid and atherosclerosis
Disease
H00028  Choriocarcinoma
H01714  Chronic obstructive pulmonary disease (COPD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09152 Endocrine system
   03320 PPAR signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
   04926 Relaxin signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09162 Cancer: specific types
   05219 Bladder cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09163 Immune disease
   05323 Rheumatoid arthritis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.7  interstitial collagenase
     K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M10
   K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Genes
HSA: 4312(MMP1)
PTR: 451510(MMP1)
PPS: 100995251(MMP1)
GGO: 101131051(MMP1)
PON: 100459931(MMP1)
NLE: 100582292(MMP1)
MCC: 703653(MMP1)
MCF: 102142258(MMP1)
MTHB: 126936364
CSAB: 103248335(MMP1)
CATY: 105588779(MMP1)
PANU: 101000222(MMP1)
TGE: 112607316(MMP1)
RRO: 104674665(MMP1)
RBB: 108514074(MMP1)
TFN: 117081260(MMP1)
PTEH: 111540071(MMP1)
CJC: 100400727(MMP1)
SBQ: 101051246(MMP1)
CSYR: 103277141(MMP1)
LCAT: 123641886(MMP1) 123641888
OGA: 100951906(MMP1)
MMU: 83995(Mmp1a) 83996(Mmp1b)
MPAH: 110327208
RNO: 300338(Mmp1b) 300339(Mmp1)
CGE: 100754854
MAUA: 101824185
PLEU: 114708012(Mmp1)
MORG: 121451946
AAMP: 119810622
HGL: 101697620(Mmp1)
CPOC: 100727966
CCAN: 109689286(Mmp1)
DORD: 105980664(Mmp1)
DSP: 122110407(Mmp1)
NCAR: 124959000
OCU: 100009110(MMP1)
OPI: 101527643(MMP1)
TUP: 102489479(MMP1) 102490608
CFA: 489428(MMP1)
CLUD: 112671438(MMP1)
VVP: 112925907
VLG: 121500184(MMP1)
AML: 100478167(MMP1) 100481181
UMR: 103662453(MMP1) 103662455
UAR: 123792352 123792354(MMP1)
MPUF: 101688986(MMP1) 101689258
EJU: 114211360
ZCA: 113915492(MMP1)
MLX: 118013155
FCA: 101083957 101084217(MMP1)
LRUF: 124504840
PTG: 102951453 102970572(MMP1)
BTA: 112441463 281308(MMP1)
BOM: 102264402(MMP1)
CHX: 102170620(MMP1)
OAS: 101120355(MMP1)
ODA: 120876148(MMP1)
SSC: 397320(MMP1)
CFR: 102517049(MMP1)
CBAI: 105067595(MMP1)
CDK: 105087169(MMP1)
VPC: 102528439(MMP1)
BACU: 103009752(MMP1)
LVE: 103089047(MMP1)
OOR: 101270980(MMP1)
DLE: 111167568(MMP1)
PCAD: 102996438(MMP1)
PSIU: 116758693(MMP1)
ECB: 100033896(MMP1)
EPZ: 103552636(MMP1)
EAI: 106843117(MMP1)
MYB: 102253167(MMP1)
MYD: 102770236(MMP1)
MMYO: 118664460(MMP1)
MNA: 107532387(MMP1)
PKL: 118713253(MMP1)
HAI: 109376363
DRO: 112317543(MMP1)
SHON: 118975722(MMP1)
AJM: 119054054(MMP1)
PDIC: 114499949(MMP1)
PHAS: 123805463(MMP1)
MMF: 118627979(MMP1)
RFQ: 117031217(MMP1)
PALE: 102893881(MMP1)
PVP: 105297437
RAY: 107504633(MMP1)
MJV: 108385449(MMP1)
TOD: 119240913(MMP1)
SARA: 101545391(MMP1)
LAV: 100656422(MMP1)
TMU: 101341516
DNM: 101411093(MMP1) 101432285
MDO: 100012472(MMP1)
GAS: 123238994
SHR: 100915062(MMP1)
PCW: 110215019
OAA: 100078975
GGA: 418982(MMP1)
PCOC: 116230604
MGP: 100543241
CJO: 107308399
NMEL: 110389878
APLA: 101798298
ACYG: 106034204
AFUL: 116496881
TGU: 100218575
LSR: 110470054
SCAN: 103827284
PMOA: 120506634
OTC: 121342523
PRUF: 121364174
GFR: 102045551(MMP1)
FAB: 101811360(MMP1)
PHI: 102110938
PMAJ: 107213683
CCAE: 111924335
CCW: 104690063
CBRC: 103617951
ETL: 114067040
ZAB: 102070166
ACHL: 103805364
FPG: 101924590(MMP1)
FCH: 102051111
CLV: 102089808
EGZ: 104128912
NNI: 104023069
PLET: 104617131
PCRI: 104023704
ACUN: 113477011
TALA: 104368301
PADL: 103915454
AFOR: 103895111
ACHC: 115353351
HALD: 104314247
CCRI: 104163037
CSTI: 104555988
EHS: 104508788
CMAC: 104473095
MUI: 104542490
FGA: 104081956
GSTE: 104255837
LDI: 104351210
MNB: 103774352
OHA: 104333033
NNT: 104409993
DPUB: 104296583
PGUU: 104468559
ACAR: 104532860
AVIT: 104279809
CVF: 104290312
AAM: 106495498
AROW: 112971957
NPD: 112943713
TGT: 104571780
DNE: 112988755
SCAM: 104151761
AMJ: 102563438(MMP8) 102563684(MMP1) 109281824
PSS: 102448178
CMY: 114018917
CABI: 116814901
PVT: 110089072
SUND: 121927281
CTIG: 120313875
TSR: 106552779
PGUT: 117660852
VKO: 123029456
PMUA: 114595663
ZVI: 118084936
GJA: 107119159
STOW: 125430822
XLA: 108708733(mmp1.L) 495287(mmp1.S)
XTR: 594916(mmp1)
NPR: 108795960
RTEM: 120929038
BBEL: 109462004
VEM: 105565628
OSN: 115222658
 » show all
Reference
PMID:2167156
  Authors
Templeton NS, Brown PD, Levy AT, Margulies IM, Liotta LA, Stetler-Stevenson WG
  Title
Cloning and characterization of human tumor cell interstitial collagenase.
  Journal
Cancer Res 50:5431-7 (1990)
  Sequence
[hsa:4312]
Reference
  Authors
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C
  Title
Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.
  Journal
Biochim Biophys Acta 1803:3-19 (2010)
DOI:10.1016/j.bbamcr.2009.07.004
Reference
  Authors
Amalinei C, Caruntu ID, Balan RA
  Title
Biology of metalloproteinases.
  Journal
Rom J Morphol Embryol 48:323-34 (2007)
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