KEGG   ORTHOLOGY: K01440
Entry
K01440                      KO                                     
Symbol
PNC1
Name
nicotinamidase [EC:3.5.1.19]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
map04213  Longevity regulating pathway - multiple species
Reaction
R01268  nicotinamide amidohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K01440  PNC1; nicotinamidase
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    K01440  PNC1; nicotinamidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.19  nicotinamidase
     K01440  PNC1; nicotinamidase
Other DBs
COG: COG1335
GO: 0008936
Genes
SCE: YGL037C(PNC1)
SEUB: DI49_1930
SPAO: SPAR_G01990
AGO: AGOS_AFR466C
ERC: Ecym_1410
KMX: KLMA_40268(PNC1)
LTH: KLTH0H09086g
VPO: Kpol_1041p36
ZRO: ZYRO0G09306g
NCS: NCAS_0A01870(NCAS0A01870)
NDI: NDAI_0D03800(NDAI0D03800)
TPF: TPHA_0F00510(TPHA0F00510)
TBL: TBLA_0C04280(TBLA0C04280)
TGB: HG536_0D04820
TDL: TDEL_0F02750(TDEL0F02750)
KAF: KAFR_0F03650(KAFR0F03650)
KNG: KNAG_0D03760(KNAG0D03760)
ZMK: HG535_0B05490
DHA: DEHA2C13552g
PGU: PGUG_05623
SPAA: SPAPADRAFT_63514
LEL: PVL30_005301(PNC1)
LBG: 92211283(LODBEIA_P60870)
CAL: CAALFM_C703520WA(PNC1)
CTP: CTRG_05150
COT: CORT_0G03890
CDU: CD36_73170
CTEN: 18247876(PNC1)
CLU: CLUG_01659
CLUS: A9F13_13g01023
CAUR: CJI96_0002795
ASAU: 88171485(PUMCH_000416)
PPA: PAS_chr3_0361
PKZ: C5L36_0B08530
BNN: FOA43_004158
BBRX: BRETT_002789
OPA: HPODL_01677
YLI: 2906381(YALI2_A00336g)
SLB: AWJ20_4246(PNC1)
CNE: CNA07780
CNB: CNBA7610
CNG: CNAG_00800
CGI: CGB_A9180C
CDEU: CNBG_1134
CDEC: 89988405(IAS62_001631)
CTEG: 91987784(I308_100926)
CBAS: 91980960(I312_100912)
CDEP: 91089090(L203_104881)
KMG: 30166516(I203_100765)
KNE: 92181578(IAR55_004320)
KDJ: 28971688(I303_107998)
KBI: 30206085(I302_102990)
KPIN: 30175573(I206_106400)
KSH: 87959683(IL334_007553)
KER: 91105383(V865_006582)
KEP: 91097775(L201_007106)
CCAC: CcaHIS019_0510330(CcaverHIS019_0510330)
RSX: RhiXN_04254
PTRC: PtA15_5A242
PSTR: Pst134EA_009474 Pst134EA_031404
 » show all
Reference
PMID:11816029
  Authors
Ghislain M, Talla E, Francois JM
  Title
Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1.
  Journal
Yeast 19:215-24 (2002)
DOI:10.1002/yea.810
Reference
PMID:12736687
  Authors
Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA
  Title
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.
  Journal
Nature 423:181-5 (2003)
DOI:10.1038/nature01578
  Sequence
[sce:YGL037C]
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