KEGG   ORTHOLOGY: K01582
Entry
K01582                      KO                                     
Symbol
E4.1.1.18, ldcC, cadA
Name
lysine decarboxylase [EC:4.1.1.18]
Pathway
map00310  Lysine degradation
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
Module
M00956  Lysine degradation, bacteria, L-lysine => succinate
Reaction
R00462  L-lysine carboxy-lyase (cadaverine-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K01582  E4.1.1.18, ldcC, cadA; lysine decarboxylase
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K01582  E4.1.1.18, ldcC, cadA; lysine decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.18  lysine decarboxylase
     K01582  E4.1.1.18, ldcC, cadA; lysine decarboxylase
Other DBs
COG: COG1982
GO: 0008923
Genes
ECO: b0186(ldcC) b4131(cadA)
ECJ: JW0181(ldcC) JW4092(cadA)
ECD: ECDH10B_0166(ldcC) ECDH10B_4324(cadA)
EBW: BWG_0178(ldcC) BWG_3845(cadA)
ECOK: ECMDS42_0173(ldcC) ECMDS42_3571(cadA)
ECOC: C3026_00855 C3026_22330
ECE: Z0198(ldcC) Z5734(cadA)
ECS: ECs_0188(cadA_1) ECs_5113(cadA)
ECF: ECH74115_0196(ldcC1) ECH74115_5647(ldcC2)
ETW: ECSP_0185(ldcC) ECSP_5231(cadA)
EOI: ECO111_0187(ldcC)
EOJ: ECO26_0188(ldcC) ECO26_5243(cadA)
EOH: ECO103_0184(ldcC) ECO103_4883(cadA)
ECOO: ECRM13514_0194(ldcC) ECRM13514_5348(cadA)
ECOH: ECRM13516_0196(ldcC) ECRM13516_5016(cadA)
ECK: EC55989_0180(ldcC) EC55989_4624(cadA)
ECG: E2348C_0191(ldcC) E2348C_4458(cadA)
EOK: G2583_0189(ldcC) G2583_4958(cadA)
ENA: ECNA114_0176(ldcC) ECNA114_4317(cadA)
ECOS: EC958_0332(ldcC) EC958_4620(cadA)
ECV: APECO1_1801(ldcC) APECO1_2322(cadA)
ECX: EcHS_A0188(ldcC1) EcHS_A4372(ldcC2)
ECM: EcSMS35_0197(ldcC1) EcSMS35_4600(ldcC2)
ECR: ECIAI1_0186(ldcC) ECIAI1_4364(cadA)
ECQ: ECED1_0192(ldcC) ECED1_4867(cadA)
EUM: ECUMN_0183(ldcC) ECUMN_4665(cadA)
ECT: ECIAI39_0189(ldcC) ECIAI39_4560(cadA)
EOC: CE10_0188(ldcC) CE10_4850(cadA)
EBR: ECB_00184(ldcC) ECB_04002(cadA)
EBL: ECD_00184(ldcC) ECD_04002(cadA)
EBE: B21_00183(ldcC) B21_03964(cadA)
ECI: UTI89_C0201(ldcC) UTI89_C4728(cadA)
EIH: ECOK1_4643(ldcL)
ECZ: ECS88_0197(ldcC) ECS88_4635(cadA)
ECC: c0224(ldcC) c5140(cadA)
ELO: EC042_0184(ldcC) EC042_4497(cadA)
EKF: KO11_00900(ldcC) KO11_01675(cadA)
EAB: ECABU_c01990(ldcC) ECABU_c46850(cadA)
ELW: ECW_m0182(ldcC) ECW_m4492(cadA)
ELL: WFL_00900(ldcC) WFL_21855(cadA)
ELC: i14_0206(ldcC) i14_4725(cadA)
ELD: i02_0206(ldcC) i02_4725(cadA)
ELP: P12B_c0174(ldcC) P12B_c4231(cadA)
ELF: LF82_0254(cadA) LF82_1172(ldcC)
ECOI: ECOPMV1_00192(ldcC) ECOPMV1_04591(cadA)
EFE: EFER_0209(ldcC) EFER_1900(cadA)
EAL: EAKF1_ch2295c(ldcC2)
STY: STY0259(ldcC) STY2806(cadA)
STT: t0236(ldcC) t0297(cadA)
STM: STM0234(ldcC) STM2559(cadA)
SEO: STM14_0276(ldcC) STM14_3138(cadA)
SEY: SL1344_0235(ldcC) SL1344_2521(cadA)
SEJ: STMUK_0236(ldcC) STMUK_2591(cadA)
SEB: STM474_0243(ldcC) STM474_2664(cadA)
SEF: UMN798_0255(ldcC) UMN798_2763(cadA)
SENR: STMDT2_02361(ldcC) STMDT2_25201(cadA)
SEND: DT104_02391(ldcC) DT104_26111(cadA)
SPT: SPA0241(ldcC) SPA0307(cadA)
SEI: SPC_0250(ldcC) SPC_1091(cadA)
SEC: SCH_0234(ldcC) SCH_2554(cadA)
SED: SeD_A0256(ldcC) SeD_A2935
SEG: SG0238(ldcC) SG2596(cadA)
SEL: SPUL_0254(ldcC) SPUL_0315(cadA)
SEGA: SPUCDC_0254(ldcC) SPUCDC_0315(cadA)
SET: SEN0241(ldcC) SEN2539(cadA)
SENB: BN855_2500(ldcC) BN855_26490
SBG: SBG_0225(ldcC) SBG_2334(cadA)
SFL: SF0176(ldcC)
SFX: S0179(ldcC)
SFV: SFV_0169(ldcC)
SFE: SFxv_0186(ldcC)
SFN: SFy_0240
SFS: SFyv_0244
SFT: NCTC1_00182(ldcC1)
SSN: SSON_0199(ldcC)
SBC: SbBS512_E0179(ldcC1)
ENC: ECL_00989
ECLX: LI66_04155
ECLY: LI62_04670
ECLZ: LI64_04330
ECLO: ENC_47090
EEC: EcWSU1_00798(ldcC)
ESA: ESA_03153
CSK: ES15_3144(ldcC)
CTU: CTU_08150(ldcC)
KPN: KPN_00199(ldcC) KPN_00500(cadA)
KPU: KP1_1043(ldcC) KP1_1410(cadA)
KPR: KPR_1130(ldcC) KPR_4061
KPX: PMK1_02507(ldcC) PMK1_02826(cadA)
KPNK: BN49_1542 BN49_4138(ldcC)
KPE: KPK_4092 KPK_4534(ldcC)
KOE: A225_1471
RTG: NCTC13098_06062(ldcC)
CRO: ROD_01941(ldcC)
CKO: CKO_03180
CBRA: A6J81_12420(ldcC)
CPOT: FOB25_06660(ldcC)
CSED: JY391_17405(ldcC)
CAMA: F384_00965
CAF: AL524_21535(ldcC)
CIF: AL515_05675(ldcC)
CIE: AN232_25540(ldcC)
CTEL: GBC03_24895(ldcC)
CITZ: E4Z61_12635(ldcC)
CARS: E1B03_05430(ldcC)
CIX: M4I31_19225(ldcC)
CIB: HF677_019010(ldcC)
CITR: GUC46_19295(ldcC)
EBT: EBL_c28010(cadA1) EBL_c31760(cadA2)
CLAP: NCTC11466_03741(ldcC)
KIE: NCTC12125_02837(ldcC)
KLU: K7B04_00485(ldcC) K7B04_23410(cadA)
KCY: RIN60_18495(ldcC)
LER: GNG29_04390(ldcC)
LEA: GNG26_03880(ldcC)
PSGC: G163CM_17020(cadA) G163CM_27130(ldcC)
SUPE: P0H77_05140(ldcC) P0H77_15930(cadA)
TOE: QMG90_05085(cadA) QMG90_17300(ldcC)
EBB: F652_2458 F652_3828(cadB)
PSTS: E05_03420
YEN: YE3267(ldcC)
YEY: Y11_41191
YEW: CH47_276(ldcC)
YET: CH48_717
YEE: YE5303_06261(ldcC)
YAL: AT01_1580
YIN: CH53_2737
YRU: BD65_654(cadA)
SMAR: SM39_3366(cadA) SM39_3371(ldcC)
SMAC: SMDB11_3155(cadA) SMDB11_3161(ldcC)
SRL: SOD_c37380(ldcC)
SPLY: Q5A_019915(ldcC)
SMAF: D781_3508
SFJ: SAMEA4384070_3887(ldcC)
SOF: NCTC11214_02873(ldcC_2) NCTC11214_02880(cadA)
SGRI: SGBXF1_03876(cadA) SGBXF1_03883(ldcC)
RAA: Q7S_04150
SOD: Sant_0913(ldcC)
PES: SOPEG_3382(ldcC)
EAM: EAMY_2742(cadA)
EAY: EAM_0836(ldcC)
ETA: ETA_09070(cadA)
EPY: EpC_08860
EPR: EPYR_00935(cadA)
EBI: EbC_08270
ERWI: GN242_17040(ldcC)
EGE: EM595_0820(ldcC)
PAM: PANA_0810(ldcC)
PLF: PANA5342_3498(ldcC)
PAJ: PAJ_0157(ldcC)
PVA: Pvag_0219(ldcC)
PSTW: DSJ_06725
PEY: EE896_15495(ldcC)
MINT: C7M51_00148(ldcC)
MTHI: C7M52_02571(ldcC)
PMAK: PMPD1_0962
ETE: ETEE_1240(ldcC) ETEE_2039(ldcC) ETEE_2518(ldcC)
ETR: ETAE_0284(cadA1) ETAE_0757(cadA2) ETAE_3006(cadA3)
HSO: HS_1007(cadA)
ADP: NCTC12871_01111(cadA)
PBAN: AC062_2065
VCH: VC_0281
VCS: MS6_0145
VCI: O3Y_01305
VCO: VC0395_A2658(cadA)
VCR: VC395_0310(cadA)
VCM: VCM66_0266(cadA)
VVU: VV1_2060
VVY: VV2381
VPA: VP2890
VPB: VPBB_2740
VAG: N646_1979
VPL: SA104470976_02458(cadA)
VFI: VF_2057(cadA)
VSA: VSAL_I2491(cadA)
MVS: MVIS_4400(cadA)
MMAA: FR932_18035(cadA)
LFA: LFA_0253(ldcC)
LCJ: NCTC11976_02922(cadA)
FTU: FTT_0406(cadA)
FTQ: RO31_0456(cadA)
FTF: FTF0406(cadA)
FTW: FTW_1667(cadA)
FTT: FTV_0376(cadA)
FTG: FTU_0460(cadA)
FTL: FTL_0476
FTH: FTH_0474(cadA)
FTA: FTA_0502
FTS: F92_02580
FTI: FTS_0478(cadA)
FTC: DA46_219(cadA)
FTV: CH67_777(cadA)
FTZ: CH68_511(cadA)
FTN: FTN_0504
FTX: AW25_1525(cadA)
FTD: AS84_180(cadA)
FTY: CH70_1559(cadA)
FPH: Fphi_0341
FPT: BZ13_1733(cadA)
FPI: BF30_519(cadA)
FPM: LA56_1846(cadA)
FPX: KU46_1035(cadA)
FPZ: LA55_502(cadA)
FPJ: LA02_1952(cadA)
FNA: OOM_1068
FRC: KX01_1834(cadA)
FRL: FIP56_08255(ldcC)
AFRI: E3E15_03030(ldcC)
AII: E4K63_03290(ldcC)
AHA: AHA_1192
ASA: ASA_3141(cadA)
AVR: B565_3003
ASR: WL1483_1742(cadA)
AEL: NCTC12917_03192(cadA)
ASIM: FE240_11630(cadA)
ECOR: SAMEA4412678_1910(cadA)
PPIO: CE91St28_08010(cadA)
PYY: RAH42_04980(ldcC)
 » show all
Reference
PMID:9339543
  Authors
Yamamoto Y, Miwa Y, Miyoshi K, Furuyama J, Ohmori H
  Title
The Escherichia coli ldcC gene encodes another lysine decarboxylase, probably a constitutive enzyme.
  Journal
Genes Genet Syst 72:167-72 (1997)
DOI:10.1266/ggs.72.167
  Sequence
[ecj:JW0181]
LinkDB

KEGG   ENZYME: 4.1.1.18
Entry
EC 4.1.1.18                 Enzyme                                 
Name
lysine decarboxylase;
L-lysine carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
L-lysine carboxy-lyase (cadaverine-forming)
Reaction(IUBMB)
L-lysine = cadaverine + CO2 [RN:R00462]
Reaction(KEGG)
R00462
Substrate
L-lysine [CPD:C00047]
Product
cadaverine [CPD:C01672];
CO2 [CPD:C00011]
Comment
A pyridoxal-phosphate protein. Also acts on 5-hydroxy-L-lysine.
History
EC 4.1.1.18 created 1961
Pathway
ec00310  Lysine degradation
ec00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K01582  lysine decarboxylase
Genes
ECOb0186(ldcC) b4131(cadA)
ECJJW0181(ldcC) JW4092(cadA)
ECDECDH10B_0166(ldcC) ECDH10B_4324(cadA)
EBWBWG_0178(ldcC) BWG_3845(cadA)
ECOKECMDS42_0173(ldcC) ECMDS42_3571(cadA)
ECOCC3026_00855 C3026_22330
ECEZ0198(ldcC) Z5734(cadA)
ECSECs_0188(cadA_1) ECs_5113(cadA)
ECFECH74115_0196(ldcC1) ECH74115_5647(ldcC2)
ETWECSP_0185(ldcC) ECSP_5231(cadA)
ELXCDCO157_0186 CDCO157_4798
EOIECO111_0187(ldcC)
EOJECO26_0188(ldcC) ECO26_5243(cadA)
EOHECO103_0184(ldcC) ECO103_4883(cadA)
ECOOECRM13514_0194(ldcC) ECRM13514_5348(cadA)
ECOHECRM13516_0196(ldcC) ECRM13516_5016(cadA)
ESLO3K_20640 O3K_23215
ESOO3O_02145 O3O_04740
ESMO3M_20540 O3M_23135
ECKEC55989_0180(ldcC) EC55989_4624(cadA)
ECGE2348C_0191(ldcC) E2348C_4458(cadA)
EOKG2583_0189(ldcC) G2583_4958(cadA)
ELRECO55CA74_00910 ECO55CA74_23770
ELHETEC_0181 ETEC_4442
ECWEcE24377A_0190(ldcC) EcE24377A_4686
EUNUMNK88_191 UMNK88_4998
ECPECP_0194 ECP_0327 ECP_4375
ENAECNA114_0176(ldcC) ECNA114_4317(cadA)
ECOSEC958_0332(ldcC) EC958_4620(cadA)
ECVAPECO1_1801(ldcC) APECO1_2322(cadA)
ECOAAPECO78_01590 APECO78_04360
ECXEcHS_A0188(ldcC1) EcHS_A4372(ldcC2)
ECMEcSMS35_0197(ldcC1) EcSMS35_4600(ldcC2)
ECYECSE_0185 ECSE_4431
ECRECIAI1_0186(ldcC) ECIAI1_4364(cadA)
ECQECED1_0192(ldcC) ECED1_4867(cadA)
EUMECUMN_0183(ldcC) ECUMN_4665(cadA)
ECTECIAI39_0189(ldcC) ECIAI39_4560(cadA)
EOCCE10_0188(ldcC) CE10_4850(cadA)
EBRECB_00184(ldcC) ECB_04002(cadA)
ECOBC3029_02345 C3029_04700
EBLECD_00184(ldcC) ECD_04002(cadA)
EBEB21_00183(ldcC) B21_03964(cadA)
EBDECBD_3433 ECBD_3899
ECIUTI89_C0201(ldcC) UTI89_C4728(cadA)
EIHECOK1_4643(ldcL)
ECZECS88_0197(ldcC) ECS88_4635(cadA)
ECCc0224(ldcC) c5140(cadA)
ELOEC042_0184(ldcC) EC042_4497(cadA)
ELNNRG857_00950 NRG857_20725
ESEECSF_0201 ECSF_4020
ECLEcolC_3474 EcolC_3896
EKOEKO11_3732 EKO11_4187
EKFKO11_00900(ldcC) KO11_01675(cadA)
EABECABU_c01990(ldcC) ECABU_c46850(cadA)
EDHEcDH1_3417 EcDH1_3860
EDJECDH1ME8569_0179(ldcC) ECDH1ME8569_3991(cadA)
ELUUM146_20895 UM146_23735
ELWECW_m0182(ldcC) ECW_m4492(cadA)
ELLWFL_00900(ldcC) WFL_21855(cadA)
ELCi14_0206(ldcC) i14_4725(cadA)
ELDi02_0206(ldcC) i02_4725(cadA)
ELPP12B_c0174(ldcC) P12B_c4231(cadA)
ELFLF82_0254(cadA) LF82_1172(ldcC)
ECOLLY180_00900 LY180_21700
ECOIECOPMV1_00192(ldcC) ECOPMV1_04591(cadA)
ECOJP423_00990 P423_23025
EFEEFER_0209(ldcC) EFER_1900(cadA)
EALEAKF1_ch2295c(ldcC2)
EMAC1192_19340
ESZFEM44_12485
STYSTY0259(ldcC) STY2806(cadA)
STTt0236(ldcC) t0297(cadA)
SEXSTBHUCCB_2580 STBHUCCB_3190
SENTTY21A_01215 TY21A_01510
STMSTM0234(ldcC) STM2559(cadA)
SEOSTM14_0276(ldcC) STM14_3138(cadA)
SEVSTMMW_02401 STMMW_25761
SEYSL1344_0235(ldcC) SL1344_2521(cadA)
SEMSTMDT12_C02350 STMDT12_C25790
SEJSTMUK_0236(ldcC) STMUK_2591(cadA)
SEBSTM474_0243(ldcC) STM474_2664(cadA)
SEFUMN798_0255(ldcC) UMN798_2763(cadA)
SETUSTU288_01180 STU288_09155
SETCCFSAN001921_03975 CFSAN001921_16230
SENRSTMDT2_02361(ldcC) STMDT2_25201(cadA)
SENDDT104_02391(ldcC) DT104_26111(cadA)
SENICY43_01175 CY43_13655
SEENSE451236_07190 SE451236_19020
SPTSPA0241(ldcC) SPA0307(cadA)
SEKSSPA0233 SSPA0290
SPQSPAB_00299 SPAB_00369
SEISPC_0250(ldcC) SPC_1091(cadA)
SECSCH_0234(ldcC) SCH_2554(cadA)
SEHSeHA_C0272 SeHA_C2822
SHBSU5_03156 SU5_0883
SENHCFSAN002069_07975 CFSAN002069_18970
SEEHSEEH1578_10290 SEEH1578_22120
SEESNSL254_A0256 SNSL254_A2760
SENNSN31241_12290 SN31241_36690
SEWSeSA_A0261 SeSA_A2801
SEASeAg_B0275 SeAg_B2718
SENSQ786_01230 Q786_12670
SEDSeD_A0256(ldcC) SeD_A2935
SEGSG0238(ldcC) SG2596(cadA)
SELSPUL_0254(ldcC) SPUL_0315(cadA)
SEGASPUCDC_0254(ldcC) SPUCDC_0315(cadA)
SETSEN0241(ldcC) SEN2539(cadA)
SENAAU38_01195 AU38_12865
SENOAU37_01195 AU37_12875
SENVAU39_01195 AU39_12875
SENQAU40_01360 AU40_14470
SENLIY59_01220 IY59_13215
SENJCFSAN001992_09805 CFSAN001992_20740
SEECCFSAN002050_07710 CFSAN002050_19745
SEEBSEEB0189_006755 SEEB0189_018135
SEEPI137_01135 I137_01445
SENBBN855_2500(ldcC) BN855_26490
SENEIA1_01260 IA1_12795
SENCSEET0819_08100 SEET0819_20250
SESSARI_00317 SARI_02768
SBGSBG_0225(ldcC) SBG_2334(cadA)
SBZA464_239 A464_2671
SBVN643_01095 N643_11355
SALZEOS98_06150 EOS98_18035
SFLSF0176(ldcC)
SFXS0179(ldcC)
SFVSFV_0169(ldcC)
SFESFxv_0186(ldcC)
SFNSFy_0240
SFSSFyv_0244
SFTNCTC1_00182(ldcC1)
SSNSSON_0199(ldcC)
SBCSbBS512_E0179(ldcC1)
SDZAsd1617_00249 Asd1617_05863
SHQA0259_02295 A0259_04775
ENCECL_00989
ENLA3UG_04145
ECLGEC036_08150
ECLEECNIH2_05080
ECLNECNIH4_18610
ECLIECNIH5_04145
ECLXLI66_04155
ECLYLI62_04670
ECLZLI64_04330
ECLOENC_47090
EHMAB284_20805
EXFBFV63_04115
ECLAECNIH3_04135
ECLCECR091_04115
EAUDI57_14485
EKBBFV64_03920
ENOECENHK_04380
EECEcWSU1_00798(ldcC)
ELGBH714_18810
ECANCWI88_18000
ERNBFV67_03940
ECLSLI67_005085
ECHGFY206_04825
ESHC1N69_04025
EPTHWQ17_08430
ENTEnt638_0724
EASEntas_0783
ENRH650_19710
ENXNI40_003950
ENFAKI40_4103
LNICWR52_08040
EBGFAI37_02465
ENZG0034_04185
ENSHWQ15_12565
ENKLOC22_14965
EHUD5067_0018735
EMORL6Y89_03940
ENBELK40_04745
EQUOM418_04030
EPUQVH39_04060
EDYF0320_03735
ESAESA_03153
CSKES15_3144(ldcC)
CSZCSSP291_14590
CSJCSK29544_00081
CCONAFK62_04100
CDMAFK67_04085
CSIP262_04644
CMJAFK66_015640
CUIAFK65_04025
CMWAFK63_14530
CTUCTU_08150(ldcC)
KPNKPN_00199(ldcC) KPN_00500(cadA)
KPUKP1_1043(ldcC) KP1_1410(cadA)
KPMKPHS_09330 KPHS_13090
KPPA79E_3758 A79E_4091
KPHKPNIH24_04670 KPNIH24_22225
KPZKPNIH27_04470 KPNIH27_06100
KPVKPNIH29_04865 KPNIH29_06750
KPWKPNIH30_04895 KPNIH30_06760
KPYKPNIH31_03155 KPNIH31_06665
KPGKPNIH32_04900 KPNIH32_06865
KPCKPNIH10_04645 KPNIH10_06580
KPQKPR0928_04655 KPR0928_06495
KPTVK055_2051(cadA) VK055_2366
KPOKPN2242_03445 KPN2242_05280
KPRKPR_1130(ldcC) KPR_4061
KPJN559_3848 N559_4214
KPID364_00960 D364_02570
KPAKPNJ1_04113 KPNJ1_04521
KPSKPNJ2_04136 KPNJ2_04473
KPXPMK1_02507(ldcC) PMK1_02826(cadA)
KPBFH42_21840 FH42_23450
KPNEKU54_019895
KPNULI86_19725 LI86_21690
KPNKBN49_1542 BN49_4138(ldcC)
KVAKvar_3879 Kvar_4182
KPEKPK_4092 KPK_4534(ldcC)
KPKA593_15410 A593_16900
KVDKR75_12790 KR75_14335
KVQSP68_19465 SP68_20990
KOXKOX_11535 KOX_13270
KOEA225_1471
KOYJ415_24280 J415_26175
KOMHR38_10265 HR38_12020
KMIVW41_03900
KOKKONIH1_05265 KONIH1_07220
KOCAB185_28820 AB185_30910
KQUAVR78_09245 AVR78_11005
EAEEAE_11730 EAE_13250
EARCCG31329 CCG31633
KQVB8P98_21020 B8P98_22610
KLLBJF97_05810 BJF97_07665
KLWDA718_21060 DA718_23200
KARLGL98_18840(cadA) LGL98_20420
KGRJJJ10_20840(cadA) JJJ10_22795
KPASLUW96_11735 LUW96_14055(cadA)
KLCK7H21_20855(cadA) K7H21_22935
KLMBWI76_05300 BWI76_07195
REEelectrica_03794(cadA) electrica_04147(ldcC)
RORRORB6_12665 RORB6_14180
RONTE10_06740 TE10_08330
RPLNB1209_20335
RAODSD31_19215 DSD31_20850
RTGNCTC13098_06062(ldcC)
CROROD_01941(ldcC)
CKOCKO_03180
CFDCFNIH1_10610
CBRAA6J81_12420(ldcC)
CWECO701_17500
CYOCD187_19555
CPOTFOB25_06660(ldcC)
CFQC2U38_04260
CSEDJY391_17405(ldcC)
CAMAF384_00965
CAFAL524_21535(ldcC)
CIFAL515_05675(ldcC)
CFARCI104_05380
CIRC2U53_03955
CIEAN232_25540(ldcC)
CPARCUC49_00925
CTELGBC03_24895(ldcC)
CITZE4Z61_12635(ldcC)
CARSE1B03_05430(ldcC)
CIXM4I31_19225(ldcC)
CIBHF677_019010(ldcC)
CITRGUC46_19295(ldcC)
EBTEBL_c28010(cadA1) EBL_c31760(cadA2)
CNTJT31_08370
CEMLH23_09355
CENLH86_09410
CLAPNCTC11466_03741(ldcC)
PGELG71_07875 LG71_10805
ESCEntcl_1196 Entcl_3519 Entcl_3551
KLEAO703_04185 AO703_15850
KSAC813_10860
KORAWR26_20590
KRDA3780_03150
KCOBWI95_01405
KOTEH164_18130
KPSEIP581_04170
KOBHF650_04670
KOOO9K67_20245
KIENCTC12125_02837(ldcC)
KASKATP_11200(cadA) KATP_36880
KLUK7B04_00485(ldcC) K7B04_23410(cadA)
KCYRIN60_18495(ldcC)
LAXAPT61_18175
LEIC2U54_09175
LEHC3F35_07590
LEEDVA44_19705
LERGNG29_04390(ldcC)
LEAGNG26_03880(ldcC)
LPNUKQ929_16750
LEYDVA43_13565
LAZA8A57_04115
LEFLJPFL01_0813
LEWDAI21_00310
BUFD8682_09495 D8682_11040
BAGEBADSM9389_33690
BFTMNO13_18190(cadA) MNO13_19710
BSELRHD99_18100(cadA) RHD99_19645
AHNNCTC12129_00982(ldcC) NCTC12129_00987(cadA)
ASUBNLZ15_17890
YREHEC60_13890(cadA) HEC60_22070
SGOEA8O29_018670
KINAB182_20835
PDZHHA33_23385
METYMRY16398_46130
PSHISAMEA2665130_0737(cadA_1) SAMEA2665130_1220(cadA_2) SAMEA2665130_2471(cadA_4)
PSGCG163CM_17020(cadA) G163CM_27130(ldcC)
SCOLKFZ77_03940
PVJLMA04_04590(cadA) LMA04_08165 LMA04_18410(cadA)
SUPEP0H77_05140(ldcC) P0H77_15930(cadA)
TOEQMG90_05085(cadA) QMG90_17300(ldcC)
EBFD782_2731 D782_3685
EBCC2U52_02475
EBUCUC76_08980 CUC76_10615
EBBF652_2458 F652_3828(cadB)
PSTSE05_03420
YENYE3267(ldcC)
YEPYE105_C0987
YEYY11_41191
YEWCH47_276(ldcC)
YETCH48_717
YEFFORC2_0883
YEEYE5303_06261(ldcC)
YALAT01_1580
YINCH53_2737
YRUBD65_654(cadA)
YRBUGYR_03485
YELLC20_01213
YCAF0T03_16955
YASN0H69_07935
YKIHRD70_22055
YEGPL78_08555
SMARSM39_3366(cadA) SM39_3371(ldcC)
SMACSMDB11_3155(cadA) SMDB11_3161(ldcC)
SMWSMWW4_v1c38880 SMWW4_v1c38920
SPESpro_3767 Spro_3773
SRRSerAS9_3962
SRLSOD_c37380(ldcC)
SRYM621_20085
SPLYQ5A_019915(ldcC)
SRSSerAS12_3963
SRASerAS13_3963
SMAFD781_3508
SLQM495_19635 M495_19665
SERFL085_09230 L085_09250
SERSSERRSCBI_18820 SERRSCBI_18840
SFWWN53_01640 WN53_01660
SFGAV650_24400 AV650_24420
SRZAXX16_1568
SERMCLM71_18430
SQUE4343_21565 E4343_21595
SFJSAMEA4384070_3887(ldcC)
SOFNCTC11214_02873(ldcC_2) NCTC11214_02880(cadA)
SSURATE40_016110 ATE40_016130
SURIJ0X03_04535 J0X03_04555(cadA)
SRHZFO014_15790
SENPKHA73_18925
SNEMNLX84_19575(cadA) NLX84_19595
SNEVOI978_12535 OI978_12555(cadA)
SGRISGBXF1_03876(cadA) SGBXF1_03883(ldcC)
SSARSSARUM_003751(cadA) SSARUM_003755
RAHRahaq_0880
RACEJHW33_21085
RAQRahaq2_0943
RAAQ7S_04150
ROXBV494_21355
RVCJ9880_12030
RBONQNM34_04495
RIUI2123_06380
GQUAWC35_16875
EAMEGXP68_03665
RBADH2866_03815
RCBO1V66_21615
CARUP0E69_04365
NIGC1N62_03410
SODSant_0913(ldcC)
PESSOPEG_3382(ldcC)
SLIGGTU79_05185
EAMEAMY_2742(cadA)
EAYEAM_0836(ldcC)
ETAETA_09070(cadA)
EPYEpC_08860
EPREPYR_00935(cadA)
EBIEbC_08270
ERJEJP617_02020
EPECI789_14375
ERWIGN242_17040(ldcC)
ERPLJN55_18775
EPIQ3V30_17205
ETORIN69_04635
EGEEM595_0820(ldcC)
PAMPANA_0810(ldcC)
PLFPANA5342_3498(ldcC)
PAJPAJ_0157(ldcC)
PAQPAGR_g3389
PVAPvag_0219(ldcC)
PAGGAL522_08045
PAOPat9b_0767
KLNLH22_18410
PANTPSNIH1_08785
PANPPSNIH2_13940
PAGCBEE12_10780
PSTWDSJ_06725
PALHB1H58_02985 B1H58_15020
PANSFCN45_03890
PEYEE896_15495(ldcC)
PDISD8B20_03730
PERLAC65_02975
PJIKTJ90_15355
PANOOJ965_17240
KPIEN5580_14745
PALFK6R05_15090
PPHOCTZ24_03970
PDIPKFZ74_16105
PGZC2E15_04825
PCDC2E16_04750
MINTC7M51_00148(ldcC)
MTHIC7M52_02571(ldcC)
MHANK6958_04495
PMAKPMPD1_0962
EICNT01EI_0291 NT01EI_0859 NT01EI_3413
ETDETAF_0246 ETAF_0700 ETAF_2734
ETEETEE_1240(ldcC) ETEE_2039(ldcC) ETEE_2518(ldcC)
ETRETAE_0284(cadA1) ETAE_0757(cadA2) ETAE_3006(cadA3)
ETCETAC_01205 ETAC_03665 ETAC_14470
EDWQY76_05325 QY76_16540
EDLAAZ33_01275 AAZ33_03585 AAZ33_15915
EHOA9798_12765 A9798_15210
HAVAT03_02990 AT03_17370
HPARAL518_02475 AL518_09050
OPODSM2777_07875 DSM2777_23350
HSOHS_1007(cadA)
ADPNCTC12871_01111(cadA)
RHEYFEE42_02990
RHAEIHV77_11655
PBANAC062_2065
VCHVC_0281
VCFIR04_06305
VCSMS6_0145
VCEVch1786_I2565
VCQEN18_18275
VCJVCD_001340
VCIO3Y_01305
VCOVC0395_A2658(cadA)
VCRVC395_0310(cadA)
VCMVCM66_0266(cadA)
VCLVCLMA_A0246
VCXVAA049_3416
VCZVAB027_3565
VVUVV1_2060
VVYVV2381
VVMVVMO6_00934
VVLVV93_v1c20890
VPAVP2890
VPBVPBB_2740
VPKM636_22935
VPFM634_00980
VPHVPUCM_2987
VHAVIBHAR_00205
VCAM892_11625
VAGN646_1979
VEXVEA_002189
VDBAL552_23360
VHRAL538_08555
VOWA9237_09215
VROBSZ04_24370
VMIAL543_10425
VSHBSZ05_07320
VQICCZ37_12145
VAFD1115_00885
VNLD3H41_15720
VPLSA104470976_02458(cadA)
VTICEQ48_17635
VMTQYQ96_12475
VISVspSTUT16_01540
VIOAB2S62_01135
VFIVF_2057(cadA)
VFMVFMJ11_2162
VSAVSAL_I2491(cadA)
PDSCAY62_01575
MVSMVIS_4400(cadA)
MMAAFR932_18035(cadA)
LFALFA_0253(ldcC)
LCJNCTC11976_02922(cadA)
FTUFTT_0406(cadA)
FTQRO31_0456(cadA)
FTFFTF0406(cadA)
FTWFTW_1667(cadA)
FTRNE061598_02265
FTTFTV_0376(cadA)
FTGFTU_0460(cadA)
FTLFTL_0476
FTHFTH_0474(cadA)
FTAFTA_0502
FTSF92_02580
FTIFTS_0478(cadA)
FTOX557_02565
FTCDA46_219(cadA)
FTVCH67_777(cadA)
FTZCH68_511(cadA)
FTNFTN_0504
FTXAW25_1525(cadA)
FTDAS84_180(cadA)
FTYCH70_1559(cadA)
FCFFNFX1_0489
FCNFN3523_0462
FHIFSC454_02330
FPHFphi_0341
FPTBZ13_1733(cadA)
FPIBF30_519(cadA)
FPMLA56_1846(cadA)
FPXKU46_1035(cadA)
FPZLA55_502(cadA)
FPJLA02_1952(cadA)
FRTF7308_1833
FNAOOM_1068
FNLM973_02955
FRFLO80_08140
FHACDV26_08585
FRXF7310_08080
FRMBBG19_1293
FRCKX01_1834(cadA)
FADCDH04_07890
FMIF0R74_00925
FOOCGC45_06490
FNNFSC774_00820
FSRKQR59_02465
FRLFIP56_08255(ldcC)
FGUSD28_06380
AFRIE3E15_03030(ldcC)
AIIE4K63_03290(ldcC)
AHAAHA_1192
AHYAHML_06345
AHDAI20_13250
AHRV428_06570
AHPV429_06570
AHJV469_16780
AHHRY45_06390
AHIVU14_16715
AAJBOQ57_05790
ASAASA_3141(cadA)
AEOO23A_p2424
AVRB565_3003
AVOAMS64_17760
ASRWL1483_1742(cadA)
ADHCK627_20175
AEMCK911_11755
AELNCTC12917_03192(cadA)
ASIMFE240_11630(cadA)
AALLI6G90_00025
AJDI6H43_05070
AEJE5E97_10595
ABESIU367_16005
ECORSAMEA4412678_1910(cadA)
EEXEZJ17_05575
SUTKFG381_04680
SWSI6J16_01630
PPIOCE91St28_08010(cadA)
PYYRAH42_04980(ldcC)
 » show all
Reference
1  [PMID:16747785]
  Authors
Gale EF, Epps HM.
  Title
Studies on bacterial amino-acid decarboxylases: 1. l(+)-lysine decarboxylase.
  Journal
Biochem J 38:232-42 (1944)
DOI:10.1042/bj0380232
Reference
2  [PMID:5762458]
  Authors
Soda K, Moriguchi M.
  Title
Crystalline lysine decarboxylase.
  Journal
Biochem Biophys Res Commun 34:34-9 (1969)
DOI:10.1016/0006-291X(69)90524-5
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.18
IUBMB Enzyme Nomenclature: 4.1.1.18
ExPASy - ENZYME nomenclature database: 4.1.1.18
BRENDA, the Enzyme Database: 4.1.1.18
CAS: 9024-76-4
LinkDB

KEGG   REACTION: R00462
Entry
R00462                      Reaction                               
Name
L-lysine carboxy-lyase (cadaverine-forming)
Definition
L-Lysine <=> Cadaverine + CO2
Equation
Reaction class
RC00299  C00047_C01672
Enzyme
Pathway
rn00310  Lysine degradation
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Module
M00956  Lysine degradation, bacteria, L-lysine => succinate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.18
     R00462  L-Lysine <=> Cadaverine + CO2
Orthology
K01582  lysine decarboxylase [EC:4.1.1.18]
Other DBs
RHEA: 22355
LinkDB

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