Entry |
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Name |
lysine decarboxylase;
L-lysine carboxy-lyase
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Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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Sysname |
L-lysine carboxy-lyase (cadaverine-forming)
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Reaction(IUBMB) |
L-lysine = cadaverine + CO2 [RN: R00462]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A pyridoxal-phosphate protein. Also acts on 5-hydroxy-L-lysine.
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History |
EC 4.1.1.18 created 1961
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Pathway |
ec00960 | Tropane, piperidine and pyridine alkaloid biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
ec01120 | Microbial metabolism in diverse environments |
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Orthology |
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Genes |
ECO: | b0186(ldcC) b4131(cadA) |
ECJ: | JW0181(ldcC) JW4092(cadA) |
ECD: | ECDH10B_0166(ldcC) ECDH10B_4324(cadA) |
EBW: | BWG_0178(ldcC) BWG_3845(cadA) |
ECOK: | ECMDS42_0173(ldcC) ECMDS42_3571(cadA) |
ECOC: | C3026_00855 C3026_22330 |
ECE: | Z0198(ldcC) Z5734(cadA) |
ECS: | ECs_0188(cadA_1) ECs_5113(cadA) |
ECF: | ECH74115_0196(ldcC1) ECH74115_5647(ldcC2) |
ETW: | ECSP_0185(ldcC) ECSP_5231(cadA) |
ELX: | CDCO157_0186 CDCO157_4798 |
EOJ: | ECO26_0188(ldcC) ECO26_5243(cadA) |
EOH: | ECO103_0184(ldcC) ECO103_4883(cadA) |
ECOO: | ECRM13514_0194(ldcC) ECRM13514_5348(cadA) |
ECOH: | ECRM13516_0196(ldcC) ECRM13516_5016(cadA) |
ECK: | EC55989_0180(ldcC) EC55989_4624(cadA) |
ECG: | E2348C_0191(ldcC) E2348C_4458(cadA) |
EOK: | G2583_0189(ldcC) G2583_4958(cadA) |
ELR: | ECO55CA74_00910 ECO55CA74_23770 |
ECW: | EcE24377A_0190(ldcC) EcE24377A_4686 |
EUN: | UMNK88_191 UMNK88_4998 |
ECP: | ECP_0194 ECP_0327 ECP_4375 |
ENA: | ECNA114_0176(ldcC) ECNA114_4317(cadA) |
ECOS: | EC958_0332(ldcC) EC958_4620(cadA) |
ECV: | APECO1_1801(ldcC) APECO1_2322(cadA) |
ECOA: | APECO78_01590 APECO78_04360 |
ECX: | EcHS_A0188(ldcC1) EcHS_A4372(ldcC2) |
ECM: | EcSMS35_0197(ldcC1) EcSMS35_4600(ldcC2) |
ECR: | ECIAI1_0186(ldcC) ECIAI1_4364(cadA) |
ECQ: | ECED1_0192(ldcC) ECED1_4867(cadA) |
EUM: | ECUMN_0183(ldcC) ECUMN_4665(cadA) |
ECT: | ECIAI39_0189(ldcC) ECIAI39_4560(cadA) |
EOC: | CE10_0188(ldcC) CE10_4850(cadA) |
EBR: | ECB_00184(ldcC) ECB_04002(cadA) |
ECOB: | C3029_02345 C3029_04700 |
EBL: | ECD_00184(ldcC) ECD_04002(cadA) |
EBE: | B21_00183(ldcC) B21_03964(cadA) |
ECI: | UTI89_C0201(ldcC) UTI89_C4728(cadA) |
ECZ: | ECS88_0197(ldcC) ECS88_4635(cadA) |
ECC: | c0224(ldcC) c5140(cadA) |
ELO: | EC042_0184(ldcC) EC042_4497(cadA) |
ELN: | NRG857_00950 NRG857_20725 |
ECL: | EcolC_3474 EcolC_3896 |
EKO: | EKO11_3732 EKO11_4187 |
EKF: | KO11_00900(ldcC) KO11_01675(cadA) |
EAB: | ECABU_c01990(ldcC) ECABU_c46850(cadA) |
EDH: | EcDH1_3417 EcDH1_3860 |
EDJ: | ECDH1ME8569_0179(ldcC) ECDH1ME8569_3991(cadA) |
ELU: | UM146_20895 UM146_23735 |
ELW: | ECW_m0182(ldcC) ECW_m4492(cadA) |
ELL: | WFL_00900(ldcC) WFL_21855(cadA) |
ELC: | i14_0206(ldcC) i14_4725(cadA) |
ELD: | i02_0206(ldcC) i02_4725(cadA) |
ELP: | P12B_c0174(ldcC) P12B_c4231(cadA) |
ELF: | LF82_0254(cadA) LF82_1172(ldcC) |
ECOL: | LY180_00900 LY180_21700 |
ECOI: | ECOPMV1_00192(ldcC) ECOPMV1_04591(cadA) |
ECOJ: | P423_00990 P423_23025 |
EFE: | EFER_0209(ldcC) EFER_1900(cadA) |
EAL: | EAKF1_ch2295c(ldcC2) |
STY: | STY0259(ldcC) STY2806(cadA) |
STT: | t0236(ldcC) t0297(cadA) |
SEX: | STBHUCCB_2580 STBHUCCB_3190 |
SENT: | TY21A_01215 TY21A_01510 |
STM: | STM0234(ldcC) STM2559(cadA) |
SEO: | STM14_0276(ldcC) STM14_3138(cadA) |
SEV: | STMMW_02401 STMMW_25761 |
SEY: | SL1344_0235(ldcC) SL1344_2521(cadA) |
SEM: | STMDT12_C02350 STMDT12_C25790 |
SEJ: | STMUK_0236(ldcC) STMUK_2591(cadA) |
SEB: | STM474_0243(ldcC) STM474_2664(cadA) |
SEF: | UMN798_0255(ldcC) UMN798_2763(cadA) |
SETU: | STU288_01180 STU288_09155 |
SETC: | CFSAN001921_03975 CFSAN001921_16230 |
SENR: | STMDT2_02361(ldcC) STMDT2_25201(cadA) |
SEND: | DT104_02391(ldcC) DT104_26111(cadA) |
SENI: | CY43_01175 CY43_13655 |
SEEN: | SE451236_07190 SE451236_19020 |
SPT: | SPA0241(ldcC) SPA0307(cadA) |
SPQ: | SPAB_00299 SPAB_00369 |
SEI: | SPC_0250(ldcC) SPC_1091(cadA) |
SEC: | SCH_0234(ldcC) SCH_2554(cadA) |
SEH: | SeHA_C0272 SeHA_C2822 |
SENH: | CFSAN002069_07975 CFSAN002069_18970 |
SEEH: | SEEH1578_10290 SEEH1578_22120 |
SEE: | SNSL254_A0256 SNSL254_A2760 |
SENN: | SN31241_12290 SN31241_36690 |
SEW: | SeSA_A0261 SeSA_A2801 |
SEA: | SeAg_B0275 SeAg_B2718 |
SENS: | Q786_01230 Q786_12670 |
SED: | SeD_A0256(ldcC) SeD_A2935 |
SEG: | SG0238(ldcC) SG2596(cadA) |
SEL: | SPUL_0254(ldcC) SPUL_0315(cadA) |
SEGA: | SPUCDC_0254(ldcC) SPUCDC_0315(cadA) |
SET: | SEN0241(ldcC) SEN2539(cadA) |
SENA: | AU38_01195 AU38_12865 |
SENO: | AU37_01195 AU37_12875 |
SENV: | AU39_01195 AU39_12875 |
SENQ: | AU40_01360 AU40_14470 |
SENL: | IY59_01220 IY59_13215 |
SENJ: | CFSAN001992_09805 CFSAN001992_20740 |
SEEC: | CFSAN002050_07710 CFSAN002050_19745 |
SEEB: | SEEB0189_006755 SEEB0189_018135 |
SEEP: | I137_01135 I137_01445 |
SENB: | BN855_2500(ldcC) BN855_26490 |
SENE: | IA1_01260 IA1_12795 |
SENC: | SEET0819_08100 SEET0819_20250 |
SES: | SARI_00317 SARI_02768 |
SBG: | SBG_0225(ldcC) SBG_2334(cadA) |
SBV: | N643_01095 N643_11355 |
SALZ: | EOS98_06150 EOS98_18035 |
SBC: | SbBS512_E0179(ldcC1) |
SDZ: | Asd1617_00249 Asd1617_05863 |
SHQ: | A0259_02295 A0259_04775 |
KPN: | KPN_00199(ldcC) KPN_00500(cadA) |
KPU: | KP1_1043(ldcC) KP1_1410(cadA) |
KPM: | KPHS_09330 KPHS_13090 |
KPH: | KPNIH24_04670 KPNIH24_22225 |
KPZ: | KPNIH27_04470 KPNIH27_06100 |
KPV: | KPNIH29_04865 KPNIH29_06750 |
KPW: | KPNIH30_04895 KPNIH30_06760 |
KPY: | KPNIH31_03155 KPNIH31_06665 |
KPG: | KPNIH32_04900 KPNIH32_06865 |
KPC: | KPNIH10_04645 KPNIH10_06580 |
KPQ: | KPR0928_04655 KPR0928_06495 |
KPT: | VK055_2051(cadA) VK055_2366 |
KPO: | KPN2242_03445 KPN2242_05280 |
KPR: | KPR_1130(ldcC) KPR_4061 |
KPI: | D364_00960 D364_02570 |
KPA: | KPNJ1_04113 KPNJ1_04521 |
KPS: | KPNJ2_04136 KPNJ2_04473 |
KPX: | PMK1_02507(ldcC) PMK1_02826(cadA) |
KPB: | FH42_21840 FH42_23450 |
KPNU: | LI86_19725 LI86_21690 |
KPNK: | BN49_1542 BN49_4138(ldcC) |
KPE: | KPK_4092 KPK_4534(ldcC) |
KPK: | A593_15410 A593_16900 |
KVD: | KR75_12790 KR75_14335 |
KVQ: | SP68_19465 SP68_20990 |
KOY: | J415_24280 J415_26175 |
KOM: | HR38_10265 HR38_12020 |
KOK: | KONIH1_05265 KONIH1_07220 |
KOC: | AB185_28820 AB185_30910 |
KQU: | AVR78_09245 AVR78_11005 |
KQV: | B8P98_21020 B8P98_22610 |
KLL: | BJF97_05810 BJF97_07665 |
KLW: | DA718_21060 DA718_23200 |
KAR: | LGL98_18840(cadA) LGL98_20420 |
KGR: | JJJ10_20840(cadA) JJJ10_22795 |
KPAS: | LUW96_11735 LUW96_14055(cadA) |
KLC: | K7H21_20855(cadA) K7H21_22935 |
KLM: | BWI76_05300 BWI76_07195 |
REE: | electrica_03794(cadA) electrica_04147(ldcC) |
ROR: | RORB6_12665 RORB6_14180 |
RON: | TE10_06740 TE10_08330 |
RAO: | DSD31_19215 DSD31_20850 |
RTG: | NCTC13098_06062(ldcC) |
EBT: | EBL_c28010(cadA1) EBL_c31760(cadA2) |
CLAP: | NCTC11466_03741(ldcC) |
PGE: | LG71_07875 LG71_10805 |
ESC: | Entcl_1196 Entcl_3519 Entcl_3551 |
KLE: | AO703_04185 AO703_15850 |
KIE: | NCTC12125_02837(ldcC) |
KAS: | KATP_11200(cadA) KATP_36880 |
KLU: | K7B04_00485(ldcC) K7B04_23410(cadA) |
BUF: | D8682_09495 D8682_11040 |
BFT: | MNO13_18190(cadA) MNO13_19710 |
BSEL: | RHD99_18100(cadA) RHD99_19645 |
AHN: | NCTC12129_00982(ldcC) NCTC12129_00987(cadA) |
YRE: | HEC60_13890(cadA) HEC60_22070 |
PSHI: | SAMEA2665130_0737(cadA_1) SAMEA2665130_1220(cadA_2) SAMEA2665130_2471(cadA_4) |
PSGC: | G163CM_17020(cadA) G163CM_27130(ldcC) |
PVJ: | LMA04_04590(cadA) LMA04_08165 LMA04_18410(cadA) |
SUPE: | P0H77_05140(ldcC) P0H77_15930(cadA) |
TOE: | QMG90_05085(cadA) QMG90_17300(ldcC) |
EBU: | CUC76_08980 CUC76_10615 |
EBB: | F652_2458 F652_3828(cadB) |
SMAR: | SM39_3366(cadA) SM39_3371(ldcC) |
SMAC: | SMDB11_3155(cadA) SMDB11_3161(ldcC) |
SMW: | SMWW4_v1c38880 SMWW4_v1c38920 |
SLQ: | M495_19635 M495_19665 |
SERF: | L085_09230 L085_09250 |
SERS: | SERRSCBI_18820 SERRSCBI_18840 |
SFW: | WN53_01640 WN53_01660 |
SFG: | AV650_24400 AV650_24420 |
SQU: | E4343_21565 E4343_21595 |
SFJ: | SAMEA4384070_3887(ldcC) |
SOF: | NCTC11214_02873(ldcC_2) NCTC11214_02880(cadA) |
SSUR: | ATE40_016110 ATE40_016130 |
SURI: | J0X03_04535 J0X03_04555(cadA) |
SNEM: | NLX84_19575(cadA) NLX84_19595 |
SNEV: | OI978_12535 OI978_12555(cadA) |
SGRI: | SGBXF1_03876(cadA) SGBXF1_03883(ldcC) |
SSAR: | SSARUM_003751(cadA) SSARUM_003755 |
PALH: | B1H58_02985 B1H58_15020 |
EIC: | NT01EI_0291 NT01EI_0859 NT01EI_3413 |
ETD: | ETAF_0246 ETAF_0700 ETAF_2734 |
ETE: | ETEE_1240(ldcC) ETEE_2039(ldcC) ETEE_2518(ldcC) |
ETR: | ETAE_0284(cadA1) ETAE_0757(cadA2) ETAE_3006(cadA3) |
ETC: | ETAC_01205 ETAC_03665 ETAC_14470 |
EDW: | QY76_05325 QY76_16540 |
EDL: | AAZ33_01275 AAZ33_03585 AAZ33_15915 |
EHO: | A9798_12765 A9798_15210 |
HAV: | AT03_02990 AT03_17370 |
HPAR: | AL518_02475 AL518_09050 |
OPO: | DSM2777_07875 DSM2777_23350 |
ADP: | NCTC12871_01111(cadA) |
VPL: | SA104470976_02458(cadA) |
LCJ: | NCTC11976_02922(cadA) |
AEL: | NCTC12917_03192(cadA) |
ECOR: | SAMEA4412678_1910(cadA) |
PPIO: | CE91St28_08010(cadA) |
» show all
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Reference |
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Authors |
Gale EF, Epps HM. |
Title |
Studies on bacterial amino-acid decarboxylases: 1. l(+)-lysine decarboxylase. |
Journal |
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Reference |
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Authors |
Soda K, Moriguchi M. |
Title |
Crystalline lysine decarboxylase. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.18 |
ExPASy - ENZYME nomenclature database: | 4.1.1.18 |
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LinkDB |
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