Entry |
|
Name |
diphosphomevalonate decarboxylase;
pyrophosphomevalonate decarboxylase;
mevalonate-5-pyrophosphate decarboxylase;
pyrophosphomevalonic acid decarboxylase;
5-pyrophosphomevalonate decarboxylase;
mevalonate 5-diphosphate decarboxylase;
ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)
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Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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Sysname |
ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)
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Reaction(IUBMB) |
ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 [RN: R01121]
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Reaction(KEGG) |
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Substrate |
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Product |
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History |
EC 4.1.1.33 created 1961
|
Pathway |
ec00900 | Terpenoid backbone biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K01597 | diphosphomevalonate decarboxylase |
|
Genes |
AJM: | 119038246 119047040(MVD) |
RKG: | 130086887(mvda) 130091188 |
CVG: | 107084103(mvd) 107098817 |
SASA: | 100195467(erg19) 106562275 |
STRU: | 115167177 115203155 |
OTW: | 112249244 112263756(mvda) |
OMY: | 110506596 110526469(mvda) |
SALP: | 111969439 111975040 |
CCLU: | 121548253 121558001 |
PSPA: | 121296376(mvda) 121326140 |
ARUT: | 117424473(mvda) 117425473 |
SCLV: | 120341830 120341998 |
LPIC: | 129254022 129254026 |
DSI: | Dsimw501_GD29521(Dsim_GD29521) |
RZE: | 108373758 108379997 108380864 |
AALB: | 109427742 109431404 |
CPII: | 120418093 120419900 |
DPL: | KGM_204656 KGM_204657 |
API: | 100158798(Mvd) 100160652 |
SGRE: | 126267281 126330063 |
CEL: | CELE_Y48B6A.13(Y48B6A.13) |
ATH: | AT2G38700(MVD1) AT3G54250 |
CSAT: | 104712004 104781291 104782317 104785607 104791697 |
EUS: | EUTSA_v10010411mg EUTSA_v10016888mg EUTSA_v10023484mg |
BNA: | 106411721 106413053 106431384 106431385 |
RSZ: | 108848804 108855303 108856214 |
MINC: | 123193683 123205993 123230346 |
HSYR: | 120123436 120161786 |
LANG: | 109336098 109346304 109354374 |
QSA: | O6P43_004894 O6P43_008739 |
PAVI: | 110769657 110773627 |
PDUL: | 117617229 117617230 |
MSYL: | 126591769 126629743 |
CMAX: | 111467606 111479145 |
CMOS: | 111449432 111458820 |
CPEP: | 111779924 111801410 |
MESC: | 110618417 110625089 |
PALZ: | 118045200 118060072 |
JRE: | 108985489 109002152 109009861 |
CILL: | 122292484 122294806 |
CAVE: | 132163851 132167176 132192151 |
SLY: | 100134900(MDC) 101254587 |
SPEN: | 107004563 107015872 |
SSTN: | 125844311 125856614 |
SDUL: | 129878779 129900015 |
NTA: | 107759723 107763449 107811776 107817230 |
OEU: | 111381017 111405372 111408343 |
SSPL: | 121741654 121744706 121773930 121796112 |
CCAV: | 112509626 112512507 |
CSIN: | 114261339 114319126 |
AEW: | 130752735 130760723 130764428 |
PSOM: | 113311043 113323021 |
TDC: | 119270674 119282643 119303569 119312228 |
TAES: | 123063615 123066929 123080934 123090324 123105429 123113703 123123228 |
TUA: | 125508570 125510973 125523663 125546284 |
MFLO: | 136464705 136464720 136464722 136467909 136478483 |
SITA: | 101783413 101785083 |
PVIR: | 120645007 120657479 120687548 120700118 |
PHAI: | 112878948 112884070 112886355 |
ZOF: | 121978605 122002327 122006586 |
SMO: | SELMODRAFT_135101 SELMODRAFT_268244 |
CGR: | 2886751(GVI51_C03421) |
NCS: | NCAS_0A05510(NCAS0A05510) |
NDI: | NDAI_0K02340(NDAI0K02340) |
TPF: | TPHA_0M01990(TPHA0M01990) |
TBL: | TBLA_0F04250(TBLA0F04250) |
TDL: | TDEL_0A07770(TDEL0A07770) |
KAF: | KAFR_0C04730(KAFR0C04730) |
KNG: | KNAG_0D00260(KNAG0D00260) |
LBG: | 92208159(LODBEIA_P29630) |
CAL: | CAALFM_C100070WA(MVD) |
YLI: | 2907970(YALI2_F00110g) |
NTE: | NEUTE1DRAFT117918(NEUTE1DRAFT_117918) |
SMP: | 10808883(SMAC4_03607) |
TATV: | 25785607(TrAtP1_010408) |
TASP: | 36613804(TrAFT101_010859) |
PLJ: | 90643241(PLICBS_007534) |
BFU: | BCIN_04g01890(Bcmvd1) |
CIM: | CIMG_11269(CIMG04156) |
PTRR: | 6342332(PtrM4_091620) |
ZTR: | MYCGRDRAFT_77157(MVD1) |
CDEP: | 91088008(L203_103798) |
KMG: | 30166254(I203_102323) |
KNE: | 92179960(IAR55_002702) |
CCAC: | CcaHIS019_0100420(MVD1) |
LBC: | LACBIDRAFT_190457 LACBIDRAFT_228351 |
ABP: | AGABI1DRAFT116646(AGABI1DRAFT_116646) |
ABV: | AGABI2DRAFT196085(AGABI2DRAFT_196085) |
SCM: | SCHCO_02691077(SCHCODRAFT_02691077) |
PTI: | PHATRDRAFT_bd1325(MPDC) |
EHX: | EMIHUDRAFT_445262(MVD1) |
TBR: | Tb10.05.0010 Tb10.61.2745 |
TBG: | TbgDal_X16420 TbgDal_X17290 |
TCR: | 507993.330 511281.40 |
LMAT: | 92516570(LSCM1_06646) |
LOI: | 92362844(LSCM4_07004) |
CBS: | COXBURSA331_A0720(mvaD_idi) |
LAS: | CLIBASIA_04590(mvaD) |
SAX: | USA300HOU_0584(mvaD) |
SUQ: | HMPREF0772_12597(mvaD) |
SUX: | SAEMRSA15_05190(mvaD) |
SUF: | SARLGA251_05260(mvaD) |
SAUT: | SAI1T1_2004550(mvaD) |
SAUJ: | SAI2T2_1004570(mvaD) |
SAUK: | SAI3T3_1004560(mvaD) |
SAUQ: | SAI4T8_1004550(mvaD) |
SAUV: | SAI7S6_1004560(mvaD) |
SAUW: | SAI5S5_1004520(mvaD) |
SAUX: | SAI6T6_1004530(mvaD) |
SAUY: | SAI8T7_1004560(mvaD) |
SPIC: | SAMEA4384060_2277(mvaD) |
SSIM: | SAMEA4384339_0539(mvaD) |
SPYM: | M1GAS476_0742(mvaD) |
SPH: | MGAS10270_Spy0741(mvaD) |
SPI: | MGAS10750_Spy0775(mvaD) |
SPJ: | MGAS2096_Spy0754(mvaD) |
SPK: | MGAS9429_Spy0738(mvaD) |
STG: | MGAS15252_0708(mvaD) |
STZ: | SPYALAB49_000709(mvaD) |
SNV: | SPNINV200_03440(mvaD) |
SNC: | HMPREF0837_10680(mvaD) |
SPNG: | HMPREF1038_00433(mvaD) |
SPNE: | SPN034156_14350(mvaD) |
SPNU: | SPN034183_03850(mvaD) |
SPNM: | SPN994038_03730(mvaD) |
SPNO: | SPN994039_03740(mvaD) |
SGG: | SGGBAA2069_c12560(mvaD) |
SCP: | HMPREF0833_11233(mvaD) |
SVB: | NCTC12167_00591(mvaD) |
SFER: | NCTC12278_01040(mvaD) |
SCAI: | NCTC12191_01812(mvaD) |
SPSU: | NCTC13786_02076(mvaD) |
SPOC: | NCTC10925_01061(mvaD) |
SAUP: | NCTC3168_01006(mvaD) |
SURN: | NCTC13766_00973(mvaD) |
SVF: | NCTC3166_01742(mvaD) |
SMIE: | NCTC11169_00162(mvaD) |
LPW: | LpgJCM5343_09150(mvaD) |
LRU: | HMPREF0538_22183(mvaD) |
LHIL: | G8J22_01432(thrB_1) |
LHO: | LOOC260_110680(mvaD) |
EFU: | HMPREF0351_10224(mvaD) |
AUR: | HMPREF9243_0782(mvaD) |
AMIT: | DBT49_0006495(mvaD) |
JDA: | BW727_101265(thrB_2) |
NBR: | O3I_007935 O3I_033240 |
NAH: | F5544_04360(mvaD) F5544_24680(mvaD) |
SQZ: | FQU76_00345(mvaD) FQU76_32125(mvaD) FQU76_33395(mvaD) |
SXT: | KPP03845_300050(thrB) |
PPC: | HMPREF9154_0775(mvaD) |
MSAG: | GCM10017556_12040(mvd) |
ATIM: | CYJ17_0004960(mvaD) |
ANE: | ATCC27039_12790(mvd) |
ACAP: | MANAM107_01670(mvd) |
GVG: | HMPREF0421_21152(mvaD) |
GVA: | HMPREF0424_0313(mvaD) |
GVH: | HMPREF9231_0384(mvaD) |
BCOI: | bcCo53_000686(mvaD) |
BPUR: | bpuSUM_000692(mvaD) |
BVW: | bvRMA01_000690(mvaD) |
FOK: | KK2020170_04150(mvaD) |
SPON: | HME9304_01049(mvaD) |
FBU: | UJ101_01463(MVD|mvaD) |
TMG: | US01_C0001G0070(mvaD) |
MIB: | UY43_C0001G1160(mvaD) |
» show all
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Reference |
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Authors |
BLOCH K, CHAYKIN S, PHILLIPS AH, DE WAARD A. |
Title |
Mevalonic acid pyrophosphate and isopentenylpyrophosphate. |
Journal |
J Biol Chem 234:2595-604 (1959) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.33 |
ExPASy - ENZYME nomenclature database: | 4.1.1.33 |
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LinkDB |
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