KEGG   ORTHOLOGY: K01617
Entry
K01617                      KO                                     
Symbol
dmpH, xylI, nahK
Name
2-oxo-3-hexenedioate decarboxylase [EC:4.1.1.77]
Pathway
map00362  Benzoate degradation
map00621  Dioxin degradation
map00622  Xylene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K01617  dmpH, xylI, nahK; 2-oxo-3-hexenedioate decarboxylase
   00622 Xylene degradation
    K01617  dmpH, xylI, nahK; 2-oxo-3-hexenedioate decarboxylase
   00621 Dioxin degradation
    K01617  dmpH, xylI, nahK; 2-oxo-3-hexenedioate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.77  2-oxo-3-hexenedioate decarboxylase
     K01617  dmpH, xylI, nahK; 2-oxo-3-hexenedioate decarboxylase
Other DBs
RN: R02602 R05374
GO: 0047437
Genes
PGE: LG71_12235
SLQ: M495_05200
PSD: DSC_09165
RTH: LRK53_10280(dmpH)
RBD: ALSL_0876
PPSE: BN5_3617(nahK)
PFUW: KF707C_15590(bzaI) KF707C_16040(SalI)
PCQ: PcP3B5_23510(amnE)
PPW: PputW619_2010
PPI: ND083(nahK)
PKC: PKB_3258(amne1) PKB_3606(amne3)
PSOS: POS17_2260
PSET: THL1_489
PSEP: C4K39_5744
PTAE: NCTC10697_02308(amnE)
AVN: Avin_08680(xylI) Avin_30600(lapH)
AVL: AvCA_08680(xylI) AvCA_30600(lapH)
AVD: AvCA6_08680(xylI) AvCA6_30600(lapH)
ACX: Achr_32760(xylI)
HPEG: EAO82_00540(dmpH) EAO82_09440(dmpH)
HAES: LO767_17685(dmpH)
MARJ: MARI_05470(tesE)
SWD: Swoo_1406
SALH: HMF8227_02737(hpaH)
AFUS: EYZ66_02600(dmpH)
CYQ: Q91_0511
CYY: CPC19_10500(dmpH)
BLEP: AL038_01285(dmpH)
THIS: HZT40_10620(dmpH)
APAC: S7S_07005
MGEO: CFI10_00440(dmpH) CFI10_04975(dmpH)
MSEC: LN244_11315(dmpH)
NCU: F0U83_03060(dmpH)
NIK: F5I99_10090(dmpH) F5I99_10505(dmpH)
ASIM: FE240_03475(dmpH)
SINI: GT972_13735(dmpH)
TBN: TBH_C0931
NZO: SAMEA4504057_0445(mhpD)
NCI: NCTC10296_00916(xylJ_2)
NWD: H3L96_04770(dmpH)
NDU: LVJ88_00585(dmpH)
PTES: JQU52_04855(dmpH)
USU: LVJ78_03655(dmpH)
CHRO: CXB49_03845(dmpH)
RSO: RSp0892
RSE: F504_4325
RPI: Rpic_4619
RIN: ACS15_4682(amnE)
REH: H16_B0549(h16_B0549)
CNC: CNE_2c04950(dmpH) CNE_BB1p11980(xylI) CNE_BB1p13270(dmpH)
RME: Rmet_1318(dmpH) Rmet_5210(amnE)
BCJ: BCAM2123
BCEN: DM39_4831(dmpH)
BCEO: I35_6005
BMUL: NP80_3871(amnE)
BCT: GEM_5400
BCED: DM42_4990(dmpH)
BCON: NL30_24585
BTEI: WS51_00575
BPSL: WS57_12150
BANN: JFN94_19140(dmpH)
BXE: Bxe_A1150(amnE)
BXB: DR64_3309(amnE)
BFN: OI25_254(amnE)
PARB: CJU94_37885(dmpH) CJU94_38130(dmpH)
PPNO: DA70_10725
PPNM: LV28_20330
PPUL: RO07_14670
PSPU: NA29_22520
PAPI: SG18_14500
CABA: SBC2_61030(amnE)
LIMN: HKT17_03835(dmpH)
BHZ: ACR54_00827(amnE)
AMIM: MIM_c06230
AJS: Ajs_0225
AMON: H9L24_14170(dmpH)
VEI: Veis_2784
VBO: CKY39_28490(dmpH)
COF: FOZ74_08325(dmpH)
HPSE: HPF_01820(tesE2) HPF_01865(tesE3)
HYN: F9K07_02755(dmpH)
SIMP: C6571_13630(dmpH)
MELA: C6568_07845(dmpH)
MJE: LVC68_01035(dmpH)
STHM: IS481_10535(dmpH)
METP: C1M51_06455(dmpH) C1M51_15395(dmpH)
JAG: GJA_235(dmpH)
LCH: Lcho_3342
SNN: EWH46_19320(dmpH)
IDC: LRM40_19575(dmpH)
DEY: HYN24_14125(dmpH) HYN24_14195(dmpH)
FLE: KI610_08580(dmpH) KI610_13440(dmpH) KI610_15445(dmpH)
AZO: azo1854(lapH) azo2430(nahK)
AZD: CDA09_10340(dmpH) CDA09_10445(dmpH)
AZR: CJ010_12255(dmpH) CJ010_15200(dmpH)
THK: CCZ27_10765(dmpH) CCZ27_16280(dmpH)
AZQ: G3580_00540(dmpH) G3580_08285(dmpH)
ACIB: ACBT_0258(dmpH)
AFC: AFAEC_1843(dmpH)
AAQI: AAQM_0983(dmpH)
ACLO: ACLO_a0138(dmpH)
ADZ: ADFLV_2550(dmpH)
ALK: ALEK_0384(dmpH)
AANA: AANAER_1261(dmpH)
ARC: ABLL_2441
MXA: MXAN_0925
CCX: COCOR_00872(dmpH)
ARA: Arad_7266
RLE: pRL120704
MET: M446_1050
MSL: Msil_1480
MTUN: MTUNDRAET4_3891(amnE)
TEC: AKL02_008260(dmpH)
NAR: Saro_3851
SMAZ: LH19_00750
SGI: SGRAN_3551(amnE)
SPKC: KC8_11575
SJP: SJA_C1-11880(hpaH_xylI)
SINB: SIDU_08325
SHYD: CJD35_06495(dmpH)
KSC: CD178_01495(amnE)
MAGQ: MGMAQ_0652
HTL: HPTL_0045
BLI: BL03907
BLD: BLi03993(xylI)
BSON: S101395_00392(dmpH)
BCA: BCE_2158
BCX: BCA_2156
BCF: bcf_10220
BCER: BCK_24215
BTL: BALH_1845
BMYC: DJ92_4639
BACO: OXB_2505
BGY: BGLY_4397
BFD: NCTC4823_00794(xylJ)
BMQ: BMQ_3586
BMD: BMD_3571
BMEG: BG04_460
GTN: GTNG_3150(nbaG)
PCAL: BV455_00226(tesE_1)
PASA: BAOM_0499
ASOC: CB4_02453(amnF)
AAC: Aaci_1618
AAD: TC41_1514
BTS: Btus_0970
SAY: TPY_0643
MIT: OCO_14790
MIA: OCU_15230
MMAN: MMAN_42240
MJL: Mjls_4208
MHEV: MHEL_01620
CEE: CENDO_03490(amnE)
COK: COCCU_04385(amnE)
NFA: NFA_30430
NFR: ERS450000_00296(xylJ_1) ERS450000_01021(xylJ_2)
REY: O5Y_02265
REQ: REQ_05050(amnD)
RRT: 4535765_01257(amnE)
GBR: Gbro_0225
SBH: SBI_01536
SGE: DWG14_08258(amnE)
NCA: Noca_2055
TCU: Tcur_0537
SRO: Sros_9112
NML: Namu_0794
AMD: AMED_8622
AMN: RAM_44250
AMM: AMES_8491
AMZ: B737_8492
AOI: AORI_7401
AORI: SD37_03455
ALO: CRK56594
SAQ: Sare_3899
MIL: ML5_3358
IIS: EYM_02850
AG: CAA43228(dmpH)
 » show all
Reference
PMID:1732207
  Authors
Shingler V, Powlowski J, Marklund U
  Title
Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600.
  Journal
J Bacteriol 174:711-24 (1992)
DOI:10.1128/JB.174.3.711-724.1992
  Sequence
LinkDB

KEGG   ENZYME: 4.1.1.77
Entry
EC 4.1.1.77                 Enzyme                                 
Name
2-oxo-3-hexenedioate decarboxylase;
4-oxalocrotonate carboxy-lyase (misleading);
4-oxalocrotonate decarboxylase (misleading);
cnbF (gene name);
praD (gene name);
amnE (gene name);
nbaG (gene name);
xylI (gene name)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
(3E)-2-oxohex-3-enedioate carboxy-lyase (2-oxopent-4-enoate-forming)
Reaction(IUBMB)
(3E)-2-oxohex-3-enedioate = 2-oxopent-4-enoate + CO2 [RN:R02602]
Reaction(KEGG)
R02602;
(other) R05374
Substrate
(3E)-2-oxohex-3-enedioate
Product
2-oxopent-4-enoate [CPD:C00596];
CO2 [CPD:C00011]
Comment
Involved in the meta-cleavage pathway for the degradation of phenols, modified phenols and catechols. The enzyme has been reported to accept multiple tautomeric forms [1-4]. However, careful analysis of the stability of the different tautomers, as well as characterization of the enzyme that produces its substrate, EC 5.3.2.6, 2-hydroxymuconate tautomerase, showed that the actual substrate for the enzyme is (3E)-2-oxohex-3-enedioate [4].
History
EC 4.1.1.77 created 1999, modified 2011, modified 2012
Pathway
ec00362  Benzoate degradation
ec00621  Dioxin degradation
ec00622  Xylene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01617  2-oxo-3-hexenedioate decarboxylase
Genes
PGELG71_12235
SLQM495_05200
PSDDSC_09165
RTHLRK53_10280(dmpH)
RBDALSL_0876
PPSEBN5_3617(nahK)
PFUWKF707C_15590(bzaI) KF707C_16040(SalI)
PCQPcP3B5_23510(amnE)
PPWPputW619_2010
PPIND083(nahK)
PPJRK21_04234
PVRPverR02_14695
PSCA458_06505
PSTUUIB01_22755
PBMCL52_14725
PKCPKB_3258(amne1) PKB_3606(amne3)
PALKPSAKL28_05950
PSOSPOS17_2260
PFKPFAS1_28760
PSETTHL1_489
PALLUYA_06735 UYA_06965 UYA_20140
PSEPC4K39_5744
PTRTHU722_0015015
PPHABVH74_06170
PTAENCTC10697_02308(amnE)
AVNAvin_08680(xylI) Avin_30600(lapH)
AVLAvCA_08680(xylI) AvCA_30600(lapH)
AVDAvCA6_08680(xylI) AvCA6_30600(lapH)
ACXAchr_32760(xylI)
HPEGEAO82_00540(dmpH) EAO82_09440(dmpH)
HAESLO767_17685(dmpH)
MADHP15_1116 HP15_4037
MSRAU15_09345 AU15_21065 AU15_22100
MLQASQ50_09200
MSQBKP64_13835
MARJMARI_05470(tesE)
SWDSwoo_1406
SEURFM038_016465
LALAT746_01265
SALHHMF8227_02737(hpaH)
KIMG3T16_05370
AFUSEYZ66_02600(dmpH)
CYQQ91_0511
CZACYCME_2100
CYYCPC19_10500(dmpH)
BLEPAL038_01285(dmpH)
THISHZT40_10620(dmpH)
HCSFF32_08365
HALKCUU95_03815
HVNEI420_02115
HTXEKK97_09975
APACS7S_07005
MGEOCFI10_00440(dmpH) CFI10_04975(dmpH)
MSECLN244_11315(dmpH)
NCUF0U83_03060(dmpH)
NJPNEJAP_0674
NIKF5I99_10090(dmpH) F5I99_10505(dmpH)
AJPAMJAP_2996
ASIMFE240_03475(dmpH)
ZDFAN401_14610
SINIGT972_13735(dmpH)
GBIPG2T_09680
TBNTBH_C0931
NZOSAMEA4504057_0445(mhpD)
NCINCTC10296_00916(xylJ_2)
NWDH3L96_04770(dmpH)
NDULVJ88_00585(dmpH)
VFFVITFI_CDS1371
PTESJQU52_04855(dmpH)
USULVJ78_03655(dmpH)
CHROCXB49_03845(dmpH)
CRZD1345_11510
CHAECH06BL_23590
AQLBXU06_16890
AQSDKK66_07205
RSORSp0892
RSMCMR15_mp10876
RSEF504_4325
RPIRpic_4619
RPFRpic12D_3543
RPJN234_08155 N234_12210
RINACS15_4682(amnE)
RPUCDC45_22075
REHH16_B0549(h16_B0549)
CNCCNE_2c04950(dmpH) CNE_BB1p11980(xylI) CNE_BB1p13270(dmpH)
REUReut_B5500 Reut_B5692
RMERmet_1318(dmpH) Rmet_5210(amnE)
CBWRR42_m1052 RR42_s2483
CCUPBKK81_23320 BKK81_27095
CUPBKK80_29225 BKK80_32995
CUUBKK79_23880 BKK79_35175
COXE0W60_03750 E0W60_07780(dmpH)
BVIBcep1808_7606
BURBcep18194_B2958 Bcep18194_C7643
BCJBCAM2123
BCENDM39_4831(dmpH)
BCEOI35_6005
BMULNP80_3871(amnE)
BCTGEM_5400
BCEDDM42_4990(dmpH)
BCONNL30_24585
BDFWI26_16000
BTEIWS51_00575
BPSLWS57_12150
BSTLBBJ41_10525 BBJ41_33955
BANNJFN94_19140(dmpH)
BUGBC1001_0834
BUQAC233_11180
BXEBxe_A1150(amnE)
BXBDR64_3309(amnE)
BPXBUPH_05359
BPYBphyt_1469
BFNOI25_254(amnE)
PARBCJU94_37885(dmpH) CJU94_38130(dmpH)
PTERC2L65_38850
BRHRBRH_00201
PPKU875_01885 U875_18215
PPNODA70_10725
PPNMLV28_20330
PRBX636_07585 X636_15900
PPULRO07_14670
PSPUNA29_22520
PAPISG18_14500
PVEUC34_05805
POXMB84_10225
PFGAB870_16830
PNRAT302_01280
PANDDRB87_05210
PFIBPI93_022455
CABASBC2_61030(amnE)
LIMNHKT17_03835(dmpH)
BHZACR54_00827(amnE)
BOJCBF45_01485 CBF45_04495 CBF45_06950 CBF45_16995
PUDG9Q38_15000
AKATKWG_04045
AMIMMIM_c06230
CDNBN940_01171 BN940_04311
PIGEGT29_19205
KGYEHF36_01670(dmpH) EHF36_04880(dmpH) EHF36_16935
POLBpro_1513 Bpro_5137
AJSAjs_0225
ACIDCBP33_01120
ACIPCBP36_01215
ACINCBP34_01125
ACISCBP35_17735
AMONH9L24_14170(dmpH)
VEIVeis_2784
VPDVAPA_1c22830
VBOCKY39_28490(dmpH)
CTTCtCNB1_3146
COFFOZ74_08325(dmpH)
ADNAlide_0340
ADKAlide2_0285
HYLLPB072_18185
HPSEHPF_01820(tesE2) HPF_01865(tesE3)
HYNF9K07_02755(dmpH)
HTNKI616_01940 KI616_01960(dmpH)
DIHG7047_01665(dmpH) G7047_06945
DRGH9K76_11650(dmpH) H9K76_22950
SIMPC6571_13630(dmpH)
MELAC6568_07845(dmpH)
MJELVC68_01035(dmpH)
STHMIS481_10535(dmpH)
MPTMpe_A2272 Mpe_A3324
METPC1M51_06455(dmpH) C1M51_15395(dmpH)
JAGGJA_235(dmpH)
JAJEKL02_01820(dmpH) EKL02_15560
HEEhmeg3_19570
LCHLcho_3342
RDPRD2015_407
MIUABE85_21105
SNNEWH46_19320(dmpH)
IDCLRM40_19575(dmpH)
AIQAzoinq_09670
RBUPG1C_09715 PG1C_14085
DARDaro_2773 Daro_3781
DEYHYN24_14125(dmpH) HYN24_14195(dmpH)
FLEKI610_08580(dmpH) KI610_13440(dmpH) KI610_15445(dmpH)
AZOazo1854(lapH) azo2430(nahK)
AOAdqs_2007 dqs_2574
AZDCDA09_10340(dmpH) CDA09_10445(dmpH)
AZRCJ010_12255(dmpH) CJ010_15200(dmpH)
TMZTmz1t_3090
THUAC731_001825
THKCCZ27_10765(dmpH) CCZ27_16280(dmpH)
AZQG3580_00540(dmpH) G3580_08285(dmpH)
ACIBACBT_0258(dmpH)
AFCAFAEC_1843(dmpH)
AAQIAAQM_0983(dmpH)
ACLOACLO_a0138(dmpH)
ADZADFLV_2550(dmpH)
ALKALEK_0384(dmpH)
AANAAANAER_1261(dmpH)
ARCABLL_2441
MXAMXAN_0925
MSDMYSTI_00945
MYMA176_006054
MFBMFUL124B02_05300
CCXCOCOR_00872(dmpH)
MFULILAB_04080
MMASMYMAC_000948
SURSTAUR_2722
AGEAA314_01330
AVMJQX13_18930
PCAYFRD00_17510
ARAArad_7266
RLEpRL120704
BICLMTR13_06470
MRDMrad2831_4067
METM446_1050
MSLMsil_1480
MTUNMTUNDRAET4_3891(amnE)
DSALK1X15_13430
MAADAZF01_08270 AZF01_21095
MLUTJET14_11070
ACUTMRB58_02670
OCTFTO60_10555
CEHCEW89_11450
SUAMBOO69_22210
TECAKL02_008260(dmpH)
NARSaro_3851
NPPPP1Y_AT15722 PP1Y_AT31571
NPNJI59_24645
NOGGKE62_05080
SMAGAN936_00740
SMAZLH19_00750
STERAOA14_03895
SGISGRAN_3551(amnE)
SPHOC3E99_12570
SWISwit_0912 Swit_3521
SPHDHY78_06675 HY78_22125
SPKCKC8_11575
SJPSJA_C1-11880(hpaH_xylI)
SINBSIDU_08325
SYBTZ53_09015 TZ53_23460
SHYDCJD35_06495(dmpH)
SUFLFIL70_19000
SBARH5V43_20650 H5V43_22345
SPPHKFK14_16525
SPHYCHN51_06980
SPHJBSL82_10450
CNAAB433_18115
ERYCP97_03155 CP97_14235
KSCCD178_01495(amnE)
NCBC0V82_23405
MAGQMGMAQ_0652
BDQCIK05_11235
HTLHPTL_0045
BLIBL03907
BLDBLi03993(xylI)
BLHBaLi_c40070
BSONS101395_00392(dmpH)
BCABCE_2158
BCXBCA_2156
BCFbcf_10220
BCERBCK_24215
BCEFBcrFT9_01690
BTLBALH_1845
BMYCDJ92_4639
BTROFJR70_09215
BNTGSN03_10155
BACIB1NLA3E_08440 B1NLA3E_09300
GSTHW35_13045
BACOOXB_2505
BSMBSM4216_0950
BGYBGLY_4397
BACQDOE78_09235
BFDNCTC4823_00794(xylJ)
BDAFSZ17_11250
BHKB4U37_13930
BMQBMQ_3586
BMDBMD_3571
BMEGBG04_460
BPFBpOF4_12615
OCNCUC15_03685
GTNGTNG_3150(nbaG)
GYCGYMC61_2299
GYAGYMC52_1427
GCTGC56T3_2054
GMCGY4MC1_1597
GGHGHH_c14850
GJFM493_17910
GEJA0V43_04660
GZAIC807_03370
GTHGeoth_1680
PTLAOT13_14435
PCALBV455_00226(tesE_1)
ASEDIRT44_17615
LGYT479_19640
LYBC3943_22670
LYZDCE79_01760
LPAKGDS87_20225
VIGBKP57_09375
LAOAOX59_17255
FPNABE65_004750
FARABE41_004890
APAKAP3564_06555
BSJUP17_10530
PASABAOM_0499
RUEDT065_12670 DT065_13795 DT065_15120 DT065_15210
SALEEPH95_15045
NTMBTDUT50_14545
AIAAWH56_018055
BOUI5818_04805
HYIK2M58_09700 K2M58_09725
GAJMY490_08575
BBEBBR47_29790
BFMBP422_09725
BCHSJNE38_24125
PNPIJ22_00700 IJ22_32390 IJ22_48600
ANXACH33_11700
ASOCCB4_02453(amnF)
ATHEK3F53_07240
COHEAV92_02610
AACAaci_1618
AADTC41_1514
BTSBtus_0970
KYRCVV65_10340 CVV65_11285
EFFskT53_33780
SOBCSE16_14625
SPAEE2C16_04465 E2C16_12275
AUIAPT62_01025
AVSAWM76_09545
CARNFPV25_04350
SAYTPY_0643
SAPSulac_2996
MITOCO_14790
MIAOCU_15230
MMANMMAN_42240
MJLMjls_4208
MYVG155_08390 G155_08470
MGOAFA91_00030
MHOLK3U96_19110
MFTXA26_16790 XA26_16950
MLLB1R94_25050
MHEVMHEL_01620
MMATMMAGJ_45260 MMAGJ_45420
CHNA605_04755
CEECENDO_03490(amnE)
COKCOCCU_04385(amnE)
NFANFA_30430
NFRERS450000_00296(xylJ_1) ERS450000_01021(xylJ_2)
NNONONO_c62050
NTPCRH09_30230
NWLNWFMUON74_07310
RHARHA1_ro03880
RERRER_04710 RER_59340
REYO5Y_02265
REBXU06_02465
RQIC1M55_02650
ROPROP_37490 ROP_54170
REQREQ_05050(amnD)
RPYY013_12560
RBYCEJ39_00065
RAVAAT18_08105
RRZCS378_23120
RHQIM25_04200
RHODAOT96_13015
RRT4535765_01257(amnE)
RKOJWS14_41315
RGOKYT97_21980
GBRGbro_0225
GTABCM27_21915
GOCCXX93_11295
GOILK459_10160
DIZCT688_01890
TOYFO059_00305
SCBSCAB_15181
SSXSACTE_4113
SRCM271_50380
SBHSBI_01536
STRTA8713_24465
SVUB1H20_29090
SGEDWG14_08258(amnE)
SNKCP967_06830
SSUBCP968_28065
SPLACP981_35170
SCALI6J39_28940
SROIIAG44_01280
STRYEQG64_09025
KITCFP65_1237
YIALO772_34585
MVDAWU67_16690
AGYATC03_02580
PSAIC3B54_11904
SALDFVA74_00730
LTREVS81_03255
HEAHL652_17940
ARZAUT26_08860
ACITHPK19_02435
ICAIntca_1093
JTEASJ30_00110
JLIEXU32_15355
JMEEEW87_015420
PEIH9L10_13720
AUSIPK37_11690
RAINRai3103_12620
NCANoca_2055
NPIG7071_16490
TCUTcur_0537
ACTWF7P10_40030
AGRAAGRA3207_000779 AGRA3207_003642
SROSros_9112
NGNLCN96_28045
FRIFraEuI1c_1245
NMLNamu_0794
AMDAMED_8622
AMNRAM_44250
AMMAMES_8491
AMZB737_8492
AOIAORI_7401
AJAAJAP_01985
AMQAMETH_5437
AMYCCU254_17665 CU254_35760
AMYBBKN51_30410
AORISD37_03455
AACDLWP59_38180
PDXPsed_2523 Psed_4292
PBROHOP40_26620 HOP40_31750
ALOCRK56594
PMADBAY61_16755
STPStrop_3524
SAQSare_3899
MAUMicau_4937
MILML5_3358
MICBMicB006_3969
MTUACSH63_33405
MTEMGCE86_19380
MCABHXZ27_25040
VMAVAB18032_17780 VAB18032_28741
MCRAID554_21670 ID554_30890
PFLAPflav_027520
PSUUPsuf_068140
VERHUT12_13555 HUT12_26050
PRYPrubr_10590 Prubr_59260
CATICS0771_01260
NHYJQS43_06620
PVNA7sIIA15_04525
BSOLFSW04_07220
IISEYM_02850
 » show all
Reference
1  [PMID:1732207]
  Authors
Shingler V, Powlowski J, Marklund U
  Title
Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600.
  Journal
J Bacteriol 174:711-24 (1992)
DOI:10.1128/JB.174.3.711-724.1992
  Sequence
Reference
2  [PMID:9683650]
  Authors
Takenaka S, Murakami S, Shinke R, Aoki K
  Title
Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway.
  Journal
Arch Microbiol 170:132-7 (1998)
DOI:10.1007/s002030050624
Reference
3  [PMID:10651637]
  Authors
Stanley TM, Johnson WH Jr, Burks EA, Whitman CP, Hwang CC, Cook PF
  Title
Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase.
  Journal
Biochemistry 39:718-26 (2000)
DOI:10.1021/bi9918902
Reference
4  [PMID:17902707]
  Authors
Wang SC, Johnson WH Jr, Czerwinski RM, Stamps SL, Whitman CP
  Title
Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions.
  Journal
Biochemistry 46:11919-29 (2007)
DOI:10.1021/bi701231a
Reference
5  [PMID:19717587]
  Authors
Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E
  Title
Uncovering the protocatechuate 2,3-cleavage pathway genes.
  Journal
J Bacteriol 191:6758-68 (2009)
DOI:10.1128/JB.00840-09
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.77
IUBMB Enzyme Nomenclature: 4.1.1.77
ExPASy - ENZYME nomenclature database: 4.1.1.77
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.77
BRENDA, the Enzyme Database: 4.1.1.77
CAS: 37325-55-6
LinkDB

KEGG   REACTION: R05374
Entry
R05374                      Reaction                               
Name
2-Oxo-5-methyl-cis-muconate carboxy-lyase
Definition
2-Oxo-5-methyl-cis-muconate <=> 2-Hydroxy-cis-hex-2,4-dienoate + CO2
Equation
Comment
Ref.: 1. Jounal of bacteriology Vol.177 No5 1196-1201
Ref.:2. J Bacteriol 1989 ;171(11) :6251-6258
Reaction class
RC02672  C07479_C11354
Enzyme
Pathway
rn00622  Xylene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Orthology
K01617  2-oxo-3-hexenedioate decarboxylase [EC:4.1.1.77]
LinkDB

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