Entry
Name
4-hydroxy-2-oxovalerate aldolase;
4-hydroxy-2-ketovalerate aldolase;
HOA;
DmpG;
4-hydroxy-2-oxovalerate pyruvate-lyase;
4-hydroxy-2-oxopentanoate pyruvate-lyase;
BphI;
4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming)
Class
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
BRITE hierarchy
Sysname
(S)-4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming)
Reaction(IUBMB)
(S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate
Reaction(KEGG)
Substrate
(S)-4-hydroxy-2-oxopentanoate
Product
Comment
Requires Mn2+ for maximal activity [1]. The enzyme from the bacterium Pseudomonas putida is also stimulated by NADH [1]. In some bacterial species the enzyme forms a bifunctional complex with EC
1.2.1.10 , acetaldehyde dehydrogenase (acetylating). The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC
4.1.3.43 , 4-hydroxy-2-oxohexanoate aldolase [4,5].
History
EC 4.1.3.39 created 2006, modified 2011
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K01666 4-hydroxy 2-oxovalerate aldolase
K18365 4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase
Genes
ECOC : C3026_01735 C3026_24895
ECOO : ECRM13514_0494(mhpE)
ECOH : ECRM13516_0332(mhpE)
ECW : EcE24377A_0376(mhpE)
EDJ : ECDH1ME8569_0339(mhpE)
ELP : P12B_c0312(mhpE) P12B_c0370(mhpE)
REE : electrica_02140(mhpE)
PGE : LG71_09595 LG71_12220
PSGC : G163CM_06430(mhpE_1) G163CM_10090(mhpE_2)
SLQ : M495_05205 M495_15440
SERA : Ser39006_017380(dmpG)
XHO : A9255_04205 A9255_07220
LRI : NCTC12151_03194(mhpE)
VPL : SA104470976_02492(mhpE)
VIB : VspSTUT11_14740(mhpE)
PRE : PCA10_13840 PCA10_22760 PCA10_33740 PCA10_p0390(carE)
PFUW : KF707C_12190 KF707C_15580(bzaH) KF707C_16050(salH) KF707C_16230(bphX3)
PLAL : FXN65_06430(dmpG) FXN65_26400
PCQ : PcP3B5_23500(mhpE) PcP3B5_25720(dmpG)
PPW : PputW619_1984 PputW619_2007
PPX : T1E_4258(cmtG) T1E_4274(tobH)
PPUT : L483_06510 L483_14055
PMON : X969_10895 X969_10970
PMOT : X970_10550 X970_10625
PVR : PverR02_11585 PverR02_12290 PverR02_14390 PverR02_14710
PPUU : PputUW4_01662(mhpE)
PKC : PKB_1193 PKB_3256(amng1) PKB_3604(amng3) PKB_4237(nahM)
PPSY : AOC04_07825 AOC04_16965
PSIL : PMA3_11725 PMA3_18060
PKE : DLD99_14425(dmpG) DLD99_14495(dmpG) DLD99_14740(dmpG)
PPSH : G5J76_13480(dmpG) G5J76_17860(dmpG)
PSEP : C4K39_5453 C4K39_5743
PTRT : HU722_0015010(dmpG)
PTAE : NCTC10697_02055(bphI) NCTC10697_02309(dmpG)
PCAV : D3880_02365(dmpG) D3880_08165(dmpG) D3880_11800(dmpG) D3880_17515(dmpG)
PPHN : HU825_04960(dmpG) HU825_14765(dmpG)
PIZ : LAB08_R28800(dmpG) LAB08_R40950(dmpG)
PASI : LG197_17415(dmpG) LG197_17490(dmpG)
PKM : PZ739_11535(dmpG) PZ739_18240(dmpG)
PLAU : I0D68_06170(dmpG) I0D68_15115(dmpG)
PFOU : OZ911_06570 OZ911_14070(dmpG)
PSKP : KU43P_19460(mhpE_1) KU43P_25800(mhpE_2)
PALL : UYA_06730 UYA_06970 UYA_07050 UYA_20145
AVN : Avin_08740(xylK) Avin_15130(mphE) Avin_30570(lapG) Avin_42120
AVL : AvCA_08740(xylK) AvCA_15130(mphE) AvCA_30570(lapG) AvCA_42120
AVD : AvCA6_08740(xylK) AvCA6_15130(mphE) AvCA6_30570(lapG) AvCA6_42120
ACX : Achr_27750(mphE) Achr_32700(xylK)
HPEG : EAO82_00545(dmpG) EAO82_09435(dmpG)
PPHA : BVH74_06165 BVH74_11175 BVH74_16340 BVH74_17970
MSR : AU15_09340 AU15_21070
MLQ : ASQ50_04355 ASQ50_09205
MALL : PBN92_01680(dmpG) PBN92_14995
MSHE : MAALD49_03450(mhpE) MAALD49_03530(mhpE) MAALD49_03880(mhpE)
MANP : EHN06_02455(dmpG) EHN06_02800(dmpG)
ADV : DJ533_01780(dmpG) DJ533_16960(dmpG)
ATN : FM020_06350(dmpG) FM020_13980(dmpG)
ABOU : ACBO_15590(mhpE_1) ACBO_27740(mhpE_2)
ACIG : BS636_03595(dmpG) BS636_11020(dmpG)
PTN : PTRA_a0482(mhpE) PTRA_a2596(bphI)
AMAG : I533_16590 I533_16700
SALH : HMF8227_02732(bphI)
SPOI : IMCC21906_00395 IMCC21906_02714
ZAL : AZF00_03870 AZF00_11420 AZF00_17810
AFUS : EYZ66_02685(dmpG) EYZ66_12975(dmpG)
LLG : 44548918_00735(bphI)
LJR : NCTC11533_00845(mhpE)
LCJ : NCTC11976_00245(mhpE)
LWA : SAMEA4504053_3185(bphI)
LSS : NCTC12082_02515(bphI)
LADL : NCTC12735_01502(dmpG)
CYQ : Q91_0510 Q91_1491(lapG)
CZA : CYCME_0969(lapG) CYCME_2101(dmpG)
CYY : CPC19_05395(dmpG) CPC19_10505(dmpG)
THIP : N838_12825 N838_24825
HAXH : J4377_02200(dmpG) J4377_11715
APAC : S7S_07000 S7S_13275
MGEO : CFI10_00435(dmpG) CFI10_04585(dmpG) CFI10_04970(dmpG) CFI10_06050(dmpG)
MSEC : LN244_04515(dmpG) LN244_04765(dmpG) LN244_11320(dmpG) LN244_12105(dmpG)
MRZ : KDW95_00755(dmpG) KDW95_22755(dmpG)
NIK : F5I99_02020(dmpG) F5I99_10095(dmpG) F5I99_10510(dmpG)
AJP : AMJAP_2526 AMJAP_2997
ZDF : AN401_03025 AN401_14615
SOK : D0B54_04235(dmpG) D0B54_06190(dmpG)
SINI : GT972_13755(dmpG) GT972_14660(dmpG)
NZO : SAMEA4504057_0444(bphI)
NCI : NCTC10296_00917(bphI)
VMS : LVJ82_04380(dmpG) LVJ82_11885(dmpG)
AQL : BXU06_16260 BXU06_16885 BXU06_17065
RPJ : N234_08170 N234_12195 N234_23020 N234_29155 N234_34815
RIN : ACS15_4356 ACS15_4683
REH : H16_A1807(mhpE2) H16_B0552(mhpE1) H16_B0595(bpHI)
CNC : CNE_1c17880 CNE_2c04980(mhpE) CNE_2c05400(bpHI) CNE_BB1p11950 CNE_BB1p13240
CUH : BJN34_09355 BJN34_24650 BJN34_26430
RME : Rmet_1319(bphI) Rmet_5209(mhpE)
CBW : RR42_m1053 RR42_s1480 RR42_s2315 RR42_s2480
COX : E0W60_03755(dmpG) E0W60_07650(dmpG) E0W60_07795(dmpG) E0W60_08015(dmpG)
CUK : KB879_20210(dmpG) KB879_20415(dmpG) KB879_31595(dmpG)
BPM : BURPS1710b_A0890(mhpE)
BPD : BURPS668_A2590(mhpE)
BPZ : BP1026B_II1937(mhpE)
BHG : I6G56_07585(dmpG) I6G56_27015(dmpG)
BUD : AQ610_12635 AQ610_29480
BVI : Bcep1808_5384 Bcep1808_7605
BUR : Bcep18194_B1188 Bcep18194_B1457 Bcep18194_B2959 Bcep18194_C7644
BCJ : BCAM1615(bphI) BCAM2121
BCEN : DM39_1991(dmpG) DM39_3381(dmpG) DM39_4832(dmpG) DM39_4966(dmpG)
BCEO : I35_5475(bphI) I35_6003
BMUL : NP80_3434(dmpG) NP80_3873(dmpG)
BCED : DM42_4991(dmpG) DM42_6343(dmpG)
BCON : NL30_04130 NL30_24590 NL30_34160
BDF : WI26_15995 WI26_21155 WI26_30230
BTEI : WS51_00570 WS51_05705
BPSL : WS57_03000 WS57_06035 WS57_12155 WS57_12770 WS57_14625
BMEC : WJ16_20010 WJ16_26800
BSTL : BBJ41_10520 BBJ41_21350 BBJ41_33960 BBJ41_34070 BBJ41_34125
BANN : JFN94_18715(dmpG) JFN94_19135(dmpG) JFN94_25660(dmpG) JFN94_26780(dmpG)
BARI : NLX30_30175(dmpG) NLX30_34980(dmpG) NLX30_35035(dmpG) NLX30_35145(dmpG)
BAEN : L3V59_21750(dmpG) L3V59_23075(dmpG) L3V59_23175(dmpG) L3V59_30405(dmpG) L3V59_37685(dmpG)
BGL : bglu_2g02770 bglu_2g05720
BGU : KS03_3374(dmpG) KS03_5342
BUL : BW21_2671(dmpG) BW21_4722(dmpG)
BGP : BGL_2c02530 BGL_2c07540
BPLA : bpln_1g12710 bpln_2g02950 bpln_2g08400
BXE : Bxe_A1152(amnG) Bxe_A3546 Bxe_B2325 Bxe_C1187(bphI)
BXB : DR64_1245(dmpG) DR64_3311(dmpG) DR64_4657(dmpG) DR64_8618(dmpG)
BGE : BC1002_4113 BC1002_4720
BPX : BUPH_04925 BUPH_05357 BUPH_08191
BUZ : AYM40_21230 AYM40_26555
BFN : OI25_255(dmpG) OI25_4591(dmpG)
PARB : CJU94_31730(dmpG) CJU94_37880(dmpG) CJU94_38125(dmpG)
PDIO : PDMSB3_0767.1(mhpE)
PBRY : NDK50_06180(dmpG) NDK50_32885(dmpG)
PPAI : E1956_20835(dmpG) E1956_24320(dmpG) E1956_27310(dmpG) E1956_37230(dmpG) E1956_45895(dmpG)
PHUN : U0042_13225(dmpG) U0042_26780(dmpG)
PPK : U875_01890 U875_05300 U875_16890
PPNO : DA70_08960 DA70_22370
PRB : X636_07580 X636_17530 X636_24965
PUD : G9Q38_01255(dmpG) G9Q38_15010(dmpG)
AALN : Q3V95_01645(dmpG) Q3V95_07650(dmpG)
RLH : MIZ03_0650 MIZ03_1026
ACID : CBP33_01115 CBP33_05420
ACIP : CBP36_01210 CBP36_05870 CBP36_10185
ACIN : CBP34_01120 CBP34_05255 CBP34_10005
ACIS : CBP35_08740 CBP35_13075 CBP35_17740
VBO : CKY39_22055(dmpG) CKY39_28495(dmpG)
CTT : CtCNB1_1351 CtCNB1_3147
CTES : O987_07730 O987_08265
HPSE : HPF_01850(bphI) HPF_15300(mhpE)
HYN : F9K07_02775(dmpG) F9K07_11450(dmpG) F9K07_31030(dmpG)
DIH : G7047_09695(dmpG) G7047_22420(dmpG)
SIMP : C6571_13625(dmpG) C6571_19090(dmpG)
STHM : IS481_10550(dmpG) IS481_17700(dmpG)
METP : C1M51_06440(dmpG) C1M51_16320(dmpG)
SMIO : CATMQ487_04050(mhpE_1) CATMQ487_17590(mhpE_2) CATMQ487_31630(mhpE_3)
JAJ : EKL02_01800(dmpG) EKL02_13150(dmpG)
TMJ : P0M04_05510(dmpG) P0M04_30655(dmpG)
DAR : Daro_0907 Daro_1356 Daro_3238 Daro_3782 Daro_3808
DEY : HYN24_14110(dmpG) HYN24_14200(dmpG)
FLE : KI610_08595(dmpG) KI610_13435(dmpG) KI610_15450(dmpG)
AZO : azo1857(lapG) azo1972(mhpE) azo2431(nahM)
AOA : dqs_2010 dqs_2127 dqs_2575
AZI : AzCIB_1509 AzCIB_4409
AZD : CDA09_09965(dmpG) CDA09_10335(dmpG) CDA09_10460(dmpG) CDA09_21430(dmpG)
AZR : CJ010_12270(dmpG) CJ010_12835(dmpG) CJ010_15205(dmpG)
TMZ : Tmz1t_2079 Tmz1t_3105
THU : AC731_001820 AC731_008905
THAU : C4PIVTH_2809(mhpE) C4PIVTH_4319(mhpE) C4PIVTH_4382(mhpE)
THK : CCZ27_04605(dmpG) CCZ27_10750(dmpG)
THAG : CKCBHOJB_01548(bphI_1) CKCBHOJB_02381(bphI_2)
AZQ : G3580_00550(dmpG) G3580_08280(dmpG)
MTUN : MTUNDRAET4_3892(mhpE)
PHP : PhaeoP97_04061(leuA_2)
PPIC : PhaeoP14_03833(leuA_2)
LEJ : ETW24_22180 ETW24_22845(dmpG)
CON : TQ29_16125 TQ29_16170
SUAM : BOO69_08395 BOO69_22160
AALK : LGT41_0005350(dmpG)
NPP : PP1Y_AT15711 PP1Y_AT31574 PP1Y_AT32722 PP1Y_Mpl3118
NHUM : PQ457_19185(dmpG) PQ457_20595(dmpG)
SMAZ : LH19_00775 LH19_27405
SGI : SGRAN_1422(mhpE2) SGRAN_1579(mhpE)
SWI : Swit_1641 Swit_2113 Swit_4923
SPHD : HY78_14950 HY78_17380
SSAN : NX02_12700 NX02_19005
SPKC : KC8_03550 KC8_19635
SJP : SJA_C1-11910(mhpE_xylK)
SYB : TZ53_09030 TZ53_09335 TZ53_23475
SPHT : K426_04860 K426_12675 K426_22939
SBAR : H5V43_20330(dmpG) H5V43_20635(dmpG) H5V43_22340(dmpG)
SPAG : sphantq_04432(mhpE)
SFLA : SPHFLASMR4Y_02366(bphI)
SPHY : CHN51_06975(dmpG) CHN51_18315(dmpG)
SPHJ : BSL82_10330 BSL82_10435 BSL82_11295
ERY : CP97_03150 CP97_14230
NTD : EGO55_02910(dmpG) EGO55_13670(dmpG)
NCB : C0V82_21140(dmpG) C0V82_23400
TMO : TMO_3169(mhpE) TMO_b0123
ABL : A7H1H_0663 A7H1H_1505
ACIB : ACBT_0259(dmpG) ACBT_1008
AFC : AFAEC_0814 AFAEC_1844(dmpG)
AAQI : AAQM_0982(dmpG) AAQM_1697
ACLO : ACLO_1683 ACLO_a0139(dmpG)
ADZ : ADFLV_2031 ADFLV_2551(dmpG)
APOC : APORC_1168 APORC_1712
AROS : NJU99_01650(dmpG) NJU99_05965
ALK : ALEK_0383(dmpG) ALEK_1376
ALP : LPB137_05825 LPB137_11870
AANA : AANAER_1260(dmpG) AANAER_1283
PBIZ : LWC08_15175 LWC08_15400
BFD : NCTC4823_00793(dmpG)
BACI : B1NLA3E_08435 B1NLA3E_09195 B1NLA3E_11305 B1NLA3E_13970
BACQ : DOE78_06295 DOE78_09230(dmpG)
BMQ : BMQ_1728 BMQ_3587(dmpG)
BMD : BMD_1715 BMD_3572(dmpG)
BMEG : BG04_4046 BG04_461(dmpG)
OCN : CUC15_03680(dmpG) CUC15_04785
GJF : M493_00045 M493_12195(nahM) M493_17920
GTH : Geoth_1679 Geoth_1949
PARG : PspKH34_14920 PspKH34_15480
PASA : BAOM_2840 BAOM_4656
PRD : F7984_08685(dmpG) F7984_12025(dmpG)
RUE : DT065_12685(dmpG) DT065_13790(dmpG) DT065_15115(dmpG) DT065_15205(dmpG)
NDT : L1999_04975(dmpG) L1999_12725 L1999_17445(dmpG)
NCM : QNK12_05505(dmpG) QNK12_09590 QNK12_25615
MLIT : KDJ21_013465 KDJ21_019990
AIA : AWH56_018050(dmpG) AWH56_022475
GAJ : MY490_08570(dmpG) MY490_20825
DOM : RRU94_00820 RRU94_02695
HYI : K2M58_04700(dmpG) K2M58_09710(dmpG)
BAYD : BSPP4475_07465(dmpG)
PMS : KNP414_00502 KNP414_04361
PAEE : R70331_06505 R70331_28775
PBJ : VN24_02345 VN24_03460
PNP : IJ22_00690 IJ22_35270 IJ22_39360 IJ22_48590
PDY : QJQ58_25355(dmpG) QJQ58_29575
PWN : QNH46_07665 QNH46_08355
ANX : ACH33_11590 ACH33_11705
ATHE : K3F53_07235(dmpG) K3F53_07365
ANEU : PP175_03430 PP175_12690(dmpG) PP175_14125(dmpG)
CHEB : HH215_06655(dmpG) HH215_33075
AAD : TC41_0802(mhpE) TC41_1515(mhpE)
ADAU : NZD86_00705(dmpG) NZD86_06135(dmpG)
KYR : CVV65_10345(dmpG) CVV65_11290(dmpG)
FFE : LSG31_10980(dmpG) LSG31_21085(dmpG)
SIV : SSIL_0066(nbaI) SSIL_3690
SSIL : SOLI23_18505 SOLI23_19605
PLIQ : QWY22_04070(dmpG) QWY22_10465(dmpG) QWY22_17950(dmpG)
PSHE : QWY16_03560(dmpG) QWY16_07655(dmpG) QWY16_10565(dmpG) QWY16_17810(dmpG)
PSHX : QWY21_10860(dmpG) QWY21_17795(dmpG)
SPAE : E2C16_04460(dmpG) E2C16_12280(dmpG)
CPAS : Clopa_0658 Clopa_1159
CFM : BJL90_09565 BJL90_19990
RUJ : E5Z56_01690 E5Z56_02990
DOR : Desor_0613 Desor_5186
LACY : A4V08_07730 A4V08_21460
PXV : FXF36_03200 FXF36_03305 FXF36_13160
WCP : H9Q76_01100 H9Q76_07000
WHJ : H9Q79_00330 H9Q79_07650 H9Q79_08190
TIS : P3962_09215 P3962_13175(dmpG)
SELT : BCS37_02355 BCS37_10030
STED : SPTER_03000 SPTER_36960(bphI)
MTU : Rv3469c(mhpE) Rv3534c(hsaF)
MTV : RVBD_3469c RVBD_3534c
MTC : MT3575(bphI-1) MT3638(bphI-2)
MRA : MRA_3509(mhpE) MRA_3573(bphI)
MTF : TBFG_13506 TBFG_13567
MTB : TBMG_03517 TBMG_03574
MTK : TBSG_03539 TBSG_03600
MTZ : TBXG_003488 TBXG_003549
MTG : MRGA327_21385 MRGA327_21835
MTE : CCDC5079_3211 CCDC5079_3275
MTUR : CFBS_3686 CFBS_3750
MTL : CCDC5180_3165 CCDC5180_3227
MTO : MTCTRI2_3537(mhpE) MTCTRI2_3598
MTD : UDA_3469c(mhpE) UDA_3534c
MTN : ERDMAN_3810(mhpE) ERDMAN_3878
MTJ : J112_18655 J112_19030
MTUB : MT7199_3532 MT7199_3596(hsaF)
MTUC : J113_24260 J113_24720
MTUE : J114_18570 J114_18900
MTX : M943_17855 M943_18170
MTUH : I917_24355 I917_24800
MTUL : TBHG_03416 TBHG_03474
MTUT : HKBT1_3672 HKBT1_3735
MTUU : HKBT2_3680 HKBT2_3744
MTQ : HKBS1_3683 HKBS1_3747
MBO : BQ2027_MB3498C(mhpE) BQ2027_MB3564C(hsaf)
MBB : BCG_3534c(mhpE) BCG_3598c
MBT : JTY_3534(mhpE) JTY_3599
MBM : BCGMEX_3532c(mhpE) BCGMEX_3596c
MBK : K60_036050 K60_036720
MAF : MAF_34840(mhpE) MAF_35460
MMIC : RN08_3829 RN08_3910
MCE : MCAN_34851(mhpE) MCAN_35451
MCQ : BN44_110026(hsaF) BN44_80145
MCV : BN43_70136 BN43_90032(hsaF)
MCX : BN42_50147 BN42_90029
MCZ : BN45_100029(hsaF) BN45_70127
MORY : MO_003627 MO_003691(dmpG)
MSER : MTY59_24680(bphI-2)
MSA : Mycsm_01981 Mycsm_05771
MMAE : MMARE11_14060 MMARE11_48310
MLI : MULP_01624 MULP_05273
MPSE : MPSD_43480(mhpE) MPSD_52200
MSHO : MSHO_04940 MSHO_21830(mhpE)
MKN : MKAN_11835 MKAN_22345
MYV : G155_04640 G155_08465
MDX : BTO20_24365 BTO20_31190
MSHG : MSG_03538(mhpE) MSG_04519(bphI-2)
MFJ : MFLOJ_23740 MFLOJ_41030(bphI-2)
MSTO : MSTO_45000(bphI-2) MSTO_55740 MSTO_55750
MSAK : MSAS_13470(mhpE) MSAS_28750(bphI-2) MSAS_43780
MLW : MJO58_19415(dmpG) MJO58_24895(dmpG)
MPAG : C0J29_01125(dmpG) C0J29_27545(dmpG) C0J29_30935(dmpG)
MGOR : H0P51_01125(dmpG) H0P51_02525(dmpG) H0P51_25600(dmpG)
MCOO : MCOO_26850(bphI-2) MCOO_46660(mhpE)
MBAI : MB901379_03149 MB901379_04413
MSEO : MSEO_27460(mhpE) MSEO_34130(bphI-2)
MGAU : MGALJ_37980(bphI-2)
MLJ : MLAC_00060 MLAC_00640(mhpE) MLAC_47800
MBRD : MBRA_01260(mhpE) MBRA_20390
MOT : LTS72_00350 LTS72_28135(dmpG)
MPAA : MKK62_02615(dmpG) MKK62_17480(dmpG)
MKY : IWGMT90018_02270(mhpE) IWGMT90018_56950(bphI-2)
MADI : A7U43_06955 A7U43_08565
MYW : BVC93_08910 BVC93_16785 BVC93_18840
MSM : MSMEG_4150 MSMEG_5937
MSG : MSMEI_4052 MSMEI_5778(bphI-2)
MSB : LJ00_20580 LJ00_29360
MSN : LI99_20585 LI99_29365
MSH : LI98_20590 LI98_29370
MVA : Mvan_0597 Mvan_4391 Mvan_5234
MCB : Mycch_1595 Mycch_4599
MNE : D174_16930 D174_24265
MYN : MyAD_16595 MyAD_23805
MFT : XA26_08870 XA26_16940 XA26_21640
MLL : B1R94_19665 B1R94_24980
MTHN : 4412656_04050(bphI)
MHAS : MHAS_03727 MHAS_04021(mhpE)
MCHT : MCHIJ_19800(bphI-2)
MAUU : NCTC10437_01140(mhpE) NCTC10437_02746(bphI_1) NCTC10437_04999(bphI_2)
MMAG : MMAD_42140 MMAD_47980(bphI-2)
MAIC : MAIC_05760(bphI-2) MAIC_22100
MIJ : MINS_00180(bphI-2_1) MINS_43250(bphI-2_2)
MTY : MTOK_07660 MTOK_22760(bphI-2)
MPSC : MPSYJ_16300(bphI-2)
MARZ : MARA_21770 MARA_48410(bphI-2)
MHEV : MHEL_01570 MHEL_28230(bphI-2) MHEL_40950(mhpE)
MANY : MANY_02560(mhpE) MANY_32600(bphI-2)
MAUB : MAUB_26340 MAUB_47410(mhpE)
MPOF : MPOR_20400 MPOR_53420(bphI-2)
MPHU : MPHO_21660(mhpE) MPHO_44020(bphI-2)
MMUC : C1S78_007395(dmpG) C1S78_025280(dmpG)
MMAT : MMAGJ_34850(bphI-2) MMAGJ_45410(mhpE)
MBOK : MBOE_04190(bphI-2) MBOE_53430(mhpE)
MSEI : MSEDJ_01970(bphI-2)
MFLV : NCTC10271_00510(bphI)
MMON : EWR22_21675(dmpG) EWR22_25190(dmpG)
MGO : AFA91_00035 AFA91_00925 AFA91_11080 AFA91_19720
MPAE : K0O64_09025(dmpG) K0O64_25850(dmpG)
MRF : MJO55_02095(dmpG) MJO55_23900(dmpG)
MCRO : MI149_09925(dmpG) MI149_26160(dmpG)
MGRO : FZ046_02630(dmpG) FZ046_24415(dmpG)
MAUS : JN090_01875(dmpG) JN090_26005(dmpG) JN090_26235(dmpG)
MFRE : EXE63_19000(dmpG) EXE63_21975(dmpG)
MKR : MKOR_35810(bphI-2) MKOR_36590
MIZ : BAB75_03750 BAB75_13810
MTER : 4434518_03651(bphI)
MMIN : MMIN_05360(mhpE) MMIN_06630(bphI-2_1) MMIN_12010(bphI-2_2)
MHIB : MHIB_23770(bphI-2_1) MHIB_30690(bphI-2_2)
COK : COCCU_04410 COCCU_04895
NFA : NFA_30510 NFA_33200 NFA_4670
NFR : ERS450000_00749(dmpG_1) ERS450000_01014(dmpG_2) ERS450000_03770(mhpE)
NNO : NONO_c04940 NONO_c35100 NONO_c51400(mhpE)
NSL : BOX37_02155 BOX37_11725
NTP : CRH09_03205(dmpG) CRH09_30225(dmpG) CRH09_31415
NAD : NCTC11293_01237(mhpE_1) NCTC11293_04251(mhpE_2) NCTC11293_04415(mhpE_3)
NWL : NWFMUON74_04890(bphI-2) NWFMUON74_37270
NTC : KHQ06_03695(dmpG) KHQ06_23930(dmpG)
NGP : LTT66_15385(dmpG) LTT66_28995(dmpG) LTT66_34600(dmpG)
NSPU : IFM12276_01600 IFM12276_29230
RHA : RHA1_ro00515 RHA1_ro03867 RHA1_ro04535(hsaF) RHA1_ro05801 RHA1_ro08083(bphF3) RHA1_ro09019(bphF1) RHA1_ro10112(bphF4)
REB : XU06_03840 XU06_27800
RQI : C1M55_04085(dmpG) C1M55_29425(dmpG)
ROP : ROP_34160(cmtG) ROP_37360 ROP_44500 ROP_54050 ROP_58620 ROP_pROB02-02240
ROA : Pd630_LPD00986 Pd630_LPD02420 Pd630_LPD12053
RPY : Y013_12505 Y013_15605
RBY : CEJ39_02110(dmpG) CEJ39_23375(dmpG)
RAV : AAT18_03900 AAT18_08165 AAT18_09385 AAT18_22070
RRZ : CS378_11835(dmpG) CS378_19560(dmpG) CS378_23185(dmpG) CS378_24200(dmpG)
RHQ : IM25_04130 IM25_05560
RHOD : AOT96_09095 AOT96_14480
RCR : NCTC10994_02788(dmpG)
RTM : G4H71_04585(dmpG) G4H71_07415(dmpG)
RKO : JWS14_19325(dmpG) JWS14_24465(dmpG) JWS14_31725(dmpG) JWS14_41340(dmpG) JWS14_47125(dmpG)
RGO : KYT97_14725(dmpG) KYT97_23115(dmpG)
ROZ : CBI38_00780 CBI38_04150 CBI38_22805 CBI38_27970 CBI38_30695
RPSK : JWS13_02205(dmpG) JWS13_12185(dmpG) JWS13_12610(dmpG) JWS13_19020(dmpG) JWS13_20460(dmpG) JWS13_25445(dmpG)
RHOO : RA302_03960(dmpG) RA302_28195(dmpG)
RHOU : KZJ41_03890(dmpG) KZJ41_08730(dmpG) KZJ41_10530(dmpG) KZJ41_23500(dmpG)
RHOW : A4U64_02480 A4U64_15215 A4U64_16415 A4U64_20875
RHOJ : JVH1_07355(dmpG) JVH1_13655(dmpG) JVH1_17185(dmpG) JVH1_33685(dmpG) JVH1_35310(dmpG) JVH1_41765(dmpG)
RHOS : QWW67_12150(dmpG) QWW67_21230(dmpG) QWW67_26055(dmpG) QWW67_27235(dmpG)
RHOQ : QWW98_12160(dmpG) QWW98_21240(dmpG) QWW98_26080(dmpG) QWW98_27255(dmpG)
RHOY : QNA09_01465(dmpG) QNA09_05830(dmpG) QNA09_06880(dmpG) QNA09_19350(dmpG)
GTA : BCM27_05050 BCM27_21880
GRU : GCWB2_04125 GCWB2_17410(mhpE)
GOM : D7316_02537(mhpE) D7316_02561
GAV : C5O27_00905(dmpG) C5O27_10800(dmpG)
GOD : GKZ92_03925(dmpG) GKZ92_16330(dmpG)
GOS : QAD21_04070(dmpG) QAD21_20920(dmpG)
GOJ : GR168_04210(dmpG) GR168_19980(dmpG) GR168_23115(dmpG)
GAM : GII34_11005(dmpG) GII34_19575(dmpG)
GPD : GII33_03280(dmpG) GII33_08540(dmpG) GII33_16065(dmpG) GII33_21665(dmpG)
GJI : H1R19_04000(dmpG) H1R19_16275(dmpG)
GOI : LK459_05115(dmpG) LK459_10075(dmpG)
GHN : MVF96_04205(dmpG) MVF96_20935(dmpG)
SPIN : KV203_17385(dmpG) KV203_17515(dmpG)
TPUL : TPB0596_41360(mhpE)
DIZ : CT688_01915(dmpG) CT688_03155(dmpG)
SANL : KZO11_33875(dmpG) KZO11_35850(dmpG)
SCYE : R2B67_01905(dmpG) R2B67_33980
SCB : SCAB_15191 SCAB_2071(mhpE)
SRC : M271_00330 M271_09210 M271_50390
SMAL : SMALA_6710 SMALA_7757 SMALA_8340
SSOI : I1A49_37320(dmpG) I1A49_42625(dmpG) I1A49_45440
SDV : BN159_1388 BN159_4098
SALS : SLNWT_0147 SLNWT_5105 SLNWT_6915
SVT : SVTN_17135 SVTN_35865
SLE : sle_57500(sle_57500)
STSI : A4E84_21300 A4E84_36455
SCAD : DN051_00520(dmpG) DN051_40290(dmpG)
SPLU : LK06_002775 LK06_031945
SNK : CP967_03290(dmpG) CP967_06135(dmpG)
SGF : HEP81_01293(dmpG) HEP81_01862
SBRO : GQF42_30040 GQF42_36630
SROI : IAG44_01285(dmpG) IAG44_01910 IAG44_02040(dmpG) IAG44_17905
SLF : JEQ17_43995(dmpG) JEQ17_44820(dmpG)
SLON : LGI35_13875(dmpG) LGI35_42280(dmpG)
STUD : STRTU_001457(dmpG) STRTU_001635(dmpG)
SANT : QR300_07705(dmpG) QR300_10245(dmpG)
STRW : QHG49_00605 QHG49_07845
STRI : C7M71_004275 C7M71_005340(dmpG)
AMAU : DSM26151_04180(mhpE)
ARTP : E5206_04525(dmpG) E5206_14565(dmpG)
ACIT : HPK19_02430(dmpG) HPK19_16630
ASUN : KG104_01715(dmpG) KG104_04170(dmpG)
OCP : NF557_14860(dmpG) NF557_15615(dmpG)
RAIN : Rai3103_00290(dmpG)
NDK : I601_0557(mhpE) I601_3471
NARO : CFH99_00775(dmpG) CFH99_13570(dmpG)
NPI : G7071_04105(dmpG) G7071_15955(dmpG)
NMAR : HPC71_09505(dmpG) HPC71_13435(dmpG)
NFC : KG111_01315(dmpG) KG111_08285(dmpG)
NBI : SHK19_12540(dmpG) SHK19_15670(dmpG)
NOF : MF408_08975(dmpG) MF408_21015(dmpG)
PSIM : KR76_14485 KR76_24170
AGRA : AGRA3207_000998(dmpG)
ACTQ : OG417_34530(dmpG) OG417_40170(dmpG) OG417_51230(dmpG)
FRE : Franean1_2882 Franean1_4743
FRI : FraEuI1c_4108 FraEuI1c_5353
AORI : SD37_09820 SD37_18940
AACD : LWP59_08640 LWP59_14835(dmpG) LWP59_38175(dmpG)
AROO : NQK81_00860(dmpG) NQK81_04125(dmpG)
ARHD : VSH64_13785(dmpG) VSH64_19085(dmpG) VSH64_22200(dmpG) VSH64_30310(dmpG) VSH64_31450(dmpG)
AMOG : QRX60_29040(dmpG) QRX60_35165(dmpG) QRX60_43770
ACOR : LCL61_24555(dmpG) LCL61_26305(dmpG) LCL61_28760(dmpG)
ANW : QP939_26555(dmpG) QP939_43155(dmpG)
PSEQ : AD006_28425 AD006_28725
PECQ : AD017_28815 AD017_29115
KUT : JJ691_07890 JJ691_11970 JJ691_97930(dmpG)
LED : BBK82_06910 BBK82_38930 BBK82_43185
ALO : CRK56593 CRK57279 CRK57814 CRK59599
UME : RM788_04360 RM788_13235(dmpG)
VMA : VAB18032_17785 VAB18032_28746
MCRA : ID554_06975(dmpG) ID554_07045(dmpG) ID554_30895(dmpG)
VER : HUT12_12160(dmpG) HUT12_13560(dmpG) HUT12_26055(dmpG)
MENO : Jiend_06570(mhpE) Jiend_41030
MICF : QQG74_13330(dmpG) QQG74_25590(dmpG)
ACTR : Asp14428_11560 Asp14428_49220
ACTE : ACTI_41130 ACTI_45950
PLK : CIK06_08080(dmpG) CIK06_17415(dmpG)
PSUU : Psuf_010690 Psuf_068150(mhpE)
PRY : Prubr_10600 Prubr_51680 Prubr_59250 Prubr_63370
DFU : Dfulv_20740(dmpG) Dfulv_27720(dmpG) Dfulv_33585(dmpG)
DACT : KZZ52_16470(dmpG) KZZ52_31205(dmpG)
BALA : DSM104299_03998 DSM104299_05642
CWO : Cwoe_0441 Cwoe_4743 Cwoe_4833
SBAE : DSM104329_01249 DSM104329_04660
TRC : DYE49_06825 DYE49_08395
TPAV : HRQ91_08700 HRQ91_08705
PYY : RAH42_06880 RAH42_09730
FUA : LVD17_10815 LVD17_25545
CPRV : CYPRO_2437 CYPRO_2456
NAJ : B1756_14020 B1756_15945
» show all
Taxonomy
Reference
Authors
Manjasetty BA, Powlowski J, Vrielink A
Title
Crystal structure of a bifunctional aldolase-dehydrogenase: sequestering a reactive and volatile intermediate.
Journal
Sequence
Reference
Authors
Powlowski J, Sahlman L, Shingler V
Title
Purification and properties of the physically associated meta-cleavage pathway enzymes 4-hydroxy-2-ketovalerate aldolase and aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600.
Journal
Sequence
Reference
Authors
Manjasetty BA, Croteau N, Powlowski J, Vrielink A.
Title
Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase--aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600.
Journal
Reference
Authors
Baker P, Carere J, Seah SY
Title
Probing the molecular basis of substrate specificity, stereospecificity, and catalysis in the class II pyruvate aldolase, BphI.
Journal
Sequence
Reference
Authors
Baker P, Hillis C, Carere J, Seah SY
Title
Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes.
Journal
Sequence
Reference
Authors
Baker P, Seah SY
Title
Rational design of stereoselectivity in the class II pyruvate aldolase BphI.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.1.3.39
ExPASy - ENZYME nomenclature database: 4.1.3.39
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.3.39
LinkDB
All DBs