KEGG   ORTHOLOGY: K01841
Entry
K01841                      KO                                     
Symbol
pepM
Name
phosphoenolpyruvate phosphomutase [EC:5.4.2.9]
Pathway
map00440  Phosphonate and phosphinate metabolism
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K01841  pepM; phosphoenolpyruvate phosphomutase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K01841  pepM; phosphoenolpyruvate phosphomutase
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.2  Phosphotransferases (phosphomutases)
    5.4.2.9  phosphoenolpyruvate mutase
     K01841  pepM; phosphoenolpyruvate phosphomutase
Other DBs
RN: R00661
COG: COG2513
GO: 0050188
Genes
ZNE: 110838650
CSEC: 111872613
FCD: 110846421
LGI: LOTGIDRAFT_228330
PCAN: 112561240
BGT: 106079080
GAE: 121367841
CRG: 105327128 117692442
MYI: 110459395
PMAX: 117333732
MMER: 123533891
OBI: 106868978
OSN: 115222540
LAK: 106181605
NVE: 5508858
EPA: 110252232
ATEN: 116289673
ADF: 107334552
AMIL: 114960205
PDAM: 113681042
SPIS: 111330077
DGT: 114532990
XEN: 124434290
HMG: 100204901
HDE: HDEF_0203
SRL: SOD_c30090(bcpB)
FSM: CCS41_00895(aepX)
ECA: ECA0487(fom1)
PATR: EV46_02520
PATO: GZ59_05030(fom1)
PCT: PC1_0476
PEC: W5S_0590
PPUJ: E2566_02925(aepX)
PARI: I2D83_19365(aepX)
PPAV: LOZ86_04705(aepX)
LBQ: CKQ53_06560(aepX)
LPOP: I6N93_15650(aepX)
SOD: Sant_3984(pepM)
EPE: CI789_05510(aepX)
PAM: PANA_3291(pepM)
PLU: plu1865
XBV: XBW1_2042
XDO: XDD1_1002(PEPM)
XVA: C7V42_03530(aepX)
XHY: FZ025_12110(aepX)
VFI: VF_1249
PSYR: N018_11280
PFL: PFL_2141(aepX)
PPRC: PFLCHA0_c21830(pphA)
PPRO: PPC_2159(aepX)
PFC: PflA506_4617(aepX)
PEN: PSEEN3956
PSOS: POS17_2086(aepX)
PVW: HU752_022625(aepX)
PANH: HU763_013985(aepX)
SDN: Sden_1161
NOC: Noc_1317
NHL: Nhal_1306
NWA: Nwat_1199
NWR: E3U44_16825(aepX)
RME: Rmet_1808(pepM)
CPAU: EHF44_14440(aepX)
COX: E0W60_18815(aepX)
BMA: BMAA1768(pepM)
BMV: BMASAVP1_0758(pepM)
BML: BMA10229_1051(pepM)
BMN: BMA10247_A2026(pepM)
BMAL: DM55_4014(aepX)
BMAQ: DM76_4710(aepX)
BMAI: DM57_07165
BMAF: DM51_3461(aepX)
BMAZ: BM44_3974(aepX)
BMAB: BM45_4751(aepX)
BPM: BURPS1710b_A2065(pepM)
BPSE: BDL_3735(aepX) BDL_3837(aepX)
BPSM: BBQ_5585(aepX) BBQ_5687(aepX)
BPSU: BBN_3909(aepX) BBN_4009(aepX)
BPSD: BBX_5572(aepX) BBX_5674(aepX)
BPK: BBK_3881(aepX) BBK_5714(aepX)
BPSH: DR55_4742(aepX) DR55_4843(aepX)
BPSA: BBU_5436(aepX) BBU_5538(aepX)
BPSO: X996_3790(aepX) X996_4593(aepX)
BUT: X994_4009(aepX) X994_4111(aepX)
BTQ: BTQ_5190(aepX)
BTJ: BTJ_3820(aepX)
BTZ: BTL_4576(aepX) BTL_4676(aepX)
BTD: BTI_5338(aepX) BTI_5422
BTV: BTHA_5553(aepX)
BTHE: BTN_4315(aepX)
BTHM: BTRA_4580(aepX)
BTHL: BG87_4647(aepX)
BOK: DM82_4611(aepX) DM82_4705(aepX) DM82_5468(aepX)
BOC: BG90_2213(aepX) BG90_5140(aepX) BG90_5888(aepX) BG90_5980(aepX)
BVE: AK36_4232(aepX)
BCN: Bcen_4245
BCJ: BCAM1245
BCEN: DM39_3753(aepX)
BCEW: DM40_4163(aepX)
BCEO: I35_5094
BAM: Bamb_3535
BMU: Bmul_4471
BMK: DM80_3632(aepX)
BMUL: NP80_4148(aepX)
BCT: GEM_4495
BCED: DM42_3846(aepX)
BDL: AK34_4230(aepX)
BCON: NL30_06370
BUB: BW23_4919(aepX)
BLAT: WK25_23150
BTEI: WS51_03920
BSEM: WJ12_26085
BPSL: WS57_07790
BMEC: WJ16_24710
BANN: JFN94_23430(aepX)
BGU: KS03_4595(aepX)
BGO: BM43_5003(aepX)
BUK: MYA_4542
BUL: BW21_5018(aepX)
BURK: DM992_19615(aepX)
BXE: Bxe_B2235
BXB: DR64_4566(aepX)
BPH: Bphy_3822
BFN: OI25_4536(aepX)
PSPW: BJG93_18660(aepX)
PARB: CJU94_32420(aepX)
PHS: C2L64_30760(aepX)
PTER: C2L65_27420(aepX)
PGP: CUJ91_19555(aepX)
PCJ: CUJ87_30240(aepX)
PTS: CUJ90_26940(aepX)
PMEG: FNZ07_08530(aepX)
PTRO: G5S35_19400(aepX)
PGIS: I6I06_19275(aepX)
PACP: FAZ97_15190(aepX)
PACS: FAZ98_20205(aepX)
PEW: KZJ38_30035(aepX)
PPNO: DA70_09035
PPNM: LV28_21770
PSPU: NA29_20990
PAPI: SG18_00140
PAND: DRB87_06680(aepX)
PFIB: PI93_020425(aepX)
CABA: SBC2_10680(prpB_1)
BPAR: BN117_3742(pepM)
BBH: BN112_2401(pepM)
BBR: BB1046(pepM)
BBM: BN115_0996(pepM)
BBX: BBS798_1016(pepM)
BHO: D560_3796
BHM: D558_3769
BHZ: ACR54_02067(pphA_1)
AXX: ERS451415_04691(pphA_2)
AFQ: AFA_00195
AAV: Aave_3887
AAA: Acav_2122
CJU: C8J_1331
PCA: Pcar_0628
PPD: Ppro_2167
SCL: sce7305(pepM)
MJR: EB229_33300(aepX)
MERD: EB233_30950(aepX)
EMX: FKV68_24015(aepX)
AVI: Avi_3412
RJG: CCGE525_35255(aepX)
AOL: S58_09510
BGQ: X265_36095(aepX)
BGZ: XH91_35300(aepX)
BARH: WN72_10290(aepX) WN72_10315
BVZ: BRAD3257_7243(bcpB)
RPC: RPC_3871
SIW: GH266_09715(aepX)
THAA: CFI11_00245(aepX)
ROS: CTJ15_07640(aepX)
RMUC: FOB66_09665(aepX)
RMT: IAI58_18640(aepX)
LCK: HN018_01540(aepX)
SHUM: STHU_42930(pepM)
SVC: STVA_42000(pepM)
STEL: STAQ_05370(pepM)
AZZ: DEW08_28020(aepX)
MAGX: XM1_0907(pepM)
TMO: TMO_b0348
BSTO: C0V70_16040(aepX)
BSS: BSUW23_01000(rhiH)
BYA: BANAU_0589(pepM)
BQY: MUS_0647
BAMB: BAPNAU_0598(pepM)
BMP: NG74_00659(pphA)
BACB: OY17_06005
BMQ: BMQ_0784(aepX)
BMD: BMD_0785(aepX)
BMEG: BG04_3078(aepX)
PARH: I5S86_23670(aepX)
PTB: DER53_11735(aepX)
PCAL: BV455_03446(pphA)
MEKU: HUW50_16405(aepX)
BOU: I5818_22340(aepX)
BRW: GOP56_09095(aepX)
PPOL: X809_41430
PLV: ERIC2_c18340(bcpB) ERIC2_c19750(pphA)
PLUT: EI981_13655(aepX)
PCHI: PC41400_18315(aepX)
TAB: CIG75_00855(aepX) CIG75_11125(aepX)
KEB: GXN75_05285(aepX)
RCH: RUM_11420
SDV: BN159_4099(pphA)
SALS: SLNWT_1191
SALF: SMD44_04407(pepM)
SGD: ELQ87_04600(aepX)
SRIM: CP984_37460(aepX)
KSK: KSE_22660
FAL: FRAAL6377
AMYY: YIM_29505(pphA)
KAL: KALB_5539
ACTA: C1701_23200(aepX)
SAQ: Sare_1956
NED: HUN01_29215(aepX)
TOQ: HCG51_21875(aepX)
OBG: Verru16b_03222(pphA)
FUV: JR347_10760(aepX)
NDE: NIDE2903
NMV: NITMOv2_0598(pepM)
NJA: NSJP_1710
NMR: Nmar_0160
NCT: NMSP_0156
AG: AAA30123(PEPM)
 » show all
Reference
PMID:2160937
  Authors
Hidaka T, Imai S, Hara O, Anzai H, Murakami T, Nagaoka K, Seto H
  Title
Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.
  Journal
J Bacteriol 172:3066-72 (1990)
DOI:10.1128/JB.172.6.3066-3072.1990
LinkDB

KEGG   ORTHOLOGY: K23999
Entry
K23999                      KO                                     
Symbol
fom1
Name
phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase [EC:5.4.2.9 2.7.7.104]
Pathway
map00440  Phosphonate and phosphinate metabolism
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K23999  fom1; phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K23999  fom1; phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.104  2-hydroxyethylphosphonate cytidylyltransferase
     K23999  fom1; phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.2  Phosphotransferases (phosphomutases)
    5.4.2.9  phosphoenolpyruvate mutase
     K23999  fom1; phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase
Other DBs
RN: R00661 R12498
COG: COG2513 COG0615
GO: 0050188
Genes
OSG: BST96_06905
MPRF: J8N69_05410(aepX)
PHN: PAEH1_00300
MEU: ACJ67_08960
AZO: azo2698(pepM)
AOA: dqs_2833
HCP: HCN_1062
HCB: HCBAA847_0912
HWI: A0Z60_07480(aepX)
CHYO: CHH_1593
CHW: A2J15_004815(aepX)
CINF: CINF_1344
DAL: Dalk_1323
ECOG: FIV45_08000(aepX)
CTC: CTC_01698
CBE: Cbei_4338
CBZ: Cbs_4338
CBEI: LF65_04862
CSR: Cspa_c46190(ppm)
CSB: CLSA_c08730(ppm)
CDY: F3K33_22185(aepX)
CCAA: KQH81_02885(aepX)
RIX: RO1_19910
SAIU: J4H86_04280(aepX)
NHY: JQS43_02325(aepX)
SNA: Snas_5665
NAV: JQS30_13655(aepX)
OLS: Olsu_0594
TDE: TDE_1413
TPHG: FUT81_06855(aepX)
TRI: DYE50_04590(aepX)
TPAV: HRQ91_06190(aepX)
BHC: JFL75_01540(aepX)
FSC: FSU_1439
BTH: BT_1720
BTHO: Btheta7330_01295(pphA)
BFS: BF9343_1814(aepX)
BSTE: K6V31_00385(aepX)
PCOI: LK433_14490(aepX)
DRC: G0Q07_19260(aepX)
NLI: G3M70_12635(aepX)
PSYT: DSAG12_01622(ribL_1)
AG: BAA32495(fom1)
 » show all
Reference
  Authors
Cho SH, Kim SY, Tomita T, Shiraishi T, Park JS, Sato S, Kudo F, Eguchi T, Funa N, Nishiyama M, Kuzuyama T
  Title
Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme.
  Journal
ACS Chem Biol 12:2209-2215 (2017)
DOI:10.1021/acschembio.7b00419
  Sequence
LinkDB

KEGG   ENZYME: 5.4.2.9
Entry
EC 5.4.2.9                  Enzyme                                 
Name
phosphoenolpyruvate mutase;
phosphoenolpyruvate-phosphonopyruvate phosphomutase;
PEP phosphomutase;
phosphoenolpyruvate phosphomutase;
PEPPM;
PEP phosphomutase
Class
Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)
Sysname
phosphoenolpyruvate 2,3-phosphonomutase
Reaction(IUBMB)
phosphoenolpyruvate = 3-phosphonopyruvate [RN:R00661]
Reaction(KEGG)
R00661
Substrate
phosphoenolpyruvate [CPD:C00074]
Product
3-phosphonopyruvate [CPD:C02798]
Comment
Involved in the biosynthesis of the C-P bond, although the equilibrium greatly favours phosphoenolpyruvate.
History
EC 5.4.2.9 created 1990
Pathway
ec00440  Phosphonate and phosphinate metabolism
ec00998  Biosynthesis of various antibiotics
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
Orthology
K01841  phosphoenolpyruvate phosphomutase
K23999  phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase
Genes
ZNE110838650
CSEC111872613
FCD110846421
LGILOTGIDRAFT_228330
PCAN112561240
BGT106079080
GAE121367841
CRG105327128 117692442
MYI110459395
PMAX117333732
MMER123533891
OBI106868978
OSN115222540
LAK106181605
NVE5508858
EPA110252232
ATEN116289673
ADF107334552
AMIL114960205
PDAM113681042
SPIS111330077
DGT114532990
XEN124434290
HMG100204901
TMNUCRPA7_8548
PSCOLY89DRAFT_26512
TETTTHERM_00022810
PTMGSPATT00017928001 GSPATT00022184001
TCR508851.189 511589.140
HDEHDEF_0203
SRLSOD_c30090(bcpB)
FSMCCS41_00895(aepX)
ECAECA0487(fom1)
PATREV46_02520
PATOGZ59_05030(fom1)
PCTPC1_0476
PCCPCC21_005010
PWAPecwa_0572
PPARA8F97_15530
PECW5S_0590
PWSA7983_10780
PPOABJK05_19415
PPUJE2566_02925(aepX)
PARII2D83_19365(aepX)
PPAVLOZ86_04705(aepX)
LBQCKQ53_06560(aepX)
LPOPI6N93_15650(aepX)
SODSant_3984(pepM)
EPECI789_05510(aepX)
PAMPANA_3291(pepM)
PLFPANA5342_0777(pepM) PANA5342_2583
PAQPAGR_g0790 PAGR_g3818
PLUplu1865
PLUMA4R40_09345
XBVXBW1_2042
XDOXDD1_1002(PEPM)
EICNT01EI_2703
XVAC7V42_03530(aepX)
XHYFZ025_12110(aepX)
VFIVF_1249
PMOSO165_002420
PSYRN018_11280
PFLPFL_2141(aepX)
PPRCPFLCHA0_c21830(pphA)
PPROPPC_2159(aepX)
PFCPflA506_4617(aepX)
PPZH045_01960
PENPSEEN3956
PSOSPOS17_2086(aepX)
PVWHU752_022625(aepX)
PANHHU763_013985(aepX)
SDNSden_1161
OSGBST96_06905
NOCNoc_1317
NHLNhal_1306
NWANwat_1199
NWRE3U44_16825(aepX)
NTGNSCAC_0558
ZPLZBT109_1640
MPRFJ8N69_05410(aepX)
RPJN234_04640
RMERmet_1808(pepM)
CBWRR42_s0339
CCUPBKK81_29240
CUPBKK80_27115
CUUBKK79_33035
CPAUEHF44_14440(aepX)
COXE0W60_18815(aepX)
BMABMAA1768(pepM)
BMVBMASAVP1_0758(pepM)
BMLBMA10229_1051(pepM)
BMNBMA10247_A2026(pepM)
BMALDM55_4014(aepX)
BMAQDM76_4710(aepX)
BMAIDM57_07165
BMAFDM51_3461(aepX)
BMAZBM44_3974(aepX)
BMABBM45_4751(aepX)
BPSBPSS0509 BPSS0610
BPMBURPS1710b_A2065(pepM)
BPLBURPS1106A_A0691(pepM) BURPS1106A_A0818
BPDBURPS668_A0780 BURPS668_A0910
BPSEBDL_3735(aepX) BDL_3837(aepX)
BPSMBBQ_5585(aepX) BBQ_5687(aepX)
BPSUBBN_3909(aepX) BBN_4009(aepX)
BPSDBBX_5572(aepX) BBX_5674(aepX)
BPZBP1026B_II0564 BP1026B_II0674
BPQBPC006_II0735 BPC006_II0866
BPKBBK_3881(aepX) BBK_5714(aepX)
BPSHDR55_4742(aepX) DR55_4843(aepX)
BPSABBU_5436(aepX) BBU_5538(aepX)
BPSOX996_3790(aepX) X996_4593(aepX)
BUTX994_4009(aepX) X994_4111(aepX)
BTEBTH_II1908
BTQBTQ_5190(aepX)
BTJBTJ_3820(aepX)
BTZBTL_4576(aepX) BTL_4676(aepX)
BTDBTI_5338(aepX) BTI_5422
BTVBTHA_5553(aepX)
BTHEBTN_4315(aepX)
BTHMBTRA_4580(aepX)
BTHADR62_4261 DR62_4364
BTHLBG87_4647(aepX)
BOKDM82_4611(aepX) DM82_4705(aepX) DM82_5468(aepX)
BOCBG90_2213(aepX) BG90_5140(aepX) BG90_5888(aepX) BG90_5980(aepX)
BUUWS70_20055 WS70_24280
BSAVWS86_03985 WS86_21240 WS86_21655
BVIBcep1808_4687
BVEAK36_4232(aepX)
BURBcep18194_B1914
BCNBcen_4245
BCHBcen2424_4121
BCMBcenmc03_3398
BCJBCAM1245
BCENDM39_3753(aepX)
BCEWDM40_4163(aepX)
BCEOI35_5094
BAMBamb_3535
BACBamMC406_4016
BMUBmul_4471
BMKDM80_3632(aepX)
BMULNP80_4148(aepX)
BCTGEM_4495
BCEDDM42_3846(aepX)
BCEPAPZ15_18450
BDLAK34_4230(aepX)
BPYRABD05_29915
BCONNL30_06370
BUBBW23_4919(aepX)
BDFWI26_19325
BLATWK25_23150
BTEIWS51_03920
BSEMWJ12_26085
BPSLWS57_07790
BMECWJ16_24710
BSTGWT74_17330 WT74_25015
BANNJFN94_23430(aepX)
BGLbglu_2g13460
BGUKS03_4595(aepX)
BUGBC1001_5203
BGFBC1003_4280
BGDbgla_2g13360
BGOBM43_5003(aepX)
BYIBYI23_A006810
BUKMYA_4542
BUEBRPE67_ACDS06750
BULBW21_5018(aepX)
BUQAC233_24010
BGPBGL_2c11770
BPLAbpln_2g12610
BUDAQ610_28100
BUMAXG89_10160
BUIAX768_03885
BURKDM992_19615(aepX)
BXEBxe_B2235
BXBDR64_4566(aepX)
BPHBphy_3822
BGEBC1002_3393
BPXBUPH_05878
BPYBphyt_5999
BUZAYM40_23410
BFNOI25_4536(aepX)
BCAIK788_0000151
PSPWBJG93_18660(aepX)
PARABTO02_27435
PARBCJU94_32420(aepX)
PHSC2L64_30760(aepX)
PTERC2L65_27420(aepX)
PGPCUJ91_19555(aepX)
PCJCUJ87_30240(aepX)
PTSCUJ90_26940(aepX)
PCAFDSC91_002024
PMEGFNZ07_08530(aepX)
PTROG5S35_19400(aepX)
PGISI6I06_19275(aepX)
PACPFAZ97_15190(aepX)
PACSFAZ98_20205(aepX)
PEWKZJ38_30035(aepX)
BRHRBRH_02824
PPKU875_16965
PPNODA70_09035
PPNMLV28_21770
PRBX636_17455
PPULRO07_15785 RO07_16160
PSPUNA29_20990
PAPISG18_00140
PVEUC34_07420
POXMB84_11760
PFGAB870_18110
PNRAT302_26645
PANDDRB87_06680(aepX)
PFIBPI93_020425(aepX)
CABASBC2_10680(prpB_1)
BUOBRPE64_ACDS07730
BPARBN117_3742(pepM)
BBHBN112_2401(pepM)
BBRBB1046(pepM)
BBMBN115_0996(pepM)
BBXBBS798_1016(pepM)
BHOD560_3796
BHMD558_3769
BHZACR54_02067(pphA_1)
BBROBAU06_01990
BPDZBBN53_11400
AXYAXYL_04811
AXONH44784_064211
AXNAX27061_4661
AXXERS451415_04691(pphA_2)
ADTAPT56_21465
AISBUW96_13040
ACHRC2U31_15990
ACHBDVB37_20080
AFAUZ73_10460
AFQAFA_00195
AAQUD3M96_00180
AAMMFE795_00160
PHNPAEH1_00300
PARKLSG25_17940
AAVAave_3887
AAAAcav_2122
RDPRD2015_687
MEUACJ67_08960
AZOazo2698(pepM)
AOAdqs_2833
HCPHCN_1062
HCBHCBAA847_0912
HWIA0Z60_07480(aepX)
CJUC8J_1331
CHYOCHH_1593
CHWA2J15_004815(aepX)
CINFCINF_1344
AFCAFAEC_0069 AFAEC_0075
ANTArnit_2943
NSANitsa_1412
PCAPcar_0628
PACEA6070_12585
PPDPpro_2167
DAKDaAHT2_1860
DALDalk_1323
SCLsce7305(pepM)
SCUSCE1572_42550
LLUAKJ09_10387
MRMA7982_08317
DAODesac_2268
MLOmlr5882 mlr9115
MLNA9174_32585
MESPC1M53_20905 C1M53_20975(aepX)
MJREB229_33300(aepX)
MERDEB233_30950(aepX)
PHTBLM14_26360
SMKSinme_5760 Sinme_6918
EAKEKH55_5861
EMXFKV68_24015(aepX)
AVIAvi_3412
REPIE4803_PB00125
RTRRTCIAT899_PB01485
RJGCCGE525_35255(aepX)
AOLS58_09510
BRCBCCGELA001_29045
BICLMTR13_25005 LMTR13_25105
BGQX265_36095(aepX)
BGZXH91_35300(aepX)
BARHWN72_10290(aepX) WN72_10315
BVZBRAD3257_7243(bcpB)
RPCRPC_3871
SIWGH266_09715(aepX)
THAACFI11_00245(aepX)
RGIRGI145_09790
ROSCTJ15_07640(aepX)
RMUCFOB66_09665(aepX)
RMTIAI58_18640(aepX)
LCKHN018_01540(aepX)
SHUMSTHU_42930(pepM)
SVCSTVA_42000(pepM)
STELSTAQ_05370(pepM)
AZZDEW08_28020(aepX)
MAGXXM1_0907(pepM)
TMOTMO_b0348
ECOGFIV45_08000(aepX)
BSTOC0V70_16040(aepX)
BSSBSUW23_01000(rhiH)
BYABANAU_0589(pepM)
BQYMUS_0647
BAMBBAPNAU_0598(pepM)
BMPNG74_00659(pphA)
BACIB1NLA3E_03305
BACBOY17_06005
BITBIS30_11520
BMQBMQ_0784(aepX)
BMDBMD_0785(aepX)
BMHBMWSH_4464
BMEGBG04_3078(aepX)
PARHI5S86_23670(aepX)
PTBDER53_11735(aepX)
PCALBV455_03446(pphA)
VPTKBP50_14610
MEKUHUW50_16405(aepX)
BOUI5818_22340(aepX)
BLRBRLA_c034010
BRWGOP56_09095(aepX)
PPYPPE_04396 PPE_04791
PPOLX809_41430
PTAHPL003_06765
PLVERIC2_c18340(bcpB) ERIC2_c19750(pphA)
PIHUB51_20100 UB51_20630
PPEOABE82_25180
PKBB4V02_00175 B4V02_16725
PAIHASL14_12565
PLUTEI981_13655(aepX)
PCHIPC41400_18315(aepX)
TUMCBW65_17945
TABCIG75_00855(aepX) CIG75_11125(aepX)
EFFskT53_29670
KEBGXN75_05285(aepX)
PABSJIR001_16510
CTCCTC_01698
CTETBN906_01840
CBJH04402_02796
CBECbei_4338
CBZCbs_4338
CBEILF65_04862
CSRCspa_c46190(ppm)
CSBCLSA_c08730(ppm)
CBUTATN24_05940
CARGRSJ17_12820
CDYF3K33_22185(aepX)
CCAAKQH81_02885(aepX)
RALRumal_1340
RCHRUM_11420
CLEClole_3577
RIXRO1_19910
HASHalsa_0038
SSGSelsp_0338
SELEADJ74_04700
SELOAXE86_05255
SELTBCS37_10905
LCGL3BBH23_02720
CQNG7Y29_04590
NBRO3I_021395
NTPCRH09_19455
NOZDMB37_07995
NAHF5544_23990
SDVBN159_4099(pphA)
SALSSLNWT_1191
SCIB446_27570
STRTA8713_00495
SGSAVL59_02540 AVL59_12480 AVL59_31615
SALWCP975_03135
SVUB1H20_34190
SALFSMD44_04407(pepM)
SGDELQ87_04600(aepX)
SSPODDQ41_14920
SRIMCP984_37460(aepX)
SPHVF9278_14905
STSUB7R87_30300
SATAC5746_04685
SCHFIPT68_10945
SDWK7C20_15030
SCALI6J39_33920
SPEUCGZ69_10215
SROIIAG44_40255
SDDD9753_30290
KSKKSE_22660
KABB7C62_03680
STRIC7M71_015100
LSEF1C12_11070
RTXTI83_02260
RTCAPU90_04215
ARHAHiyo8_pI68760
CELHGXP71_14045
TESBW730_00185
SAIUJ4H86_04280(aepX)
FRAFrancci3_1533
FALFRAAL6377
AMYCCU254_05890
AMYYYIM_29505(pphA)
APRECNX65_16920
SSYIEKG83_20790
KALKALB_5539
ACTAC1701_23200(aepX)
SAQSare_1956
NHYJQS43_02325(aepX)
SNASnas_5665
NAVJQS30_13655(aepX)
ARDAXF14_02085
AYMYM304_30130
OLSOlsu_0594
ARPNIES39_A00310
MPROBJP34_15505
NEDHUN01_29215(aepX)
TOQHCG51_21875(aepX)
NCNBZZ01_05235
OBGVerru16b_03222(pphA)
TDETDE_1413
TBETrebr_0279
TAZTREAZ_2217
TPITREPR_2364
SCDSpica_1331
TPKJO40_09715
TPHGFUT81_06855(aepX)
TRIDYE50_04590(aepX)
TPAVHRQ91_06190(aepX)
SSMSpirs_4230
STASTHERM_c15610
SBUSpiBuddy_0272
SGPSpiGrapes_1560
BHCJFL75_01540(aepX)
TPXTurpa_2340
FSUFisuc_0993
FSCFSU_1439
BTHBT_1720
BTHOBtheta7330_01295(pphA)
BFRBF1832 BF2578
BFSBF9343_1814(aepX)
BFGBF638R_1867
BUNBun01g_29040
BEGINE88_02862
BSTEK6V31_00385(aepX)
BDOEL88_10435
PCOILK433_14490(aepX)
DRCG0Q07_19260(aepX)
FUVJR347_10760(aepX)
NDENIDE2903
NMVNITMOv2_0598(pepM)
NIONITINOP_0319
NJANSJP_1710
NKFNkreftii_001262
NLIG3M70_12635(aepX)
METBAW729_03845
TARTALC_00083
NMRNmar_0160
NCTNMSP_0156
NIUDSQ19_09555
PSYTDSAG12_01622(ribL_1)
ARGQT11_C0001G0509
 » show all
Reference
1
  Authors
Bowman, E., McQueney, M., Barry, R.J. and Dunaway-Mariano, D.
  Title
Catalysis and thermodynamics of the phosphoenolpyruvate phosphonopyruvate rearrangement - entry into the phosphonate class of naturally-occurring organo-phosphorus compounds.
  Journal
J Am Chem Soc 110:5575-5576 (1988)
Reference
2  [PMID:2160937]
  Authors
Hidaka T, Imai S, Hara O, Anzai H, Murakami T, Nagaoka K, Seto H
  Title
Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.
  Journal
J Bacteriol 172:3066-72 (1990)
DOI:10.1128/JB.172.6.3066-3072.1990
Reference
3  [PMID:3138545]
  Authors
Seidel HM, Freeman S, Seto H, Knowles JR
  Title
Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond.
  Journal
Nature 335:457-8 (1988)
DOI:10.1038/335457a0
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.2.9
IUBMB Enzyme Nomenclature: 5.4.2.9
ExPASy - ENZYME nomenclature database: 5.4.2.9
BRENDA, the Enzyme Database: 5.4.2.9
CAS: 115756-49-5
LinkDB

KEGG   REACTION: R00661
Entry
R00661                      Reaction                               
Name
phosphoenolpyruvate 2,3-phosphonomutase
Definition
Phosphoenolpyruvate <=> 3-Phosphonopyruvate
Equation
Reaction class
RC02792  C00074_C02798
Enzyme
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Orthology
K01841  phosphoenolpyruvate phosphomutase [EC:5.4.2.9]
K23999  phosphoenolpyruvate phosphomutase / 2-hydroxyethylphosphonate cytidylyltransferase [EC:5.4.2.9 2.7.7.104]
Other DBs
RHEA: 17016
LinkDB

DBGET integrated database retrieval system