| Entry |
|
|---|
| Symbol |
murF
|
|---|
| Name |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC: 6.3.2.10]
|
|---|
| Pathway |
|
|---|
| Reaction |
| R04573 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:alanyl-D-alanine ligase (ADP-forming) |
| R04617 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate:D-alanyl-D-alanine ligase (ADP-forming) |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
Enzymes [BR:ko01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
|
|---|
| Other DBs |
|
|---|
| Genes |
» show all
|
|---|
| Reference |
|
|---|
| Authors |
Duncan K, van Heijenoort J, Walsh CT |
|---|
| Title |
Purification and characterization of the D-alanyl-D-alanine-adding enzyme from Escherichia coli. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Anderson MS, Eveland SS, Onishi HR, Pompliano DL |
|---|
| Title |
Kinetic mechanism of the Escherichia coli UDPMurNAc-tripeptide D-alanyl-D-alanine-adding enzyme: use of a glutathione S-transferase fusion. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| LinkDB |
|
|---|
