KEGG   ORTHOLOGY: K02229
Entry
K02229                      KO                                     
Symbol
cobG
Name
precorrin-3B synthase [EC:1.14.13.83]
Pathway
map00860  Porphyrin metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00925  Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K02229  cobG; precorrin-3B synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.83  precorrin-3B synthase
     K02229  cobG; precorrin-3B synthase
Other DBs
RN: R05217
COG: COG0155
GO: 0043818
Genes
FAU: Fraau_1285
PAE: PA2906
PAEV: N297_3009(cobG)
PAEI: N296_3009(cobG)
PAU: PA14_26485
PAP: PSPA7_2248(cobG)
PAG: PLES_21581
PAF: PAM18_2056
PNC: NCGM2_4016
PAEB: NCGM1900_3405
PAEP: PA1S_10880
PAEM: U769_10420
PAEL: T223_10890
PAEG: AI22_22990
PAEC: M802_3006(cobG)
PAEO: M801_2874(cobG)
PMY: Pmen_4571
PMK: MDS_4903
PRE: PCA10_06440(cobG)
PPSE: BN5_4376(nirA)
PCQ: PcP3B5_08200(sir_1)
PMUI: G4G71_29140(cobG)
PPU: PP_4829(cobG)
PPF: Pput_4707
PPT: PPS_4673
PPI: YSA_03772
PPX: T1E_3711
PPUH: B479_23600
PPUT: L483_29295
PPUN: PP4_48990(cobG)
PPUD: DW66_5064
PMON: X969_23050
PMOT: X970_22685
PMOL: CLJ08_09710(cobG)
PSB: Psyr_4417
PSYR: N018_22885
PAMG: BKM19_025865(cobG)
PAVL: BKM03_25620(cobG)
PCAB: JGS08_23295(cobG)
PPRC: PFLCHA0_c06640(nirA)
PPRO: PPC_0668
PFE: PSF113_0640(cobG)
PFS: PFLU_0604
PFC: PflA506_0584(cobG)
PFB: VO64_3679
PMAN: OU5_2849
PRX: HRH33_03870(cobG)
PFW: PF1751_v1c05660(cobG)
PEN: PSEEN4871(cobG)
PPUU: PputUW4_00538(cobG)
PKC: PKB_0655
PSES: PSCI_2413
PSEM: TO66_03125
PSOS: POS17_0648
PANR: A7J50_0586
PSET: THL1_740
PSIL: PMA3_02495
PKE: DLD99_03375(cobG)
PALL: UYA_24325
PUM: HGP31_03285(cobG)
PPSH: G5J76_00390(cobG)
PGY: AWU82_04745(cobG)
PLAL: FXN65_03105(cobG)
PSEJ: HNQ25_01790(cobG)
PVK: EPZ47_03115(cobG)
PEZ: HWQ56_03105(cobG)
PBZ: GN234_14935(cobG)
PKH: JLK41_25070(cobG)
PTY: JWV26_09770(cobG)
PATA: JWU58_24375(cobG)
PDW: BV82_2844(cobG)
PZE: HU754_004430(cobG)
PMOE: HV782_004020(cobG)
PCAM: HNE05_10555(cobG)
PSEP: C4K39_0646
PVW: HU752_003990(cobG)
PTRT: HU722_0003925(cobG)
PXA: KSS93_04950(cobG)
PSAM: HU731_019025(cobG)
PTZ: HU718_004060(cobG)
PQI: KH389_02785(cobG)
PSHH: HU773_003725(cobG)
PXN: HU772_021985(cobG)
PHV: HU739_014510(cobG)
PPRG: HU725_020155(cobG)
PANH: HU763_021615(cobG)
PASG: KSS96_03910(cobG)
PFAK: KSS94_23975(cobG)
PMUY: KSS95_05845(cobG)
PMAM: KSS90_22505(cobG)
PAZE: KSS91_03560(cobG)
PALV: KSS97_04230(cobG)
PORY: EJA05_25140(cobG)
PWZ: J7655_00790(cobG)
PTK: EXN22_04395(cobG)
PZA: HU749_004155(cobG)
PIE: HU724_003940(cobG)
PWY: HU734_003865(cobG)
PTAE: NCTC10697_03995(sir_2)
ACX: Achr_f740(cobG)
ATEP: Atep_10670
TKM: TK90_0801
TVR: TVD_04725
NAX: HC341_18435(cobG)
HEL: HELO_1833(cobG)
HAM: HALO2053
EME: CEM_066(cobG)
BMA: BMA1161
BML: BMA10229_A0264(cobG)
BMN: BMA10247_0896(cobG)
BMAL: DM55_2997(cobG)
BMAE: DM78_1463(cobG)
BMAQ: DM76_2979(cobG)
BMAI: DM57_62
BMAF: DM51_890(cobG)
BMAZ: BM44_2182(cobG)
BMAB: BM45_1746(cobG)
BPS: BPSL1759
BPM: BURPS1710b_2113(cobG)
BPL: BURPS1106A_1967(cobG)
BPD: BURPS668_1950(cobG)
BPR: GBP346_A1991(cobG)
BPSE: BDL_283(cobG)
BPSM: BBQ_1620(cobG)
BPSU: BBN_1745(cobG)
BPSD: BBX_2220(cobG)
BPK: BBK_3245(cobG)
BPSH: DR55_2853(cobG)
BPSA: BBU_456(cobG)
BPSO: X996_2474(cobG)
BUT: X994_923(cobG)
BTE: BTH_I2398
BTJ: BTJ_834(cobG)
BTZ: BTL_2077(cobG)
BTD: BTI_2041(cobG)
BTV: BTHA_2276(cobG)
BTHE: BTN_2690(cobG)
BTHM: BTRA_2356(cobG)
BTHA: DR62_2838
BTHL: BG87_2298(cobG)
BOK: DM82_1296(cobG)
BOC: BG90_3396(cobG)
BSAV: WS86_09650
BVE: AK36_2237(cobG)
BCN: Bcen_1194
BCJ: BCAL1726
BCEN: DM39_1638(cobG)
BCEW: DM40_2297(cobG)
BCEO: I35_1639
BAM: Bamb_1574
BMJ: BMULJ_01676(cobG)
BMU: Bmul_1568
BMK: DM80_3324(cobG)
BMUL: NP80_1764(cobG)
BCT: GEM_1742
BCED: DM42_23(cobG)
BDL: AK34_1437(cobG)
BCON: NL30_14715
BUB: BW23_49(cobG)
BLAT: WK25_08190
BTEI: WS51_18885
BSEM: WJ12_08285
BPSL: WS57_26840
BMEC: WJ16_08390
BSTG: WT74_08620
BANN: JFN94_08485(cobG)
BGU: KS03_2696(cobG)
BGO: BM43_3281(cobG)
BUL: BW21_2106(cobG)
BGP: BGL_1c18550(cobG)
BURK: DM992_12750(cobG)
BXE: Bxe_B1245
BXB: DR64_6560(cobG)
BPH: Bphy_3143
BFN: OI25_6988(cobG)
PSPW: BJG93_26325(cobG)
PARB: CJU94_22965(cobG)
PHS: C2L64_26525(cobG)
PTER: C2L65_21860(cobG)
PGP: CUJ91_23005(cobG)
PCJ: CUJ87_21940(cobG)
PTS: CUJ90_30150(cobG)
PMEG: FNZ07_10885(cobG)
PTRO: G5S35_18505(cobG)
PACP: FAZ97_16460(cobG)
PACS: FAZ98_21025(cobG)
PEW: KZJ38_31275(cobG)
PLG: NCTC10937_00830(sir_1)
CABA: SBC2_64800(sir_2)
RHG: EXZ61_08075(cobG)
PVAC: HC248_02556(sir_2)
DAC: Daci_5851
DLA: I6G47_26405(cobG)
CTES: O987_11765
DRG: H9K76_03160(cobG)
MLO: mlr1378
MESP: C1M53_23855(cobG)
MHUA: MCHK_2983(cobG)
MJR: EB229_19425(cobG)
MERD: EB233_16785(cobG)
MESR: FGU64_05690(cobG)
AMIH: CO731_02904(sir_2)
NIY: FQ775_15235(cobG)
NKI: KW403_18460(cobG)
SME: SMc03193(cobG)
SMX: SM11_chr3096(cobG)
SMI: BN406_02780(cobG)
SMEL: SM2011_c03193(cobG)
SMER: DU99_16110
SMD: Smed_2818
RHI: NGR_c29810(cobG)
SFH: SFHH103_02988(cobG)
SFD: USDA257_c53970(cobG)
SIX: BSY16_3269(cobG)
SAME: SAMCFNEI73_Ch3353(cobG)
EAD: OV14_0449(cobG)
EMX: FKV68_18425(cobG)
ATU: Atu2803(cobG)
ARA: Arad_9596(cobG)
AGR: AGROH133_09256(cobG)
ATF: Ach5_26870(cobG)
ARO: B0909_26060(cobG)
AGT: EYD00_12105(cobG)
ALF: CFBP5473_01375(cobG)
ARUI: G6M88_07430(cobG)
RET: RHE_PE00455(cobG)
REC: RHECIAT_PA0000378(cobG)
REL: REMIM1_PD00478(cobG)
REP: IE4803_PA00414(cobG)
REI: IE4771_PC00427(cobG)
RLE: pRL110631(cobG)
RLG: Rleg_7174
RTR: RTCIAT899_PC06990(cobG)
RIR: BN877_I2891(cobG)
RPUS: CFBP5875_12435(cobG)
RHL: LPU83_pLPU83d0187(cobG)
RGA: RGR602_PC01216(cobG)
RHN: AMJ98_PD00464(cobG)
RPHA: AMC79_PB00387(cobG)
RHX: AMK02_PE00471(cobG)
RHK: Kim5_PB00447(cobG)
REZ: AMJ99_PC00465(cobG)
RHR: CKA34_23615(cobG)
RGR: FZ934_26145(cobG)
RAD: CO657_32030(cobG)
RII: FFM53_030970(cobG)
RHID: FFM81_030445(cobG)
RBQ: J2J99_29215(cobG)
RLN: J0663_26685(cobG)
RBAN: J2J98_26060(cobG)
RRG: J3P73_31270(cobG)
RLS: HB780_04980(cobG)
NEO: CYG48_18570(cobG)
NEN: NCHU2750_36450(cobG)
RHT: NT26_3123(cobG)
SHZ: shn_19590
SZO: K8M09_16570(cobG)
BME: BMEI0715
BMEL: DK63_712(cobG)
BMI: BMEA_A1333(cobG)
BMZ: BM28_A1297(cobG)
BMEE: DK62_142(cobG)
BMF: BAB1_1304
BABO: DK55_1281(cobG)
BABR: DO74_609(cobG)
BABT: DK49_1038(cobG)
BABB: DK48_839(cobG)
BABU: DK53_1265(cobG)
BABS: DK51_195(cobG)
BABC: DO78_1186(cobG)
BMS: BR1286
BSUI: BSSP1_I0407(cobG)
BSUP: BSPT1_I0414(cobG)
BSUV: BSPT2_I0409(cobG)
BSUC: BSSP2_I1312(cobG)
BMT: BSUIS_A1336(cobG)
BSZ: DK67_1012(cobG)
BOV: BOV_1249(cobG)
BCS: BCAN_A1309(cobG)
BCAR: DK60_1325(cobG)
BCAS: DA85_06170
BMR: BMI_I1299(cobG)
BPP: BPI_I1338(cobG)
BPV: DK65_94(cobG)
BVL: BF3285c1_2096(cobG)
OIN: IAR37_10335(cobG)
BIO: BR141012304_11411(cobG)
OAN: Oant_1899
OAH: DR92_1387(cobG)
OCH: CES85_1434(cobG)
OCR: HGK82_06925(cobG)
OCL: GTN27_07280(cobG)
BJA: blr3264(blr3264)
BRA: BRADO4906
BBT: BBta_3145
BRS: S23_47400
AOL: S58_27840(cobG)
BRAD: BF49_1434
BRO: BRAD285_2330(cobG)
BRK: CWS35_19605(cobG)
BOT: CIT37_37240(cobG)
BRQ: CIT40_10805(cobG)
BGQ: X265_24800(cobG)
BGZ: XH91_22840(cobG)
BSYM: CIT39_09785(cobG)
BBET: F8237_03830(cobG)
BARH: WN72_17830(cobG)
BDG: LPJ38_19135(cobG)
BSEP: HAP48_0032360(cobG)
BQB: J4P68_0033630(cobG)
TRB: HB776_31190(cobG)
BOS: BSY19_876(cobG)
BOF: FQV39_16505(cobG)
XAU: Xaut_3285
XDI: EZH22_26145(cobG)
AZC: AZC_3936(cobG)
SNO: Snov_2570
STAR: G3545_27485(cobG)
LNE: FZC33_26080(cobG)
ANC: GBB76_07570(cobG)
APRA: G3A50_04340(cobG)
MEA: Mex_1p1327(cobG)
MDI: METDI2099(cobG)
MEX: Mext_1438
MCH: Mchl_1713
MPO: Mpop_1435
MET: M446_2439
MNO: Mnod_2150
MOR: MOC_3496
META: Y590_06690
MAQU: Maq22A_c09430(cysI)
METD: C0214_08165(cobG)
METS: DK389_14515(cobG)
METI: DK427_20890(cobG)
MMES: MMSR116_15305(cobG)
MIND: mvi_30700
BID: Bind_3508
MSL: Msil_3267
MLG: CWB41_06655(cobG)
HDN: Hden_2698
MCG: GL4_0404
METG: HT051_12415(cobG)
PHL: KKY_929
DEI: C4375_01915(cobG)
DEA: FPZ08_01600(cobG)
DSAL: K1X15_04470(cobG)
YTI: FNA67_00845(cobG)
MSC: BN69_3121
MROS: EHO51_03285(cobG)
MHEY: H2LOC_005970(cobG)
CMET: K6K41_25930(cobG)
HDI: HDIA_3058(cobG)
PSTG: E8M01_31140(cobG)
LIZ: LGH83_01535(cobG)
SIL: SPO2864
JAN: Jann_2930
RDE: RD1_3826(cobG)
RLI: RLO149_c006180(cobG)
RPON: G3256_12355(cobG)
PGD: Gal_02676
PHQ: D1820_17190(cobG)
LEJ: ETW24_14090(cobG)
LAQU: R2C4_04845(cobG)
CID: P73_0491
MALG: MALG_01209
SULZ: C1J03_01430(cobG)
SPOT: G6548_14650(cobG)
SMED: JNX03_14245(cobG)
MALU: KU6B_33100
PDE: Pden_2533
PZH: CX676_19960(cobG)
PARO: CUV01_00705(cobG)
PARR: EOJ32_02925(cobG)
PKD: F8A10_01375(cobG)
PSAN: HGN31_15800(cobG)
GFU: KM031_03280(cobG)
TAW: EI545_12780(cobG)
SEDI: EBB79_05435(cobG)
POZ: I0K15_06400(cobG)
CACT: HZ995_01200(cobG)
NAR: Saro_0341
SPHP: LH20_21945
STAX: MC45_16195
SECH: B18_27490
SJP: SJA_C2-03100(cobG)
SINB: SIDU_11835
SPMI: K663_18391
SPHB: EP837_03434(cobG)
SPHT: K426_22459
GOH: B932_2913
GTI: FXF46_12985(cobG)
GFA: MKW11_13510(cobG)
AMV: ACMV_P1_00620(cobG)
GXY: GLX_19990
GXL: H845_2986
KEU: S101446_02477(cobG)
KRE: GWK63_00935(cobG)
APT: APA01_14560(cobG)
APW: APA42C_14560(cobG)
APF: APA03_14560(cobG)
APU: APA07_14560(cobG)
APG: APA12_14560(cobG)
APQ: APA22_14560(cobG)
APX: APA26_14560(cobG)
APZ: APA32_14560(cobG)
APK: APA386B_318(CobG)
ASZ: ASN_3532(cobG)
ATO: CIW82_13855(cobG)
AOY: EOV40_006720(cobG)
ROS: CTJ15_10580(cobG)
RMUC: FOB66_08890(cobG)
RMT: IAI58_02695(cobG)
KHA: IFJ82_00085(cobG)
AZL: AZL_d03290(cobG)
ALI: AZOLI_p40247(cobG)
AZT: TSH58p_24040(cobG)
AZM: DM194_24375(cobG)
AZZ: DEW08_00445(cobG)
AOZ: HUE56_04790(cobG)
NAO: Y958_29295(cobG)
PARH: I5S86_25800(cobG)
MTU: Rv2064(cobG)
MTV: RVBD_2064
MTC: MT2124
MRA: MRA_2078(cobG)
MTUR: CFBS_2185(cobG)
MTO: MTCTRI2_2102(cobG)
MTD: UDA_2064(cobG)
MTN: ERDMAN_2279(cobG)
MTUE: J114_11050
MTUH: I917_14550
MTUL: TBHG_02022
MTUT: HKBT1_2179(cobG)
MTUU: HKBT2_2180(cobG)
MTQ: HKBS1_2184(cobG)
MBO: BQ2027_MB2090(cobG)
MBB: BCG_2083(cobG)
MBT: JTY_2077(cobG)
MBM: BCGMEX_2067(cobG)
MAF: MAF_20790(cobG)
MMIC: RN08_2288
MCE: MCAN_20871(cobG)
MCQ: BN44_40356(cobG)
MCV: BN43_31257(cobG)
MCX: BN42_30375(cobG)
MCZ: BN45_50371(cobG)
MPA: MAP_1810(cobG)
MAO: MAP4_2018
MAVI: RC58_10055
MAVU: RE97_10065
MIT: OCO_24280
MIA: OCU_24150
MID: MIP_03355
MYO: OEM_22730
MIR: OCQ_22820
MMAL: CKJ54_11005(cobG)
MMAN: MMAN_15390(cobG)
MUL: MUL_2288
MMC: Mmcs_2489
MKM: Mkms_2534
MJL: Mjls_2526
MMI: MMAR_3044
MMM: W7S_11715
MHAD: B586_10815
MSHG: MSG_02946(cobG)
MFJ: MFLOJ_02720(cobG)
MSTO: MSTO_03400(cobG)
MSIM: MSIM_47560(cobG)
MSAK: MSAS_10200(cobG)
MKU: I2456_15035(cobG)
MGRO: FZ046_21610(cobG)
MNV: MNVI_43120(cobG)
MPAG: C0J29_17400(cobG)
MGOR: H0P51_16405(cobG)
MSEO: MSEO_17620(cobG)
MPSE: MPSD_31590(cobG)
MSHO: MSHO_44080(cobG)
MGAU: MGALJ_14600(cobG)
MLJ: MLAC_20500(cobG)
MBRD: MBRA_37360(cobG)
MKR: MKOR_06780(cobG)
MDF: K0O62_14590(cobG)
MMAM: K3U93_13775(cobG)
MHOL: K3U96_11635(cobG)
MSEN: K3U95_14905(cobG)
MPAE: K0O64_14140(cobG)
MSPG: F6B93_12985(cobG)
MOT: LTS72_09200(cobG)
MSM: MSMEG_3871(cobG)
MSG: MSMEI_3781(cobG)
MVA: Mvan_3429
MGI: Mflv_3106
MFT: XA26_35740(cobG)
MVQ: MYVA_3340
MHAS: MHAS_01629
MDU: MDUV_10740(cobG)
MCHT: MCHIJ_39990(cobG)
MDR: MDOR_17490(cobG)
MMAG: MMAD_33050(cobG)
MMOR: MMOR_35640(cobG)
MFX: MFAL_11360(cobG)
MAIC: MAIC_25780(cobG)
MIJ: MINS_29710(cobG)
MALV: MALV_04180(cobG)
MTY: MTOK_53300(cobG)
MPSC: MPSYJ_32790(cobG)
MARZ: MARA_06390(cobG)
MGAD: MGAD_10200(cobG)
MHEV: MHEL_57130(cobG)
MSAR: MSAR_42080(cobG)
MANY: MANY_16940(cobG)
MAUB: MAUB_11100(cobG)
MPOF: MPOR_36030(cobG)
MPHU: MPHO_02200(cobG)
MMUC: C1S78_017340(cobG)
MMAT: MMAGJ_70700(cobG)
MBOK: MBOE_38450(cobG)
MFG: K6L26_14425(cobG)
MSEI: MSEDJ_45300(cobG)
MAB: MAB_2200c
MABB: MASS_2127
MCHE: BB28_11065
MSTE: MSTE_02139
MSAL: DSM43276_01913(sir_2)
MMIN: MMIN_08460
ASD: AS9A_2041
MPAK: MIU77_07670(cobG)
CGL: Cgl1482(Cgl1482)
CGB: cg1677(cobG)
CGU: WA5_1427
CGT: cgR_1544
CGM: cgp_1677
CGJ: AR0_07950
CEF: CE1610
CDI: DIP1231
CDIP: ERS451417_01231(cobG)
CAR: cauri_1273(cobG)
CKP: ckrop_0898(cobG)
CPL: Cp3995_1043(cobG)
CPP: CpP54B96_1039(cobG)
CPZ: CpPAT10_1019(cobG)
COR: Cp267_1068(cobG)
COD: Cp106_1002(cobG)
COS: Cp4202_1012(cobG)
CPSE: CPTA_01591
CPSU: CPTB_02173
CPSF: CPTC_01581
CUL: CULC22_01094(cobG)
CUC: CULC809_01079(cobG)
CUE: CULC0102_1201(cobG)
CUN: Cul210932_1133(cobG)
CUS: CulFRC11_1103(cobG)
CUQ: Cul210931_1085(cobG)
CUZ: Cul05146_1159(cobG)
CUJ: CUL131002_1117(cobG)
COA: DR71_80(cobG)
CMV: CMUST_07935(cobG)
CSP: WM42_0083
CPHO: CPHO_06140
CAMG: CAMM_06675
CMIN: NCTC10288_01251(cobG)
CRL: NCTC7448_01901(cobG)
CSUR: N24_1575
NFA: NFA_31400
NCY: NOCYR_3312(cobG)
NSR: NS506_05033(cobG)
NTP: CRH09_17450(cobG)
NOD: FOH10_12535(cobG)
NAH: F5544_26280(cobG)
NWL: NWFMUON74_32400(cobG)
NTC: KHQ06_26025(cobG)
NHU: H0264_20995(cobG)
NYA: LTV02_13065(cobG)
NGP: LTT66_27310(cobG)
RER: RER_31420(cobG)
REY: O5Y_14425
RQI: C1M55_15675(cobG)
ROP: ROP_02920(cobG)
REQ: REQ_23580(cobG)
RHB: NY08_990
RCR: NCTC10994_00420(cobG_1) NCTC10994_03359(cobG_2)
RTM: G4H71_21725(cobG)
RKO: JWS14_01525(cobG)
RGO: KYT97_04430(cobG)
GBR: Gbro_2481
GPO: GPOL_c24150(cobG)
GOR: KTR9_2390
GOC: CXX93_12410(cobG)
GIT: C6V83_11340(cobG)
GJI: H1R19_11930(cobG)
TPR: Tpau_2192
SALB: XNR_4668
SGR: SGR_3824
SGB: WQO_16615
SCB: SCAB_9781(cobG)
SFA: Sfla_3029
SBH: SBI_01765
SVE: SVEN_3517
STRP: F750_3737(cobG)
SFI: SFUL_3820
SALU: DC74_4103
SALL: SAZ_21870
STRE: GZL_04792
SLD: T261_4279
STRM: M444_26935
SPRI: SPRI_5139
SKY: D0C37_25160(cobG)
SGM: GCM10017557_05120(cobG)
SLAU: SLA_3556
SALJ: SMD11_0881(cobG)
SLX: SLAV_09390(sir1)
SFK: KY5_6082
SGZ: C0216_09500(cobG)
SPAD: DVK44_12790(cobG)
SRIM: CP984_20355(cobG)
SSUB: CP968_07840(cobG)
SPHV: F9278_42925(cobG)
SCOE: CP976_34785(cobG)
SSPB: CP982_23085(cobG)
SDW: K7C20_18415(cobG)
SAUH: SU9_016570(cobG)
SPRA: CP972_32435(cobG)
SPEU: CGZ69_10605(cobG)
SANU: K7396_18330(cobG)
KSK: KSE_64810(cobG)
LMOI: VV02_21340
MPH: MLP_03490(cobG)
NDK: I601_3837
PSIM: KR76_17040
KFL: Kfla_5082
KQI: F1D05_07860(cobG)
TFU: Tfu_0318
NDA: Ndas_1626
NAL: B005_0636
SAIU: J4H86_16740(cobG)
SRO: Sros_5592
NGN: LCN96_34155(cobG)
TBI: Tbis_2494
FAL: FRAAL2331(cobG)
NML: Namu_0151
NAK: EH165_13560(cobG)
GOB: Gobs_0576
BSD: BLASA_1265(cobG)
MMAR: MODMU_0657(cobG)
SEN: SACE_5953
AMD: AMED_7063(cobG)
AMN: RAM_36240
AMM: AMES_6955(cobG)
AMZ: B737_6955(cobG)
AOI: AORI_1667(cobG)
AMQ: AMETH_5466(cobG)
AMYY: YIM_35550
AORI: SD37_32815
PDX: Psed_3022
PSEA: WY02_28250
PSEH: XF36_14705
PAUT: Pdca_27100(cobG)
AMI: Amir_1783
SESP: BN6_25830
ALO: CRK57394
SACE: GIY23_16885(cobG)
MIL: ML5_4312
MSAG: GCM10017556_51970(cobG)
ASE: ACPL_6899(cobG)
ACTN: L083_6534
AFS: AFR_33980
ACTS: ACWT_6768
PFLA: Pflav_005720(cobG)
AEY: CDG81_07520(cobG)
ABAS: ACPOL_5051
 » show all
LinkDB

KEGG   ENZYME: 1.14.13.83
Entry
EC 1.14.13.83               Enzyme                                 
Name
precorrin-3B synthase;
precorrin-3X synthase;
CobG
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)
Reaction(IUBMB)
precorrin-3A + NADH + H+ + O2 = precorrin-3B + NAD+ + H2O [RN:R05217]
Reaction(KEGG)
R05217
Substrate
precorrin 3A [CPD:C05772];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
precorrin 3B [CPD:C06406];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively.
History
EC 1.14.13.83 created 2004
Pathway
ec00860  Porphyrin metabolism
ec01100  Metabolic pathways
Orthology
K02229  precorrin-3B synthase
Genes
FAUFraau_1285
PAEPA2906
PAEVN297_3009(cobG)
PAEIN296_3009(cobG)
PAUPA14_26485
PAPPSPA7_2248(cobG)
PAGPLES_21581
PAFPAM18_2056
PNCNCGM2_4016
PAEBNCGM1900_3405
PDKPADK2_09840
PSGG655_10275
PRPM062_15560
PAEPPA1S_10880
PAERPA1R_gp0738
PAEMU769_10420
PAELT223_10890
PAESSCV20265_2200
PAEUBN889_03247
PAEGAI22_22990
PAECM802_3006(cobG)
PAEOM801_2874(cobG)
PMYPmen_4571
PMKMDS_4903
PREPCA10_06440(cobG)
PPSEBN5_4376(nirA)
PFUWKF707C_6080
PALCA0T30_08810
PCQPcP3B5_08200(sir_1)
PMUIG4G71_29140(cobG)
PPUPP_4829(cobG)
PPFPput_4707
PPGPputGB1_4885
PPWPputW619_4619
PPTPPS_4673
PPBPPUBIRD1_4616
PPIYSA_03772
PPXT1E_3711
PPUHB479_23600
PPUTL483_29295
PPUNPP4_48990(cobG)
PPUDDW66_5064
PFVPsefu_0056
PMONX969_23050
PMOTX970_22685
PMOSO165_019890
PPJRK21_05706
PORAPT59_19365
PMOLCLJ08_09710(cobG)
PSTPSPTO_4877
PSBPsyr_4417
PSYRN018_22885
PSPPSPPH_4460
PSAVPSA3335_24105
PAMGBKM19_025865(cobG)
PCIPCH70_46870
PAVLBKM03_25620(cobG)
PVDCFBP1590_0854
PCABJGS08_23295(cobG)
PPRCPFLCHA0_c06640(nirA)
PPROPPC_0668
PFEPSF113_0640(cobG)
PFNHZ99_21050
PFOPfl01_0604
PFSPFLU_0604
PFCPflA506_0584(cobG)
PPZH045_23810
PFBVO64_3679
PMANOU5_2849
PTVAA957_11050
PCGAXG94_18305
PVRPverR02_03040
PAZOAYR47_10205
POIBOP93_02840
PRXHRH33_03870(cobG)
PFWPF1751_v1c05660(cobG)
PFFPFLUOLIPICF705350
PFXA7318_02040
PENPSEEN4871(cobG)
PBAPSEBR_a616
PBCCD58_03200
PPUUPputUW4_00538(cobG)
PDRH681_03015
PSVPVLB_03055
PSKU771_03445
PKCPKB_0655
PCHEY04_02590
PCZPCL1606_54390
PCPJM49_27125
PFZAV641_20390
PLQAA042_13085
PALKPSAKL28_47320
PRHLT40_13760
PSWLK03_08485
PSESPSCI_2413
PSEMTO66_03125
PSECCCOS191_0654
PPSYAOC04_17730
PSOSPOS17_0648
PKRAYO71_05800
PFKPFAS1_08105
PANRA7J50_0586
PPSLBJP27_11325
PSETTHL1_740
PSILPMA3_02495
PYMAK972_5306
PKEDLD99_03375(cobG)
PALLUYA_24325
PUMHGP31_03285(cobG)
POJPtoMrB4_08050
PGGFX982_02095
PPSHG5J76_00390(cobG)
PGYAWU82_04745(cobG)
PLALFXN65_03105(cobG)
PSEJHNQ25_01790(cobG)
PVKEPZ47_03115(cobG)
PEZHWQ56_03105(cobG)
PBZGN234_14935(cobG)
PKHJLK41_25070(cobG)
PTYJWV26_09770(cobG)
PATAJWU58_24375(cobG)
PDWBV82_2844(cobG)
PZEHU754_004430(cobG)
PMOEHV782_004020(cobG)
PCAMHNE05_10555(cobG)
PSEPC4K39_0646
PVWHU752_003990(cobG)
PTRTHU722_0003925(cobG)
PXAKSS93_04950(cobG)
PSAMHU731_019025(cobG)
PTZHU718_004060(cobG)
PQIKH389_02785(cobG)
PSHHHU773_003725(cobG)
PXNHU772_021985(cobG)
PHVHU739_014510(cobG)
PPRGHU725_020155(cobG)
PANHHU763_021615(cobG)
PASGKSS96_03910(cobG)
PFAKKSS94_23975(cobG)
PMUYKSS95_05845(cobG)
PMAMKSS90_22505(cobG)
PAZEKSS91_03560(cobG)
PALVKSS97_04230(cobG)
PORYEJA05_25140(cobG)
PWZJ7655_00790(cobG)
PTKEXN22_04395(cobG)
PTWTUM18999_08440
PZAHU749_004155(cobG)
PIEHU724_003940(cobG)
PWYHU734_003865(cobG)
PTAENCTC10697_03995(sir_2)
ACXAchr_f740(cobG)
SPOIIMCC21906_00670
ATEPAtep_10670
TKMTK90_0801
TVRTVD_04725
NAXHC341_18435(cobG)
GAIIMCC3135_08930
HELHELO_1833(cobG)
HCSFF32_13125
HAMHALO2053
HHUAR456_06995
HALOBWR19_06610
HALKCUU95_17020
HVNEI420_07535
HSRHSBAA_38990
HTTHZS52_14805
HSVHNO53_14315
HTXEKK97_15440
EMECEM_066(cobG)
ZPLZBT109_0851
HAAA5892_05020
KUSB9G99_08975
KMAB9H00_05880
KUYFY550_01095
BMABMA1161
BMVBMASAVP1_A1602
BMLBMA10229_A0264(cobG)
BMNBMA10247_0896(cobG)
BMALDM55_2997(cobG)
BMAEDM78_1463(cobG)
BMAQDM76_2979(cobG)
BMAIDM57_62
BMAFDM51_890(cobG)
BMAZBM44_2182(cobG)
BMABBM45_1746(cobG)
BPSBPSL1759
BPMBURPS1710b_2113(cobG)
BPLBURPS1106A_1967(cobG)
BPDBURPS668_1950(cobG)
BPRGBP346_A1991(cobG)
BPSEBDL_283(cobG)
BPSMBBQ_1620(cobG)
BPSUBBN_1745(cobG)
BPSDBBX_2220(cobG)
BPZBP1026B_I1716
BPQBPC006_I2019
BPKBBK_3245(cobG)
BPSHDR55_2853(cobG)
BPSABBU_456(cobG)
BPSOX996_2474(cobG)
BUTX994_923(cobG)
BTEBTH_I2398
BTJBTJ_834(cobG)
BTZBTL_2077(cobG)
BTDBTI_2041(cobG)
BTVBTHA_2276(cobG)
BTHEBTN_2690(cobG)
BTHMBTRA_2356(cobG)
BTHADR62_2838
BTHLBG87_2298(cobG)
BOKDM82_1296(cobG)
BOCBG90_3396(cobG)
BUUWS70_08280
BSAVWS86_09650
BVIBcep1808_1610
BVEAK36_2237(cobG)
BURBcep18194_A4824
BCNBcen_1194
BCHBcen2424_1674
BCMBcenmc03_1647
BCJBCAL1726
BCENDM39_1638(cobG)
BCEWDM40_2297(cobG)
BCEOI35_1639
BAMBamb_1574
BACBamMC406_1592
BMJBMULJ_01676(cobG)
BMUBmul_1568
BMKDM80_3324(cobG)
BMULNP80_1764(cobG)
BCTGEM_1742
BCEDDM42_23(cobG)
BCEPAPZ15_12965
BDLAK34_1437(cobG)
BPYRABD05_14235
BCONNL30_14715
BUBBW23_49(cobG)
BDFWI26_07970
BLATWK25_08190
BTEIWS51_18885
BSEMWJ12_08285
BPSLWS57_26840
BMECWJ16_08390
BSTGWT74_08620
BSTLBBJ41_03680
BANNJFN94_08485(cobG)
BGLbglu_1g18430
BGUKS03_2696(cobG)
BUGBC1001_3690
BGFBC1003_3739
BGDbgla_1g19420
BGOBM43_3281(cobG)
BYIBYI23_B004130
BUEBRPE67_BCDS06740
BULBW21_2106(cobG)
BUQAC233_20425
BGPBGL_1c18550(cobG)
BPLAbpln_1g17210
BUDAQ610_09895
BUMAXG89_17270
BUIAX768_26990
BURKDM992_12750(cobG)
BXEBxe_B1245
BXBDR64_6560(cobG)
BPHBphy_3143
BGEBC1002_3952
BPXBUPH_00257
BPYBphyt_5369
BUZAYM40_27190
BFNOI25_6988(cobG)
BCAIK788_0002807
PSPWBJG93_26325(cobG)
PARABTO02_29900
PARBCJU94_22965(cobG)
PHSC2L64_26525(cobG)
PTERC2L65_21860(cobG)
PGPCUJ91_23005(cobG)
PCJCUJ87_21940(cobG)
PTSCUJ90_30150(cobG)
PMEGFNZ07_10885(cobG)
PTROG5S35_18505(cobG)
PGISI6I06_23405
PACPFAZ97_16460(cobG)
PACSFAZ98_21025(cobG)
PEWKZJ38_31275(cobG)
PVEUC34_18570
PFGAB870_05585
PLGNCTC10937_00830(sir_1)
CABASBC2_64800(sir_2)
BUOBRPE64_BCDS09080
RSBRS694_10900
RACRA876_02080
RHYRD110_04640
RHGEXZ61_08075(cobG)
PVACHC248_02556(sir_2)
AANTHUK68_04400
DACDaci_5851
DELDelCs14_0748
DTSBI380_25835
DHKBO996_27435
DLAI6G47_26405(cobG)
CTTCtCNB1_1878
CTESO987_11765
CSERCCO03_13770
CAQTKAQ61_16485
DIHG7047_04435
DAERH9K75_21135
DRGH9K76_03160(cobG)
TTWLCC91_06120
RBHB4966_14485
ZPAC3497_13825
MLOmlr1378
MLNA9174_19130
MCIMesci_3279
MOPMesop_3675
MAMMesau_03550
MAMOA6B35_22275
MESWA9K65_017750
MESPC1M53_23855(cobG)
MHUAMCHK_2983(cobG)
MJREB229_19425(cobG)
MERDEB233_16785(cobG)
MESRFGU64_05690(cobG)
MESOBSQ44_06490
AAKAA2016_2922
AMIHCO731_02904(sir_2)
PHTBLM14_01750
NIYFQ775_15235(cobG)
NKIKW403_18460(cobG)
SMESMc03193(cobG)
SMKSinme_2978
SMQSinmeB_2753
SMXSM11_chr3096(cobG)
SMIBN406_02780(cobG)
SMEGC770_GR4Chr3053
SMELSM2011_c03193(cobG)
SMERDU99_16110
SMDSmed_2818
RHINGR_c29810(cobG)
SFHSFHH103_02988(cobG)
SFDUSDA257_c53970(cobG)
SIXBSY16_3269(cobG)
SAMESAMCFNEI73_Ch3353(cobG)
SINOSS05631_c27800
EADOV14_0449(cobG)
EAHFA04_15860
ESJSJ05684_c29390
EAKEKH55_2876
EMXFKV68_18425(cobG)
ATUAtu2803(cobG)
ARAArad_9596(cobG)
ATAAWN88_18875
AGRAGROH133_09256(cobG)
ATFAch5_26870(cobG)
AROB0909_26060(cobG)
AGTEYD00_12105(cobG)
ALFCFBP5473_01375(cobG)
ARUIG6M88_07430(cobG)
RETRHE_PE00455(cobG)
RECRHECIAT_PA0000378(cobG)
RELREMIM1_PD00478(cobG)
REPIE4803_PA00414(cobG)
REIIE4771_PC00427(cobG)
RLEpRL110631(cobG)
RLTRleg2_6019
RLGRleg_7174
RLBRLEG3_05755
RLURLEG12_01460
RTRRTCIAT899_PC06990(cobG)
RIRBN877_I2891(cobG)
RPUSCFBP5875_12435(cobG)
RHLLPU83_pLPU83d0187(cobG)
RGARGR602_PC01216(cobG)
RHNAMJ98_PD00464(cobG)
RPHAAMC79_PB00387(cobG)
RHXAMK02_PE00471(cobG)
RHVBA939_08590
RHKKim5_PB00447(cobG)
REZAMJ99_PC00465(cobG)
RHRCKA34_23615(cobG)
RGRFZ934_26145(cobG)
RADCO657_32030(cobG)
RIIFFM53_030970(cobG)
RHIDFFM81_030445(cobG)
RBQJ2J99_29215(cobG)
RLNJ0663_26685(cobG)
RBANJ2J98_26060(cobG)
RRGJ3P73_31270(cobG)
RLSHB780_04980(cobG)
NGLRG1141_CH39000
NGGRG540_CH39560
NEOCYG48_18570(cobG)
NENNCHU2750_36450(cobG)
RHTNT26_3123(cobG)
RFVRFYW14_03155
SHZshn_19590
SZOK8M09_16570(cobG)
BMEBMEI0715
BMELDK63_712(cobG)
BMIBMEA_A1333(cobG)
BMZBM28_A1297(cobG)
BMGBM590_A1288
BMWBMNI_I1247
BMEEDK62_142(cobG)
BMFBAB1_1304
BMBBruAb1_1287
BMCBAbS19_I12170
BAABAA13334_I01930
BABODK55_1281(cobG)
BABRDO74_609(cobG)
BABTDK49_1038(cobG)
BABBDK48_839(cobG)
BABUDK53_1265(cobG)
BABSDK51_195(cobG)
BABCDO78_1186(cobG)
BMSBR1286
BSIBS1330_I1282
BSFBSS2_I1253
BSUIBSSP1_I0407(cobG)
BSUPBSPT1_I0414(cobG)
BSUVBSPT2_I0409(cobG)
BSUCBSSP2_I1312(cobG)
BMTBSUIS_A1336(cobG)
BSZDK67_1012(cobG)
BSVBSVBI22_A1282
BSWIY71_06365
BSGIY72_06105
BOVBOV_1249(cobG)
BCSBCAN_A1309(cobG)
BSKBCA52141_I3131
BOLBCOUA_I1286
BCARDK60_1325(cobG)
BCASDA85_06170
BMRBMI_I1299(cobG)
BPPBPI_I1338(cobG)
BPVDK65_94(cobG)
BCETV910_100710
BVLBF3285c1_2096(cobG)
BRUBFS01_06215
BRJBKD03_15705
OINIAR37_10335(cobG)
BIOBR141012304_11411(cobG)
OANOant_1899
OAHDR92_1387(cobG)
OPSA8A54_06055
OCHCES85_1434(cobG)
OCRHGK82_06925(cobG)
OCLGTN27_07280(cobG)
BJAblr3264(blr3264)
BJUBJ6T_64860
BJPRN69_31440
BRABRADO4906
BBTBBta_3145
BRSS23_47400
AOLS58_27840(cobG)
BRCBCCGELA001_14695
BRADBF49_1434
BICLMTR13_27130
BROBRAD285_2330(cobG)
BRKCWS35_19605(cobG)
BOTCIT37_37240(cobG)
BRQCIT40_10805(cobG)
BGQX265_24800(cobG)
BGZXH91_22840(cobG)
BSYMCIT39_09785(cobG)
BBETF8237_03830(cobG)
BARHWN72_17830(cobG)
BVZBRAD3257_5436
BELBE61_67570
BDGLPJ38_19135(cobG)
BSEPHAP48_0032360(cobG)
BQBJ4P68_0033630(cobG)
TRBHB776_31190(cobG)
BOPAXW83_22085
BOSBSY19_876(cobG)
BVVBHK69_09280
BOIBLM15_18780
BOFFQV39_16505(cobG)
BAPIBBC0122_010760
XAUXaut_3285
XDIEZH22_26145(cobG)
AZCAZC_3936(cobG)
SNOSnov_2570
STARG3545_27485(cobG)
LNEFZC33_26080(cobG)
ANCGBB76_07570(cobG)
APRAG3A50_04340(cobG)
MEAMex_1p1327(cobG)
MDIMETDI2099(cobG)
MEXMext_1438
MCHMchl_1713
MPOMpop_1435
MZAB2G69_14820
MRDMrad2831_3116
METM446_2439
MNOMnod_2150
MORMOC_3496
METAY590_06690
MAQUMaq22A_c09430(cysI)
MPHYMCBMB27_02529
MEEDA075_09565
METDC0214_08165(cobG)
METXA3862_16370
METSDK389_14515(cobG)
METIDK427_20890(cobG)
MMESMMSR116_15305(cobG)
MTEADK419_17315
MINDmvi_30700
MOGMMB17_11150
MOCBB934_23010
BIDBind_3508
MSLMsil_3267
MTUNMTUNDRAET4_2074
MLGCWB41_06655(cobG)
CDQBOQ54_02600
HDNHden_2698
HDTHYPDE_37128
HMCHYPMC_0688
HNIW911_07195
FILBN1229_v1_3175
FIYBN1229_v1_2747
RHZRHPLAN_54940
MCGGL4_0404
METGHT051_12415(cobG)
NTDEGO55_18800
PHLKKY_929
DEQXM25_19535
DEIC4375_01915(cobG)
DEAFPZ08_01600(cobG)
DSALK1X15_04470(cobG)
YTIFNA67_00845(cobG)
MSCBN69_3121
MBRYB1812_19490
MROSEHO51_03285(cobG)
MHEYH2LOC_005970(cobG)
MPARF7D14_00510
MTWCQW49_09585
CMETK6K41_25930(cobG)
PLEOOHA_1_04104
HDIHDIA_3058(cobG)
PPHRAPZ00_04930
PSTGE8M01_31140(cobG)
LIZLGH83_01535(cobG)
SILSPO2864
SITTM1040_2211
RUAD1823_08505
RUTFIU92_04780
JANJann_2930
RDERD1_3826(cobG)
RLIRLO149_c006180(cobG)
RPONG3256_12355(cobG)
PGAPGA1_c08160
PGLPGA2_c07940
PGDGal_02676
PHPPhaeoP97_00783
PPICPhaeoP14_00738
PHQD1820_17190(cobG)
LMDMETH_04270
LEJETW24_14090(cobG)
LAQUR2C4_04845(cobG)
REDroselon_02158
CIDP73_0491
MALGMALG_01209
CONTQ29_16325
YPACCEW88_21515
TPROGa0080559_TMP4823
PABYGa0080574_TMP1466
SUAMBOO69_17215
SULZC1J03_01430(cobG)
SULDB5M07_16155
SPOTG6548_14650(cobG)
SMEDJNX03_14245(cobG)
SINLDSM14862_03172
SPSESULPSESMR1_02789
TOMBWR18_10950
ROHFIU89_17340
AHTANTHELSMS3_02546
THAACFI11_03885
MARUFIU81_15670
MALUKU6B_33100
RHPLPB142_02380
PDEPden_2533
PYEA6J80_00325
PCONB0A89_04425
PZHCX676_19960(cobG)
PAROCUV01_00705(cobG)
PARREOJ32_02925(cobG)
PKDF8A10_01375(cobG)
PPANESD82_11585
PSANHGN31_15800(cobG)
PMAUCP157_03003
RMBK529_002805
DAAAKL17_0065
RBGBG454_16755
GEHHYN69_05150 HYN69_19270(cobG) HYN69_20080(cobG)
GFUKM031_03280(cobG)
TAWEI545_12780(cobG)
SALOEF888_09255
SEDIEBB79_05435(cobG)
HMLHmaOT1_14750
BOOE2K80_13835
PSEBEOK75_19675
MONG8E03_05170
POZI0K15_06400(cobG)
CACTHZ995_01200(cobG)
GCEKYE46_07720
NARSaro_0341
NPPPP1Y_AT19816
NPNJI59_17205
NREBES08_17755
NOVTQ38_023150
NORFA702_01405
SPHPLH20_21945
STAXMC45_16195
SPANAWL63_14940
SPLKAV944_15490
SPHAD3Y57_03095
SPAUDRN02_016880
SECHB18_27490
SJPSJA_C2-03100(cobG)
SINBSIDU_11835
SCHSphch_3765
SYBTZ53_06715
SBDATN00_04670
SPMIK663_18391
SPHBEP837_03434(cobG)
SPHTK426_22459
SYAA6768_25040
SBARH5V43_18255
SPPHKFK14_09690
GOHB932_2913
GTIFXF46_12985(cobG)
GFAMKW11_13510(cobG)
GBEGbCGDNIH1_0659
GBHGbCGDNIH2_0659
GBCGbCGDNIH3_0659
GBSGbCGDNIH4_0659
AMVACMV_P1_00620(cobG)
GXYGLX_19990
GXLH845_2986
KNAB0W47_10045
KEUS101446_02477(cobG)
KSCCD178_00945
KREGWK63_00935(cobG)
APTAPA01_14560(cobG)
APWAPA42C_14560(cobG)
APFAPA03_14560(cobG)
APUAPA07_14560(cobG)
APGAPA12_14560(cobG)
APQAPA22_14560(cobG)
APXAPA26_14560(cobG)
APZAPA32_14560(cobG)
APKAPA386B_318(CobG)
ASZASN_3532(cobG)
ASVWG31_07665
APERA0U91_12270
APOMCPF11_12885
ATOCIW82_13855(cobG)
AASCA4S02_05315
ACETDS739_07545
AOTAcetOri_orf04576
AOYEOV40_006720(cobG)
ACEKFLP30_11370
ABGAsbog_02404
KBAA0U89_06140
RGIRGI145_06850
ROSCTJ15_10580(cobG)
RMUCFOB66_08890(cobG)
RMTIAI58_02695(cobG)
COQD9V35_07645
COMMGN303_07435
SSAME3D00_09365
EBLAJGUZn3_06450
LCKHN018_05935
KHAIFJ82_00085(cobG)
AZLAZL_d03290(cobG)
ALIAZOLI_p40247(cobG)
ABSAZOBR_p140032
ABQABAZ39_19900
ABFAMK58_14940
ATIAL072_25330
AZTTSH58p_24040(cobG)
AZMDM194_24375(cobG)
AZZDEW08_00445(cobG)
AOZHUE56_04790(cobG)
NAOY958_29295(cobG)
PARHI5S86_25800(cobG)
MTURv2064(cobG)
MTVRVBD_2064
MTCMT2124
MRAMRA_2078(cobG)
MTFTBFG_12100
MTBTBMG_01917
MTKTBSG_01930
MTZTBXG_001902
MTIMRGA423_12855
MTECCDC5079_1909
MTURCFBS_2185(cobG)
MTLCCDC5180_1885
MTOMTCTRI2_2102(cobG)
MTDUDA_2064(cobG)
MTNERDMAN_2279(cobG)
MTJJ112_11050
MTUBMT7199_2095
MTUEJ114_11050
MTXM943_10700
MTUHI917_14550
MTULTBHG_02022
MTUTHKBT1_2179(cobG)
MTUUHKBT2_2180(cobG)
MTQHKBS1_2184(cobG)
MBOBQ2027_MB2090(cobG)
MBBBCG_2083(cobG)
MBTJTY_2077(cobG)
MBMBCGMEX_2067(cobG)
MBKK60_021440
MAFMAF_20790(cobG)
MMICRN08_2288
MCEMCAN_20871(cobG)
MCQBN44_40356(cobG)
MCVBN43_31257(cobG)
MCXBN42_30375(cobG)
MCZBN45_50371(cobG)
MPAMAP_1810(cobG)
MAOMAP4_2018
MAVIRC58_10055
MAVURE97_10065
MITOCO_24280
MIAOCU_24150
MIDMIP_03355
MYOOEM_22730
MCHIAN480_12220
MIROCQ_22820
MMALCKJ54_11005(cobG)
MMANMMAN_15390(cobG)
MSAMycsm_03710
MULMUL_2288
MMCMmcs_2489
MKMMkms_2534
MJLMjls_2526
MMIMMAR_3044
MMAEMMARE11_29670
MMMW7S_11715
MLIMULP_02766
MKNMKAN_01820
MYVG155_17530
MYEAB431_14750
MGOAFA91_20705
MHADB586_10815
MDXBTO20_14165
MSHGMSG_02946(cobG)
MFJMFLOJ_02720(cobG)
MSTOMSTO_03400(cobG)
MSIMMSIM_47560(cobG)
MSAKMSAS_10200(cobG)
MKUI2456_15035(cobG)
MGROFZ046_21610(cobG)
MXEMYXE_23500
MNVMNVI_43120(cobG)
MPAGC0J29_17400(cobG)
MNMMNVM_29090
MGORH0P51_16405(cobG)
MBAIMB901379_02823
MSEOMSEO_17620(cobG)
MPSEMPSD_31590(cobG)
MSHOMSHO_44080(cobG)
MHEKJMUB5695_02277
MGAUMGALJ_14600(cobG)
MLJMLAC_20500(cobG)
MBRDMBRA_37360(cobG)
MKRMKOR_06780(cobG)
MDFK0O62_14590(cobG)
MMAMK3U93_13775(cobG)
MHOLK3U96_11635(cobG)
MHERK3U94_17805
MSENK3U95_14905(cobG)
MPAEK0O64_14140(cobG)
MSPGF6B93_12985(cobG)
MOTLTS72_09200(cobG)
MSMMSMEG_3871(cobG)
MSGMSMEI_3781(cobG)
MSBLJ00_19230
MSNLI99_19235
MSHLI98_19240
MVAMvan_3429
MGIMflv_3106
MSPMspyr1_24220
MCBMycch_3059
MNED174_14400
MYNMyAD_14145
MFTXA26_35740(cobG)
MPHLMPHLCCUG_02697
MVQMYVA_3340
MLLB1R94_11820
MRHMycrhN_5081
MTHN4412656_01959
MHASMHAS_01629
MDUMDUV_10740(cobG)
MCHTMCHIJ_39990(cobG)
MDRMDOR_17490(cobG)
MAUUNCTC10437_03304
MMAGMMAD_33050(cobG)
MMORMMOR_35640(cobG)
MFXMFAL_11360(cobG)
MAICMAIC_25780(cobG)
MIJMINS_29710(cobG)
MALVMALV_04180(cobG)
MTYMTOK_53300(cobG)
MPSCMPSYJ_32790(cobG)
MARZMARA_06390(cobG)
MGADMGAD_10200(cobG)
MHEVMHEL_57130(cobG)
MSARMSAR_42080(cobG)
MANYMANY_16940(cobG)
MAUBMAUB_11100(cobG)
MPOFMPOR_36030(cobG)
MPHUMPHO_02200(cobG)
MMUCC1S78_017340(cobG)
MMATMMAGJ_70700(cobG)
MBOKMBOE_38450(cobG)
MFGK6L26_14425(cobG)
MSEIMSEDJ_45300(cobG)
MFLVNCTC10271_02124
MABMAB_2200c
MMVMYCMA_1171
MABBMASS_2127
MABLMMASJCM_2151
MCHEBB28_11065
MIZBAB75_11785
MSTEMSTE_02139
MSAOMYCSP_09445
MSALDSM43276_01913(sir_2)
MJDJDM601_3162
MTER4434518_03148
MMINMMIN_08460
ASDAS9A_2041
MPAKMIU77_07670(cobG)
CGLCgl1482(Cgl1482)
CGBcg1677(cobG)
CGUWA5_1427
CGTcgR_1544
CGSC624_08210
CGGC629_08220
CGMcgp_1677
CGJAR0_07950
CGQCGLAR1_07815
CGXSB89_07655
CEFCE1610
CDIDIP1231
CDPCD241_1161
CDHCDB402_1140
CDTCDHC01_1160
CDECDHC02_1139
CDRCDHC03_1134
CDACDHC04_1144
CDZCD31A_1242
CDBCDBH8_1209
CDSCDC7B_1225
CDDCDCE8392_1132
CDWCDPW8_1210
CDVCDVA01_1101
CDIPERS451417_01231(cobG)
CARcauri_1273(cobG)
CKPckrop_0898(cobG)
CPUCPFRC_05150
CPLCp3995_1043(cobG)
CPGCP316_05300
CPPCpP54B96_1039(cobG)
CPKCP1002_07995
CPQCPC231_05155
CPXCPI19_06365
CPZCpPAT10_1019(cobG)
CORCp267_1068(cobG)
COPCP31_05530
CODCp106_1002(cobG)
COSCp4202_1012(cobG)
COICPCIP5297_05320
COECP258_05315
COUCP162_05975
CPSECPTA_01591
CPSUCPTB_02173
CPSFCPTC_01581
CULCULC22_01094(cobG)
CUCCULC809_01079(cobG)
CUECULC0102_1201(cobG)
CUNCul210932_1133(cobG)
CUSCulFRC11_1103(cobG)
CUQCul210931_1085(cobG)
CUZCul05146_1159(cobG)
CUJCUL131002_1117(cobG)
CHNA605_07270
CCNH924_06805
CAZCARG_04700
CCGCCASEI_07170
CVTB843_06965
COADR71_80(cobG)
CDOCDOO_07265
CSXCSING_07005
CMQB840_06220
CKUUL82_05110
CCJUL81_05950
CMVCMUST_07935(cobG)
CEICEPID_06300
CUTCUTER_05385
CLWCLAC_06560
CSPWM42_0083
CSTACSTAT_06475
CCJZccrud_07190
CPHOCPHO_06140
CFCCFLV_06295
CSTRCBE89_07150
CAMGCAMM_06675
CMINNCTC10288_01251(cobG)
CPEGCPELA_05640
CXEFOB82_12515
CEECENDO_05720
CGKCGERO_05495
CRFFRC0190_01206
CRLNCTC7448_01901(cobG)
CCHOCCHOA_05745
CPSOCPPEL_05840
CSURN24_1575
CMATHBA49_00210
CYZC3B44_05715
CKFI6I12_06765
CGLUI6J20_03785
CLIZG7Y31_05795
CSILCBE74_06170
CTUBI6I74_11045
CKWCKALI_05540
CCOECETAM_06615
COKCOCCU_07220
CORYFQV43_05025
CMFGWO64_006235
BFVC628_08150
NFANFA_31400
NFRERS450000_00933
NCYNOCYR_3312(cobG)
NBRO3I_026630
NNONONO_c34280
NSLBOX37_11665
NSRNS506_05033(cobG)
NTPCRH09_17450(cobG)
NOZDMB37_05560
NODFOH10_12535(cobG)
NAHF5544_26280(cobG)
NADNCTC11293_04427
NWLNWFMUON74_32400(cobG)
NIEKV110_25860
NTCKHQ06_26025(cobG)
NHUH0264_20995(cobG)
NYALTV02_13065(cobG)
NGPLTT66_27310(cobG)
RHARHA1_ro00172
RERRER_31420(cobG)
REYO5Y_14425
REBXU06_14645
RQIC1M55_15675(cobG)
ROPROP_02920(cobG)
ROAPd630_LPD04183
REQREQ_23580(cobG)
RPYY013_04170 Y013_10495 Y013_14615
RBYCEJ39_15005 CEJ39_21285
RHBNY08_990
RAVAAT18_13870 AAT18_20425
RFAA3L23_04241
RHSA3Q41_04025
RHWBFN03_08205
RRZCS378_03575 CS378_09895
RHUA3Q40_01746
RHQIM25_02235 IM25_18375
RHODAOT96_25875
RRT4535765_02673 4535765_03940(cobG)
RCRNCTC10994_00420(cobG_1) NCTC10994_03359(cobG_2)
RTMG4H71_21725(cobG)
RKOJWS14_01525(cobG)
RGOKYT97_04430(cobG)
GBRGbro_2481
GPOGPOL_c24150(cobG)
GORKTR9_2390
GOQACH46_17885
GTABCM27_12745
GOCCXX93_12410(cobG)
GITC6V83_11340(cobG)
GRUGCWB2_12930
GOMD7316_01022
GAVC5O27_15160
GODGKZ92_11690
GAMGII34_11665
GPDGII33_10965
GJIH1R19_11930(cobG)
GOILK459_21315
SPINKV203_09600
TPRTpau_2192
TSMASU32_11930
DTMBJL86_1611
DITC3V38_13645
DIZCT688_01015 CT688_07820
DPCA6048_01055 A6048_08075
DLUA6035_07670 A6035_16375
TOYFO059_08560
SALBXNR_4668
SGRSGR_3824
SGBWQO_16615
SCBSCAB_9781(cobG)
SSXSACTE_3451
SVLStrvi_3782
SSOII1A49_39265
SCTSCAT_p1407
SCYSCATT_p03190
SFASfla_3029
SBHSBI_01765
SVESVEN_3517
STRPF750_3737(cobG)
SFISFUL_3820
SALUDC74_4103
SALLSAZ_21870
STREGZL_04792
SLDT261_4279
SLCSL103_00580
STRMM444_26935
SPRISPRI_5139
SCZABE83_17215
STRFASR50_31645
SRNA4G23_02852
SPAVSpa2297_00580
SCLFBB341_15530
SKYD0C37_25160(cobG)
SALWCP975_27580
SGMGCM10017557_05120(cobG)
SNRSNOUR_21795
SAUOBV401_39135
SSIAA7J05_09215
SVUB1H20_18020
SGVB1H19_20645
SLAUSLA_3556
SALJSMD11_0881(cobG)
SLXSLAV_09390(sir1)
STROSTRMOE7_19265
SFKKY5_6082
SQZFQU76_27715
STIRDDW44_05010
SKACP970_10550
SGZC0216_09500(cobG)
SVNCP980_07115
SNKCP967_16360
SRKFGW37_27670
SFICEIZ62_15590
SSPODDQ41_16635
SVRCP971_05305
SPADDVK44_12790(cobG)
SCAVCVT27_17285
SRIMCP984_20355(cobG)
SSUBCP968_07840(cobG)
SPHVF9278_42925(cobG)
SCINCP977_16855
STSUB7R87_28090
SGXH4W23_19590
SCOECP976_34785(cobG)
SBATG4Z16_18410
SSPBCP982_23085(cobG)
SNFJYK04_06550
SPLACP981_19045
SHUNDWB77_04052
SLIAHA039_14190
SDWK7C20_18415(cobG)
SCALI6J39_18030
SAUHSU9_016570(cobG)
SFBCP974_15450
SMOBJ7W19_28820
SPRACP972_32435(cobG)
SPEUCGZ69_10605(cobG)
SXNIAG42_18455
SGJIAG43_09225
SHKJ2N69_28540
SANUK7396_18330(cobG)
KSKKSE_64810(cobG)
KABB7C62_18155
KAUB6264_00710
KITCFP65_6480
DNIHX89_07905
DAYFV141_07120
LMOIVV02_21340
ALXLVQ62_02010
ICAIntca_0797
JTEASJ30_05380
JLIEXU32_09405
JMEEEW87_16655
TEHGKE56_09795
SERWFY030_12825
DCOSAMEA4475696_1933
ARUBJ5A65_09170
MPHMLP_03490(cobG)
TEZBKM78_01685
RAINRai3103_07665 Rai3103_07675
PRVG7070_09055
NCANoca_2894 Noca_3411
NDKI601_3837
NSNEXE58_16720
NBEBack2_05030
NANOG5V58_13465
NAROCFH99_15685
NPIG7071_10065
NAQUENKNEFLB_00281(sir_1) ENKNEFLB_01628
NROK8W59_16035
PSIMKR76_17040
AERAERYTH_14665
AEZC3E78_16200
KFLKfla_5082
KQIF1D05_07860(cobG)
TFUTfu_0318
THAONI17_022110
NDANdas_1626
NALB005_0636
SAIUJ4H86_16740(cobG)
AGRAAGRA3207_000946
SROSros_5592
NOABKM31_07275
NGNLCN96_34155(cobG)
TBITbis_2494
FRAFrancci3_1519
FRIFraEuI1c_0479
FALFRAAL2331(cobG)
NMLNamu_0151
NAKEH165_13560(cobG)
GOBGobs_0576
BSDBLASA_1265(cobG)
MMARMODMU_0657(cobG)
SENSACE_5953
SVISvir_17650
AMDAMED_7063(cobG)
AMNRAM_36240
AMMAMES_6955(cobG)
AMZB737_6955(cobG)
AOIAORI_1667(cobG)
AJAAJAP_31135
AMQAMETH_5466(cobG)
AMYCCU254_28595
AMYBBKN51_00560
AABA4R43_41500
AMYYYIM_35550
AORISD37_32815
AACDLWP59_31880
PDXPsed_3022
PSEAWY02_28250
PSEHXF36_14705
PHHAFB00_23130
PAUTPdca_27100(cobG)
APRECNX65_08890
AMIAmir_1783
SESPBN6_25830
SSYIEKG83_11655
KPHYAOZ06_33695
LEDBBK82_26175
ALOCRK57394
PMADBAY61_06060
SACEGIY23_16885(cobG)
MILML5_4312
MTUACSH63_04880
MSAGGCM10017556_51970(cobG)
MCRAID554_29965
ASEACPL_6899(cobG)
AMSAMIS_66360
ACTNL083_6534
AFSAFR_33980
ACTSACWT_6768
AIHAiant_27450
PLABC6361_08330
PLATC6W10_04895
PFLAPflav_005720(cobG)
PSUUPsuf_062590
VERHUT12_15090
DVCDvina_13500
NHYJQS43_13765
AEYCDG81_07520(cobG)
EKEEK0264_07655
BSOLFSW04_05180
ACMAciX9_3945
GMAAciX8_1795
ABASACPOL_5051
 » show all
Reference
1  [PMID:8226690]
  Authors
Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F
  Title
Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans.
  Journal
J Bacteriol 175:7430-40 (1993)
DOI:10.1128/JB.175.22.7430-7440.1993
Reference
2  [PMID:8405386]
  Authors
Scott AI, Roessner CA, Stolowich NJ, Spencer JB, Min C, Ozaki SI.
  Title
Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group.
  Journal
FEBS Lett 331:105-8 (1993)
DOI:10.1016/0014-5793(93)80306-F
Reference
3  [PMID:12195810]
  Authors
Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC.
  Title
The biosynthesis of adenosylcobalamin (vitamin B12).
  Journal
Nat Prod Rep 19:390-412 (2002)
DOI:10.1039/b108967f
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.83
IUBMB Enzyme Nomenclature: 1.14.13.83
ExPASy - ENZYME nomenclature database: 1.14.13.83
BRENDA, the Enzyme Database: 1.14.13.83
CAS: 152787-63-8
LinkDB

KEGG   REACTION: R05217
Entry
R05217                      Reaction                               
Name
precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)
Definition
Precorrin 3A + Oxygen + NADH + H+ <=> Precorrin 3B + NAD+ + H2O
Equation
Comment
oxidoreduction, CobG, [Fe-S]
Reaction class
RC00001  C00003_C00004
RC01979  C05772_C06406
Enzyme
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00925  Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
Orthology
K02229  precorrin-3B synthase [EC:1.14.13.83]
Other DBs
RHEA: 17296
LinkDB

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