KEGG   ORTHOLOGY: K02366
Entry
K02366                      KO                                     
Symbol
EXT1
Name
glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]
Pathway
map00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
map01100  Metabolic pathways
Module
M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone
Reaction
R05935  
R10138  
R10139  
Disease
H00122  Multiple exostoses
H00493  Heparan sulfate proteoglycan gene defects
H00977  Trichorhinophalangeal syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.224  glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
     K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
    2.4.1.225  N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
     K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1
Other DBs
GO: 0050508 0050509
CAZy: GT47 GT64
Genes
HSA: 2131(EXT1)
PTR: 107976420(EXT1)
PPS: 100985695(EXT1)
GGO: 109025298(EXT1)
PON: 100172450(EXT1)
PPYG: 129041970(EXT1)
NLE: 100597702(EXT1)
HMH: 116813541(EXT1)
SSYN: 129486743(EXT1)
MCC: 701488(EXT1)
MCF: 101926231(EXT1)
MTHB: 126961556
MNI: 105468540(EXT1)
CSAB: 103237338(EXT1)
CATY: 105584539(EXT1)
TGE: 112629920(EXT1)
MLEU: 105529083
RRO: 104658897(EXT1)
RBB: 108536176(EXT1)
TFN: 117079472(EXT1)
PTEH: 111551020(EXT1)
CANG: 105511053(EXT1)
CJC: 100386964(EXT1)
SBQ: 101053444(EXT1)
CIMI: 108305915(EXT1)
ANAN: 105710789(EXT1)
CSYR: 103263660
MMUR: 105863703(EXT1)
LCAT: 123645168(EXT1)
PCOQ: 105812176(EXT1)
OGA: 100943601(EXT1)
MMU: 14042(Ext1)
MCAL: 110310432(Ext1)
MPAH: 110334870(Ext1)
RNO: 299907(Ext1)
MCOC: 116082489(Ext1)
MUN: 110559447(Ext1)
CGE: 100689334(Ext1)
MAUA: 101826524(Ext1)
PROB: 127235391(Ext1)
PLEU: 114694845(Ext1)
MORG: 121461166(Ext1)
MFOT: 126491860
AAMP: 119822782(Ext1)
NGI: 103738135(Ext1)
HGL: 101706257(Ext1)
CPOC: 100716132(Ext1)
CCAN: 109702003
DORD: 105997725(Ext1)
DSP: 122102360(Ext1)
PLOP: 125360972(Ext1)
NCAR: 124981119
MMMA: 107142875(Ext1)
OCU: 100351235
OPI: 101535829(EXT1)
TUP: 102467803(EXT1)
GVR: 103591115(EXT1)
CFA: 482024(EXT1)
CLUD: 112662087(EXT1)
VVP: 112915941(EXT1)
VLG: 121498758(EXT1)
NPO: 129502436(EXT1)
AML: 100465258(EXT1)
UMR: 103661582(EXT1)
UAH: 113252791(EXT1)
UAR: 123797768(EXT1)
ELK: 111146555
LLV: 125097162
MPUF: 101691546(EXT1)
MNP: 132014249(EXT1)
MLK: 131826469(EXT1)
NVS: 122904351(EXT1)
ORO: 101382133(EXT1)
EJU: 114199089(EXT1)
ZCA: 113931105(EXT1)
MLX: 118015150(EXT1)
NSU: 110579220(EXT1)
LWW: 102741200(EXT1)
FCA: 101081362(EXT1)
PYU: 121042894(EXT1)
PCOO: 112859477(EXT1)
PBG: 122495739(EXT1)
PVIV: 125156370(EXT1)
LRUF: 124507771
PTG: 102968916(EXT1)
PPAD: 109273237(EXT1)
PUC: 125924455
AJU: 106975536
HHV: 120228668(EXT1)
BTA: 538602(EXT1)
BOM: 102280308(EXT1)
BIU: 109568471(EXT1)
BBUB: 102407802(EXT1)
BBIS: 105005436(EXT1)
CHX: 102182809(EXT1)
OAS: 101114877(EXT1)
BTAX: 128059226(EXT1)
ODA: 120860718 120878901(EXT1)
CCAD: 122450981(EXT1)
MREE: 136144866(EXT1)
MBEZ: 129559842(EXT1)
SSC: 100157655(EXT1)
CFR: 102508456(EXT1)
CBAI: 105082972(EXT1)
CDK: 105096148(EXT1)
VPC: 102535018(EXT1)
BACU: 103019432(EXT1)
BMUS: 118883288(EXT1)
LVE: 103078738(EXT1)
OOR: 101286251(EXT1)
DLE: 111165183(EXT1)
PCAD: 102980097(EXT1)
PSIU: 116742524(EXT1)
NASI: 112397180(EXT1)
ECB: 100056983(EXT1)
EPZ: 103549478(EXT1)
EAI: 106839736(EXT1)
MYB: 102244714(EXT1)
MYD: 102765321(EXT1)
MMYO: 118670761(EXT1)
MLF: 102441376(EXT1)
MDT: 132219587(EXT1)
PKL: 118718227(EXT1)
EFUS: 103287659(EXT1)
MNA: 107533185(EXT1)
DRO: 112315333(EXT1)
SHON: 118988619(EXT1)
AJM: 119051826(EXT1)
PDIC: 114514407(EXT1)
PHAS: 123833269(EXT1)
MMF: 118631561(EXT1)
PPAM: 129084291(EXT1)
HAI: 109382533
RFQ: 117033795(EXT1)
PALE: 102891150(EXT1)
PGIG: 120595391(EXT1)
PVP: 105292239(EXT1)
RAY: 107507149(EXT1)
MJV: 108399086(EXT1)
TOD: 119238592(EXT1)
SARA: 101538625(EXT1)
SETR: 126009054(EXT1)
LAV: 100657623(EXT1)
TMU: 101362012
ETF: 101661672(EXT1)
DNM: 101436351(EXT1)
MDO: 100025396(EXT1)
GAS: 123241026(EXTL1) 123241182(EXT1)
SHR: 100929895(EXT1)
PCW: 110200303(EXT1)
TVP: 118837393(EXTL1) 118851574(EXT1)
PBRV: 138154242(EXTL1) 138155837(EXT1)
OAA: 100078206(EXT1)
GGA: 100858205(EXT1) 100859367(EXTL1)
PCOC: 116227694(EXT1) 116230047(EXTL1)
MGP: 100542119(EXT1) 100551486(EXTL1)
CJO: 107310492(EXT1) 107324063(EXTL1)
TPAI: 128088342(EXTL1) 128090880(EXT1)
LMUT: 125691409(EXT1) 125703958(EXTL1)
NMEL: 110387476(EXTL1) 110395119(EXT1)
APLA: 101792373(EXT1) 119713596(EXTL1)
ACYG: 106037911(EXTL1) 106038456(EXT1)
CATA: 118252659(EXT1) 118255759(EXTL1)
AFUL: 116485915(EXT1) 116498028(EXTL1)
TGU: 100227900(EXT1) 115498288(EXTL1)
LSR: 110472893(EXTL1) 110479282(EXT1)
SCAN: 103814231(EXT1) 103823579(EXTL1)
PMOA: 120505159(EXT1) 120513889(EXTL1)
OTC: 121337462(EXT1) 121342741(EXTL1)
PRUF: 121351215(EXTL1) 121355356(EXT1)
GFR: 102035022(EXTL1) 102043948(EXT1)
FAB: 101816822(EXT1) 101818678(EXTL1)
OMA: 130249178(EXT1) 130262245(EXTL1)
PHI: 102099981(EXT1) 102111356(EXTL1)
PMAJ: 107200137(EXT1) 107213996(EXTL1)
CCAE: 111925064(EXT1)
CCW: 104692676(EXT1)
CBRC: 103616910(EXTL1) 103623522(EXT1)
ETL: 114057979(EXT1) 114070342(EXTL1)
ZAB: 102067827(EXT1)
ZLE: 135444634(EXT1) 135457261(EXTL1)
ACHL: 103805479(EXT1)
SVG: 106849477(EXT1) 106861906(EXTL1)
MMEA: 130574552(EXT1) 130583292(EXTL1)
HRT: 120758554(EXT1) 120763137(EXTL1)
SATI: 136371154(EXTL1) 136371196(EXT1)
FPG: 101919384(EXT1) 101922176(EXTL1)
FCH: 102049940(EXT1) 102056866(EXTL1)
CCRI: 104162814(EXT1)
NNT: 104403804(EXT1)
SHAB: 115609772(EXT1) 115615978(EXTL1)
ACUN: 113476897(EXT1) 113488189(EXTL1)
TALA: 104365235(EXT1) 116964263(EXTL1)
ACHC: 115340329(EXT1) 115351760(EXTL1)
HLE: 104837180(EXTL1) 104837692(EXT1)
LDI: 104349538(EXT1)
DPUB: 104297238(EXT1) 104307496(EXTL1)
PPUS: 135181208(EXT1) 135190941(EXTL1)
AVIT: 104279093(EXT1)
BRHI: 104496894(EXT1)
EGZ: 104123693(EXT1) 104134955(EXTL1)
NNI: 104017847(EXTL1) 104018021(EXT1)
PCRI: 104037444
PCAO: 104049419
PADL: 103914958(EXT1)
AFOR: 103896426(EXTL1) 103897223(EXT1)
FGA: 104080655(EXT1)
CLV: 102084082(EXTL1) 102091811(EXT1)
MUI: 104542233 104542281(EXTL1)
PLET: 104618170
EHS: 104510203(EXT1)
CMAC: 104481663
CUCA: 104061521(EXTL1) 104066187(EXT1)
TEO: 104372233
BREG: 104641383(EXT1)
OHA: 104332486(EXT1)
CPEA: 104386715(EXT1) 104394116(EXTL1)
CVF: 104282894(EXT1) 104283937(EXTL1)
RTD: 128904733(EXT1) 128919015(EXTL1)
AROW: 112960952(EXT1) 112964418(EXTL1) 112972955
NPD: 112948502(EXT1) 112950897(EXTL1)
TGT: 104573294
DNE: 112982032(EXTL1) 112989149(EXT1)
SCAM: 104150074(EXT1)
ASN: 102370729(EXT1) 102376854(EXTL1)
AMJ: 102560415(EXT1) 102575942(EXTL1)
CPOO: 109318544(EXTL1) 109321481(EXT1)
GGN: 109294162(EXTL1) 109299004(EXT1)
PSS: 102444477(EXT1)
CMY: 102929859(EXTL1) 102939595(EXT1)
CCAY: 125624786(EXTL1) 125632784(EXT1) 125634923
DCC: 119845550(EXTL1) 119852082(EXT1) 119852576
CPIC: 101946173(EXT1) 101953823(EXTL1) 103307378
TST: 117868243(EXTL1) 117873767(EXT1)
CABI: 116818811(EXT1) 116837997(EXTL1)
MRV: 120389310(EXTL1) 120398808(EXT1)
ACS: 100553800(extl1) 100567014(ext1)
ASAO: 132775071(EXT1) 132780719(EXTL1)
PVT: 110076972(EXT1) 110084159(EXTL1)
SUND: 121915625(EXTL1) 121928875(EXT1)
PMUR: 107292260 107295666(EXTL1)
CTIG: 120307392(EXT1) 120314310(EXTL1)
TSR: 106538947 106539688(EXTL1)
PGUT: 117663388(EXTL1) 117668371(EXT1)
APRI: 131196014(EXT1) 131204188(EXTL1)
PTEX: 113437525(EXTL1) 113438272(EXT1)
NSS: 113417566(EXTL1) 113427134(EXT1)
VKO: 123019173(EXT1) 123025901(EXTL1)
PMUA: 114601312(EXT1) 114601546(EXTL1)
PRAF: 128417122(EXT1) 128418730(EXTL1)
ZVI: 118086449(EXTL1) 118089708(EXT1)
HCG: 128323737(EXT1) 128333382(EXTL1)
GJA: 107110827(EXTL1) 107113379
STOW: 125434955(EXTL1) 125439498(EXT1)
EMC: 129333222(EXT1) 129343175(EXTL1)
XLA: 398214(ext1.L) 399115(ext1.S)
XTR: 448393(ext1)
NPR: 108790563(EXT1)
RTEM: 120941479(EXT1)
BBUF: 121001066(EXT1)
BGAR: 122938154(EXT1)
MUO: 115464768 115479964(EXT1) 115480317(EXTL1)
GSH: 117355075(EXT1) 117357489 117365871(EXTL1)
DRE: 101885478 497279(ext1a) 497280(ext1b) 497281(ext1c)
LROH: 127178446(ext1a) 127181513(ext1b) 127181899(ext1c) 127182637
PPRM: 120469966(ext1c) 120479262(ext1b) 120491188(ext1a) 120493730
RKG: 130078411(ext1a) 130096027
MAMB: 125243241(ext1a) 125275117(ext1b) 125275126 125278978
CERY: 137001981 137018674 137037540(ext1b) 137037953(ext1a)
TROS: 130551302 130557989(ext1a) 130566509(ext1b) 130566756
MANU: 129448753(ext1a) 129454424(ext1b) 129454464
SMEO: 124375785(ext1b) 124375938 124401370 124403868(ext1a)
TFD: 113643961(ext1c) 113649722(ext1a) 113654795 113661608(ext1b)
AMEX: 103026919 103031914(ext1b) 103040053(ext1a) 103047171
CMAO: 118798675(ext1a) 118805664(ext1b) 118805672 118815270
CHAR: 105891959 105897019 105904948(ext1b) 105909063(ext1c)
TBEN: 117477648(ext1b) 117477663(ext1c) 117480396 117486878
SLUC: 116035281 116047237(ext1c) 116047249(ext1b) 116066120
CLUM: 117727284 117738620(ext1c) 117739586(ext1b) 117745311
CANA: 137784405(ext1c) 137784486(ext1b) 137785399 137799549
ASTR: 137601901 137607673(ext1c) 137607811(ext1b) 137613916
OML: 112143494 112162700(ext1b) 112162739(ext1c)
CSAI: 133418595 133426387 133460500(ext1c) 133461261(ext1b)
PPRL: 129354190(ext1b) 129367500 129375284 129375722(ext1c)
CTUL: 119772289(ext1c) 119775297 119777081 119778046(ext1b)
PTAO: 133468229 133470740(ext1b) 133471083(ext1c) 133479328
BSPL: 114843138 114849466 114865978(ext1b) 114866303(ext1c)
LCM: 102353460(EXT1) 102354369 102354854(EXTL1)
BFO: 118404100
BBEL: 109479557
CIN: 100185120
SCLV: 120335452
SPU: 577995
APLC: 110986223
ARUN: 117301143
AJC: 117122002
SKO: 100313593
DME: Dmel_CG10117(ttv)
DER: 6549168
DSE: 6609157
DSI: Dsimw501_GD11060(Dsim_GD11060)
DAN: 6496091
DSR: 110177800
DPO: 4803961
DPE: 6590872
DWI: 6640835
DGR: 6561214
DAZ: 108615817
DHE: 111602550
DVI: 6624746
CCAT: 101460876
BOD: 106617537
BDR: 105228120
RZE: 108363084
AOQ: 129246422
MDE: 101894872
SCAC: 106091369
LCQ: 111677307
LSQ: 119614574
GFS: 119642516
ECOE: 129940208
CLON: 129608535
HIS: 119655721
AGA: 1272657
ACOZ: 120956752
AARA: 120901724
AMER: 121599408
ASTE: 118503312
AFUN: 125768269
AMOU: 128297376
AALI: 118467462
AAG: 5578353
ASUA: 134225952
CPII: 120429091
CNS: 116340037
BCOO: 119078978
LLL: 129785989
PPAP: 129798673
AME: 408293
ACER: 107999513
ALAB: 122711993
ADR: 102678944
AFLR: 100871709
BIM: 100741317
BBIF: 117214192
BVK: 117232255
BVAN: 117156137
BHUN: 126866545
BTER: 100650849
BAFF: 126925000
BPYO: 122571366
BPAS: 132908765
FVI: 122528253
CCAL: 108627221
OLG: 117607017
MGEN: 117220187
NMEA: 116432549
CGIG: 122404430
SOC: 105195910
MPHA: 105835292
AEC: 105153382
ACEP: 105619491
PBAR: 105425236
VEM: 105564271
HST: 105188235
DQU: 106742285
CFO: 105253055
FEX: 115235169
LHU: 105675813(ttv)
PGC: 109863645
OBO: 105287638
PCF: 106790860
PFUC: 122518599
VPS: 122631850
VCRB: 124426496
VVE: 124952716
NVI: 100120177
CSOL: 105364815
TPRE: 106653398
LHT: 122503992
LBD: 127289685
MDL: 103578696
CGLO: 123275072
FAS: 105268060
DAM: 107041901
AGIF: 122854354
CINS: 118067431
VCAN: 122409842
CCIN: 107267679
NPT: 124213539(ttv)
NFB: 124177902
NLO: 107220093
NVG: 124301106
AROA: 105688324
TCA: 657388
DPA: 109537981
SOY: 115875099
AGRG: 126748888
ATD: 109609672
CSET: 123321334
AGB: 108912966
LDC: 111502043
DVV: 114336209
DCOR: 135797169(ttv)
APLN: 108740927
PPYR: 116166831
OTU: 111414203
BMOR: 101736061
BMAN: 114249440
MSEX: 115448364
BANY: 112046889
MJU: 123875294
NIQ: 126771756
VCD: 124531698
MCIX: 123669423
PMAC: 106708978
PPOT: 106100685
PXU: 106124397
BPHI: 137926552(ttv)
PRAP: 111003256
PBX: 123716512
PNAP: 125049662
ZCE: 119829569
CCRC: 123705704
LSIN: 126966570
AAGE: 121730210
HAW: 110374076(ttv)
HZE: 124631134
TNL: 113496594
SLIU: 111353115
OFU: 114349767
ATRA: 106135529
GMW: 113518447
PGW: 126377613
LGLY: 125225474
CSTB: 134755872
CCRN: 123302491
API: 100167795
DNX: 107161983
AGS: 114120422
RMD: 113560806
ACOO: 126835201
DVT: 126905173
BTAB: 109034604
DCI: 103505288
CLEC: 106674189
HHAL: 106681771
NLU: 111055975
HVI: 124362624
MQU: 128989954
FOC: 113216463
TPAL: 117652466
ZNE: 110827878
CSEC: 111866884
SGRE: 126352265
BROR: 134535068
IEL: 124154440
FCD: 110847436
DMK: 116933752
DPZ: 124337515
PVM: 113802032
PJA: 122263365
PCHN: 125032085
PMOO: 119596794
HAME: 121869478
PCLA: 123769944
CQD: 128699795
PTRU: 123501535
MNZ: 135194969
MRJ: 136831668
HAZT: 108671440
EAF: 111700775
LSM: 121121323
TCF: 131883056
PPOI: 119102599
DSV: 119457583
RSAN: 119374094
RMP: 119167082
VDE: 111248228
VJA: 111265185
DPTE: 113796479
DFR: 124491080
CSCU: 111630346
CVS: 136988493(ttv)
PTEP: 107450714
ABRU: 129972503
UDV: 129230506
SDM: 118185853
PMEO: 129588086
CEL: CELE_F12F6.3(rib-1)
BMY: BM_BM3322(Bma-rib-1)
TSP: Tsp_04346
PVUL: 126808726
PCAN: 112561913
BGT: 106055537
GAE: 121376972
HRF: 124149462
HRJ: 124270731
HASI: 137277473
CRG: 105325442
CANU: 128181295
CVN: 111099932
OED: 125683894
MYI: 110443488
PMAX: 117317139
MCAF: 127732091
MMER: 123539606
RPHI: 132715401
DPOL: 127857791
MAEA: 128205603
OBI: 106867259
OSN: 115223691
LJP: 135463627
LAK: 106175986
EGL: EGR_02934
LLON: 135502896
NVE: 5505005
ATEN: 116307177
ADF: 107336815
AMIL: 114961284
PDAM: 113669827
SPIS: 111326534
DGT: 114528496
XEN: 124457859
HMG: 100208615
HSY: 130647744
RES: 135689667
AQU: 100641175
 » show all
Reference
PMID:9665133
  Authors
Bellaiche Y, The I, Perrimon N
  Title
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.
  Journal
Nature 394:85-8 (1998)
DOI:10.1038/27932
  Sequence
LinkDB

KEGG   ORTHOLOGY: K02367
Entry
K02367                      KO                                     
Symbol
EXT2
Name
glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]
Pathway
map00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
map01100  Metabolic pathways
Module
M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone
Reaction
R05935  
R10138  
R10139  
Disease
H00122  Multiple exostoses
H00493  Heparan sulfate proteoglycan gene defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.224  glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
     K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
    2.4.1.225  N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
     K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2
Other DBs
GO: 0050508 0050509
CAZy: GT47 GT64
Genes
HSA: 2132(EXT2)
PTR: 451140(EXT2)
PPS: 100975712(EXT2)
GGO: 101130563(EXT2)
PON: 100436160(EXT2)
PPYG: 129007272(EXT2)
NLE: 100604250(EXT2)
HMH: 116476325(EXT2)
SSYN: 129484203(EXT2)
MCC: 715975(EXT2)
MCF: 102136104(EXT2)
MTHB: 126936267
MNI: 105471617(EXT2)
CSAB: 103236980
CATY: 105586840(EXT2)
PANU: 101019229(EXT2)
TGE: 112606187(EXT2)
MLEU: 105554777(EXT2)
RRO: 104673882(EXT2)
RBB: 108519255(EXT2)
TFN: 117081393(EXT2)
PTEH: 111544934(EXT2)
CANG: 105527086(EXT2)
CJC: 100400679(EXT2)
SBQ: 101039408(EXT2)
CIMI: 108304907(EXT2)
ANAN: 105717305
MMUR: 105885490(EXT2)
LCAT: 123642622(EXT2)
PCOQ: 105819145(EXT2)
OGA: 100949922(EXT2)
MMU: 14043(Ext2)
MCAL: 110311448(Ext2)
MPAH: 110317782(Ext2)
RNO: 311215(Ext2)
MCOC: 116090518(Ext2)
ANU: 117703415(Ext2)
MUN: 110540376(Ext2)
CGE: 100751585(Ext2)
MAUA: 101842118(Ext2)
PROB: 127222213(Ext2)
PLEU: 114699729(Ext2)
MORG: 121440558(Ext2)
MFOT: 126504517
AAMP: 119814179(Ext2)
NGI: 103751554(Ext2)
HGL: 101715817(Ext2)
CPOC: 100712625(Ext2)
CCAN: 109686418
DORD: 105996073(Ext2)
DSP: 122100734(Ext2)
PLOP: 125362321(Ext2)
NCAR: 124960112
MMMA: 107135778(Ext2)
OCU: 100343697
OPI: 101536088(EXT2)
TUP: 102487057(EXT2)
GVR: 103596582(EXT2)
CFA: 475989(EXT2)
CLUD: 112663258(EXT2)
VVP: 112924118(EXT2)
VLG: 121501521(EXT2)
NPO: 129501308(EXT2)
AML: 105242037(EXT2)
UMR: 103672344(EXT2)
UAH: 113265012
UAR: 123799595(EXT2)
ELK: 111150031
LLV: 125078631
MPUF: 101672930(EXT2)
MLK: 131811678(EXT2)
NVS: 122912861(EXT2)
ORO: 101366478(EXT2)
EJU: 114215287(EXT2)
ZCA: 113914556(EXT2)
MLX: 118015783(EXT2)
NSU: 110576283(EXT2)
LWW: 102744900(EXT2)
FCA: 101083620(EXT2)
PYU: 121043515(EXT2)
PCOO: 112865217(EXT2)
PBG: 122483728(EXT2)
PVIV: 125176532(EXT2)
LRUF: 124504734
PTG: 102964333(EXT2)
PPAD: 109279210 109279211(EXT2)
PUC: 125928865
AJU: 106978049
HHV: 120228461(EXT2)
BTA: 281151(EXT2)
BOM: 102275740(EXT2)
BIU: 109569634(EXT2)
BBUB: 102389161(EXT2)
BBIS: 104982778(EXT2)
CHX: 102182243(EXT2)
OAS: 101110867(EXT2)
BTAX: 128060107(EXT2)
ODA: 120876908(EXT2)
CCAD: 122449196(EXT2)
MREE: 136174348(EXT2)
MBEZ: 129554774(EXT2)
SSC: 100522362(EXT2)
CFR: 102514905(EXT2)
CBAI: 105076487(EXT2)
CDK: 105106838(EXT2)
VPC: 102542570(EXT2)
BACU: 102999728(EXT2)
BMUS: 118899308(EXT2)
LVE: 103091009(EXT2)
OOR: 101280958(EXT2)
DLE: 111184011(EXT2)
PCAD: 102979294
PSIU: 116758175(EXT2)
NASI: 112402430(EXT2)
ECB: 100055879(EXT2)
EPZ: 103556459(EXT2)
EAI: 106843971(EXT2)
MYB: 102238781(EXT2)
MYD: 102767712(EXT2)
MMYO: 118665109(EXT2)
MLF: 102422014(EXT2)
MDT: 132241238(EXT2)
PKL: 118712503
EFUS: 103290862(EXT2)
MNA: 107525491(EXT2)
DRO: 112303473(EXT2)
SHON: 119002984(EXT2)
AJM: 119064418(EXT2)
PDIC: 114499874(EXT2)
PHAS: 123810129(EXT2)
MMF: 118627865(EXT2)
PPAM: 129081459(EXT2)
HAI: 109391972(EXT2)
RFQ: 117029882(EXT2)
PALE: 102890634(EXT2)
PGIG: 120606317
PVP: 105290068(EXT2)
RAY: 107511887(EXT2)
MJV: 108394755(EXT2)
TOD: 119255341(EXT2)
SARA: 101551336(EXT2)
SETR: 126017607(EXT2)
LAV: 100656016(EXT2)
TMU: 101361975
ETF: 101662457(EXT2)
DNM: 101436915(EXT2)
MDO: 100010947(EXT2)
SHR: 105750949(EXT2)
AFZ: 127541352
PCW: 110223945(EXT2)
TVP: 118854074(EXT2)
PBRV: 138163852(EXT2)
OAA: 100079286(EXT2)
GGA: 425859(EXT2)
PCOC: 116229130(EXT2)
MGP: 100545109
CJO: 107314816(EXT2)
TPAI: 128085844(EXT2)
LMUT: 125694790(EXT2)
NMEL: 110401311(EXT2)
APLA: 101790687(EXT2)
ACYG: 106044125(EXT2)
CATA: 118250771(EXT2)
AFUL: 116489660(EXT2)
TGU: 100231605(EXT2)
LSR: 110472037(EXT2)
SCAN: 103826716(EXT2)
PMOA: 120512558(EXT2)
OTC: 121333361(EXT2)
PRUF: 121349516(EXT2)
GFR: 102040196(EXT2)
FAB: 101814666(EXT2)
OMA: 130253844(EXT2)
PHI: 102107359(EXT2)
PMAJ: 107205846(EXT2)
CCAE: 111930141(EXT2)
CCW: 104695274(EXT2)
CBRC: 103620718(EXT2)
ETL: 114064860(EXT2)
ZAB: 102062154(EXT2)
ZLE: 135448536(EXT2)
SVG: 106851532(EXT2)
MMEA: 130572519(EXT2)
HRT: 120753978(EXT2)
SATI: 136362492(EXT2)
FPG: 101923547(EXT2)
FCH: 102054426(EXT2)
CCRI: 104157610(EXT2)
NNT: 104409474(EXT2)
SHAB: 115606439(EXT2)
ACUN: 113480641(EXT2)
TALA: 104367927(EXT2)
ACHC: 115333408(EXT2)
HLE: 104839720(EXT2)
AGEN: 126049243
GCL: 127017427
CSTI: 104550813(EXT2)
LDI: 104342773(EXT2)
DPUB: 104297453(EXT2)
PPUS: 135180185(EXT2)
AVIT: 104275926(EXT2)
BRHI: 104494174(EXT2)
EGZ: 104134053(EXT2)
NNI: 104019563(EXT2)
PCRI: 104037223(EXT2)
PCAO: 104039550(EXT2)
PADL: 103921685(EXT2)
AFOR: 103897455(EXT2)
FGA: 104079754(EXT2)
GSTE: 104250591(EXT2)
CLV: 102085197(EXT2)
MUI: 104538279(EXT2)
PLET: 104619405(EXT2)
EHS: 104506250(EXT2)
CMAC: 104482061
CUCA: 104067268(EXT2)
TEO: 104374413(EXT2)
BREG: 104639655
OHA: 104330168(EXT2)
CPEA: 104390387(EXT2)
CVF: 104295831(EXT2)
RTD: 128908421(EXT2)
AAM: 106498294(EXT2)
AROW: 112978433(EXT2)
NPD: 112943491(EXT2)
TGT: 104565017(EXT2)
DNE: 112979229(EXT2)
SCAM: 104149258(EXT2)
ASN: 102379048(EXT2)
AMJ: 102562202(EXT2)
CPOO: 109321140(EXT2)
GGN: 109298936(EXT2)
PSS: 102446763(EXT2)
CMY: 102938478(EXT2)
CCAY: 125638325(EXT2)
DCC: 119857262(EXT2)
CPIC: 101949276(EXT2)
TST: 117876973(EXT2)
CABI: 116830766(EXT2)
MRV: 120404543(EXT2)
ACS: 100555771(ext2)
ASAO: 132768475(EXT2)
PVT: 110081549(EXT2)
SUND: 121933481(EXT2)
PBI: 103062807(EXT2)
PMUR: 107302595(EXT2)
CTIG: 120307969(EXT2)
TSR: 106545012(EXT2)
PGUT: 117665492(EXT2)
APRI: 131187435(EXT2)
PTEX: 113440794(EXT2)
NSS: 113410220(EXT2)
VKO: 123026241(EXT2)
PMUA: 114596253(EXT2)
PRAF: 128413518(EXT2)
ZVI: 118085381(EXT2)
HCG: 128334415(EXT2)
GJA: 107122615(EXT2)
STOW: 125426333(EXT2)
EMC: 129324507(EXT2)
XLA: 380140(ext2.L) 398750(ext2.S)
XTR: 100151709(ext2)
NPR: 108786158(EXT2)
RTEM: 120917049(EXT2)
BBUF: 120980295(EXT2)
BGAR: 122920720(EXT2)
MUO: 115468808(EXT2)
GSH: 117352242(EXT2)
DRE: 493780(ext2)
CCAR: 109072430 109074535(ext2)
PTET: 122349070(ext2)
LROH: 127168414(ext2)
OMC: 131544219(ext2)
PPRM: 120468007(ext2)
RKG: 130102576(ext2)
MAMB: 125264629(ext2)
CIDE: 127515571
CERY: 137029879(ext2)
MASI: 127454839
TROS: 130556169(ext2)
TDW: 130425151(ext2)
MANU: 129441614(ext2)
IPU: 108271344
IFU: 128613387(ext2)
PHYP: 113536365(ext2)
SMEO: 124390802(ext2)
TFD: 113663258(ext2)
TVC: 132845376(ext2)
TRN: 134331470(ext2)
AMEX: 103046596(ext2)
CMAO: 118818835(ext2)
EEE: 113575759(ext2)
CHAR: 105907228(ext2)
TRU: 101066048(ext2)
TFS: 130521281(ext2)
LCO: 104919199(ext2)
NCC: 104963025(ext2)
TBEN: 117471545(ext2)
CGOB: 115006327(ext2)
PGEO: 117467212(ext2)
GACU: 117547083(ext2)
EMAC: 134863486(ext2)
ELY: 117258719(ext2)
EFO: 125881736(ext2)
PLEP: 121960250(ext2)
SLUC: 116034014(ext2)
ECRA: 117943850(ext2)
ESP: 116688651(ext2)
PFLV: 114553112(ext2)
GAT: 120808600(ext2)
PPUG: 119229335(ext2)
AFB: 129101386(ext2)
CLUM: 117725979(ext2)
PSWI: 130192468(ext2)
CANA: 137803781(ext2)
CVE: 137887787(ext2)
MSAM: 119890106(ext2)
SCHU: 122875957(ext2)
CUD: 121513674(ext2)
ALAT: 119017615(ext2)
ASTR: 137592938(ext2)
MZE: 101473582(ext2)
ONL: 100695641(ext2)
OAU: 116327190(ext2)
OLA: 101163398(ext2)
OML: 112160904(ext2)
CSAI: 133461580(ext2)
XMA: 102234444(ext2)
XCO: 114142777(ext2)
XHE: 116718349(ext2)
PRET: 103462432(ext2)
PFOR: 103139431(ext2)
PLAI: 106958190(ext2)
PMEI: 106926106(ext2)
GAF: 122821865(ext2)
PPRL: 129357919 129369640(ext2)
CVG: 107085591(ext2)
CTUL: 119782724(ext2)
GMU: 124866743(ext2)
NFU: 107381443(ext2)
KMR: 108228674(ext2)
ALIM: 106530767(ext2)
NWH: 119427822(ext2)
AOCE: 111574611(ext2)
MCEP: 125005111(ext2)
CSEM: 103378751(ext2)
POV: 109636768(ext2)
SSEN: 122772353(ext2)
HHIP: 117758296(ext2)
HSP: 118109144(ext2)
PPLT: 128440274(ext2)
SMAU: 118302515(ext2)
LCF: 108889668
SDU: 111238419(ext2)
SLAL: 111654812(ext2)
XGL: 120794269(ext2)
HCQ: 109514394(ext2)
SSCV: 125967040(ext2)
SBIA: 133498500(ext2)
PEE: 133399176(ext2)
PTAO: 133470770(ext2)
BPEC: 110172856(ext2)
MALB: 109965798(ext2)
BSPL: 114852235(ext2)
SJO: 128357971(ext2)
SASA: 100380322(ext2)
STRU: 115167097(ext2)
ONE: 115112435(ext2)
SALP: 111969484
SNH: 120049131
ELS: 105022258(ext2)
SFM: 108934682(ext2)
PKI: 111840708(ext2)
AANG: 118215430(ext2)
LOC: 102689027(ext2)
PSEX: 120517016(ext2)
LCM: 102363354(EXT2)
CMK: 103174976(ext2)
CPLA: 122558076(ext2)
HOC: 132824498(ext2)
LERI: 129705551(ext2)
PMRN: 116945549(EXT2)
LRJ: 133351349(EXT2)
BFO: 118408274
BBEL: 109480278
CIN: 100176235
SCLV: 120335699
APLC: 110981069
ARUN: 117291505
AJC: 117120899
DME: Dmel_CG8433(sotv)
DER: 6548926
DSE: 6609382
DSI: Dsimw501_GD25567(Dsim_GD25567)
DAN: 6495892
DSR: 110178267
DPO: 4803873
DPE: 6590702
DMN: 108159562
DWI: 6640721
DGR: 6560884
DAZ: 108615183
DNV: 108652943
DHE: 111600127
DVI: 6627192
CCAT: 101453656
BOD: 106618671
BDR: 105228094
RZE: 108368905
AOQ: 129244452
TDA: 119675557
MDE: 101901385
SCAC: 106082419
LCQ: 111677016
LSQ: 119600640
GFS: 119640251
ECOE: 129944140
CLON: 129605324
HIS: 119656850
AGA: 1272189
ACOZ: 120952216
AARA: 120906198
AMER: 121593113
ASTE: 118509916
AFUN: 125764791
AMOU: 128306730
AALI: 118459545
AAG: 5566768
AALB: 109397881
ASUA: 134207535
CPII: 120424304
CNS: 116349472
BCOO: 119081884
LLL: 129790538
PPAP: 129806250
AME: 726216
ACER: 107997927
ALAB: 122714818
ADR: 102680766
AFLR: 100867904
BIM: 100744382
BBIF: 117211962
BVK: 117239137
BVAN: 117166073
BHUN: 126875259
BTER: 100643223
BAFF: 126926220
BPYO: 122577021
BPAS: 132915143
FVI: 122535403
CCAL: 108622677
OBB: 114880970
OLG: 117601667
MGEN: 117224160
NMEA: 116429461
CGIG: 122399622
SOC: 105198634
MPHA: 105839250
AEC: 105150811
ACEP: 105627211
PBAR: 105427034
VEM: 105564746
HST: 105181013
DQU: 106750617
CFO: 105253243
FEX: 115240513
LHU: 105673709(sotv)
PGC: 109854839
PCF: 106791047
PFUC: 122523426
VPS: 122629883
VCRB: 124425504
VVE: 124949236
NVI: 100114642
CSOL: 105366129
LHT: 122511606
LBD: 127283446
MDL: 103580382
CGLO: 123268665
FAS: 105265574
DAM: 107040372
AGIF: 122851929
CINS: 118074555
VCAN: 122407576
CCIN: 107262845
DSM: 124408566
NPT: 124217576(sotv)
NFB: 124180268
NLO: 107218971
NVG: 124303405
AROA: 105685258
TCA: 659287
DPA: 109539467
SOY: 115885155
AGRG: 126743580
ATD: 109599451
CSET: 123316160
AGB: 108913506
LDC: 111509249
DVV: 114338127
NVL: 108557086
APLN: 108743766
OTU: 111419426
BMOR: 101741346
BMAN: 114247002
MSEX: 115440710
BANY: 112047335
MJU: 123870585
NIQ: 126772326
VCD: 124543422
MCIX: 123658419
PMAC: 106709701
PPOT: 106105805
PXU: 106121928
BPHI: 137933708(sotv)
PRAP: 110993283
PBX: 123713481
PNAP: 125056161
ZCE: 119834064
CCRC: 123696746
LSIN: 126974418
AAGE: 121733524
HAW: 110376090
HZE: 124633761
TNL: 113505944
SLIU: 111357626
OFU: 114352413
ATRA: 106137347
GMW: 113509908
PXY: 105394758
PGW: 126371220
LGLY: 125229496
CSTB: 134744564
CCRN: 123299680
API: 100164685
DNX: 107174001
AGS: 114131437
RMD: 113556757
ACOO: 126846336
DVT: 126893490
BTAB: 109035894
CLEC: 106673227
HHAL: 106678975(sotv)
NLU: 111056777
MQU: 128991922
FOC: 113211216
TPAL: 117652175
ZNE: 110831848
CSEC: 111872464
SGRE: 126297625
BROR: 134538741
IEL: 124157943
FCD: 110859221
DMK: 116934955
PJA: 122264403
PCHN: 125036743
PMOO: 119592442
HAME: 121864489
PCLA: 123758376
PTRU: 123501664
ESN: 126984445
MNZ: 135223631
MRJ: 136842590(sotv)
HAZT: 108677950
EAF: 111696021
LSM: 121117496
TCF: 131883327
DSV: 119464578
RSAN: 119402119
RMP: 119165413
VDE: 111251828
VJA: 111268602
TUT: 107361403
DPTE: 113789732
DFR: 124498786
CSCU: 111639960
CVS: 136972765(sotv)
PTEP: 107437365
ABRU: 129960529
UDV: 129231603
SDM: 118200215
LPOL: 106478475
PMEO: 129586373
BMY: BM_BM10349(Bma-rib-2)
PVUL: 126831214
PCAN: 112565643
BGT: 106058680
GAE: 121372488
HRF: 124138230
HASI: 137286532
CRG: 105324710
CANU: 128183294
OED: 125674228
MYI: 110451580
PMAX: 117326975
MCAF: 127725165
MMER: 123552181
RPHI: 132752103
DPOL: 127850329
MAEA: 128238651
OBI: 106868410
OSN: 115230884
LJP: 135463785
SHX: MS3_00006818(EXT2_1)
LLON: 135487508
NVE: 5510789
EPA: 110240280
ATEN: 116298104
AMIL: 114957442
PDAM: 113666284
SPIS: 111336973
DGT: 114537265
XEN: 124438051
HMG: 100212044
HSY: 130654077
RES: 135681776
AQU: 100636774
 » show all
Reference
PMID:9756849
  Authors
Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K
  Title
The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.
  Journal
J Biol Chem 273:26265-8 (1998)
DOI:10.1074/jbc.273.41.26265
  Sequence
[bta:281151]
LinkDB

KEGG   ENZYME: 2.4.1.224
Entry
EC 2.4.1.224                Enzyme                                 
Name
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
alpha-N-acetylglucosaminyltransferase II glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
Reaction(IUBMB)
UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan = UDP + N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan [RN:R07334]
Reaction(KEGG)
R07334 > R05936(G) R10139(G)
Substrate
UDP-N-acetyl-D-glucosamine [CPD:C00043];
beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan
Product
UDP [CPD:C00015];
N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan
Comment
Involved in the biosynthesis of heparin and heparan sulfate. Some forms of the enzyme from human (particularly the enzyme complex encoded by the EXT1 and EXT2 genes) act as bifunctional glycosyltransferases, which also have the 4-beta-glucuronosyltransferase (EC 2.4.1.225, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase) activity required for the synthesis of the heparan sulfate disaccharide repeats. Other human forms of this enzyme (e.g. the product of the EXTL1 gene) have only the 4-alpha-N-acetylglucosaminyltransferase activity. In Caenorhabditis elegans, the product of the rib-2 gene displays the activities of this enzyme as well as EC 2.4.1.223, glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase.
History
EC 2.4.1.224 created 2002
Pathway
ec00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
ec01100  Metabolic pathways
Orthology
K02366  glucuronyl/N-acetylglucosaminyl transferase EXT1
K02367  glucuronyl/N-acetylglucosaminyl transferase EXT2
K02368  alpha-1,4-N-acetylglucosaminyltransferase EXTL1
K02370  alpha-1,4-N-acetylglucosaminyltransferase EXTL3
Genes
HSA2131(EXT1) 2132(EXT2) 2134(EXTL1) 2137(EXTL3)
PTR107976420(EXT1) 451140(EXT2) 464086(EXTL3) 469238(EXTL1)
PPS100975712(EXT2) 100979888(EXTL1) 100984535(EXTL3) 100985695(EXT1)
GGO101130563(EXT2) 101144361(EXTL3) 101149310(EXTL1) 109025298(EXT1)
PON100172231(EXTL1) 100172450(EXT1) 100436160(EXT2) 100458560(EXTL3)
PPYG129007272(EXT2) 129041970(EXT1) 129043020(EXTL3) 129043026(EXTL1)
NLE100590557(EXTL3) 100597702(EXT1) 100604250(EXT2) 105738035(EXTL1)
HMH116461920(EXTL3) 116476325(EXT2) 116813105(EXTL1) 116813541(EXT1)
SSYN129472361(EXTL1) 129484203(EXT2) 129486743(EXT1) 129491457(EXTL3)
MCC100426593(EXTL3) 701488(EXT1) 713664(EXTL1) 715975(EXT2)
MCF101865433(EXTL3) 101926231(EXT1) 102125916(EXTL1) 102136104(EXT2)
MTHB126936267 126955021 126961556 126961764
MNI105468540(EXT1) 105471617(EXT2) 105481991(EXTL3) 105494488(EXTL1)
CSAB103215549(EXTL3) 103225338(EXTL1) 103236980 103237338(EXT1)
CATY105579157(EXTL3) 105584539(EXT1) 105586840(EXT2) 105594948(EXTL1)
PANU100137439(EXT1) 101001089(EXTL3) 101009465(EXTL1) 101019229(EXT2) 116272456 116272614
TGE112606187(EXT2) 112608368(EXTL1) 112629920(EXT1) 112630110(EXTL3)
MLEU105529083 105540874(EXTL1) 105542360(EXTL3) 105554777(EXT2)
RRO104656082(EXTL1) 104658897(EXT1) 104668244(EXTL3) 104673882(EXT2)
RBB108518038(EXTL1) 108519255(EXT2) 108536176(EXT1) 108537365(EXTL3)
TFN117079472(EXT1) 117081393(EXT2) 117093079(EXTL1) 117094279(EXTL3)
PTEH111544934(EXT2) 111545749(EXTL3) 111547509(EXTL1) 111551020(EXT1)
CANG105511053(EXT1) 105513644(EXTL3) 105521399(EXTL1) 105527086(EXT2)
CJC100386964(EXT1) 100400452(EXTL3) 100400679(EXT2) 100412852(EXTL1)
SBQ101037632(EXTL3) 101039408(EXT2) 101053138(EXTL1) 101053444(EXT1)
CIMI108304907(EXT2) 108305915(EXT1) 108308708(EXTL1) 108312491(EXTL3)
ANAN105705348(EXTL3) 105708618(EXTL1) 105710789(EXT1) 105717305
CSYR103260803 103263660 103264178 103267603(EXTL1) 103272211(EXTL3) 103272774
MMUR105863568(EXTL1) 105863703(EXT1) 105877144(EXTL3) 105885490(EXT2)
LCAT123626528(EXTL3) 123634380(EXTL1) 123642622(EXT2) 123645168(EXT1)
PCOQ105811644(EXTL1) 105812176(EXT1) 105818825(EXTL3) 105819145(EXT2)
OGA100940987(EXTL1) 100943601(EXT1) 100949922(EXT2) 100956398(EXTL3)
MMU14042(Ext1) 14043(Ext2) 54616(Extl3) 56219(Extl1)
MCAL110292428(Extl1) 110309303(Extl3) 110310432(Ext1) 110311448(Ext2)
MPAH110317782(Ext2) 110323450(Extl1) 110325330(Extl3) 110334870(Ext1)
RNO299907(Ext1) 311215(Ext2) 313610(Extl1) 56819(Extl3)
MCOC116082489(Ext1) 116084271(Extl3) 116090518(Ext2) 116096808(Extl1)
ANU117703415(Ext2) 117705250(Extl3) 117708283(Extl1)
MUN110540376(Ext2) 110552198(Extl1) 110559132(Extl3) 110559447(Ext1)
CGE100689334(Ext1) 100751585(Ext2) 100751999(Extl3) 100770000(Extl1)
MAUA101826524(Ext1) 101832900(Extl3) 101833528(Extl1) 101842118(Ext2)
PROB127213365(Extl1) 127222213(Ext2) 127227926 127230258(Extl3) 127235391(Ext1)
PLEU114694845(Ext1) 114697258 114699729(Ext2) 114705983 114707292(Extl3)
MORG121440558(Ext2) 121448536(Extl1) 121457116(Extl3) 121461166(Ext1)
MFOT126491860 126504517 126507662 126508161
AAMP119800335(Extl3) 119814179(Ext2) 119816389(Extl1) 119822782(Ext1)
NGI103729989(Extl3) 103737100(Extl1) 103738135(Ext1) 103751554(Ext2)
HGL101697847(Extl3) 101705292(Extl1) 101706257(Ext1) 101715817(Ext2)
CPOC100712625(Ext2) 100716129(Extl3) 100716132(Ext1) 100732210(Extl1)
CCAN109682613 109683077(Extl1) 109686418 109702003
DORD105991591(Extl3) 105996073(Ext2) 105997725(Ext1) 105998840(Extl1)
DSP122100734(Ext2) 122102360(Ext1) 122115278(Extl1) 122125248(Extl3)
PLOP125339456(Extl3) 125354751(Extl1) 125360972(Ext1) 125362321(Ext2)
NCAR124960112 124961920 124981119 124983066
MMMA107135778(Ext2) 107142097(Extl1) 107142875(Ext1) 107153879(Extl3)
OCU100343697 100347418 100348721 100351235
OPI101533034(EXTL1) 101535829(EXT1) 101536088(EXT2) 101536233(EXTL3)
TUP102467803(EXT1) 102472563(EXTL3) 102487057(EXT2) 102499532(EXTL1)
GVR103585081(EXTL1) 103591115(EXT1) 103596582(EXT2) 103599679(EXTL3)
CFA475989(EXT2) 482024(EXT1) 486091(EXTL3) 487363(EXTL1)
CLUD112660062(EXTL1) 112662087(EXT1) 112663258(EXT2) 112669674(EXTL3)
VVP112915941(EXT1) 112924118(EXT2) 112926771(EXTL3) 112931669(EXTL1)
VLG121496756(EXTL3) 121497437(EXTL1) 121498758(EXT1) 121501521(EXT2)
NPO129501308(EXT2) 129502436(EXT1) 129514172(EXTL1) 129523428(EXTL3)
AML100465258(EXT1) 100469588(EXTL3) 100482562(EXTL1) 105242037(EXT2)
UMR103661582(EXT1) 103666523(EXTL1) 103672344(EXT2) 103675952(EXTL3)
UAH113252791(EXT1) 113265012 113268473(EXTL1) 113269941(EXTL3)
UAR123777356(EXTL3) 123782477(EXTL1) 123797768(EXT1) 123799595(EXT2)
ELK111146555 111150031 111153998 111154894
LLV125078631 125092954 125097162 125098595
MPUF101672930(EXT2) 101674896(EXTL3) 101683113(EXTL1) 101691546(EXT1)
MNP131999612(EXTL3) 132001828(EXTL1) 132008192 132008356 132014249(EXT1)
MLK131809414(EXTL1) 131811678(EXT2) 131826469(EXT1) 131833485(EXTL3)
NVS122889680(EXTL3) 122899602(EXTL1) 122904351(EXT1) 122912861(EXT2)
ORO101366478(EXT2) 101377818(EXTL3) 101379569(EXTL1) 101382133(EXT1)
EJU114199089(EXT1) 114215287(EXT2) 114217203(EXTL1) 114217463(EXTL3)
ZCA113913370(EXTL1) 113914556(EXT2) 113924330(EXTL3) 113931105(EXT1)
MLX118015150(EXT1) 118015783(EXT2) 118019850(EXTL1) 118022124(EXTL3)
NSU110574778(EXTL1) 110576283(EXT2) 110579220(EXT1) 110588579(EXTL3)
LWW102731787(EXTL3) 102741200(EXT1) 102742248(EXTL1) 102744900(EXT2)
FCA101081362(EXT1) 101083620(EXT2) 101083693(EXTL1) 101095491(EXTL3)
PYU121023608(EXTL1) 121024917(EXTL3) 121042894(EXT1) 121043515(EXT2)
PCOO112848519(EXTL1) 112858631(EXTL3) 112859477(EXT1) 112865217(EXT2)
PBG122474042(EXTL3) 122480109(EXTL1) 122483728(EXT2) 122495739(EXT1)
PVIV125156370(EXT1) 125163342(EXTL3) 125173399(EXTL1) 125176532(EXT2)
LRUF124504734 124507771 124514508 124520638
PTG102961650(EXTL3) 102962317(EXTL1) 102964333(EXT2) 102968916(EXT1)
PPAD109256806(EXTL1) 109262363(EXTL3) 109273237(EXT1) 109279210 109279211(EXT2)
PUC125912921 125923797 125924455 125928865
AJU106975536 106977618 106978049 106983017
HHV120220154(EXTL3) 120228461(EXT2) 120228668(EXT1) 120230901(EXTL1)
BTA281151(EXT2) 511060(EXTL1) 538602(EXT1) 783970(EXTL3)
BOM102267135(EXTL1) 102273632(EXTL3) 102275740(EXT2) 102280308(EXT1)
BIU109562800(EXTL3) 109568471(EXT1) 109569634(EXT2) 109573580(EXTL1)
BBUB102389161(EXT2) 102398616(EXTL3) 102407802(EXT1) 102415224(EXTL1)
BBIS104981139(EXTL1) 104982778(EXT2) 104988830(EXTL3) 105005436(EXT1)
CHX102178172(EXTL3) 102182004(EXTL1) 102182243(EXT2) 102182809(EXT1)
OAS101108814(EXTL3) 101110867(EXT2) 101113394(EXTL1) 101114877(EXT1)
BTAX128052260(EXTL3) 128059226(EXT1) 128060107(EXT2) 128070476(EXTL1)
ODA120855039(EXTL1) 120860402(EXTL3) 120860718 120876908(EXT2) 120878901(EXT1)
CCAD122426536(EXTL1) 122449196(EXT2) 122450981(EXT1) 122452882(EXTL3)
MREE136144866(EXT1) 136148471(EXTL3) 136164728(EXTL1) 136174348(EXT2)
MBEZ129537628(EXTL1) 129554774(EXT2) 129557494(EXTL3) 129559842(EXT1)
SSC100152703(EXTL3) 100157655(EXT1) 100522362(EXT2) 100623848(EXTL1)
CFR102507432(EXTL3) 102508456(EXT1) 102514905(EXT2) 102521830(EXTL1)
CBAI105063480(EXTL1) 105076487(EXT2) 105079118(EXTL3) 105082972(EXT1)
CDK105096148(EXT1) 105100672(EXTL1) 105102072(EXTL3) 105106838(EXT2)
VPC102532676(EXTL3) 102535018(EXT1) 102542570(EXT2) 102544441(EXTL1)
BACU102999728(EXT2) 103004222(EXTL1) 103009480(EXTL3) 103019432(EXT1)
BMUS118883288(EXT1) 118896886(EXTL3) 118899308(EXT2) 118906869(EXTL1)
LVE103068452(EXTL1) 103078702(EXTL3) 103078738(EXT1) 103091009(EXT2)
OOR101280958(EXT2) 101281062(EXTL1) 101286194(EXTL3) 101286251(EXT1)
DLE111163234(EXTL1) 111165183(EXT1) 111184011(EXT2) 111185386(EXTL3)
PCAD102979294 102980097(EXT1) 102983199(EXTL1) 102995934(EXTL3)
PSIU116738709(EXTL1) 116742524(EXT1) 116755265(EXTL3) 116758175(EXT2)
NASI112397180(EXT1) 112400931(EXTL3) 112402430(EXT2) 112414247(EXTL1)
ECB100054778(EXTL3) 100055879(EXT2) 100056983(EXT1) 100071242(EXTL1)
EPZ103549478(EXT1) 103556459(EXT2) 103556774(EXTL1) 103567372(EXTL3)
EAI106832529(EXTL3) 106839736(EXT1) 106839934(EXTL1) 106843971(EXT2)
MYB102238781(EXT2) 102244714(EXT1) 102246778(EXTL1) 102250952(EXTL3)
MYD102761567(EXTL1) 102764127(EXTL3) 102765321(EXT1) 102767712(EXT2)
MMYO118657784(EXTL3) 118665109(EXT2) 118670761(EXT1) 118676894(EXTL1)
MLF102422014(EXT2) 102429540(EXTL1) 102437020(EXTL3) 102441376(EXT1)
MDT132219587(EXT1) 132231502(EXTL1) 132235347(EXTL3) 132241238(EXT2)
PKL118710818(EXTL3) 118712503 118718227(EXT1) 118723646(EXTL1)
EFUS103287659(EXT1) 103290862(EXT2) 103292066(EXTL1) 103294344(EXTL3)
MNA107525491(EXT2) 107533185(EXT1) 107537770(EXTL3) 107541891(EXTL1)
DRO112299237(EXTL1) 112303473(EXT2) 112312602(EXTL3) 112315333(EXT1)
SHON118977808(EXTL1) 118984343(EXTL3) 118988619(EXT1) 119002984(EXT2)
AJM119042253(EXTL1) 119051826(EXT1) 119053020(EXTL3) 119053021 119064418(EXT2)
PDIC114498143(EXTL1) 114499874(EXT2) 114502307(EXTL3) 114514407(EXT1)
PHAS123810129(EXT2) 123813737(EXTL3) 123832033(EXTL1) 123833269(EXT1)
MMF118615157(EXTL3) 118627094(EXTL1) 118627865(EXT2) 118631561(EXT1)
PPAM129069197(EXTL1) 129072542(EXTL3) 129081459(EXT2) 129084291(EXT1)
HAI109379533(EXTL3) 109382533 109386781(EXTL1) 109391972(EXT2)
RFQ117027039(EXTL1) 117029882(EXT2) 117033795(EXT1) 117037898(EXTL3)
PALE102889624(EXTL3) 102890634(EXT2) 102891150(EXT1) 102894796(EXTL1)
PGIG120595391(EXT1) 120596043(EXTL1) 120606317 120613246(EXTL3)
PVP105290068(EXT2) 105290678(EXTL1) 105291510(EXTL3) 105292239(EXT1)
RAY107502529(EXTL1) 107507149(EXT1) 107510781(EXTL3) 107511887(EXT2)
MJV108391555(EXTL3) 108394755(EXT2) 108398779(EXTL1) 108399086(EXT1)
TOD119236338(EXTL1) 119238592(EXT1) 119255341(EXT2) 119258027(EXTL3)
SARA101538625(EXT1) 101551336(EXT2) 101555783(EXTL1) 101556463(EXTL3)
SETR126005798(EXTL3) 126009054(EXT1) 126011055(EXTL1) 126017607(EXT2)
LAV100656016(EXT2) 100657623(EXT1) 100666182(EXTL3) 100673302(EXTL1)
TMU101348092 101358076 101361975 101362012
ETF101638077(EXTL3) 101661672(EXT1) 101662457(EXT2) 101662981(EXTL1)
DNM101426325(EXTL1) 101436351(EXT1) 101436915(EXT2) 101446669(EXTL3)
MDO100010947(EXT2) 100015039(EXTL1) 100025396(EXT1) 100030828(EXTL3)
GAS123234817(EXTL3) 123241026(EXTL1) 123241182(EXT1) 123252570 123252571
SHR100918977(EXTL1) 100919560(EXTL3) 100929895(EXT1) 105750949(EXT2)
AFZ127541352 127544392 127548355 127555663
PCW110200303(EXT1) 110206108(EXTL1) 110209977(EXTL3) 110223945(EXT2)
TVP118837393(EXTL1) 118843067(EXTL3) 118851574(EXT1) 118854074(EXT2)
PBRV138152008(EXTL3) 138154242(EXTL1) 138155837(EXT1) 138163852(EXT2)
OAA100078206(EXT1) 100079286(EXT2) 100087229(EXTL3)
GGA100858205(EXT1) 100859367(EXTL1) 422022(EXTL3) 425859(EXT2)
PCOC116227694(EXT1) 116229130(EXT2) 116230047(EXTL1) 116235605(EXTL3)
MGP100542119(EXT1) 100542317(EXTL3) 100545109 100551486(EXTL1)
CJO107310492(EXT1) 107312356(EXTL3) 107314816(EXT2) 107324063(EXTL1)
TPAI128084759(EXTL3) 128085844(EXT2) 128088342(EXTL1) 128090880(EXT1)
LMUT125689758(EXTL3) 125691409(EXT1) 125694790(EXT2) 125703958(EXTL1)
NMEL110387476(EXTL1) 110395119(EXT1) 110396622(EXTL3) 110401311(EXT2)
APLA101790687(EXT2) 101791181(EXTL3) 101792373(EXT1) 119713596(EXTL1)
ACYG106037911(EXTL1) 106038151(EXTL3) 106038456(EXT1) 106044125(EXT2)
CATA118250771(EXT2) 118252659(EXT1) 118255759(EXTL1) 118256519(EXTL3)
AFUL116485915(EXT1) 116487389(EXTL3) 116489660(EXT2) 116498028(EXTL1)
TGU100227900(EXT1) 100228076(EXTL3) 100231605(EXT2) 115498288(EXTL1)
LSR110472037(EXT2) 110472893(EXTL1) 110476418(EXTL3) 110479282(EXT1)
SCAN103814231(EXT1) 103821407(EXTL3) 103823579(EXTL1) 103826716(EXT2)
PMOA120496811(EXTL3) 120505159(EXT1) 120512558(EXT2) 120513889(EXTL1)
OTC121333361(EXT2) 121337462(EXT1) 121342741(EXTL1) 121347459(EXTL3)
PRUF121349516(EXT2) 121351215(EXTL1) 121355356(EXT1) 121360869(EXTL3)
GFR102035022(EXTL1) 102040196(EXT2) 102041533(EXTL3) 102043948(EXT1)
FAB101814666(EXT2) 101816822(EXT1) 101818645(EXTL3) 101818678(EXTL1)
OMA130249178(EXT1) 130250595(EXTL3) 130253844(EXT2) 130262245(EXTL1)
PHI102099981(EXT1) 102105383(EXTL3) 102107359(EXT2) 102111356(EXTL1)
PMAJ107200137(EXT1) 107201996(EXTL3) 107205846(EXT2) 107213996(EXTL1)
CCAE111925064(EXT1) 111927356(EXTL3) 111930141(EXT2)
CCW104692676(EXT1) 104695274(EXT2) 104696886(EXTL3)
CBRC103613283(EXTL3) 103616910(EXTL1) 103620718(EXT2) 103623522(EXT1)
ETL114057979(EXT1) 114064860(EXT2) 114068426(EXTL3) 114070342(EXTL1)
ZAB102062154(EXT2) 102067827(EXT1) 102071380(EXTL3)
ZLE135444634(EXT1) 135446253(EXTL3) 135448536(EXT2) 135457261(EXTL1)
ACHL103799017(EXTL3) 103805479(EXT1)
SVG106849477(EXT1) 106851532(EXT2) 106859333(EXTL3) 106861906(EXTL1)
MMEA130572519(EXT2) 130574552(EXT1) 130583292(EXTL1) 130585825(EXTL3)
HRT120750589(EXTL3) 120753978(EXT2) 120758554(EXT1) 120763137(EXTL1)
SATI136358665(EXTL3) 136362492(EXT2) 136371154(EXTL1) 136371196(EXT1)
FPG101917228(EXTL3) 101919384(EXT1) 101922176(EXTL1) 101923547(EXT2)
FCH102049940(EXT1) 102054426(EXT2) 102056733(EXTL3) 102056866(EXTL1)
CCRI104157610(EXT2) 104160702(EXTL3) 104162814(EXT1)
NNT104403804(EXT1) 104409474(EXT2) 104412037(EXTL3)
SHAB115606439(EXT2) 115609420(EXTL3) 115609772(EXT1) 115615978(EXTL1)
ACUN113476897(EXT1) 113478245(EXTL3) 113480641(EXT2) 113488189(EXTL1)
TALA104357343(EXTL3) 104365235(EXT1) 104367927(EXT2) 116964263(EXTL1)
ACHC115333408(EXT2) 115340329(EXT1) 115350851(EXTL3) 115351760(EXTL1)
HALD104321672(EXTL3)
HLE104837180(EXTL1) 104837692(EXT1) 104839720(EXT2) 104841461(EXTL3)
AGEN126046580 126047399 126049009 126049243
GCL127012556 127014359 127017427 127025047
CSTI104549396(EXTL3) 104550813(EXT2) 104555699 104561130
LDI104342773(EXT2) 104343812(EXTL3) 104349538(EXT1)
MNB103779575(EXTL3)
DPUB104297238(EXT1) 104297453(EXT2) 104306733(EXTL3) 104307496(EXTL1)
PPUS135177027(EXTL3) 135180185(EXT2) 135181208(EXT1) 135190941(EXTL1)
AVIT104274080(EXTL3) 104275926(EXT2) 104279093(EXT1)
BRHI104494174(EXT2) 104496894(EXT1) 104502149(EXTL3)
EGZ104123693(EXT1) 104127251(EXTL3) 104134053(EXT2) 104134955(EXTL1)
NNI104014701(EXTL3) 104017847(EXTL1) 104018021(EXT1) 104019563(EXT2)
PCRI104029465(EXTL3) 104037223(EXT2) 104037444
PCAO104039550(EXT2) 104049419 104050326(EXTL3)
PADL103913240(EXTL3) 103914958(EXT1) 103921685(EXT2)
AFOR103896426(EXTL1) 103897223(EXT1) 103897455(EXT2) 103902390(EXTL3)
FGA104079754(EXT2) 104080655(EXT1) 104080989(EXTL3)
GSTE104250591(EXT2) 104256723(EXTL3)
CLV102084082(EXTL1) 102085197(EXT2) 102088676(EXTL3) 102091811(EXT1)
MUI104533346(EXTL3) 104538279(EXT2) 104542233 104542281(EXTL1)
PGUU104464178(EXTL3)
PLET104618170 104619405(EXT2) 104627152(EXTL3)
EHS104506250(EXT2) 104510203(EXT1) 104512433(EXTL3)
CMAC104481663 104482061 104487447(EXTL3)
CUCA104061521(EXTL1) 104061793(EXTL3) 104066187(EXT1) 104067268(EXT2)
TEO104372233 104374413(EXT2) 104383215(EXTL3)
BREG104638922(EXTL3) 104639655 104641383(EXT1)
OHA104329677(EXTL3) 104330168(EXT2) 104332486(EXT1)
ACAR104527822(EXTL3)
CPEA104386715(EXT1) 104390387(EXT2) 104392750(EXTL3) 104394116(EXTL1)
CVF104282894(EXT1) 104283937(EXTL1) 104295670(EXTL3) 104295831(EXT2)
RTD128904733(EXT1) 128906659(EXTL3) 128908421(EXT2) 128919015(EXTL1)
AAM106485009 106488030(EXTL3) 106496271(EXT1) 106498294(EXT2) 106499622
AROW112960952(EXT1) 112964418(EXTL1) 112966640(EXTL3) 112972955 112978433(EXT2)
NPD112943491(EXT2) 112948502(EXT1) 112948868(EXTL3) 112950897(EXTL1)
TGT104565017(EXT2) 104573294 104575616(EXTL3)
DNE112979229(EXT2) 112982032(EXTL1) 112984257(EXTL3) 112989149(EXT1)
SCAM104139003(EXTL3) 104149258(EXT2) 104150074(EXT1)
ASN102370729(EXT1) 102376854(EXTL1) 102377426(EXTL3) 102379048(EXT2)
AMJ102560415(EXT1) 102562202(EXT2) 102575775(EXTL3) 102575942(EXTL1)
CPOO109311530(EXTL3) 109318544(EXTL1) 109321140(EXT2) 109321481(EXT1)
GGN109294162(EXTL1) 109298936(EXT2) 109299004(EXT1) 109300230(EXTL3)
PSS102444477(EXT1) 102446763(EXT2) 102462577(EXTL3)
CMY102929859(EXTL1) 102938478(EXT2) 102939595(EXT1) 102945736(EXTL3)
CCAY125624786(EXTL1) 125632784(EXT1) 125634721(EXTL3) 125634923 125638325(EXT2)
DCC119845550(EXTL1) 119852082(EXT1) 119852576 119852912(EXTL3) 119857262(EXT2)
CPIC101935250(EXTL3) 101946173(EXT1) 101949276(EXT2) 101953823(EXTL1) 103307378
TST117868243(EXTL1) 117873767(EXT1) 117875421(EXTL3) 117876973(EXT2)
CABI116818811(EXT1) 116830766(EXT2) 116831110(EXTL3) 116837997(EXTL1)
MRV120389310(EXTL1) 120398808(EXT1) 120401043(EXTL3) 120404543(EXT2)
ACS100553800(extl1) 100555771(ext2) 100557117(extl3) 100567014(ext1)
ASAO132761634(EXTL3) 132768475(EXT2) 132775071(EXT1) 132780719(EXTL1)
PVT110070203(EXTL3) 110076972(EXT1) 110081549(EXT2) 110084159(EXTL1)
SUND121915625(EXTL1) 121920560(EXTL3) 121928875(EXT1) 121933481(EXT2)
PBI103048904 103054708 103060383(EXTL3) 103062807(EXT2) 103067611(EXTL1)
PMUR107284865(EXTL3) 107292260 107295666(EXTL1) 107302595(EXT2)
CTIG120307392(EXT1) 120307969(EXT2) 120309096(EXTL3) 120314310(EXTL1)
TSR106538947 106539688(EXTL1) 106541899(EXTL3) 106545012(EXT2)
PGUT117663388(EXTL1) 117665492(EXT2) 117667705(EXTL3) 117668371(EXT1)
APRI131187435(EXT2) 131189026(EXTL3) 131196014(EXT1) 131204188(EXTL1)
PTEX113437525(EXTL1) 113438272(EXT1) 113440794(EXT2) 113446365(EXTL3)
NSS113410220(EXT2) 113414570(EXTL3) 113417566(EXTL1) 113427134(EXT1)
VKO123019173(EXT1) 123025901(EXTL1) 123026241(EXT2) 123033591(EXTL3)
PMUA114594927(EXTL3) 114596253(EXT2) 114601312(EXT1) 114601546(EXTL1)
PRAF128411453(EXTL3) 128413518(EXT2) 128417122(EXT1) 128418730(EXTL1)
ZVI118082960(EXTL3) 118085381(EXT2) 118086449(EXTL1) 118089708(EXT1)
HCG128323737(EXT1) 128324488(EXTL3) 128333382(EXTL1) 128334415(EXT2)
GJA107106370(EXTL3) 107110827(EXTL1) 107113379 107122615(EXT2)
STOW125426333(EXT2) 125434955(EXTL1) 125439498(EXT1) 125444573(EXTL3)
EMC129324507(EXT2) 129333222(EXT1) 129335651(EXTL3) 129343175(EXTL1)
XLA380140(ext2.L) 398214(ext1.L) 398750(ext2.S) 399115(ext1.S) 444275(extl3.S) 447542(extl3.L)
XTR100151709(ext2) 448393(ext1) 493398(extl3)
NPR108786158(EXT2) 108790563(EXT1) 108802201(EXTL3)
RTEM120917049(EXT2) 120936038(EXTL3) 120941479(EXT1)
BBUF120980295(EXT2) 120997178(EXTL3) 121001066(EXT1)
BGAR122920720(EXT2) 122934492(EXTL3) 122938154(EXT1)
MUO115464768 115467040(EXTL3) 115468808(EXT2) 115479964(EXT1) 115480317(EXTL1)
GSH117352242(EXT2) 117355075(EXT1) 117357293(EXTL3) 117357489 117365871(EXTL1)
DRE101885478 493780(ext2) 493783(extl3) 497279(ext1a) 497280(ext1b) 497281(ext1c)
SRX107706235(extl1) 107706241 107711539 107715577 107719384 107727350 107733302 107745900 107750554 107754264 107754269 107754691
SANH107654722 107654729 107659874 107669453 107671371 107671458 107683605 107685778 107688159(ext2) 107688215 107688378 107696533 107704067
SGH107548434 107558762 107559127 107562300 107586005 107592048(extl1) 107592050 107592164 107592487 107592940 107592945 107593432
CCAR109050531 109056569 109059721 109072430 109074535(ext2) 109075419 109075422 109093562 109106263 109109198 109109965 109111718 109112811 109112812 109113082
CAUA113052033 113062235 113062294 113062301 113063437 113068614 113073234 113083119 113105758 113115689 113119245 113119254 113120607 113121224
CGIB127935072 127935393 127938411 127938533 127962006 127975010 127978542 127979490 127983603 127984120 128017046 128030806
PTET122323313 122323527(ext1b) 122324020(ext1c) 122324433 122324897(extl3) 122333980(ext1a) 122333996 122349070(ext2)
LROH127168414(ext2) 127178446(ext1a) 127181513(ext1b) 127181899(ext1c) 127182637 127183219(extl3)
OMC131521901(ext1a) 131525465 131526332(ext1b) 131527401(extl3) 131527582 131544219(ext2)
PPRM120468007(ext2) 120469966(ext1c) 120479262(ext1b) 120491188(ext1a) 120492082(extl3) 120493730
RKG130078411(ext1a) 130096027 130096184(extl3) 130102576(ext2)
MAMB125243241(ext1a) 125264629(ext2) 125275117(ext1b) 125275126 125278709(extl3) 125278978
CIDE127497257 127497324 127500934 127501221 127502195 127502442 127515571
CERY137001981 137018674 137019222(extl3) 137029879(ext2) 137037540(ext1b) 137037953(ext1a)
MASI127409609 127415541 127420630 127420631 127425512 127425513 127453101 127454129 127454839
TROS130551302 130556169(ext2) 130557989(ext1a) 130566024(extl3) 130566509(ext1b) 130566756
TDW130415440(ext1b) 130415633 130425151(ext2) 130432903(ext1a) 130434804(extl3) 130434877
MANU129429405(extl3) 129441614(ext2) 129448753(ext1a) 129454424(ext1b) 129454464
IPU108256617(ext1a) 108257122(ext1b) 108257140 108257719 108271344 108275270
IFU128599505(ext1a) 128600187 128600192(ext1b) 128601090(extl3) 128613387(ext2) 128619295
PHYP113529295 113532052(extl3) 113532714 113535947 113535988 113536365(ext2)
SMEO124375785(ext1b) 124375938 124377167(extl3) 124390802(ext2) 124401370 124403868(ext1a)
TFD113643961(ext1c) 113649722(ext1a) 113654795 113655598(extl3) 113661608(ext1b) 113663258(ext2)
TVC132837615 132839969(ext1a) 132843161(extl3) 132845376(ext2) 132854431 132863853(ext1b)
TRN134300836(ext1a) 134320350(extl3) 134320439 134331470(ext2) 134331573 134331607(ext1b)
AMEX103026919 103031914(ext1b) 103040053(ext1a) 103041905(extl3) 103046596(ext2) 103047171
CMAO118798675(ext1a) 118805664(ext1b) 118805672 118815270 118815813(extl3) 118818835(ext2)
EEE113571699(extl3) 113575759(ext2) 113578814 113588018(ext1) 113591568 113591687
CHAR105891959 105897019 105904948(ext1b) 105907228(ext2) 105907280(extl3) 105909063(ext1c)
TRU101065654 101066048(ext2) 101068405(extl3) 101072426 101072822 101075972
TFS130515800(extl3) 130516284 130518042(ext1b) 130518113(ext1c) 130521281(ext2) 130532494
TNGGSTEN00017827G001 GSTEN00023018G001 GSTEN00032917G001 GSTEN00032935G001 GSTEN00035381G001 GSTEN00038113G001
LCO104919199(ext2) 104926220 104931682 104932462 104934376(extl3) 104937142
NCC104945394 104946504(extl3) 104949435 104961795(ext1) 104963025(ext2)
TBEN117471545(ext2) 117477648(ext1b) 117477663(ext1c) 117480396 117486878 117487005(extl3)
CGOB115003439 115006327(ext2) 115015568 115016180 115021154
PGEO117439554(extl3) 117439799 117454828(ext1b) 117455536 117460478 117467212(ext2)
GACU117535645 117537462 117542614 117545386(ext1c) 117547083(ext2) 117548851(extl3)
EMAC134861875 134863486(ext2) 134874992 134875490(ext1b) 134876603 134876927(extl3)
ELY117258719(ext2) 117263289(ext1b) 117263650 117265950 117270842 117270963(extl3)
EFO125881736(ext2) 125893291 125897137(extl3) 125897583 125904485 125904491(ext1b)
PLEP121945585 121955317 121955766(extl3) 121958010(ext1b) 121958038 121960250(ext2)
SLUC116034014(ext2) 116035281 116047237(ext1c) 116047249(ext1b) 116065957(extl3) 116066120
ECRA117943850(ext2) 117946948 117956425(ext1b) 117956791 117961813 117961814 117961987(extl3)
ESP116688651(ext2) 116690738 116701186 116701221 116706523 116706858(extl3)
PFLV114553112(ext2) 114557177 114567744 114567814 114572953 114573362(extl3)
GAT120807940 120807950(extl3) 120808600(ext2) 120810156 120826358(ext1b) 120826673(ext1c)
PPUG119194732(extl3) 119195167 119197352 119219177(ext1b) 119219200 119229335(ext2)
AFB129096805(ext1c) 129097306(ext1b) 129101386(ext2) 129107447(extl3) 129107479 129109669
CLUM117725979(ext2) 117727284 117727521(extl3) 117738620(ext1c) 117739586(ext1b) 117745311
PSWI130192468(ext2) 130194589(ext1b) 130197680 130202270(extl3) 130202948 130212600
CANA137784405(ext1c) 137784486(ext1b) 137785399 137785410(extl3) 137799549 137803781(ext2)
CVE137870883(extl3) 137870963 137872829(ext1b) 137872834(ext1c) 137887787(ext2) 137890907
MSAM119890106(ext2) 119897919 119907162 119907458(ext1b) 119908552(extl3) 119908630 119909485
SCHU122862811 122862949(extl3) 122863823 122863835(ext1b) 122875957(ext2) 122881559
CUD121513315 121513674(ext2) 121521338 121521448(extl3) 121523384(ext1b) 121524170
ALAT119005988 119012419 119013096(extl3) 119016449(ext1b) 119017160 119017615(ext2)
ASTR137592938(ext2) 137601901 137607673(ext1c) 137607811(ext1b) 137613110(extl3) 137613916
MZE101464589 101467370(extl3) 101473582(ext2) 101479111 101482519 101486492
ONL100694061(extl3) 100695641(ext2) 100700775 100705583 100707723 109194193
OAU116309414 116312735(extl3) 116318909 116318948(ext1b) 116322583 116327190(ext2)
OLA101163398(ext2) 101163453(extl3) 101164181 101167217 101169374
OML112143494 112157675(extl3) 112160904(ext2) 112162700(ext1b) 112162739(ext1c)
CSAI133418595 133426387 133460500(ext1c) 133461261(ext1b) 133461580(ext2) 133464490(extl3)
XMA102217307 102217354 102230266 102234444(ext2) 102237506 102237533(extl3)
XCO114141516 114142777(ext2) 114155469 114156156 114158236(extl3) 114159116
XHE116716748 116718349(ext2) 116731149 116731796 116734009(extl3) 116734657
PRET103457265 103457379(extl3) 103462432(ext2) 103472886(ext1) 103473086 103478346
PFOR103131421 103133526(extl3) 103135121 103139431(ext2) 103151922 103154987 103155379(ext1)
PLAI106951280 106953583(ext1) 106958190(ext2) 106961006 106962939(extl3) 106964918
PMEI106907411 106911334(extl3) 106923397(ext1) 106926106(ext2) 106928852
GAF122821865(ext2) 122825094 122825437(extl3) 122831600 122843906(ext1b) 122844227(ext1c)
PPRL129354190(ext1b) 129357919 129367500 129369640(ext2) 129375284 129375314(extl3) 129375722(ext1c)
CVG107081098(extl3) 107082854 107085591(ext2) 107086154 107089629(ext1) 107094248 107094935
CTUL119771555(extl3) 119772289(ext1c) 119775297 119777081 119778046(ext1b) 119782724(ext2)
GMU124865747 124866743(ext2) 124879655(ext1c) 124879738(ext1b) 124881887 124882424(extl3)
NFU107377723(extl3) 107377760 107378775 107381443(ext2) 107394502 107394966
KMR108228674(ext2) 108232308 108233500(extl3) 108243943(ext1b) 108244864 108250176(ext1c)
ALIM106511501 106514225(ext1) 106525671(extl3) 106527530 106530767(ext2) 106532427 106535689
NWH119418590(extl3) 119418618 119425471 119425560(ext1c) 119427822(ext2)
AOCE111563665 111564587 111574611(ext2) 111580481 111583150(extl3) 111589114(ext1)
MCEP124998784(extl3) 125005111(ext2) 125016650 125019553(ext1b) 125019586
CSEM103378751(ext2) 103381137 103381243(extl3) 103388612(ext1) 103393992 103394040
POV109632177(ext1) 109636091(extl3) 109636768(ext2) 109639984 109642456 109643173 109644500
SSEN122772353(ext2) 122774807 122783726(extl3) 122784514 122786453 122786792
HHIP117758031 117758102(extl3) 117758296(ext2) 117770077 117770079(ext1b) 117776501
HSP118099325(extl3) 118099670 118109144(ext2) 118113668 118124559 118124711(ext1b)
PPLT128440274(ext2) 128449250 128459920 128460340(extl3) 128461233(ext1b) 128461234
SMAU118290069(extl3) 118290446 118291744(ext1b) 118292050 118302515(ext2) 118307214
LCF108873476 108888686 108889564(ext1b) 108889565 108889668 108889677 108891202
SDU111222995 111223271 111227735 111236334(extl3) 111237872 111238419(ext2)
SLAL111654812(ext2) 111658101 111661394(extl3) 111671857 111671874 111672565
XGL120784183 120786451(ext1b) 120786592(ext1c) 120788958 120789157(extl3) 120794269(ext2)
HCQ109514394(ext2) 109514670(extl3) 109518055 109518060 109523479 109529689(ext1)
SSCV125967040(ext2) 125975194 125986591(ext1b) 125986799 125990327(extl3) 125990392
SBIA133496212(extl3) 133496678 133498500(ext2) 133498505 133498911(ext1b) 133500493
PEE133395353 133395927(ext1c) 133399176(ext2) 133401231 133416635(extl3) 133416989
PTAO133468229 133468717(extl3) 133470740(ext1b) 133470770(ext2) 133471083(ext1c) 133479328
BPEC110153759 110156338 110164237(extl3) 110171534 110172856(ext2) 110173279
MALB109952487 109958190 109958643 109958685 109962352(extl3) 109965798(ext2) 109968834
BSPL114843138 114849466 114849866(extl3) 114852235(ext2) 114865978(ext1b) 114866303(ext1c)
SJO128357971(ext2) 128366364 128374174(ext1b) 128374740(ext1c) 128376753 128377073(extl3)
SASA100306779(ext1c) 100380322(ext2) 106570050 106571404 106571659 106588496 106588504 106594121 106597672 106607809 106608199
STRU115159705 115167097(ext2) 115173416 115173427 115174599 115174806 115175988 115175999 115187873 115187874 115192831
OTW112217339 112218009 112229926 112229932 112247034 112250171 112250478 112264222 112264884 112264892 121844920
OMY110487634 110488385 110496112(ext1b) 110496808(ext1c) 110506669 110511734 110522229 110522550 110526537 110529611 110529776
OGO123990750 123990909 123995089 123995375 124012587 124012858(ext1b) 124017649 124033638 124035622 124043635 124043639
ONE115107751 115107913 115112435(ext2) 115128292 115128299 115131708 115131715 115139163 115139415
OKI109866359 109866535 109881440 109882847 109884984 109888434 109900886 109901372 109903709 109907601 109907609
OKE118360328 118382370 118386898 118387120 118394191 118397690 118398284 118398500 118398659 118398931 118399209
SALP111954206 111954432 111955132 111955294 111955814 111955850 111969484 111972462 112069087
SNH120019129 120019504 120022446 120022523 120024042 120024563 120027266 120027289 120040883 120049131
CCLU121542569 121548546 121548927 121552392 121552579 121571473 121571482 121585943 121586367(ext1b) 121586374(ext1c) 123484405 123484718
ELS105005807 105017562(extl3) 105017786 105022258(ext2) 105023503 105027867
SFM108922050(ext1) 108924136(extl3) 108928562 108931808 108934682(ext2) 108940524
PKI111836091 111840708(ext2) 111841187(extl3) 111843930 111843931 111844061 111854291
AANG118215430(ext2) 118226079 118229494(extl3) 118230580 118233246(ext1c) 118233844
LOC102686314(extl3) 102688650 102688999(ext1) 102689027(ext2) 102698389
PSPA121294359 121303296 121308213 121313281 121314898 121315561 121316024(extl3) 121317487 121329636
ARUT117394872 117400267 117402503 117403267(extl3) 117411447 117412720 117414200 117432282 117435140 117964062
PSEX120516255(extl3) 120516821(ext1b) 120517016(ext2) 120517779 120526106
LCM102353460(EXT1) 102354369 102354854(EXTL1) 102361988(EXTL3) 102363354(EXT2)
CMK103174976(ext2) 103179627 103184956 103185802 103188516 121848587
RTP109914394 109926989(extl3) 109932300
CPLA122542486(extl3) 122549339 122558076(ext2) 122563602
HOC132811644 132824498(ext2) 132829949 132834029(extl3)
LERI129696566 129697007(extl3) 129697178 129705551(ext2) 129709842
PMRN116942528 116942588 116945182(EXTL3) 116945549(EXT2) 116951675
LRJ133340906 133349094 133349171 133351349(EXT2) 133353352(EXTL3)
BFO118404100 118404540 118408274
BBEL109479557 109480278 109483146
CIN100176235 100184170 100185120
SCLV120330866 120335452 120335699
SPU100893938 115918716 577995 585810
LPIC129258710
APLC110979510 110979551 110979555 110981069 110986223
ARUN117291505 117300762 117301143
AJC117120689 117120899 117122002
SKO100313593 100369934 100372539 102809744
DMEDmel_CG10117(ttv) Dmel_CG15110(botv) Dmel_CG8433(sotv)
DER6547292 6548926 6549168
DSE6609157 6609382 6609894
DSIDsimw501_GD11060(Dsim_GD11060) Dsimw501_GD11429(Dsim_GD11429) Dsimw501_GD25567(Dsim_GD25567)
DYADyak_GE12019 Dyak_GE13596 Dyak_GE14097
DAN6494354 6495892 6496091
DSR110177800 110178267 110184038
DPO4803873 4803961 4805743 6899125
DPE6590702 6590872 6601544 6601546
DMN108159562 108159662 108160133 117187784 117190510
DWI6640721 6640835 6646203
DGR6560884 6561214 6568946
DMODmoj_GI18912 Dmoj_GI20737 Dmoj_GI20872
DAZ108615183 108615817 108616969
DNV108652943 108653682 115564114 115564922
DHE111594305 111600127 111602550
DVI6624746 6627192 6635366
CCAT101453656 101460876 101461942
BOD106617525 106617537 106618671
BDR105228094 105228120 105228194
RZE108363084 108368905 108373058 108381813
AOQ129244452 129244561 129246422
TDA119675557 119678265 119679817 119686355
MDE101892286 101894872 101901385
SCAC106080711 106082419 106091369
LCQ111677016 111677307 111688369
LSQ119600640 119610135 119614574
GFS119640251 119641401 119642516
ECOE129940208 129944140 129950170
CLON129605324 129608535 129614279
HIS119655204 119655721 119656850
AGA1272189 1272657 1281488
ACOZ120949727 120952216 120956752
AARA120893798 120901724 120906198
AMER121589253 121593113 121599408
ASTE118503312 118505138 118509916
AFUN125760997 125764791 125768269
AMOU128297376 128306730 128309930
AALI118456637 118459545 118467462
AAG5566768 5578353 5578446
AALB109397881 109398955 109411435 109416900 109428863 115254192
ASUA134207535 134225952 134226639
CQUCpipJ_CPIJ009765 CpipJ_CPIJ012734 CpipJ_CPIJ016867
CPII120413984 120424304 120429091
CNS116339565 116340037 116349472
BCOO119068893 119078978 119081884
LLL129785989 129788595 129790538
PPAP129798673 129806250 129807718
AME408293 726216
ACER107997927 107999513 108001564
ALAB122711813 122711993 122714818
ADR102678944 102680766
AFLR100867904 100871709
BIM100741317 100744382 105680701
BBIF117205178 117211962 117214192
BVK117232255 117239137 117243560
BVAN117156137 117164164 117166073
BHUN126866330 126866545 126875259
BTER100643223 100650849 105666123
BAFF126925000 126926220 126928914
BPYO122571366 122571851 122577021
BPAS132908765 132909178 132915143
FVI122528253 122533497 122535403
CCAL108622677 108622898 108627221
OBB114871565 114871663 114871977 114880970
OLG117601667 117605886 117607017
MGEN117219922 117220187 117224160
NMEA116429461 116432549
CGIG122399622 122400966 122404430
SOC105195910 105198634 105200907
MPHA105835292 105838726 105839250
AEC105150811 105153382 105154628
ACEP105619491 105620069 105627211
PBAR105425236 105427034 105433557
VEM105564271 105564746 105564962
HST105181013 105188235 105188784
DQU106742285 106745718 106750617
CFO105251656 105253055 105253243
FEX115234785 115235169 115240513
LHU105673709(sotv) 105674049(botv) 105675813(ttv)
PGC109853827 109854839 109863645
OBO105287638 105288161
PCF106786799 106790860 106791047
PFUC122518599 122522139 122523426
VPS122629883 122631850 122638200
VCRB124425186 124425504 124426496
VVE124946884 124949236 124952716
NVI100114642 100120177 100121031
CSOL105364815 105365204 105366129
TPRE106651356 106653398
LHT122503992 122507693 122511606
LBD127278652 127283446 127289685
MDL103569026 103578696 103580382
CGLO123261632 123268665 123275072
FAS105262784 105265574 105268060
DAM107040372 107041901 107043534
AGIF122847424 122851929 122854354
CINS118063990 118067431 118074555
VCAN122407576 122409842 122415563
CCIN107262845 107267679 107268133
DSM124408566 124411164
NPT124213539(ttv) 124217576(sotv) 124220681
NFB124177902 124180268 124182380
NLO107218971 107220093 107220580
NVG124301106 124303405 124304715
AROA105685258 105686924 105688324
TCA657388 659287 663383
DPA109537502 109537981 109539467
SOY115875099 115881569 115885155
AGRG126743488 126743580 126748888
ATD109596360 109599451 109609672
CSET123311160 123316160 123321334
AGB108912068 108912966 108913506
LDC111502043 111503945 111509249
DVV114336209 114338127 114340457
NVL108557086 108557670 108558174 108567151
DCOR135795978(botv) 135797169(ttv)
APLN108735767 108740927 108743766
PPYR116163081 116164508 116166831 116171124
OTU111414203 111419426 111427848
BMOR101736061 101741346 101742984
BMAN114247002 114248987 114249440
MSEX115440710 115448364 115450427
DPLKGM_203672 KGM_208641 KGM_214517
BANY112045658 112046889 112047335
MJU123864564 123870585 123875294
NIQ126771756 126772326 126778519
VCD124531698 124539066 124543422
MCIX123658419 123664598 123669423
PMAC106708978 106709701 106712471
PPOT106100685 106105805 106107976
PXU106117396 106121928 106124397
BPHI137926552(ttv) 137929330(botv) 137933708(sotv)
PRAP110993283 111000541 111003256
PBX123713481 123716512 123717819
PNAP125049662 125056161
ZCE119829569 119830202 119834064
CCRC123696746 123704496 123705704
LSIN126966570 126971154 126974418
AAGE121729316 121730210 121733524
HAW110370155 110374076(ttv) 110376090
HZE124631134 124633761 124641177
TNL113493550 113496594 113505944
SLIU111353115 111355951 111357626
OFU114349767 114352184 114352413
ATRA106132882 106135529 106137347 106138417
GMW113509908 113518447 113522469
PXY105388581 105394758
PGW126371220 126377613 126381854
LGLY125225474 125229496 125240565
CSTB134744564 134754827 134755872
CFEL113365782 113366316 113369841 113369842 113370457 113370853
CCRN123293883 123299680 123302491
API100164685 100167784 100167795
DNX107161983 107163206 107174001
AGS114120422 114122118 114131437
RMD113556372 113556757 113560806
ACOO126835201 126840666 126846336
DVT126893490 126905173 126906273
BTAB109030556 109034604 109035894
DCI103505288 103516295
CLEC106672266 106673227 106674189
HHAL106678975(sotv) 106679847(botv) 106681771
NLU111049614 111055975 111056777
HVI124359848 124360669 124362624 124373510
MQU128989954 128991922 128992456 128993264
PHUPhum_PHUM455050 Phum_PHUM488440 Phum_PHUM490250
FOC113203130 113211216 113216463
TPAL117650602 117652175 117652466
ZNE110827878 110831848 110831980
CSEC111866806 111866884 111872464
SGRE126297625 126335001 126335121 126352265
BROR134531986 134535068 134538741
IEL124154440 124157943 124160634
FCD110846056 110847436 110859221
DPXDAPPUDRAFT_218850 DAPPUDRAFT_304945 DAPPUDRAFT_307216
DMK116933567 116933752 116934955
DPZ124312788 124328499 124337515 124340498
PVM113802032 113819647 113819966 113824640
PJA122245774 122263365 122264403
PCHN125027164 125032085 125036743
PMOO119590898 119592442 119596794
HAME121864489 121869478 121874923
PCLA123758376 123762596 123769944
CQD128699795 128705176
PTRU123501535 123501664 123501943
ESN126984445 127000928 127005043 127005282
MNZ135194969 135223631 135224548
MRJ136831668 136842590(sotv) 136848824(botv)
HAZT108665016 108671440 108677950
EAF111696021 111700775 111718430
LSM121116393 121117496 121121323
TCF131883056 131883327 131886011
PPOI119094444 119094445 119101712 119101717 119101720 119102599
DSV119457583 119461512 119461515 119464578
RSAN119374094 119396015 119402119
RMP119165413 119167082 119174327
VDE111246358 111248228 111251828
VJA111265185 111268050 111268602
TUT107361403 107366477 107367244 107371591 107371607
DPTE113789732 113795874 113796479
DFR124491080 124491918 124498786
CSCU111630346 111639700 111639960
CVS136968529(botv) 136972765(sotv) 136988493(ttv)
PTEP107437365 107450714 107455291
ABRU129960529 129972503 129988529
UDV129230506 129231603 129235240
SDM118185853 118192709 118200215
LPOL106458350 106460090 106471727 106473945 106478475
PMEO129586373 129588086 129596158
CELCELE_F12F6.3(rib-1) CELE_K01G5.6(rib-2)
CBRCBG_18318(Cbr-rib-2)
CRQGCK72_010410
NAINECAME_01875 NECAME_03535 NECAME_04728
BMYBM_BM10349(Bma-rib-2) BM_BM3322(Bma-rib-1) BM_BM4732(Bm4732)
LOALOAG_05822 LOAG_07208 LOAG_08703
TSPTsp_02636 Tsp_04346
HROHELRODRAFT_119925 HELRODRAFT_186788 HELRODRAFT_83262
LGILOTGIDRAFT_124977 LOTGIDRAFT_137450 LOTGIDRAFT_199269
PVUL126808726 126824087 126831214
PCAN112561913 112562383 112565643
BGT106055537 106058680 106070127
GAE121372488 121376972 121377129
HRF124114597 124138230 124149462
HRJ124256095 124270731 124276925 124282773
HASI137277473 137278551 137286532
CRG105324710 105325442 105341576
CANU128179477 128181295 128183294
CVN111099932 111104029 111104189 111126456
OED125647197 125674228 125683894
MYI110442614 110443488 110451580
PMAX117316492 117317139 117326975
MCAF127725165 127732068 127732091
MMER123539606 123540528 123552181
RPHI132715401 132733114 132752103
DPOL127848267 127850329 127857791 127877490
MAEA128205503 128205603 128238651
OBI106867259 106868410 106873155 106874784
OSN115223438 115223625 115223691 115223714 115230884 115231411
LJP135463576 135463627 135463785 135464064
LAK106152057 106155252 106175986 106181741
SMMSmp_073220 Smp_146320.1 Smp_172060
SHXMS3_00006818(EXT2_1) MS3_00010111(EXTL3_1)
OVIT265_05866 T265_05932 T265_06473 T265_07036
EGLEGR_02934 EGR_06675 EGR_08543
LLON135487508 135502896 135502955
NVE5504655 5505005 5510789
EPA110234330 110240280 110241454 110241460
ATEN116293188 116298104 116307177
ADF107336652 107336815 107341811 107358713
AMIL114957442 114961284 114970312
PDAM113666284 113669827 113677366
SPIS111325684 111326534 111336973
DGT114527489 114528496 114537265
XEN124438051 124456299 124457859
HMG100208615 100212044 100212160
HSY130646977 130647744 130654077
RES135681776 135689667 135689836
TADTRIADDRAFT_1026 TRIADDRAFT_24279
AQU100636774 100640795 100641175
SMOSELMODRAFT_23945 SELMODRAFT_24030
PPP112279610 112280248 112280650 112281934 112282628 112290993 112294684
FGRFGSG_12261
FPUFPSE_06328
FVRFVEG_11257
FOXFOXG_13828
NHENECHADRAFT_84083
MBRMONBRDRAFT_25145
SREPTSG_07269 PTSG_09573 PTSG_10121
ACANACA1_335890 ACA1_393390
PTIPHATRDRAFT_11259
FCYFRACYDRAFT_160829 FRACYDRAFT_234481
TPSTHAPSDRAFT_263396
GTTGUITHDRAFT_143314
 » show all
Reference
1  [PMID:11390981]
  Authors
Kim BT, Kitagawa H, Tamura J, Saito T, Kusche-Gullberg M, Lindahl U, Sugahara K
  Title
Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
  Journal
Proc Natl Acad Sci U S A 98:7176-81 (2001)
DOI:10.1073/pnas.131188498
  Sequence
[hsa:2134]
Reference
2  [PMID:11121397]
  Authors
Kitagawa H, Egusa N, Tamura JI, Kusche-Gullberg M, Lindahl U, Sugahara K
  Title
rib-2, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes encodes a novel alpha1,4-N-acetylglucosaminyltransferase involved in the biosynthetic initiation and elongation of heparan sulfate.
  Journal
J Biol Chem 276:4834-8 (2001)
DOI:10.1074/jbc.C000835200
  Sequence
Reference
3  [PMID:11256613]
  Authors
Senay C, Lind T, Muguruma K, Tone Y, Kitagawa H, Sugahara K, Lidholt K, Lindahl U, Kusche-Gullberg M.
  Title
The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis.
  Journal
EMBO Rep 1:282-6 (2000)
DOI:10.1093/embo-reports/kvd045
  Sequence
[bta:281151]
Reference
4  [PMID:9756849]
  Authors
Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K
  Title
The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.
  Journal
J Biol Chem 273:26265-8 (1998)
DOI:10.1074/jbc.273.41.26265
  Sequence
[bta:281151]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.224
IUBMB Enzyme Nomenclature: 2.4.1.224
ExPASy - ENZYME nomenclature database: 2.4.1.224
BRENDA, the Enzyme Database: 2.4.1.224
CAS: 336193-98-7
LinkDB

KEGG   REACTION: R10139
Entry
R10139                      Reaction                               
Definition
G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP
Equation
Enzyme
Pathway
rn00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.224
     R10139  G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.4.1.224
   R07334  beta-D-Glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan <=> N-Acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminylproteoglycan
    R10139
Glycosyltransferase reactions [BR:br08203]
 N-Acetylglucosaminyltransferase reactions
  R10139  GlcNAc a1-4 GlcA
Orthology
K02366  glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]
K02367  glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]
LinkDB

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