Entry |
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Symbol |
NDST1
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Name |
heparan sulfate N-deacetylase/N-sulfotransferase NDST1 [EC:3.5.1.- 2.8.2.8]
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Pathway |
map00534 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
|
Module |
M00059 | Glycosaminoglycan biosynthesis, heparan sulfate backbone |
|
Reaction |
R13046 | poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl] amidohydrolase |
R13047 | 3'-phosphoadenylyl-sulfate:heparosan-D-glucuronate N-sulfonotransferase |
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Disease |
H00768 | Autosomal recessive intellectual developmental disorder |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
K02576 NDST1; heparan sulfate N-deacetylase/N-sulfotransferase NDST1
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases
K02576 NDST1; heparan sulfate N-deacetylase/N-sulfotransferase NDST1
Enzymes [BR:ko01000]
2. Transferases
2.8 Transferring sulfur-containing groups
2.8.2 Sulfotransferases
2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase
K02576 NDST1; heparan sulfate N-deacetylase/N-sulfotransferase NDST1
Glycosyltransferases [BR:ko01003]
Unclassified
Sulfotransferases
K02576 NDST1; heparan sulfate N-deacetylase/N-sulfotransferase NDST1
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Aikawa J, Grobe K, Tsujimoto M, Esko JD |
Title |
Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. |
Journal |
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Sequence |
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Reference |
|
Authors |
Pikas DS, Eriksson I, Kjellen L |
Title |
Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns. |
Journal |
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LinkDB |
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