Entry Name D-sedoheptulose-7-phosphate isomerase;
Class Isomerases;BRITE hierarchy
Sysname D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase
Reaction(IUBMB) D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate [RN:
R09768 ]
Reaction(KEGG) Substrate D-sedoheptulose 7-phosphate [CPD:
C05382 ]
Product D-glycero-D-manno-heptose 7-phosphate [CPD:
C19882 ]
Comment In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
History EC 5.3.1.28 created 2010
Pathway ec00540 Lipopolysaccharide biosynthesis
Orthology K03271 D-sedoheptulose 7-phosphate isomerase
Genes ECOO : ECRM13514_0234(gmhA)
ECOH : ECRM13516_0233(gmhA)
ELR : ECO55CA74_01215(gmhA)
ECW : EcE24377A_0254(gmhA)
EDJ : ECDH1ME8569_0210(lpcA)
ECOI : ECOPMV1_00254(gmhA)
SEM : STMDT12_C03100(gmhA)
SETC : CFSAN001921_15850(gmhA)
SEEN : SE451236_07580(gmhA)
SENH : CFSAN002069_07590(gmhA)
SEEH : SEEH1578_10655(gmhA)
SENJ : CFSAN001992_09640(gmhA)
SEEC : CFSAN002050_08150(gmhA)
SEEB : SEEB0189_017745(gmhA)
SENC : SEET0819_08565(gmhA)
REE : electrica_04105(gmhA)
RTG : NCTC13098_06007(gmhA)
HDE : HDEF_0185 HDEF_2106(lpcA)
CLAP : NCTC11466_03685(gmhA)
KGO : CEW81_08850 CEW81_19925
KIE : NCTC12125_02799(gmhA)
HED : TPER_HE00002_II(gmhA)
AHN : NCTC12129_01027(gmhA)
METY : MRY16398_45490(gmhA)
PTF : PROFFT_A_01120(gmhA)
PSHI : SAMEA2665130_0547(gmhA)
YPG : YpAngola_A3320(gmhA1)
YPI : YpsIP31758_3170(gmhA1)
YPQ : DJ40_1347(gmhA) DJ40_1474(gmhA)
YPU : BZ21_129(gmhA) BZ21_255(gmhA)
YPR : BZ20_1034(gmhA) BZ20_1163(gmhA)
YPC : BZ23_406(gmhA) BZ23_531(gmhA)
YMO : HRD69_10265(lpcA) HRD69_11005
YAS : N0H69_17360 N0H69_20165(lpcA)
SMW : SMWW4_v1c08750(lpcA)
SERS : SERRSCBI_04175(gmhA)
SFJ : SAMEA4384070_0979(gmhA)
SOF : NCTC11214_00551(gmhA_1) NCTC11214_00552(gmhA_2)
SSAR : SSARUM_000829(lpcA)
FSM : CCS41_00960 CCS41_07100
SERA : Ser39006_007630(gmhA)
PAQU : DMB82_0004920(lpcA)
PARL : PEC302110_30520(lpcA)
DIC : Dpoa569_002998(lpcA)
EHD : ERCIPSTX3056_362(gmhA)
BAPF : BUMPF009_CDS00346(gmha)
BAPG : BUMPG002_CDS00347(gmha)
BAPU : BUMPUSDA_CDS00346(gmha)
BAPW : BUMPW106_CDS00346(gmha)
TPTY : NCTC11468_02954(gmhA)
PLU : plu1193(lcpA) plu4823(wblX)
PLUM : A4R40_05895(gmhA) A4R40_23990
PHEI : NCTC12003_00877(gmhA)
PRJ : NCTC6933_00960(gmhA)
MWI : MNY66_03255(lpcA) MNY66_17770
LRI : NCTC12151_01096(gmhA)
HIC : NTHIC486_01563(gmhA)
HPIT : NCTC13334_01181(gmhA)
HHZ : NCTC10839_01132(gmhA)
HAEG : NCTC8502_01308(gmhA)
PDAG : 4362423_00226(gmhA_1)
ADP : NCTC12871_00180(gmhA)
ALIG : NCTC10568_00556(gmhA)
ASEG : NCTC10977_00961(gmhA)
AVT : NCTC3438_02148(gmhA)
RPNE : NCTC8284_03177(gmhA_2)
PAET : NCTC13378_00037(gmhA_1)
VSI : MTO69_00670 MTO69_03260(lpcA)
VAF : D1115_04175 D1115_23005
VSR : Vspart_00206(gmhA_1) Vspart_02490(gmhA_2)
VZI : G5S32_11110(lpcA) G5S32_14890
VPL : SA104470976_00581(gmhA)
VJP : NP165_09510(lpcA) NP165_18365
VRU : RND59_05060 RND59_10330(lpcA)
PGB : H744_1c0467 H744_2c0977 H744_2c2397
PGH : FH974_03390(lpcA) FH974_09835
PAEB : NCGM1900_2255(gmhA)
PRE : PCA10_10650(gmhA) PCA10_12810(gmhA)
PPSE : BN5_3127(gmhA1) BN5_3475(gmhA3)
PFUW : KF707C_12480 KF707C_9910
PFV : Psefu_2943 Psefu_3578
PVD : CFBP1590__1160(gmhA)
PPRC : PFLCHA0_c50490(gmhA)
PMUD : NCTC8068_04371(gmhA)
PFW : PF1751_v1c08940(gmhA)
PLUL : FOB45_10320 FOB45_11330(lpcA)
PPUU : PputUW4_04518(gmhA)
PSET : THL1_1114 THL1_1355
PALL : UYA_04460 UYA_05775 UYA_23040
POJ : PtoMrB4_12330(gmhA_1) PtoMrB4_41030(gmhA_2)
PLAL : FXN65_04945 FXN65_06045(lpcA)
PSEJ : HNQ25_18375(lpcA) HNQ25_19710
PKH : JLK41_04760 JLK41_06425(lpcA)
PTY : JWV26_15540 JWV26_16690(lpcA)
PMAO : PMYSY11_1105(diaA) PMYSY11_2854(lpcA)
PWZ : J7655_04275 J7655_05840(lpcA)
PTW : TUM18999_13280(gmhA_1) TUM18999_44450(gmhA_2)
PTAE : NCTC10697_00845(gmhA)
PHF : NLY38_04600 NLY38_06185(lpcA)
PSOA : PSm6_05620(gmhA_1) PSm6_32660(gmhA_2)
PCHE : QYM18_12380 QYM18_13795(lpcA)
PSLP : BHQ29_16275 BHQ29_17555
MALL : PBN92_03490 PBN92_04055
MSHE : MAALD49_07740(gmhA) MAALD49_08830(gmhA)
PSPI : PS2015_2135 PS2015_2311
PRR : AT705_15655 AT705_18665
PLZ : S4054249_04720 S4054249_06285
PPIS : B1L02_02440 B1L02_10955
PSEN : PNC201_14510(gmhA1)
PXI : J5O05_12875 J5O05_14480
ALTR : BM528_01585 BM528_09855
PMAW : MACH26_32980(gmhA_2)
CEB : B0D95_10815 B0D95_15715
CELL : CBR65_08330 CBR65_10175
CEG : D0C16_11640 D0C16_15815(gmhA)
MARQ : MARGE09_P2120 MARGE09_P2718
PAQM : E0F26_09295 E0F26_12090
CBU : CBU_0674 CBU_1743(gmhA)
ALG : AQULUS_05160(gmhA_1) AQULUS_05240(gmhA_2)
ASIP : AQUSIP_18130(gmhA_2)
LLG : 44548918_02741(yraO)
LJR : NCTC11533_02903(yraO)
LCJ : NCTC11976_00649(yraO)
LWA : SAMEA4504053_3504(gmhA)
LSS : NCTC12082_02016(yraO)
LADL : NCTC12735_00209(yraO)
LANT : TUM19329_35280(gmhA)
MDN : JT25_010430 JT25_014895
METL : U737_03415 U737_04490 U737_23090
MPAD : KEF85_11820 KEF85_15985
MEEP : JWZ98_00775 JWZ98_02705
MPSY : CEK71_04775 CEK71_12700
MSZE : MSZNOR_2834(diaA) MSZNOR_3943(gmhA)
MMOB : F6R98_01350 F6R98_03555 F6R98_19110
MEIN : methR_P2382 methR_P2887 methR_P3627
MISZ : MishRS11D_00760(gmhA1) MishRS11D_19310(gmhA)
MESL : KKZ03_07200 KKZ03_07985 KKZ03_15200
HTR : EPV75_03145 EPV75_08910
HMAR : HVMH_0806(gmhA_1) HVMH_1888(gmhA_2)
THIO : AYJ59_01430 AYJ59_10660
TIB : THMIRHAM_04660(gmhA)
TSE : THMIRHAS_20010(gmhA1)
TZO : THMIRHAT_05890(gmhA)
TANI : J8380_02630 J8380_02715
NHL : Nhal_0473 Nhal_1320 Nhal_1358
NWR : E3U44_02110 E3U44_16485
TVI : Thivi_2615 Thivi_4046
TFRI : Thiofri_04186(gmhA1)
TWG : Thiowin_03890(gmhA1)
TNI : TVNIR_2698(gmhA_[H])
EPS : L0Y14_04155 L0Y14_12655
THIC : TspCOW1_33000(gmhA)
HCH : HCH_01840(gmhA1) HCH_05896(gmhA2) HCH_06182(gmhA3)
HAHE : ENC22_04490 ENC22_21575 ENC22_26655
HAHH : O5O45_17215 O5O45_29340 O5O45_30705
HBE : BEI_1198(gmhA1) BEI_1278(gmhA2)
HAXI : HAALTHF_32290n(gmhA)
HAAH : HALA3H3_950065(gmhA)
KMA : B9H00_15410 B9H00_15835
ALCA : ASALC70_01166(gmhA)
TOR : R615_06690 R615_13205
BSAN : CHH28_07270 CHH28_17915
NCU : F0U83_04445 F0U83_10925
