KEGG ORTHOLOGY: K03460

ORTHOLOGY: K03460

Entry

K03460                      KO

Symbol

SLCO1A

Name

solute carrier organic anion transporter family, member 1A

Pathway

map04976

Bile secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K03460  SLCO1A; solute carrier organic anion transporter family, member 1A
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K03460  SLCO1A; solute carrier organic anion transporter family, member 1A
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC21/ASLCO: Organic anion transporter
   K03460  SLCO1A; solute carrier organic anion transporter family, member 1A

Other DBs

GO:

0008514

TC:	2.A.60.1.1 2.A.60.1.3 2.A.60.1.4 2.A.60.1.6 2.A.60.1.14

Genes

HSA:	6579(SLCO1A2)

PTR:	473385(SLCO1A2)

PPS:	100974966(SLCO1A2)

GGO:	101128184(SLCO1A2)

PON:	100451125(SLCO1A2)

PPYG:

129009336(SLCO1A2)

NLE:	100585375(SLCO1A2)

HMH:	116472759(SLCO1A2)

SSYN:

129483276(SLCO1A2)

MCC:	705434(SLCO1A2)

MCF:	101925822(SLCO1A2)

MTHB:

126930519

MNI:	105469869(SLCO1A2)

CSAB:

103218732(SLCO1A2)

CATY:

105585068(SLCO1A2)

PANU:

101004941

TGE:	112634356(SLCO1A2)

MLEU:

105531535(SLCO1A2)

RRO:	104660883(SLCO1A2)

RBB:	108539717(SLCO1A2)

TFN:	117090411(SLCO1A2)

PTEH:

111540645(SLCO1A2)

CANG:

105520977(SLCO1A2)

CJC:	118144203(SLCO1A2)

SBQ:	101038115(SLCO1A2)

CIMI:

108300242(SLCO1A2)

ANAN:

105705764(SLCO1A2)

CSYR:

103268270(SLCO1A2)

MMUR:

105882812(SLCO1A2)

LCAT:

123639946(SLCO1A2)

PCOQ:

105807619(SLCO1A2)

OGA:	100947570(SLCO1A2)

MMU:	108096(Slco1a5) 28248(Slco1a1) 28250(Slco1a4) 28254(Slco1a6) 435927(Slco1a7) 625716(Slco1a8)

MCAL:

110287587 110287588 110287589 110287591 110288502 110296298(Slco1a2)

MPAH:

110314589 110314590 110314591(Slco1a2) 110314614 110315704

RNO:	170698(Slco1a4) 50572(Slco1a1) 80899(Slco1a3) 80900(Slco1a5) 84608(Slco1a6)

MCOC:

116098421 116098422 116098423 116098425 116099754 116099756

ANU:	117715179 117715196 117715210 117715212 117715213 117715223 117715352 117715809

MUN:	110541752 110542238 110552204 110564253 110564560 110564562

CGE:	100771487 100771780

MAUA:

101831491 101831756 101832023 106020748

PROB:

127213110 127213114

PLEU:

114700295(Slco1a2) 114700296

MORG:

121434013 121434032 121434378 121435051 121440255 121441010

MFOT:

126497311 126497313 126497315 126497316 126497319 126497335

AAMP:

119806699 119806700 119806701 119806703 119807729 119808139

NGI:	103748802(Slco1a2)

HGL:	101702734(Slco1a2)

CPOC:

100714302(Slco1a2)

CCAN:

109682207(Slco1a2)

DORD:

105992236(Slco1a2)

PLOP:

125342864(Slco1a2)

NCAR:

124983536

MMMA:

107152768(Slco1a2)

OCU:

100355617

OPI:	101530394(SLCO1A2)

TUP:	102475680(SLCO1A2)

GVR:	103601702(SLCO1A2)

CFA:	403520(SLCO1A2)

CLUD:

112665478(SLCO1A2)

VVP:	112917229(SLCO1A2)

VLG:	121480028(SLCO1A2)

NPO:	129505573(SLCO1A2)

AML:	100481027(SLCO1A2)

UMR:	103677809(SLCO1A2)

UAH:	113257824(SLCO1A2)

UAR:	123781770(SLCO1A2)

ELK:

111142208

LLV:

125107724

MPUF:

101689315(SLCO1A2)

MNP:	132019529(SLCO1A2)

MLK:	131838978(SLCO1A2)

NVS:	122891853(SLCO1A2)

ORO:	101383656(SLCO1A2)

EJU:	114200910(SLCO1A2)

ZCA:	113923173(SLCO1A2)

MLX:	118025600(SLCO1A2)

NSU:	110580913(SLCO1A2)

LWW:	102731119(SLCO1A2)

FCA:	101087585(SLCO1A2)

PYU:	121038844(SLCO1A2)

PCOO:

112867566(SLCO1A2)

PBG:	122474013(SLCO1A2)

PVIV:

125170375(SLCO1A2)

LRUF:

124502310

PTG:	102970461(SLCO1A2)

PPAD:

109268691(SLCO1A2)

PUC:

125920155

AJU:

106977175

HHV:	120225386(SLCO1A2)

BTA:	282472(SLCO1A2)

BOM:	102287227(SLCO1A2)

BIU:	109559601(SLCO1A2)

BBUB:

102404154(SLCO1A2)

BBIS:

105000206(SLCO1A2)

CHX:	102190858(SLCO1A2)

OAS:	101119972(SLCO1A2)

BTAX:

128047741(SLCO1A2)

ODA:	120858922(SLCO1A2)

CCAD:

122423959(SLCO1A2)

MBEZ:

129535898(SLCO1A2)

SSC:	397534(SLCO1A2)

CFR:	102510851(SLCO1A2)

CBAI:

105062278(SLCO1A2)

CDK:	105096488(SLCO1A2)

VPC:	102545775(SLCO1A2)

BACU:

103005995(SLCO1A2)

BMUS:

118902599(SLCO1A2)

LVE:	103078899(SLCO1A2)

OOR:	101288567(SLCO1A2)

DLE:	111176829(SLCO1A2)

PCAD:

102988065(SLCO1A2)

PSIU:

116760565(SLCO1A2)

NASI:

112391765(SLCO1A2)

ECB:	100034162(SLCO1A2)

EPZ:	103560771(SLCO1A2)

EAI:	106825551(SLCO1A2)

MYB:	102253001(SLCO1A2)

MYD:	102772718(SLCO1A2)

MMYO:

118651847(SLCO1A2)

MLF:	102440703(SLCO1A2)

MDT:	132227359(SLCO1A2)

PKL:	118730829(SLCO1A2)

EFUS:

103285139(SLCO1A2)

MNA:	107525276(SLCO1A2)

DRO:	112318471(SLCO1A2)

SHON:

118978354(SLCO1A2)

AJM:	119042844(SLCO1A2)

PDIC:

114513371(SLCO1A2)

PHAS:

123812342(SLCO1A2)

MMF:	118623958(SLCO1A2)

PPAM:

129084986(SLCO1A2)

HAI:	109378481(SLCO1A2)

RFQ:	117029110(SLCO1A2)

PALE:

102889571(SLCO1A2)

PGIG:

120618379(SLCO1A2)

PVP:	105306547(SLCO1A2)

RAY:	107508569(SLCO1A2)

MJV:	108398368(SLCO1A2)

TOD:	119247649(SLCO1A2)

SARA:

101537924(SLCO1A2)

SETR:

126022854(SLCO1A2)

LAV:	100657323(SLCO1A2)

ETF:	101648807(SLCO1A2)

DNM:	101429744(SLCO1A2)

MDO:	100011589(SLCO1A2)

GAS:	123250619(SLCO1A2)

SHR:	100918916(SLCO1A2)

AFZ:

127564196

PCW:	110213752(SLCO1A2)

TVP:	118852188(SLCO1A2)

OAA:

100084385

GGA:	418190(SLCO1A2)

PCOC:

116231814

MGP:	100540976(SLCO1A2)

CJO:

107316629

TPAI:

128084576(SLCO1A2)

LMUT:

125700908(SLCO1A2)

NMEL:

110396017

APLA:

101802312

ACYG:

106045459

CATA:

118244985(SLCO1A2)

AFUL:

116495977(SLCO1A2)

TGU:

100217663

LSR:	110482605(SLCO1A2)

SCAN:

PMOA:

OTC:

PRUF:

GFR:	102041190(SLCO1A2)

FAB:	101815919(SLCO1A2)

OMA:

130254376

PHI:

102109127

PMAJ:

107205143

CCAE:

111923307(SLCO1A2)

CCW:

104692282

CBRC:

103617295(SLCO1A2)

ETL:	114062610(SLCO1A2)

ZAB:

102063879

ZLE:

135459031

ACHL:

103799368(SLCO1A2)

SVG:	106849463(SLCO1A2)

MMEA:

130575556

HRT:

120752212

SATI:

136361515

FPG:	101920719(SLCO1A2)

FCH:	102049625(SLCO1A2)

CCRI:

104168434(SLCO1A2)

NNT:	104410161(SLCO1A2)

SHAB:

115605234

ACUN:

113488312(SLCO1A2)

TALA:

104358304(SLCO1A2)

ACHC:

115352813

HALD:

104311268(SLCO1A2)

HLE:	104830898(SLCO1A2)

AGEN:

126047690

GCL:

127017776

CSTI:

104560240(SLCO1A2)

LDI:

104350772

MNB:	103774772(SLCO1A2)

DPUB:

104305333

AVIT:

104270270(SLCO1A2)

BRHI:

104497325

EGZ:	104135125(SLCO1A2)

NNI:	104017959(SLCO1A2)

PCAO:

104040015(SLCO1A2)

PADL:

103924338(SLCO1A2)

AFOR:

103898681(SLCO1A2)

FGA:	104072334(SLCO1A2)

GSTE:

104263120(SLCO1A2)

CLV:

102084578

MUI:	104542384(SLCO1A2)

PGUU:

104471343(SLCO1A2)

PLET:

104616645(SLCO1A2)

EHS:	104506614(SLCO1A2)

CMAC:

104474149(SLCO1A2)

CUCA:

104065624(SLCO1A2)

TEO:	104374184(SLCO1A2)

BREG:

104632163(SLCO1A2)

OHA:	104338093(SLCO1A2)

ACAR:

104518751

CPEA:

104393452

CVF:	104281633(SLCO1A2)

RTD:

128909255

AAM:	106488438(SLCO1A2)

AROW:

112966599

NPD:	112944171 112944382

DNE:

112978912

SCAM:

104142133(SLCO1A2)

ASN:	102375408(SLCO1A2)

AMJ:	106736949(SLCO1A2)

CPOO:

109316411(SLCO1A2)

GGN:	109296282(SLCO1A2)

PSS:	102458523(SLCO1A2)

CMY:

102942644

CCAY:

125625261

DCC:

119859427

CPIC:

101953438(SLCO1A2)

TST:

117883193

CABI:

116834147

MRV:

120372961

ACS:	100554620(slco1a2)

ASAO:

132775732(SLCO1A2)

PVT:	110088801(SLCO1A2)

SUND:

121931223(SLCO1A2)

PBI:

103061869

PMUR:

107293892

CTIG:

120303410(SLCO1A2)

TSR:	106556516(SLCO1A2)

PGUT:

117680105

APRI:

131202410

PTEX:

113442909(SLCO1A2)

NSS:	113419038(SLCO1A2)

VKO:	123034656(SLCO1A2)

PMUA:

114605754 114605812

PRAF:

128422860

ZVI:	118091332(SLCO1A2)

HCG:	128328437 128328521

STOW:

125435316 125435317

EMC:	129335957(SLCO1A2)

XLA:	398783(slco1a2.L)

XTR:	100124879(slco1a2)

NPR:

RTEM:

BBUF:

BGAR:

MUO:

GSH:	117367231(SLCO1A2)

BGT:

106062159

» show all

Reference

PMID:14579113

Authors

Hagenbuch B, Meier PJ

Title

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.

Journal

Pflugers Arch 447:653-65 (2004)
DOI:10.1007/s00424-003-1168-y

Sequence

[hsa:6579]

LinkDB

ORTHOLOGY: K05043

Entry

K05043                      KO

Symbol

SLCO1B

Name

solute carrier organic anion transporter family, member 1B

Pathway

map04976

Bile secretion

Disease

H00208

Hyperbilirubinemia

H02057

Rotor syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K05043  SLCO1B; solute carrier organic anion transporter family, member 1B
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05043  SLCO1B; solute carrier organic anion transporter family, member 1B
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC21/ASLCO: Organic anion transporter
   K05043  SLCO1B; solute carrier organic anion transporter family, member 1B

Other DBs

GO:

0015347

TC:	2.A.60.1.5 2.A.60.1.8 2.A.60.1.12

Genes

HSA:	10599(SLCO1B1) 115072896(SLCO1B3-SLCO1B7) 28234(SLCO1B3)

PTR:	112204985 134807488 465331(SLCO1B1) 749254

PPS:	100976318(SLCO1B1) 100976982 106634354

GGO:	101126367(SLCO1B3) 101127810(SLCO1B1) 134756555

PON:	100447113 100448597 134759462

PPYG:

129009440(SLCO1B1) 129009441 129010613

NLE:	100584491(SLCO1B3) 100585039(SLCO1B1)

HMH:	116472756(SLCO1B3) 116472758

SSYN:

129481899 129483277 129483278

MCC:	100430432(SLCO1B7) 574354(SLCO1B3) 705308(SLCO1B1)

MCF:	102136593(SLCO1B3) 102137347

MTHB:

126930507

MNI:	105469870(SLCO1B1) 105469871(SLCO1B7) 105481244(SLCO1B3)

CSAB:

103218728(SLCO1B3) 103218729(SLCO1B7) 103218730(SLCO1B1)

CATY:

105585071(SLCO1B1) 105585072(SLCO1B7) 105585073(SLCO1B3)

PANU:

101003890(SLCO1B3) 101004239 101004585

TGE:	112634354(SLCO1B3) 112634355(SLCO1B1) 112634357(SLCO1B7)

MLEU:

105531531(SLCO1B3) 105531532(SLCO1B7) 105531533(SLCO1B1)

RRO:	104660880(SLCO1B3) 104660881(SLCO1B1)

RBB:	108539718(SLCO1B1) 108539743(SLCO1B3)

TFN:	117090412 117090416(SLCO1B3)

PTEH:

111540569(SLCO1B1) 111552081(SLCO1B3) 111552082(SLCO1B7)

CANG:

105520951(SLCO1B1) 105520962

CJC:	100404555 118144205(SLCO1B1)

SBQ:	101037794 101040380(SLCO1B3)

CIMI:

108300239 108300240 108303669 108304734

ANAN:

105705767 105713874 105713875

CSYR:

103258178 103268269

MMUR:

105882814(SLCO1B3)

LCAT:

123639947(SLCO1B3)

PCOQ:

105807606

OGA:

100966263

MMU:	28253(Slco1b2)

MCAL:

110287586

MPAH:

110314592

RNO:	58978(Slco1b2)

MCOC:

116098420(Slco1b3)

ANU:	117715178 117715436 117715443 117715788

MUN:	110564251(Slco1b3)

CGE:	100774298(Slco1b3)

MAUA:

101831757(Slco1b3)

PROB:

127213150

MORG:

121437867(Slco1b3)

MFOT:

126497213

AAMP:

119806630

NGI:

103748814

HGL:	101698204 101703116(Slco1b3)

CPOC:

100718030 100718313 100718591 100718861 100719136

CCAN:

109682212(Slco1b3)

DORD:

105992235

DSP:	122102016(Slco1b3)

PLOP:

125342875(Slco1b3)

NCAR:

124983261

MMMA:

107152711(Slco1b3)

OCU:

100342119

OPI:	101530134(SLCO1B3)

TUP:	102476084(SLCO1B3)

GVR:

103601704

CFA:	403519(SLCO1B3)

CLUD:

112665476(SLCO1B3)

VVP:	112917233(SLCO1B3)

VLG:	121479880(SLCO1B3)

NPO:	129505572(SLCO1B3)

AML:	100481529(SLCO1B3)

UMR:	103677808(SLCO1B3)

UAH:	113257823(SLCO1B3)

UAR:	123781769(SLCO1B3)

ELK:

111142168

LLV:

125107705

MPUF:

101690089(SLCO1B3)

MNP:	132019528(SLCO1B3)

MLK:	131838980(SLCO1B3)

NVS:	122891204(SLCO1B3)

ORO:	101383177(SLCO1B3)

EJU:	114200906(SLCO1B3)

ZCA:

113923148

MLX:	118025599(SLCO1B3)

NSU:	110580871(SLCO1B3)

LWW:	102732130(SLCO1B3)

FCA:

101088850

PYU:

121038851

PCOO:

112867300(SLCO1B3)

PBG:

122474016

PVIV:

125171301

LRUF:

124502303

PTG:	102970165(SLCO1B3)

PPAD:

109268690(SLCO1B3)

PUC:

125920133

AJU:

106977174

HHV:	120243012(SLCO1B3)

BTA:	404160(SLCO1B3)

BOM:	102286647(SLCO1B3)

BIU:	109559603(SLCO1B3)

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:	100620829(SLCO1B3)

CFR:

CBAI:

CDK:

VPC:

BACU:

103005519(SLCO1B3)

BMUS:

118901904

LVE:	103070192(SLCO1B3)

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:	100068155(SLCO1B3)

EPZ:	103560769(SLCO1B3)

EAI:

106825571

MYB:	102253889(SLCO1B3)

MYD:	102773004(SLCO1B3)

MMYO:

MLF:

MDT:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

RFQ:

PALE:

PGIG:

PVP:	105306541(SLCO1B3)

RAY:

107508568

MJV:

108398364

TOD:	119247650(SLCO1B3)

SARA:

101538192

SETR:

126022024(SLCO1B3)

LAV:

TMU:

ETF:

DNM:

MDO:	100011628(SLCO1B1) 100011666(SLCO1B3) 100618576(SLCO1B1)

GAS:	123249050 123249161 123249356

SHR:	100923007 100923273

AFZ:	127537971 127564111

PCW:	110213751 110213821

TVP:	118849782 118850013 118851722 118851723

OAA:

103167174

GGA:	418187(SLCO1B3)

PCOC:

TPAI:

LMUT:

CATA:

AFUL:

OTC:

PRUF:

OMA:	130254374 130254969

ZAB:

ZLE:

ACHL:

SVG:

MMEA:

HRT:

SATI:

CCRI:

NNT:

SHAB:

HALD:

104318069(SLCO1C1)

HLE:

GCL:

CSTI:

LDI:

MNB:

DPUB:

AVIT:

BRHI:

PCRI:

PCAO:

AFOR:

FGA:

GSTE:

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

CVF:

RTD:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

CPOO:

GGN:

PSS:	102458991(SLCO1B3)

CMY:	102937920(SLCO1B3)

CCAY:

125625286(SLCO1B3)

CPIC:

101952854(SLCO1B3)

TST:

117883175

CABI:

116834131(SLCO1B3)

MRV:

120384775

ACS:

100555012

ASAO:

132775733

PVT:	110088800(SLCO1B3)

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:	123034670(SLCO1B3)

PMUA:

114605418

PRAF:

128422273(SLCO1B3)

ZVI:

HCG:

GJA:

STOW:

EMC:

XTR:	613085(slco1b3)

NPR:

ARUN:

OSN:

Reference

PMID:14579113

Authors

Hagenbuch B, Meier PJ

Title

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.

Journal

Pflugers Arch 447:653-65 (2004)
DOI:10.1007/s00424-003-1168-y

Reference

PMID:12196548

Authors

Michalski C, Cui Y, Nies AT, Nuessler AK, Neuhaus P, Zanger UM, Klein K, Eichelbaum M, Keppler D, Konig J

Title

A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter.

Journal

J Biol Chem 277:43058-63 (2002)
DOI:10.1074/jbc.M207735200

Sequence

[hsa:10599]

LinkDB

DBGET integrated database retrieval system