KEGG   ORTHOLOGY: K03823
Entry
K03823                      KO                                     
Symbol
pat, bar
Name
phosphinothricin acetyltransferase [EC:2.3.1.183]
Pathway
map00440  Phosphonate and phosphinate metabolism
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K03823  pat, bar; phosphinothricin acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.183  phosphinothricin acetyltransferase
     K03823  pat, bar; phosphinothricin acetyltransferase
Other DBs
RN: R08871 R08938
COG: COG1247
GO: 0102971
Genes
VCH: VC_A0387
VCF: IR04_01735
VCE: Vch1786_II0131
VCQ: EN18_00605
VCJ: VCD_000902
VCI: O3Y_15323
VCO: VC0395_0935
VCR: VC395_A0337
VPH: VPUCM_1431
VEX: VEA_003223
VSP: VS_1280
LSS: NCTC12082_01565(yncA)
CDIZ: CEDIAZO_01076(bar_1)
RBS: RHODOSMS8_00830(bar)
SCO: SCO3203(bar)
SALB: XNR_2143
SMA: SAVERM_3695(bar)
SHY: SHJG_4675
SCT: SCAT_p1305(bar)
SFA: Sfla_3685
SALS: SLNWT_4368
SFI: SFUL_4404
SALU: DC74_3670
SALL: SAZ_19480
SLV: SLIV_21675(bar)
STRE: GZL_05219
SLD: T261_4846
SPRI: SPRI_4346
SRW: TUE45_04449(pat_2)
STRD: NI25_22705
SALJ: SMD11_5982(pat)
SFK: KY5_3412
SGE: DWG14_04848(bar)
SNF: JYK04_03797(bar)
STUI: GCM10017668_29200(bar)
SHUN: DWB77_04450(bar)
SCYG: S1361_17220(pat1)
SAUH: SU9_013940
ATL: Athai_63860(bar)
ASER: Asera_11590(bar)
RLC: K227x_21050(yncA)
AG: CAA35093(bar)
 » show all
Reference
PMID:1916276
  Authors
Bedford DJ, Lewis CG, Buttner MJ
  Title
Characterization of a gene conferring bialaphos resistance in Streptomyces coelicolor A3(2).
  Journal
Gene 104:39-45 (1991)
DOI:10.1016/0378-1119(91)90462-k
  Sequence
[sco:SCO3203]
Reference
PMID:2315036
  Authors
White J, Chang SY, Bibb MJ, Bibb MJ
  Title
A cassette containing the bar gene of Streptomyces hygroscopicus: a selectable marker for plant transformation.
  Journal
Nucleic Acids Res 18:1062 (1990)
DOI:10.1093/nar/18.4.1062
  Sequence
LinkDB

KEGG   ENZYME: 2.3.1.183
Entry
EC 2.3.1.183                Enzyme                                 
Name
phosphinothricin acetyltransferase;
PAT (ambiguous);
PPT acetyltransferase;
Pt-N-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:phosphinothricin N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + phosphinothricin = CoA + N-acetylphosphinothricin [RN:R08938]
Reaction(KEGG)
R08938;
(other) R08871
Substrate
acetyl-CoA [CPD:C00024];
phosphinothricin [CPD:C04650]
Product
CoA [CPD:C00010];
N-acetylphosphinothricin [CPD:C17952]
Comment
The substrate phosphinothricin is used as a nonselective herbicide and is a potent inhibitor of EC 6.3.1.2, glutamine synthetase, a key enzyme of nitrogen metabolism in plants [2].
History
EC 2.3.1.183 created 2007
Pathway
ec00440  Phosphonate and phosphinate metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K03823  phosphinothricin acetyltransferase
Genes
VCHVC_A0387
VCFIR04_01735
VCEVch1786_II0131
VCQEN18_00605
VCJVCD_000902
VCIO3Y_15323
VCOVC0395_0935
VCRVC395_A0337
VPHVPUCM_1431
VEXVEA_003223
VDBAL552_17220
VSPVS_1280
VCYIX92_06020
VCTJV59_32675
VEUIXK98_25610
GHOAL542_16205
SALYE8E00_06170 E8E00_07560
SKSFCN78_07210
SCOTHBA18_07525
MMAAFR932_05245
LSSNCTC12082_01565(yncA)
MMWMmwyl1_0488 Mmwyl1_0493
MARDIBG28_02175
MFOIJSY38_10985
MPRFJ8N69_09390
RFOREIFOR_00005
CDIZCEDIAZO_01076(bar_1)
PMOBHG718_07830
KMNHW532_20060
RBSRHODOSMS8_00830(bar)
SVCSTVA_27230
SCOSCO3203(bar)
SALBXNR_2143
SMASAVERM_3695(bar)
SCBSCAB_52901
SSXSACTE_2662
SHYSHJG_4675
SHOSHJGH_4437
SCTSCAT_p1305(bar)
SCYSCATT_p04190
SFASfla_3685
SALSSLNWT_4368
SFISFUL_4404
SALUDC74_3670
SALLSAZ_19480
SLVSLIV_21675(bar)
STREGZL_05219
SLDT261_4846
SLCSL103_03180
SXISXIM_43020
STRCAA958_19955
SPRISPRI_4346
SCXAS200_26305
SRWTUE45_04449(pat_2)
STRFASR50_19280
SPAVSpa2297_13945
SGSAVL59_43885
STSIA4E84_16850
SKYD0C37_12550
SALWCP975_14770
SGMGCM10017557_33280(bar)
SCADDN051_22560
SNRSNOUR_24255
STRDNI25_22705
SNWBBN63_20220
SSIAA7J05_20630
SPUNBFF78_24325
SGVB1H19_17760
SALJSMD11_5982(pat)
STROSTRMOE7_01175 STRMOE7_16770 STRMOE7_36645
SFKKY5_3412
SGEDWG14_04848(bar)
SRJSRO_4275 SRO_7411
SDXC4B68_23120
SQZFQU76_12825
SCYAEJ357_19345
SASTCD934_19325
SKACP970_01750 CP970_25190
SNKCP967_20085
SHAWCEB94_17470
SRKFGW37_32600
SGALCP966_15470
SFYGFH48_23420
SGFHEP81_04444 HEP81_07732
SSEOD0Z67_12115
SBYH7H31_06280
SRIMCP984_23780
SPHVF9278_19685
SFUGCNQ36_14670
SPACB1H29_21450
STSUB7R87_12385
SCHACP983_25065
SCOECP976_18770
SBATG4Z16_18880
SSPBCP982_18845
SNFJYK04_03797(bar)
SPLACP981_16475
STUIGCM10017668_29200(bar)
SATAC5746_17635
SCHFIPT68_15795
SHUNDWB77_04450(bar)
SHARHUT13_21440
SCYGS1361_17220(pat1)
SFEUIM697_04880
SDWK7C20_15770
SAUHSU9_013940
SMOBJ7W19_03745
SPEUCGZ69_14775
SROIIAG44_23770
SXNIAG42_20305
SHKJ2N69_14995
SANUK7396_21090
SDDD9753_20470
SACTDMT42_16955
NOQLN652_00785
STPStrop_0082
ATLAthai_63860(bar)
ASERAsera_11590(bar)
GLYK3N28_14315
RLCK227x_21050(yncA)
 » show all
Reference
1  [PMID:1864506]
  Authors
Botterman J, Gossele V, Thoen C, Lauwereys M.
  Title
Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins.
  Journal
Gene 102:33-7 (1991)
DOI:10.1016/0378-1119(91)90534-I
Reference
2  [PMID:12232195]
  Authors
Droge-Laser W, Siemeling U, Puhler A, Broer I.
  Title
The Metabolites of the Herbicide L-Phosphinothricin (Glufosinate) (Identification, Stability, and Mobility in Transgenic, Herbicide-Resistant, and Untransformed Plants).
  Journal
Plant Physiol 105:159-166 (1994)
DOI:10.1104/pp.105.1.159
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.183
IUBMB Enzyme Nomenclature: 2.3.1.183
ExPASy - ENZYME nomenclature database: 2.3.1.183
BRENDA, the Enzyme Database: 2.3.1.183
LinkDB

KEGG   REACTION: R08871
Entry
R08871                      Reaction                               
Name
acetyl-CoA:demethylphosphinothricin N-acetyltransferase
Definition
Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA
Equation
Comment
phosphinothricin acetyltransferase
Reaction class
RC00004  C00010_C00024
RC00064  C17949_C17962
Enzyme
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K03823  phosphinothricin acetyltransferase [EC:2.3.1.183]
LinkDB

DBGET integrated database retrieval system