KEGG   ORTHOLOGY: K03823
Entry
K03823                      KO                                     
Symbol
pat, bar
Name
phosphinothricin acetyltransferase [EC:2.3.1.183]
Pathway
map00440  Phosphonate and phosphinate metabolism
map01110  Biosynthesis of secondary metabolites
Reaction
R08871  acetyl-CoA:demethylphosphinothricin N-acetyltransferase
R08938  acetyl-CoA:phosphinothricin N-acetyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K03823  pat, bar; phosphinothricin acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.183  phosphinothricin acetyltransferase
     K03823  pat, bar; phosphinothricin acetyltransferase
Other DBs
COG: COG1247
GO: 0102971
Genes
PROD: PCO85_07970
VCH: VC_A0387
VCF: IR04_01735
VCE: Vch1786_II0131
VCQ: EN18_00605
VCJ: VCD_000902
VCI: O3Y_15323
VCO: VC0395_0935
VCR: VC395_A0337
VPH: VPUCM_1431
VEX: VEA_003223
VDB: AL552_17220
VSP: VS_1280
VCY: IX92_06020
VCT: JV59_32675
VEU: IXK98_25610
VGI: MID13_08975
VSL: LTQ54_15840
VCRA: IS519_00950
VNP: KW548_11420
GHO: AL542_16205
GKD: K6Q96_09885
SALY: E8E00_06170 E8E00_07560
SKS: FCN78_07210
SCOT: HBA18_07525
SPRO: N7E60_06295 N7E60_07670
MMAA: FR932_05245
LSS: NCTC12082_01565(yncA)
MMW: Mmwyl1_0488 Mmwyl1_0493
MARD: IBG28_02175
MFOI: JSY38_10985
MPRF: J8N69_09390
MRHI: KDW99_02270
RFO: REIFOR_00005
CDIZ: CEDIAZO_01076(bar_1)
PMOB: HG718_07830
KMN: HW532_20060
RBS: RHODOSMS8_00830(bar)
SVC: STVA_27230
HFL: PUV54_00930
BBOR: RFB14_09405
MPAA: MKK62_18715
MMEH: M5I08_09000
SCO: SCO3203(bar)
SALB: XNR_2143
SMA: SAVERM_3695(bar)
SFI: SFUL_4404
SGRF: SGFS_052100
SCB: SCAB_52901
SSX: SACTE_2662
SHY: SHJG_4675
SHO: SHJGH_4437
SFA: Sfla_3685
SALS: SLNWT_4368
SLV: SLIV_21675(bar)
STRE: GZL_05219
SLD: T261_4846
SLC: SL103_03180
SXI: SXIM_43020
STRC: AA958_19955
SPRI: SPRI_4346
SCX: AS200_26305
SRW: TUE45_04449(pat_2)
STRF: ASR50_19280
SPAV: Spa2297_13945
SGS: AVL59_43885
STSI: A4E84_16850
SKY: D0C37_12550
SALW: CP975_14770
SGM: GCM10017557_33280(bar)
SCAD: DN051_22560
SPHW: NFX46_37010
SNR: SNOUR_24255
SALU: DC74_3670
SALL: SAZ_19480
STRD: NI25_22705
SNW: BBN63_20220
SSIA: A7J05_20630
SPUN: BFF78_24325
SGV: B1H19_17760
SALJ: SMD11_5982(pat)
STRO: STRMOE7_01175 STRMOE7_16770 STRMOE7_36645
SFK: KY5_3412
SGE: DWG14_04848(bar)
SRJ: SRO_4275 SRO_7411
SDX: C4B68_23120
SQZ: FQU76_12825
SCYA: EJ357_19345
SAST: CD934_19325
SKA: CP970_01750 CP970_25190
SNK: CP967_20085
SHAW: CEB94_17470
SRK: FGW37_32600
SGAL: CP966_15470
SFY: GFH48_23420
SGF: HEP81_04444 HEP81_07732
SSEO: D0Z67_12115
SBY: H7H31_06280
SRIM: CP984_23780
SPHV: F9278_19685
SFUG: CNQ36_14670
SPAC: B1H29_21450
STSU: B7R87_12385
SCHA: CP983_25065
SCOE: CP976_18770
SBAT: G4Z16_18880
SSPB: CP982_18845
SNF: JYK04_03797(bar)
SPLA: CP981_16475
STUI: GCM10017668_29200(bar)
SATA: C5746_17635
SCHF: IPT68_15795
SHUN: DWB77_04450(bar)
SHAR: HUT13_21440
SCYG: S1361_17220(pat1)
SFEU: IM697_04880
SDW: K7C20_15770
SAUH: SU9_013940
SMOB: J7W19_03745
SPEU: CGZ69_14775
SROI: IAG44_23770
SXN: IAG42_20305
SHK: J2N69_14995
SANU: K7396_21090
SDD: D9753_20470
SACT: DMT42_16955
SGOB: test1122_09365
SINE: KI385_19550
SLF: JEQ17_19885
SDEC: L3078_19450
SDUR: M4V62_24475
SAKB: K1J60_25540
SNIG: HEK616_00970(bar)
SVIO: HWN34_11415
SCAE: IHE65_26130
SSPN: LXH13_23660
SLON: LGI35_20500
STUD: STRTU_004150
SENG: OJ254_12030
SYUN: MOV08_24400
SARG: HKX69_19760
SJN: RI060_24680
SCYN: N8I84_17705
SCT: SCAT_p1305(bar)
SCY: SCATT_p04190
ABRY: NYE86_04320
AMAZ: LUW76_15330
KBU: Q4V64_21590 Q4V64_53470
STP: Strop_0082
ACTL: L3i22_057200(bar)
ATL: Athai_63860(bar)
ASER: Asera_11590(bar)
GLY: K3N28_14315
RLC: K227x_21050(yncA)
AG: CAA35093(bar)
 » show all
Reference
PMID:1916276
  Authors
Bedford DJ, Lewis CG, Buttner MJ
  Title
Characterization of a gene conferring bialaphos resistance in Streptomyces coelicolor A3(2).
  Journal
Gene 104:39-45 (1991)
DOI:10.1016/0378-1119(91)90462-k
  Sequence
[sco:SCO3203]
Reference
PMID:2315036
  Authors
White J, Chang SY, Bibb MJ, Bibb MJ
  Title
A cassette containing the bar gene of Streptomyces hygroscopicus: a selectable marker for plant transformation.
  Journal
Nucleic Acids Res 18:1062 (1990)
DOI:10.1093/nar/18.4.1062
  Sequence
[ag:CAA35093]
LinkDB

KEGG   ENZYME: 2.3.1.183
Entry
EC 2.3.1.183                Enzyme                                 
Name
phosphinothricin acetyltransferase;
PAT (ambiguous);
PPT acetyltransferase;
Pt-N-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:phosphinothricin N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + phosphinothricin = CoA + N-acetylphosphinothricin [RN:R08938]
Reaction(KEGG)
R08938;
(other) R08871
Substrate
acetyl-CoA [CPD:C00024];
phosphinothricin [CPD:C04650]
Product
CoA [CPD:C00010];
N-acetylphosphinothricin [CPD:C17952]
Comment
The substrate phosphinothricin is used as a nonselective herbicide and is a potent inhibitor of EC 6.3.1.2, glutamine synthetase, a key enzyme of nitrogen metabolism in plants [2].
History
EC 2.3.1.183 created 2007
Pathway
ec00440  Phosphonate and phosphinate metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K03823  phosphinothricin acetyltransferase
Genes
PROD: PCO85_07970
VCH: VC_A0387
VCF: IR04_01735
VCE: Vch1786_II0131
VCQ: EN18_00605
VCJ: VCD_000902
VCI: O3Y_15323
VCO: VC0395_0935
VCR: VC395_A0337
VPH: VPUCM_1431
VEX: VEA_003223
VDB: AL552_17220
VSP: VS_1280
VCY: IX92_06020
VCT: JV59_32675
VEU: IXK98_25610
VGI: MID13_08975
VSL: LTQ54_15840
VCRA: IS519_00950
VNP: KW548_11420
GHO: AL542_16205
GKD: K6Q96_09885
SALY: E8E00_06170 E8E00_07560
SKS: FCN78_07210
SCOT: HBA18_07525
SPRO: N7E60_06295 N7E60_07670
MMAA: FR932_05245
LSS: NCTC12082_01565(yncA)
MMW: Mmwyl1_0488 Mmwyl1_0493
MARD: IBG28_02175
MFOI: JSY38_10985
MPRF: J8N69_09390
MRHI: KDW99_02270
RFO: REIFOR_00005
CDIZ: CEDIAZO_01076(bar_1)
PMOB: HG718_07830
KMN: HW532_20060
RBS: RHODOSMS8_00830(bar)
SVC: STVA_27230
HFL: PUV54_00930
BBOR: RFB14_09405
MPAA: MKK62_18715
MMEH: M5I08_09000
SCO: SCO3203(bar)
SALB: XNR_2143
SMA: SAVERM_3695(bar)
SFI: SFUL_4404
SGRF: SGFS_052100
SCB: SCAB_52901
SSX: SACTE_2662
SHY: SHJG_4675
SHO: SHJGH_4437
SFA: Sfla_3685
SALS: SLNWT_4368
SLV: SLIV_21675(bar)
STRE: GZL_05219
SLD: T261_4846
SLC: SL103_03180
SXI: SXIM_43020
STRC: AA958_19955
SPRI: SPRI_4346
SCX: AS200_26305
SRW: TUE45_04449(pat_2)
STRF: ASR50_19280
SPAV: Spa2297_13945
SGS: AVL59_43885
STSI: A4E84_16850
SKY: D0C37_12550
SALW: CP975_14770
SGM: GCM10017557_33280(bar)
SCAD: DN051_22560
SPHW: NFX46_37010
SNR: SNOUR_24255
SALU: DC74_3670
SALL: SAZ_19480
STRD: NI25_22705
SNW: BBN63_20220
SSIA: A7J05_20630
SPUN: BFF78_24325
SGV: B1H19_17760
SALJ: SMD11_5982(pat)
STRO: STRMOE7_01175 STRMOE7_16770 STRMOE7_36645
SFK: KY5_3412
SGE: DWG14_04848(bar)
SRJ: SRO_4275 SRO_7411
SDX: C4B68_23120
SQZ: FQU76_12825
SCYA: EJ357_19345
SAST: CD934_19325
SKA: CP970_01750 CP970_25190
SNK: CP967_20085
SHAW: CEB94_17470
SRK: FGW37_32600
SGAL: CP966_15470
SFY: GFH48_23420
SGF: HEP81_04444 HEP81_07732
SSEO: D0Z67_12115
SBY: H7H31_06280
SRIM: CP984_23780
SPHV: F9278_19685
SFUG: CNQ36_14670
SPAC: B1H29_21450
STSU: B7R87_12385
SCHA: CP983_25065
SCOE: CP976_18770
SBAT: G4Z16_18880
SSPB: CP982_18845
SNF: JYK04_03797(bar)
SPLA: CP981_16475
STUI: GCM10017668_29200(bar)
SATA: C5746_17635
SCHF: IPT68_15795
SHUN: DWB77_04450(bar)
SHAR: HUT13_21440
SCYG: S1361_17220(pat1)
SFEU: IM697_04880
SDW: K7C20_15770
SAUH: SU9_013940
SMOB: J7W19_03745
SPEU: CGZ69_14775
SROI: IAG44_23770
SXN: IAG42_20305
SHK: J2N69_14995
SANU: K7396_21090
SDD: D9753_20470
SACT: DMT42_16955
SGOB: test1122_09365
SINE: KI385_19550
SLF: JEQ17_19885
SDEC: L3078_19450
SDUR: M4V62_24475
SAKB: K1J60_25540
SNIG: HEK616_00970(bar)
SVIO: HWN34_11415
SCAE: IHE65_26130
SSPN: LXH13_23660
SLON: LGI35_20500
STUD: STRTU_004150
SENG: OJ254_12030
SYUN: MOV08_24400
SARG: HKX69_19760
SJN: RI060_24680
SCYN: N8I84_17705
SCT: SCAT_p1305(bar)
SCY: SCATT_p04190
ABRY: NYE86_04320
AMAZ: LUW76_15330
KBU: Q4V64_21590 Q4V64_53470
STP: Strop_0082
ACTL: L3i22_057200(bar)
ATL: Athai_63860(bar)
ASER: Asera_11590(bar)
GLY: K3N28_14315
RLC: K227x_21050(yncA)
 » show all
Reference
1  [PMID:1864506]
  Authors
Botterman J, Gossele V, Thoen C, Lauwereys M.
  Title
Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins.
  Journal
Gene 102:33-7 (1991)
DOI:10.1016/0378-1119(91)90534-I
Reference
2  [PMID:12232195]
  Authors
Droge-Laser W, Siemeling U, Puhler A, Broer I.
  Title
The Metabolites of the Herbicide L-Phosphinothricin (Glufosinate) (Identification, Stability, and Mobility in Transgenic, Herbicide-Resistant, and Untransformed Plants).
  Journal
Plant Physiol 105:159-166 (1994)
DOI:10.1104/pp.105.1.159
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.183
IUBMB Enzyme Nomenclature: 2.3.1.183
ExPASy - ENZYME nomenclature database: 2.3.1.183
BRENDA, the Enzyme Database: 2.3.1.183
LinkDB

KEGG   REACTION: R08871
Entry
R08871                      Reaction                               
Name
acetyl-CoA:demethylphosphinothricin N-acetyltransferase
Definition
Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA
Equation
C17962 + C00024 <=> C17949 + C00010
Comment
phosphinothricin acetyltransferase
Reaction class
RC00004  C00010_C00024
RC00064  C17949_C17962
Enzyme
2.3.1.183
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.183
     R08871  Demethylphosphinothricin + Acetyl-CoA <=> N-Acetyldemethylphosphinothricin + CoA
Orthology
K03823  phosphinothricin acetyltransferase [EC:2.3.1.183]
LinkDB

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