KEGG ORTHOLOGY: K03878

TC:

Genes

HSA:

4535(ND1)

PTR:	807867(ND1)

PPS:	807884(ND1)

GGO:	6742683(ND1)

PON:	808473(ND1)

PPYG:

807903(ND1)

NLE:	16545241(ND1)

SSYN:

9072789(ND1)

MCC:	2846627(ND1)

MCF:	7857751(ND1)

CSAB:

4097488(ND1)

CATY:

26408639(ND1)

PANU:

14444642(ND1)

TGE:	14216794(ND1)

RRO:	4171534(ND1)

RBB:	10549380(ND1)

TFN:	18985085(ND1)

CJC:	22203913(ND1)

SBQ:	13228911(ND1)

ANAN:

13230279(ND1)

CSYR:

7944474(ND1)

MMUR:

26823996(ND1)

LCAT:

68929174(ND1)

PCOQ:

6458118(ND1)

MMU:	17716(ND1)

MCAL:

20832255(ND1)

MPAH:

36165356(ND1)

RNO:	26193(ND1)

MCOC:

34682989(ND1)

MUN:	18129817(ND1)

CGE:	3979183(ND1)

MAUA:

8457936(ND1)

PROB:

30213863(BOP69_gp13)

PLEU:

36275544(ND1)

PMAV:

39105338(ND1)

NGI:	15088436(ND1)

HGL:	10201222(ND1)

CPOC:

808631(ND1)

CCAN:

31082893(ND1)

ITI:	24576609(ND1)

OCU:	808226(ND1)

OPI:	2717280(ND1)

GVR:	804978(ND1)

CFA:	804476(ND1)

VVP:	4355757(ND1)

VLG:	23629759(ND1)

NPO:	8690253(ND1)

AML:	5179729(ND1)

UMR:	804861(ND1)

UAR:	804833(ND1)

LLV:	71922402(ND1)

MNP:	20466151(ND1)

NVS:	14841852(ND1)

EJU:	805015(ND1)

ZCA:	4355794(ND1)

MLX:	4355870(ND1)

LWW:	4355832(ND1)

FCA:	807939(ND1)

PYU:	26129864(ND1)

PCOO:

11473378(ND1)

PBG:	26129484(ND1)

PVIV:

26129636(ND1)

LGF:	26130206(ND1)

AJU:	2654018(ND1)

PPAD:

6262379(ND1)

PUC:	6262408(ND1)

PLEZ:

26129522(ND1)

HHV:	14842168(ND1)

BTA:	3283877(ND1)

BOM:	22161779(ND1)

BIU:	2885975(ND1)

BJV:	7901820(ND1)

BBUB:

56055846(ND1)

CHX:	1485856(ND1)

OAS:	808249(ND1)

OCAN:

11029996(ND1)

BTAX:

8250974(ND1)

CSUM:

14841698(ND1)

ODA:	11452038(ND1)

CCAD:

59433129(ND1)

MREE:

805171(ND1)

OVR:	10322925(ND1)

MBEZ:

7872555(ND1)

SSC:	808501(ND1)

CFR:	5326219(ND1)

CBAI:

5309946(ND1)

CDK:	5618953(ND1)

VPC:	809425(ND1)

BMUS:

807743(ND1)

LVE:	3802087(ND1)

OOR:	72909410(ND1)

LALB:

2658618(ND1)

DLE:	31412977(ND1)

PCAD:

809418(ND1)

ECB:	807846(ND1)

EPZ:	19019447(ND1)

EAI:	808061(ND1)

MYB:	20964692(ND1)

MYD:	22203923(ND1)

MMYO:

26889517(ND1)

MLF:	27214809(ND1)

DRO:	17046640(ND1)

AJM:	808336(ND1)

PDIC:

74550843(ND1)

HAI:	13539878(ND1)

PALE:

17963481(ND1)

MJV:	24019682(ND1)

TOD:	38289010(D9W85_mgp13)

LAV:	808794(ND1)

ETF:	802330(ND1)

DNM:	808126(ND1)

MDO:	3074661(ND1)

GAS:	63652827(ND1)

SHR:	13826446(ND1)

AFZ:	65342071(ND1)

PCW:	4108302(ND1)

TVP:	803525(ND1)

OAA:	808708(ND1)

GGA:	39116926(ND1)

PCOC:

10609909(ND1)

MGP:	5848011(ND1)

CJO:	804668(ND1)

LMUT:

31079457(ND1)

NMEL:

32282781(ND1)

APLA:

5405817(ND1)

ACYG:

18887311(ND1)

CATA:

7996697(ND1)

AFUL:

19909408(ND1)

TGU:	3950790(ND1)

LSR:	26897959(ND1)

VMC:	63024168(ND1)

SCAN:

37275780(ND1)

PMOA:

20355709(ND1)

OTC:	22548471(ND1)

PRUF:

17674390(ND1)

MATE:

60253626(ND1)

MAEN:

13825799(ND1)

FAB:	16027862(ND1)

PHI:	9481005(ND1)

PMAJ:

39089575(ND1)

CCW:	71712370(ND1)

ACOE:

60235406(ND1)

MMEA:

130587653 20357145(ND1)

SATI:

5846211(ND1)

FPG:	808589(ND1)

FCH:	23808611(ND1)

FRS:	26890162(ND1)

AGEN:

7256443(ND1)

EGZ:	18985247(ND1)

NNI:	4108698(ND1)

PADL:

26737698(ND1)

GSTE:

3416060(ND1)

CBOY:

809232(ND1)

CLV:	8890008(ND1)

GAME:

14840904(ND1)

RTD:	84348643(ND1)

AROW:

62676585(ND1)

NPD:	62676474(ND1)

DNE:	803255(ND1)

ASN:	806142(ND1)

AMJ:	808237(ND1)

CPOO:

4108090(ND1)

GGN:	4178388(ND1)

PSS:	2943117(ND1)

CIZ:	25099114(ND1)

CMY:	808642(ND1)

CCAY:

11747776(ND1)

CPIC:

18983007(ND1)

CABI:

60253682(ND1)

ACS:	6385981(ND1)

PVT:	3338357(ND1)

PBI:	YP_008083599

PMUR:

15822643(ND1)

PMUA:

7056473(ND1)

ZVI:	24146092(YC27_gp13)

GJA:	26044419(ND1)

EMC:	30861809(ND1)

XLA:	2642086(ND1)

XTR:	3283492(ND1)

NPR:	24020224(ND1)

ACAT:

17427726(ND1)

PADS:

41662617(ND1)

BGAR:

4356060(ND1)

MUO:	18490108(ND1)

GSH:	14469882(ND1)

DRE:	140531(ND1)

SRX:	24419169(ND1)

SANH:

24419957(ND1)

SGH:	8382175(ND1)

CCAR:

807764(ND1)

CGIB:

9222077(ND1)

PTET:

5787383(ND1)

LROH:

12079590(ND1)

OMC:	18668130(ND1)

PPRM:

26048334(ND1)

MAMB:

5912302(ND1)

CIDE:

5857715(ND1)

CERY:

20160558(ND1)

MASI:

3131142(ND1)

TROS:

14048448(ND1)

TDW:	36952182(ND1)

MANU:

6879722(ND1)

PDAB:

18668409(ND1)

IPU:	804880(ND1)

IFU:	26118477(ND1)

PHYP:

16216580(ND1)

SMEO:

10079910(ND1)

TVC:	10079799(ND1) 132858793

CGAR:

128512071 25103328(ND1)

TRN:	134307549 134307555 134307586 134307597

CHAR:

5228442(ND1)

ASAD:

9978345(ND1)

TRU:	805222(ND1)

TFS:	19524531(ND1)

TNG:	BAE79217(ND1)

LCO:	7095394(ND1)

NCC:	10752035(ND1)

PGEO:

67284283(ND1)

EMAC:

30862027(ND1)

ELY:	7095516(ND1)

EFO:	14412340(ND1)

PLEP:

4363295(ND1)

SLUC:

23629815(ND1)

SVIT:

26128876(ND1)

ESP:	40141426(ND1)

PFLV:

14048206(ND1)

AFB:	13230441(ND1)

PSWI:

72130153(ND1)

AMIR:

36838985(ND1)

MSAM:

4100035(ND1)

SCHU:

10965121(ND1)

EARM:

8382053(ND1)

CUD:	8774884(ND1)

LMIX:

132960641

MZE:

26037634

ONL:	8677324(ND1)

OAU:	8745952(ND1)

OLA:	805441(ND1)

OML:	13540120(ND1)

CSAI:

804095(ND1)

XMA:	6986203(ND1)

XCO:	26048182(ND1)

XHE:	8302520(ND1)

PRET:

19590702(ND1)

GAF:	805456(ND1)

CVG:	26048372(ND1)

CTUL:

26129142(ND1)

NFU:	7256390(ND1)

KMR:	804473(ND1)

AOCE:

4850676(ND1)

CSEM:

7996493(ND1)

POV:	808850(ND1)

SSEN:

4266845(ND1)

HHIP:

5405703(ND1)

HSP:	5405777(ND1)

SMAU:

8382072(ND1)

LCF:	3703587(ND1)

SDU:	11669686(ND1)

XGL:	7871594(ND1)

HCQ:	14658023(ND1)

SBIA:

35996578(ND1)

PTAO:

74193740(ND1)

BPEC:

YP_004935131.1

MALB:

803935(ND1)

BSPL:

23631943(ND1)

SJO:	8703813(ND1)

GMH:	808449(ND1)

SASA:

808311(ND1)

STRU:

19099188(ND1)

OTW:	KEF73_p13(ND1)

OMY:	807982(ND1)

OGO:	6383214(ND1)

ONE:	4555718(ND1)

OKI:	4955078(ND1)

OKE:	12486859(ND1)

OMM:	4657587(ND1)

SALP:

808544(ND1)

SNH:	35115211(ND1)

CCLU:

14842644(ND1)

ELS:	806647(ND1)

SFM:	3416104(ND1)

AANG:

3190265(ND1)

LOC:	807198(ND1)

PSPA:

805407(ND1)

ARUT:

17097831(ND1)

LCM:	808083(ND1)

CMK:	9385357(ND1)

RTP:	18267189(ND1)

CPLA:

7768754(ND1)

SCAU:

808294(ND1)

LERI:

11452178(ND1)

HAKA:

15333378(ND1)

PMRN:

807812(ND1)

LRJ:	9385087(ND1)

BFO:	808737(ND1)

BBEL:

806242(ND1)

SCLV:

36165640(ND1)

SPU:	2652716(ND1)

LVG:	36941436(ND1)

AJJ:	139965208 139965209 7802878(ND1)

APLC:

3907679(ND1)

AAMU:

3239014(ND1)

SKO:	3703613(ND1)

DME:	Dmel_CG34092(ND1)

DER:

113564595

DSE:	2760947(ND1)

DSI:

DYA:

DAN:	116655729 26515294

DGR:

116806146

CCAT:

808526(ND1)

BOD:	138856454 2717263(ND1)

BDR:	4657581(ND1)

AOQ:	79023100(ND1)

TDA:

119665298

MDE:	20358598(ND1)

SCAC:

131996656

LSQ:	5469270(ND1)

ECOE:

35199162(ND1)

HIS:	33350942(ND1)

AGA:	85940932(ND1)

ACOZ:

26121334(ND1)

AARA:

26121220(ND1)

AMER:

26121524(ND1)

AMAP:

73620792(ND1)

AFUN:

76054184(ND1)

AMOU:

73620868(ND1)

AMRS:

73620830(ND1)

ANIL:

73620944(ND1)

ADAR:

73621020(ND1)

AAG:	33307571(ND1)

AALB:

3260128(ND1)

CQU:

CPII:

10200339(ND1)

CBRI:

87696349(ND1)

BCOO:

119082522

PPAP:

129809031 129809035 26044662(ND1)

ACER:

9385649(ND1)

ALAB:

34829171(ND1)

AFLR:

15822494(ND1)

BAFF:

126928013 126928669

SOC:	9977800(ND1)

VEM:	27912165(ND1)

CFO:

109610427

LHU:	136998169 42265456(ND1)

PGC:

109862627

TPRE:

111693311

LBD:

127290340

AGIF:

63649842(ND1)

CCIN:

107274032 7872303(ND1)

AROA:

112694907

TCA:	803824(ND1)

TMOL:

138140755

SOY:	28481415(ND1)

ATD:	34926375(ND1)

AGB:	4171595(ND1)

APLN:

28479658(ND1)

OTU:

111425784

BMOR:

809263(ND1)

BMAN:

804653(ND1)

MSEX:

5848758(ND1)

DPL:	AGL76310(ND1)

BANY:

128199783

PMAC:

106711773 13080339(ND1)

PPOT:

106103434 106106472 106110406 20159557(ND1)

PXU:	106116406 26836895(ND1)

PRAP:

11030472(ND1)

PNAP:

60241357(ND1)

LSIN:

126969268

HAW:	9977723(ND1)

HZE:	124645586 124645589 71203150(ND1)

TNL:	44149132(ND1)

SLIU:

17427405(ND1)

GMW:	26376102(ND1)

ECLR:

140757094

PXY:	20834457(ND1)

PGW:	73956692(ND1)

CSTB:

134752859

CFUM:

36490495(ND1)

API:	7055886(ND1)

DNX:	17428420(ND1)

AGS:	19909111(ND1)

BTAB:

109035889 109040671 3077225(ND1)

DCI:	113467916 27914382(ND1)

CLEC:

27787568(ND1)

HHAL:

106685853 8457893(ND1)

NLU:	16216537(ND1)

LDA:	7996610(ND1)

HVI:	3332274(ND1)

MQU:	32891633(ND1)

FOC:	YP_006576363

TPAL:

38092123(ND1)

ZNE:	20004821(ND1)

SGRE:

73491817(ND1)

DPX:	AAD33242(ND1)

DMK:	24147219(ND1)

DPZ:

124311800

AFRA:

136040621 807793(ND1)

PVM:	113820287 138863283 5333210(ND1)

PJA:	3416046(ND1)

PCHN:

5333406(ND1)

PMOO:

808981(ND1)

HAME:

10743682(ND1) 121861319 121871283

PCLA:

11763616(ND1)

CQD:	128705058 17728541(ND1)

PTRU:

1482828(ND1)

SPRM:

7768780(ND1)

ESN:	126986713 3355539(ND1)

MNZ:	10200254(ND1) 135223734

MRJ:	136841169 136847488 136851865 3293137(ND1)

PORN:

10094407(ND1)

HAZT:

38169087(ND1)

OOT:	9481017(ND1)

TCF:	4788311(ND1)

DSV:	23630423(ND1)

RSAN:

808372(ND1)

RMP:	18250941(ND1)

VDE:	806163(ND1)

TUT:	6164207(ND1)

DPTE:

7564650(ND1)

CVS:

136988988

LPOL:

106462800 803780(ND1)

CEL:	KEF34_p10(ND1)

CBR:

NAI:	804826(ND1)

BMY:	KEF88_p05(ND1)

LOA:

TSP:

HRO:	HELRODRAFT_92831

PCAN:

19909181(ND1)

LSAX:

28261522(ND1)

BARL:

143298976 17960489(ND1)

BGT:	2746312(ND1)

HRF:	35985161(ND1)

HRJ:	2846696(ND1)

CRG:	808836(ND1)

CANU:

7865916(ND1)

MYI:	4910437(ND1)

PMAX:

117319647 117319648

YBA:

132550986

MMER:

55289766(ND1)

RPHI:

29141325(ND1)

MAEA:

20159500(ND1)

OBI:	27205972(ND1)

OSN:	62676641(ND1)

LJP:	135481441 135481442 79134705(ND1)

LAK:	C2G87_mgp06(ND1)

SMM:

SHX:	4097440(ND1)

EGL:	41697853(nad1)

ATEN:

41854778(ND1)

ADF:	17674599(ND1)

PDAM:

5580403(ND1)

SPIS:

6798792(ND1)

DGT:	8656266(ND1)

HMG:	6904241(ND1)

HSY:	130628201 130628250

RES:	33911769(ND1)

TAD:	TradoM_p19(ND1)

AQU:	4794361(ND1)

ATH:	DA397_mgp34(nad1)

CRB:	40490704(nad1)

BRP:	56141010(nad1)

BNA:	4237888(nad1)

RSZ:	13630174(nad1)

THJ:

104820711

CPAP:

7441422(nad1)

CIT:	36487065(nad1)

GRA:	27429634(nad1)

GAB:	33134351(nad1)

EGR:	38466560(nad1)

GMX:	15308632(nad1)

PVU:	42317462(nad1)

VUN:	114171284 114171347 114172406

CCAJ:

109793693

APRC:

113851155

MTR:	26974318(nad1)

TPRA:

55290723(nad1)

CAM:

101490819

PSAT:

127133940

AIP:

107647095

AHF:	112754623 114926186 114927343

MDM:	13630238(nad1)

MSYL:

73938927(nad1)

ZJU:	27215287(nad1)

CSAV:

27215501(nad1)

CSV:	11123890(nad1)

BHJ:	120079171 120087066

RCU:	10221448(nad1)

MEAN:

126667523

MESC:

42317495(nad1)

QSU:

112003814

VVI:	7498511(nad1)

SPEN:

34925974(nad1) 34926038(nad1)

CANN:

19989177(nad1)

NTA:	3205188(nad1)

NSY:	27214892(nad1)

NAU:	109207198 109239076 109244851 35198935(nad1)

INI:	29082032(nad1)

SMIL:

18126425(nad1)

LSV:	40498716(nad1)

DCR:	88614217(nad1)

AGRV:

68216281(nad1)

CSIN:

40867580(nad1)

RVL:

131300219

AEW:	88577547(nad1)

BVG:	809450(nad1)

SLAF:

9725758(nad1)

NNU:	28482718(nad1)

MING:

122071019 122089809

TSS:

122640180

PSOM:

113294875

OSA:	6450162(nad1)

DOSA:

nad1

TDC:	119270059 119272928 119279052 119279551 119280945 119283422 119284113 119308987 119310187 119315692 119325602 119333638 119354776

TAES:

123081765 123149586 34688809(nad1)

TUA:

125546263

HVG:	123424872 123426253

SBI:	4306037(nad1)

PVIR:

120693847 120694100

PHAI:

112893409

PDA:	11542581(nad1)

DCT:

114578845

PEQ:

110019532

NCOL:

36487343(nad1)

CJF:	131043336 131057905

PPP:	3989054(nad1)

CRE:	ChrepMp07(nad1)

CSL:	CospCoM_p05(nad1)

CVR:	OJ20_p09(nad1)

APRO:

ChprMp009(nad1)

OTA:	OstapMp29(nad1)

BPG:	BathyMg00020(nad1)

MIS:	MicpuN_mit12(nad1_1) MicpuN_mit40(nad1_2)

GSL:	JL72_p12(nad1)

CCP:	ChcroMp14(nad1)

DHA:

LBG:	89432272(nad1)

CAL:	CaalfMp03(NAD1)

CLUS:

16792601(nad1)

YLI:	802607(nd1)

NCR:

NCU16018

PAN:	PoanfMp49(nad1)

CTHR:

CTHT_m000470

SSCK:

SPSK_11053

FGR:	GizefMp11(nad1)

PTKZ:

MRV25_mgp07(nad1)

VAL:	VDBG_17004 VDBG_17017

CLUP:

AYB75_mgp14(nad1)

SSL:	SS1G_20036

ANI:	ANID_20007

ANG:	Asnifp02(nad1)

ALUC:

EJ508_mgp16(nad1)

PNO:	SNOGp08(nad1)

TML:	GSTUM_00002043001

CNG:	CNAG_09000

KSH:	87952611(IL334_000480) 87952639(IL334_000508)

ABP:	AGABI1DRAFT47778(AGABI1DRAFT_47778)

MRT:	D9L16_mgp10(nad1)

PSTR:

EFH26_mgp13(nad1)

DDI:	DidioMp14(nad1)

DFA:	Difao_mp13(nad1)

TET:	TepyoMp40(nad1_a)

PSOJ:

PhsooMp30(nad1)

Reference

PMID:6260957

Authors

Sanger F, Coulson AR, Barrell BG, Smith AJ, Roe BA

Title

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.

Journal

J Mol Biol 143:161-78 (1980)
DOI:10.1016/0022-2836(80)90196-5

Sequence

[hsa:4535]

LinkDB

ORTHOLOGY: K03879

Entry

K03879                      KO

Symbol

ND2

Name

NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00068

Leber hereditary optic atrophy

H00473

Mitochondrial complex I deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
  09159 Environmental adaptation
   04714 Thermogenesis
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
   05012 Parkinson disease
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
   05014 Amyotrophic lateral sclerosis
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
   05016 Huntington disease
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
   05020 Prion disease
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
   05022 Pathways of neurodegeneration - multiple diseases
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03879  ND2; NADH-ubiquinone oxidoreductase chain 2
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03879  ND2; NADH-ubiquinone oxidoreductase chain 2

Other DBs

GO:

TC:

Genes

HSA:

4536(ND2)

PTR:	807865(ND2)

PPS:	807883(ND2)

GGO:	6742677(ND2)

PON:	808478(ND2)

PPYG:

807907(ND2)

NLE:	16545240(ND2)

SSYN:

9072795(ND2)

MCC:	2846626(ND2)

MCF:	7857750(ND2)

CSAB:

4097489(ND2)

CATY:

26408637(ND2)

PANU:

14444630(ND2)

TGE:	14216782(ND2)

RRO:	4171535(ND2)

RBB:	10549368(ND2)

TFN:	18985073(ND2)

CJC:	22203901(ND2)

SBQ:	13228912(ND2)

ANAN:

13230267(ND2)

CSYR:

7944462(ND2)

MMUR:

26823994(ND2)

LCAT:

68929177(ND2)

PCOQ:

6458121(ND2)

MMU:	17717(ND2)

MCAL:

20832243(ND2)

MPAH:

36165352(ND2)

RNO:	26194(ND2)

MCOC:

34682993(ND2)

MUN:	18129806(ND2)

CGE:	3979184(ND2)

MAUA:

8457924(ND2)

PROB:

30213866(BOP69_gp12)

PLEU:

36275547(ND2)

NGI:	15088424(ND2)

HGL:	10201215(ND2)

CPOC:

808632(ND2)

CCAN:

31082897(ND2)

ITI:	24576612(ND2)

OCU:	808230(ND2)

OPI:	2717281(ND2)

GVR:	804979(ND2)

CFA:	804477(ND2)

VVP:	4355758(ND2)

VLG:	23629747(ND2)

NPO:	8690241(ND2)

AML:	5179725(ND2)

UMR:	804862(ND2)

UAR:	804834(ND2)

LLV:	71922406(ND2)

MNP:	20466139(ND2)

NVS:	14841840(ND2)

EJU:	805011(ND2)

ZCA:	4355795(ND2)

MLX:	4355871(ND2)

LWW:	4355833(ND2)

FCA:	807935(ND2)

PYU:	26129867(ND2)

PCOO:

11473379(ND2)

PBG:	26129487(ND2)

PVIV:

26129639(ND2)

LGF:	26130209(ND2)

AJU:	2654019(ND2)

PPAD:

6262376(ND2)

PUC:	6262405(ND2)

PLEZ:

26129525(ND2)

HHV:	14842156(ND2)

BTA:	3283878(ND2)

BOM:	22161767(ND2)

BIU:	2885976(ND2)

BJV:	7901808(ND2)

BBUB:

56055849(ND2)

CHX:	1485857(ND2)

OAS:	808250(ND2)

OCAN:

11029997(ND2)

BTAX:

8250973(ND2)

CSUM:

14841686(ND2)

ODA:	11452039(ND2)

CCAD:

59433132(ND2)

MREE:

805172(ND2)

OVR:	10322914(ND2)

MBEZ:

7872543(ND2)

SSC:	808502(ND2)

CFR:	5326218(ND2)

CBAI:

5309937(ND2)

CDK:	5618961(ND2)

VPC:	809424(ND2)

BMUS:

807736(ND2)

LVE:	3802093(ND2)

OOR:	72909413(ND2)

LALB:

2658631(ND2)

DLE:	31412980(ND2)

PCAD:

809419(ND2)

ECB:	807844(ND2)

EPZ:	19019453(ND2)

EAI:	808059(ND2)

MYB:	20964693(ND2)

MYD:	22203929(ND2)

MMYO:

26889520(ND2)

MLF:	27214812(ND2)

DRO:	17046643(ND2)

AJM:	808337(ND2)

PDIC:

74550846(ND2)

HAI:	13539866(ND2)

PALE:

17963485(ND2)

MJV:	24019670(ND2)

TOD:	38289013(D9W85_mgp12)

LAV:	808792(ND2)

ETF:	802331(ND2)

DNM:	808135(ND2)

MDO:	3074668(ND2)

GAS:	63652830(ND2)

SHR:	13826439(ND2)

AFZ:	65342074(ND2)

PCW:	4108303(ND2)

TVP:	803527(ND2)

OAA:	808700(ND2)

GGA:	39116929(ND2)

PCOC:

10609897(ND2)

MGP:	5848009(ND2)

CJO:	804667(ND2)

LMUT:

31079460(ND2)

NMEL:

32282784(ND2)

APLA:

5405821(ND2)

ACYG:

18887299(ND2)

CATA:

7996698(ND2)

AFUL:

19909396(ND2)

TGU:	3950791(ND2)

LSR:	26897962(ND2)

SCAN:

37275771(ND2)

PMOA:

20355697(ND2)

OTC:	22548459(ND2)

PRUF:

17674389(ND2)

FAB:	16027866(ND2)

PHI:	9480993(ND2)

PMAJ:

39089578(ND2)

CCW:	71712374(ND2)

ACOE:

60235410(ND2)

MMEA:

130587654 20357133(ND2)

SATI:

5846208(ND2)

FPG:	808588(ND2)

FCH:	23808610(ND2)

AGEN:

7256438(ND2)

EGZ:	18985248(ND2)

NNI:	4108699(ND2)

PADL:

26737704(ND2)

GSTE:

3416061(ND2)

CBOY:

809231(ND2)

CLV:	8889996(ND2)

RTD:	84348647(ND2)

AROW:

62676602(ND2)

NPD:	62676503(ND2)

DNE:	803267(ND2)

ASN:	806141(ND2)

AMJ:	808246(ND2)

CPOO:

4108091(ND2)

GGN:	4178389(ND2)

PSS:	2943118(ND2)

CIZ:	25099102(ND2)

CMY:	808652(ND2)

CCAY:

11747771(ND2)

CPIC:

18982995(ND2)

CABI:

60253665(ND2)

ACS:	6385980(ND2)

PVT:	3338343(ND2)

PBI:	YP_008083600

PMUR:

15822631(ND2)

APRI:

131195785

PMUA:

7056461(ND2)

ZVI:	24146095(YC27_gp12)

GJA:	26044422(ND2)

EMC:	30861812(ND2)

XLA:	2642087(ND2)

XTR:	3283493(ND2)

NPR:	24020212(ND2)

ACAT:

17427714(ND2)

PADS:

41662619(ND2)

BGAR:

4356059(ND2)

MUO:	18490089(ND2)

GSH:	14469870(ND2)

DRE:	140532(ND2)

SRX:	24419155(ND2)

SANH:

24419945(ND2)

SGH:	8382163(ND2)

CCAR:

807766(ND2)

CGIB:

9222065(ND2)

PTET:

5787387(ND2)

LROH:

12079591(ND2)

OMC:	18668118(ND2)

PPRM:

26048337(ND2)

RKG:	130077634 130077637 130077640 130077643

MAMB:

5912303(ND2)

CIDE:

5857718(ND2)

CERY:

20160548(ND2)

MASI:

3131141(ND2)

TROS:

14048436(ND2)

TDW:	36952185(ND2)

MANU:

6879710(ND2)

PDAB:

18668397(ND2)

IPU:	804883(ND2)

IFU:	26118480(ND2)

PHYP:

16216568(ND2)

SMEO:

10079898(ND2)

TVC:	10079787(ND2) 132858794

CGAR:

128512075 25103331(ND2)

TRN:	134307553 134307559 134307591 134307598

CHAR:

5228444(ND2)

TRU:	805217(ND2)

TFS:	19524532(ND2)

TNG:	BAE79218(ND2)

LCO:	7095382(ND2)

NCC:	10752023(ND2)

PGEO:

67284287(ND2)

EMAC:

30862031(ND2)

ELY:	7095517(ND2)

EFO:	14412328(ND2)

PLEP:

4363283(ND2)

SLUC:

23629803(ND2)

ESP:	40141429(ND2)

PFLV:

14048210(ND2)

AFB:	13230429(ND2)

PSWI:

72130134(ND2)

MSAM:

4100026(ND2)

SCHU:

10965120(ND2)

EARM:

8382041(ND2)

CUD:	8774885(ND2)

MZE:

26037637

ONL:	8677312(ND2)

OAU:	8745940(ND2)

OLA:	805440(ND2)

OML:	13540108(ND2)

CSAI:

804088(ND2)

XMA:	6986209(ND2)

XCO:	26048185(ND2)

XHE:	8302519(ND2)

PRET:

19590714(ND2)

GAF:	805450(ND2)

CVG:	26048375(ND2)

CTUL:

26129145(ND2)

NFU:	7256389(ND2)

KMR:	804467(ND2)

AOCE:

4850675(ND2)

CSEM:

7996492(ND2)

POV:	808838(ND2)

SSEN:

4266846(ND2)

HHIP:

5405721(ND2)

HSP:	5405779(ND2)

SMAU:

8382073(ND2)

LCF:	3703588(ND2)

SDU:	11669687(ND2)

XGL:	7871600(ND2)

HCQ:	14658011(ND2)

SBIA:

35996581(ND2)

PTAO:

74193744(ND2)

BPEC:

YP_004935132.1

MALB:

803938(ND2)

BSPL:

23631936(ND2)

SJO:	8703819(ND2)

GMH:	808445(ND2)

SASA:

808316(ND2)

STRU:

19099176(ND2)

OTW:	KEF73_p12(ND2)

OMY:	807979(ND2)

OGO:	6383212(ND2)

ONE:	4555711(ND2)

OKI:	4955087(ND2)

OKE:	12486860(ND2)

OMM:	4657586(ND2)

SALP:

808545(ND2)

SNH:	35115214(ND2)

CCLU:

14842632(ND2)

ELS:	806646(ND2)

SFM:	3416105(ND2)

AANG:

3190266(ND2)

LOC:	807197(ND2)

PSPA:

805405(ND2)

ARUT:

17097819(ND2)

LCM:	808084(ND2)

CMK:	9385345(ND2)

RTP:	18267177(ND2)

CPLA:

7768743(ND2)

SCAU:

808291(ND2)

LERI:

11452179(ND2)

HAKA:

15333366(ND2)

PMRN:

807814(ND2)

LRJ:	9385088(ND2)

BFO:	808738(ND2)

BBEL:

806240(ND2)

SCLV:

36165638(ND2)

SPU:	2652717(ND2)

LVG:	36941437(ND2)

AJJ:	7802879(ND2)

APLC:

110990861 3907680(ND2)

AAMU:

3239010(ND2)

SKO:	3703612(ND2)

DME:	Dmel_CG34063(ND2)

DSE:	2760951(ND2)

DSI:

DYA:

DAN:

26515184

DPO:	117185108 26532037

DMN:	117194308 117194314

DGR:

116806150

CCAT:

110118211 808525(ND2)

BOD:	2717264(ND2)

BDR:	4657582(ND2)

AOQ:	79023071(ND2)

TDA:

119688821

MDE:	20358592(ND2)

LSQ:	5469274(ND2)

ECOE:

35199145(ND2)

HIS:	33350925(ND2)

AGA:	85940915(ND2)

ACOZ:

26121317(ND2)

AARA:

26121203(ND2)

AMER:

26121507(ND2)

AMAP:

73620763(ND2)

AFUN:

76054167(ND2)

AMOU:

73620839(ND2)

AMRS:

73620801(ND2)

ANIL:

73620915(ND2)

ADAR:

73620991(ND2)

AAG:	33307554(ND2)

AALB:

3260123(ND2)

CQU:

CPII:

10200340(ND2)

CBRI:

87696356(ND2)

BCOO:

119084560

PPAP:

26044645(ND2)

ACER:

9385650(ND2)

ALAB:

34829157(ND2)

AFLR:

15822495(ND2)

SOC:	9977801(ND2)

VEM:	27912153(ND2)

LHU:	42265463(ND2)

VVE:	33194923(ND2)

AGIF:

63649813(ND2)

CCIN:

7872304(ND2)

TCA:	803823(ND2)

TMOL:

138140765

SOY:	28481398(ND2)

ATD:	34926354(ND2)

CSET:

123313380

AGB:	4171596(ND2)

LDC:

111506462

APLN:

28479666(ND2)

BMOR:

809265(ND2)

BMAN:

804652(ND2)

MSEX:

5848759(ND2)

DPL:	AGL76298(ND2)

BANY:

128199787 128199790

PMAC:

106711768 13080340(ND2)

PPOT:

106110404 20159566(ND2)

PXU:	106121442 26836900(ND2)

PRAP:

11030477(ND2)

PBX:

123718343

PNAP:

125062050 60241340(ND2)

ZCE:

119839406

HAW:	9977724(ND2)

HZE:	124645587 124645588 71203121(ND2)

TNL:	113502838 113502922 44149129(ND2)

SLIU:

17427408(ND2)

ATRA:

26281588(ND2)

GMW:	26376085(ND2)

ECLR:

140757099 140757101

PXY:	20834458(ND2)

PGW:	73956675(ND2)

CSTB:

134752857

API:	7055887(ND2)

DNX:	17428421(ND2)

AGS:	19909112(ND2)

BTAB:

3077230(ND2)

DCI:	27914400(ND2)

CLEC:

27787560(ND2)

HHAL:

8457894(ND2)

NLU:	16216538(ND2)

LDA:	7996611(ND2)

HVI:	3332280(ND2)

MQU:	32891616(ND2)

FOC:	YP_006576362

TPAL:

38092121(ND2)

ZNE:	20004831(ND2)

PAME:

138694189 138694191

SGRE:

73491788(ND2)

DPX:	AAD33230(ND2)

DMK:	24147202(ND2)

AFRA:

807795(ND2)

PVM:	138863176 138865821 5333216(ND2)

PJA:	3416047(ND2)

PCHN:

5333404(ND2)

PMOO:

808982(ND2)

HAME:

10743683(ND2)

PCLA:

11763608(ND2)

CQD:	17728534(ND2)

PTRU:

1482829(ND2)

SPRM:

7768781(ND2)

ESN:	3355546(ND2)

MNZ:	10200255(ND2)

MRJ:	3293138(ND2)

PORN:

10094409(ND2)

HAZT:

38169096(ND2)

OOT:	9481018(ND2)

TCF:	4788313(ND2)

DSV:	23630430(ND2)

RSAN:

808361(ND2)

RMP:	18250947(ND2)

VDE:	806161(ND2)

TUT:	6164214(ND2)

DPTE:

7564655(ND2)

ABRU:

19591992(ND2)

LPOL:

803776(ND2)

CEL:	KEF34_p08(ND2)

CBR:

NAI:	804825(ND2)

LOA:

TSP:

PCAN:

19909190(ND2)

LSAX:

28261533(ND2)

BARL:

17960497(ND2)

BGT:	2746313(ND2)

HRF:	35985181(ND2)

HRJ:	2846690(ND2)

CRG:	808826(ND2)

CANU:

7865911(ND2)

MYI:	4910448(ND2)

MMER:

55289767(ND2)

RPHI:

29141297(ND2)

OBI:	106869121 27205956(ND2)

OSN:	62676621(ND2)

LAK:	C2G87_mgp12(ND2)

SMM:

127107514 127107516 127119353

SHX:	4097436(ND2)

ATEN:

41854790(ND2)

ADF:	17674589(ND2)

PDAM:

5580395(ND2)

SPIS:

6798781(ND2)

DGT:	8656272(ND2)

XEN:	124455309 124455316 124455317

HMG:	6904228(ND2)

HSY:	130626408 130626440

RES:	33911776(ND2)

TAD:	TradoM_p10(ND2)

AQU:	4794351(ND2)

ATH:	AT2G07689 DA397_mgp31(nad2)

CRB:	40490664(nad2)

EUS:	EUTSA_v10015951mg

BRP:	56141084(nad2)

BNA:	4237887(nad2)

RSZ:	13630161(nad2)

CPAP:

7441423(nad2)

CIT:	36487064(nad2)

GRA:	27429583(nad2)

GAB:	33134422(nad2)

HSYR:

120202671

EGR:	120288250 38466617(nad2)

RARG:

115732823 125313381

GMX:	15308633(nad2)

PVU:	42317461(nad2)

VRA:

106779391

VAR:	15382820(nad2)

VUN:

114192993

CCAJ:

109793480 109793583

MTR:	120577846 26974329(nad2)

TPRA:

55290666(nad2)

PSAT:

VVO:

ADU:

AHF:

PCIN:

PMUM:

MDM:	13630220(nad2)

MSYL:

73938917(nad2)

ZJU:	27215290(nad2)

MNT:	39338982(nad2)

CSAV:

27215502(nad2)

CSV:	11123895(nad2)

CMO:	127146615 127146702 127147997 127148203 127149812 127150905 127150986

BHJ:

120070876

MCHA:

111025687

RCU:	10221400(nad2)

MEAN:

126655377

HBR:

110654472

MESC:

42317545(nad2)

POP:

PEU:

QSU:

QLO:

TWL:

VVI:	7498551(nad2)

VRI:

117923747

SPEN:

34925969(nad2)

SOT:

102603210

CANN:

124886983 19988969(nad2)

NTA:	3205197(nad2)

NSY:	27214829(nad2) 27214857(nad2) 27214864(nad2)

NAU:	35198932(nad2)

INI:	29082055(nad2)

SIND:

105155298 110011718

SSPL:

121789896

SMIL:

18126413(nad2)

APAN:

127253053

ECAD:

122584409

LSV:	40498736(nad2)

CCAV:

112506054

DCR:	88614165(nad2)

AGRV:

68216399(nad2)

CSIN:

40867533(nad2)

AEW:	88577598(nad2)

DLT:

127793303

BVG:	809516(orf300) 809520(nad2)

SOE:	110802001 33876625(nad2)

CQI:	39331955(nad2)

SLAF:

9725739(nad2)

NNU:	28482668(nad2)

MING:

122081814

TSS:	122647145 122647659

OSA:	6450140(nad2)

DOSA:

nad2

TAES:

123040764 123048612 123060510 123091833 123102063 123102877 123102881 123144429 123146145 123156862 123165021 123180197 34688810(nad2)

TUA:	125519794 125522492 125530740 125531833 125536610 125550437 125551606

HVG:

123420470

SBI:	4306038(nad2)

SVS:

117848589

PVIR:

120693837 120694099

PDA:	11542591(nad2)

PEQ:	110030394 110036994

MSIN:

131219080

NCOL:

36487377(nad2)

CJF:	131077509 131873307

SMO:	SELMODRAFT_138433

PPP:	3989055(nad2)

CRE:	ChrepMp05(nad2)

CSL:	CospCoM_p24(nad2)

CVR:	OJ20_p17(nad2)

APRO:

ChprMp016(nad2)

OTA:	OstapMp34(nad2)

BPG:	BathyMg00060(nad2)

MIS:	MicpuN_mit23(nad2)

CCP:	ChcroMp15(nad2)

DHA:

LBG:	89432249(nad2)

CAL:	CaalfMp09(NAD2)

CLUS:

16792612(nad2)

YLI:	802601(nd2)

NCR:

NCU16006

PAN:	PoanfMp04(nad2)

CTHR:

CTHT_m000270

SSCK:

SPSK_11046

FGR:	GizefMp03(nad2)

PTKZ:

MRV25_mgp15(nad2)

VAL:	VDBG_17006

CLUP:

AYB75_mgp06(nad2)

SSL:	SS1G_20043

ANI:	ANID_20002

ANG:	Asnifp16(nad2)

ALUC:

EJ508_mgp02(nad2)

PNO:	SNOGp13(nad2)

BZE:	COCCADRAFT_113372

BOR:	COCMIDRAFT_111428

MRT:	D9L16_mgp15(nad2)

PSTR:

EFH26_mgp09(nad2)

DDI:	DidioMp03(nad2)

TET:	TepyoMp11(nad2)

PIF:	PITG_23229

PSOJ:

PhsooMp17(nad2)

MHEY:

H2LOC_010245

SRC:	M271_20175

Reference

PMID:9475751

Authors

Wise CA, Sraml M, Easteal S

Title

Departure from neutrality at the mitochondrial NADH dehydrogenase subunit 2 gene in humans, but not in chimpanzees.

Journal

Genetics 148:409-21 (1998)

Sequence

[hsa:4536]

LinkDB

ORTHOLOGY: K03880

Entry

K03880                      KO

Symbol

ND3

Name

NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00473

Mitochondrial complex I deficiency

H01355

Kearns-Sayre syndrome

H01365

Leber hereditary optic neuropathy and dystonia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
  09159 Environmental adaptation
   04714 Thermogenesis
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
   05012 Parkinson disease
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
   05014 Amyotrophic lateral sclerosis
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
   05016 Huntington disease
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
   05020 Prion disease
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
   05022 Pathways of neurodegeneration - multiple diseases
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03880  ND3; NADH-ubiquinone oxidoreductase chain 3
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03880  ND3; NADH-ubiquinone oxidoreductase chain 3

Other DBs

GO:

TC:

Genes

HSA:

4537(ND3)

PTR:	807870(ND3)

PPS:	807879(ND3)

GGO:	6742686(ND3)

PON:	808479(ND3)

PPYG:

807902(ND3)

NLE:	16545229(ND3)

SSYN:

9072794(ND3)

MCC:	2846622(ND3)

MCF:	7857744(ND3)

CSAB:

4097495(ND3)

CATY:

26408647(ND3)

PANU:

14444636(ND3)

TGE:	14216788(ND3)

RRO:	4171541(ND3)

RBB:	10549374(ND3)

TFN:	18985079(ND3)

CJC:	22203907(ND3)

SBQ:	13228918(ND3)

ANAN:

13230273(ND3)

CSYR:

7944463(ND3)

MMUR:

26823995(ND3)

LCAT:

68929186(ND3)

PCOQ:

6458120(ND3)

MMU:	17718(ND3)

MCAL:

20832249(ND3)

MPAH:

36165337(ND3)

RNO:	26199(ND3)

MCOC:

34683008(ND3)

MUN:	18129811(ND3)

CGE:	3979190(ND3)

MAUA:

8457930(ND3)

PROB:

30213875(BOP69_gp06)

PLEU:

36275556(ND3)

PMAV:

39105344(ND3)

NGI:	15088430(ND3)

HGL:	10201214(ND3)

CPOC:

808639(ND3)

CCAN:

31082912(ND3)

ITI:	24576621(ND3)

OCU:	808221(ND3)

OPI:	2717278(ND3)

GVR:	804971(ND3)

CFA:	804481(ND3)

VVP:	4355759(ND3)

VLG:	23629753(ND3)

NPO:	8690247(ND3)

AML:	5179736(ND3)

UMR:	804863(ND3)

UAR:	804845(ND3)

LLV:	71922421(ND3)

MNP:	20466145(ND3)

NVS:	14841846(ND3)

EJU:	805018(ND3)

ZCA:	4355796(ND3)

MLX:	4355872(ND3)

LWW:	4355834(ND3)

FCA:	807938(ND3)

PYU:	26129876(ND3)

PCOO:

11473385(ND3)

PBG:	26129496(ND3)

PVIV:

26129648(ND3)

LGF:	26130218(ND3)

AJU:	2654022(ND3)

PPAD:

6262373(ND3)

PUC:	6262404(ND3)

PLEZ:

26129534(ND3)

HHV:	14842162(ND3)

BTA:	3283884(ND3)

BOM:	22161773(ND3)

BIU:	2885978(ND3)

BJV:	7901814(ND3)

BBUB:

56055858(ND3)

CHX:	1485863(ND3)

OAS:	808255(ND3)

OCAN:

11030003(ND3)

BTAX:

8250967(ND3)

CSUM:

14841692(ND3)

ODA:	11452045(ND3)

CCAD:

59433141(ND3)

MREE:

805177(ND3)

OVR:	10322919(ND3)

MBEZ:

7872549(ND3)

SSC:	808508(ND3)

CFR:	5326226(ND3)

CBAI:

5309944(ND3)

CDK:	5618962(ND3)

VPC:	809423(ND3)

BMUS:

807741(ND3)

LVE:	3802099(ND3)

OOR:	72909422(ND3)

LALB:

2658644(ND3)

DLE:	31412989(ND3)

PCAD:

809409(ND3)

ECB:	807855(ND3)

EPZ:	19019452(ND3)

EAI:	808060(ND3)

MYB:	20964699(ND3)

MYD:	22203921(ND3)

MMYO:

26889529(ND3)

MLF:	27214821(ND3)

DRO:	17046637(ND3)

AJM:	808335(ND3)

PDIC:

74550855(ND3)

HAI:	13539872(ND3)

PALE:

17963500(ND3)

MJV:	24019676(ND3)

TOD:	38289022(D9W85_mgp06)

LAV:	808786(ND3)

ETF:	802332(ND3)

DNM:	808128(ND3)

MDO:	3074658(ND3)

GAS:	63652839(ND3)

SHR:	13826438(ND3)

AFZ:	65342083(ND3)

PCW:	4108304(ND3)

TVP:	803532(ND3)

OAA:	808710(ND3)

GGA:	39116938(ND3)

PCOC:

10609902(ND3)

MGP:	5848008(ND3)

CJO:	804659(ND3)

LMUT:

31079469(ND3)

NMEL:

32282793(ND3)

APLA:

5405822(ND3)

ACYG:

18887305(ND3)

CATA:

7996704(ND3)

AFUL:

19909402(ND3)

TGU:	3950797(ND3)

LSR:	26897971(ND3)

SCAN:

37275793(ND3)

PMOA:

20355703(ND3)

OTC:	22548465(ND3)

PRUF:

17674381(ND3)

FAB:	16027881(ND3)

PHI:	9480999(ND3)

PMAJ:

39089587(ND3)

CCW:	71712352(ND3)

ACOE:

60235425(ND3)

MMEA:

20357139(ND3)

SATI:

5846213(ND3)

FPG:	808587(ND3)

FCH:	23808604(ND3)

AGEN:

7256436(ND3)

EGZ:	18985254(ND3)

NNI:	4108700(ND3)

PADL:

26737705(ND3)

GSTE:

3416054(ND3)

CBOY:

809239(ND3)

CLV:	8890003(ND3)

RTD:	84348662(ND3)

AROW:

62676606(ND3)

NPD:	62676471(ND3)

DNE:	803262(ND3)

ASN:	806131(ND3)

AMJ:	808236(ND3)

CPOO:

4108092(ND3)

GGN:	4178390(ND3)

PSS:	2943125(ND3)

CIZ:	25099108(ND3)

CMY:	808647(ND3)

CCAY:

11747798(ND3)

CPIC:

18983001(ND3)

CABI:

60253695(ND3)

ACS:	6385979(ND3)

PVT:	3338374(ND3)

PBI:	YP_008083606

PMUR:

15822637(ND3)

PMUA:

7056467(ND3)

ZVI:	24146104(YC27_gp06)

GJA:	26044431(ND3)

EMC:	30861821(ND3)

XLA:	2642085(ND3)

XTR:	3283499(ND3)

NPR:	24020219(ND3)

ACAT:

17427723(ND3)

PADS:

41662607(ND3)

BGAR:

4356064(ND3)

MUO:	18490112(ND3)

GSH:	14469876(ND3)

DRE:	140533(ND3)

SRX:	24419171(ND3)

SANH:

24419970(ND3)

SGH:	8382169(ND3)

CCAR:

807771(ND3)

CGIB:

9222071(ND3)

PTET:

5787381(ND3)

LROH:

12079597(ND3)

OMC:	18668124(ND3)

PPRM:

26048346(ND3)

MAMB:

5912299(ND3)

CIDE:

5857711(ND3)

CERY:

20160552(ND3)

MASI:

3131137(ND3)

TROS:

14048442(ND3)

TDW:	36952194(ND3)

MANU:

6879716(ND3)

PDAB:

18668403(ND3)

IPU:	804878(ND3)

IFU:	26118489(ND3)

PHYP:

16216574(ND3)

SMEO:

10079904(ND3)

TVC:	10079793(ND3)

CGAR:

25103340(ND3)

CHAR:

5228439(ND3)

ASAD:

9978352(ND3)

TRU:	805224(ND3)

TFS:	19524538(ND3)

TNG:	BAE79224(ND3)

LCO:	7095388(ND3)

NCC:	10752029(ND3)

PGEO:

67284265(ND3)

EMAC:

30862046(ND3)

ELY:	7095523(ND3)

EFO:	14412334(ND3)

PLEP:

4363289(ND3)

SLUC:

23629809(ND3)

ESP:	40141438(ND3)

PFLV:

14048225(ND3)

AFB:	13230435(ND3)

PSWI:

72130143(ND3)

MSAM:

4100032(ND3)

SCHU:

10965122(ND3)

EARM:

8382042(ND3)

CUD:	8774891(ND3)

MZE:

26037646

ONL:	8677318(ND3)

OAU:	8745946(ND3)

OLA:	805439(ND3)

OML:	13540114(ND3)

CSAI:

804083(ND3)

XMA:	6986208(ND3)

XCO:	26048194(ND3)

XHE:	8302513(ND3)

PRET:

19590708(ND3)

GAF:	805455(ND3)

CVG:	26048384(ND3)

CTUL:

26129154(ND3)

NFU:	7256397(ND3)

KMR:	804472(ND3)

AOCE:

4850674(ND3)

CSEM:

7996486(ND3)

POV:	808844(ND3)

SSEN:

4266847(ND3)

HHIP:

5405697(ND3)

HSP:	5405797(ND3)

SMAU:

8382079(ND3)

LCF:	3703594(ND3)

SDU:	11669693(ND3)

XGL:	7871599(ND3)

HCQ:	14658017(ND3)

SBIA:

35996590(ND3)

PTAO:

74193759(ND3)

BPEC:

YP_004935138.1

MALB:

803929(ND3)

BSPL:

23631934(ND3)

SJO:	8703818(ND3)

GMH:	808452(ND3)

SASA:

808308(ND3)

STRU:

19099182(ND3)

OTW:	KEF73_p06(ND3)

OMY:	807972(ND3)

OGO:	6383208(ND3)

ONE:	4555716(ND3)

OKI:	4955079(ND3)

OKE:	12486866(ND3)

OMM:	4657594(ND3)

SALP:

808553(ND3)

SNH:	35115223(ND3)

CCLU:

14842638(ND3)

ELS:	806654(ND3)

SFM:	3416098(ND3)

AANG:

3190260(ND3)

LOC:	807199(ND3)

PSPA:

805403(ND3)

ARUT:

17097825(ND3)

LCM:	808090(ND3)

CMK:	9385351(ND3)

RTP:	18267183(ND3)

CPLA:

7768749(ND3)

SCAU:

808301(ND3)

LERI:

11452185(ND3)

HAKA:

15333372(ND3)

PMRN:

807807(ND3)

LRJ:	9385086(ND3)

BFO:	808731(ND3)

BBEL:

806236(ND3)

SPU:	2652723(ND3)

LVG:	36941441(ND3)

AJJ:	7802873(ND3)

APLC:

3907681(ND3)

AAMU:

3239017(ND3)

SKO:	3703606(ND3)

DME:	Dmel_CG34076(ND3)

DSE:	2760946(ND3)

DSI:

DYA:

CCAT:

808524(ND3)

BOD:	2717256(ND3)

BDR:	4657571(ND3)

AOQ:	79023084(ND3)

MDE:	20358595(ND3)

LSQ:	5469262(ND3)

ECOE:

35199152(ND3)

HIS:	33350932(ND3)

AGA:	85940922(ND3)

ACOZ:

26121324(ND3)

AARA:

26121210(ND3)

AMER:

26121514(ND3)

AMAP:

73620776(ND3)

AFUN:

76054174(ND3)

AMOU:

73620852(ND3)

AMRS:

73620814(ND3)

ANIL:

73620928(ND3)

ADAR:

73621004(ND3)

AAG:	33307561(ND3)

AALB:

3260120(ND3)

CQU:

CPII:

10200333(ND3)

CBRI:

87696338(ND3)

PPAP:

26044652(ND3)

ACER:

9385643(ND3)

ALAB:

34829164(ND3)

AFLR:

15822488(ND3)

SOC:	9977794(ND3)

VEM:	27912156(ND3)

LHU:	42265446(ND3)

VVE:	33194929(ND3)

AGIF:

63649826(ND3)

CCIN:

7872295(ND3)

TCA:	803821(ND3)

TMOL:

138140763

SOY:	28481405(ND3)

ATD:	34926369(ND3)

AGB:	4171602(ND3)

APLN:

28479679(ND3)

BMOR:

809257(ND3)

BMAN:

804648(ND3)

MSEX:

5848752(ND3)

DPL:	AGL76304(ND3)

PMAC:

13080346(ND3)

PPOT:

20159559(ND3)

PXU:	106113038 26836904(ND3)

PRAP:

11030483(ND3)

PNAP:

60241347(ND3)

HAW:	9977717(ND3)

HZE:	71203134(ND3)

TNL:	44149103(ND3)

SLIU:

17427399(ND3)

ATRA:

26281596(ND3)

GMW:	26376092(ND3)

PXY:	20834451(ND3)

PGW:	73956682(ND3)

CFUM:

36490485(ND3)

API:	7055880(ND3)

DNX:	17428414(ND3)

AGS:	19909105(ND3)

BTAB:

3077224(ND3)

DCI:	27914407(ND3)

CLEC:

27787561(ND3)

HHAL:

8457887(ND3)

NLU:	16216531(ND3)

LDA:	7996604(ND3)

HVI:	3332279(ND3)

MQU:	32891623(ND3)

FOC:	YP_006576371

TPAL:

38092108(ND3)

ZNE:	20004822(ND3)

SGRE:

73491801(ND3)

DPX:

AAD33236

DMK:	24147209(ND3)

AFRA:

807797(ND3)

PVM:	5333208(ND3)

PJA:	3416048(ND3)

PCHN:

5333408(ND3)

PMOO:

808983(ND3)

HAME:

10743676(ND3)

PCLA:

11763615(ND3)

CQD:	17728518(ND3)

PTRU:

1482830(ND3)

SPRM:

7768774(ND3)

ESN:	3355541(ND3)

MNZ:	10200248(ND3)

MRJ:	3293134(ND3)

PORN:

10094401(ND3)

HAZT:

38169111(ND3)

OOT:	9481011(ND3)

TCF:	4788306(ND3)

DSV:	23630422(ND3)

RSAN:

808369(ND3)

RMP:	18250940(ND3)

VDE:	806160(ND3)

TUT:	6164205(ND3)

DPTE:

7564649(ND3)

LPOL:

803784(ND3)

CEL:	KEF34_p02(ND3)

CBR:

NAI:	804824(ND3)

LOA:

TSP:

HRO:	HELRODRAFT_147263 HELRODRAFT_83278

PCAN:

19909189(ND3)

LSAX:

28261532(ND3)

BARL:

17960496(ND3)

BGT:	2746314(ND3)

HRF:	35985178(ND3)

HRJ:	2846691(ND3)

CRG:	808834(ND3)

CANU:

7865915(ND3)

MYI:	4910449(ND3)

YBA:

132552998

MMER:

55289781(ND3)

RPHI:

29141291(ND3)

OBI:	27205954(ND3)

OSN:	62676632(ND3)

LJP:	79134712(ND3)

LAK:	C2G87_mgp05(ND3)

SMM:

127243665 127244389 127244554 127264281

SHX:	4097439(ND3)

EGL:	41697857(nad3)

ATEN:

41854779(ND3)

ADF:	17674596(ND3)

DGT:	8656269(ND3)

HMG:	6904242(ND3)

RES:	33911767(ND3)

TAD:	TradoM_p20(ND3)

AQU:	4794358(ND3)

ATH:	AT2G07751 DA397_mgp14(nad3)

CRB:	40490674(nad3)

BRP:	56141050(nad3)

BNA:	4237970(nad3)

RSZ:	13630152(nad3)

CPAP:

110811535 7441453(nad3)

CIT:	36487058(nad3)

PVY:

116120443

GRA:	27429577(nad3)

GHI:	24679495(nad3)

GAB:	128285190 33134407(nad3)

HSYR:

120174379

EGR:	120293425 38466610(nad3)

RARG:

125313451 125313491

GMX:	15308563(nad3)

GSJ:	114381770 38334428(nad3)

PVU:	42317442(nad3)

VAR:	108328560 15382775(nad3)

VUN:

114172421

VUM:

124827006

CCAJ:

109794153

MTR:	26974348(nad3)

TPRA:

55290704(nad3)

VVO:	131620563 131637802

ADU:	127741637 127743779 127744546 127744549 127744643 127744646

PCIN:

129294883

PPER:

109946550

MDM:	114825879 13630211(nad3)

MSYL:

126630203 73938899(nad3)

ZJU:	125420105 27215256(nad3)

MNT:	39338972(nad3)

CSV:	11123864(nad3)

CMO:

127151218

BHJ:	120084052 120088816 120089847

CPEP:

111804780

RCU:	10221422(nad3)

HBR:

110668638

MESC:

42317524(nad3)

POP:

127905547

QLO:

115986346

CSAA:

142634143

VVI:	7498617(nad3)

SLY:	138339383 34678261(nad3)

SPEN:

34925990(nad3)

CANN:

19989078(nad3)

LBB:

132628841

NTA:	3205228(nad3) 3205293(nad3)

NSY:	27214840(nad3) 27214872(nad3)

NTO:

117281622

NAU:	35198920(nad3)

INI:	29082058(nad3)

SMIL:

18126381(nad3)

SHIS:

125209450

APAN:

HPUM:

140866737

HAN:	118480619 18250973(nad3)

ECAD:

122584418 122584442 122585904

LSV:	122194656 122196600 40498723(nad3)

CCAV:

112508223

DCR:	135150740 88614170(nad3)

AGRV:

68216255(nad3) 68216396(nad3)

CSIN:

40867539(nad3)

RVL:

131326193

AEW:	88577567(nad3)

CFLO:

132280800 132289417 132289418 132289419

BVG:	809522(nad3)

SOE:	33876573(nad3)

CQI:	39331950(nad3)

ATRI:

130827025

SLAF:

9725756(nad3)

NNU:	28482682(nad3)

MING:

122088858

TSS:	122647085 122647150

OSA:	6450168(nad3)

DOSA:

nad3

OGL:

127762845

ATS:	120962441 120962845

TDC:	119267845 119281453 119287974 119298826 119301650 119305087 119305296 119320156 119330349 119330818 119331025 119360889

TAES:

123039220 123044167 123044193 123055368 123060962 123096778 123104777 123115836 123120122 123121382 123124396 123125696 123134074 123137272 123148302 123167354 123175587 123180905 34688769(nad3)

TUA:	125523200 125525142 125530880 125533751 125539733 125541803 125549475 125554005

HVG:	123404121 123416981 123416982 123418188 123418210 123426648 123427159 123430166 123442469 123442474

LPER:

127312611

SBI:	4306053(nad3)

PVIR:

120693848 120693849 120693870 120694122 120703472 120703539

PHAI:

112880714

PAUA:

133897940

PDA:	11542580(nad3)

DCT:

110107522

PEQ:

110020095

AOF:

109822622

NCOL:

116267892 36487370(nad3)

ATR:

110006942

CJF:

131066031

SMO:	SELMODRAFT_9546

PPP:	3989056(nad3)

VCN:	VOLCADRAFT_82032(nuo3)

CSL:	CospCoM_p13(nad3)

CVR:	OJ20_p21(nad3)

APRO:

ChprMp004(nad3) F751_0125

OTA:	OstapMp16(nad3)

BPG:	BathyMg00155(nad3)

MIS:	MicpuN_mit79(nad3)

CCP:	ChcroMp13(nad3)

DHA:

LBG:	89432250(nad3)

CAL:	CaalfMp10(NAD3)

CLUS:

16792611(nad3)

YLI:	802603(nd3)

SLB:	AWJ20_5373

NCR:

NCU16007

PAN:	PoanfMp05(nad3)

CTHR:

CTHT_m000280

SSCK:

SPSK_11047

FGR:	GizefMp04(nad3)

CMT:

CCM_09677

PTKZ:

MRV25_mgp14(nad3)

VAL:	VDBG_17005

CLUP:

AYB75_mgp07(nad3)

SSL:	SS1G_20044

ANI:	ANID_20018

ANG:	Asnifp12(nad3)

ALUC:

EJ508_mgp06(nad3)

CPW:	90965850(nad3)

PNO:	SNOGp12(nad3)

BZE:	COCCADRAFT_46460

BOR:	COCMIDRAFT_43615

ABP:	AGABI1DRAFT48394(AGABI1DRAFT_48394)

MRT:	D9L16_mgp14(nad3)

PSTR:

EFH26_mgp08(nad3)

DDI:	DidioMp13(nad3)

DFA:	Difao_mp22(nad3)

TET:	TepyoMp26(nad3)

RSIN:

B6N60_00461

Reference

PMID:17152068

Authors

Sarzi E, Brown MD, Lebon S, Chretien D, Munnich A, Rotig A, Procaccio V

Title

A novel recurrent mitochondrial DNA mutation in ND3 gene is associated with isolated complex I deficiency causing Leigh syndrome and dystonia.

Journal

Am J Med Genet A 143A:33-41 (2007)
DOI:10.1002/ajmg.a.31565

Sequence

[hsa:4537]

LinkDB

ORTHOLOGY: K03881

Entry

K03881                      KO

Symbol

ND4

Name

NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00068

Leber hereditary optic atrophy

H00473

Mitochondrial complex I deficiency

H01355

Kearns-Sayre syndrome

H01365

Leber hereditary optic neuropathy and dystonia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
  09159 Environmental adaptation
   04714 Thermogenesis
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
   05012 Parkinson disease
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
   05014 Amyotrophic lateral sclerosis
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
   05016 Huntington disease
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
   05020 Prion disease
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
   05022 Pathways of neurodegeneration - multiple diseases
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03881  ND4; NADH-ubiquinone oxidoreductase chain 4
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03881  ND4; NADH-ubiquinone oxidoreductase chain 4

Other DBs

GO:

TC:

Genes

HSA:

4538(ND4)

PTR:	807863(ND4)

PPS:	807875(ND4)

GGO:	6742687(ND4)

PON:	808481(ND4)

PPYG:

807912(ND4)

NLE:	16545234(ND4)

SSYN:

9072799(ND4)

MCC:	2846630(ND4)

MCF:	7857746(ND4)

CSAB:

4097497(ND4)

CATY:

26408626(ND4)

PANU:

14444638(ND4)

TGE:	14216790(ND4)

RRO:	4171543(ND4)

RBB:	10549376(ND4)

TFN:	18985081(ND4)

CJC:	22203909(ND4)

SBQ:	13228910(ND4)

ANAN:

13230275(ND4)

CSYR:

7944470(ND4)

MMUR:

26823983(ND4)

LCAT:

68929165(ND4)

PCOQ:

6458127(ND4)

MMU:	17719(ND4)

MCAL:

20832251(ND4)

MPAH:

36165334(ND4)

RNO:	26201(ND4)

MCOC:

34683011(ND4)

MUN:	18129813(ND4)

CGE:	3979179(ND4)

MAUA:

8457932(ND4)

PROB:

30213853(BOP69_gp04)

PLEU:

36275535(ND4)

PMAV:

39105337(ND4)

NGI:	15088432(ND4)

HGL:	10201219(ND4)

CPOC:

808636(ND4)

CCAN:

31082915(ND4)

ITI:	24576624(ND4)

OCU:	808225(ND4)

OPI:	2717282(ND4)

GVR:	804968(ND4)

CFA:	804483(ND4)

VVP:	4355760(ND4)

VLG:	23629755(ND4)

NPO:	8690249(ND4)

AML:	5179726(ND4)

UMR:	804867(ND4)

UAR:	804839(ND4)

LLV:	71922424(ND4)

MNP:	20466147(ND4)

NVS:	14841848(ND4)

EJU:	805010(ND4)

ZCA:	4355797(ND4)

MLX:	4355873(ND4)

LWW:	4355835(ND4)

FCA:	807928(ND4)

PYU:	26129855(ND4)

PCOO:

11473377(ND4)

PBG:	26129475(ND4)

PVIV:

26129627(ND4)

LGF:	26130197(ND4)

AJU:	2654024(ND4)

PPAD:

6262382(ND4)

PUC:	6262403(ND4)

PLEZ:

26129513(ND4)

HHV:	14842164(ND4)

BTA:	3283886(ND4)

BOM:	22161775(ND4)

BIU:	2885973(ND4)

BJV:	7901816(ND4)

BBUB:

56055839(ND4)

CHX:	1485865(ND4)

OAS:	808257(ND4)

OCAN:

11030005(ND4)

BTAX:

8250969(ND4)

CSUM:

14841694(ND4)

ODA:	11452047(ND4)

CCAD:

59433123(ND4)

MREE:

805179(ND4)

OVR:	10322921(ND4)

MBEZ:

7872551(ND4)

SSC:	808510(ND4)

CFR:	5326228(ND4)

CBAI:

5309941(ND4)

CDK:	5618958(ND4)

VPC:	809433(ND4)

BMUS:

807734(ND4)

LVE:	3802089(ND4)

OOR:	72909401(ND4)

LALB:

2658645(ND4)

DLE:	31413004(ND4)

PCAD:

809410(ND4)

ECB:	807852(ND4)

EPZ:	19019457(ND4)

EAI:	808055(ND4)

MYB:	20964701(ND4)

MYD:	22203926(ND4)

MMYO:

26889508(ND4)

MLF:	27214799(ND4)

DRO:	17046627(ND4)

AJM:	808341(ND4)

PDIC:

74550833(ND4)

HAI:	13539874(ND4)

PALE:

17963503(ND4)

MJV:	24019678(ND4)

TOD:	38289037(D9W85_mgp04)

LAV:	808784(ND4)

ETF:	802333(ND4)

DNM:	808133(ND4)

MDO:	3074656(ND4)

GAS:	63652817(ND4)

SHR:	13826443(ND4)

AFZ:	65342061(ND4)

PCW:	4108305(ND4)

TVP:	803531(ND4)

OAA:	808699(ND4)

GGA:	39116916(ND4)

PCOC:

10609904(ND4)

MGP:	5848007(ND4)

CJO:	804664(ND4)

LMUT:

31079447(ND4)

NMEL:

32282771(ND4)

APLA:

5405811(ND4)

ACYG:

18887307(ND4)

CATA:

7996706(ND4)

AFUL:

19909404(ND4)

TGU:	3950799(ND4)

LSR:	26897981(ND4)

SCAN:

37275781(ND4)

PMOA:

20355705(ND4)

OTC:	22548467(ND4)

PRUF:

17674387(ND4)

MATE:

60253636(ND4)

MAEN:

13825797(ND4)

FAB:	16027884(ND4)

PHI:	9481001(ND4)

PMAJ:

39089565(ND4)

CCW:	71712355(ND4)

ACOE:

60235428(ND4)

MMEA:

20357141(ND4)

SATI:

5846193(ND4)

FPG:	808597(ND4)

FCH:	23808606(ND4)

FRS:	26890153(ND4)

AGEN:

7256442(ND4)

EGZ:	18985256(ND4)

NNI:	4108701(ND4)

PADL:

26737709(ND4)

GSTE:

3416056(ND4)

CBOY:

809236(ND4)

CLV:	8890004(ND4)

GAME:

14840900(ND4)

RTD:	84348665(ND4)

AROW:

62676615(ND4)

NPD:	62676482(ND4)

DNE:	803260(ND4)

ASN:	806135(ND4)

AMJ:	808235(ND4)

CPOO:

4108093(ND4)

GGN:	4178391(ND4)

PSS:	2943120(ND4)

CIZ:	25099110(ND4)

CMY:	808653(ND4)

CCAY:

11747783(ND4)

CPIC:

18983003(ND4)

CABI:

60253662(ND4)

ACS:	6385974(ND4)

PVT:	3338347(ND4)

PBI:	YP_008083608

PMUR:

15822639(ND4)

PMUA:

7056469(ND4)

ZVI:	24146083(YC27_gp04)

GJA:	26044410(ND4)

EMC:	30861800(ND4)

XLA:	2642077(ND4)

XTR:	3283501(ND4)

NPR:	24020220(ND4)

ACAT:

17427717(ND4)

PADS:

41662603(ND4)

BGAR:

4356053(ND4)

MUO:	18490113(ND4)

GSH:	14469878(ND4)

DRE:	140534(ND4)

SRX:	24419164(ND4)

SANH:

24419966(ND4)

SGH:	8382171(ND4)

CCAR:

807770(ND4)

CGIB:

9222073(ND4)

PTET:

5787376(ND4)

LROH:

12079585(ND4)

OMC:	18668126(ND4)

PPRM:

26048325(ND4)

RKG:	130077645 130077647 130077649 130077651

MAMB:

5912296(ND4)

CIDE:

5857717(ND4)

CERY:

20160554(ND4)

MASI:

3131135(ND4)

TROS:

14048444(ND4)

TDW:	36952172(ND4)

MANU:

6879718(ND4)

PDAB:

18668405(ND4)

IPU:	804882(ND4)

IFU:	26118468(ND4)

PHYP:

16216576(ND4)

SMEO:

10079906(ND4)

TVC:	10079795(ND4) 132858792

CGAR:

25103318(ND4)

TRN:	134307548 134307554 134307561 134307584 134307593

CHAR:

5228441(ND4)

ASAD:

9978354(ND4)

TRU:	805214(ND4)

TFS:	19524540(ND4)

TNG:	BAE79226(ND4)

LCO:	7095390(ND4)

NCC:	10752031(ND4)

PGEO:

67284268(ND4)

EMAC:

30862049(ND4)

ELY:	7095525(ND4)

EFO:	14412336(ND4)

PLEP:

4363291(ND4)

SLUC:

23629811(ND4)

ESP:	40141415(ND4)

PFLV:

14048228(ND4)

GAT:

120813664

AFB:	13230437(ND4)

PSWI:

72130128(ND4)

MSAM:

4100034(ND4)

SCHU:

10965119(ND4)

EARM:

8382049(ND4)

CUD:	8774893(ND4)

LMIX:

132960636

MZE:

26037625

ONL:	8677320(ND4)

OAU:	8745948(ND4)

OLA:	805433(ND4)

OML:	13540116(ND4)

CSAI:

804084(ND4)

XMA:	6986213(ND4)

XCO:	26048173(ND4)

XHE:	8302515(ND4)

PRET:

19590706(ND4)

GAF:	805445(ND4)

CVG:	26048363(ND4)

CTUL:

26129133(ND4)

NFU:	7256394(ND4)

KMR:	804462(ND4)

AOCE:

4850665(ND4)

CSEM:

7996488(ND4)

POV:	808842(ND4)

SSEN:

4266848(ND4)

HHIP:

5405704(ND4)

HSP:	5405781(ND4)

SMAU:

8382081(ND4)

LCF:	3703596(ND4)

SDU:	11669696(ND4)

XGL:	7871604(ND4)

HCQ:	14658019(ND4)

SBIA:

35996568(ND4)

PTAO:

74193762(ND4)

BPEC:

YP_004935140.1

MALB:

803933(ND4)

BSPL:

23631940(ND4)

SJO:	8703823(ND4)

GMH:	808450(ND4)

SASA:

808305(ND4)

STRU:

19099184(ND4)

OTW:	KEF73_p04(ND4)

OMY:	807978(ND4)

OGO:	6383205(ND4)

ONE:	4555706(ND4)

OKI:	4955085(ND4)

OKE:	12486869(ND4)

OMM:	4657592(ND4)

SALP:

808551(ND4)

SNH:	35115204(ND4)

CCLU:

14842640(ND4)

ELS:	806645(ND4)

SFM:	3416100(ND4)

AANG:

3190262(ND4)

LOC:	807201(ND4)

PSPA:

805402(ND4)

ARUT:

17097827(ND4)

LCM:	808092(ND4)

CMK:	9385353(ND4)

RTP:	18267185(ND4)

CPLA:

7768751(ND4)

SCAU:

808293(ND4)

LERI:

11452187(ND4)

HAKA:

15333374(ND4)

PMRN:

807809(ND4)

LRJ:	9385092(ND4)

BFO:	808733(ND4)

BBEL:

806237(ND4)

SCLV:

36165653(ND4)

SPU:	2652724(ND4)

LVG:	36941415(ND4)

AJJ:	139965207 7802874(ND4)

APLC:

3907682(ND4)

AAMU:

3239013(ND4)

SKO:	3703608(ND4)

DME:	Dmel_CG34085(ND4)

DSE:	2760944(ND4)

DSI:

DYA:

CCAT:

808519(ND4)

BOD:	2717258(ND4)

BDR:	125780289 4657570(ND4)

AOQ:	79023093(ND4)

MDE:	20358588(ND4)

SCAC:

131996921

LSQ:	5469273(ND4)

ECOE:

35199159(ND4)

HIS:	33350939(ND4)

AGA:	85940929(ND4)

ACOZ:

26121331(ND4)

AARA:

26121217(ND4)

AMER:

26121521(ND4)

AMAP:

73620785(ND4)

AFUN:

76054181(ND4)

AMOU:

73620861(ND4)

AMRS:

73620823(ND4)

ANIL:

73620937(ND4)

ADAR:

73621013(ND4)

AAG:	33307568(ND4)

AALB:

3260131(ND4)

CQU:

CPII:

10200335(ND4)

CBRI:

87696346(ND4)

PPAP:

129809030 129809036 26044659(ND4)

ACER:

9385645(ND4)

ALAB:

34829168(ND4)

AFLR:

15822490(ND4)

BAFF:

126928125

CCAL:

113464313

SOC:	9977796(ND4)

TCZ:

108759596

VEM:	27912166(ND4)

HST:

112589758

CFO:

109610425

FEX:

115244948

LHU:	136997505 137001860 42265453(ND4)

TPRE:

111693312

LBD:

127290667

AGIF:

63649835(ND4)

CCIN:

112495303 7872299(ND4)

AROA:

112694905

TCA:	803822(ND4)

TMOL:

138140756

EFOR:

136349773

SOY:	28481412(ND4)

AGRG:

126750050

ATD:	34926379(ND4)

AGB:	4171604(ND4)

APLN:

28479651(ND4)

OTU:

111425805

BMOR:

809259(ND4)

BMAN:

804654(ND4)

MSEX:

5848756(ND4)

DPL:	AGL76306(ND4)

BANY:

128199785 128199786

PMAC:

106711772 13080348(ND4)

PPOT:

106110401 20159554(ND4)

PXU:	106115606 26836892(ND4)

PRAP:

11030473(ND4)

PNAP:

60241354(ND4)

LSIN:

126978066

HAW:	9977719(ND4)

HZE:	71203143(ND4)

TNL:	113502836 113502921 44149119(ND4)

SLIU:

17427401(ND4)

ATRA:

26281603(ND4)

GMW:	26376099(ND4)

ECLR:

140757092

PXY:	20834453(ND4)

PGW:	73956689(ND4)

CSTB:

134752856

CFUM:

36490492(ND4)

CFEL:

113365378

API:	7055882(ND4)

DNX:	17428416(ND4)

AGS:	19909107(ND4)

BTAB:

3077228(ND4)

DCI:	113467914 27914379(ND4)

CLEC:

27787576(ND4)

HHAL:

112211071 8457889(ND4)

NLU:	16216533(ND4)

LDA:	7996606(ND4)

HVI:	3332286(ND4)

MQU:	32891630(ND4)

FOC:	YP_006576367

TPAL:

38092101(ND4)

ZNE:	20004819(ND4)

PAME:

138707287

SGRE:

73491810(ND4)

DPX:	AAD33238(ND4)

DMK:	24147216(ND4)

AFRA:

807792(ND4)

PVM:	138859543 138859544 138859562 5333213(ND4)

PJA:	3416049(ND4)

PCHN:

5333411(ND4)

PMOO:

808984(ND4)

HAME:

10743678(ND4)

PCLA:

11763606(ND4)

CQD:	17728537(ND4)

PTRU:

1482831(ND4)

SPRM:

7768776(ND4)

ESN:	3355542(ND4)

MNZ:	10200250(ND4)

MRJ:	3293146(ND4)

PORN:

10094403(ND4)

HAZT:

38169100(ND4)

OOT:	9481013(ND4)

TCF:	4788318(ND4)

DSV:	23630425(ND4)

DALB:

139054070

RSAN:

808367(ND4)

RMP:	18250943(ND4)

VDE:	806159(ND4)

TUT:	6164213(ND4)

DPTE:

7564653(ND4)

ABRU:

19591987(ND4)

SDM:

118205706

LPOL:

803783(ND4)

CEL:	KEF34_p05(ND4)

CBR:

NAI:	804823(ND4)

BMY:	KEF88_p11(ND4)

LOA:

TSP:

HRO:	HELRODRAFT_184509

PCAN:

19909186(ND4)

LSAX:

28261504(ND4)

BARL:

143298659 17960493(ND4)

BGT:	2746311(ND4)

HRF:	35985154(ND4)

HRJ:	2846693(ND4)

CRG:	808833(ND4)

CANU:

7865912(ND4)

MYI:	4910442(ND4)

YBA:

132547001

MMER:

55289776(ND4)

RPHI:

29141302(ND4)

MAEA:

20159499(ND4)

OBI:	27205965(ND4)

OSN:	62676642(ND4)

LJP:	135481465 79134692(ND4)

LAK:	C2G87_mgp03(ND4)

SMM:

120693831 120694244 120694315

SHX:	4097446(ND4)

EGL:	41697831(nad4)

ATEN:

41854782(ND4)

DGT:	8656274(ND4)

HMG:	6904238(ND4)

RES:	33911778(ND4)

TAD:	TradoM_p14(ND4)

AQU:	4794343(ND4)

ATH:	DA397_mgp23(nad4)

CRB:	40490685(nad4)

EUS:	EUTSA_v10015949mg

BRP:	56141060(nad4)

BNA:	4237889(nad4)

RSZ:	13630146(nad4)

CPAP:

7441409(nad4)

CIT:	36487008(nad4)

GRA:	27429575(nad4) 27429623(nad4)

GHI:	24679536(nad4)

GAB:	128284183 33134356(nad4) 33134387(nad4)

HSYR:

120185221 120202667

EGR:	38466573(nad4)

GMX:	15308566(nad4)

GSJ:	38334444(nad4)

PVU:	42317460(nad4)

VAR:	15382812(nad4)

MTR:	26974347(nad4)

TPRA:

55290714(nad4)

VVO:

131637807

ADU:

127744524

AHF:	112754387 114927292

PCIN:

129294853

PDUL:

117612509

MDM:	13630194(nad4)

MSYL:

73938901(nad4)

ZJU:	27215259(nad4)

MNT:	39338992(nad4)

CSAV:

27215456(nad4)

CSV:	11123909(nad4)

RCU:	10221437(nad4)

HBR:

110639967

MESC:

42317501(nad4)

POP:

127905548

QSU:

112005410

QLO:

115986322

VVI:	7498663(nad4)

SLY:	34678311(nad4)

SPEN:

114074671 34926019(nad4)

CANN:

124897057 19988996(nad4)

NTA:	3205277(nad4)

NSY:	27214860(nad4)

NAU:	35198946(nad4)

INI:	29082077(nad4)

SMIL:

18126360(nad4)

ECAD:

122584408

LSV:	40498732(nad4)

DCR:	135150748 88614167(nad4)

AGRV:

141680135 68216241(nad4) 68216338(nad4)

CSIN:

40867558(nad4)

AEW:	88577549(nad4)

BVG:	809503(nad4) 809588(orf288)

SOE:	33876608(nad4)

CQI:	39331965(nad4)

ATRI:

130827000 130827078

SLAF:

9725747(nad4)

NNU:	28482703(nad4)

MING:

122081646

TSS:	122647047 122647730

PSOM:

113349223

OSA:	6450121(nad4)

DOSA:

nad4

TDC:	119272111 119283638 119295825 119299392 119350376 119350378

TAES:

123129600 34688790(nad4)

TUA:	125532020 125532263 125532430

SBI:	4306054(nad4)

PVIR:

PDA:	11542563(nad4)

ZOF:	122015203 122037646

NCOL:

36487341(nad4)

CJF:	131873007 131873322 131873464

PPP:	3989057(nad4)

CRE:	ChrepMp02(nad4)

CSL:	CospCoM_p06(nad4)

CVR:	OJ20_p02(nad4)

APRO:

ChprMp028(nad4)

OTA:	OstapMp35(nad4)

BPG:	BathyMg00070(nad4)

MIS:	MicpuN_mit24(nad4)

GSL:	JL72_p14(nad4)

CCP:	ChcroMp17(nad4)

DHA:

PGU:	PGUG_05918

LBG:	89432277(nad4)

CAL:	CaalfMp14(NAD4)

CLUS:

16792607(nad4)

YLI:	802604(nd4)

NCR:

NCU16020

PAN:	PoanfMp46(nad4)

CTHR:

CTHT_m000480

SSCK:

SPSK_11052

FGR:	GizefMp12(nad4)

PTKZ:

MRV25_mgp06(nad4)

VAL:	VDBG_17003 VDBG_17016

CLUP:

AYB75_mgp15(nad4)

SSL:	SS1G_20032

ANI:	ANID_20008

ANG:	Asnifp05(nad4)

ALUC:

EJ508_mgp13(nad4)

CPW:	90965854(nad4)

PNO:

SNOGp07

BZE:	COCCADRAFT_112453

BOR:	COCMIDRAFT_111274

KSH:	87952621(IL334_000490)

MRT:	D9L16_mgp05(nad4)

PSTR:

EFH26_mgp03(nad4)

DDI:	DidioMp02(nad4)

DFA:	Difao_mp01(nad4)

TET:	TepyoMp44(nad4)

PSOJ:

PhsooMp20(nad4)

BLAC:

38665162(nad4)

Reference

PMID:1323207

Authors

Lertrit P, Noer AS, Jean-Francois MJ, Kapsa R, Dennett X, Thyagarajan D, Lethlean K, Byrne E, Marzuki S

Title

A new disease-related mutation for mitochondrial encephalopathy lactic acidosis and strokelike episodes (MELAS) syndrome affects the ND4 subunit of the respiratory complex I.

Journal

Am J Hum Genet 51:457-68 (1992)

Sequence

[hsa:4538]

LinkDB

ORTHOLOGY: K03882

Entry

K03882                      KO

Symbol

ND4L

Name

NADH-ubiquinone oxidoreductase chain 4L [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00068

Leber hereditary optic atrophy

H00473

Mitochondrial complex I deficiency

H01355

Kearns-Sayre syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
  09159 Environmental adaptation
   04714 Thermogenesis
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
   05012 Parkinson disease
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
   05014 Amyotrophic lateral sclerosis
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
   05016 Huntington disease
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
   05020 Prion disease
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
   05022 Pathways of neurodegeneration - multiple diseases
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L

Other DBs

GO:

TC:

Genes

HSA:	4539(ND4L)

PTR:	807868(ND4L)

PPS:	807881(ND4L)

GGO:	6742685(ND4L)

PON:	808477(ND4L)

PPYG:

807905(ND4L)

NLE:	16545235(ND4L)

SSYN:

9072797(ND4L)

MCC:	2846621(ND4L)

MCF:	7857745(ND4L)

CSAB:

4097496(ND4L)

CATY:

26408654(ND4L)

PANU:

14444637(ND4L)

TGE:	14216789(ND4L)

RRO:	4171542(ND4L)

RBB:	10549375(ND4L)

TFN:	18985080(ND4L)

CJC:	22203908(ND4L)

SBQ:	13228919(ND4L)

ANAN:

13230274(ND4L)

CSYR:

7944467(ND4L)

MMUR:

26823982(ND4L)

LCAT:

68929187(ND4L)

PCOQ:

6458117(ND4L)

MMU:	17720(ND4L)

MCAL:

20832250(ND4L)

MPAH:

36165335(ND4L)

RNO:	26200(ND4L)

MCOC:

34683010(ND4L)

MUN:	18129812(ND4L)

CGE:	3979178(ND4L)

MAUA:

8457931(ND4L)

PROB:

30213876(BOP69_gp05)

PLEU:

36275557(ND4L)

NGI:	15088431(ND4L)

HGL:	10201217(ND4L)

CPOC:

808638(ND4L)

CCAN:

31082914(ND4L)

ITI:	24576595(ND4L)

OCU:	808222(ND4L)

OPI:	2717283(ND4L)

GVR:	804972(ND4L)

CFA:	804482(ND4L)

VVP:	4355761(ND4L)

VLG:	23629754(ND4L)

NPO:	8690248(ND4L)

AML:	5179735(ND4L)

UMR:	804868(ND4L)

UAR:	804842(ND4L)

LLV:	71922423(ND4L)

MNP:	20466146(ND4L)

NVS:	14841847(ND4L)

EJU:	805012(ND4L)

ZCA:	4355798(ND4L)

MLX:	4355874(ND4L)

LWW:	4355836(ND4L)

FCA:	807937(ND4L)

PYU:	26129877(ND4L)

PCOO:

11473386(ND4L)

PBG:	26129497(ND4L)

PVIV:

26129649(ND4L)

LGF:	26130219(ND4L)

AJU:	2654023(ND4L)

PPAD:

6262378(ND4L)

PUC:	6262406(ND4L)

PLEZ:

26129535(ND4L)

HHV:	14842163(ND4L)

BTA:	3283885(ND4L)

BOM:	22161774(ND4L)

BIU:	2885969(ND4L)

BJV:	7901815(ND4L)

BBUB:

56055859(ND4L)

CHX:	1485864(ND4L)

OAS:	808256(ND4L)

OCAN:

11030004(ND4L)

BTAX:

8250968(ND4L)

CSUM:

14841693(ND4L)

ODA:	11452046(ND4L)

CCAD:

59433142(ND4L)

MREE:

805178(ND4L)

OVR:	10322920(ND4L)

MBEZ:

7872550(ND4L)

SSC:	808509(ND4L)

CFR:	5326227(ND4L)

CBAI:

5309936(ND4L)

CDK:	5618955(ND4L)

VPC:	809422(ND4L)

BMUS:

807737(ND4L)

LVE:	3802088(ND4L)

OOR:	72909423(ND4L)

LALB:

2658646(ND4L)

DLE:	31412990(ND4L)

PCAD:

809413(ND4L)

ECB:	807851(ND4L)

EPZ:	19019455(ND4L)

EAI:	808056(ND4L)

MYB:	20964700(ND4L)

MYD:	22203922(ND4L)

MMYO:

26889530(ND4L)

MLF:	27214822(ND4L)

DRO:	17046631(ND4L)

AJM:	808338(ND4L)

PDIC:

74550856(ND4L)

HAI:	13539873(ND4L)

PALE:

17963502(ND4L)

MJV:	24019677(ND4L)

TOD:	38289023(D9W85_mgp05)

LAV:	808785(ND4L)

ETF:	802334(ND4L)

DNM:	808134(ND4L)

MDO:	3074657(ND4L)

GAS:	63652840(ND4L)

SHR:	13826441(ND4L)

AFZ:	65342084(ND4L)

PCW:	4108306(ND4L)

TVP:	803528(ND4L)

OAA:	808698(ND4L)

GGA:	39116939(ND4L)

PCOC:

10609903(ND4L)

MGP:	5848001(ND4L)

CJO:	804662(ND4L)

LMUT:

31079470(ND4L)

NMEL:

32282794(ND4L)

APLA:

5405815(ND4L)

ACYG:

18887306(ND4L)

CATA:

7996705(ND4L)

AFUL:

19909403(ND4L)

TGU:	3950798(ND4L)

LSR:	26897972(ND4L)

SCAN:

37275784(ND4L)

PMOA:

20355704(ND4L)

OTC:	22548466(ND4L)

PRUF:

17674382(ND4L)

FAB:	16027883(ND4L)

PHI:	9481000(ND4L)

PMAJ:

39089588(ND4L)

CCW:	71712354(ND4L)

ACOE:

60235427(ND4L)

MMEA:

20357140(ND4L)

SATI:

5846184(ND4L)

FPG:	808595(ND4L)

FCH:	23808605(ND4L)

AGEN:

7256440(ND4L)

EGZ:	18985255(ND4L)

NNI:	4108702(ND4L)

PADL:

26737708(ND4L)

GSTE:

3416055(ND4L)

CBOY:

809237(ND4L)

CLV:	8890002(ND4L)

GAME:

14840899(ND4L)

RTD:	84348664(ND4L)

AROW:

62676583(ND4L)

NPD:	62676481(ND4L)

DNE:	803259(ND4L)

ASN:	806130(ND4L)

AMJ:	808238(ND4L)

CPOO:

4108094(ND4L)

GGN:	4178392(ND4L)

PSS:	2943116(ND4L)

CIZ:	25099109(ND4L)

CMY:	808643(ND4L)

CCAY:

11747793(ND4L)

CPIC:

18983002(ND4L)

CABI:

60253696(ND4L)

ACS:	6385973(ND4L)

PVT:	3338358(ND4L)

PBI:	YP_008083607

PMUR:

15822638(ND4L)

PMUA:

7056468(ND4L)

ZVI:	24146105(YC27_gp05)

GJA:	26044432(ND4L)

EMC:	30861822(ND4L)

XLA:	2642076(ND4L)

XTR:	3283500(ND4L)

NPR:	24020218(ND4L)

ACAT:

17427716(ND4L)

PADS:

41662625(ND4L)

BGAR:

4356052(ND4L)

MUO:	18490102(ND4L)

GSH:	14469877(ND4L)

DRE:	140538(ND4L)

SRX:	24419162(ND4L)

SANH:

24419950(ND4L)

SGH:	8382170(ND4L)

CCAR:

807768(ND4L)

CGIB:

9222072(ND4L)

PTET:

5787382(ND4L)

LROH:

12079588(ND4L)

OMC:	18668125(ND4L)

PPRM:

26048347(ND4L)

MAMB:

5912297(ND4L)

CIDE:

5857714(ND4L)

CERY:

20160553(ND4L)

MASI:

3131143(ND4L)

TROS:

14048443(ND4L)

TDW:	36952195(ND4L)

MANU:

6879717(ND4L)

PDAB:

18668404(ND4L)

IPU:	804881(ND4L)

IFU:	26118490(ND4L)

PHYP:

16216575(ND4L)

SMEO:

10079905(ND4L)

TVC:	10079794(ND4L)

CGAR:

25103341(ND4L)

CHAR:

5228437(ND4L)

ASAD:

9978353(ND4L)

TRU:	805213(ND4L)

TFS:	19524539(ND4L)

TNG:	BAE79225(ND4L)

LCO:	7095389(ND4L)

NCC:	10752030(ND4L)

PGEO:

67284267(ND4L)

EMAC:

30862048(ND4L)

ELY:	7095524(ND4L)

EFO:	14412335(ND4L)

PLEP:

4363290(ND4L)

SLUC:

23629810(ND4L)

ESP:	40141439(ND4L)

PFLV:

14048227(ND4L)

AFB:	13230436(ND4L)

PSWI:

72130144(ND4L)

MSAM:

4100033(ND4L)

SCHU:

10965117(ND4L)

EARM:

8382046(ND4L)

CUD:	8774887(ND4L)

MZE:

26037647

ONL:	8677319(ND4L)

OAU:	8745947(ND4L)

OLA:	805434(ND4L)

OML:	13540115(ND4L)

CSAI:

804086(ND4L)

XMA:	6986211(ND4L)

XCO:	26048195(ND4L)

XHE:	8302514(ND4L)

PRET:

19590707(ND4L)

GAF:	805452(ND4L)

CVG:	26048385(ND4L)

CTUL:

26129155(ND4L)

NFU:	7256392(ND4L)

KMR:	804469(ND4L)

AOCE:

4850673(ND4L)

CSEM:

7996487(ND4L)

POV:	808843(ND4L)

SSEN:

4266849(ND4L)

HHIP:

5405716(ND4L)

HSP:	5405789(ND4L)

SMAU:

8382080(ND4L)

LCF:	3703595(ND4L)

SDU:	11669685(ND4L)

XGL:	7871602(ND4L)

HCQ:	14658018(ND4L)

SBIA:

35996591(ND4L)

PTAO:

74193761(ND4L)

BPEC:

YP_004935139.1

MALB:

803936(ND4L)

BSPL:

23631938(ND4L)

SJO:	8703821(ND4L)

GMH:	808456(ND4L)

SASA:

808312(ND4L)

STRU:

19099183(ND4L)

OTW:	KEF73_p05(ND4L)

OMY:	807974(ND4L)

OGO:	6383210(ND4L)

ONE:	4555717(ND4L)

OKI:	4955081(ND4L)

OKE:	12486858(ND4L)

OMM:	4657595(ND4L)

SALP:

808550(ND4L)

SNH:	35115224(ND4L)

CCLU:

14842639(ND4L)

ELS:	806657(ND4L)

SFM:	3416099(ND4L)

AANG:

3190259(ND4L)

LOC:	807202(ND4L)

PSPA:

805413(ND4L)

ARUT:

17097826(ND4L)

LCM:	808091(ND4L)

CMK:	9385352(ND4L)

RTP:	18267184(ND4L)

CPLA:

7768750(ND4L)

SCAU:

808298(ND4L)

LERI:

11452186(ND4L)

HAKA:

15333373(ND4L)

PMRN:

807811(ND4L)

LRJ:	9385090(ND4L)

BFO:	808732(ND4L)

BBEL:

806239(ND4L)

SCLV:

36165628(ND4L)

SPU:	2652719(ND4L)

LVG:	36941439(ND4L)

AJJ:	7802868(ND4L)

APLC:

3907683(ND4L)

AAMU:

3239018(ND4L)

SKO:	3703607(ND4L)

DME:	Dmel_CG34086(ND4L)

DSE:	2760942(ND4L)

DSI:

DYA:

CCAT:

808515(ND4L)

BOD:	2717257(ND4L)

BDR:	4657578(ND4L)

AOQ:	79023094(ND4L)

MDE:	20358593(ND4L)

LSQ:	5469263(ND4L)

ECOE:

35199142(ND4L)

HIS:	33350912(ND4L)

AGA:	85940908(ND4L)

ACOZ:

26121304(ND4L)

AARA:

26121190(ND4L)

AMER:

26121494(ND4L)

AMAP:

73620786(ND4L)

AFUN:

76054160(ND4L)

AMOU:

73620862(ND4L)

AMRS:

73620824(ND4L)

ANIL:

73620938(ND4L)

ADAR:

73621014(ND4L)

AAG:	33307548(ND4L)

AALB:

3260127(ND4L)

CQU:	CpipJ_CPIJ018968 ND4L

CPII:

10200336(ND4L)

CBRI:

87696328(ND4L)

PPAP:

26044638(ND4L)

ACER:

9385646(ND4L)

ALAB:

34829148(ND4L)

AFLR:

15822491(ND4L)

SOC:	9977797(ND4L)

VEM:	27912176(ND4L)

LHU:	42265431(ND4L)

VVE:	33194918(ND4L)

AGIF:

63649836(ND4L)

CCIN:

7872300(ND4L)

TCA:	803819(ND4L)

SOY:	28481391(ND4L)

ATD:	34926380(ND4L)

AGB:	4171592(ND4L)

APLN:

28479652(ND4L)

BMOR:

809260(ND4L)

BMAN:

804646(ND4L)

MSEX:

5848757(ND4L)

DPL:	AGL76307(ND4L)

PMAC:

13080349(ND4L)

PPOT:

20159556(ND4L)

PXU:	26836883(ND4L)

PRAP:

11030476(ND4L)

PNAP:

60241333(ND4L)

HAW:	9977720(ND4L)

HZE:	71203144(ND4L)

TNL:	44149130(ND4L)

SLIU:

17427402(ND4L)

ATRA:

26281575(ND4L)

GMW:	26376078(ND4L)

PXY:	20834454(ND4L)

PGW:	73956667(ND4L)

CFUM:

36490470(ND4L)

API:	7055883(ND4L)

DNX:	17428417(ND4L)

AGS:	19909108(ND4L)

BTAB:

3077231(ND4L)

DCI:	27914393(ND4L)

CLEC:

27787583(ND4L)

HHAL:

8457890(ND4L)

NLU:	16216534(ND4L)

LDA:	7996607(ND4L)

HVI:	3332275(ND4L)

MQU:	32891609(ND4L)

FOC:	YP_006576368

TPAL:

38092102(ND4L)

ZNE:	20004820(ND4L)

SGRE:

73491811(ND4L)

DPX:	AAD33239(ND4L)

DMK:	24147192(ND4L)

AFRA:

807794(ND4L)

PVM:	5333212(ND4L)

PJA:	3416050(ND4L)

PCHN:

5333405(ND4L)

PMOO:

808985(ND4L)

HAME:

10743679(ND4L)

PCLA:

11763605(ND4L)

CQD:	17728538(ND4L)

PTRU:

1482832(ND4L)

SPRM:

7768777(ND4L)

ESN:	3355543(ND4L)

MNZ:	10200251(ND4L)

MRJ:	3293144(ND4L)

PORN:

10094404(ND4L)

HAZT:

38169117(ND4L)

OOT:	9481014(ND4L)

DSV:	23630428(ND4L)

RSAN:

808363(ND4L)

RMP:	18250944(ND4L)

VDE:	806158(ND4L)

TUT:	6164215(ND4L)

DPTE:

7564652(ND4L)

ABRU:

19591988(ND4L)

LPOL:

803779(ND4L)

CEL:	KEF34_p11(ND4L)

CBR:

NAI:	804822(ND4L)

LOA:

TSP:

HRO:	HELRODRAFT_113318 HELRODRAFT_85898 HELRODRAFT_92830

PCAN:

19909185(ND4L)

LSAX:

28261525(ND4L)

BARL:

17960492(ND4L)

BGT:	2746318(ND4L)

HRF:	35985155(ND4L)

HRJ:	2846701(ND4L)

MYI:	4910440(ND4L)

MMER:

55289788(ND4L)

MAEA:

20159507(ND4L)

OBI:	27205966(ND4L)

OSN:	62676643(ND4L)

LAK:	C2G87_mgp11(ND4L)

ATEN:

41854787(ND4L)

ADF:	17674595(ND4L)

PDAM:

5580399(ND4L)

SPIS:

6798786(ND4L)

HMG:	6904239(ND4L)

RES:	33911768(ND4L)

TAD:	TradoM_p18(ND4L)

AQU:	4794369(ND4L)

ATH:	DA397_mgp04(nad4L)

CRB:	40490663(nad4L)

EUS:	EUTSA_v10023053mg

BRP:	56141017(nad4L)

BNA:	4237890(nad4L)

RSZ:	13630126(nad4L)

CPAP:

7441463(nad4L)

CIT:	36486997(nad4L)

GRA:	27429606(nad4L)

GHI:	24679522(nad4L)

GAB:	33134397(nad4L)

EGR:	38466568(nad4L)

GMX:	15308568(nad4L-1) 15308603(nad4L-2)

PVU:	42317452(nad4L)

MTR:	26974330(nad4L)

TPRA:

55290708(nad4L)

MDM:	13630195(nad4L)

MSYL:

73938920(nad4L)

ZJU:	27215237(nad4L)

MNT:	39339012(nad4L)

CSAV:

27215453(nad4L)

CSV:	11123905(nad4L)

RCU:	10221406(nad4L)

MEAN:

126660888

MESC:

42317503(nad4L)

VVI:	7498582(nad4L)

SLY:	34678266(nad4L)

SPEN:

34925984(nad4L)

CANN:

19988966(nad4L)

NTA:	3205337(nad4L)

NSY:	27214845(nad4L)

NAU:	35198926(nad4L)

SMIL:

18126348(nad4L)

HAN:	18251003(nad4L)

LSV:	40498774(nad4L)

DCR:	88614207(nad4L)

AGRV:

68216277(nad4L)

CSIN:

40867546(nad4l)

AEW:	88577542(nad4L)

BVG:	809472(nad4L)

SOE:	33876595(nad4L)

CQI:	39331940(nad4L)

SLAF:

9725735(nad4L)

NNU:	28482648(nad4L)

OSA:	6450148(nad4L)

DOSA:

nad4L

TAES:

34688772(nad4L)

SBI:	4306018(nad4L)

PDA:	11542558(nad4L)

NCOL:

36487319(nad4L)

CJF:	131077510 131872581

SMO:	SELMODRAFT_138426

PPP:	3989058(nad4L)

CSL:	CospCoM_p25(nad4L)

CVR:	OJ20_p11(nad4L)

APRO:

ChprMp007(nad4L)

OTA:	OstapMp21 OstapMp43

BPG:	BathyMg00220(nad4L)

MIS:	MicpuN_mit48(nad4L)

CCP:	ChcroMp25(nad4L)

DHA:

LBG:	89432248(nad4L)

CAL:	CaalfMp12(NAD4L)

CLUS:

16792573(nad4L)

YLI:	802609(nd4L)

NCR:

NCU16008

PAN:	PoanfMp34(nad4L)

CTHR:

CTHT_m000360

SSCK:

SPSK_11050

FGR:	GizefMp07(nad4L)

CMT:

CCM_09676

PTKZ:

MRV25_mgp11(nad4L)

CLUP:

AYB75_mgp10(nad4L)

ANI:	ANID_20000

ANG:	Asnifp14(nad4L)

ALUC:

EJ508_mgp04(nad4L)

CPW:	90965896(nad4L)

PNO:	SNOGp11(nad4L)

BOR:	COCMIDRAFT_42581

LBC:	LACBIDRAFT_238848

ABP:	AGABI1DRAFT18188(AGABI1DRAFT_18188)

ABV:	AGABI2DRAFT75823(AGABI2DRAFT_75823)

MRT:	D9L16_mgp09(nad4L)

PSTR:

EFH26_mgp12(nad4L)

DDI:	DidioMp41(nad4L)

MTEN:

GWK48_09995

Reference

PMID:1757091

Authors

Marzuki S, Noer AS, Lertrit P, Thyagarajan D, Kapsa R, Utthanaphol P, Byrne E

Title

Normal variants of human mitochondrial DNA and translation products: the building of a reference data base.

Journal

Hum Genet 88:139-45 (1991)
DOI:10.1007/BF00206061

Sequence

[hsa:4539]

LinkDB

ORTHOLOGY: K03883

Entry

K03883                      KO

Symbol

ND5

Name

NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00068

Leber hereditary optic atrophy

H00473

Mitochondrial complex I deficiency

H01347

MELAS syndrome

H01355

Kearns-Sayre syndrome

H01356

Myoclonic Epilepsy and Ragged-Red Fiber Disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
  09159 Environmental adaptation
   04714 Thermogenesis
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
   05012 Parkinson disease
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
   05014 Amyotrophic lateral sclerosis
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
   05016 Huntington disease
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
   05020 Prion disease
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
   05022 Pathways of neurodegeneration - multiple diseases
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03883  ND5; NADH-ubiquinone oxidoreductase chain 5
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03883  ND5; NADH-ubiquinone oxidoreductase chain 5

Other DBs

GO:

TC:

Genes

HSA:

4540(ND5)

PTR:	807860(ND5)

PPS:	807878(ND5)

GGO:	6742681(ND5)

PON:	808484(ND5)

PPYG:

807906(ND5)

NLE:	16545233(ND5)

SSYN:

9072798(ND5)

MCC:	2846631(ND5)

MCF:	7857747(ND5)

MTHB:

126947324

CSAB:

4097498(ND5)

CATY:

26408642(ND5)

PANU:

14444639(ND5)

TGE:	14216791(ND5)

RRO:	4171544(ND5)

RBB:	10549377(ND5)

TFN:	18985082(ND5)

CJC:	22203910(ND5)

SBQ:	13228907(ND5)

ANAN:

13230276(ND5)

CSYR:

7944472(ND5)

MMUR:

26823987(ND5)

LCAT:

68929190(ND5)

PCOQ:

6458126(ND5)

MMU:	17721(ND5)

MCAL:

20832252(ND5)

MPAH:

36165330(ND5)

RNO:	26202(ND5)

MCOC:

34683015(ND5)

MUN:	18129814(ND5)

CGE:	3979180(ND5)

MAUA:

8457933(ND5)

PROB:

30213879(BOP69_gp03)

PLEU:

36275560(ND5)

PMAV:

39105353(ND5)

NGI:	15088433(ND5)

HGL:	10201218(ND5)

CPOC:

808633(ND5)

CCAN:

31082919(ND5)

ITI:	24576598(ND5)

OCU:	808224(ND5)

OPI:	2717284(ND5)

GVR:	804980(ND5)

CFA:	804484(ND5)

VVP:	4355762(ND5)

VLG:	23629756(ND5)

NPO:	8690250(ND5)

AML:	5179734(ND5)

UMR:	804873(ND5)

UAR:	804837(ND5)

LLV:	71922428(ND5)

MNP:	20466148(ND5)

MLK:

131838643

NVS:	14841849(ND5)

EJU:	805020(ND5)

ZCA:	4355799(ND5)

MLX:	4355875(ND5)

LWW:	4355837(ND5)

FCA:	807929(ND5)

PYU:	26129880(ND5)

PCOO:

11473374(ND5)

PBG:	26129500(ND5)

PVIV:

26129652(ND5)

LGF:	26130222(ND5)

AJU:	2654012(ND5)

PPAD:

6262381(ND5)

PUC:	6262411(ND5)

PLEZ:

26129538(ND5)

HHV:	14842165(ND5)

BTA:	3283887(ND5)

BOM:	22161776(ND5)

BIU:	2885979(ND5)

BJV:	7901817(ND5)

BBUB:

56055862(ND5)

CHX:	1485866(ND5)

OAS:	808258(ND5)

OCAN:

11030006(ND5)

BTAX:

8250970(ND5)

CSUM:

14841695(ND5)

ODA:	11452048(ND5)

CCAD:

59433145(ND5)

MREE:

805180(ND5)

OVR:	10322922(ND5)

MBEZ:

7872552(ND5)

SSC:	808511(ND5)

CFR:	5326229(ND5)

CBAI:

5309943(ND5)

CDK:	5618957(ND5)

VPC:	809432(ND5)

BMUS:

807739(ND5)

LVE:	3802090(ND5)

OOR:	72909426(ND5)

LALB:

2658626(ND5)

DLE:	31412993(ND5)

PCAD:

809415(ND5)

ECB:	807853(ND5)

EPZ:	19019456(ND5)

EAI:	808058(ND5)

MYB:	20964702(ND5)

MYD:	22203927(ND5)

MMYO:

26889533(ND5)

MLF:	27214825(ND5)

DRO:	17046641(ND5)

AJM:	808343(ND5)

PDIC:

74550859(ND5)

HAI:	13539875(ND5)

PALE:

17963507(ND5)

MJV:	24019679(ND5)

TOD:	38289026(D9W85_mgp03)

LAV:	808793(ND5)

ETF:	802335(ND5)

DNM:	808129(ND5)

MDO:	3074665(ND5)

GAS:	63652843(ND5)

SHR:	13826442(ND5)

AFZ:	65342087(ND5)

PCW:	4108300(ND5)

TVP:	803529(ND5)

OAA:	808701(ND5)

GGA:	39116942(ND5)

PCOC:

10609905(ND5)

MGP:	5848002(ND5)

CJO:	804665(ND5)

LMUT:

31079473(ND5)

NMEL:

32282797(ND5)

APLA:

5405820(ND5)

ACYG:

18887308(ND5)

CATA:

7996707(ND5)

AFUL:

19909405(ND5)

TGU:	3950800(ND5)

LSR:	26897975(ND5)

SCAN:

37275798(ND5)

PMOA:

20355706(ND5)

OTC:	22548468(ND5)

PRUF:

17674383(ND5)

FAB:	16027888(ND5)

PHI:	9481002(ND5)

PMAJ:

39089591(ND5)

CCW:	71712359(ND5)

ACOE:

60235432(ND5)

MMEA:

20357142(ND5)

SATI:

5846195(ND5)

FPG:	808594(ND5)

FCH:	23808607(ND5)

AGEN:

7256441(ND5)

EGZ:	18985257(ND5)

NNI:	4108703(ND5)

PADL:

26737701(ND5)

GSTE:

3416057(ND5)

CBOY:

809235(ND5)

CLV:	8890005(ND5)

RTD:	84348669(ND5)

AROW:

62676613(ND5)

NPD:	62676494(ND5)

DNE:	803261(ND5)

ASN:	806134(ND5)

AMJ:	808242(ND5)

CPOO:

4108082(ND5)

GGN:	4178393(ND5)

PSS:	2943121(ND5)

CIZ:	25099111(ND5)

CMY:	808654(ND5)

CCAY:

11747784(ND5)

CPIC:

18983004(ND5)

CABI:

60253691(ND5)

ACS:	6385976(ND5)

PVT:	3338363(ND5)

PBI:	YP_008083609

PMUR:

15822640(ND5)

APRI:

131189253

PMUA:

7056470(ND5)

ZVI:	24146108(YC27_gp03)

GJA:	26044435(ND5)

EMC:	30861825(ND5)

XLA:	2642078(ND5)

XTR:	3283502(ND5)

NPR:	24020221(ND5)

ACAT:

17427718(ND5)

PADS:

41662641(ND5)

BGAR:

4356054(ND5)

MUO:	18490117(ND5)

GSH:	14469879(ND5)

DRE:	140535(ND5)

SRX:	24419157(ND5)

SANH:

24419962(ND5)

SGH:	8382172(ND5)

CCAR:

807769(ND5)

CGIB:

9222074(ND5)

PTET:

5787375(ND5)

LROH:

12079586(ND5)

OMC:	18668127(ND5)

PPRM:

26048350(ND5)

RKG:	130077644 130077646 130077648 130077650

MAMB:

5912291(ND5)

CIDE:

5857716(ND5)

CERY:

20160555(ND5)

MASI:

3131132(ND5)

TROS:

130568784 14048445(ND5)

TDW:	36952198(ND5)

MANU:

6879719(ND5)

PDAB:

18668406(ND5)

IPU:	804879(ND5)

IFU:	26118493(ND5)

PHYP:

16216579(ND5)

SMEO:

10079907(ND5)

TVC:	10079796(ND5) 132858791

CGAR:

25103344(ND5)

TRN:	134307547 134307560 134307583 134307592

CHAR:

5228445(ND5)

ASAD:

9978355(ND5)

TRU:	805223(ND5)

TFS:	19524541(ND5)

TNG:	BAE79227(ND5)

LCO:	7095391(ND5)

NCC:	10752032(ND5)

PGEO:

67284272(ND5)

EMAC:

30862053(ND5)

ELY:	7095526(ND5)

EFO:	14412337(ND5)

PLEP:

4363292(ND5)

SLUC:

23629812(ND5)

ESP:	40141442(ND5)

PFLV:

14048232(ND5)

AFB:	13230438(ND5)

PSWI:

72130147(ND5)

MSAM:

4100036(ND5)

SCHU:

10965118(ND5)

EARM:

8382051(ND5)

CUD:	8774894(ND5)

MZE:

26037650

ONL:	8677321(ND5)

OAU:	8745949(ND5)

OLA:	805438(ND5)

OML:	13540117(ND5)

CSAI:

804085(ND5)

XMA:	6986212(ND5)

XCO:	26048198(ND5)

XHE:	8302516(ND5)

PRET:

19590705(ND5)

GAF:	805451(ND5)

CVG:	26048388(ND5)

CTUL:

26129158(ND5)

NFU:	7256393(ND5)

KMR:	804468(ND5)

ALIM:

106511533

AOCE:

4850672(ND5)

CSEM:

7996489(ND5)

POV:	808841(ND5)

SSEN:

4266850(ND5)

HHIP:

5405699(ND5)

HSP:	5405790(ND5)

SMAU:

8382082(ND5)

LCF:	3703597(ND5)

SDU:	11669697(ND5)

XGL:	7871603(ND5)

HCQ:	14658020(ND5)

SBIA:

35996594(ND5)

PTAO:

74193766(ND5)

BPEC:

YP_004935141.1

MALB:

803932(ND5)

BSPL:

23631939(ND5)

SJO:	8703822(ND5)

GMH:	808457(ND5)

SASA:

808309(ND5)

STRU:

19099185(ND5)

OTW:	KEF73_p03(ND5)

OMY:	807977(ND5)

OGO:	6383203(ND5)

ONE:	4555707(ND5)

OKI:	4955082(ND5)

OKE:	12486870(ND5)

OMM:	4657596(ND5)

SALP:

808555(ND5)

SNH:	35115227(ND5)

CCLU:

14842641(ND5)

ELS:	806656(ND5)

SFM:	3416101(ND5)

AANG:

3190263(ND5)

LOC:	807206(ND5)

PSPA:

805414(ND5)

ARUT:

17097828(ND5)

LCM:	808093(ND5)

CMK:	9385354(ND5)

RTP:	18267186(ND5)

CPLA:

7768752(ND5)

SCAU:

808303(ND5)

LERI:

11452188(ND5)

HAKA:

15333375(ND5)

PMRN:

807813(ND5)

LRJ:	9385091(ND5)

BFO:	808734(ND5)

BBEL:

806238(ND5)

SCLV:

36165648(ND5)

SPU:	2652725(ND5)

LVG:	36941443(ND5)

AJJ:	139965206 7802875(ND5)

APLC:

3907684(ND5)

AAMU:

3239019(ND5)

SKO:	3703609(ND5)

DME:	Dmel_CG34083(ND5)

DSE:	2760943(ND5)

DSI:

DYA:

DMN:

DGR:

CCAT:

808522(ND5)

BOD:	2717265(ND5)

BDR:	125780313 4657576(ND5)

AOQ:	79023091(ND5)

TDA:	119662529 119664663 119664759 119664940 119687679 119688640

MDE:	20358590(ND5)

LSQ:	5469272(ND5)

ECOE:

35199158(ND5)

HIS:	33350938(ND5)

AGA:	85940928(ND5)

ACOZ:

26121330(ND5)

AARA:

26121216(ND5)

AMER:

26121520(ND5)

AMAP:

73620783(ND5)

AFUN:

76054180(ND5)

AMOU:

73620859(ND5)

AMRS:

73620821(ND5)

ANIL:

73620935(ND5)

ADAR:

73621011(ND5)

AAG:	33307567(ND5)

AALB:

3260121(ND5)

CQU:

140746637 140757095 140757096

CPII:

10200334(ND5)

CBRI:

87696344(ND5)

PPAP:

129809025 129809032 26044658(ND5)

ACER:

9385644(ND5)

ALAB:

34829167(ND5)

AFLR:

15822489(ND5)

BAFF:

126926940

OLG:

117611526

SOC:	9977795(ND5)

VEM:	27912170(ND5)

HST:

109504533

PMEC:

138936486 138944070

LHU:	137001858 137001863 42265452(ND5)

PGC:

109863323

VVE:	33194935(ND5)

TPRE:

111693313

LBD:	127282340 127290669

CGLO:

123268625 123269905

DAM:

114841684

AGIF:

63649833(ND5)

CCIN:

107274029 7872298(ND5)

DSM:

124415518

NPT:	124224115 124224125 124224126 124224127

NFB:	124187549 124187556 124187557 124187564

NLO:

107220241

NVG:

124298710

AROA:

110117282

TCA:	803820(ND5)

TMOL:

138140758

SOY:	28481411(ND5)

AGRG:

126750054

ATD:	34926377(ND5)

AGB:	4171603(ND5)

APLN:

28479649(ND5)

BMOR:

809258(ND5)

BMAN:

804655(ND5)

MSEX:

5848755(ND5)

DPL:	AGL76305(ND5)

PMAC:

13080347(ND5)

PPOT:

106103432 106110403 20159563(ND5)

PXU:	106118026 26836891(ND5)

PRAP:

11030474(ND5)

PNAP:

60241353(ND5)

LSIN:

126970494 126977208

HAW:	9977718(ND5)

HZE:	71203141(ND5)

TNL:	113502883 113502884 44149097(ND5)

SLIU:

17427400(ND5)

ATRA:

26281602(ND5)

GMW:	26376098(ND5)

ECLR:

PXY:	20834452(ND5)

PGW:	73956688(ND5)

CSTB:

134752633

CFUM:

36490491(ND5)

CFEL:

113381106

API:	7055881(ND5)

DNX:	17428415(ND5)

AGS:	19909106(ND5)

BTAB:

109032793 3077229(ND5)

DCI:	108253984 108254437 27914378(ND5)

CLEC:

27787581(ND5)

HHAL:

8457888(ND5)

NLU:	120352486 120352971 16216532(ND5)

LDA:	7996605(ND5)

HVI:	124361009 3332285(ND5)

MQU:	32891629(ND5)

FOC:	YP_006576366

TPAL:

38092135(ND5)

ZNE:	110840500 20004825(ND5)

CSEC:

111864191

PAME:

138698024

SGRE:

73491808(ND5)

BROR:

134540900

FCD:

110860274

DPX:	AAD33237(ND5) DAPPUDRAFT_29116

DMK:	24147215(ND5)

AFRA:

136028491 136040718 136042088 807788(ND5)

PVM:	138863175 5333211(ND5)

PJA:	3416051(ND5)

PCHN:

5333401(ND5)

PMOO:

808986(ND5)

HAME:

10743677(ND5)

PCLA:

11763607(ND5)

CQD:	138853349 17728525(ND5)

PTRU:

1482833(ND5)

SPRM:

7768775(ND5)

ESN:	3355540(ND5)

MNZ:	10200249(ND5)

MRJ:	3293141(ND5)

PORN:

10094402(ND5)

HAZT:

38169099(ND5)

OOT:	9481012(ND5)

TCF:	4788300(ND5)

DSV:	23630426(ND5)

DALB:

139054071

RSAN:

808362(ND5)

RMP:	18250942(ND5)

VDE:	806162(ND5)

TUT:	6164217(ND5)

DPTE:

113798153 7564654(ND5)

CSCU:

111636266

ABRU:

19591986(ND5)

LPOL:

803781(ND5)

CEL:	KEF34_p01(ND5)

CBR:

NAI:	804821(ND5)

BMY:	KEF88_p01(ND5)

LOA:	LOAG_15579 ND5

TSP:

HRO:	HELRODRAFT_93011

PCAN:

19909187(ND5)

LSAX:

28261526(ND5)

BARL:

143298980 17960494(ND5)

BGT:	2746319(ND5)

HRF:	35985152(ND5)

HRJ:	2846697(ND5)

CRG:	808832(ND5)

CANU:

7865913(ND5)

MYI:	4910445(ND5)

YBA:	132545982 132563024

MMER:

55289782(ND5)

RPHI:

29141292(ND5)

MAEA:

20159503(ND5)

OBI:	27205963(ND5)

OSN:	62676647(ND5)

LJP:	135481431 135481432 135481433 135481434 135481435 135481458 135481462 79134709(ND5)

LAK:	C2G87_mgp04(ND5)

SMM:

127240793 127240804 127240805

SHX:	4097437(ND5)

EGL:	41697845(nad5)

ATEN:

41854794(ND5)

ADF:	17674600(ND5)

PDAM:

5580402(ND5)

SPIS:

6798793(ND5)

DGT:	8656273(ND5)

XEN:

124455315

HMG:	6904230(ND5)

HSY:	130626885 130626917

RES:	33911777(ND5)

TAD:	TradoM_p08(ND5)

AQU:	4794342(ND5)

ATH:	DA397_mgp37(nad5)

CRB:	40490657(nad5)

BRP:	56140990(nad5)

BNA:	4237891(nad5)

RSZ:	13630175(nad5)

CPAP:

7441424(nad5)

CIT:	36487067(nad5)

GRA:	27429635(nad5)

GAB:	33134350(nad5)

EGR:	38466614(nad5)

RARG:

125313384

GMX:	15308533(nad5)

GSJ:	114404703 38334472(nad5)

PVU:	137835347 42317413(nad5)

VRA:

106754277

MTR:	26974361(nad5)

TPRA:

55290668(nad5)

PSAT:

VVO:

PCIN:

PMUM:

MDM:	13630239(nad5)

MSYL:

73938886(nad5)

PXB:

108865865

ZJU:	27215289(nad5)

CSAV:

27215500(nad5)

CSV:	11123919(nad5)

BHJ:

120085313

RCU:	10221447(nad5) 8267601

MESC:

42317544(nad5)

QLO:

115986363

VVI:	7498671(nad5)

SPEN:

34926037(nad5)

CANN:

124886414 19988965(nad5)

NTA:	142173831 3205268(nad5)

NSY:	27214838(nad5)

NAU:	35198985(nad5)

INI:	29082041(nad5)

SSPL:

121789902 121789909

SMIL:

18126426(nad5)

APAN:

HAN:	18250966(nad5)

ECAD:

122584438 122597129

LSV:	40498719(nad5) 40498783(nad5)

DCR:	135150747 88614172(nad5)

AGRV:

68216372(orf399a) 68216387(nad5)

CSIN:

40867581(nad5)

AEW:	88577597(nad5)

BVG:	809480(orf399) 809558(nad5)

SOE:	33876624(nad5)

CQI:	39331938(nad5)

ATRI:

130827033

SLAF:

9725781(nad5)

NNU:	28482646(nad5)

MING:

122071015

TSS:	122647048 122647141

PSOM:

113281654

OSA:	6450143(nad5)

DOSA:

nad5

TAES:

34688745(nad5)

HVG:

123442467

SBI:	4306039(nad5)

PVIR:

120693825 120694672

PDA:	11542550(nad5)

NCOL:

126410203 36487312(nad5)

PPP:	3989059(nad5)

CRE:	ChrepMp03(nad5)

CSL:	CospCoM_p18(nad5)

CVR:	OJ20_p03(nad5)

APRO:

ChprMp029(nad5)

OTA:	OstapMp36(nad5)

BPG:	BathyMg00080(nad5)

MIS:	MicpuN_mit25(nad5)

CCP:	ChcroMp18(nad5)

DHA:

PGU:	PGUG_05917

LBG:	89432246(nad5)

CAL:	CaalfMp13(NAD5)

CLUS:

16792572(nad5)

YLI:	802600(nd1-i2) 802612(nd5-i1) 802624(nd5)

SLB:	AWJ20_5368

NCR:	NCU16011 NCU16012

PAN:	PoanfMp36(nad5)

MTM:	MYCTH_2054219

CTHR:

CTHT_m000370

SSCK:

SPSK_11057

FGR:	GizefMp08(nad5)

PTKZ:

MRV25_mgp10(nad5)

VAL:	VDBG_17010

CLUP:

AYB75_mgp11(nad5)

SSL:	SS1G_20006

ANI:	ANID_20001

ANG:	Asnifp15(nad5)

ALUC:

EJ508_mgp03(nad5)

CPW:	90965897(nad5)

PNO:	SNOGp09(nad5)

BZE:	COCCADRAFT_111281

BOR:	COCMIDRAFT_41738

KSH:	87952606(IL334_000475) 87952607(IL334_000476) 87952634(IL334_000503) 87952635(IL334_000504)

MRT:	D9L16_mgp08(nad5)

PSTR:

EFH26_mgp11(nad5)

DDI:	DidioMp38(nad5)

DFA:	Difao_mp45(nad5)

TET:	TepyoMp33(nad5)

PSOJ:

PhsooMp22(nad5)

BLAC:

38665131(nad5)

Reference

PMID:2507335

Authors

Corral M, Paris B, Baffet G, Tichonicky L, Guguen-Guillouzo C, Kruh J, Defer N

Title

Increased level of the mitochondrial ND5 transcript in chemically induced rat hepatomas.

Journal

Exp Cell Res 184:158-66 (1989)
DOI:10.1016/0014-4827(89)90374-1

Sequence

[rno:26202]

LinkDB

ORTHOLOGY: K03884

Entry

K03884                      KO

Symbol

ND6

Name

NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00142

NADH:ubiquinone oxidoreductase, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00068

Leber hereditary optic atrophy

H00473

Mitochondrial complex I deficiency

H01347

MELAS syndrome

H01355

Kearns-Sayre syndrome

H01365

Leber hereditary optic neuropathy and dystonia

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
  09159 Environmental adaptation
   04714 Thermogenesis
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
   05012 Parkinson disease
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
   05014 Amyotrophic lateral sclerosis
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
   05016 Huntington disease
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
   05020 Prion disease
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
   05022 Pathways of neurodegeneration - multiple diseases
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03884  ND6; NADH-ubiquinone oxidoreductase chain 6
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    K03884  ND6; NADH-ubiquinone oxidoreductase chain 6

Other DBs

GO:

TC:

Genes

HSA:

4541(ND6)

PTR:	807861(ND6)

PPS:	807873(ND6)

GGO:	6742680(ND6)

PON:	129058821 808476(ND6)

PPYG:

129034756 807911(ND6)

NLE:	16545232(ND6)

SSYN:

9072800(ND6)

MCC:	2846632(ND6)

MCF:	7857748(ND6)

CSAB:

4097499(ND6)

CATY:

26408645(ND6)

PANU:

116273132 14444640(ND6)

TGE:	14216792(ND6)

RRO:	4171545(ND6)

RBB:	10549378(ND6)

TFN:	18985083(ND6)

CJC:	22203911(ND6)

SBQ:	13228908(ND6)

ANAN:

13230277(ND6)

CSYR:

7944471(ND6)

MMUR:

26823993(ND6)

LCAT:

68929167(ND6)

PCOQ:

6458119(ND6)

MMU:	17722(ND6)

MCAL:

20832253(ND6)

MPAH:

36165329(ND6)

RNO:	26203(ND6)

MCOC:

34683016(ND6)

MUN:	18129815(ND6)

CGE:	3979181(ND6)

MAUA:

8457934(ND6)

PROB:

30213855(BOP69_gp02)

PLEU:

36275537(ND6)

NGI:	15088434(ND6)

HGL:	10201220(ND6)

CPOC:

808637(ND6)

DSP:

122102014

ITI:	24576601(ND6)

OCU:	808223(ND6)

OPI:	2717274(ND6)

GVR:	804970(ND6)

CFA:	804485(ND6)

VVP:	4355763(ND6)

VLG:	23629757(ND6)

NPO:	8690251(ND6)

AML:	5179730(ND6)

UMR:	804872(ND6)

UAR:	804843(ND6)

LLV:	71922429(ND6)

MNP:	132008773 20466149(ND6)

MLK:

131838648

NVS:	14841850(ND6)

EJU:	805019(ND6)

ZCA:	4355800(ND6)

MLX:	4355876(ND6)

LWW:	4355838(ND6)

FCA:	807930(ND6)

PYU:	26129857(ND6)

PCOO:

11473375(ND6)

PBG:	26129477(ND6)

PVIV:

26129629(ND6)

LGF:	26130199(ND6)

AJU:	2654013(ND6)

PPAD:

6262380(ND6)

PUC:	125921742 6262412(ND6)

PLEZ:

26129515(ND6)

HHV:	14842166(ND6)

BTA:	3283888(ND6)

BOM:	22161777(ND6)

BIU:	2885971(ND6)

BJV:	7901818(ND6)

BBUB:

60338993(ND6)

CHX:	1485867(ND6)

OAS:	808259(ND6)

OCAN:

11030008(ND6)

BTAX:

8250971(ND6)

CSUM:

14841696(ND6)

ODA:	11452036(ND6)

CCAD:

59433112(ND6)

MREE:

805181(ND6)

OVR:	10322923(ND6)

MBEZ:

7872553(ND6)

SSC:	808512(ND6)

CFR:	5326221(ND6)

CBAI:

5309938(ND6)

CDK:	5618963(ND6)

VPC:	809421(ND6)

BMUS:

118892845 807742(ND6)

LVE:	103085270 3802091(ND6)

OOR:	72909403(ND6)

LALB:

2658634(ND6)

DLE:	31413006(ND6)

PCAD:

809411(ND6)

ECB:	807848(ND6)

EPZ:	19019458(ND6)

EAI:	808057(ND6)

MYB:	20964703(ND6)

MYD:	22203928(ND6)

MMYO:

26889510(ND6)

MLF:	27214801(ND6)

DRO:	17046628(ND6)

AJM:	808345(ND6)

HAI:	13539876(ND6)

PALE:

17963508(ND6)

MJV:	24019680(ND6)

TOD:	38289039(D9W85_mgp02)

LAV:	808795(ND6)

ETF:	802336(ND6)

DNM:	808130(ND6)

MDO:	3074664(ND6)

GAS:	63652819(ND6)

SHR:	13826444(ND6)

AFZ:	65342063(ND6)

PCW:	4108301(ND6)

TVP:	803533(ND6)

OAA:	808706(ND6)

GGA:	39116944(ND6)

PCOC:

10609907(ND6)

MGP:	5848006(ND6)

CJO:	804663(ND6)

LMUT:

31079475(ND6)

NMEL:

32282799(ND6)

APLA:

5405816(ND6)

ACYG:

18887310(ND6)

CATA:

7996708(ND6)

AFUL:

19909407(ND6)

TGU:	3950802(ND6)

LSR:	26897977(ND6)

SCAN:

37275799(ND6)

PMOA:

20355708(ND6)

OTC:	22548470(ND6)

PRUF:

17674388(ND6)

FAB:	16027892(ND6)

PHI:	9481004(ND6)

PMAJ:

39089593(ND6)

CCW:	71712363(ND6)

ACOE:

60235436(ND6)

MMEA:

20357144(ND6)

SATI:

5846192(ND6)

FPG:	808598(ND6)

FCH:	23808609(ND6)

AGEN:

7256437(ND6)

EGZ:	18985259(ND6)

NNI:	4108704(ND6)

PADL:

26737702(ND6)

GSTE:

3416059(ND6)

CLV:	8890007(ND6)

GAME:

14840903(ND6)

RTD:	84348673(ND6)

AROW:

62676612(ND6)

NPD:	62676491(ND6)

DNE:	803258(ND6)

ASN:	806133(ND6)

AMJ:	808247(ND6)

CPOO:

4108083(ND6)

GGN:	4178394(ND6)

PSS:	2943127(ND6)

CIZ:	25099112(ND6)

CMY:	808650(ND6)

CCAY:

11747796(ND6)

CPIC:

18983005(ND6)

CABI:

60253661(ND6)

ACS:	6385982(ND6)

PVT:	3338365(ND6)

PBI:	YP_008083610

PMUR:

15822641(ND6)

PMUA:

7056471(ND6)

ZVI:	24146085(YC27_gp02)

GJA:	26044412(ND6)

EMC:	30861801(ND6)

XLA:	2642079(ND6)

XTR:	3283503(ND6)

NPR:	24020222(ND6)

ACAT:

17427719(ND6)

PADS:

41662627(ND6)

BGAR:

4356055(ND6)

MUO:	18490103(ND6)

GSH:	14469880(ND6)

DRE:	140536(ND6)

SRX:	24419190(ND6)

SANH:

24419940(ND6)

SGH:	8382173(ND6)

CCAR:

807762(ND6)

CGIB:

9222075(ND6)

PTET:

5787385(ND6)

LROH:

12079587(ND6)

OMC:	18668128(ND6)

PPRM:

26048327(ND6)

MAMB:

5912293(ND6)

CIDE:

5857706(ND6)

CERY:

20160556(ND6)

MASI:

3131133(ND6)

TROS:

14048446(ND6)

TDW:	36952174(ND6)

MANU:

6879720(ND6)

PDAB:

18668407(ND6)

IPU:	804886(ND6)

IFU:	26118470(ND6)

PHYP:

16216577(ND6)

SMEO:

10079908(ND6)

TVC:	10079797(ND6)

CGAR:

25103320(ND6)

CHAR:

5228436(ND6)

TRU:	805212(ND6)

TFS:	19524542(ND6)

TNG:	BAE79228(ND6)

LCO:	7095392(ND6)

NCC:	10752034(ND6)

PGEO:

67284275(ND6)

EMAC:

30862054(ND6)

ELY:	7095527(ND6)

EFO:	14412338(ND6)

PLEP:

4363293(ND6)

SLUC:

23629813(ND6)

ESP:	40141417(ND6)

PFLV:

14048233(ND6)

AFB:	13230439(ND6)

PSWI:

72130130(ND6)

MSAM:

4100037(ND6)

SCHU:

10965110(ND6)

EARM:

8382050(ND6)

CUD:	8774895(ND6)

MZE:

26037626

ONL:	8677322(ND6)

OAU:	8745950(ND6)

OLA:	805436(ND6)

OML:	13540118(ND6)

CSAI:

804087(ND6)

XMA:	6986214(ND6)

XCO:	26048175(ND6)

XHE:	8302517(ND6)

PRET:

19590704(ND6)

GAF:	805444(ND6)

CVG:	26048365(ND6)

CTUL:

26129135(ND6)

NFU:	7256395(ND6)

KMR:	804463(ND6)

AOCE:

4850668(ND6)

CSEM:

7996490(ND6)

POV:	808840(ND6)

SSEN:

4266851(ND6)

HHIP:

5405711(ND6)

HSP:	5405807(ND6)

SMAU:

8382083(ND6)

LCF:	3703598(ND6)

SDU:	11669694(ND6)

XGL:	7871605(ND6)

HCQ:	14658021(ND6)

SBIA:

35996570(ND6)

PTAO:

74193767(ND6)

BPEC:

YP_004935142.1

MALB:

803934(ND6)

BSPL:

23631941(ND6)

SJO:	8703824(ND6)

GMH:	808451(ND6)

SASA:

808317(ND6)

STRU:

19099186(ND6)

OTW:	KEF73_p02(ND6)

OMY:	807970(ND6)

OGO:	6383211(ND6)

ONE:	4555708(ND6)

OKI:	4955086(ND6)

OKE:	12486867(ND6)

OMM:	4657590(ND6)

SALP:

808554(ND6)

SNH:	35115193(ND6)

CCLU:

14842642(ND6)

ELS:	806655(ND6)

SFM:	3416102(ND6)

AANG:

3190257(ND6)

LOC:	807207(ND6)

PSPA:

805404(ND6)

ARUT:

17097829(ND6)

LCM:	808094(ND6)

CMK:	9385355(ND6)

RTP:	18267187(ND6)

CPLA:

7768755(ND6)

SCAU:

808302(ND6)

LERI:

11452176(ND6)

HAKA:

15333376(ND6)

PMRN:

807804(ND6)

LRJ:	9385093(ND6)

BFO:	808735(ND6)

BBEL:

806232(ND6)

SPU:	2652726(ND6)

LVG:	36941418(ND6)

AJJ:	7802876(ND6)

APLC:

3907685(ND6)

AAMU:

3239008(ND6)

SKO:	3703611(ND6)

DME:	Dmel_CG34089(ND6)

DSE:	2760939(ND6)

DSI:

DYA:

DAN:	116655103 116655728

DPO:

DMN:

DHE:

DVI:

CCAT:

808520(ND6)

BOD:	138857894 2717266(ND6)

BDR:	125779684 4657579(ND6)

AOQ:	79023097(ND6)

ALUD:

128864711

MDE:	20358587(ND6)

LSQ:	119601150 5469275(ND6)

ECOE:

35199161(ND6)

HIS:	119648570 33350941(ND6)

AGA:	85940931(ND6)

ACOZ:

26121333(ND6)

AARA:

26121219(ND6)

AMER:

26121523(ND6)

AMAP:

73620789(ND6)

AFUN:

76054183(ND6)

AMOU:

73620865(ND6)

AMRS:

73620827(ND6)

ANIL:

73620941(ND6)

ADAR:

73621017(ND6)

AAG:	33307570(ND6)

AALB:

3260124(ND6)

CQU:

CPII:

10200337(ND6)

CBRI:

87696348(ND6)

BCOO:

119082526

PPAP:

26044661(ND6)

SOC:	9977798(ND6)

VEM:	27912171(ND6)

LHU:	42265455(ND6)

VVE:	33194938(ND6)

AGIF:

63649839(ND6)

CCIN:

7872301(ND6)

DSM:

124415328

TCA:	803818(ND6)

EFOR:

136349778

SOY:	28481414(ND6)

ATD:	34926347(ND6)

HAXR:

123672005

AGB:	4171593(ND6)

APLN:

28479655(ND6)

BMOR:

809261(ND6)

BMAN:

804650(ND6)

MSEX:

5848753(ND6)

DPL:	AGL76308(ND6)

PMAC:

13080337(ND6)

PPOT:

20159564(ND6)

PXU:	26836894(ND6)

PRAP:

11030475(ND6)

PNAP:

60241356(ND6)

LSIN:

126970897

HAW:	9977721(ND6)

HZE:	71203147(ND6)

TNL:	44149099(ND6)

SLIU:

17427403(ND6)

ATRA:

26281605(ND6)

GMW:	26376101(ND6)

PXY:	20834455(ND6)

PGW:	73956691(ND6)

API:	7055884(ND6)

DNX:	17428418(ND6)

AGS:	19909109(ND6)

BTAB:

3077227(ND6)

DCI:	27914381(ND6)

CLEC:

27787564(ND6)

HHAL:

8457891(ND6)

NLU:	16216535(ND6)

LDA:	7996608(ND6)

HVI:	3332281(ND6)

MQU:	32891632(ND6)

FOC:	YP_006576369

TPAL:

38092104(ND6)

ZNE:	20004826(ND6)

SGRE:

73491814(ND6)

DPX:	AAD33240(ND6)

DMK:	24147218(ND6)

AFRA:

807789(ND6)

PVM:	5333217(ND6)

PJA:	3416052(ND6)

PCHN:

5333399(ND6)

PMOO:

808974(ND6)

HAME:

10743680(ND6)

PCLA:

11763609(ND6)

CQD:	138854152 17728528(ND6)

PTRU:

1482834(ND6)

SPRM:

7768778(ND6)

ESN:	3355544(ND6)

MNZ:	10200252(ND6)

MRJ:	3293143(ND6)

PORN:

10094405(ND6)

HAZT:

38169101(ND6)

OOT:	9481015(ND6)

DSV:	23630427(ND6)

RMP:	18250945(ND6)

VDE:	806170(ND6)

ABRU:

19591989(ND6)

LPOL:

803782(ND6)

CEL:	KEF34_p12(ND6)

CBR:

NAI:	804820(ND6)

LOA:

TSP:

HRO:	HELRODRAFT_93032

PCAN:

19909183(ND6)

LSAX:

28261523(ND6)

BARL:

143298978 17960490(ND6)

BGT:	2746315(ND6)

HRF:	35985159(ND6)

HRJ:	2846699(ND6)

MYI:	4910438(ND6)

MMER:

55289787(ND6)

OBI:	27205970(ND6)

OSN:	62676640(ND6)

LJP:	79134706(ND6)

SMM:

127262840 127263625 127264279

SHX:	4097443(ND6)

ATEN:

41854783(ND6)

HMG:	6904236(ND6)

RES:	33911773(ND6)

ATH:	DA397_mgp28(nad6)

CRB:	40490680(nad6)

EUS:	EUTSA_v10029192mg

BRP:	56141058(nad6)

BNA:	4237892(nad6)

RSZ:	13630170(nad6)

CPAP:

7441431(nad6)

CIT:	36487013(nad6)

GRA:	27429631(nad6)

GHI:	121216088 121218564 24679529(nad6)

GAB:	33134352(nad6)

EGR:	38466565(nad6)

RARG:

115733562 125313372

GMX:	15308540(nad6)

GSJ:	38334451(nad6)

PVU:	42317445(nad6)

VAR:	15382784(nad6)

MTR:	26974332(nad6)

TPRA:

55290716(nad6)

PSAT:

127107959 127129380

VVO:

131634064

LJA:

130720082

ADU:	127744287 127744495 127744648 127745507 127745509

AHF:

112754620

PCIN:

129294845

MDM:	13630199(nad6)

MSYL:

73938898(nad6)

ZJU:	125419785 132803654 27215282(nad6)

MNT:	112091332 39338994(nad6)

CSAV:

27215467(nad6)

HLP:

133823296

CSV:	11123869(nad6)

RCU:	10221446(nad6)

MEAN:

126667522

MESC:

42317535(nad6)

VVI:	7498585(nad6)

SLY:	34678309(nad6)

SPEN:

34926027(nad6)

SOT:

102588211

CANN:

124899985 19989132(nad6)

LBB:

132614104

NTA:	3205263(nad6)

NSY:	27214874(nad6)

NAU:	109236428 109243048 35198967(nad6)

INI:	29082084(nad6)

SSPL:

121789911 121789922

SMIL:

18126280(nad6)

APAN:

HAN:	110896653 18250979(nad6)

BHW:

143560831

ECAD:

122587595

LSV:	40498721(nad6)

DCR:	135151253 135151263 88614213(nad6)

AGRV:

68216266(orf190a) 68216317(nad6)

CSIN:

40867579(nad6)

AEW:	88577577(nad6)

CFLO:

132290988

BVG:	809476(nad6)

SOE:	110787815 130461974 33876587(nad6)

CQI:	39331937(nad6)

ATRI:

130827072

SLAF:

9725757(nad6)

NNU:	28482642(nad6)

MING:

122081643 122086277

TSS:	122647063 122647064

OSA:	6450132(nad6)

DOSA:

nad6

OBR:

121055307

ATS:	109732985 120963057 120976899 123495099 141026276 141026607 141028098 141039330

TDC:	119272766 119287971 119287976 119288903 119303373 119306217 119333336 119342190 119363925 119367765

TAES:

123038230 123045139 123045142 123068498 123075097 123076666 123095045 123099800 123100515 123113287 123140083 123142460 123149603 123153212 123158525 123158911 123171115 34688765(nad6)

TUA:	125516601 125523570 125530203 125537091 125553844

HVG:	123399977 123416988

SBI:	4306019(nad6)

ZMA:	118472187 118473862 118473885 118474701 118475010 118475571 118475579 118475658 118475693 118476002

MFLO:

136529497

SITA:

111256052

SVS:

140221545

PVIR:

120673089 120694118 120694191

PHAI:

112891050

PDA:	11542551(nad6)

DCT:

114579427

PEQ:

110026157

AOF:	109823314 109836298

NCOL:

36487352(nad6)

CJF:	131057454 131059347 131066024 131871156 131873449

PPP:	3989060(nad6)

CRE:	ChrepMp06(nad6)

CSL:	CospCoM_p17(nad6)

CVR:	OJ20_p12(nad6)

APRO:

ChprMp006(nad6)

OTA:	OstapMp31(nad6)

BPG:	BathyMg00253(nad6)

MIS:	MicpuN_mit19(nad6_1) MicpuN_mit33(nad6_2)

CCP:	ChcroMp08(nad6)

DHA:

LBG:	89432273(nad6)

CAL:	CaalfMp02(NAD6)

CLUS:

16792602(nad6)

YLI:	802611(nd6)

NCR:

NCU16004

PAN:	PoanfMp08(nad6)

MTM:	MYCTH_43648

CTHR:

CTHT_m000070

SSCK:

SPSK_11058

FGR:	GizefMp16(nad6)

PTKZ:

MRV25_mgp02(nad6)

VAL:	VDBG_17012

CLUP:

AYB75_mgp04(nad6)

SSL:	SS1G_20011

ANI:	ANID_20011

ANG:	Asnifp08(nad6)

ALUC:

EJ508_mgp10(nad6)

PNO:

SNOGp15

CNG:	CNAG_09007

KSH:	87952631(IL334_000500)

ABP:	AGABI1DRAFT48550(AGABI1DRAFT_48550)

MRT:	D9L16_mgp12(nad6)

PSTR:

EFH26_mgp14(nad6)

DDI:	DidioMp15(nad6)

DFA:	Difao_mp15(nad6)

Reference

PMID:1417830

Authors

Johns DR, Neufeld MJ, Park RD

Title

An ND-6 mitochondrial DNA mutation associated with Leber hereditary optic neuropathy.

Journal

Biochem Biophys Res Commun 187:1551-7 (1992)
DOI:10.1016/0006-291X(92)90479-5

Sequence

[hsa:4541]

LinkDB

ORTHOLOGY: K03942

Entry

K03942                      KO

Symbol

NDUFV1

Name

NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map04932

Non-alcoholic fatty liver disease

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00143

NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00473

Mitochondrial complex I deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
   05012 Parkinson disease
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
   05014 Amyotrophic lateral sclerosis
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
   05016 Huntington disease
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
   05020 Prion disease
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
   05022 Pathways of neurodegeneration - multiple diseases
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1

Other DBs

GO:

TC:

113062166 113062366 113120013

Genes

HSA:	4723(NDUFV1)

PTR:	747209(NDUFV1)

PPS:	100990916(NDUFV1)

GGO:	101142811(NDUFV1)

PON:	100454954(NDUFV1)

PPYG:

129007675(NDUFV1)

NLE:	100580871(NDUFV1)

HMH:	116469089(NDUFV1)

SSYN:

129478606(NDUFV1)

MCC:	711412(NDUFV1)

MCF:	102124346(NDUFV1)

MTHB:

126935373

MNI:	105469694(NDUFV1)

CSAB:

103216555(NDUFV1)

CATY:

105577340(NDUFV1)

PANU:

101006922(NDUFV1)

TGE:	112606112(NDUFV1)

MLEU:

105544481(NDUFV1)

RRO:	104664727(NDUFV1)

RBB:	108518679(NDUFV1)

TFN:	117081005(NDUFV1)

PTEH:

111522229(NDUFV1)

CANG:

105512080(NDUFV1)

CJC:	100409776(NDUFV1)

SBQ:	101047545(NDUFV1)

CIMI:

108310187(NDUFV1)

ANAN:

105717626(NDUFV1)

CSYR:

103251659(NDUFV1)

MMUR:

105867420(NDUFV1)

LCAT:

123642832(NDUFV1)

ERUF:

138384675(NDUFV1)

PCOQ:

105827373(NDUFV1)

OGA:	100964599(NDUFV1)

MMU:	17995(Ndufv1)

MCAL:

110285596(Ndufv1)

MPAH:

110316888(Ndufv1)

RNO:	293655(Ndufv1)

MCOC:

116103309(Ndufv1)

ANU:	117717267(Ndufv1)

ASYL:

127693152(Ndufv1)

MUN:	110547204(Ndufv1)

CGE:	100757245(Ndufv1)

MAUA:

101827130(Ndufv1)

PROB:

127228621(Ndufv1)

PLEU:

114694751(Ndufv1)

PMAV:

102905274(Ndufv1)

MORG:

121454797(Ndufv1)

MFOT:

126498279

AAMP:

119815378(Ndufv1)

CNL:	130880721(Ndufv1)

NGI:	103725598(Ndufv1)

HGL:	101726275(Ndufv1)

CPOC:

100725831(Ndufv1)

CCAN:

109692322(Ndufv1)

DORD:

105989244(Ndufv1)

DSP:	122105042(Ndufv1)

DMER:

138818735(Ndufv1)

PLOP:

125361320(Ndufv1)

NCAR:

124960411

MMMA:

107156880(Ndufv1)

ITI:	101967499(Ndufv1)

OCU:

127486372

OPI:	101528278(NDUFV1)

OCZ:	121150019(NDUFV1)

TUP:	102468350(NDUFV1)

GVR:	103597995(NDUFV1)

CFA:	476004(NDUFV1)

CLUD:

112647056 112659341(NDUFV1)

VVP:	112924173(NDUFV1)

VLG:	121471864(NDUFV1)

NPO:	129503083(NDUFV1)

AML:	100466993(NDUFV1)

UMR:	103679522(NDUFV1)

UAH:	113244014(NDUFV1)

UAR:	123778416(NDUFV1)

ELK:

111149612

LLV:

125079144

MPUF:

101677220(NDUFV1)

MNP:	132017779(NDUFV1)

MLK:	131816609(NDUFV1)

NVS:	122913194(NDUFV1)

ORO:	101378216(NDUFV1)

EJU:	114220454(NDUFV1)

ZCA:	113915204(NDUFV1)

MLX:	118016140(NDUFV1)

MANO:

123856883(NDUFV1)

NSU:	110576051(NDUFV1)

LWW:	102730280(NDUFV1)

FCA:	101093395(NDUFV1)

PYU:	121023971(NDUFV1)

PCOO:

112852033(NDUFV1)

PBG:	122484069(NDUFV1)

PVIV:

125147019(NDUFV1)

LRUF:

124505706

LGF:	123602009(NDUFV1)

AJU:

106971097

PTG:	102964581(NDUFV1)

PPAD:

109246866(NDUFV1)

PUC:

125930443

PLEZ:

122200839(NDUFV1)

HHV:	120233944(NDUFV1)

CCRU:

144237720(NDUFV1)

BTA:	287014(NDUFV1)

BOM:	102272484(NDUFV1)

BIU:	109554559(NDUFV1)

BJV:	133241546(NDUFV1)

BBUB:

102392160(NDUFV1)

BKE:	129652250(NDUFV1)

BBIS:

104986953(NDUFV1)

CHX:	102184322(NDUFV1)

OAS:	101121129(NDUFV1)

OCAN:

138426547(NDUFV1)

BTAX:

128068660(NDUFV1)

CSUM:

138083267(NDUFV1)

ODA:	120874786(NDUFV1)

CCAD:

122431141(NDUFV1)

MREE:

136169803(NDUFV1)

OVR:	110129405(NDUFV1)

MBEZ:

129548685(NDUFV1)

SSC:	100522783(NDUFV1)

CFR:	102519984(NDUFV1)

CBAI:

105070347(NDUFV1)

CDK:	105104414(NDUFV1)

VPC:	102525385(NDUFV1)

BACU:

103003730(NDUFV1)

BMUS:

118899401(NDUFV1)

LVE:	103069803(NDUFV1)

OOR:	101289424(NDUFV1)

LALB:

132525563(NDUFV1)

GMF:	115840444(NDUFV1)

DDP:	132430132(NDUFV1)

DLE:	111183658(NDUFV1)

PCAD:

102973178 112067461(NDUFV1) 114483880

PSIU:

116758618(NDUFV1)

PPHC:

136126377(NDUFV1)

NASI:

112402423(NDUFV1)

ECB:	100059569(NDUFV1)

EPZ:	103543520(NDUFV1)

EAI:	106833485(NDUFV1)

MYB:	102246622(NDUFV1)

MYD:	102764280(NDUFV1)

MMYO:

118665210(NDUFV1)

MLF:	102426339(NDUFV1)

MDT:	132241326(NDUFV1)

MYUM:

139018821(NDUFV1)

PKL:	118706949(NDUFV1)

EFUS:

103290917(NDUFV1)

MNA:	107537435(NDUFV1)

DRO:	112317410(NDUFV1)

SHON:

118998376(NDUFV1)

AJM:	119041886(NDUFV1)

PDIC:

114500248(NDUFV1)

PHAS:

123829375(NDUFV1)

MMF:	118628491(NDUFV1)

PPAM:

129068534(NDUFV1)

HAI:	109384283(NDUFV1)

RFQ:	117031276(NDUFV1)

PALE:

102888816(NDUFV1)

PGIG:

120584746(NDUFV1)

PVP:	105306559(NDUFV1)

RAY:	107503551(NDUFV1)

MJV:	108405832(NDUFV1)

TOD:	119249895(NDUFV1)

SARA:

101552131(NDUFV1)

SFUM:

130039831(NDUFV1)

SETR:

126018795(NDUFV1)

LAV:	100669323(NDUFV1)

TMU:

101342189

ETF:	101654446(NDUFV1)

DNM:	101437750(NDUFV1)

MDO:	100013993(NDUFV1)

GAS:	123252812(NDUFV1)

SHR:	100934645(NDUFV1)

AFZ:

127539745

PCW:	110195468(NDUFV1)

TVP:	118855388(NDUFV1)

PBRV:

138144926(NDUFV1)

MLAO:

141516617(NDUFV1)

OAA:	100092852(NDUFV1)

TACU:

119943386(NDUFV1)

GGA:	430210(NDUFV1)

PCOC:

116237857(NDUFV1)

MGP:	100547569(NDUFV1)

CJO:	107314148(NDUFV1)

TPAI:

128087103(NDUFV1)

LMUT:

125695322(NDUFV1)

NMEL:

110401481(NDUFV1)

APLA:

101802630(NDUFV1)

AACU:

137858082(NDUFV1)

OJA:	118157311(NDUFV1)

ACYG:

106048251(NDUFV1)

CATA:

118244694(NDUFV1)

AFUL:

116490155(NDUFV1)

TGU:	100220058(NDUFV1)

LSR:	110485014(NDUFV1)

VMC:	128809497(NDUFV1)

VCHA:

128790062(NDUFV1)

AIB:	137476358(NDUFV1)

SCAN:

103822294(NDUFV1)

PMOA:

120503639(NDUFV1)

OTC:	121336779(NDUFV1)

PRUF:

121352335(NDUFV1)

ATRC:

139590402(NDUFV1)

MATE:

118687669(NDUFV1)

MAEN:

136557729(NDUFV1)

FAB:	101812104(NDUFV1)

OMA:	130254526(NDUFV1)

PHI:	102100987(NDUFV1)

PMAJ:

107205250(NDUFV1)

CCAE:

111930511(NDUFV1)

CCW:	104692994(NDUFV1)

CBRC:

103615231(NDUFV1)

ACOE:

138111254(NDUFV1)

ETL:	114067949(NDUFV1)

ZLE:	135448852(NDUFV1)

ACHL:

103809254(NDUFV1)

SVG:	106854798(NDUFV1)

MMEA:

130583344(NDUFV1)

HRT:	120753730(NDUFV1)

SATI:

136362309(NDUFV1)

CFAI:

136291918(NDUFV1)

CCIC:

134044950(NDUFV1)

FPG:	101921595(NDUFV1)

FCH:	102046706(NDUFV1)

FRS:	119154360(NDUFV1)

SHAB:

115606965(NDUFV1)

ACUN:

113481039(NDUFV1)

ANOC:

141966043(NDUFV1)

SURA:

141950438(NDUFV1)

TALA:

116962502(NDUFV1)

ACHC:

115351601(NDUFV1)

HLE:	104829821(NDUFV1)

AGEN:

126047117

HHAR:

128153099(NDUFV1)

BBUT:

142040466(NDUFV1)

GCL:

127017383

DPUB:

104299765(NDUFV1)

PPUS:

135186004(NDUFV1)

IIN:	128974128(NDUFV1)

NNI:	104020536(NDUFV1)

PARX:

142058048(NDUFV1)

CBOR:

142088312(NDUFV1)

CBOY:

140653646(NDUFV1)

MAME:

142410004(NDUFV1)

CLV:	102094634(NDUFV1)

CNIC:

135989535(NDUFV1)

MUI:	104539133(NDUFV1)

CUCA:

104064468(NDUFV1)

PCUR:

138720862(NDUFV1)

TEO:	104378955(NDUFV1)

GAME:

129207360(NDUFV1)

CPEA:

104395866(NDUFV1)

CVF:	104293022(NDUFV1)

RTD:	128909625(NDUFV1)

CRID:

134514959(NDUFV1)

LMIC:

141742945(NDUFV1)

NARQ:

141465662(NDUFV1)

AAM:	106487915(NDUFV1)

AROW:

112969085(NDUFV1)

NPD:	112955500(NDUFV1)

TGT:	104576878(NDUFV1)

DNE:	112993469(NDUFV1)

SCAM:

104149112(NDUFV1)

ASN:	102380458(NDUFV1)

AMJ:	102562449(NDUFV1)

PSS:	102455094(NDUFV1)

CIZ:	142014903(NDUFV1)

CMY:	102944248(NDUFV1)

CCAY:

125638232(NDUFV1)

LKP:	140912380(NDUFV1)

NDS:	141988635(NDUFV1)

DCC:	119857225(NDUFV1)

CPIC:

101949730(NDUFV1)

TST:	117873100(NDUFV1)

EOB:	135877531(NDUFV1)

CABI:

116822188(NDUFV1)

MRV:	120404962(NDUFV1)

ACS:	100562726(ndufv1)

ASAO:

132772471(NDUFV1)

PVT:	110078373(NDUFV1)

SUND:

121919488(NDUFV1)

PBI:	103052075(NDUFV1)

PMUR:

107290801(NDUFV1)

CTIG:

120308304(NDUFV1)

TSR:	106546213(NDUFV1)

PGUT:

117667079(NDUFV1)

PCAE:

139308062(NDUFV1)

APRI:

131183956(NDUFV1)

PTEX:

113450208(NDUFV1)

NSS:	113423819(NDUFV1)

VKO:	123019719(NDUFV1)

PMUA:

114600913(NDUFV1)

PRAF:

128418172(NDUFV1)

ZVI:	118089491(NDUFV1)

HCG:	128339568(NDUFV1)

GJA:	107112620(NDUFV1)

STOW:

125425849(NDUFV1)

EMC:	129325121(NDUFV1)

XLA:	379907(ndufv1.L)

XTR:	496988(ndufv1)

NPR:	108800259(NDUFV1)

RTEM:

120909186(NDUFV1)

ACAT:

141106342(NDUFV1)

PADS:

140339536(NDUFV1)

BBUF:

121003357(NDUFV1)

BGAR:

122941526(NDUFV1)

DTC:	141076087(NDUFV1)

HSQ:	130282665(NDUFV1)

PCOB:

135054919(NDUFV1)

PWL:	138293683(NDUFV1)

MUO:	115482592(NDUFV1)

GSH:	117348384(NDUFV1)

DRE:	445291(ndufv1)

SRX:	107724096(ndufv1) 107739579

SANH:

107693353

SGH:	107589403 107599567

CCAR:

109102871 109108713

CAUA:

CGIB:

127935776 127979024

PTET:

122323990(ndufv1)

LROH:

127182022(ndufv1)

OMC:	131525294(ndufv1)

PPRM:

120483679(ndufv1)

RKG:	130070818(ndufv1)

MAMB:

125275546(ndufv1) 125275957

CIDE:

127501432

CERY:

137037507(ndufv1)

MASI:

127421460 127425617

TROS:

130567491(ndufv1)

TDW:	130415547(ndufv1)

MANU:

129455671(ndufv1)

PDAB:

135777005(ndufv1)

IPU:

108273250

IFU:	128615245(ndufv1)

PHYP:

113535185(ndufv1)

SMEO:

124382205(ndufv1)

TFD:	113641280(ndufv1)

TVC:	132842879(ndufv1)

CGAR:

128515568(ndufv1)

NGRA:

132870922(ndufv1)

TRN:	134329883(ndufv1)

AMEX:

103023083(ndufv1) 103028601

CMAO:

118805982(ndufv1) 118814521

EEE:	113572616(ndufv1)

CHAR:

105902023(ndufv1) 105913003

SPIL:

134072683(ndufv1) 134081994 134082422

ASAD:

121696308(ndufv1) 121721515

TRU:	101067620 101076777 115251755

TFS:	130518584(ndufv1) 130532970

TNG:	GSTEN00038859G001

LCO:	104920536 104927556(ndufv1)

NCC:

104963773

TBEN:

117478316(ndufv1) 117480381

CGOB:

115015835 115021381

PGEO:

117455561(ndufv1) 117461345

GACU:

117533456 117542541(ndufv1)

EMAC:

134861632 134874914(ndufv1)

ELY:	117263016(ndufv1) 117266245

EFO:	125893242 125904693(ndufv1)

PLEP:

121939703 121939705 121955411 121957783

SLUC:

116047345(ndufv1) 116049602

SVIT:

144518955 144528901(ndufv1)

ECRA:

117946728 117956885(ndufv1)

ESP:	116690648 116701666

PFLV:

114557943 114568121(ndufv1)

PFLT:

120562542 120571631(ndufv1)

GAT:	120826851(ndufv1)

PPUG:

119218779(ndufv1)

AFB:	129097167(ndufv1) 129108981

CLUM:

117738923 117745804

PSWI:

130193075(ndufv1) 130213249

CANA:

137781658 137784709(ndufv1)

CVE:	137872742(ndufv1) 137891027

AMIR:

142965235(ndufv1) 142969490

MSAM:

119897537 119907278(ndufv1)

SCHU:

122864895(ndufv1) 122881529

EARM:

139290501 139298808(ndufv1)

CUD:	121514031 121523184(ndufv1)

SPUL:

138584507 138608795(ndufv1)

LMIX:

132983872 132990827(ndufv1)

HTC:	141801130 141802968(ndufv1)

ALAT:

119005638 119016572(ndufv1)

ASTR:

137607823(ndufv1)

PKLU:

139205506 139215112(ndufv1)

MZE:	101480862(ndufv1) 101485676

ONL:	100699226(ndufv1) 100712213

OAU:	116320026(ndufv1) 116321055

OLA:	101175005(ndufv1)

OML:	112162637(ndufv1)

CSAI:

133433079 133461412(ndufv1)

XMA:	102224224 102229571

XCO:	114140629 114156623(ndufv1)

XHE:	116717272 116730677

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

129371112 129375197(ndufv1)

CVG:	107088823 107101109

CTUL:

119779626(ndufv1) 119783068

GMU:	124879633(ndufv1)

NFU:	107394640(ndufv1)

KMR:	108237749(ndufv1)

ALIM:

106518116(ndufv1)

NWH:	119425865(ndufv1)

AOCE:

111571368(ndufv1) 111586460

EJA:	138194163 138214781(ndufv1)

BFRE:

138618237(ndufv1) 138619394

MCEP:

125015960 125020213(ndufv1)

CSEM:

103394166(ndufv1)

POV:	109633052 109638763

SSEN:

122786929(ndufv1)

SSOE:

131446949(ndufv1)

HHIP:

117770571(ndufv1) 117776429

HSP:	118113854 118124316(ndufv1)

PPLT:

128449094 128461577(ndufv1)

SMAU:

118291692(ndufv1) 118310952

LCF:	108885897 108888872

SDU:	111223237 111229987

SLAL:

111652173 111657622

XGL:	120784423 120785951(ndufv1)

HCQ:	109514576 109515284

SSCV:

125974946 125987228(ndufv1)

SBIA:

133499538(ndufv1) 133501109

PEE:	133395627(ndufv1) 133401940

PTAO:

133471265(ndufv1)

BPEC:

110161132(ndufv1)

ENY:	140361994(ndufv1)

MALB:

109973919(ndufv1)

BSPL:

114866264(ndufv1)

SJO:	128366471 128374042(ndufv1)

SSCO:

133983355 133996340(ndufv1)

TTY:	137191351 137198785(ndufv1)

GMH:	115536218(ndufv1) 115553957

SASA:

106588156(NDUV1) 106605789

STRU:

115173260 115177176 115189400

OTW:	112236077 112242135 112266611(ndufv1)

OMY:	110495982(ndufv1) 110508594

OGO:	123997126 124005877 124029392

ONE:	115128181(ndufv1) 115147016

OKI:	109883762 109886461 109907713

OKE:	118374775 118381981

OMM:	135521330 135523049 135552447(ndufv1)

OCLA:

139373294 139379407

SALP:

111955914(ndufv1) 112072239

SNH:	120022560(ndufv1) 120030934

SFON:

129819510(ndufv1) 129837491

CCLU:

121543876 121571391 121586286

ELS:	105007525(ndufv1) 105018964

OEP:	134006678 134023658

SFM:	108924197 108931744

PKI:	111843338(ndufv1)

AANG:

118208463 118234352

AROT:

135233672 135261933

CCOG:

133136405(ndufv1)

LOC:	102689030 102696092

PSPA:

121302106(ndufv1)

PSEX:

120538272(ndufv1)

LCM:	102360790(NDUFV1)

RTP:	109937321(ndufv1)

HOC:	132834475(ndufv1)

PMRN:

116939225(NDUFV1)

LRJ:	133348243 133348328

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LPIC:

LVG:	121418018 121419324

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG11423(ND-51L1) Dmel_CG8102(ND-51L2) Dmel_CG9140(ND-51)

DER:	26526366 6543518 6546770

DSE:	116800658 6609268 6613578

DSI:	Dsimw501_GD22602(Dsim_GD22602) Dsimw501_GD25625(Dsim_GD25625) Dsimw501_GD28801(Dsim_GD28801)

DYA:	Dyak_GE12249 Dyak_GE18950 Dyak_GE28188

DAN:	26515253 6498216

DSR:	110185632 110190984

DPO:	15382901 4803358 4817872

DPE:	113565230 113565883 6589230 6591252

DMN:	108158476 108159625 108163771 117187819 117191076

DWI:	26529173 6642374

DGR:	116804946 6560746 6562381

DMO:	Dmoj_GI13499 Dmoj_GI19938 Dmoj_GI26293

DAZ:	108609965 108615850 108616220

DNV:	108654052 115563331 115564570

DHE:	111596347 111597032

DVI:	26531775(ND-51L1) 6628246(ND-51)

CCAT:

101451347 101460952

BOD:	106621619 106624109(ND-51)

BDR:	105223380 105227337

RZE:	108365930 108381039

AOQ:	129239492 129248348

ALUD:

128856654 128864003

TDA:	119670860 119671407 119676716 119687900

MDE:	101890524 101897732

SCAC:

106092863

LCQ:

111682794

LSQ:	119610149 119611657

CVJ:	135950033(ND-51) 135955162 135959083

GFS:	119633082 119642401

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ANIL:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006281

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:	122529296 122529297

CCAL:

OBB:

OLG:

MGEN:

APUR:

144475430(Nd-51)

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108730177(ND-51)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139113333(Nd-51)

TLN:	139812425(Nd-51)

TAME:

143899606(Nd-51)

TNY:	139787038(Nd-51)

HST:

DQU:

CFO:

FEX:

PMEC:

138934053(Nd-51)

LHU:	105678469(ND-51)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100122492(Ndufv1)

CSOL:

TPRE:

LHT:

LBD:

MDL:	103568139 103573030

CGLO:

123263081 123264440

CTYP:

141528114(Nd-51) 141536189

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124220385(ND-51)

NFB:

NLO:

NVG:

AROA:

TCA:	659459(nuoF)

TMOL:

138130925

DPA:

109543241

ESIM:

136414720

EFOR:

136341880(ND-51)

SOY:

115882995

RFG:	143193177(ND-51)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:	111505824 111516543

DVV:

126890063

NVL:

108557781

DCOR:

135796554(ND-51)

APLN:

108745091

PPYR:

116171031 116171042 116171428 116171483 116176054

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_207628

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:	119836950 119837049

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

ECLR:

140747992(ND-51)

PXY:

PGW:

LGLY:

CSTB:

CFUM:

141426414(ND-51)

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

106691581(ND-51)

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM463680

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138710911(ND-51)

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_53209

DMK:

DPZ:

DCAR:

AFRA:

PVM:	113820765(ND-51)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

SPRM:

ESN:

MNZ:	135197202 135197203

MRJ:

136841592

PORN:

139761970

HAZT:

108681576

OOT:	143023214 143034480

EAF:

111708344

LSM:	121118223(ND-51)

TCF:

PPOI:

ISC:

DSV:

DALB:

135910509(ND-51)

RSAN:

119372016

RMP:	119163258(ND-51)

HLG:	144158734(Nd-51)

OTI:

135396432

VDE:

111249888

VJA:

111262963

GOE:	100900643 100906081

TUT:	107359100 107367469

DPTE:

113793757

DFR:	124495971(ND-51)

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_C09H10.3(nuo-1)

CBR:	CBG_02970(Cbr-nuo-1)

CRQ:	GCK72_005417

NAI:	NECAME_05690

BMY:	BM_BM2121(Bma-nuo-1)

LOA:	LOAG_00610

TSP:

Tsp_02641

HRO:	HELRODRAFT_104983

LGI:	LOTGIDRAFT_175100

PVUL:

PCAN:

LSAX:

BARL:

BGT:	106075130 106077951

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_010710

SHX:	MS3_00009478(NDUFV1_1)

OVI:	T265_08967

LLON:

NVE:

EPA:

ATEN:

ADF:	107336901 107336903

AMIL:

AMUA:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_28664

AQU:

100631530

CCLM:

134195322

ATH:	AT5G08530(CI51)

ALY:

9309437

CRB:

17882496

CSAT:

104708228 104734882 104740504 104769071

EUS:	EUTSA_v10013394mg

BRP:	103847166 103855792

BNA:	106384960 106419325 111210094 125575000

BOE:	106318592 106335877

RSZ:	108817836 108845826

THJ:	104818400 104819362

CPAP:

110826238

CIT:

102623084

CIC:	CICLE_v10033600mg

PVY:

116126439

MINC:

123212939 123217233

TCC:

18609713

GRA:	105764330 105791265

GHI:	107928685 107938267 107948771 121219416

GAB:	108469866 108479437

HSYR:

120199850 120203706

DZI:	111282492 111287576 111317979

EGR:

104415700

RARG:

115738870

GMX:	100777389 100810522

GSJ:	114370716 114377560

PVU:

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:

AIP:	107618070 107625794

AHF:	112711228 112777598

LANG:

109325639 109352426 109361052

PCIN:

129309434 129319658 129319659

QSA:	O6P43_025901

FVE:

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103403141 103423822

MSYL:

PXB:

PCOX:

ZJU:

MNT:

CSAV:

HLP:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:	110640467 110640481

MESC:

110628330

POP:

7477036

PEU:	105119896 105137484

PALZ:

118048804

PNZ:

133696542

JRE:	109003139 109019742

CILL:

CAVE:

AGLU:

QSU:

QLO:

CSAA:

TWL:	119991705 120000795

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

SVER:

CANN:

LBB:

NTA:	107771297 107795655 107814498 107826059

NSY:	104220819 104233502

NTO:	104103097 104108506

NAU:	109240871 109241021

INI:

109194042

ITR:

116027422

SIND:

105156691 105168390

OEU:	111378363 111398857

EGT:

105952651

SSPL:

121753754 121756853 121769374 121770083

SMIL:

SHIS:

APAN:

HPUM:

PHUA:

PEBU:

PTAB:

CARB:

HAN:	110878340 110911254 110912212

BHW:	143570833 143571763 143584530 143597290 143622330

ECAD:

122586825

LSV:	111883078 111913098

CCAV:

112513064 112515396

DCR:	108202753 108206655

AGRV:

141671724

CSIN:

114310333 114311457

RVL:	131309948 131310845

AEW:	130773026 130778529 130781777 130791081

DLT:

CFLO:

BVG:

SOE:

CQI:	110710625 110712581

ATRI:

130808209 130821807

SLAF:

141598565 141623595

MOF:

131153028

NNU:	104591674 104593279 104601489 104610889

MING:

122073913

TSS:	122670720 122670991

PSOM:

OSA:

DOSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119354402 119363699

TAES:

123044875 123052670 123188545

TUA:

HVG:

LPER:

LRD:

SBI:

ZMA:	100273176 100282384

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

TANG:

CROT:

144565007(CI51)

PDA:

103714475

EGU:	105037165 140851924

MUS:	103987388 103989915 135628012

ZOF:	122041960 122046484

DCT:

PEQ:

AOF:

MSIN:

ACAK:

NCOL:

ATR:	18422470 18429014

CJF:

131064625

SMO:	SELMODRAFT_150347 SELMODRAFT_443575

PPP:	112281950 112289393

CRE:	CHLRE_10g422600v5

VCN:	VOLCADRAFT_58014(nuo6)

MNG:

MNEG_8765

CSL:	COCSUDRAFT_22252

CVR:	CHLNCDRAFT_25226 CHLNCDRAFT_56910

APRO:

F751_1463

OLU:	OSTLU_43184

OTA:	OT_ostta15g00485

BPG:	Bathy02g02680

MIS:	MICPUN_94594

MPP:	MICPUCDRAFT_26689

CME:	CYME_CMJ185C

GSL:	Gasu_60740

CCP:	CHC_T00008807001

DHA:	DEHA2F08360g

PIC:	PICST_31688(NUO51)

PGU:	PGUG_01470 PGUG_01472

SPAA:

SPAPADRAFT_60356

LEL:	PVL30_001933(NDH51)

LBG:	92207655(LODBEIA_P24590)

CAL:	CAALFM_C204550CA(NDH51)

CTP:	CTRG_01603

COT:	CORT_0B05110

CDU:	CD36_19150(NDH51)

CTEN:

18249118(NDH51)

CLU:	CLUG_02615

CLUS:

A9F13_07g02541

CAUR:

CJI96_0001656

PPA:	PAS_chr2-2_0462

PKZ:	C5L36_0B00140

BNN:	FOA43_001028(NUO51)

BBRX:

BRETT_003676(NUO51)

OPA:	HPODL_04625

YLI:	2907626(YALI2_C00541g)

SLB:	AWJ20_1959

NCR:	NCU04044(nuo51)

NTE:	NEUTE1DRAFT69103(NEUTE1DRAFT_69103)

SMP:	10803199(SMAC4_07117)

PAN:	PODANSg3066

PBEL:

QC761_407950(NDH51)

PPSD:

QC762_407950(NDH51)

PPSP:

QC763_407950(NDH51)

PPSA:

QC764_407950(NDH51)

TTT:	THITE_2110073

MTM:	MYCTH_2306712

CTHR:

CTHT_0040970

RTHE:

98126776(VTJ83DRAFT_5522)

MGR:

MGG_00647

PPEI:

PpBr36_08505

PGRI:

PgNI_08671

TMN:	UCRPA7_1053

SSCK:

SPSK_00756

FGR:	FGSG_09250

FPU:	FPSE_09642

FPOA:

FPOAC1_012446(NUO51)

FVN:	FVRRES_13530

FVR:	FVEG_03859

FOX:	FOXG_05992

NHE:	NECHADRAFT_66841

FFC:	NCS54_00305900

FKR:	NCS57_00301300

FMU:	J7337_003869(NUO51)

TRE:	TRIREDRAFT_65559

TRR:	M419DRAFT_83693

TATV:

25778983(TrAtP1_001136)

TASP:

36607442(NUO51)

MAW:	19247707(NDH51_1)

MAJ:

MAA_01996

MBRN:

26239588(nuo-51)

PCHM:

VFPPC_13139

UVI:	66061431(UV8b_00653)

CMT:

CCM_00354

AMUS:

LMH87_000607

PLJ:	28886259(PLICBS_007743)

PTKZ:

JDV02_004399(NDH51)

DCON:

63714420(DCS_01777)

VAL:	VDBG_07885

VDA:	VDAG_05451

CFJ:	CFIO01_11854

CLUP:

CLUP02_00259

CHIG:

CH63R_08173

CDET:

87945412(CDEST_08909)

SAPO:

SAPIO_CDS9404

ELA:	UCREL1_1527

PFY:	PFICI_10108

SSL:	SS1G_11651

BFU:	BCIN_08g06780

MBE:

MBM_07021

PSCO:

LY89DRAFT_681275

GLZ:	GLAREA_04552

ANI:	ANIA_05629

AFM:	AFUA_4G11050

ACT:	ACLA_050150

NFI:	NFIA_104990

AOR:	AO090003001115

ANG:	An04g05640(nuo51)

AFV:	AFLA_000554

ALUC:

AKAW2_51535A(NDH51)

ACHE:

ACHE_10832S(NDH51)

APUU:

APUU_40997A(NDH51)

PCS:	N7525_005560

PDP:	PDIP_33370

POU:	POX_a01558

PPSF:

300795432(PFLUO_LOCUS9082)

TMF:	EYB26_005326

CIM:	CIMG_01512

CPW:	9691180(NDH51)

URE:	UREG_05077

ABE:

ARB_02297

TVE:

TRV_05072

PBL:	PAAG_02656

PBN:	PADG_01679

AJE:	HCAG_01603

BGH:	BDBG_03481

PNO:	SNOG_06231

PTE:

PTT_06938

PTRR:

6338639(PtrM4_019950)

BZE:	COCCADRAFT_85391

BSC:	COCSADRAFT_167314

BOR:	COCMIDRAFT_7292

AALT:

CC77DRAFT_1020472

ADAC:

96082165(ACET3X_001843)

ARAB:

EKO05_0005787

ZTR:	MYCGRDRAFT_99503

PFJ:	MYCFIDRAFT_59995

FFU:	CLAFUR5_05742

CBET:

CB0940_08548

BCOM:

BAUCODRAFT_32062

NPA:	UCRNP2_1627

TML:	GSTUM_00012037001

SPO:	2540740(SPOM_SPBC18E5.10)

SOM:	SOMG_02125

CNE:

CND04070

CNB:

CNBD2240

CNG:	CNAG_01287

CGI:	CGB_D7070W

CDEU:

CNBG_0855

CDEC:

89987018(IAS62_000242)

CTEG:

91987466(I308_100608)

CBAS:

91980294(I312_100246)

CDEP:

91090063(L203_105854)

KMG:	30163061(I203_102053)

KNE:	92180191(IAR55_002933)

KDJ:	28968925(I303_105327)

KBI:	30210275(I302_106859)

KPIN:

30170760(I206_104851)

KSH:	87957015(IL334_004884)

KER:	91101883(V865_003079)

KSN:	43585545(CI109_103053)

KBO:	90014806(L199_003822)

KEP:	91094095(L201_003425)

TMS:	TREMEDRAFT_45095

TASA:

A1Q1_01248

CCAC:

CcaHIS019_0310890(NDH51)

TVS:	TRAVEDRAFT_156371

DSQ:	DICSQDRAFT_93733

PCO:	PHACADRAFT_265636

SHS:	STEHIDRAFT_167184

HIR:	HETIRDRAFT_61275(nuor)

PSQ:	PUNSTDRAFT_49552

ADL:	AURDEDRAFT_175320

FME:	FOMMEDRAFT_119837

GTR:	GLOTRDRAFT_100387

RSX:	RhiXN_00192

LBC:	LACBIDRAFT_175119

CCI:	CC1G_03104

ABP:	AGABI1DRAFT116335(NdufV1)

ABV:	AGABI2DRAFT196262(NdufV1)

PCUB:

JR316_0006670

MPR:	MPER_06171

MRR:	Moror_6394

E1B28_007148(NUO51)

SCM:	SCHCO_02625175(SCHCODRAFT_02625175)

CPUT:

CONPUDRAFT_82497

SLA:	SERLADRAFT_469246(NdufV1)

WSE:	WALSEDRAFT_33799

WIC:	J056_000861

UMA:	UMAG_11170

PFP:	PFL1_03347

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_07805

PTRC:

PtA15_3A879

PSTR:

Pst134EA_006760

MLR:	MELLADRAFT_43743

RIE:	OCT59_014603

MBR:	MONBRDRAFT_32579

SRE:	PTSG_12376

DDI:	DDB_G0288875(ndufv1)

DPP:	DICPUDRAFT_158468

DFA:	DFA_06998(ndufv1)

ACAN:

ACA1_096330

TET:	TTHERM_00193910

PTM:	GSPATT00021369001 GSPATT00027584001 GSPATT00032834001 GSPATT00036838001

PTI:	PHATR_43944

FCY:	FRACYDRAFT_278067

TPS:	THAPSDRAFT_29850

AAF:	AURANDRAFT_24188(nuo1)

PIF:	PITG_06815

PSOJ:

PHYSODRAFT_350142

BLAC:

94345862(CCR75_002091)

SPAR:

SPRG_14893

TBR:	Tb927.5.450

TBG:	TbgDal_V450

TCR:	507869.10 508399.10

LMA:	LMJF_05_0980

LIF:	LINJ_05_0980

LDO:	LDBPK_050980

LMI:	LMXM_05_0980

LMAT:

92517644(LSCM1_07775)

LBZ:	LBRM_05_0980

LPAN:

LPMP_050980

LOI:	92363913(LSCM4_08103)

LEIS:

94183231(GH5_08013)

LENR:

94174825(CUR178_07675)

LEIN:

94191653(JIQ42_08086)

PHET:

94293441(JKF63_07425)

NGR:	NAEGRDRAFT_58165

TVA:	4767162(TVAGG3_0905620)

GTT:	GUITHDRAFT_198396

Reference

PMID:8288251

Authors

Ali ST, Duncan AM, Schappert K, Heng HH, Tsui LC, Chow W, Robinson BH

Title

Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13.

Journal

Genomics 18:435-9 (1993)
DOI:10.1006/geno.1993.1493

Sequence

[hsa:4723]

LinkDB

ORTHOLOGY: K03943

Entry

K03943                      KO

Symbol

NDUFV2

Name

NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map04932

Non-alcoholic fatty liver disease

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00143

NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria

Reaction

R11945

NADH:ubiquinone oxidoreductase

Disease

H00473

Mitochondrial complex I deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
  09159 Environmental adaptation
   04714 Thermogenesis
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
   05012 Parkinson disease
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
   05014 Amyotrophic lateral sclerosis
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
   05016 Huntington disease
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
   05020 Prion disease
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
   05022 Pathways of neurodegeneration - multiple diseases
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2
Enzymes [BR:ko01000]
7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2

Other DBs

GO:

TC:

139375784 139376514 139387270

Genes

HSA:	4729(NDUFV2)

PTR:	455295(NDUFV2)

PPS:	100985717(NDUFV2)

GGO:	101131474 101146734(NDUFV2)

PON:	100432094(NDUFV2)

PPYG:

129018915(NDUFV2)

NLE:	100600027(NDUFV2)

HMH:	116468740(NDUFV2)

SSYN:

129460486(NDUFV2)

MCC:	706067(NDUFV2)

MCF:	102122521 102124686(NDUFV2)

MTHB:

126930135 126941129

MNI:	105478880(NDUFV2)

CSAB:

103222752(NDUFV2)

CATY:

105579316(NDUFV2)

PANU:

100998941(NDUFV2)

TGE:	112611264(NDUFV2)

MLEU:

105542372(NDUFV2)

RRO:	104670231(NDUFV2) 104674738

RBB:	108525115(NDUFV2)

TFN:	117064141(NDUFV2)

PTEH:

111553523(NDUFV2)

CANG:

105507893(NDUFV2)

CJC:	100392484(NDUFV2)

SBQ:	101044354(NDUFV2)

CIMI:

108314835(NDUFV2)

ANAN:

105713201(NDUFV2)

CSYR:

103258337(NDUFV2)

MMUR:

105860911(NDUFV2)

LCAT:

123621509(NDUFV2)

ERUF:

138383392(NDUFV2)

PCOQ:

105813610(NDUFV2)

OGA:	100942143(NDUFV2)

MMU:	72900(Ndufv2)

MCAL:

110312153(Ndufv2)

MPAH:

110335628(Ndufv2)

RNO:	81728(Ndufv2)

MCOC:

116088857(Ndufv2)

ANU:	117693334(Ndufv2)

ASYL:

127692884(Ndufv2)

MUN:	110544152(Ndufv2)

CGE:	100757242(Ndufv2)

MAUA:

101825418(Ndufv2)

PROB:

127226765(Ndufv2)

PLEU:

114696316(Ndufv2)

PMAV:

102922457(Ndufv2)

MORG:

121433544(Ndufv2)

MFOT:

126507262 126508279

AAMP:

119821089(Ndufv2)

CNL:	130870482(Ndufv2)

NGI:	103735420 103740029 103743266

HGL:	101710102(Ndufv2)

CPOC:

100719197(Ndufv2)

CCAN:

109699960(Ndufv2)

DORD:

105985350 105985364 105999149 106001293(Ndufv2)

DSP:	122106236 122110984(Ndufv2)

DMER:

138828741 138832158(Ndufv2) 138832844

PLOP:

125364038(Ndufv2)

NCAR:

124965286

MMMA:

107139635(Ndufv2)

ITI:	101962428(Ndufv2)

OCU:

100358684

OPI:	101522189(NDUFV2)

OCZ:	121147405 121149930(NDUFV2)

TUP:	102468488 102468578(NDUFV2) 102469347

GVR:	103605247(NDUFV2) 103607466

CFA:	480204(NDUFV2)

CLUD:

112648058(NDUFV2)

VVP:	112925281(NDUFV2)

VLG:	121500930(NDUFV2)

NPO:	129508699(NDUFV2)

AML:	100465323(NDUFV2)

UMR:	103662415(NDUFV2)

UAH:	113253220(NDUFV2)

UAR:	123789911(NDUFV2)

ELK:

111142406

LLV:	125081923 125107912

MPUF:

101694351(NDUFV2)

MNP:	132023481(NDUFV2)

MLK:	131810801(NDUFV2)

NVS:	122903032(NDUFV2)

ORO:	101372239 101376526 101379479(NDUFV2) 101380104

EJU:	114207265 114224701(NDUFV2)

ZCA:	113912409(NDUFV2) 113914779 113920393

MLX:	118016431(NDUFV2)

MANO:

123852755(NDUFV2)

NSU:	110579816(NDUFV2)

LWW:	102741816(NDUFV2)

FCA:	101080579(NDUFV2)

PYU:	121033178(NDUFV2)

PCOO:

112868105(NDUFV2)

PBG:	122470566(NDUFV2)

PVIV:

125148899(NDUFV2)

LRUF:

124519802

LGF:	123587366(NDUFV2)

AJU:

106965538

PTG:	102966551(NDUFV2)

PPAD:

109248630(NDUFV2)

PUC:

125914817

PLEZ:

122204249(NDUFV2)

HHV:	120221592(NDUFV2)

CCRU:

144243186(NDUFV2)

BTA:	282290(NDUFV2)

BOM:	102276453(NDUFV2)

BIU:	109577897 109577904

BJV:	133237645(NDUFV2) 133249858

BBUB:

102391135(NDUFV2) 123329675 123465012

BKE:	129628675 129635882(NDUFV2)

BBIS:

104992940 105002486(NDUFV2)

CHX:	102176841(NDUFV2)

OAS:	101103690(NDUFV2)

OCAN:

138428212(NDUFV2)

BTAX:

128058489 128067418(NDUFV2)

CSUM:

138097449(NDUFV2)

ODA:	120881071(NDUFV2)

CCAD:

122421989 122425704(NDUFV2) 122439648

MREE:

136166405(NDUFV2)

OVR:	110127689(NDUFV2)

MBEZ:

129549785(NDUFV2)

SSC:	100037991(NDUFV2)

CFR:	102522489(NDUFV2)

CBAI:

105071425(NDUFV2)

CDK:	105086491(NDUFV2)

VPC:	102532562(NDUFV2)

BACU:

103018290(NDUFV2)

BMUS:

118906818(NDUFV2)

LVE:	103077470(NDUFV2)

OOR:	101274683(NDUFV2)

LALB:

132532124(NDUFV2)

GMF:	115842043(NDUFV2)

DDP:	132436143(NDUFV2)

DLE:	111162874(NDUFV2) 111172449

PCAD:

102992498(NDUFV2)

PSIU:

116738809(NDUFV2) 116753543

PPHC:

136132704(NDUFV2)

NASI:

112404308 112412202(NDUFV2)

ECB:	100054445(NDUFV2)

EPZ:	103554157(NDUFV2)

EAI:	106828659(NDUFV2)

MYB:	102260201(NDUFV2)

MYD:	102763208(NDUFV2)

MMYO:

118663528(NDUFV2)

MLF:	102423274(NDUFV2)

MDT:	132239776(NDUFV2)

MYUM:

139014018(NDUFV2)

PKL:	118707768(NDUFV2)

EFUS:

103302793(NDUFV2)

MNA:	107533978(NDUFV2)

DRO:	112322679(NDUFV2)

SHON:

118977219 118989984(NDUFV2)

AJM:	119047547(NDUFV2)

PDIC:

114506810(NDUFV2) 114510641

PHAS:

123826178(NDUFV2)

MMF:	118618922(NDUFV2)

PPAM:

129081681(NDUFV2)

HAI:	109386635(NDUFV2)

RFQ:	117011815(NDUFV2)

PALE:

102889596(NDUFV2)

PGIG:

120588577(NDUFV2)

PVP:	105296192(NDUFV2)

RAY:	107498174(NDUFV2)

MJV:	108404353(NDUFV2)

TOD:	119243186(NDUFV2)

SARA:

101558520(NDUFV2)

SFUM:

130045436(NDUFV2)

SETR:

126003788(NDUFV2)

LAV:	100673749(NDUFV2)

TMU:

101344328

ETF:	101648307(NDUFV2)

DNM:	101444678(NDUFV2)

MDO:	100016466(NDUFV2)

GAS:	123239561(NDUFV2)

SHR:	100928428(NDUFV2)

AFZ:

127544020

PCW:	110207769(NDUFV2)

TVP:	118845956(NDUFV2) 118857234

PBRV:

138170381(NDUFV2)

MLAO:

141498434(NDUFV2)

OAA:	100076572(NDUFV2)

TACU:

119928554(NDUFV2)

GGA:	426488(NDUFV2)

PCOC:

116226199(NDUFV2)

MGP:	100549664(NDUFV2)

CJO:	107310058(NDUFV2)

TPAI:

128090937(NDUFV2)

LMUT:

125690351(NDUFV2)

NMEL:

110393851(NDUFV2)

APLA:

101790841(NDUFV2)

AACU:

137850976(NDUFV2)

OJA:	118163214(NDUFV2)

ACYG:

106034937(NDUFV2)

CATA:

118256815(NDUFV2)

AFUL:

116485943 116486368(NDUFV2)

TGU:	100190350(NDUFV2)

LSR:	110467838(NDUFV2)

VMC:	128805910(NDUFV2)

VCHA:

128786246(NDUFV2)

AIB:	137475254(NDUFV2)

SCAN:

103826690(NDUFV2)

PMOA:

120500782(NDUFV2)

OTC:	121333161(NDUFV2)

PRUF:

121359009(NDUFV2)

ATRC:

139584904(NDUFV2)

MATE:

118699766(NDUFV2)

MAEN:

136563985(NDUFV2)

GFR:	102035061(NDUFV2)

FAB:	101811184(NDUFV2)

OMA:	130249159(NDUFV2)

PHI:	102106161(NDUFV2)

PMAJ:

107200564(NDUFV2)

CCAE:

111924968(NDUFV2)

CCW:	104687284(NDUFV2)

CBRC:

103612444(NDUFV2)

ACOE:

138104992(NDUFV2)

ETL:	114056671(NDUFV2)

ZAB:	102071004(NDUFV2)

ZLE:	135444351(NDUFV2)

ACHL:

103805283(NDUFV2)

SVG:	106850132(NDUFV2)

MMEA:

130575183(NDUFV2)

HRT:	120750861(NDUFV2)

SATI:

136367458(NDUFV2)

CFAI:

136289492(NDUFV2)

CCIC:

134041413(NDUFV2)

FPG:	101922896(NDUFV2)

FCH:	102050596(NDUFV2)

FRS:	119144226(NDUFV2)

CCRI:

104169043(NDUFV2)

NNT:	104400614(NDUFV2)

SHAB:

115609306(NDUFV2)

ACUN:

113476107(NDUFV2)

ANOC:

141957535(NDUFV2)

SURA:

141947357(NDUFV2)

TALA:

104366115(NDUFV2)

ACHC:

115340193(NDUFV2)

HALD:

104325439(NDUFV2)

HLE:	104842477(NDUFV2)

AGEN:

126051239

HHAR:

128142108(NDUFV2)

BBUT:

142028951(NDUFV2)

GCL:

127012908

CSTI:

104551489(NDUFV2)

LDI:	104351770(NDUFV2)

MNB:	103772263(NDUFV2)

DPUB:

104308707(NDUFV2)

PPUS:

135178864(NDUFV2)

IIN:	128967417(NDUFV2)

AVIT:

104268864(NDUFV2)

BRHI:

104500621(NDUFV2)

EGZ:	104132874(NDUFV2)

NNI:	104017666(NDUFV2)

PCRI:

104024830(NDUFV2)

PCAO:

104050180(NDUFV2)

PARX:

142053295(NDUFV2)

PADL:

103912343(NDUFV2)

AFOR:

103903011(NDUFV2)

FGA:	104071511(NDUFV2)

CBOR:

142078862(NDUFV2)

GSTE:

104263915(NDUFV2)

CBOY:

140647755(NDUFV2)

MAME:

142406035(NDUFV2)

CLV:	102086016(NDUFV2)

CNIC:

135985652(NDUFV2)

MUI:	104539273(NDUFV2)

PGUU:

104459574(NDUFV2)

PLET:

104621166(NDUFV2)

CMAC:

104486644(NDUFV2)

CUCA:

104065525(NDUFV2)

PCUR:

138719029(NDUFV2)

TEO:	104375794(NDUFV2)

BREG:

104632769(NDUFV2)

GAME:

129202035(NDUFV2)

OHA:	104326654(NDUFV2)

ACAR:

104518479(NDUFV2)

CPEA:

104397019(NDUFV2)

CVF:	104281924(NDUFV2)

RTD:	128904936(NDUFV2)

CRID:

134511883(NDUFV2)

LMIC:

141739430(NDUFV2)

NARQ:

141463706(NDUFV2)

AAM:	106484482(NDUFV2)

AROW:

112972369(NDUFV2)

NPD:	112954142(NDUFV2)

TGT:	104565100(NDUFV2)

DNE:	112979826(NDUFV2)

SCAM:

104139113(NDUFV2)

ASN:	102378613(NDUFV2)

AMJ:	102567061(NDUFV2)

CPOO:

109317402(NDUFV2)

GGN:	109303271(NDUFV2)

PSS:	102448470(NDUFV2)

CIZ:	142009405(NDUFV2)

CMY:	102941957(NDUFV2)

CCAY:

125632321(NDUFV2)

LKP:	140906835(NDUFV2)

NDS:	141982484(NDUFV2)

DCC:	119850960(NDUFV2)

CPIC:

101949523(NDUFV2)

TST:	117873355(NDUFV2)

EOB:	135873954(NDUFV2)

CABI:

116822909(NDUFV2)

MRV:	120397841(NDUFV2)

ACS:	100557190(ndufv2)

ASAO:

132774720(NDUFV2)

PVT:	110078900(NDUFV2)

SUND:

121928433(NDUFV2)

PBI:

103066080

PMUR:

107285984(NDUFV2)

CTIG:

120306268(NDUFV2)

TSR:	106553521(NDUFV2)

PGUT:

117672650(NDUFV2)

PCAE:

139314762(NDUFV2)

APRI:

131195956(NDUFV2)

PTEX:

113435511(NDUFV2)

NSS:	113414830(NDUFV2)

VKO:	123021629(NDUFV2)

PMUA:

114600742(NDUFV2)

PRAF:

128417611(NDUFV2)

ZVI:	118089855(NDUFV2)

HCG:	128322581(NDUFV2)

GJA:	107106462(NDUFV2)

STOW:

125438856(NDUFV2)

EMC:	129333210(NDUFV2)

XLA:	108719193(ndufv2.L)

XTR:	549920(ndufv2)

NPR:	108784591(NDUFV2)

RTEM:

120940875(NDUFV2)

ACAT:

141145065(NDUFV2) 141145925

PADS:

140330881(NDUFV2)

BBUF:

121001110(NDUFV2) 121003254

BGAR:

122939684(NDUFV2)

DTC:	141053841(NDUFV2)

HSQ:	130273970(NDUFV2)

PWL:	138267573(NDUFV2)

MUO:	115476792(NDUFV2)

GSH:	117355461(NDUFV2) 117355647

DRE:	393720(ndufv2)

SRX:	107750909 107754586

SANH:

107687898 107696125

SGH:	107569634 107596229

CCAR:

109062930 109109082

CAUA:

113045281 113112564

CGIB:

127937880 127951609

PTET:

122335702(ndufv2)

LROH:

127178965(ndufv2)

GRF:	141344385(ndufv2) 141344387

OMC:	131526235(ndufv2)

PPRM:

120461059(ndufv2)

RKG:	130105599(ndufv2)

MAMB:

125250372(ndufv2)

CIDE:

127507100

CERY:

137002817(ndufv2)

MASI:

127440690 127442527

TROS:

130554790(ndufv2)

TDW:	130418125(ndufv2)

MANU:

129443164 141351027

PDAB:

135744083(ndufv2)

IPU:	100528938(ndufv2)

IFU:	128623878(ndufv2)

PHYP:

113533265(ndufv2)

SMEO:

124403026(ndufv2)

TFD:	113645243(ndufv2)

TVC:	132846053(ndufv2)

CGAR:

128513225(ndufv2)

NGRA:

132871737(ndufv2)

TRN:	134302287(ndufv2)

AMEX:

103038922(ndufv2)

CMAO:

118797444(ndufv2)

EEE:	113581948(ndufv2)

CHAR:

105889533(ndufv2)

SPIL:

134066559(ndufv2)

ASAD:

121712348(ndufv2)

TRU:	101076909(ndufv2)

TFS:	130538390(ndufv2)

TNG:	GSTEN00027673G001

LCO:	104933686(ndufv2)

NCC:	104944916(ndufv2)

TBEN:

117500264(ndufv2)

CGOB:

115022904(ndufv2)

PGEO:

117462092(ndufv2)

GACU:

117540867(ndufv2)

EMAC:

134865933(ndufv2)

ELY:	117271900(ndufv2)

EFO:	125901949(ndufv2)

PLEP:

121951645(ndufv2)

SLUC:

116045843(ndufv2)

SVIT:

144526716(ndufv2)

ECRA:

117953708(ndufv2)

ESP:	116699419(ndufv2)

PFLV:

114565373(ndufv2)

PFLT:

120568362(ndufv2)

GAT:	120815663(ndufv2)

PPUG:

119202837(ndufv2)

AFB:	129089366(ndufv2)

CLUM:

117746149(ndufv2)

PSWI:

130197785(ndufv2)

CANA:

137782347(ndufv2)

CVE:	137866096(ndufv2)

AMIR:

142956365(ndufv2)

MSAM:

119901815(ndufv2)

SCHU:

122887363(ndufv2)

EARM:

139296299(ndufv2)

CUD:	121520003(ndufv2)

SPUL:

138611374(ndufv2)

LMIX:

132979414(ndufv2)

HTC:	141804821(ndufv2)

ALAT:

119011850(ndufv2)

ASTR:

137612022(ndufv2)

PKLU:

139214781(ndufv2)

MZE:	101484885(ndufv2)

ONL:	100697524(ndufv2)

OAU:	116313372(ndufv2)

OLA:	101172359(ndufv2)

OML:	112151897(ndufv2)

CSAI:

133452456(ndufv2)

XMA:	102225881(ndufv2)

XCO:	114146867(ndufv2)

XHE:	116722207(ndufv2)

PRET:

103479727(ndufv2)

PFOR:

103146320(ndufv2)

PLAI:

106957666(ndufv2)

PMEI:

106921610(ndufv2)

GAF:	122840876(ndufv2)

PPRL:

129378037(ndufv2)

CVG:	107089441(ndufv2)

CTUL:

119787184(ndufv2)

GMU:	124869949(ndufv2)

NFU:	107383542(ndufv2)

KMR:	108232989(ndufv2)

ALIM:

106525791(ndufv2)

NWH:	119415224(ndufv2)

AOCE:

111570826(ndufv2)

EJA:	138203196(ndufv2)

BFRE:

138617459(ndufv2)

MCEP:

125010307(ndufv2)

CSEM:

103396536(ndufv2)

POV:	109637418(ndufv2)

SSEN:

122780069(ndufv2)

SSOE:

131467564(ndufv2)

HHIP:

117777658(ndufv2)

HSP:	118118279(ndufv2)

PPLT:

128454303(ndufv2)

SMAU:

118311707(ndufv2)

LCF:

108884238

SDU:	111230969(ndufv2)

SLAL:

111658395(ndufv2)

XGL:	120799485(ndufv2)

HCQ:	109529476(ndufv2)

SSCV:

125985247(ndufv2)

SBIA:

133510550(ndufv2)

PEE:	133412081(ndufv2)

PTAO:

133489527(ndufv2)

BPEC:

110174898

ENY:	140356007(ndufv2)

MALB:

109955291(ndufv2)

BSPL:

114844013(ndufv2)

SJO:	128369234(ndufv2)

SSCO:

133990934(ndufv2)

TTY:	137194484(ndufv2)

GMH:	115548337(ndufv2)

SASA:

106592348(ndufv2)

STRU:

115157606(ndufv2)

OTW:

112227960

OMY:	110509146(ndufv2) 110530857

OGO:

124010171

ONE:	115124239(ndufv2)

OKI:	109880791 109881558

OKE:	118402465(ndufv2)

OMM:	135509004 135529992 135534244 135558329

OCLA:

SALP:

112074795 112076291

SNH:	120041304 120043296

SFON:

129813337 129823555

CCLU:

121535711(ndufv2)

ELS:	105025324(ndufv2)

OEP:	134036292(ndufv2)

SFM:	108930064(ndufv2)

PKI:	111851394(ndufv2)

AANG:

118226401(ndufv2)

AROT:

135252727(ndufv2)

CCOG:

133127365(ndufv2)

LOC:	102683869(ndufv2)

PSPA:

121313532(ndufv2)

ARUT:

117400508 117435575

PSEX:

120530351(ndufv2)

LCM:	102353054(NDUFV2)

CMK:	103181050(ndufv2)

RTP:	109932208(ndufv2)

CPLA:

122548877(ndufv2)

CPUN:

140476927(ndufv2)

HOC:	132815093(ndufv2)

SCAU:

119972274(ndufv2)

LERI:

129696238(ndufv2)

HAKA:

140728522(ndufv2)

PMRN:

116955470(NDUFV2)

LRJ:	133356912(NDUFV2)

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG5703(ND-24) Dmel_CG6485(ND-24L)

DER:	6543663 6550191

DSE:	6606063 6618099

DSI:	Dsimw501_GD12420(Dsim_GD12420) Dsimw501_GD15675(Dsim_GD15675)

DYA:	Dyak_GE17674 Dyak_GE22166

DAN:

6505054

DSR:

110176119

DPO:	4813299 4814923

DPE:	6598155 6601415

DMN:	108150799 108164388

DWI:

6648705

DGR:	6557603 6565828

DMO:	Dmoj_GI12897 Dmoj_GI14890

DAZ:	108612682 108619533

DNV:	108652343 115565127

DHE:	111601828 111605186

DVI:	6635465(ND-24)

CCAT:

101454655

BOD:	106616716(ND-24)

BDR:

105222868

RZE:	108356200 108375663 108376025

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135956666(ND-24)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ANIL:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ018666 CpipJ_CPIJ018667

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

APUR:

144467884(Nd-24)

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108723845(ND-24)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139101729(Nd-24)

TLN:	139812302(Nd-24)

TAME:

143898699(Nd-24)

TNY:	139768995(Nd-24)

HST:

DQU:

CFO:

FEX:

PMEC:

138938085(Nd-24)

LHU:	105677478(ND-24)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100115243(Ndufv2)

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141536147(Nd-24)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124210705(ND-24)

NFB:

NLO:

NVG:

AROA:

TCA:	657790(Ndufv2)

TMOL:

138140430(ND-24)

DPA:

109538865

ESIM:

136411872(ND-24)

EFOR:

136349417(ND-24)

SOY:

115880362

RFG:	143204270(ND-24)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203718 KGM_212938

BANY:

112053589 112056078

MJU:	123868175 123869853

NIQ:	126774339 126781661

VCD:	124536539 124542531

MCIX:

123653799 123659575

PMAC:

106710446 106717585

PPOT:

106100541 106109711

PXU:	106121044 106124183

BPHI:

137919266(ND-24) 137926697

PRAP:

110992159 110995794

PBX:	123715599 123716318

PNAP:

125053070 125057042

ZCE:	119829346 119840644

CCRC:

123694240 123696066

LSIN:

126966420 126976835 126976836 126976837

AAGE:

121738483

HAW:	110375851 126056980

HZE:	124632453 124635037

TNL:	113496875 113497892 113498134

SLIU:

111352992 111359096

OFU:	114349852 114366639

ONU:	135075830 135077696

ATRA:

106133432 106137794

GMW:

113521238

ECLR:

140752339 140756038(ND-24)

PXY:	105391531 105392372

PGW:	126372551 126375510

LGLY:

125225380 125231846

CSTB:

134745639 134756208

CFUM:

141430164(ND-24) 141437614

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106679566(ND-24)

NLU:

111048919

LDA:	142325942(ND-24)

MQU:

129002595

PHU:	Phum_PHUM140110

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138713651(ND-24)

SGRE:

126355170

BROR:

134542614

IEL:

124164521

HAMR:

139687180(ND-24)

FCD:

110851824

DPX:	DAPPUDRAFT_231246

DMK:

116916535

DPZ:

124328248

AFRA:

136033205

PVM:	113823591(ND-24)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123756353(ND-24)

CQD:	128694754(ND-24)

PTRU:

SPRM:

ESN:

MNZ:

MRJ:	136842862(ND-24)

PORN:

139746511(ND-24)

HAZT:

108676086

OOT:	143021906(ND-24)

EAF:

111701315

LSM:	121120204(ND-24)

TCF:

131893079

PPOI:

119106299

DSV:

119464339

DALB:

139050562(ND-24)

RSAN:

119401354

RMP:	119164017(ND-24)

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136969558(ND-24)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F53F4.10(nduv-2)

CBR:

CBG_11518

CRQ:	GCK72_018617

NAI:	NECAME_08110

BMY:	BM_BM4310(Bm4310)

LOA:	LOAG_05848

TSP:

Tsp_12317

HRO:	HELRODRAFT_157926

LGI:	LOTGIDRAFT_211364

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106180415 106181716

SMM:	Smp_069770

SHX:	MS3_00009127(NDUFV2_1)

OVI:	T265_07698

EGL:

EGR_05605

LLON:

135495670

NVE:

5518100

EPA:	110233429 110244592

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_24589

AQU:

CCLM:

ATH:

ALY:

CRB:	17882494 17882858

CSAT:

104707837 104714255 104737507

EUS:	EUTSA_v10028900mg

BRP:	103836732 103858755

BNA:	106388601 106432387 106438704 106439321

BOE:	106318668 106320713 106323946

RSZ:	108828046 108833208 108847116

THJ:	104801256 104825981

CPAP:

110814807

CIT:

102608138

CIC:	CICLE_v10021811mg

PVY:

116128351

MINC:

123212563 123222399

TCC:

18613239

GRA:	105766628 105790482

GHI:	107916425 107941650 107955474 107961044

GAB:	108467496 108487156

HSYR:

120129651 120136844 120172459 120189149

DZI:	111283282 111305247 111314280

EGR:

104426622

RARG:

115752071

GMX:	100306106 100786050

GSJ:	114372887 114388729

PVU:

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

127080143 127087595 127095400 127115542

VVO:

LJA:

ADU:

AIP:

AHF:	112706328 112765192

LANG:

109342799 109351160

PCIN:

129290485

QSA:	O6P43_017991 O6P43_027906

FVE:

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103436073 103436074

MSYL:

126611609 126611610

PXB:	103928926 103928927 103928942 103928943 103930848 103930849

PCOX:

137749256 137749257

ZJU:	107417729 107417731

MNT:

CSAV:

HLP:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:	110659662 110665447

MESC:

110611346 110630740

POP:	7472002 7476882

PEU:	105126782 105138120

PALZ:

118049300 118061702

PNZ:	133690602 133694493

JRE:	108988509 108998150

CILL:

CAVE:

AGLU:

QSU:

QLO:

CSAA:

TWL:	119990549 120007072

VVI:

100242595

VRI:	117905496 117918267

SLY:

SPEN:

SOT:

SSTN:

SDUL:

SVER:

CANN:

LBB:

NTA:	107819175 107824942

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

121755513 121762965 121764002 121767057 121790922

SHIS:

APAN:

HPUM:

PHUA:

PEBU:

PTAB:

CARB:

HAN:	110865330 110910325

BHW:	143532559 143565787 143566168 143591638 143602107 143637460

ECAD:

LSV:

CCAV:

DCR:

AGRV:

CSIN:

RVL:

AEW:	130751755 130770411

DLT:

CFLO:

BVG:

SOE:

CQI:	110728950 110734419

ATRI:

130798566

SLAF:

141652521 141653051

MOF:

131155040

NNU:	104589639 104609560

MING:

122061354 122091839

TSS:	122642538 122662400

PSOM:

OSA:

DOSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119286133 119348923

TAES:

123061985 123139359 123182563

TUA:

HVG:

LPER:

LRD:

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

TANG:

CROT:

PDA:

EGU:

MUS:	103982986 135616842

ZOF:	121992041 121995961

DCT:

110110469

PEQ:

110023540

AOF:	109820541 109834504

MSIN:

ACAK:

NCOL:

ATR:

CJF:	131030991 131044498

SMO:	SELMODRAFT_165405 SELMODRAFT_83866

PPP:	112278814 112290975

CRE:	CHLRE_10g450400v5

VCN:	VOLCADRAFT_120415(nuo5)

MNG:	MNEG_10456

CSL:	COCSUDRAFT_18421

CVR:	CHLNCDRAFT_34626

APRO:

F751_6426

OLU:	OSTLU_7050

OTA:	OT_ostta20g00420

BPG:	Bathy15g00470

MIS:	MICPUN_85881

MPP:	MICPUCDRAFT_21836

CME:	CYME_CMR188C

GSL:	Gasu_14530

CCP:	CHC_T00009333001

DHA:	DEHA2A06820g

PIC:	PICST_76559(NUO24)

PGU:	PGUG_02076

SPAA:

SPAPADRAFT_60931

LEL:	PVL30_001173(NUO24)

LBG:	92209724(LODBEIA_P45280)

CAL:	CAALFM_C200400CA(CaO19.2091)

CTP:	CTRG_01110

COT:	CORT_0A12700

CDU:	CD36_15370(NUO24)

CTEN:

18247779(NUO24)

CLU:	CLUG_00786

CLUS:

A9F13_10g00484

CAUR:

CJI96_0000111

ASAU:

88176105(PUMCH_005046)

PPA:	PAS_chr2-1_0359

PKZ:	C5L36_0B06150

BNN:	FOA43_003341

BBRX:

BRETT_004187

OPA:	HPODL_01287

YLI:	2910293(YALI2_D01109g)

SLB:

AWJ20_976

NCR:	NCU01169(nuo24)

NTE:	NEUTE1DRAFT144245(NEUTE1DRAFT_144245)

SMP:	10807142(SMAC4_03237)

PAN:	PODANSg7956

PBEL:

QC761_201690(NUO24)

PPSD:

QC762_201690(NUO24)

PPSP:

QC763_201690(NUO24)

PPSA:

QC764_201690(NUO24)

TTT:	THITE_2106558

MTM:	MYCTH_2300433

CTHR:

CTHT_0052320

RTHE:

98128797(VTJ83DRAFT_7341)

MGR:

MGG_07301

PPEI:

PpBr36_01944

PGRI:

PgNI_07728

TMN:	UCRPA7_5175

SSCK:

SPSK_09478

FGR:	FGSG_10231

FPU:	FPSE_03642

FPOA:

FPOAC1_003328(NUO24)

FVN:	FVRRES_03672

FVR:	FVEG_02986

FOX:	FOXG_05147

NHE:	NECHADRAFT_61324

FFC:	NCS54_00714800

FKR:	NCS57_00754900

FMU:	J7337_005891(NUO24)

TRE:	TRIREDRAFT_5387

TRR:	M419DRAFT_88178

TATV:

25782468(TrAtP1_006847)

TASP:

36618198(NUO24)

MAW:	19246881(NUO24_1)

MAJ:

MAA_03070

MBRN:

26241436(nuo-24)

PCHM:

VFPPC_09550

UVI:	66060909(UV8b_00131)

CMT:

CCM_00285

AMUS:

LMH87_000523

PLJ:	28886723(PLICBS_002050)

PTKZ:

JDV02_006879(NUO24)

DCON:

63714269(DCS_01626)

VAL:	VDBG_00354

VDA:	VDAG_08648

CFJ:	CFIO01_13159

CLUP:

CLUP02_10697

CHIG:

CH63R_09005

CDET:

87950189(CDEST_13689)

SAPO:

SAPIO_CDS10695

ELA:	UCREL1_8061

PFY:	PFICI_07110

SSL:	SS1G_04889

BFU:	BCIN_09g00540

MBE:

MBM_08900

PSCO:

LY89DRAFT_618533

GLZ:	GLAREA_04381

ANI:	ANIA_06077

AFM:	AFUA_2G09130

ACT:	ACLA_080940

NFI:	NFIA_084660

AOR:	AO090011000782

ANG:	An12g04780

AFV:	AFLA_008177

ALUC:

AKAW2_60872A(NUO24)

ACHE:

ACHE_50456S(NUO24)

APUU:

APUU_11168A(NUO24)

PCS:	N7525_010700

PDP:	PDIP_19660

POU:	POX_f08424

PPSF:

300795921(PFLUO_LOCUS9522)

TMF:	EYB26_001365

TRG:	TRUGW13939_06028

CIM:	CIMG_01025

CPW:	9691580(NUO24)

URE:	UREG_00971

ABE:

ARB_05044

TVE:

TRV_01455

PBL:	PAAG_01044

PBN:	PADG_03786

AJE:	HCAG_03687

BGH:	BDBG_05463

PNO:	SNOG_03113

PTE:

PTT_07946

PTRR:

6350013(PtrM4_030860)

BZE:	COCCADRAFT_104724

BSC:	COCSADRAFT_24610

BOR:	COCMIDRAFT_79313

AALT:

CC77DRAFT_1023792

ADAC:

96088002(ACET3X_007680)

ARAB:

EKO05_0000606

ZTR:	MYCGRDRAFT_73335

PFJ:	MYCFIDRAFT_165834

FFU:	CLAFUR5_09739

CBET:

CB0940_10589

BCOM:

BAUCODRAFT_498931

NPA:	UCRNP2_7288

TML:	GSTUM_00005552001

SPO:	2542955(SPOM_SPAC11E3.12)

SOM:	SOMG_04019

CNE:

CNC07090

CNB:

CNBC0100

CNG:	CNAG_01470

CGI:	CGB_C0120C

CDEU:

CNBG_3958

CDEC:

89988337(IAS62_001562)

CTEG:

91988510(I308_101652)

CBAS:

91981700(I312_101652)

CDEP:

91090144(L203_105936)

KMG:	30165281(I203_101414)

KNE:	92179714(IAR55_002456)

KDJ:	28966663(I303_102945)

KBI:	30205280(I302_102193)

KPIN:

30171222(I206_102502)

KSH:	87954837(IL334_002706)

KER:	91102562(V865_003759)

KSN:	43591420(CI109_100876)

KBO:	90014117(L199_003132)

KEP:	91093529(L201_002858)

TMS:	TREMEDRAFT_68856

TASA:

A1Q1_04012

CCAC:

CcaHIS019_0508860(NUO24)

TVS:	TRAVEDRAFT_120720

DSQ:	DICSQDRAFT_146230

PCO:	PHACADRAFT_184607

SHS:	STEHIDRAFT_166582

HIR:	HETIRDRAFT_414468

PSQ:	PUNSTDRAFT_104301

ADL:	AURDEDRAFT_180503

FME:	FOMMEDRAFT_110953

GTR:	GLOTRDRAFT_36438

RSX:	RhiXN_01890

LBC:	LACBIDRAFT_306196

CCI:	CC1G_03815

ABP:	AGABI1DRAFT82650(NdufV2)

ABV:	AGABI2DRAFT134160(NdufV2)

PCUB:

JR316_0003241

MRR:	Moror_8897

E1B28_008624(NUO24)

SCM:	SCHCO_02624679(SCHCODRAFT_02624679)

CPUT:

CONPUDRAFT_98117

SLA:	SERLADRAFT_473939(NdufV2)

WSE:	WALSEDRAFT_44872

WIC:	J056_003179

UMA:	UMAG_00634

PFP:	PFL1_00575

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_19779

PTRC:

PtA15_9A434

PSTR:

Pst134EA_013318 Pst134EA_013350

MLR:	MELLADRAFT_71096

RIE:	OCT59_025709

MBR:	MONBRDRAFT_38648

SRE:	PTSG_08639

DDI:	DDB_G0291173(ndufv2)

DPP:	DICPUDRAFT_57306

DFA:	DFA_02220(ndufv2)

ACAN:

ACA1_292780

TET:	TTHERM_00335630

PTM:	GSPATT00000259001 GSPATT00000852001 GSPATT00003580001 GSPATT00008679001 PTMB.256c

PTI:	PHATRDRAFT_22919

FCY:	FRACYDRAFT_273772

TPS:	THAPSDRAFT_26002

AAF:	AURANDRAFT_59800

PIF:	PITG_13683

PSOJ:

PHYSODRAFT_566176

BLAC:

94344634(CCR75_000857)

SPAR:

SPRG_01020

TBR:	Tb927.7.6350

TBG:	TbgDal_VII7330

TCR:	506513.190 511323.50

LMA:	LMJF_17_0270

LIF:	LINJ_17_0320

LDO:	LDBPK_170320

LMI:	LMXM_17_0270

LMAT:

92515472(LSCM1_05505)

LBZ:	LBRM_17_0250

LPAN:

LPMP_170230

LOI:	92362715(LSCM4_06870)

LEIS:

94182024(GH5_06737)

LENR:

94173180(CUR178_05993)

LEIN:

94190870(JIQ42_07282)

PHET:

94291451(JKF63_05414)

NGR:	NAEGRDRAFT_69707

TVA:	4757044(TVAGG3_0162180)

EHX:	EMIHUDRAFT_417860

GTT:	GUITHDRAFT_151242

REN:	EF513_05580(nuoE)

CAQ:	IM40_07280

NAF:	GQ61_00880

KEU:	S101446_01323

KSC:	CD178_02022(nqo2)

AACE:

A0U92_11170

AZL:	AZL_021440(nuoE)

ALI:	AZOLI_2202(nuoE)

ABS:	AZOBR_100247(nuoE)

ABQ:	ABAZ39_08370

ABF:	AMK58_06130

ATI:	AL072_08205

AHU:	A6A40_08575

AZT:	TSH58p_05895

AZM:	DM194_08015

AZZ:	DEW08_00040

AOZ:	HUE56_13920(nuoE)

AARE:

D3093_01110(nuoE)

AZS:	E6C72_00670(nuoE)

AZP:	E6C67_23925(nuoE)

ADJ:	ACIU1J_19185(nuoE)

TXI:

TH3_10615

THAC:

CSC3H3_10315

TII:	DY252_13475(nuoE)

MAGQ:

MGMAQ_1977(nuoE)

HOH:

Hoch_1924

MAI:

MICA_1366

MAN:

A11S_1296

THYD:

TTHT_1261(nuoE)

GAU:	GAU_1658(nuoE)

GBA:

J421_3291

DIN:	Selin_0887

NMV:	NITMOv2_0540(nuoE)

PCAY:

FRD00_00140

CCZ:	CCALI_01774

Reference

PMID:2500970

Authors

Pilkington SJ, Walker JE

Title

Mitochondrial NADH-ubiquinone reductase: complementary DNA sequences of import precursors of the bovine and human 24-kDa subunit.

Journal

Biochemistry 28:3257-64 (1989)
DOI:10.1021/bi00450a031

Sequence

[hsa:4729]

LinkDB

ORTHOLOGY: K03944

Entry

K03944                      KO

Symbol

NDUFV3

Name

NADH dehydrogenase (ubiquinone) flavoprotein 3

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map04932

Non-alcoholic fatty liver disease

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00143

NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
  09159 Environmental adaptation
   04714 Thermogenesis
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
   05012 Parkinson disease
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
   05014 Amyotrophic lateral sclerosis
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
   05016 Huntington disease
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
   05020 Prion disease
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
   05022 Pathways of neurodegeneration - multiple diseases
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3

Other DBs

TC:

Genes

HSA:	4731(NDUFV3)

PTR:	736470(NDUFV3)

PPS:	100976506(NDUFV3)

GGO:	101147133(NDUFV3)

PON:	100458281(NDUFV3)

PPYG:

129022316(NDUFV3)

NLE:	100596062(NDUFV3)

HMH:	116481681(NDUFV3)

SSYN:

129483035(NDUFV3)

MCC:	722400(NDUFV3)

MCF:	102117222(NDUFV3)

MTHB:

126950655

MNI:	105472574(NDUFV3)

CSAB:

103219478(NDUFV3)

CATY:

105575491(NDUFV3)

PANU:

101009040(NDUFV3)

TGE:	112621241(NDUFV3)

MLEU:

105555594(NDUFV3)

RRO:	104678001(NDUFV3)

RBB:	108517346(NDUFV3)

TFN:	117095835(NDUFV3)

PTEH:

111527268(NDUFV3) 111534400

CANG:

105520391(NDUFV3)

CJC:	100413893(NDUFV3)

SBQ:	101035145(NDUFV3)

CIMI:

108311216(NDUFV3)

ANAN:

105711996(NDUFV3)

CSYR:

103272691(NDUFV3)

MMUR:

105879121(NDUFV3)

LCAT:

123630777(NDUFV3)

ERUF:

138386062(NDUFV3)

PCOQ:

105822913(NDUFV3)

OGA:	100966177(NDUFV3)

MMU:	78330(Ndufv3)

MCAL:

110283628(Ndufv3)

MPAH:

110338235(Ndufv3)

RNO:	64539(Ndufv3)

MCOC:

116075130(Ndufv3)

ANU:	117724927(Ndufv3)

ASYL:

127669591(Ndufv3)

MUN:	110553314(Ndufv3) 110554348

CGE:	100761076(Ndufv3)

MAUA:

101826784(Ndufv3)

PROB:

127224173(Ndufv3)

PLEU:

114703694 114703999(Ndufv3)

MORG:

121435615(Ndufv3) 121441232 121441356

MFOT:

126499007

AAMP:

119823492(Ndufv3)

NGI:	103729334(Ndufv3)

HGL:	101706205(Ndufv3)

CPOC:

100734603(Ndufv3)

CCAN:

109676035(Ndufv3)

DORD:

105993991(Ndufv3)

DSP:	122114211(Ndufv3)

DMER:

138832593(Ndufv3)

PLOP:

125351428(Ndufv3)

NCAR:

124993284

MMMA:

107136511(Ndufv3)

ITI:	101967848(Ndufv3)

OCU:

103346740

OCZ:	121160677(NDUFV3)

TUP:	102467780(NDUFV3)

GVR:	103581319(NDUFV3)

CFA:	478421(NDUFV3)

CLUD:

112669177(NDUFV3)

VVP:	112908003(NDUFV3) 112921285

VLG:	121479502(NDUFV3)

NPO:	129496000 129502163(NDUFV3)

AML:	100469433(NDUFV3)

UMR:	103680708(NDUFV3)

UAH:	113254594(NDUFV3)

UAR:	123777477(NDUFV3)

ELK:

111155738

LLV:

125093717

MPUF:

101679801(NDUFV3)

MNP:	132012433(NDUFV3)

MLK:	131825420(NDUFV3)

NVS:	122908267(NDUFV3)

ORO:	101363344(NDUFV3)

EJU:	114226430(NDUFV3)

ZCA:	113918208(NDUFV3) 113928501

MLX:	118026972(NDUFV3)

MANO:

123863159(NDUFV3)

NSU:	110571047(NDUFV3)

LWW:	102739777 102750788

FCA:	101084817(NDUFV3)

PYU:	121035897(NDUFV3)

PCOO:

112850447(NDUFV3)

PBG:	122491130(NDUFV3)

PVIV:

125159132(NDUFV3)

LRUF:

124526774

LGF:	123610521(NDUFV3)

AJU:

106985643

PTG:	102965900(NDUFV3)

PPAD:

109256940(NDUFV3)

PUC:

125920691

PLEZ:

122230325(NDUFV3)

HHV:	120240692(NDUFV3)

BTA:	327717(NDUFV3)

BOM:	102285119(NDUFV3)

BIU:	109560673(NDUFV3)

BBUB:

102392551(NDUFV3)

BBIS:

104984944(NDUFV3)

CHX:	102183643(NDUFV3)

OAS:	101105620(NDUFV3)

BTAX:

128045118(NDUFV3)

CSUM:

138081748(NDUFV3)

ODA:	120883165(NDUFV3)

CCAD:

122445384(NDUFV3)

MREE:

136173219(NDUFV3)

OVR:	110136804(NDUFV3)

MBEZ:

129548146(NDUFV3)

SSC:	100620809(NDUFV3)

CFR:	102510141 102521191(NDUFV3)

CBAI:

105078031(NDUFV3) 105082010

CDK:	105091110 105105846(NDUFV3)

VPC:	102533334(NDUFV3) 116277286

BACU:

103020190(NDUFV3)

BMUS:

118889521 118894426(NDUFV3)

LVE:	103082014(NDUFV3)

OOR:	101280712(NDUFV3)

LALB:

132521360(NDUFV3)

GMF:	115841516(NDUFV3)

DDP:	132424531(NDUFV3)

DLE:	111163814(NDUFV3)

PCAD:

102977740 102980571(NDUFV3)

PSIU:

116753303(NDUFV3)

PPHC:

136122736(NDUFV3)

NASI:

112408591(NDUFV3)

ECB:	100057691(NDUFV3)

EPZ:	103543621(NDUFV3)

EAI:	106829925(NDUFV3)

MYB:	102256583(NDUFV3)

MYD:	102771385(NDUFV3)

MMYO:

118676864(NDUFV3)

MLF:	102429252(NDUFV3)

MDT:	132229676 132229920(NDUFV3)

MYUM:

139004257(NDUFV3)

PKL:	118723898(NDUFV3)

EFUS:

103289795(NDUFV3) 103294284

MNA:	107541255(NDUFV3)

DRO:	112306093(NDUFV3)

SHON:

118984862(NDUFV3)

AJM:	119048802(NDUFV3)

PDIC:

114490883(NDUFV3)

PHAS:

123828050(NDUFV3)

MMF:	118617761(NDUFV3) 118624749

PPAM:

129074799(NDUFV3)

HAI:	109395199(NDUFV3) 109396584

RFQ:	117037775(NDUFV3)

PALE:

102879948 102892936(NDUFV3)

PGIG:

120598742(NDUFV3) 120613848

PVP:	105305394(NDUFV3) 111742157

RAY:	107510187(NDUFV3)

MJV:	108392420(NDUFV3)

TOD:	119257171(NDUFV3)

SARA:

101540968(NDUFV3)

SFUM:

130028732(NDUFV3)

SETR:

126025659(NDUFV3)

LAV:	100670560(NDUFV3)

TMU:

101352739

ETF:	101649115(NDUFV3)

DNM:	101422946(NDUFV3)

MDO:	103103819(NDUFV3)

GAS:	123239614(NDUFV3)

SHR:	100919401 100919666

AFZ:

127553793

PCW:	110199159(NDUFV3)

TVP:	118838494(NDUFV3)

PBRV:

138151375(NDUFV3)

OAA:	100080859(NDUFV3)

TACU:

119940155(NDUFV3)

GGA:	418541(NDUFV3)

PCOC:

116229889(NDUFV3)

MGP:	100550118(NDUFV3)

CJO:	107323888(NDUFV3)

TPAI:

128076497(NDUFV3)

LMUT:

125687852(NDUFV3)

NMEL:

110403403(NDUFV3)

APLA:

101800853(NDUFV3)

AACU:

137857898(NDUFV3)

ACYG:

106036100(NDUFV3)

AFUL:

116498386(NDUFV3)

TGU:	100231827(NDUFV3)

LSR:	110479439(NDUFV3)

SCAN:

103815888(NDUFV3)

PMOA:

120511795(NDUFV3)

OTC:	121333472(NDUFV3)

PRUF:

121364508(NDUFV3)

ATRC:

139591541(NDUFV3)

GFR:	102034473(NDUFV3)

FAB:	101818489(NDUFV3)

OMA:	130260234(NDUFV3)

PHI:	102108403(NDUFV3)

PMAJ:

107211269(NDUFV3)

CCAE:

111927557(NDUFV3) 111942223

CCW:	104686260(NDUFV3)

CBRC:

103614847(NDUFV3)

ACOE:

138112652(NDUFV3)

ZAB:	106629489(NDUFV3)

ZLE:	135444360(NDUFV3)

ACHL:

103798617(NDUFV3)

SVG:	106853483(NDUFV3)

MMEA:

130583387(NDUFV3)

HRT:	120749418(NDUFV3)

SATI:

136358191(NDUFV3)

CCIC:

134041405(NDUFV3)

FPG:	101911726(NDUFV3)

FCH:	102049063(NDUFV3)

CCRI:

104155756(NDUFV3)

NNT:	104409517(NDUFV3)

SHAB:

115603662(NDUFV3)

ACUN:

113481919(NDUFV3)

TALA:

104357043(NDUFV3)

HALD:

104315957(NDUFV3)

HLE:	104839781(NDUFV3)

AGEN:

126053267

HHAR:

128144699(NDUFV3)

BBUT:

142033603(NDUFV3)

GCL:

127026388

CSTI:

104559650(NDUFV3)

LDI:	104341689(NDUFV3)

MNB:	103781794(NDUFV3)

DPUB:

104305035(NDUFV3)

PPUS:

135180224(NDUFV3)

AVIT:

104269358(NDUFV3)

BRHI:

104488294(NDUFV3)

EGZ:	104128195(NDUFV3)

PCRI:

104036598(NDUFV3)

PCAO:

104041135(NDUFV3)

PARX:

142059881(NDUFV3)

PADL:

103920299(NDUFV3)

AFOR:

103902015(NDUFV3)

FGA:	104072533(NDUFV3)

CBOR:

142092765(NDUFV3)

GSTE:

104251550(NDUFV3)

CBOY:

140644367(NDUFV3)

MAME:

142417975(NDUFV3)

CLV:	102084770(NDUFV3)

CNIC:

135985094(NDUFV3)

MUI:	104535327(NDUFV3)

PGUU:

104463087(NDUFV3)

PLET:

104616883(NDUFV3)

EHS:	104512884(NDUFV3)

CMAC:

104479728(NDUFV3)

CUCA:

104059275(NDUFV3)

TEO:	104370557(NDUFV3)

BREG:

104631219(NDUFV3)

OHA:	104327743(NDUFV3)

ACAR:

104521002(NDUFV3)

RTD:	128905904(NDUFV3)

CRID:

134520058(NDUFV3)

LMIC:

141749368(NDUFV3)

AAM:	106483635(NDUFV3)

AROW:

112968430(NDUFV3)

NPD:	112944675(NDUFV3)

TGT:	104579775(NDUFV3)

DNE:	112981971(NDUFV3)

SCAM:

104147111(NDUFV3)

ASN:	102383825(NDUFV3)

AMJ:	102563803(NDUFV3)

CPOO:

109305856(NDUFV3)

GGN:	109302315(NDUFV3)

PSS:	102455697(NDUFV3)

CIZ:	142013803(NDUFV3)

CMY:	102943792(NDUFV3)

CCAY:

125643303(NDUFV3)

LKP:	140917201(NDUFV3)

NDS:	141997207(NDUFV3)

DCC:	119850856(NDUFV3)

TST:	117867991(NDUFV3)

CABI:

116831619(NDUFV3)

MRV:	120396011(NDUFV3)

ACS:	100556574(ndufv3)

ASAO:

132771812(NDUFV3)

PVT:	110074076(NDUFV3)

SUND:

121925813(NDUFV3)

PBI:	103067100(NDUFV3)

PMUR:

107296829(NDUFV3)

CTIG:

120319691(NDUFV3)

TSR:	106546955(NDUFV3)

PGUT:

117669457(NDUFV3)

PCAE:

139316653(NDUFV3)

VKO:	123029145(NDUFV3)

PMUA:

114596119(NDUFV3)

PRAF:

128413055(NDUFV3)

ZVI:	118085474(NDUFV3)

HCG:	128349709(NDUFV3)

GJA:	107109222(NDUFV3)

STOW:

125430643(NDUFV3)

EMC:	129325714(NDUFV3)

XLA:	108707775 108709309

XTR:	100497622(ndufv3)

RTEM:

120921672(NDUFV3)

BBUF:

120994286(NDUFV3)

BGAR:

122930731(NDUFV3)

MUO:	115470536(NDUFV3)

DRE:	100537318(ndufv3)

SRX:	107713724 107748893

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122332268(ndufv3)

OMC:	131546613(ndufv3)

PPRM:

120487270(ndufv3)

RKG:	130075962(ndufv3)

MAMB:

125269613(ndufv3)

CERY:

137036349(ndufv3)

MASI:

127447829

TROS:

130549502(ndufv3)

TDW:	130427993(ndufv3)

MANU:

129452050(ndufv3)

PDAB:

135782608(ndufv3)

IPU:

108266682

PHYP:

113526217(ndufv3)

SMEO:

124383346(ndufv3)

AMEX:

103043544(ndufv3)

EEE:	113590626(ndufv3)

TRU:	101073876(ndufv3)

TFS:	130531313(ndufv3)

TNG:	GSTEN00007119G001

LCO:	104934951(ndufv3)

NCC:	104962086(ndufv3)

CGOB:

115026688(ndufv3)

ELY:	117251256(ndufv3)

EFO:	125900076(ndufv3)

PLEP:

121949061(ndufv3)

SLUC:

116043205(ndufv3)

PFLV:

114564138(ndufv3)

GAT:	120834206(ndufv3)

PPUG:

119229253(ndufv3)

CANA:

137782513

MSAM:

119903499(ndufv3)

CUD:	121506599(ndufv3)

ALAT:

119025453(ndufv3)

MZE:	101475636(ndufv3) 143412308

ONL:	100697907(ndufv3)

OAU:	116312836(ndufv3)

OLA:	110014890(ndufv3)

OML:	112155172(ndufv3)

XMA:	111609223(ndufv3)

XCO:	114147806(ndufv3)

XHE:	116722768(ndufv3)

PRET:

103482419(ndufv3)

PFOR:

103154091(ndufv3)

PLAI:

106934879(ndufv3)

PMEI:

106904183(ndufv3)

GAF:	122839907(ndufv3)

PPRL:

129353168

CVG:	107100087(ndufv3)

CTUL:

119789316(ndufv3)

GMU:	124870962(ndufv3)

NFU:

107389546

KMR:	108238775(ndufv3)

ALIM:

106521800(ndufv3)

CSEM:

103391488(ndufv3)

POV:	109637384(ndufv3)

SSEN:

122765624(ndufv3)

HHIP:

117754512(ndufv3)

HSP:	118119693(ndufv3)

PPLT:

128456190(ndufv3)

LCF:

108897135

SDU:	111228105(ndufv3)

SLAL:

111663449(ndufv3)

XGL:	120802021(ndufv3)

HCQ:	109519262(ndufv3)

BPEC:

110159959(ndufv3)

MALB:

109963761(ndufv3)

BSPL:

114847066(ndufv3)

SSCO:

133993414(ndufv3)

SASA:

106581904(NDUV3) 106586849(ndufv3)

STRU:

115161359(ndufv3)

OTW:	112225276 112243114

OMY:	110501411 110520626

ONE:

115113565

OKI:	109870967(ndufv3) 109871275

OKE:	118366699 118386081

OMM:	135518925 135547266

OCLA:

139380494 139405513

SALP:

111959600 112068347(ndufv3)

SNH:	120058573(ndufv3)

SFON:

129820855

ELS:	105018793(ndufv3)

SFM:	108926921(ndufv3)

PKI:	111834060(ndufv3)

LOC:	102692364(ndufv3)

PSPA:

121327888(ndufv3)

PSEX:

120523083(ndufv3)

LCM:	102366986(NDUFV3)

SPU:

AFIL:

PFLL:

AEC:

PBAR:

VEM:

PGC:

CSOL:

API:

DNX:

AGS:

RMD:

GOE:

PCAN:

BARL:

HCRA:

CVN:

OED:

MYI:

AIRR:

DPOL:

SMM:	Smp_027360