KEGG   ORTHOLOGY: K04341
Entry
K04341                      KO                                     
Symbol
E2.4.2.27
Name
dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase [EC:2.4.2.27]
Pathway
map00521  Streptomycin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R04222  dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    K04341  E2.4.2.27; dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.27  dTDP-dihydrostreptose---streptidine-6-phosphate dihydrostreptosyltransferase
     K04341  E2.4.2.27; dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase
Other DBs
GO: 0047282
Genes
ACEL: acsn021_17350
SGR: SGR_5936(strH)
SGU: SGLAU_01145(strH)
SSUB: CP968_05845
LinkDB

KEGG   ENZYME: 2.4.2.27
Entry
EC 2.4.2.27                 Enzyme                                 
Name
dTDP-dihydrostreptose---streptidine-6-phosphate dihydrostreptosyltransferase;
thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase
Reaction(IUBMB)
dTDP-L-dihydrostreptose + streptidine 6-phosphate = dTDP + O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate [RN:R04222]
Reaction(KEGG)
R04222
Substrate
dTDP-L-dihydrostreptose [CPD:C03442];
streptidine 6-phosphate [CPD:C01121]
Product
dTDP [CPD:C00363];
O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate [CPD:C04767]
History
EC 2.4.2.27 created 1982
Pathway
ec00521  Streptomycin biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K04341  dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase
Genes
ACEL: acsn021_17350
SGR: SGR_5936(strH)
SGU: SGLAU_01145(strH)
SSUB: CP968_05845
Reference
1  [PMID:6768553]
  Authors
Kniep B, Grisebach H.
  Title
Biosynthesis of streptomycin. Purification and properties of a dTDP-L-dihydrostreptose: streptidine-6-phosphate dihydrostreptosyltransferase from Streptomyces griseus.
  Journal
Eur J Biochem 105:139-44 (1980)
DOI:10.1111/j.1432-1033.1980.tb04483.x
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.27
IUBMB Enzyme Nomenclature: 2.4.2.27
ExPASy - ENZYME nomenclature database: 2.4.2.27
BRENDA, the Enzyme Database: 2.4.2.27
CAS: 73699-20-4
LinkDB

KEGG   REACTION: R04222
Entry
R04222                      Reaction                               
Name
dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase
Definition
dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate
Equation
C03442 + C01121 <=> C00363 + C04767
Reaction class
RC00005  C00363_C03442
RC00049  C01121_C04767
Enzyme
2.4.2.27
Pathway
rn00521  Streptomycin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.27
     R04222  dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate
Orthology
K04341  dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase [EC:2.4.2.27]
Other DBs
RHEA: 24395
LinkDB

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