ORTHOLOGY: K04344 Help
Entry
Symbol
CACNA1A, CAV2.1
Name
voltage-dependent calcium channel P/Q type alpha-1A
Pathway
map04723 Retrograde endocannabinoid signaling
map05207 Chemical carcinogenesis - receptor activation
Disease
H00063 Spinocerebellar ataxia (SCA)
H00606 Early infantile epileptic encephalopathy
H01808 Hemiconvulsion-hemiplegia-epilepsy syndrome
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04020 Calcium signaling pathway
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04727 GABAergic synapse
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04725 Cholinergic synapse
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04728 Dopaminergic synapse
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04726 Serotonergic synapse
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04730 Long-term depression
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04723 Retrograde endocannabinoid signaling
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
04721 Synaptic vesicle cycle
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09157 Sensory system
04742 Taste transduction
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09165 Substance dependence
05032 Morphine addiction
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
05033 Nicotine addiction
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
Ion channels [BR:ko04040 ]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
K04344 CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
BRITE hierarchy
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Genes
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Taxonomy UniProt
Reference
Authors
Rose SJ, Kriener LH, Heinzer AK, Fan X, Raike RS, van den Maagdenberg AM, Hess EJ
Title
The first knockin mouse model of episodic ataxia type 2.
Journal
Sequence
Reference
Authors
Hans M, Urrutia A, Deal C, Brust PF, Stauderman K, Ellis SB, Harpold MM, Johnson EC, Williams ME
Title
Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.
Journal
LinkDB
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