Entry Symbol ROCK1
Name Rho-associated protein kinase 1 [EC:
2.7.11.39 ]
Pathway map04270 Vascular smooth muscle contraction
map04670 Leukocyte transendothelial migration
map04810 Regulation of actin cytoskeleton
map05130 Pathogenic Escherichia coli infection
map05163 Human cytomegalovirus infection
Brite KEGG Orthology (KO) [BR:ko00001 ]ko01000 ]ko01001 ]ko03036 ] BRITE hierarchy Genes » show all Taxonomy UniProt Reference Authors Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggio M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G, Brancaccio M
Title Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis.
Journal Reference Authors Ishizaki T, Maekawa M, Fujisawa K, Okawa K, Iwamatsu A, Fujita A, Watanabe N, Saito Y, Kakizuka A, Morii N, Narumiya S
Title The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.
Journal Sequence Reference Authors Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K.
Title Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop.
Journal Reference Authors Winter CG, Wang B, Ballew A, Royou A, Karess R, Axelrod JD, Luo L.
Title Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.
Journal Sequence LinkDB All DBs
