KEGG ORTHOLOGY: K04578

ORTHOLOGY: K04578

Entry

K04578                      KO

Symbol

CRHR1

Name

corticotropin releasing hormone receptor 1

Pathway

map04024

cAMP signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04730

Long-term depression

map04934

Cushing syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04578  CRHR1; corticotropin releasing hormone receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04578  CRHR1; corticotropin releasing hormone receptor 1
   04081 Hormone signaling
    K04578  CRHR1; corticotropin releasing hormone receptor 1
09150 Organismal Systems
  09156 Nervous system
   04730 Long-term depression
    K04578  CRHR1; corticotropin releasing hormone receptor 1
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04578  CRHR1; corticotropin releasing hormone receptor 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04578  CRHR1; corticotropin releasing hormone receptor 1
G protein-coupled receptors [BR:ko04030]
Secretin receptor family
  Hypothalamic hormone
   Corticotropin-releasing hormone (CRH)
    K04578  CRHR1; corticotropin releasing hormone receptor 1

Other DBs

GO:

0015056

TC:	9.A.14.4.3

Genes

HSA:	1394(CRHR1)

PTR:	107966392(CRHR1)

PPS:	100986244(CRHR1)

GGO:	101136616(CRHR1)

PON:	100432200(CRHR1)

PPYG:

129017906(CRHR1)

NLE:	100602096(CRHR1)

HMH:	116475000(CRHR1)

SSYN:

129470177(CRHR1)

MCC:	574095(CRHR1)

MCF:	102124531(CRHR1)

MTHB:

126938927

MNI:	105468357(CRHR1)

CSAB:

103243260(CRHR1)

CATY:

105585760(CRHR1)

PANU:

101003248(CRHR1)

TGE:	112609410(CRHR1)

MLEU:

105555142(CRHR1)

RRO:	104682394(CRHR1)

RBB:	108529368(CRHR1)

TFN:	117087370(CRHR1)

PTEH:

111529275(CRHR1)

CANG:

105520287(CRHR1)

CJC:	100405475(CRHR1) 103793141

SBQ:	101028684(CRHR1)

CIMI:

108318307(CRHR1)

ANAN:

105711245(CRHR1)

CSYR:

103253630

MMUR:

105863672(CRHR1)

LCAT:

123620564(CRHR1)

PCOQ:

105819072(CRHR1)

OGA:	100952699(CRHR1)

MMU:	12921(Crhr1)

MCAL:

110304426(Crhr1)

MPAH:

110331134(Crhr1)

RNO:	58959(Crhr1)

MCOC:

116078094(Crhr1)

ANU:	117709928(Crhr1)

ASYL:

127693610(Crhr1)

MUN:	110545638(Crhr1)

CGE:

100769844

MAUA:

101829697(Crhr1)

PROB:

127217656(Crhr1)

PLEU:

114702275(Crhr1)

PMAV:

102909636(Crhr1)

MORG:

121436283(Crhr1)

MFOT:

126487546

AAMP:

119812485(Crhr1)

CNL:	130876994(Crhr1)

NGI:	103724769(Crhr1)

HGL:	101721828(Crhr1)

CPOC:

100729987(Crhr1)

CCAN:

109684802

DORD:

105998522(Crhr1)

DSP:	122103305(Crhr1)

DMER:

138830413(Crhr1)

PLOP:

125366289(Crhr1)

NCAR:

124980578

MMMA:

107160520(Crhr1)

ITI:	101961253(Crhr1)

OCU:	100302436(CRHR1)

OPI:	101519963(CRHR1)

OCZ:	121162262(CRHR1)

TUP:	102478239(CRHR1)

GVR:	103601001 103601002

CFA:	610380(CRHR1)

CLUD:

112652949(CRHR1)

VVP:

112920686

VLG:	121472725(CRHR1)

NPO:	129493694(CRHR1)

AML:	100475512(CRHR1)

UMR:

103665890

UAR:	123802993(CRHR1)

ELK:

111158111

LLV:

125087989

MPUF:

101681992

MNP:	132004276(CRHR1)

MLK:	131816382(CRHR1)

NVS:

122907570

ORO:	101373186(CRHR1)

EJU:

114196741

ZCA:

113908194

MLX:

118027169

NSU:	110570357(CRHR1)

LWW:

102750183

FCA:	101089308(CRHR1)

PYU:	121020148(CRHR1)

PBG:	122485732(CRHR1)

PVIV:

125151549(CRHR1)

LRUF:

124512837

LGF:	123603883(CRHR1)

AJU:

106988835

PTG:	102962839(CRHR1)

PPAD:

109259750(CRHR1)

PUC:

125927349

PLEZ:

122206998(CRHR1)

HHV:	120244274(CRHR1)

BTA:	281716(CRHR1)

BOM:	102272695(CRHR1)

BIU:	109573320(CRHR1)

BBUB:

102414459(CRHR1)

BBIS:

104983012(CRHR1)

CHX:	102191647(CRHR1)

OAS:	443025(CRHR1)

BTAX:

128065457(CRHR1)

CSUM:

138082705(CRHR1)

ODA:	120866984(CRHR1)

CCAD:

122440095(CRHR1)

MREE:

136149264(CRHR1)

OVR:	110129538(CRHR1)

MBEZ:

129544520(CRHR1)

SSC:	397426(CRHR1)

CFR:	102507830(CRHR1)

CBAI:

105071482(CRHR1)

CDK:	105090500(CRHR1)

VPC:	102527109(CRHR1)

BACU:

103013802(CRHR1)

BMUS:

118887167(CRHR1)

LVE:

103090142

OOR:	101278576(CRHR1)

LALB:

132510825(CRHR1)

DDP:	132414898(CRHR1)

DLE:	111182580(CRHR1)

PCAD:

102995828(CRHR1)

PSIU:

116746306(CRHR1)

PPHC:

136138568(CRHR1)

NASI:

112410282(CRHR1)

ECB:	100065598(CRHR1)

EPZ:	103552912(CRHR1)

EAI:	106836493(CRHR1)

MYB:	102259439(CRHR1)

MYD:	102756414(CRHR1)

MMYO:

118671808(CRHR1)

MLF:	102426185(CRHR1)

MDT:	132218537(CRHR1)

MYUM:

138993640(CRHR1)

PKL:	118726654(CRHR1)

EFUS:

103293166(CRHR1)

MNA:	107530260(CRHR1)

DRO:	112316287(CRHR1)

SHON:

119003697(CRHR1)

AJM:	119062712(CRHR1)

PDIC:

114503302(CRHR1)

PHAS:

123817566(CRHR1)

MMF:	118634053(CRHR1)

PPAM:

129071522(CRHR1)

HAI:	109380260(CRHR1)

RFQ:	117013784(CRHR1)

PALE:

102878226(CRHR1)

PGIG:

120589266(CRHR1)

PVP:

105303517

RAY:	107508175(CRHR1)

MJV:	108403491(CRHR1)

TOD:	119231974(CRHR1)

SARA:

101537586(CRHR1)

SFUM:

130035871(CRHR1)

SETR:

126018034(CRHR1)

LAV:	100659551(CRHR1)

TMU:

101340626

ETF:	101648674(CRHR1)

DNM:

101418035

MDO:	100024819(CRHR1)

GAS:	123246189(CRHR1)

SHR:	100919690(CRHR1)

AFZ:

127560381

PCW:	110215928(CRHR1)

TVP:

118846982

PBRV:

138152761(CRHR1)

MLAO:

141513998(CRHR1)

OAA:

100083324

TACU:

119934972(CRHR1)

GGA:	374218(CRHR1)

PCOC:

116233825

MGP:

100540152

CJO:	107325280(CRHR1)

TPAI:

128088733(CRHR1)

LMUT:

125684656(CRHR1)

NMEL:

110388633(CRHR1)

APLA:

101803845

AACU:

137844568(CRHR1)

ACYG:

106045998(CRHR1)

CATA:

118258894(CRHR1)

AFUL:

116498513(CRHR1)

TGU:

100223670

LSR:	110476969(CRHR1)

SCAN:

103821679

PMOA:

120498402

OTC:	121333017(CRHR1)

PRUF:

121350507(CRHR1)

ATRC:

139601626(CRHR1)

GFR:	102044709(CRHR1)

FAB:	101806078(CRHR1)

OMA:	130264095(CRHR1)

PHI:	102099242(CRHR1)

PMAJ:

107215316

CCAE:

111939929(CRHR1)

CCW:

104698492

CBRC:

103616997

ACOE:

138099340

ETL:	114066938(CRHR1)

ZAB:

102064549

ZLE:	135458496(CRHR1)

ACHL:

103808047

SVG:	106858243(CRHR1)

MMEA:

130583466(CRHR1)

HRT:	120763869(CRHR1)

SATI:

136372351

CFAI:

136301893(CRHR1)

CCIC:

134053145(CRHR1)

FPG:	101910362(CRHR1)

FCH:

102049124

CCRI:

104167815

NNT:	104408321(CRHR1)

SHAB:

115617940(CRHR1)

ACUN:

113489259(CRHR1)

SURA:

141953313(CRHR1)

TALA:

104363087(CRHR1)

ACHC:

115345152(CRHR1)

HALD:

104320084

HLE:	104827971(CRHR1)

AGEN:

126038367

HHAR:

128140799

BBUT:

142035057(CRHR1)

GCL:

LDI:

MNB:

DPUB:

PPUS:

135191759(CRHR1)

AVIT:

104271740

BRHI:

104488910

EGZ:	104134576(CRHR1)

NNI:	104012264(CRHR1)

PCRI:

104037081

PCAO:

104045396(CRHR1)

PADL:

103926077(CRHR1)

AFOR:

103906056(CRHR1)

FGA:	104079143(CRHR1)

CBOR:

142092120(CRHR1)

GSTE:

104264195(CRHR1)

CBOY:

140662427(CRHR1)

MAME:

142419693(CRHR1)

CLV:

102089639

CNIC:

135998066(CRHR1)

MUI:

104543512

PGUU:

104471269(CRHR1)

PLET:

104623091

EHS:

104512215

CMAC:

104486504

CUCA:

104054394(CRHR1)

TEO:	104382683(CRHR1)

BREG:

104636334

GAME:

129195477(CRHR1)

OHA:

104338678

ACAR:

104526974(CRHR1)

CPEA:

104390235(CRHR1)

CVF:	104285398(CRHR1)

RTD:	128919411(CRHR1)

CRID:

134524515(CRHR1)

LMIC:

141732813(CRHR1)

NARQ:

141474713(CRHR1)

AAM:

106497452

AROW:

112962772(CRHR1)

NPD:	112960291(CRHR1)

TGT:

104568392

DNE:	112982770(CRHR1)

SCAM:

104144764(CRHR1)

ASN:	102383267(CRHR1)

AMJ:	102563512(CRHR1)

CPOO:

109318976

GGN:

109302081

PSS:	102445239(CRHR1)

CIZ:

CMY:

CCAY:

LKP:

NDS:	141978551(CRHR1)

DCC:

119849173

CPIC:

101954064

TST:	117869294(CRHR1)

CABI:

116839504(CRHR1)

MRV:

120385088

ACS:	100554822(crhr1)

ASAO:

132778228(CRHR1)

PVT:

110074907

SUND:

121935789(CRHR1)

PBI:	103053136(CRHR1)

PMUR:

107303101

CTIG:

120316066

TSR:	106551069(CRHR1)

PGUT:

117664611(CRHR1)

APRI:

131198562(CRHR1)

PTEX:

NSS:

VKO:

PMUA:

PRAF:

128400103(CRHR1)

ZVI:	118094684(CRHR1)

HCG:	128330034(CRHR1)

STOW:

125445128(CRHR1)

EMC:	129339099(CRHR1)

XLA:	108700863(crhr1.2.L) 373580(crhr1.2.S)

XTR:	100498637(crhr1.2)

NPR:	108802546(CRHR1)

RTEM:

120918292(CRHR1)

ACAT:

141114129(CRHR1)

PADS:

140333129(CRHR1)

BBUF:

121005655

BGAR:

122942056

DTC:	141096022(CRHR1)

PWL:

138299622

MUO:	115481735 115481905

GSH:

117347478

DRE:	567940(crhr1)

SRX:	107740665 107754311

SANH:

107662410 107694956

SGH:	107582913 107585084

CCAR:

109082215 109101841

CAUA:

113046788 113048113

CGIB:

127946907 127952688

PTET:

122334174(crhr1)

LROH:

127159097(crhr1)

GRF:	141315537(crhr1)

OMC:	131536437(crhr1)

PPRM:

120489747(crhr1)

RKG:

130070322

MAMB:

125272492(crhr1)

CIDE:

127509594

CERY:

137010721(crhr1)

MASI:

127450521 127451584

TROS:

130561342(crhr1)

TDW:	130426419(crhr1)

MANU:

129436378(crhr1)

PDAB:

135733922(crhr1)

IPU:	108261365(crhr1) 108273210

IFU:	128601414(crhr1) 128604647

PHYP:

113528562 113533697

SMEO:

124384293 124397173(crhr1)

TFD:	113638007(crhr1) 113652087

TVC:	132846419 132861067(crhr1)

CGAR:

128520366 128544960(crhr1)

NGRA:

132868754(crhr1) 132885865

TRN:	134310082 134335846(crhr1)

AMEX:

103028117(crhr1) 103036295

CMAO:

118821233(crhr1) 118822395

EEE:	113583367 113590078

CHAR:

105890724(crhr1) 105901292

SPIL:

134075819(crhr1) 134077158

ASAD:

121704974 121705034(crhr1)

TRU:

101068283

TFS:

130524985

TNG:	GSTEN00022293G001

LCO:	104935921 104938139

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117246796 117267801(crhr1)

EFO:	125879217(crhr1) 125880668

PLEP:

121958681

SLUC:

116035212(crhr1) 116061376

ECRA:

117937013 117941303

PFLV:

114548037(crhr1) 114568981

GAT:	120819552(crhr1)

PPUG:

119213038

AFB:	129091320 129098197(crhr1)

CLUM:

117748723(crhr1)

PSWI:

130203758

CANA:

137789797

CVE:	137884034(crhr1) 137891944

MSAM:

119896097(crhr1) 119916292

SCHU:

122867879 122869202(crhr1)

EARM:

139300578(crhr1) 139302948

CUD:	121528747 121529141(crhr1)

SPUL:

138593317 138604145(crhr1)

LMIX:

132954295(crhr1) 132955156

HTC:	141784774 141809026(crhr1)

ALAT:

119010188 119014761(crhr1)

ASTR:

137588763 137610291

PKLU:

139216428(crhr1) 139219613

MZE:	101467831 101481663

ONL:	100696279 100703872

OAU:	116319399(crhr1) 116321249

OLA:

101166997

OML:	112154261(crhr1)

CSAI:

133419341(crhr1)

XMA:	102221570 102235780

XCO:	114152235 114160419

XHE:	116727308 116735999

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122821832(crhr1) 122822861

PPRL:

129368025 129373706(crhr1)

CVG:	107089307 107093968

CTUL:

119775988 119781697(crhr1)

GMU:	124862392 124863919 124874700

NFU:	107387289 107395845

KMR:	108228704 108228790(crhr1)

ALIM:

106521999(crhr1) 106528103 106528106

NWH:	119421282(crhr1) 119423850

AOCE:

111568171(crhr1) 111584347

EJA:	138204646 138207715(crhr1)

BFRE:

138624354 138631371(crhr1)

MCEP:

124998300(crhr1) 125023015

CSEM:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:	108873237(crhr1) 108892057

SDU:	111220049 111239794

SLAL:

111657522 111664297

XGL:	120786345(crhr1) 120794740

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110154202(crhr1) 110170190

ENY:	140365437 140369100

MALB:

109962773 109972661

BSPL:

114845891 114860354(crhr1)

SJO:	128379402(crhr1) 128380924

SSCO:

133999376(crhr1) 134003320

TTY:

137171792

GMH:	115531262(crhr1)

SASA:

106600876 106607456

STRU:

115170939 115196407

OTW:	112225893 112258497(crhr1)

OMY:	100136220(crhr1) 110486134

OGO:	124000145(crhr1) 124016118

ONE:	115104025 115110128

OKI:	109892213 109897260

OKE:	118365165 118384390(crhr1)

OMM:	135553939 135555846

OCLA:

139422143 139423892

SALP:

111979890 111981982

SNH:	120033943 120043971

SFON:

129822630 129832870

CCLU:

121551688 121569718

ELS:	105023366(crhr1)

OEP:	134031629 134034073(crhr1)

SFM:	108924751 108941795

PKI:	111856013 111856802

AANG:

118216809(crhr1) 118218028

AROT:

135242967 135247848

CCOG:

133114482(crhr1)

LOC:

102695551

PSPA:

121301780(crhr1)

ARUT:

117433310 117970161

PSEX:

120517679(crhr1)

LCM:	102359764(CRHR2)

CMK:

103187736

CPUN:

140465922

SPU:	105440442 577102

LPIC:

129274097 129275066

LVG:	121425880 121426452 121426819

ARUN:

117300004

AAMU:

139948997

AFIL:

140135437 140149891 140150862 140156307

PFLL:

139114704

DME:	Dmel_CG12370(Dh44-R2) Dmel_CG8422(Dh44-R1)

DER:	6546587 6549335

DSE:	6608855 6609139

DSI:	Dsimw501_GD10893(Dsim_GD10893) Dsimw501_GD11050(Dsim_GD11050)

DYA:	Dyak_GE12470 Dyak_GE13585

DAN:	6495367 6496342

DSR:	110180007 110189202

DPO:	4803884 4805464

DPE:	6590223 6600803

DMN:	108158227 108159235 117185733

DWI:	6640040 6646168

DGR:	6559460 6559739

DMO:	Dmoj_GI19749 Dmoj_GI20281

DAZ:	108615758 108617592

DNV:	108654863 108655198

DHE:	111593191 111600681

DVI:	6624799(Dh44-R1) 6635945(Dh44-R2)

CCAT:

101449447 101459903

BOD:	106621407 106625976

BDR:	105229170 105230520

RZE:	108365247 108368682

AOQ:	129244077 129244164

ALUD:

128866252 128866861

TDA:	119674619 119678702 119681442

MDE:

101891158

SCAC:

106088923

LCQ:	111679333 111684850

LSQ:	119606065 119615699

CVJ:	135961454(Dh44-R1) 135961844(Dh44-R2)

GFS:	119636236 119642198

ECOE:

129950326 129952620

CLON:

129610601 129613286

HIS:	119646766 119661367

AGA:	1276156 1276158

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ADAR:

ACOS:

AAG:	5567138 5570395

AALB:

109409995 109419645 109420199

ASUA:

134208787 134208790

CQU:	CpipJ_CPIJ008821 CpipJ_CPIJ008822

CPII:

120422320 120422324

CBRI:

134828399

CNS:	116345773 116345912

BCOO:

119079432 119079434

LLL:	129794108 129794294

PPAP:

AME:

ACER:

ALAB:

ADR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108726725(Dh44-R1)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139102273(Dh44-r1)

TLN:	139819270(Dh44-r1)

TAME:

143901730(Dh44-r1)

HST:

DQU:

CFO:

FEX:

PMEC:

138931992(Dh44-r1)

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141531790(Dh44-r1)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124217496(Dh44-R1)

NFB:

NLO:

NVG:

AROA:

TCA:	659812(GLEAN_12799) 664316

TMOL:

DPA:

ESIM:

EFOR:

RFG:

AGRG:

CSET:

HAXR:

AGB:

LDC:	111501993 111503323 111511253

DVV:	114331654 114332568

APLN:

108734192

PPYR:

116168431 116169184 116181853

OTU:	111415572 111422149

BMOR:

101743146

BMAN:

114241902

MSEX:

115452421

DPL:	KGM_214005A KGM_214005B

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

CSTB:

CFUM:

CFEL:

CCRN:

API:	100166470 100572659

DNX:	107166904 107166907

AGS:	114120463 114120466

RMD:	113548872 113555054

ACOO:

126842581 126847436

DVT:	126895444 126895446

BTAB:

109030914

DCI:

103511184

CLEC:

106666441 106668989

HHAL:

106680473 106682506 106684546(Dh44-R2)

NLU:	111050624 111052558

LDA:

142333875

HVI:	124365959 124366199 124366279 124366476

MQU:	128995680 129002482 129002817 129003775 129004120

PHU:	Phum_PHUM132710

FOC:	113208944 113211574

TPAL:

117646203 117646269

ZNE:

110832851

CSEC:

111864021

PAME:

138712610(Dh44-R1)

SGRE:

126354276 126354714 126356006

BROR:

134540906

IEL:	124158978 124158979

HAMR:

139692101 139692103

FCD:	110854108 110854109

DPX:	DAPPUDRAFT_290680 DAPPUDRAFT_62157

DMK:	116918228 116918279 123470536

DPZ:	124344592 124344598

AFRA:

136039273

PJA:	122253941 122262900

PCHN:

125040370 125041929 125044905

PMOO:

119582196 119583042

HAME:

121854858 121855626 121879999

PTRU:

123508527 123513930 123514363 123518739 123519985 123519993

ESN:	126981054 126983115 126984010 126987712 126992126

MNZ:	135217334 135217565 135217715 135219286

MRJ:	136835405 136835943 136849257 136855681

PORN:

139755493 139764019 139764652

HAZT:

108679284

EAF:	111696747 111698469 111701867

LSM:	121126785(Dh44-R2) 121129724

TCF:	131881979 131882694 131887768

PPOI:

119097217 119110575

DSV:	119434486 119434568 119441003 119441568 119441573

DALB:

135911069 135911076 135916608 135919429 139054374

RSAN:

119385618 119386231 119386797 119386800

RMP:	119177849 119177851 119178395

VDE:	111242811 111247711 111252529

VJA:	111263185 111264625 111265701 111267806

GOE:

100902518

TUT:	107360191 107366359

DPTE:

113789684 113796876

DFR:	124491759 124500094

CSCU:

111619768 111626245

CVS:	136977560 136985954

PTEP:

107438883 107442483 107452238 107454414 107454507 107454966

ABRU:

129965694 129966168 129968211 129968618 129968964 129969582 129980643 129987622

UDV:	129216465 129219845 129220581 129221141 129221384 129223182 129228461 129228551 129228582 129229934 129230724 129234271

SDM:	118181751 118181820 118184571 118192364 118192468 118192849 118194085 118195921 118199505

LPOL:

106457043 106457542 106457543 106458443 106460107 106460299 106464558 106466149 106473027 106474995 106475300 106478462

PMEO:

129594267 129598669 129599838

CEL:	CELE_C18B12.2(seb-3)

CBR:

CBG_07642

CRQ:	GCK72_025596

PCAN:

112563614 112564446 112565107

LSAX:

BARL:

BGT:

GAE:

CRG:	105337403 105348646

DPOL:

OBI:

OSN:

LJP:

LAK:

NVE:	116612680 5500693 5514687

EPA:	110233123 110249072

ADF:	107328346 107333074

PDAM:

113668401 113668403 113674190 113679685 113684118

SPIS:

111319304 111335166 111335333 111336674 111337040 111340424 111345025 111345378 111346143

XEN:	124440317 124440320

HSY:

130621659

» show all

Reference

PMID:7692441

Authors

Chen R, Lewis KA, Perrin MH, Vale WW

Title

Expression cloning of a human corticotropin-releasing-factor receptor.

Journal

Proc Natl Acad Sci U S A 90:8967-71 (1993)
DOI:10.1073/pnas.90.19.8967

Sequence

[hsa:1394]

LinkDB

ORTHOLOGY: K04579

Entry

K04579                      KO

Symbol

CRHR2

Name

corticotropin releasing hormone receptor 2

Pathway

map04024

cAMP signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04934

Cushing syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04579  CRHR2; corticotropin releasing hormone receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04579  CRHR2; corticotropin releasing hormone receptor 2
   04081 Hormone signaling
    K04579  CRHR2; corticotropin releasing hormone receptor 2
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04579  CRHR2; corticotropin releasing hormone receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04579  CRHR2; corticotropin releasing hormone receptor 2
G protein-coupled receptors [BR:ko04030]
Secretin receptor family
  Hypothalamic hormone
   Corticotropin-releasing hormone (CRH)
    K04579  CRHR2; corticotropin releasing hormone receptor 2

Other DBs

GO:

0015056

Genes

HSA:	1395(CRHR2)

PTR:	129135309(CRHR2)

PPS:	100985319(CRHR2)

GGO:	101140511(CRHR2)

PON:	100443520(CRHR2)

PPYG:

129040510(CRHR2)

NLE:	100602303(CRHR2)

HMH:	116812597(CRHR2)

SSYN:

129490075(CRHR2)

MCC:	697404(CRHR2)

MCF:	102139858(CRHR2)

MTHB:

126950088

MNI:	105475813(CRHR2)

CSAB:

103226271

CATY:

105596184(CRHR2)

PANU:

100997773(CRHR2)

TGE:	112620033(CRHR2)

MLEU:

105533693(CRHR2)

RRO:	104668443(CRHR2) 115891994

RBB:	108532984(CRHR2)

TFN:	117072947(CRHR2)

PTEH:

111523626(CRHR2)

CANG:

105520311(CRHR2)

CJC:	100388111(CRHR2)

SBQ:	101034444(CRHR2)

CIMI:

108303316(CRHR2)

ANAN:

105732861(CRHR2)

CSYR:

103270018(CRHR2)

MMUR:

105855107(CRHR2)

LCAT:

123647043(CRHR2)

ERUF:

138377087(CRHR2)

PCOQ:

105807332(CRHR2)

OGA:	100957419(CRHR2)

MMU:	12922(Crhr2)

MCAL:

110296052(Crhr2)

MPAH:

110315967(Crhr2)

RNO:	64680(Crhr2)

MCOC:

116098955(Crhr2)

ANU:	117720568(Crhr2)

ASYL:

127677461(Crhr2)

MUN:	110555128(Crhr2)

CGE:	100774100(Crhr2)

MAUA:

101840384(Crhr2)

PROB:

127235714(Crhr2)

PLEU:

114689707(Crhr2)

PMAV:

102928629(Crhr2)

MORG:

121439571(Crhr2)

MFOT:

126509553

AAMP:

119807669(Crhr2)

CNL:	130888605(Crhr2)

NGI:	103729449(Crhr2)

HGL:	101722722(Crhr2)

CPOC:

100715306(Crhr2)

CCAN:

109681704(Crhr2)

DORD:

105999966(Crhr2)

DSP:	122120870(Crhr2)

DMER:

138821770(Crhr2)

PLOP:

125345758(Crhr2)

NCAR:

124990813

MMMA:

107146147(Crhr2)

ITI:	101963376(Crhr2)

OCU:

100345681

OPI:	101532200(CRHR2)

OCZ:	121145663(CRHR2)

TUP:	102499284(CRHR2)

GVR:	103581201(CRHR2)

CFA:	482384(CRHR2)

CLUD:

112670669(CRHR2)

VVP:	112935401(CRHR2)

VLG:	121474472(CRHR2)

NPO:	129502837(CRHR2)

AML:	100476464(CRHR2)

UMR:	103658941(CRHR2)

UAH:	113266912(CRHR2)

UAR:	123789105(CRHR2)

ELK:

111147340

LLV:

125081165

MPUF:

101683507(CRHR2)

MNP:	132015828(CRHR2)

MLK:	131829576(CRHR2)

NVS:	122904077(CRHR2)

ORO:	101380742(CRHR2)

EJU:	114221230(CRHR2)

ZCA:	113911766(CRHR2)

MLX:	118020932(CRHR2)

NSU:	110580044(CRHR2)

LWW:	102747389(CRHR2)

FCA:	101095242(CRHR2)

PYU:	121028523(CRHR2)

PCOO:

112866375(CRHR2)

PBG:	122488067(CRHR2)

PVIV:

125161280(CRHR2)

LRUF:

124524553

LGF:	123606652(CRHR2)

AJU:

106968685

PTG:	102950703(CRHR2)

PPAD:

109263924(CRHR2)

PUC:

125930029

PLEZ:

122209526(CRHR2)

HHV:	120230283(CRHR2)

BTA:	521831(CRHR2)

BOM:	102270917(CRHR2)

BIU:	109557474(CRHR2)

BBUB:

102396867(CRHR2)

BKE:	129659252(CRHR2)

BBIS:

104980487(CRHR2)

CHX:	102186367(CRHR2)

OAS:	101102228(CRHR2)

BTAX:

128046379(CRHR2)

CSUM:

138079911(CRHR2)

ODA:	120877397(CRHR2)

CCAD:

122438423(CRHR2)

MREE:

136170529(CRHR2)

OVR:	110136671(CRHR2)

MBEZ:

129552484(CRHR2)

SSC:	100240719(CRHR2)

CFR:	102511635(CRHR2)

CBAI:

105081909(CRHR2)

CDK:	105095848(CRHR2)

VPC:	102543610(CRHR2)

BACU:

103019732(CRHR2)

BMUS:

118901157(CRHR2)

LVE:	103085744(CRHR2)

OOR:	101277908(CRHR2)

LALB:

132524658(CRHR2)

GMF:	115853799(CRHR2)

DDP:	132430683(CRHR2)

DLE:	111180010(CRHR2)

PCAD:

102980177(CRHR2)

PSIU:

116759357(CRHR2)

PPHC:

136128601(CRHR2)

NASI:

112406292(CRHR2)

ECB:	100055029(CRHR2)

EPZ:	103541706(CRHR2)

EAI:	106831063(CRHR2)

MYB:	102263180(CRHR2)

MYD:	102770525(CRHR2)

MMYO:

118665683(CRHR2)

MLF:	102435321(CRHR2)

MDT:	132211521(CRHR2)

MYUM:

139016998(CRHR2)

PKL:	118727801(CRHR2)

EFUS:

103291508(CRHR2)

MNA:	107544382(CRHR2)

DRO:	112306974(CRHR2)

SHON:

118983559(CRHR2)

AJM:	119035284(CRHR2)

PDIC:

114507855(CRHR2)

PHAS:

123812057(CRHR2)

MMF:	118619960(CRHR2)

PPAM:

129068890(CRHR2)

HAI:	109381352(CRHR2)

RFQ:	117012053(CRHR2)

PALE:

102888327(CRHR2)

PGIG:

120601955(CRHR2)

PVP:	105308616(CRHR2)

RAY:	107499558(CRHR2)

MJV:	108403654(CRHR2)

TOD:	119244114(CRHR2)

SARA:

101551464(CRHR2)

SFUM:

130027510(CRHR2)

SETR:

126025483(CRHR2)

LAV:	100672505(CRHR2)

TMU:

101354427

ETF:	101651659(CRHR2)

DNM:	101411996(CRHR2)

MDO:	100021369(CRHR2)

GAS:	123230630(CRHR2)

SHR:

100932343

AFZ:

127549631

PCW:	110192979(CRHR2)

TVP:	118831182(CRHR2)

MLAO:

141496677(CRHR2)

OAA:	100093509(CRHR2)

TACU:

119936177(CRHR2)

GGA:	395105(CRHR2)

PCOC:

116238271

MGP:	100540541(CRHR2)

CJO:	107308798(CRHR2)

TPAI:

128085806(CRHR2)

LMUT:

125696264(CRHR2)

NMEL:

110394530(CRHR2)

APLA:

101799096(CRHR2)

AACU:

137852051(CRHR2)

ACYG:

106036863(CRHR2)

CATA:

118251795(CRHR2)

AFUL:

116486894(CRHR2)

TGU:	100219758(CRHR2)

LSR:

110480020

SCAN:

103812695(CRHR2)

PMOA:

120510600(CRHR2)

OTC:	121338177(CRHR2)

PRUF:

121365709(CRHR2)

ATRC:

139590772(CRHR2)

GFR:	102039773(CRHR2)

FAB:	101814931(CRHR2)

OMA:	130250163(CRHR2)

PHI:	102110154(CRHR2)

PMAJ:

107200884(CRHR2)

CCAE:

111925460

CCW:	104686406(CRHR2)

CBRC:

103623934(CRHR2)

ACOE:

138106168(CRHR2)

ETL:

114069474

ZAB:	102070019(CRHR2)

ZLE:	135443543(CRHR2)

SVG:	106851638(CRHR2)

MMEA:

130576316(CRHR2)

HRT:	120751901(CRHR2)

SATI:

136358047(CRHR2)

CFAI:

136299746(CRHR2)

CCIC:

134044304(CRHR2)

FPG:	101920489(CRHR2)

FCH:	102050174(CRHR2)

CCRI:

104162062

NNT:	104408554(CRHR2)

SHAB:

115609973(CRHR2)

ACUN:

113476244(CRHR2)

SURA:

141953788(CRHR2)

TALA:

104358627(CRHR2)

ACHC:

115339791(CRHR2)

HALD:

104321934

HLE:	104827899(CRHR2)

AGEN:

126037846

HHAR:

128150992(CRHR2)

BBUT:

142038717(CRHR2)

GCL:

127013038

CSTI:

104561287

DPUB:

104298974(CRHR2)

PPUS:

135185561(CRHR2)

AVIT:

104279714(CRHR2)

EGZ:	104130958(CRHR2)

NNI:	104021748(CRHR2)

PCRI:

104038893

PCAO:

104052477(CRHR2)

PADL:

103924739(CRHR2)

AFOR:

103896193

FGA:	104073135(CRHR2)

CBOR:

142079669(CRHR2)

GSTE:

104263783(CRHR2)

CBOY:

140647189(CRHR2)

MAME:

142406552(CRHR2)

CLV:

102097303

CNIC:

135985112(CRHR2)

MUI:

104543828

PGUU:

104464410(CRHR2)

CUCA:

104056971(CRHR2)

BREG:

104635151

GAME:

129203357(CRHR2)

OHA:	104326235(CRHR2)

ACAR:

104524294

CPEA:

104388460(CRHR2)

CVF:	104282045(CRHR2)

RTD:	128905729(CRHR2)

CRID:

134511009(CRHR2)

LMIC:

141738581(CRHR2)

NARQ:

141470827(CRHR2)

AAM:	106493060(CRHR2)

AROW:

112969227(CRHR2)

NPD:	112958116(CRHR2)

TGT:

104580008

DNE:	112981597(CRHR2)

SCAM:

104140434(CRHR2)

ASN:	102387930(CRHR2)

AMJ:	102561224(CRHR2)

CPOO:

109306505(CRHR2)

GGN:	109291194(CRHR2)

PSS:	102458117(CRHR2)

CIZ:	142008949(CRHR2)

CMY:	102933353(CRHR2)

CCAY:

125631176(CRHR2)

LKP:	140907847(CRHR2)

NDS:	141983341(CRHR2)

DCC:	119851204(CRHR2)

CPIC:

101939558(CRHR2)

TST:	117871977(CRHR2)

CABI:

116815907(CRHR2)

MRV:	120397920(CRHR2)

ACS:	100563346(crhr2)

ASAO:

132779015(CRHR2)

PVT:	110085840(CRHR2)

SUND:

121933010(CRHR2)

PMUR:

107284360(CRHR2)

CTIG:

120317701(CRHR2)

TSR:	106549549(CRHR2)

PGUT:

117654771(CRHR2)

APRI:

131197826(CRHR2)

PTEX:

113447986

NSS:

113426406

VKO:	123020807(CRHR2)

PMUA:

114607562(CRHR2)

PRAF:

128398444(CRHR2)

ZVI:	118091963(CRHR2)

HCG:	128331506(CRHR2)

GJA:

107114819

STOW:

125441220

EMC:	129337365(CRHR2)

XLA:	108718463(crhr2.L) 378608(crhr2.S)

NPR:	108796655(CRHR2)

RTEM:

120939842(CRHR2)

ACAT:

141144114(CRHR2)

PADS:

140331722(CRHR2)

BBUF:

121000711(CRHR2)

BGAR:

122938241 122938614

DTC:	141095825(CRHR2)

PWL:	138261734(CRHR2)

MUO:	115466529(CRHR2)

GSH:	117354363(CRHR2)

DRE:

100335005

SRX:	107711682 107727503(crhr2)

SANH:

107660401 107671670

SGH:	107567879(crhr2) 107593817

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

ASAD:

TRU:

TFS:

LCO:

NCC:	104942411(crhr2)

TBEN:

117488851

CGOB:

115022986(crhr2)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

CANA:

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:

ALAT:

ASTR:

PKLU:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:	102227710(crhr2)

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

106914247(crhr2)

GAF:

122841306

PPRL:

129361952

CVG:	107081692(crhr2)

CTUL:

GMU:

NFU:

KMR:

ALIM:

106533190(crhr2)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

MALB:

BSPL:

SJO:

SSCO:

TTY:

GMH:

SASA:

STRU:

OTW:	112226780 112260650

OMY:	110508566 110530497

OGO:	124009703 124041733

ONE:	115102941 115114577

OKI:	109871452 109875294

OKE:	118394823 118401948

OMM:	135512305 135558854

OCLA:

139376183 139386900

SALP:

111957248

SNH:	120020067 120055597

SFON:

129813693 129824178

CCLU:

121535367 121581055

ELS:	105019874(crhr2)

OEP:

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:

RTP:	109935666 109937392

CPLA:

122540028 122548922

CPUN:

140476973

HOC:	132815489 132830743

SCAU:

STOZ:

LERI:

HAKA:

PMRN:

116937863 116943861 116949709

LRJ:	133345300 133346182 133355939

BFO:	118423782 118424615 118424967 118424968

BBEL:

109474508 109474516 109477985 109479379 109486539 109486563

CIN:	100179423 104265745

SCLV:

120332473

CLEP:

143451626 143451643 143451676 143451705 143451707 143451741 143451755 143451765 143451773 143451776 143451780 143451800 143451817 143451827 143452068

SPU:	100891952 585532 764176

LPIC:

129274263 129275227

LVG:	121426209 121426537

AJJ:	139958645 139958657 139958733

APLC:

110974889 110976690 110983099

ARUN:

117295035 117299997 117300263

AAMU:

139940905 139948934 139949054

AFIL:

140135938 140151505

SKO:	100313581(Crhr)

PFLL:

SOY:

ACOO:

DVT:

PJA:	122246415 122257006

HAME:

121867048 121877322

PCLA:

123758913 123767200 123768826

CQD:	128689699 138851413

EAF:

111702467

DSV:	119440758 119449469

RSAN:

119382622

RMP:	119162961 119164990

VDE:

111253333

VJA:	111269009 111273135

DFR:

CSCU:

CVS:

ABRU:

LPOL:

106476694 106478583 106478584

NAI:	NECAME_04845

LOA:	LOAG_07719

TSP:

Tsp_01058

LGI:	LOTGIDRAFT_141716

PVUL:

126831667

BARL:

143278154 143293949 143294330

BGT:	106051400 106075219 106075666 106075668

HRF:

124135097

HRJ:	124260619 124281100

HASI:

137255409 137256015

HCRA:

139464345 139464634

CRG:	105320567 105336150

CANU:

128162736 128164052 128178032

CVN:	111111182 111114967

OED:	125665695 125666078

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106870026 106871453 106875237

OSN:	115214785 115215927 115218117

LAK:	106153131 106156885 106165168 106165372 106168451

LLON:

DGT:

HSY:

Reference

PMID:8536644

Authors

Liaw CW, Lovenberg TW, Barry G, Oltersdorf T, Grigoriadis DE, de Souza EB

Title

Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.

Journal

Endocrinology 137:72-7 (1996)
DOI:10.1210/endo.137.1.8536644

Sequence

[hsa:1395]

LinkDB

DBGET integrated database retrieval system