KEGG ORTHOLOGY: K04717

ORTHOLOGY: K04717

Entry

K04717                      KO

Symbol

SGPP2

Name

sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]

Pathway

map00600

Sphingolipid metabolism

map01100

Metabolic pathways

map04071

Sphingolipid signaling pathway

Reaction

R06520

3-sn-phosphatidate phosphohydrolase

R06521

3-sn-phosphatidate phosphohydrolase

R06522

3-sn-phosphatidate phosphohydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K04717  SGPP2; sphingosine-1-phosphate phosphotase 2
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04717  SGPP2; sphingosine-1-phosphate phosphotase 2

Other DBs

GO:

0042392

Genes

HSA:	130367(SGPP2)

PTR:	470726(SGPP2)

PPS:	100976002(SGPP2)

GGO:	101154040(SGPP2)

PON:	100462316(SGPP2)

PPYG:

129031254(SGPP2)

NLE:	100592130(SGPP2)

HMH:	116465318 116810242(SGPP2)

SSYN:

129488496(SGPP2)

MCC:	705674(SGPP2)

MCF:	102135818(SGPP2)

MTHB:

126932847

MNI:	105481305(SGPP2)

CSAB:

103217939(SGPP2)

CATY:

105587000(SGPP2)

PANU:

101016966(SGPP2)

TGE:	112636112(SGPP2)

MLEU:

105550934(SGPP2)

RRO:	104655908(SGPP2)

RBB:	108532648(SGPP2)

TFN:	117094464(SGPP2)

PTEH:

111549088(SGPP2)

CANG:

105518783(SGPP2)

CJC:	100407081(SGPP2)

SBQ:	101051796(SGPP2)

CIMI:

108309126(SGPP2)

ANAN:

105712908(SGPP2)

CSYR:

103260071(SGPP2)

MMUR:

105858642(SGPP2)

LCAT:

123643625(SGPP2)

ERUF:

138382113(SGPP2)

PCOQ:

105808772(SGPP2)

OGA:	100963481(SGPP2)

MMU:	433323(Sgpp2)

MCAL:

110291335(Sgpp2)

MPAH:

110322485(Sgpp2)

RNO:	301543(Sgpp2)

MCOC:

116089242(Sgpp2)

ANU:	117705243(Sgpp2)

ASYL:

127693038(Sgpp2)

MUN:	110549410(Sgpp2)

CGE:	100760822(Sgpp2)

MAUA:

101828898(Sgpp2)

PROB:

127226483(Sgpp2)

PLEU:

114706790(Sgpp2)

PMAV:

102920475(Sgpp2)

MORG:

121447305(Sgpp2)

MFOT:

126512964

AAMP:

119821637(Sgpp2)

CNL:	130870476(Sgpp2)

NGI:	103727771(Sgpp2)

HGL:	101701693(Sgpp2)

CPOC:

100731261(Sgpp2)

CCAN:

109698828(Sgpp2)

DORD:

105987962(Sgpp2)

DSP:	122107414(Sgpp2)

DMER:

138823143(Sgpp2)

PLOP:

125350258(Sgpp2)

NCAR:

124981069

MMMA:

107138739(Sgpp2)

ITI:	101977472(Sgpp2)

OCU:

100357833

OPI:	101529574(SGPP2)

OCZ:	121158163(SGPP2)

TUP:	102497979(SGPP2)

GVR:	103609253(SGPP2)

CFA:	610884(SGPP2)

CLUD:

112656620(SGPP2)

VVP:	112922503(SGPP2)

VLG:	121480542(SGPP2)

NPO:	129522679(SGPP2)

AML:	105234969(SGPP2)

UMR:	103662865(SGPP2)

UAH:	113250408(SGPP2)

UAR:	123778090(SGPP2)

ELK:

111138525

LLV:

125096034

MPUF:

101681375(SGPP2)

MNP:	132013592(SGPP2)

MLK:	131827399(SGPP2)

NVS:	122902353(SGPP2)

ORO:	101365224(SGPP2)

EJU:	114210860(SGPP2)

ZCA:	113920266(SGPP2)

MLX:	118012006(SGPP2)

MANO:

123838306(SGPP2)

NSU:	110592343(SGPP2)

LWW:	102743524(SGPP2)

FCA:	101083024(SGPP2)

PYU:	121014504(SGPP2)

PCOO:

112848540(SGPP2)

PBG:	122481830(SGPP2)

PVIV:

125173363(SGPP2)

LRUF:

124514772

LGF:	123599536(SGPP2)

AJU:

106975905

PTG:	107180011(SGPP2)

PPAD:

109264996(SGPP2)

PUC:

125911741

PLEZ:

122226696(SGPP2)

HHV:	120234842(SGPP2)

CCRU:

144218642(SGPP2)

BTA:	100337041(SGPP2)

BOM:	102286517(SGPP2)

BIU:	109575817(SGPP2)

BJV:	133229673(SGPP2)

BBUB:

102409064(SGPP2)

BKE:	129646814(SGPP2)

BBIS:

104986515(SGPP2)

CHX:	102183470(SGPP2)

OAS:	101116130(SGPP2)

OCAN:

138432924(SGPP2)

BTAX:

128067857(SGPP2)

CSUM:

138076337(SGPP2)

ODA:	120854472(SGPP2)

CCAD:

122426310(SGPP2)

MREE:

136163195(SGPP2)

OVR:	110148653(SGPP2)

MBEZ:

129538508(SGPP2)

SSC:	100524832(SGPP2)

CFR:	102506559(SGPP2)

CBAI:

105064059(SGPP2)

CDK:	105098290(SGPP2)

VPC:	102543563(SGPP2)

BACU:

102998333 102998371(SGPP2)

BMUS:

118897939(SGPP2)

LVE:	103081882(SGPP2)

OOR:	101276880(SGPP2)

LALB:

132522057(SGPP2)

GMF:	115842235(SGPP2)

DDP:	132427981(SGPP2)

DLE:	111171871(SGPP2)

PCAD:

102990066(SGPP2)

PSIU:

116756572(SGPP2)

PPHC:

136125439(SGPP2)

NASI:

112411804(SGPP2)

ECB:	100060934(SGPP2)

EPZ:	103547286(SGPP2)

EAI:	106832476(SGPP2)

MYB:	102259379(SGPP2)

MYD:	102762633(SGPP2)

MMYO:

118661275(SGPP2)

MLF:	102438562(SGPP2)

MDT:	132238284(SGPP2)

MYUM:

139015052(SGPP2)

PKL:	118709056(SGPP2)

EFUS:

103289269(SGPP2)

MNA:	107526694(SGPP2)

DRO:	112307811(SGPP2)

SHON:

118975362(SGPP2)

AJM:	119050966(SGPP2)

PDIC:

114495375(SGPP2)

PHAS:

123828190(SGPP2)

MMF:	118625850(SGPP2)

PPAM:

129080616(SGPP2)

HAI:	109396189(SGPP2)

RFQ:	117025771(SGPP2)

PALE:

102894969(SGPP2)

PGIG:

120587707(SGPP2)

PVP:	105291100(SGPP2)

RAY:	107516746(SGPP2)

MJV:	108398001(SGPP2)

TOD:	119256253(SGPP2)

SARA:

101557193(SGPP2)

SFUM:

130021064(SGPP2)

SETR:

126000985(SGPP2)

LAV:	100669348(SGPP2)

TMU:

101356122

ETF:	101644553(SGPP2)

DNM:	101419582(SGPP2)

MDO:	100022862(SGPP2)

GAS:	123240169(SGPP2)

SHR:	100920724(SGPP2)

AFZ:

127553054

PCW:	110219500(SGPP2)

TVP:	118848235(SGPP2)

PBRV:

138174326(SGPP2)

MLAO:

141490893(SGPP2)

OAA:	100074162(SGPP2)

TACU:

119930608(SGPP2)

GGA:	424813(SGPP2)

PCOC:

116230932(SGPP2)

MGP:	100550401(SGPP2)

CJO:	107318029(SGPP2)

TPAI:

128081814(SGPP2)

LMUT:

125697876(SGPP2)

NMEL:

110397785(SGPP2)

APLA:

101797259(SGPP2)

AACU:

137861094(SGPP2)

OJA:	118171736(SGPP2)

ACYG:

106036188(SGPP2)

CATA:

118247045(SGPP2)

AFUL:

116492578(SGPP2)

TGU:	100226252(SGPP2)

LSR:	110483631(SGPP2)

VMC:	128812432(SGPP2)

VCHA:

128793224(SGPP2)

AIB:	137480082(SGPP2)

SCAN:

103815661(SGPP2)

PMOA:

120508563(SGPP2)

OTC:	121341164(SGPP2)

PRUF:

121357974(SGPP2)

ATRC:

139594876(SGPP2)

MATE:

118690399(SGPP2)

MAEN:

136560646(SGPP2)

GFR:	102043416(SGPP2)

FAB:	101809677(SGPP2)

OMA:	130256980(SGPP2)

PHI:	102101175(SGPP2)

PMAJ:

107209013(SGPP2)

CCAE:

111933562(SGPP2)

CCW:	104693093(SGPP2)

CBRC:

103612041(SGPP2)

ACOE:

138114629(SGPP2)

ETL:	114067632(SGPP2)

ZAB:	102068032(SGPP2)

ZLE:	135451734(SGPP2)

ACHL:

103801979(SGPP2)

SVG:	106855136(SGPP2)

MMEA:

130585399(SGPP2)

HRT:	120757446(SGPP2)

SATI:

136365630(SGPP2)

CFAI:

136294995(SGPP2)

CCIC:

134047888(SGPP2)

FPG:	101914913(SGPP2)

FCH:	102053072(SGPP2)

FRS:	119156598(SGPP2)

NNT:	104402664(SGPP2)

SHAB:

115612053(SGPP2)

ACUN:

113483359(SGPP2)

ANOC:

141963066(SGPP2)

SURA:

141947288(SGPP2)

TALA:

104365207(SGPP2)

ACHC:

115347624(SGPP2)

HALD:

104320842(SGPP2)

HLE:	104832288(SGPP2)

AGEN:

126039893

HHAR:

128149421(SGPP2)

BBUT:

142032787(SGPP2)

GCL:

127020136

CSTI:

104560326(SGPP2)

LDI:	104349562(SGPP2)

MNB:	103769926(SGPP2)

DPUB:

104297650(SGPP2)

PPUS:

135180401(SGPP2)

IIN:	128970871(SGPP2)

AVIT:

104281235(SGPP2)

BRHI:

104489353(SGPP2)

EGZ:	104135441(SGPP2)

NNI:	104012997(SGPP2)

PCRI:

104023768(SGPP2)

PCAO:

104040154(SGPP2)

PARX:

142059923(SGPP2)

PADL:

103917899

AFOR:

103896736(SGPP2)

FGA:	104078608(SGPP2)

CBOR:

142085567(SGPP2)

GSTE:

104259034(SGPP2)

CBOY:

140654830(SGPP2)

MAME:

142412334(SGPP2)

CLV:	102092199(SGPP2)

CNIC:

135991454(SGPP2)

PGUU:

104467372(SGPP2)

PLET:

104613621(SGPP2)

EHS:	104506484(SGPP2)

CUCA:

104058800(SGPP2)

TEO:	104382348(SGPP2)

BREG:

104642251(SGPP2)

GAME:

129210186(SGPP2)

OHA:	104337999(SGPP2)

ACAR:

104522075(SGPP2)

CPEA:

104392269(SGPP2)

CVF:	104291012(SGPP2)

RTD:	128911525(SGPP2)

CRID:

134517472(SGPP2)

LMIC:

141744938(SGPP2)

NARQ:

141468674(SGPP2)

AAM:

106485849

AROW:

112969612(SGPP2)

NPD:	112947966(SGPP2)

TGT:	104569001(SGPP2)

DNE:	112988929(SGPP2)

SCAM:

104144660(SGPP2)

ASN:	102382033(SGPP2)

AMJ:	102557931(SGPP2)

CPOO:

109308643(SGPP2)

GGN:	109288203(SGPP2)

PSS:	102450918(SGPP2)

CIZ:	142018368(SGPP2)

CMY:	102946621(SGPP2)

CCAY:

125642928(SGPP2)

LKP:	140917349(SGPP2)

NDS:	141994007(SGPP2)

DCC:	119861054(SGPP2)

CPIC:

101946541(SGPP2)

TST:	117883321(SGPP2)

CABI:

116838437(SGPP2)

MRV:	120372303(SGPP2)

ACS:	100566481(sgpp2)

ASAO:

132770678(SGPP2)

PVT:	110079978(SGPP2)

SUND:

121925195(SGPP2)

PBI:	103057174(SGPP2)

PMUR:

107289157(SGPP2)

CTIG:

120307590(SGPP2)

TSR:	106540099(SGPP2)

PGUT:

117678383(SGPP2)

PCAE:

139318561(SGPP2)

APRI:

131200652(SGPP2)

PTEX:

113436846(SGPP2)

NSS:	113409868(SGPP2)

VKO:	123024842(SGPP2)

PMUA:

114597792(SGPP2)

PRAF:

128414568(SGPP2)

ZVI:	118093453(SGPP2)

HCG:	128350412(SGPP2)

GJA:	107115866(SGPP2)

STOW:

125438314(SGPP2)

EMC:	129331698(SGPP2)

XLA:	100036888(sgpp2.L) 108717467(sgpp2.S)

XTR:	100489794(sgpp2)

NPR:	108796930(SGPP2)

RTEM:

120936578(SGPP2)

ACAT:

141139634(SGPP2)

PADS:

140328342(SGPP2)

BBUF:

120997730(SGPP2)

BGAR:

122935941(SGPP2)

DTC:	141095238(SGPP2)

PWL:	138265604(SGPP2)

MUO:	115479171(SGPP2)

GSH:	117367018(SGPP2)

DRE:	100330698(sgpp2)

SRX:	107705636 107722257

SANH:

107669878 107670120(sgpp2)

SGH:	107558808 107585790

CCAR:

109104165 109104170

CAUA:

113058699

CGIB:

128029044

PTET:

122358828(sgpp2)

LROH:

127177038(sgpp2)

OMC:	131520364(sgpp2)

PPRM:

120483580(sgpp2)

RKG:	130073152(sgpp2)

MAMB:

125248633(sgpp2)

CIDE:

127495916

CERY:

137004963(sgpp2)

MASI:

127422234 127429900

TROS:

130564850(sgpp2)

TDW:	130428610(sgpp2)

MANU:

129438590(sgpp2)

PDAB:

135771825(sgpp2)

IPU:	108277594 108277997

IFU:	128621488 128621685

PHYP:

113544525

SMEO:

124394586(sgpp2)

TFD:	113637873(sgpp2)

TVC:	132858016(sgpp2)

CGAR:

128533642(sgpp2)

NGRA:

132900952(sgpp2)

TRN:	134334295(sgpp2)

AMEX:

103045304(sgpp2)

CMAO:

118797997(sgpp2)

EEE:	113578720(sgpp2)

CHAR:

105890585(sgpp2)

SPIL:

134099581(sgpp2)

ASAD:

121683881(sgpp2)

TRU:	101075825(sgpp2)

TFS:	130534531(sgpp2)

TNG:	GSTEN00026737G001 GSTEN00026738G001

LCO:	104934363(sgpp2)

NCC:

104948104

TBEN:

117475906(sgpp2)

CGOB:

115017976(sgpp2)

PGEO:

117457701(sgpp2)

GACU:

117540024(sgpp2)

EMAC:

134880807(sgpp2)

ELY:	117259546(sgpp2)

EFO:	125888257(sgpp2)

PLEP:

121943690(sgpp2)

SLUC:

116038901(sgpp2)

ECRA:

117939798(sgpp2)

ESP:	116673003(sgpp2)

PFLV:

114553071(sgpp2)

PPUG:

119214998(sgpp2)

AFB:	129095066(sgpp2)

CLUM:

117741548(sgpp2)

CANA:

137791020(sgpp2)

CVE:	137872050(sgpp2)

MSAM:

119882788(sgpp2)

SCHU:

122878856(sgpp2)

EARM:

139285662(sgpp2)

CUD:	121523985(sgpp2)

SPUL:

138604707(sgpp2)

LMIX:

132979813(sgpp2)

HTC:	141798401(sgpp2)

ALAT:

119008881(sgpp2)

ASTR:

137597019(sgpp2)

PKLU:

139200323(sgpp2)

MZE:	101471415(sgpp2)

ONL:	100698709(sgpp2)

OAU:	116328148(sgpp2)

OLA:	101156907(sgpp2)

OML:	112149309(sgpp2)

CSAI:

133442234(sgpp2)

XMA:	102225026(sgpp2)

XCO:	114161625(sgpp2)

XHE:	116737385(sgpp2)

PRET:

103474930(sgpp2)

PFOR:

103145235(sgpp2)

PLAI:

106953862(sgpp2)

PMEI:

106920630(sgpp2)

GAF:	122832568(sgpp2)

PPRL:

129358693(sgpp2)

CVG:

107081276

CTUL:

119774559(sgpp2)

GMU:	124884485(sgpp2)

NFU:	107380792(sgpp2)

KMR:	108228397(sgpp2)

ALIM:

106523275(sgpp2)

NWH:	119429236 119429238

AOCE:

111577125(sgpp2)

EJA:	138197013(sgpp2)

BFRE:

138616954(sgpp2)

MCEP:

125013098(sgpp2)

CSEM:

103377830(sgpp2)

POV:	109634441(sgpp2)

SSEN:

122773506(sgpp2)

SSOE:

131462574(sgpp2)

HHIP:

117773456(sgpp2)

HSP:	118105667(sgpp2)

PPLT:

128440863(sgpp2)

SMAU:

118298896(sgpp2)

LCF:

108888205

SDU:	111232860(sgpp2)

SLAL:

111671281(sgpp2)

XGL:	120792150(sgpp2)

HCQ:	109510750(sgpp2)

SSCV:

125971774(sgpp2)

SBIA:

133505178(sgpp2)

PEE:	133405510(sgpp2)

PTAO:

133482746(sgpp2)

BPEC:

110154580(sgpp2)

ENY:	140371800(sgpp2)

MALB:

109951303(sgpp2)

BSPL:

114867693(sgpp2)

SJO:	128360661(sgpp2)

SSCO:

133980488(sgpp2)

TTY:	137185709(sgpp2)

GMH:	115560836(sgpp2)

SASA:

106581310(sgpp2) 106613137

STRU:

115206527

OTW:	112267254(sgpp2)

OMY:	110504111(sgpp2)

OGO:	124006527(sgpp2)

ONE:	115141962(sgpp2)

OKI:	109882821(sgpp2)

OKE:

118374414

OMM:	135546602(sgpp2)

OCLA:

139383139

SALP:

111957842(sgpp2)

SNH:	120028482(sgpp2)

SFON:

129831807(sgpp2)

CCLU:

121567705

ELS:	105017512(sgpp2)

OEP:	134028823(sgpp2)

SFM:	108932149(sgpp2)

PKI:	111860299(sgpp2)

AANG:

118208881(sgpp2)

AROT:

135236825(sgpp2)

CCOG:

133108078(sgpp2)

LOC:	102693517(sgpp2)

PSPA:

121323448 121326801(sgpp2)

ARUT:

117416540(sgpp2)

PSEX:

120531011(sgpp2)

LCM:	102359263(SGPP2)

CMK:	103176344(sgpp2)

RTP:	109914278(sgpp2) 109919317

CPLA:

122540352 122555849(sgpp2)

CPUN:

140479017(sgpp2) 140487013

HOC:	132821571(sgpp2) 132833619

SCAU:

119950863 119976444(sgpp2)

LERI:

129703724(sgpp2) 129711581

HAKA:

140718378 140725464(sgpp2)

PMRN:

116946847

LRJ:	133351227(SGPP2)

SPU:

LPIC:

AJJ:

APLC:

ARUN:

117287703 117296106 117299773

AAMU:

139948393 139948400 139948406

CNS:

AGRG:

LDC:

DCI:

HAZT:

DSV:

RSAN:

DFR:

CANU:

CVN:	111111654 111111935

MMER:

RPHI:

DPOL:

MAEA:

HSY:

SRE:	PTSG_03097

DDI:	DDB_G0272260(sppA)

DPP:	DICPUDRAFT_149430

ACAN:

ACA1_369180

BAL:	BACI_c22090

BCR:	BCAH187_A2364

BNC:

BCN_2182

BCF:

bcf_11300

» show all

Reference

PMID:12411432

Authors

Ogawa C, Kihara A, Gokoh M, Igarashi Y

Title

Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2.

Journal

J Biol Chem 278:1268-72 (2003)
DOI:10.1074/jbc.M209514200

Sequence

[hsa:130367]

LinkDB

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