Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04020 Calcium signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04024 cAMP signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04022 cGMP-PKG signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09144 Cellular community - eukaryotes
04530 Tight junction
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04929 GnRH secretion
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04912 GnRH signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04921 Oxytocin signaling pathway
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04935 Growth hormone synthesis, secretion and action
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04924 Renin secretion
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04925 Aldosterone synthesis and secretion
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04927 Cortisol synthesis and secretion
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09153 Circulatory system
04260 Cardiac muscle contraction
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04261 Adrenergic signaling in cardiomyocytes
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04270 Vascular smooth muscle contraction
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09154 Digestive system
04973 Carbohydrate digestion and absorption
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09156 Nervous system
04724 Glutamatergic synapse
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04727 GABAergic synapse
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04725 Cholinergic synapse
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04728 Dopaminergic synapse
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04726 Serotonergic synapse
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04723 Retrograde endocannabinoid signaling
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09158 Development and regeneration
04361 Axon regeneration
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09159 Environmental adaptation
04713 Circadian entrainment
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09164 Neurodegenerative disease
05010 Alzheimer disease
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
05020 Prion disease
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
05022 Pathways of neurodegeneration - multiple diseases
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09165 Substance dependence
05031 Amphetamine addiction
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
05412 Arrhythmogenic right ventricular cardiomyopathy
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
05414 Dilated cardiomyopathy
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
04934 Cushing syndrome
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
Ion channels [BR:ko04040 ]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
K04851 CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
BRITE hierarchy
Authors
Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nurnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nurnberg P, Striessnig J, Bolz HJ
Authors
Seino S, Chen L, Seino M, Blondel O, Takeda J, Johnson JH, Bell GI