KEGG   ORTHOLOGY: K04853
Entry
K04853                      KO                                     
Symbol
CACNA1F, CAV1.4
Name
voltage-dependent calcium channel L type alpha-1F
Pathway
map04010  MAPK signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04260  Cardiac muscle contraction
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04723  Retrograde endocannabinoid signaling
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04727  GABAergic synapse
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04921  Oxytocin signaling pathway
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04929  GnRH secretion
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map05010  Alzheimer disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05207  Chemical carcinogenesis - receptor activation
map05410  Hypertrophic cardiomyopathy
map05412  Arrhythmogenic right ventricular cardiomyopathy
map05414  Dilated cardiomyopathy
Disease
H00481  Cone-rod dystrophy and cone dystrophy
H00690  Aland Island eye disease
H00787  Congenital stationary night blindness
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04020 Calcium signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04024 cAMP signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04022 cGMP-PKG signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04929 GnRH secretion
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04912 GnRH signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04921 Oxytocin signaling pathway
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04935 Growth hormone synthesis, secretion and action
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04924 Renin secretion
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04925 Aldosterone synthesis and secretion
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04927 Cortisol synthesis and secretion
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04261 Adrenergic signaling in cardiomyocytes
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04270 Vascular smooth muscle contraction
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
  09156 Nervous system
   04727 GABAergic synapse
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04725 Cholinergic synapse
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04726 Serotonergic synapse
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   04723 Retrograde endocannabinoid signaling
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   05020 Prion disease
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   05022 Pathways of neurodegeneration - multiple diseases
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
   05414 Dilated cardiomyopathy
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
Other DBs
GO: 0005245
TC: 1.A.1.11.11
Genes
HSA: 778(CACNA1F)
PTR: 740711(CACNA1F)
PPS: 100988624(CACNA1F)
GGO: 101131714(CACNA1F)
PON: 100431752(CACNA1F)
NLE: 100590475(CACNA1F)
MCC: 715787(CACNA1F)
MCF: 102119841(CACNA1F)
MTHB: 126945535
CSAB: 103231971(CACNA1F)
CATY: 105573107(CACNA1F)
PANU: 101019865(CACNA1F)
TGE: 112614995(CACNA1F)
RRO: 104661816(CACNA1F)
RBB: 108521361
TFN: 117077518(CACNA1F)
CJC: 100386041(CACNA1F)
SBQ: 101034685(CACNA1F)
CSYR: 103277252(CACNA1F)
MMUR: 105856433(CACNA1F)
LCAT: 123628833(CACNA1F)
OGA: 100962519(CACNA1F)
MMU: 54652(Cacna1f)
MCAL: 110286673(Cacna1f)
MPAH: 110313596(Cacna1f)
RNO: 114493(Cacna1f)
MCOC: 116102419(Cacna1f)
MUN: 110561910(Cacna1f)
CGE: 100757994(Cacna1f)
MAUA: 101830198(Cacna1f)
PLEU: 114701281(Cacna1f)
MFOT: 126512843
AAMP: 119804579(Cacna1f)
NGI: 103741673(Cacna1f)
HGL: 101722090(Cacna1f)
CPOC: 100720484(Cacna1f)
CCAN: 109697195(Cacna1f)
DORD: 105997824(Cacna1f)
DSP: 122098776(Cacna1f)
NCAR: 124971751
OCU: 100357261(CACNA1F)
OPI: 101519864(CACNA1F)
TUP: 102482779(CACNA1F)
CFA: 480915(CACNA1F)
CLUD: 112673110(CACNA1F)
VVP: 112907237(CACNA1F)
VLG: 121483414(CACNA1F)
AML: 100468661(CACNA1F)
UMR: 103667625(CACNA1F)
UAH: 113265950(CACNA1F)
UAR: 123797184(CACNA1F)
ELK: 111150407
LLV: 125091668
MPUF: 101689134(CACNA1F)
ORO: 101364481(CACNA1F)
EJU: 114216787(CACNA1F)
ZCA: 113931031(CACNA1F)
MLX: 118008972(CACNA1F)
NSU: 110570742(CACNA1F)
FCA: 101080870(CACNA1F)
PYU: 121026060(CACNA1F)
PBG: 122477612(CACNA1F)
LRUF: 124509536
PTG: 102950547(CACNA1F)
PPAD: 109248097(CACNA1F)
AJU: 106988999(CACNA1F)
HHV: 120221013(CACNA1F)
BTA: 509779(CACNA1F)
BOM: 102286805(CACNA1F)
BIU: 109554975(CACNA1F)
BBUB: 102407399(CACNA1F)
CHX: 102189746(CACNA1F)
OAS: 101104552(CACNA1F)
ODA: 120881638(CACNA1F)
CCAD: 122434769(CACNA1F)
SSC: 100514745(CACNA1F)
CFR: 102504151(CACNA1F)
CBAI: 105079415(CACNA1F)
CDK: 105103284(CACNA1F)
VPC: 102540844(CACNA1F)
BACU: 102998540(CACNA1F)
LVE: 103082192(CACNA1F)
OOR: 101281199(CACNA1F)
DLE: 111169490(CACNA1F)
PCAD: 102992313(CACNA1F)
PSIU: 116747382(CACNA1F)
ECB: 100062861(CACNA1F)
EPZ: 103543955(CACNA1F)
EAI: 106826963(CACNA1F)
MYB: 102260789(CACNA1F)
MYD: 102771414(CACNA1F)
MMYO: 118654729(CACNA1F)
MLF: 102434312(CACNA1F)
MNA: 107541372(CACNA1F)
PKL: 118731815(CACNA1F)
HAI: 109374806(CACNA1F)
DRO: 112322357(CACNA1F)
SHON: 118998346(CACNA1F)
AJM: 119059521(CACNA1F)
PDIC: 114505705(CACNA1F)
PHAS: 123832713(CACNA1F)
MMF: 118635608(CACNA1F)
RFQ: 117023033(CACNA1F)
PALE: 102893611(CACNA1F)
PGIG: 120587067(CACNA1F)
PVP: 105309056(CACNA1F)
RAY: 107514999(CACNA1F)
MJV: 108404213(CACNA1F)
TOD: 119246715(CACNA1F)
SARA: 101548753(CACNA1F)
LAV: 100674649(CACNA1F)
TMU: 101340818
DNM: 101421427(CACNA1F)
MDO: 100019531(CACNA1F)
SHR: 100927554(CACNA1F)
PCW: 110201034(CACNA1F)
OAA: 100075939(CACNA1F)
PCOC: 116240105(CACNA1F)
AFUL: 116501486
LSR: 110482322
PMOA: 120506954(CACNA1F)
OTC: 121339170(CACNA1F)
PRUF: 121362313
FAB: 101817703
PHI: 102111116(CACNA1F)
CCW: 120412196(CACNA1F)
CBRC: 103618144
FPG: 101922071
FCH: 102046341
CLV: 102089966
ACHC: 115338229(CACNA1F)
AAM: 106493905(CACNA1F)
AROW: 112972618
ASN: 102368804(CACNA1F)
AMJ: 102563169(CACNA1F)
CPIC: 101934179
CABI: 116823939
MRV: 120388192(CACNA1F)
ACS: 100565753(cacna1f)
PVT: 110078615(CACNA1F)
SUND: 121920504(CACNA1F)
PBI: 103051695(CACNA1F)
PMUR: 107284195(CACNA1F)
CTIG: 120311308(CACNA1F)
PGUT: 117675658(CACNA1F)
VKO: 123029960(CACNA1F)
PMUA: 114587594(CACNA1F)
ZVI: 118097569(CACNA1F)
GJA: 107117359
STOW: 125428467(CACNA1F)
XLA: 100462913(cacna1f.L)
XTR: 100485906(cacna1f)
NPR: 108788491
RTEM: 120913037(CACNA1F)
BBUF: 120977192(CACNA1F)
BGAR: 122919691(CACNA1F)
DRE: 559964(cacna1fb) 793708(cacna1fa)
PPRM: 120469151(cacna1fb) 120473866(cacna1fa)
MAMB: 125279615(cacna1fb) 125280153(cacna1fa)
IPU: 108265065(cacna1fb) 108265094(cacna1fa)
SMEO: 124399485(cacna1fa) 124399904(cacna1fb)
TFD: 113656188(cacna1fb) 113656253(cacna1fa)
EEE: 113578747(cacna1f) 113579098
TRU: 101077620(cacna1f) 101079199
CGOB: 115005436 115011426(cacna1f)
ELY: 117257982(cacna1fb) 117258407(cacna1fa)
EFO: 125891630(cacna1fa) 125891672(cacna1fb)
PLEP: 121946427
SLUC: 116043571(cacna1fa) 116045489(cacna1fb)
ECRA: 117947003(cacna1fa)
ESP: 116692878
PFLV: 114558250
GAT: 120814961(cacna1fb) 120828763(cacna1fa)
PPUG: 119222360(cacna1fb) 119223125(cacna1fa)
MSAM: 119905055(cacna1fb) 119905094(cacna1fa)
CUD: 121516935(cacna1fa) 121517368(cacna1fb)
ALAT: 119022437(cacna1fa) 119023017(cacna1fb)
MZE: 101480057
OAU: 116319501(cacna1fa) 116335447(cacna1fb)
OML: 112158663(cacna1fb) 112158801(cacna1fa)
PFOR: 103131960 103131961 103139061(cacna1f)
PLAI: 106935811 106942295 106954626(cacna1f)
PMEI: 106909745 106915898(cacna1f)
GAF: 122819169(cacna1fa) 122841771(cacna1fb)
CVG: 107095949(cacna1f) 107099706
CTUL: 119792002(cacna1fb) 119799513(cacna1fa)
GMU: 124867625(cacna1fa) 124868417(cacna1fb)
NFU: 107390498(cacna1f) 107391407
ALIM: 106519282(cacna1f) 106523414 106533880
NWH: 119417562
AOCE: 111580242
MCEP: 125000377(cacna1fa) 125008328(cacna1fb)
CSEM: 103384398 103385395(cacna1f)
SSEN: 122776983(cacna1fb) 122777519(cacna1fa)
HHIP: 117764489(cacna1fa) 117765247(cacna1fb)
HSP: 118111156(cacna1fb) 118111219(cacna1fa)
LCF: 108882181(cacna1fa) 108890565(cacna1fb)
XGL: 120803456(cacna1fa) 120804054(cacna1fb)
HCQ: 109510493 109512986(cacna1f)
BPEC: 110154433 110164475(cacna1f)
MALB: 109953071
BSPL: 114858189(cacna1fb) 114858500(cacna1fa)
SASA: 106572493
OTW: 112221526
OMY: 110512770(cacna1fb) 110531219
OGO: 124032106 124032399(cacna1fb) 124045931
SALP: 111966955
SNH: 120061553
CCLU: 121537216 121538138(cacna1fb) 121546475
AANG: 118207210(cacna1fb) 118210606
PSPA: 121305498
ARUT: 117967960
LCM: 102353236(CACNA1F)
 » show all
Reference
  Authors
Lee A, Wang S, Williams B, Hagen J, Scheetz TE, Haeseleer F
  Title
Characterization of Cav1.4 complexes (alpha11.4, beta2, and alpha2delta4) in HEK293T cells and in the retina.
  Journal
J Biol Chem 290:1505-21 (2015)
DOI:10.1074/jbc.M114.607465
  Sequence
[hsa:778]
Reference
PMID:9662399
  Authors
Strom TM, Nyakatura G, Apfelstedt-Sylla E, Hellebrand H, Lorenz B, Weber BH, Wutz K, Gutwillinger N, Ruther K, Drescher B, Sauer C, Zrenner E, Meitinger T, Rosenthal A, Meindl A
  Title
An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness.
  Journal
Nat Genet 19:260-3 (1998)
DOI:10.1038/940
  Sequence
[hsa:778]
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