KEGG   ORTHOLOGY: K04958
Entry
K04958                      KO                                     
Symbol
ITPR1
Name
inositol 1,4,5-triphosphate receptor type 1
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04070  Phosphatidylinositol signaling system
map04114  Oocyte meiosis
map04140  Autophagy - animal
map04210  Apoptosis
map04218  Cellular senescence
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04540  Gap junction
map04611  Platelet activation
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04713  Circadian entrainment
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04745  Phototransduction - fly
map04750  Inflammatory mediator regulation of TRP channels
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map05010  Alzheimer disease
map05012  Parkinson disease
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05205  Proteoglycans in cancer
map05417  Lipid and atherosclerosis
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04020 Calcium signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04070 Phosphatidylinositol signaling system
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04022 cGMP-PKG signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04210 Apoptosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04218 Cellular senescence
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04621 NOD-like receptor signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04625 C-type lectin receptor signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04929 GnRH secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04912 GnRH signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04915 Estrogen signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04921 Oxytocin signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04935 Growth hormone synthesis, secretion and action
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04918 Thyroid hormone synthesis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04928 Parathyroid hormone synthesis, secretion and action
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04924 Renin secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04925 Aldosterone synthesis and secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04927 Cortisol synthesis and secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09154 Digestive system
   04970 Salivary secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04971 Gastric acid secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04972 Pancreatic secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09156 Nervous system
   04724 Glutamatergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04725 Cholinergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04728 Dopaminergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04726 Serotonergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04720 Long-term potentiation
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04730 Long-term depression
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04723 Retrograde endocannabinoid signaling
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09157 Sensory system
   04745 Phototransduction - fly
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04750 Inflammatory mediator regulation of TRP channels
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05163 Human cytomegalovirus infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05012 Parkinson disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05016 Huntington disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05017 Spinocerebellar ataxia
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05020 Prion disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05022 Pathways of neurodegeneration - multiple diseases
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3708(ITPR1)
PTR: 460134(ITPR1)
PPS: 100984884(ITPR1)
GGO: 101151145(ITPR1)
PON: 100445922(ITPR1)
NLE: 100587159(ITPR1)
HMH: 116466681(ITPR1)
MCC: 703669(ITPR1)
MCF: 101865389(ITPR1)
MTHB: 126947659
MNI: 105477623(ITPR1)
CSAB: 103227941(ITPR1)
CATY: 105585726(ITPR1)
PANU: 101017317(ITPR1)
TGE: 112618470(ITPR1)
MLEU: 105528641(ITPR1)
RRO: 104664252(ITPR1)
RBB: 108528737(ITPR1)
TFN: 117083173(ITPR1)
PTEH: 111546970(ITPR1)
CANG: 105508383(ITPR1)
CJC: 100385763(ITPR1)
SBQ: 101029556(ITPR1)
CIMI: 108292033(ITPR1)
CSYR: 103256992
MMUR: 105869384(ITPR1)
LCAT: 123623574(ITPR1)
PCOQ: 105812706(ITPR1)
OGA: 100964437(ITPR1)
MMU: 16438(Itpr1)
MCAL: 110296867(Itpr1)
MPAH: 110317210(Itpr1)
RNO: 25262(Itpr1)
MCOC: 116099362(Itpr1)
ANU: 117714720(Itpr1)
MUN: 110552142(Itpr1)
CGE: 100764450(Itpr1)
MAUA: 101836776(Itpr1)
PROB: 127236214(Itpr1)
PLEU: 114691978(Itpr1)
MORG: 121440758(Itpr1)
MFOT: 126490074
AAMP: 119806390(Itpr1)
NGI: 103751203(Itpr1)
HGL: 101706047(Itpr1)
CPOC: 100713023(Itpr1)
CCAN: 109699340(Itpr1)
DORD: 105981338(Itpr1)
DSP: 122108136(Itpr1)
PLOP: 125358763(Itpr1)
NCAR: 124970932
OCU: 100009505
OPI: 101524859(ITPR1)
TUP: 102473622(ITPR1)
GVR: 103598637(ITPR1)
CFA: 476548(ITPR1)
CLUD: 112662581(ITPR1)
VVP: 112913302(ITPR1)
VLG: 121495032(ITPR1)
NPO: 129521608(ITPR1)
AML: 100467161(ITPR1)
UMR: 103669597(ITPR1)
UAH: 113257114(ITPR1)
UAR: 123799165(ITPR1)
ELK: 111144005
LLV: 125109360
MPUF: 101677799(ITPR1)
MNP: 132011514(ITPR1)
NVS: 122909251(ITPR1)
ORO: 101367743(ITPR1)
EJU: 114207665(ITPR1)
ZCA: 113918169(ITPR1)
MLX: 118005236(ITPR1)
NSU: 110584934(ITPR1)
LWW: 102739407
FCA: 101100546(ITPR1)
PYU: 121041326(ITPR1)
PCOO: 112858201(ITPR1)
PBG: 122487457(ITPR1)
LRUF: 124522957
PTG: 102963245(ITPR1)
PPAD: 109254652(ITPR1)
PUC: 125929585
AJU: 106978946
HHV: 120237135(ITPR1)
BTA: 317697(ITPR1)
BOM: 102269088(ITPR1)
BIU: 109576135(ITPR1)
BBUB: 102412452(ITPR1)
BBIS: 104991589(ITPR1)
CHX: 102188092(ITPR1)
OAS: 101108864(ITPR1)
BTAX: 128046429(ITPR1)
ODA: 120867669(ITPR1)
CCAD: 122424343(ITPR1)
MBEZ: 129548039(ITPR1)
SSC: 397454(ITPR1)
CFR: 102521814(ITPR1)
CBAI: 105074761(ITPR1)
CDK: 105093156(ITPR1)
VPC: 102535688(ITPR1)
BACU: 103010644(ITPR1)
LVE: 103079294(ITPR1)
OOR: 101282737(ITPR1)
DLE: 111174169(ITPR1)
PSIU: 116761601(ITPR1)
NASI: 112400978(ITPR1)
ECB: 100052808(ITPR1)
EPZ: 103550297(ITPR1)
EAI: 106848450(ITPR1)
MYB: 102262150(ITPR1)
MYD: 102755292(ITPR1)
MMYO: 118668410(ITPR1)
MNA: 107529142(ITPR1)
PKL: 118715601(ITPR1)
EFUS: 103300420(ITPR1)
HAI: 109395800(ITPR1)
DRO: 112309625(ITPR1)
SHON: 118989408(ITPR1)
AJM: 119036740(ITPR1)
PDIC: 114501461(ITPR1)
PHAS: 123830469(ITPR1)
MMF: 118632878(ITPR1)
RFQ: 117037173(ITPR1)
PALE: 102894982(ITPR1)
PGIG: 120582429(ITPR1)
PVP: 105295171(ITPR1)
RAY: 107504134(ITPR1)
MJV: 108395952(ITPR1)
TOD: 119255045(ITPR1)
SARA: 101556467(ITPR1)
LAV: 100665028(ITPR1)
TMU: 101346534
ETF: 101654141(ITPR1)
DNM: 101429543(ITPR1)
MDO: 100013305(ITPR1)
GAS: 123247136(ITPR1)
SHR: 100918532(ITPR1)
AFZ: 127551451
PCW: 110195613(ITPR1)
OAA: 100075749(ITPR1)
GGA: 395412(ITPR1)
PCOC: 116236726(ITPR1)
MGP: 100540293(ITPR1)
CJO: 107319899(ITPR1)
TPAI: 128078344(ITPR1)
LMUT: 125698895(ITPR1)
NMEL: 110404652(ITPR1)
APLA: 101791594(ITPR1)
ACYG: 106036713(ITPR1)
CATA: 118248096(ITPR1)
AFUL: 116492888(ITPR1)
TGU: 100229045(ITPR1)
LSR: 110469846(ITPR1)
SCAN: 103823703(ITPR1)
PMOA: 120513991(ITPR1)
OTC: 121347122(ITPR1)
PRUF: 121350549(ITPR1)
GFR: 102045318(ITPR1)
FAB: 101816592(ITPR1)
OMA: 130258144(ITPR1)
PHI: 102107950(ITPR1)
PMAJ: 107210255(ITPR1)
CCAE: 111934931(ITPR1)
CCW: 104683516(ITPR1)
CBRC: 103616302(ITPR1)
ETL: 114062422(ITPR1)
ZAB: 102074964(ITPR1)
ACHL: 103800315
SVG: 106851697(ITPR1)
MMEA: 130583956(ITPR1)
HRT: 120758348(ITPR1)
FPG: 101916606(ITPR1)
FCH: 102050701(ITPR1)
CLV: 102095848(ITPR1)
EGZ: 104132649(ITPR1)
NNI: 104016945(ITPR1)
PCRI: 104037068(ITPR1)
PLET: 104619233(ITPR1)
EHS: 104515727(ITPR1)
PCAO: 104042825(ITPR1)
ACUN: 113484753(ITPR1)
TALA: 104364086(ITPR1)
PADL: 103922482(ITPR1)
AFOR: 103902541(ITPR1)
ACHC: 115353680(ITPR1)
HALD: 104322104(ITPR1)
HLE: 104833622(ITPR1)
AGEN: 126049978
GCL: 127021758
CCRI: 104159719(ITPR1)
CSTI: 104561079(ITPR1)
CMAC: 104487041(ITPR1)
MUI: 104540768(ITPR1)
BREG: 104640667(ITPR1)
FGA: 104077337(ITPR1)
GSTE: 104253546(ITPR1)
LDI: 104349675
OHA: 104338381(ITPR1)
NNT: 104407157(ITPR1)
SHAB: 115614357(ITPR1)
DPUB: 104309249(ITPR1)
PGUU: 104472200(ITPR1)
ACAR: 104523042
CPEA: 104393852(ITPR1)
CVF: 104284516(ITPR1)
RTD: 128915541(ITPR1)
CUCA: 104063584(ITPR1)
TEO: 104377352(ITPR1)
AAM: 106489801(ITPR1)
AROW: 112970422(ITPR1)
NPD: 112944112(ITPR1)
TGT: 104575057(ITPR1)
DNE: 112989449(ITPR1)
SCAM: 104153263(ITPR1)
ASN: 102379206(ITPR1)
AMJ: 102561752(ITPR1)
CPOO: 109311155(ITPR1)
GGN: 109288949(ITPR1)
PSS: 102462538(ITPR1)
CMY: 102941719(ITPR1)
CCAY: 125639566(ITPR1)
DCC: 119858255(ITPR1)
CPIC: 101945436(ITPR1)
TST: 117881069(ITPR1)
CABI: 116827043(ITPR1)
MRV: 120409030(ITPR1)
ACS: 100568038(itpr1)
PVT: 110088203(ITPR1)
SUND: 121921093(ITPR1)
PBI: 103049895
PMUR: 107293430(ITPR1)
CTIG: 120304039(ITPR1)
PGUT: 117673926(ITPR1)
APRI: 131190910(ITPR1)
PTEX: 113451193(ITPR1)
NSS: 113419479(ITPR1)
VKO: 123034368(ITPR1)
PMUA: 114591812(ITPR1)
PRAF: 128408441(ITPR1)
ZVI: 118080803(ITPR1)
HCG: 128345171(ITPR1)
GJA: 107116811(ITPR1)
STOW: 125428321(ITPR1)
EMC: 129327369(ITPR1)
XLA: 108714625 399254(itpr1.S)
XTR: 100493341(itpr1)
NPR: 108791910(ITPR1)
RTEM: 120944895(ITPR1)
BBUF: 120979744(ITPR1)
BGAR: 122943343(ITPR1)
MUO: 115472325(ITPR1)
GSH: 117351055(ITPR1)
DRE: 100149388(itpr1b) 567611(itpr1a)
PTET: 122346545 122347296(itpr1a) 122354376(itpr1b)
LROH: 127166842(itpr1a) 127172757(itpr1b)
OMC: 131541884(itpr1a) 131548898(itpr1b)
PPRM: 120480404(itpr1b) 120491693(itpr1a)
MAMB: 125256994(itpr1b) 125273734(itpr1a)
TROS: 130556672(itpr1a) 130571421(itpr1b)
MANU: 129427091(itpr1b) 129450757(itpr1a)
IPU: 108254919(itpr1b) 108271603(itpr1a)
IFU: 128614771(itpr1a) 128624999(itpr1b)
PHYP: 113539752(itpr1) 113545832
SMEO: 124382911 124402041(itpr1b)
TFD: 113647180(itpr1b) 113651639(itpr1a)
AMEX: 103030168 103040877(itpr1)
CMAO: 118799312(itpr1b) 118808278(itpr1a)
EEE: 113575990
CHAR: 105900774(itpr1a) 105909947(itpr1b)
TFS: 130524771(itpr1a) 130524856(itpr1b)
LCO: 104921973(itpr1) 104931270
NCC: 104955082(itpr1)
CGOB: 115008879(itpr1) 115008910
ELY: 117256214 117257450(itpr1b)
EFO: 125891973(itpr1b) 125898002
PLEP: 121952371(itpr1b) 121952968
SLUC: 116036270(itpr1b) 116065778
ECRA: 117942774 117942903(itpr1b)
GAT: 120835398 120835789(itpr1b)
PPUG: 119194315 119229493(itpr1b)
AFB: 129105846 129106149(itpr1b)
CLUM: 117730310(itpr1b) 117731168
SCHU: 122861809(itpr1b) 122869241
CUD: 121506856 121507377(itpr1b)
ALAT: 119020522 119021190(itpr1b)
OAU: 116313940(itpr1b) 116326605
OML: 112144868 112145415(itpr1b)
XMA: 102217419 102227088(itpr1)
XCO: 114135479 114136183(itpr1)
XHE: 116710459
PFOR: 103147315 103147632(itpr1)
PLAI: 106936350 106950616(itpr1)
PMEI: 106908051 106932289(itpr1)
GAF: 122833721(itpr1b) 122833870
CTUL: 119785392 119786603(itpr1b)
GMU: 124856653(itpr1b) 124856805
NFU: 107384050 107385796(itpr1)
KMR: 108235741(itpr1a) 108244393(itpr1b)
AOCE: 111569665 111575102(itpr1)
CSEM: 103385989(itpr1) 103386616
SSEN: 122768001(itpr1b) 122768475
HHIP: 117761880 117762136(itpr1b)
HSP: 118104834(itpr1b) 118105042
XGL: 120807463 120807595(itpr1b)
HCQ: 109521562(itpr1) 109522343
BSPL: 114855079(itpr1b) 114856386(itpr1a)
PKI: 111839848 111840603(itpr1)
AANG: 118207405 118211513(itpr1b)
LOC: 102694604(itpr1)
PSPA: 121298161(itpr1b) 121328701
ARUT: 117411749(itpr1a) 117412304
PSEX: 120540181
LCM: 102361301(ITPR1)
CMK: 103185072(itpr1b)
CPLA: 122559178(itpr1b)
LERI: 129704553(itpr1b)
BFO: 118415973
BBEL: 109477077
CIN: 101243127
SPU: 594527
LPIC: 129255730
AJC: 117111734
DME: Dmel_CG1063(Itpr)
DER: 6552808
DSE: 6620843
DSI: Dsimw501_GD19791(Dsim_GD19791)
DAN: 6500042
DSR: 110177231
DPO: 4802432
DPE: 6591340
DMN: 108155501
DWI: 6642428
DGR: 6563891
DNV: 108655982
DVI: 6630671
CCAT: 101453862
BOD: 106618098
TDA: 119682515
MDE: 101897637
SCAC: 106090477
LCQ: 111689930
LSQ: 119606130
ECOE: 129942465
HIS: 119661016
ACOZ: 120947347
AARA: 120898302
AMER: 121591372
ASTE: 118509618
AFUN: 125771665
AALI: 118464269
AAG: 5564815
CPII: 120412372
CNS: 116349136
BCOO: 119073232
ACER: 107996814
ALAB: 122720631
ADR: 102672413
AFLR: 100870897
BIM: 100747875
BBIF: 117206478
BVK: 117234765
BVAN: 117159743
BTER: 100643559
BAFF: 126918435
BPYO: 122577819
FVI: 122526888
OBB: 114870929
MGEN: 117229669
NMEA: 116431679
CGIG: 122397729
SOC: 105196704
MPHA: 105835203
AEC: 105143165
ACEP: 105623125
PBAR: 105425708
VEM: 105563305
HST: 105190557
DQU: 106750778
CFO: 105255588
FEX: 115239539
LHU: 105670881
PGC: 109851819
OBO: 105286972
PCF: 106785965
PFUC: 122518409
VPS: 122632650
VCRB: 124427667
NVI: 100123596
CSOL: 105359496
TPRE: 106659907
LHT: 122497972
LBD: 127282473
MDL: 103576554
CGLO: 123259822
FAS: 105268906
DAM: 107041404
AGIF: 122851612
CINS: 118065772
VCAN: 122414157
CCIN: 107274736
DSM: 124411612
NPT: 124218647
NFB: 124182066
NLO: 107228096
NVG: 124304355
TCA: 660517
DPA: 109537933
SOY: 115876815
AGRG: 126748996
ATD: 109601088
CSET: 123322119
AGB: 108906811
NVL: 108565321
APLN: 108733799
PPYR: 116165382
OTU: 111425531
BMOR: 101741421
BANY: 112056286
MJU: 123877448
NIQ: 126777789
VCD: 124540578
MCIX: 123666556
PMAC: 106719904
PPOT: 106111363
PXU: 106123130
PRAP: 110993872
PBX: 123715822
PNAP: 125057148
ZCE: 119837686
CCRC: 123703602
HAW: 110375060
HZE: 124642746
TNL: 113498357
SLIU: 111364442
OFU: 114351997
PXY: 105395447
PGW: 126377795
CFEL: 113378547
CCRN: 123302680
API: 100163622
DNX: 107168497
RMD: 113559923
ACOO: 126836344
BTAB: 109031884
DCI: 103507937
CLEC: 106663307
HHAL: 106689508
NLU: 111047153
HVI: 124368672
FOC: 113210326
TPAL: 117644439
ZNE: 110831932
CSEC: 111865978
SGRE: 126297631
IEL: 124171669
DMK: 116926731
DPZ: 124315091
PVM: 113805298
PCHN: 125039253
PMOO: 119586318
HAME: 121871416
PCLA: 123753965
CQD: 128687473
PTRU: 123504386
ESN: 127006977
HAZT: 108666338
EAF: 111712266
LSM: 121128736
PPOI: 119113092
DSV: 119461957
RSAN: 119396910
RMP: 119174993
VDE: 111248117
VJA: 111259781
DFR: 124500132
PTEP: 107439907
UDV: 129230091
SDM: 118184098
LPOL: 106459878
PMEO: 129588179
CEL: CELE_F33D4.2(itr-1)
CBR: CBG_05938(Cbr-itr-1)
TSP: Tsp_10834
BGT: 106056031
GAE: 121367544
HRF: 124124191
HRJ: 124278749
CRG: 105325881
CVN: 111106119
CANU: 128157813
OED: 125655497
MYI: 110460372
PMAX: 117330316
MCAF: 127701548
MMER: 128547932
DPOL: 127861130
OBI: 106882671
OSN: 115222534
NVE: 5509439
ATEN: 116304295
SPIS: 111326463
XEN: 124445677
HMG: 100202979
HSY: 130655305
 » show all
Reference
PMID:2554142
  Authors
Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N, Mikoshiba K
  Title
Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.
  Journal
Nature 342:32-8 (1989)
DOI:10.1038/342032a0
  Sequence
[mmu:16438]
LinkDB

KEGG   ORTHOLOGY: K04959
Entry
K04959                      KO                                     
Symbol
ITPR2
Name
inositol 1,4,5-triphosphate receptor type 2
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04070  Phosphatidylinositol signaling system
map04114  Oocyte meiosis
map04210  Apoptosis
map04218  Cellular senescence
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04540  Gap junction
map04611  Platelet activation
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04750  Inflammatory mediator regulation of TRP channels
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map05010  Alzheimer disease
map05012  Parkinson disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05205  Proteoglycans in cancer
Disease
H02281  Isolated anhidrosis with normal sweat glands
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04020 Calcium signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04070 Phosphatidylinositol signaling system
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04022 cGMP-PKG signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04210 Apoptosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04218 Cellular senescence
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04621 NOD-like receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04625 C-type lectin receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04929 GnRH secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04912 GnRH signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04915 Estrogen signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04921 Oxytocin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04935 Growth hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04918 Thyroid hormone synthesis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04928 Parathyroid hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04924 Renin secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04925 Aldosterone synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04927 Cortisol synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09154 Digestive system
   04970 Salivary secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04971 Gastric acid secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04972 Pancreatic secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09156 Nervous system
   04724 Glutamatergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04725 Cholinergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04728 Dopaminergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04726 Serotonergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04720 Long-term potentiation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04730 Long-term depression
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04723 Retrograde endocannabinoid signaling
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05163 Human cytomegalovirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05012 Parkinson disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05017 Spinocerebellar ataxia
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05020 Prion disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05022 Pathways of neurodegeneration - multiple diseases
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3709(ITPR2)
PTR: 473389(ITPR2)
PPS: 100980378(ITPR2)
GGO: 101151502(ITPR2)
PON: 100434318(ITPR2)
NLE: 100599135(ITPR2)
HMH: 116472793(ITPR2)
MCC: 708714(ITPR2)
MCF: 102115744(ITPR2)
MTHB: 126930046
MNI: 105492154(ITPR2)
CSAB: 103218776(ITPR2)
CATY: 105601409(ITPR2)
PANU: 101023200(ITPR2)
TGE: 112634518(ITPR2)
MLEU: 105555461(ITPR2)
RRO: 104675331(ITPR2)
RBB: 108523739(ITPR2)
TFN: 117090367(ITPR2)
PTEH: 111540617(ITPR2)
CANG: 105515211(ITPR2)
CJC: 118144170(ITPR2)
SBQ: 101049881(ITPR2)
CIMI: 108288162(ITPR2)
CSYR: 103261167(ITPR2)
MMUR: 105857276(ITPR2)
LCAT: 123639915(ITPR2)
PCOQ: 105807599(ITPR2)
OGA: 100954512(ITPR2)
MMU: 16439(Itpr2)
MCAL: 110295833(Itpr2)
MPAH: 110317251(Itpr2)
RNO: 81678(Itpr2)
MCOC: 116099798(Itpr2)
ANU: 117714743(Itpr2)
MUN: 110558908(Itpr2)
CGE: 100758965(Itpr2)
MAUA: 101835945(Itpr2)
PROB: 127213143(Itpr2)
PLEU: 114708393(Itpr2)
MORG: 121433763(Itpr2)
MFOT: 126515231
AAMP: 119806213(Itpr2)
HGL: 101716022(Itpr2)
CPOC: 100717278(Itpr2)
DORD: 106001099(Itpr2)
DSP: 122100994(Itpr2)
PLOP: 125342841(Itpr2)
NCAR: 124983533
OCU: 100356806
OPI: 101526097(ITPR2)
TUP: 102482868(ITPR2)
CFA: 486628(ITPR2)
CLUD: 112665544(ITPR2)
VVP: 112917203(ITPR2)
VLG: 121479635(ITPR2)
NPO: 129505465(ITPR2)
AML: 100477888(ITPR2)
UMR: 103665275(ITPR2)
UAH: 113257782(ITPR2)
UAR: 123801684(ITPR2)
ELK: 111159979
LLV: 125107116
MPUF: 101684131(ITPR2)
MNP: 132019550(ITPR2)
NVS: 122891087(ITPR2)
ORO: 101377380(ITPR2)
EJU: 114216613(ITPR2)
ZCA: 113921922(ITPR2)
MLX: 118025560(ITPR2)
NSU: 110580957(ITPR2)
LWW: 102735685(ITPR2)
FCA: 101101230(ITPR2)
PYU: 121038795(ITPR2)
PCOO: 112867360(ITPR2)
PBG: 122472170(ITPR2)
LRUF: 124501326
PTG: 102971840(ITPR2)
PPAD: 109268756(ITPR2)
PUC: 125920161
AJU: 106968786
HHV: 120237482(ITPR2)
BTA: 281878(ITPR2)
BOM: 102269013(ITPR2)
BIU: 109558547(ITPR2)
BBUB: 102401062(ITPR2)
BBIS: 105000232(ITPR2)
CHX: 102170858(ITPR2)
OAS: 101113317(ITPR2)
BTAX: 128048527(ITPR2)
ODA: 120858499(ITPR2)
CCAD: 122423671(ITPR2)
MBEZ: 129536224(ITPR2)
SSC: 100517279(ITPR2)
CFR: 102517295(ITPR2)
CBAI: 105062304(ITPR2)
CDK: 105102013(ITPR2)
VPC: 102529461(ITPR2)
BACU: 103018280(ITPR2)
LVE: 103078697(ITPR2)
OOR: 101281155(ITPR2)
DLE: 111176861(ITPR2)
PCAD: 102984842(ITPR2)
PSIU: 116760890(ITPR2)
NASI: 112391770(ITPR2)
ECB: 100064557(ITPR2)
EPZ: 103546630(ITPR2) 103548182
EAI: 106834887(ITPR2)
MYB: 102256216(ITPR2)
MMYO: 118652119(ITPR2)
MLF: 102422734(ITPR2)
MNA: 107525255(ITPR2)
PKL: 118730836(ITPR2)
EFUS: 103285158(ITPR2)
HAI: 109372316
DRO: 112318382(ITPR2)
SHON: 118978442(ITPR2)
AJM: 119048995(ITPR2)
PDIC: 114513086(ITPR2)
PHAS: 123812354(ITPR2)
MMF: 118623451(ITPR2)
RFQ: 117028439(ITPR2)
PALE: 102896356(ITPR2)
PGIG: 120618337(ITPR2)
PVP: 105294112(ITPR2)
RAY: 107497427(ITPR2)
MJV: 108403293(ITPR2)
TOD: 119247621(ITPR2)
SARA: 101556630(ITPR2)
LAV: 100667845(ITPR2)
TMU: 101356404
ETF: 101638553(ITPR2)
DNM: 101423325(ITPR2)
MDO: 100010212(ITPR2)
GAS: 123250011(ITPR2)
SHR: 100921270(ITPR2)
AFZ: 127539174
PCW: 110193334(ITPR2)
OAA: 103164954(ITPR2)
GGA: 418212(ITPR2)
PCOC: 116231423(ITPR2)
MGP: 100551445(ITPR2)
CJO: 107316928(ITPR2)
TPAI: 128084490(ITPR2)
LMUT: 125688029(ITPR2)
NMEL: 110396437(ITPR2)
APLA: 101791934(ITPR2)
ACYG: 106038242
CATA: 118245143(ITPR2)
AFUL: 116488562(ITPR2)
TGU: 100230706(ITPR2)
LSR: 110474888(ITPR2)
SCAN: 103819592(ITPR2)
PMOA: 120501588(ITPR2)
OTC: 121332088(ITPR2)
PRUF: 121354266(ITPR2)
GFR: 102036319(ITPR2)
FAB: 101811180(ITPR2)
OMA: 130265231(ITPR2)
PHI: 102112318(ITPR2)
PMAJ: 107204618(ITPR2)
CCAE: 111930014(ITPR2)
CCW: 104696157(ITPR2)
CBRC: 103623356(ITPR2)
ETL: 114064981(ITPR2)
ZAB: 102062691(ITPR2)
ACHL: 103805612
SVG: 106860950(ITPR2)
MMEA: 130576119(ITPR2)
HRT: 120751508(ITPR2)
FPG: 101920370
FCH: 102052635(ITPR2)
CLV: 102096683(ITPR2)
EGZ: 104135140(ITPR2)
NNI: 104012694(ITPR2)
PCRI: 104029680
PCAO: 104053012
ACUN: 113489114(ITPR2)
TALA: 104360363(ITPR2)
PADL: 103924320(ITPR2)
AFOR: 103898700(ITPR2)
ACHC: 115352454(ITPR2)
HALD: 104315324(ITPR2)
HLE: 104836698(ITPR2)
AGEN: 126047976
GCL: 127029777
CMAC: 104481042
MUI: 104547733(ITPR2)
BREG: 104641733(ITPR2)
GSTE: 104257964(ITPR2)
OHA: 104335261(ITPR2)
NNT: 104401715
SHAB: 115604669(ITPR2)
DPUB: 104305160(ITPR2)
PGUU: 104469213
CPEA: 104394556(ITPR2)
CVF: 104281650(ITPR2)
RTD: 128904284(ITPR2)
CUCA: 104067151(ITPR2)
TEO: 104374801
AAM: 106488657
AROW: 112966593(ITPR2)
NPD: 112950663(ITPR2)
DNE: 112991504(ITPR2)
SCAM: 104154123(ITPR2)
ASN: 102379727
AMJ: 102570264(ITPR2)
CPOO: 109316376(ITPR2)
GGN: 109296316(ITPR2)
PSS: 102453428(ITPR2)
CMY: 102942754(ITPR2)
CCAY: 125624778(ITPR2)
DCC: 119850635(ITPR2)
CPIC: 101931123(ITPR2)
TST: 117883546(ITPR2)
CABI: 116817304(ITPR2)
MRV: 120407194(ITPR2)
ACS: 100567982(itpr2)
PVT: 110081241(ITPR2)
SUND: 121932190(ITPR2)
PBI: 103058322
PMUR: 107296465(ITPR2)
CTIG: 120314459(ITPR2)
PGUT: 117668319(ITPR2)
APRI: 131201668(ITPR2)
PTEX: 113436405(ITPR2)
NSS: 113412319(ITPR2)
VKO: 123019935(ITPR2)
PMUA: 114604922(ITPR2)
PRAF: 128421863(ITPR2)
ZVI: 118091007(ITPR2)
HCG: 128326332(ITPR2)
GJA: 107125949(ITPR2)
STOW: 125434869(ITPR2)
EMC: 129335399(ITPR2)
XLA: 108710178
XTR: 100124748(itpr2)
NPR: 108786728(ITPR2)
RTEM: 120932834(ITPR2)
BBUF: 121003741(ITPR2)
BGAR: 122928526(ITPR2)
MUO: 115477466
GSH: 117363742(ITPR2)
DRE: 562585(itpr2)
SRX: 107730567(itpr2) 107740421
SGH: 107553933(itpr2) 107583890
CAUA: 113061517 113118284(itpr2)
PTET: 122362645
LROH: 127180437(itpr2)
OMC: 131524125(itpr2)
PPRM: 120462004(itpr2)
MAMB: 125254454(itpr2)
CIDE: 127499474
TROS: 130562404(itpr2)
MANU: 129418804(itpr2)
IPU: 108264307
IFU: 128606629(itpr2)
PHYP: 113534384(itpr2)
SMEO: 124396223(itpr2)
TFD: 113652405(itpr2)
AMEX: 103025600
CMAO: 118818001(itpr2)
EEE: 113590571
CHAR: 105898040(itpr2)
TRU: 101063873(itpr2)
TFS: 130536793(itpr2)
LCO: 104924371(itpr2)
NCC: 104954420
CGOB: 115009269(itpr2)
ELY: 117261747(itpr2)
EFO: 125887046(itpr2)
PLEP: 121950593(itpr2)
SLUC: 116062267(itpr2)
ECRA: 117949271(itpr2)
ESP: 116694480(itpr2)
PFLV: 114559590(itpr2)
GAT: 120808946(itpr2) 120812471
PPUG: 119196688(itpr2)
AFB: 129108800(itpr2)
CLUM: 117732901(itpr2)
MSAM: 119893420(itpr2)
SCHU: 122875567(itpr2)
CUD: 121514503(itpr2)
ALAT: 119024134(itpr2)
MZE: 101466928(itpr2)
ONL: 100690527(itpr2)
OAU: 116335542(itpr2)
OLA: 101155191(itpr2)
OML: 112152271(itpr2)
XMA: 102220160(itpr2)
XCO: 114157038(itpr2)
XHE: 116733729(itpr2) 116736269
PRET: 103466096(itpr2)
PFOR: 103133680(itpr2)
PLAI: 106950914(itpr2)
PMEI: 106916046(itpr2)
GAF: 122835154(itpr2)
CVG: 107104059(itpr2)
CTUL: 119792990(itpr2)
GMU: 124858594(itpr2)
NFU: 107388954(itpr2)
KMR: 108239960(itpr2)
ALIM: 106515612(itpr2)
NWH: 119416249(itpr2)
AOCE: 111568340(itpr2)
MCEP: 125015051(itpr2)
CSEM: 103380150(itpr2)
POV: 109624047(itpr2)
SSEN: 122775623(itpr2)
HHIP: 117763343(itpr2)
HSP: 118109898(itpr2)
LCF: 108875355
SDU: 111228375(itpr2)
SLAL: 111655344(itpr2)
XGL: 120792799(itpr2)
HCQ: 109530334(itpr2)
SSCV: 125971286
BPEC: 110165611
MALB: 109970756(itpr2)
BSPL: 114857939(itpr2)
SASA: 100196824(itpr2) 106573309
SNH: 120054057(itpr2) 120065919
ELS: 105022141(itpr2)
SFM: 108942564(itpr2)
PKI: 111845672(itpr2)
AANG: 118219247(itpr2)
LOC: 102683319(itpr2)
PSEX: 120534185(itpr2)
LCM: 102359880(ITPR2)
CMK: 103188869(itpr2)
RTP: 109918007(itpr2)
CPLA: 122561564(itpr2)
LERI: 129707658(itpr2)
 » show all
Reference
  Authors
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
  Title
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
  Journal
J Biol Chem 280:10305-17 (2005)
DOI:10.1074/jbc.M413824200
  Sequence
[mmu:16439]
LinkDB

KEGG   ORTHOLOGY: K04960
Entry
K04960                      KO                                     
Symbol
ITPR3
Name
inositol 1,4,5-triphosphate receptor type 3
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04070  Phosphatidylinositol signaling system
map04114  Oocyte meiosis
map04210  Apoptosis
map04218  Cellular senescence
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04540  Gap junction
map04611  Platelet activation
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04713  Circadian entrainment
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04728  Dopaminergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05205  Proteoglycans in cancer
Disease
H00264  Charcot-Marie-Tooth disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04020 Calcium signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04070 Phosphatidylinositol signaling system
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04022 cGMP-PKG signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04210 Apoptosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04218 Cellular senescence
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04621 NOD-like receptor signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04625 C-type lectin receptor signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09152 Endocrine system
   04911 Insulin secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04922 Glucagon signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04929 GnRH secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04912 GnRH signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04915 Estrogen signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04921 Oxytocin signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04935 Growth hormone synthesis, secretion and action
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04918 Thyroid hormone synthesis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04928 Parathyroid hormone synthesis, secretion and action
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04924 Renin secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04925 Aldosterone synthesis and secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04927 Cortisol synthesis and secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09154 Digestive system
   04970 Salivary secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04971 Gastric acid secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04972 Pancreatic secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09156 Nervous system
   04724 Glutamatergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04725 Cholinergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04728 Dopaminergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04726 Serotonergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04720 Long-term potentiation
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04730 Long-term depression
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04723 Retrograde endocannabinoid signaling
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09157 Sensory system
   04742 Taste transduction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04750 Inflammatory mediator regulation of TRP channels
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05163 Human cytomegalovirus infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05012 Parkinson disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05014 Amyotrophic lateral sclerosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05017 Spinocerebellar ataxia
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05020 Prion disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05022 Pathways of neurodegeneration - multiple diseases
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3710(ITPR3)
PTR: 462618(ITPR3)
PPS: 100982024(ITPR3)
GGO: 101124725(ITPR3)
PON: 100434127(ITPR3)
NLE: 100585914(ITPR3)
HMH: 116459671(ITPR3)
MCC: 718040(ITPR3)
MCF: 102116003(ITPR3)
MTHB: 126952707
MNI: 105474470(ITPR3)
CSAB: 103221654(ITPR3)
CATY: 105593244(ITPR3)
PANU: 101001272(ITPR3)
TGE: 112622816(ITPR3)
MLEU: 105544182(ITPR3)
RRO: 104658948(ITPR3)
RBB: 108516255(ITPR3)
TFN: 117087057(ITPR3)
PTEH: 111543148(ITPR3)
CANG: 105514217(ITPR3)
CJC: 100390843
SBQ: 101048916(ITPR3)
CIMI: 108300031(ITPR3)
CSYR: 103269243(ITPR3)
MMUR: 105861402(ITPR3)
LCAT: 123632820(ITPR3)
PCOQ: 105821681(ITPR3)
OGA: 100942290(ITPR3)
MMU: 16440(Itpr3)
MCAL: 110312193(Itpr3)
MPAH: 110338229(Itpr3)
RNO: 25679(Itpr3)
MCOC: 116075536(Itpr3)
ANU: 117724336(Itpr3)
MUN: 110543748(Itpr3)
CGE: 100751775
MAUA: 101838704(Itpr3)
PROB: 127224232(Itpr3)
PLEU: 114706123(Itpr3)
MORG: 121435401(Itpr3)
MFOT: 126499493
AAMP: 119823109(Itpr3)
NGI: 103739696(Itpr3)
HGL: 101706978(Itpr3)
CPOC: 100729184(Itpr3)
CCAN: 109686691(Itpr3)
DORD: 105999871(Itpr3)
DSP: 122111510(Itpr3)
PLOP: 125352691(Itpr3)
NCAR: 124988553
OCU: 100008939
OPI: 101516441(ITPR3)
TUP: 102475587(ITPR3)
GVR: 103597698
CFA: 481746(ITPR3)
CLUD: 112641421(ITPR3)
VVP: 112913900(ITPR3)
VLG: 121479576(ITPR3)
NPO: 129512495(ITPR3)
AML: 100471747(ITPR3)
UMR: 103665553(ITPR3)
UAH: 113243814(ITPR3)
UAR: 123790908(ITPR3)
ELK: 111152507
LLV: 125103123
MPUF: 101688102(ITPR3)
MNP: 132017890(ITPR3)
NVS: 122910530(ITPR3)
ORO: 101380808(ITPR3)
EJU: 114222155(ITPR3)
ZCA: 113927035(ITPR3)
MLX: 118001326(ITPR3)
NSU: 110575641(ITPR3)
LWW: 102745629
FCA: 101087993(ITPR3)
PYU: 121029298(ITPR3)
PCOO: 112862849(ITPR3)
PBG: 122489417(ITPR3)
LRUF: 124528059
PTG: 102967639(ITPR3)
PPAD: 109271454(ITPR3)
PUC: 125938355
AJU: 106976077
HHV: 120238181(ITPR3)
BTA: 281879(ITPR3)
BOM: 102271039(ITPR3)
BIU: 109576552(ITPR3)
BBUB: 102409793(ITPR3)
BBIS: 104995001(ITPR3)
CHX: 102184768(ITPR3)
OAS: 114109674(ITPR3)
BTAX: 128056281(ITPR3)
ODA: 120869823(ITPR3)
CCAD: 122430147(ITPR3)
MBEZ: 129543844(ITPR3)
SSC: 100155015(ITPR3)
CFR: 102524078(ITPR3)
CBAI: 105064212(ITPR3)
CDK: 105101373(ITPR3)
VPC: 102527986(ITPR3)
BACU: 102999302(ITPR3)
LVE: 103070387(ITPR3)
OOR: 101280894(ITPR3)
DLE: 111178692(ITPR3)
PCAD: 102992034(ITPR3)
PSIU: 116761675(ITPR3)
NASI: 112414026(ITPR3)
ECB: 100053019(ITPR3)
EPZ: 103564724(ITPR3)
EAI: 106834634(ITPR3)
MYB: 102241889(ITPR3)
MYD: 102764661(ITPR3)
MMYO: 118679657(ITPR3)
MLF: 102442861(ITPR3)
MNA: 107541588(ITPR3)
PKL: 118705642(ITPR3)
EFUS: 103303043(ITPR3)
HAI: 109392407(ITPR3)
DRO: 112302101(ITPR3)
SHON: 118991502(ITPR3)
AJM: 119041225(ITPR3)
PDIC: 114493819(ITPR3)
PHAS: 123815944(ITPR3)
MMF: 118621173(ITPR3)
RFQ: 117020871(ITPR3)
PALE: 102881783(ITPR3)
PGIG: 120597599(ITPR3)
PVP: 105301042(ITPR3)
RAY: 107511965(ITPR3)
MJV: 108402938(ITPR3)
TOD: 119252349(ITPR3)
SARA: 101555935(ITPR3)
LAV: 100659666(ITPR3)
TMU: 101354392
ETF: 101657031(ITPR3)
DNM: 101425999(ITPR3)
MDO: 100025596(ITPR3)
GAS: 123246373(ITPR3)
SHR: 100916996(ITPR3)
AFZ: 127561144
PCW: 110217180(ITPR3)
OAA: 100088770(ITPR3)
GGA: 419910(ITPR3)
PCOC: 116236926(ITPR3)
MGP: 104914537(ITPR3)
CJO: 107324903(ITPR3)
TPAI: 128088141(ITPR3)
LMUT: 125684288(ITPR3)
NMEL: 110388144(ITPR3)
APLA: 101792202(ITPR3)
ACYG: 106046157(ITPR3)
CATA: 118259507(ITPR3)
AFUL: 116498720(ITPR3)
TGU: 100227554(ITPR3)
LSR: 110477170(ITPR3)
SCAN: 103823305(ITPR3)
PMOA: 120495874(ITPR3)
OTC: 121347941(ITPR3)
PRUF: 121353993(ITPR3)
GFR: 102036728(ITPR3)
FAB: 101809694(ITPR3)
OMA: 130263660(ITPR3)
PHI: 102109497(ITPR3)
PMAJ: 107214964(ITPR3)
CCAE: 111939798(ITPR3)
CCW: 104692535(ITPR3)
CBRC: 103625304(ITPR3)
ETL: 114064083(ITPR3)
ZAB: 102072204(ITPR3)
ACHL: 103804766
SVG: 106851022(ITPR3)
MMEA: 130585047(ITPR3)
HRT: 120762731(ITPR3)
FPG: 101911646(ITPR3)
FCH: 102057380(ITPR3)
CLV: 102098742(ITPR3)
EGZ: 104125774(ITPR3)
NNI: 104013165(ITPR3)
PCRI: 104027348(ITPR3)
PLET: 104628694
EHS: 104505934(ITPR3)
PCAO: 104053101
ACUN: 113488982(ITPR3)
TALA: 104366224(ITPR3)
PADL: 103919873(ITPR3)
AFOR: 103893713(ITPR3)
ACHC: 115334771(ITPR3)
HALD: 104313840(ITPR3)
HLE: 104842381(ITPR3)
AGEN: 126052517
GCL: 127026155
CCRI: 104167680(ITPR3)
CMAC: 104481510
MUI: 104537163(ITPR3)
BREG: 104634835(ITPR3)
FGA: 104076543(ITPR3)
GSTE: 104263844(ITPR3)
LDI: 104349817(ITPR3)
MNB: 103772908(ITPR3)
OHA: 104335704(ITPR3)
NNT: 104412975(ITPR3)
SHAB: 115602289(ITPR3)
DPUB: 104305385(ITPR3)
PGUU: 104467564(ITPR3)
ACAR: 104532633(ITPR3)
CPEA: 104397170(ITPR3)
AVIT: 104276386(ITPR3)
CVF: 104289376(ITPR3)
RTD: 128900196(ITPR3)
CUCA: 104067088(ITPR3)
TEO: 104378141(ITPR3)
BRHI: 104493057(ITPR3)
AAM: 106496749(ITPR3)
AROW: 112961456(ITPR3)
NPD: 112959174(ITPR3)
TGT: 104566631(ITPR3)
DNE: 112990188(ITPR3)
SCAM: 104142092(ITPR3)
ASN: 102381395(ITPR3)
AMJ: 102567087(ITPR3)
CPOO: 109317804(ITPR3)
GGN: 109295368(ITPR3)
PSS: 102449833(ITPR3)
CMY: 102939145(ITPR3)
CCAY: 125625000(ITPR3)
DCC: 119846303(ITPR3)
CPIC: 101935702(ITPR3)
TST: 117875864(ITPR3)
CABI: 116818020(ITPR3)
MRV: 120403535(ITPR3)
ACS: 100564450(itpr3)
PVT: 110080162(ITPR3)
SUND: 121928090(ITPR3)
PBI: 103048008(ITPR3)
PMUR: 107287061(ITPR3)
CTIG: 120299035(ITPR3)
TSR: 106541215(ITPR3)
PGUT: 117663981(ITPR3)
APRI: 131195056(ITPR3)
VKO: 123030371(ITPR3)
PMUA: 114599227(ITPR3)
PRAF: 128416015(ITPR3)
ZVI: 118089408(ITPR3)
HCG: 128323350(ITPR3)
GJA: 107117556(ITPR3)
STOW: 125433368(ITPR3)
EMC: 129330751(ITPR3)
XLA: 108709441
XTR: 100124749(itpr3)
NPR: 108787281(ITPR3)
RTEM: 120928318(ITPR3)
BBUF: 120995158(ITPR3)
BGAR: 122933262(ITPR3)
MUO: 115481356(ITPR3)
GSH: 117347078(ITPR3)
DRE: 794666(itpr3)
SANH: 107668074(itpr3) 107695219
SGH: 107549213(itpr3) 107555587
CCAR: 109061957
PTET: 122349960
LROH: 127169168(itpr3)
OMC: 131546325(itpr3)
PPRM: 120485173
MAMB: 125279368(itpr3)
CIDE: 127517038
TROS: 130567607(itpr3)
MANU: 129414027(itpr3)
IPU: 108265736
IFU: 128607949(itpr3)
PHYP: 113526579(itpr3)
SMEO: 124399884(itpr3)
TFD: 113655915(itpr3)
CMAO: 118813746(itpr3)
EEE: 113581076(itpr3)
CHAR: 105894296(itpr3)
TRU: 101074918
TFS: 130530401(itpr3)
LCO: 104933529(itpr3)
CGOB: 115010526(itpr3)
ELY: 117257969(itpr3)
EFO: 125892424(itpr3)
SLUC: 116063113(itpr3)
PFLV: 114558603
GAT: 120829151(itpr3)
PPUG: 119222835(itpr3)
AFB: 129100010
CLUM: 117733021(itpr3)
MSAM: 119905085(itpr3)
CUD: 121517298(itpr3)
ALAT: 119022453(itpr3)
MZE: 101481255(itpr3)
ONL: 100707448(itpr3)
OAU: 116310193(itpr3)
OLA: 101170574(itpr3)
OML: 112158759(itpr3)
XMA: 102237995(itpr3)
XCO: 114141097(itpr3)
PRET: 103468120(itpr3)
PFOR: 103156233(itpr3)
PLAI: 106955508(itpr3)
PMEI: 106933653(itpr3)
GAF: 122838832(itpr3)
CVG: 107097408(itpr3)
CTUL: 119777951(itpr3)
GMU: 124872108(itpr3)
NFU: 107391515(itpr3)
KMR: 108251566(itpr3)
ALIM: 106527884
NWH: 119417370(itpr3)
MCEP: 125008315(itpr3)
CSEM: 103384462(itpr3)
POV: 109642872
SSEN: 122777265(itpr3)
HHIP: 117764635(itpr3)
HSP: 118111281(itpr3)
LCF: 108879748(itpr3)
SDU: 111235419(itpr3)
SLAL: 111673377(itpr3)
XGL: 120803636(itpr3)
HCQ: 109526465(itpr3)
SSCV: 125988671
BPEC: 110158040(itpr3)
MALB: 109970976(itpr3)
BSPL: 114858253(itpr3)
ONE: 115117655 115132159(itpr3)
SALP: 111966445(itpr3) 111976834
ELS: 105027760(itpr3)
SFM: 108931222(itpr3)
PKI: 111844730(itpr3)
AANG: 118208164(itpr3)
LOC: 102696500(itpr3)
PSEX: 120526198(itpr3)
LCM: 102349825(ITPR3)
CMK: 103179112(itpr3)
CPLA: 122563221(itpr3)
LERI: 129708665(itpr3)
LPOL: 106460236
SMIN: v1.2.035044.t1(symbB.v1.2.035044.t1)
EHX: EMIHUDRAFT_209909(IPR1)
 » show all
Reference
  Authors
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
  Title
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
  Journal
J Biol Chem 280:10305-17 (2005)
DOI:10.1074/jbc.M413824200
  Sequence
[mmu:16440]
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