KEGG   ORTHOLOGY: K05068
Entry
K05068                      KO                                     

Symbol
IL2RA, CD25
Name
interleukin 2 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
Disease
H00091  T-B+Severe combined immunodeficiency
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04151 PI3K-Akt signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04658 Th1 and Th2 cell differentiation
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04659 Th17 cell differentiation
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   05162 Measles
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04090 CD molecules
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05068  IL2RA, CD25; interleukin 2 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05068  CD25, IL2RA; interleukin 2 receptor, alpha
Other DBs
GO: 0004911
Genes
HSA: 3559(IL2RA)
PTR: 450884(IL2RA)
PPS: 100974407(IL2RA)
GGO: 101126210(IL2RA)
PON: 100440118(IL2RA)
NLE: 100582107(IL2RA)
MCC: 574300(IL2RA)
MCF: 102123605(IL2RA)
CSAB: 103237839(IL2RA)
CATY: 105597428(IL2RA)
PANU: 101004576(IL2RA)
RRO: 104664846(IL2RA)
RBB: 108529907(IL2RA)
TFN: 117082099(IL2RA)
PTEH: 111554868(IL2RA)
CJC: 100412016(IL2RA)
SBQ: 101036589(IL2RA)
MMUR: 105858205(IL2RA)
MMU: 16184(Il2ra)
MCAL: 110289347(Il2ra)
MPAH: 110334116(Il2ra)
RNO: 25704(Il2ra)
MCOC: 116082367(Il2ra)
MUN: 110556899(Il2ra)
CGE: 100764797(Il2ra)
PLEU: 114708790(Il2ra)
NGI: 103727306(Il2ra)
HGL: 101696651(Il2ra)
CCAN: 109690611(Il2ra)
TUP: 102503225(IL2RA)
CFA: 403870(IL2RA)
VVP: 112933655(IL2RA)
VLG: 121496900(IL2RA)
AML: 100466247(IL2RA)
UMR: 103676245(IL2RA)
UAH: 113241140(IL2RA)
ORO: 101378506(IL2RA)
ELK: 111158621
MPUF: 101683684(IL2RA)
EJU: 114217727(IL2RA)
MLX: 118021614(IL2RA)
FCA: 493953(IL2RA)
PYU: 121014860(IL2RA)
PPAD: 109273771(IL2RA)
AJU: 106982335(IL2RA)
HHV: 120237209(IL2RA)
BTA: 281861(IL2RA)
BOM: 102274858(IL2RA)
BIU: 109567961(IL2RA)
BBUB: 102405003(IL2RA)
CHX: 102170059(IL2RA)
OAS: 443435(IL2RA)
ODA: 120869146(IL2RA)
CCAD: 122448159(IL2RA)
SSC: 396814(IL2RA)
CFR: 102520401(IL2RA)
CBAI: 105074697(IL2RA)
CDK: 105091372(IL2RA)
BACU: 102999308(IL2RA)
LVE: 103090256(IL2RA)
OOR: 101275717(IL2RA)
DLE: 111177977(IL2RA)
PCAD: 102974550(IL2RA)
ECB: 100070292(IL2RA)
EPZ: 103548896(IL2RA)
EAI: 106833795(IL2RA)
MYB: 102249529(IL2RA)
MYD: 102769642(IL2RA)
MMYO: 118672311(IL2RA)
MNA: 107542420(IL2RA)
HAI: 109383783(IL2RA)
DRO: 112321040(IL2RA)
SHON: 119000807(IL2RA)
AJM: 119048017(IL2RA)
MMF: 118632297(IL2RA)
PALE: 102891511(IL2RA)
PGIG: 120609005(IL2RA)
RAY: 107505982(IL2RA)
MJV: 108384839(IL2RA)
TOD: 119244171(IL2RA)
LAV: 100655361(IL2RA)
TMU: 101342095
MDO: 103093188(IL2RA)
SHR: 105750698(IL2RA)
PCW: 110198993(IL2RA)
OAA: 103165385(IL2RA)
GGA: 395294(IL2RA)
PCOC: 116239606
MGP: 100547769
CJO: 107315066
NMEL: 110392238(IL15RA)
APLA: 101789606
ACYG: 106038749(IL2RA)
TGU: 100222957
LSR: 110470954
SCAN: 103822517
PMOA: 120512514
FAB: 101805774
PHI: 102109566
PMAJ: 107204108
CCAE: 111923146
CCW: 104694531
ETL: 114067844(IL15RA)
FPG: 101919123
FCH: 102049741
CLV: 102090507
EGZ: 104134819
NNI: 104010490
ACUN: 113475946(IL15RA)
PADL: 103920842
AAM: 106487990
NPD: 112958573
ASN: 102369874
AMJ: 106737583(IL2RA)
CPOO: 109315828
GGN: 109292241
PSS: 102451419
CMY: 102937403(IL2RA)
CPIC: 101934224(IL2RA)
TST: 117867397(IL2RA)
CABI: 116823520(IL2RA)
ACS: 103278808(il2ra)
PVT: 110088980
PMUR: 107294425(IL15RA)
PMUA: 114604914(IL2RA)
GJA: 107120141
LCM: 106704263
 » show all
Reference
PMID:6090949
  Authors
Nikaido T, Shimizu A, Ishida N, Sabe H, Teshigawara K, Maeda M, Uchiyama T, Yodoi J, Honjo T
  Title
Molecular cloning of cDNA encoding human interleukin-2 receptor.
  Journal
Nature 311:631-5 (1984)
DOI:10.1038/311631a0
  Sequence
[hsa:3559]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Knevel R, de Rooy DP, Zhernakova A, Grondal G, Krabben A, Steinsson K, Wijmenga C, Cavet G, Toes RE, Huizinga TW, Gregersen PK, van der Helm-van Mil AH
  Title
Association of variants in IL2RA with progression of joint destruction in rheumatoid arthritis.
  Journal
Arthritis Rheum 65:1684-93 (2013)
DOI:10.1002/art.37938
  Sequence
[hsa:3559]
LinkDB

KEGG   ORTHOLOGY: K05069
Entry
K05069                      KO                                     

Symbol
IL2RB, CD122
Name
interleukin 2 receptor beta
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04151 PI3K-Akt signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04659 Th17 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05202 Transcriptional misregulation in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05162 Measles
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04090 CD molecules
    K05069  IL2RB, CD122; interleukin 2 receptor beta
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05069  IL2RB, CD122; interleukin 2 receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05069  CD122, IL2RB; interleukin 2 receptor, beta
Other DBs
GO: 0004911
Genes
HSA: 3560(IL2RB)
PTR: 470203(IL2RB)
PPS: 100992438(IL2RB)
GGO: 101139583(IL2RB)
PON: 100460977(IL2RB)
NLE: 100581366(IL2RB)
MCC: 696331(IL2RB)
MCF: 102138714(IL2RB)
CSAB: 103223268(IL2RB)
CATY: 105575817(IL2RB)
PANU: 101014683(IL2RB)
RRO: 104682498(IL2RB)
RBB: 108512733(IL2RB)
TFN: 117070006(IL2RB)
PTEH: 111549045(IL2RB)
CJC: 100394910(IL2RB)
SBQ: 101030332(IL2RB)
MMUR: 105883739(IL2RB)
MMU: 16185(Il2rb)
MCAL: 110310694(Il2rb)
MPAH: 110335025(Il2rb)
RNO: 25746(Il2rb)
MCOC: 116075473(Il2rb)
MUN: 110548465(Il2rb)
CGE: 113832088
PLEU: 114694353(Il2rb)
NGI: 103748643(Il2rb)
HGL: 101726369(Il2rb)
CCAN: 109698250(Il2rb)
TUP: 102467660(IL2RB)
CFA: 403439(IL2RB)
VVP: 112929101(IL2RB)
VLG: 121490488(IL2RB)
AML: 100478292(IL2RB)
UMR: 103676409(IL2RB)
ORO: 101366322(IL2RB)
ELK: 111157559
MPUF: 101674646(IL2RB)
EJU: 114218365(IL2RB)
MLX: 117998718(IL2RB)
FCA: 101092622(IL2RB)
PTG: 102965369(IL2RB)
PPAD: 109265527(IL2RB)
AJU: 106981084(IL2RB)
HHV: 120241202(IL2RB)
BTA: 104968644(IL2RB) 510185
BOM: 102284639(IL2RB) 106700824
BIU: 109559534(IL2RB)
BBUB: 102391873 102392192(IL2RB)
OAS: 101107088(IL2RB)
CCAD: 122423665(IL2RB) 122423666
SSC: 100621776(IL2RB)
CFR: 102524470(IL2RB)
CBAI: 105073156(IL2RB)
CDK: 105101578(IL2RB)
BACU: 103006990(IL2RB)
LVE: 103071005(IL2RB)
OOR: 101271954(IL2RB)
DLE: 111186349(IL2RB)
PCAD: 102995923(IL2RB)
ECB: 100069676(IL2RB)
EPZ: 103564462(IL2RB)
EAI: 106837581(IL2RB)
MYB: 102241115(IL2RB)
MYD: 102768408(IL2RB)
MMYO: 118651872(IL2RB)
MNA: 107545294(IL2RB)
HAI: 109394467(IL2RB)
DRO: 112321925(IL2RB)
SHON: 119002352(IL2RB)
AJM: 119060429(IL2RB)
MMF: 118624074(IL2RB)
PALE: 102883396(IL2RB)
PGIG: 120614851(IL2RB)
RAY: 107519288(IL2RB)
MJV: 108392662(IL2RB)
TOD: 119247294(IL2RB)
LAV: 100669139(IL2RB)
TMU: 101344371
MDO: 100025393(IL2RB)
SHR: 100913275(IL2RB)
PCW: 110205742(IL2RB)
OAA: 100092851(IL2RB)
GGA: 100859707(IL2RB)
PCOC: 116233307(IL2RB)
MGP: 104911125(IL2RB)
CJO: 107313789(IL2RB)
NMEL: 110393218(IL2RB)
APLA: 101791719(IL2RB)
ACYG: 106035899(IL2RB)
TGU: 101232975(IL2RB)
LSR: 110483875(IL2RB)
SCAN: 103813230(IL2RB)
PMOA: 120510114(IL2RB)
GFR: 102031500(IL2RB)
FAB: 101809303(IL2RB)
PHI: 102106386(IL2RB)
PMAJ: 107204849(IL2RB)
CCAE: 111935345(IL2RB)
CCW: 104696293(IL2RB)
ETL: 114055414(IL2RB)
FPG: 101915263(IL2RB)
FCH: 102058748(IL2RB)
CLV: 102091469(IL2RB)
EGZ: 104134213(IL2RB)
NNI: 104021675(IL2RB)
ACUN: 113475953(IL2RB)
PADL: 103924145(IL2RB)
AAM: 106488409(IL2RB)
NPD: 112947763(IL2RB)
ASN: 102376875(IL2RB)
AMJ: 102571730(IL2RB)
CPOO: 109316634(IL2RB)
GGN: 109296052(IL2RB)
PSS: 102449512(IL2RB)
CMY: 102936500(IL2RB)
CPIC: 101932173(IL2RB)
TST: 117880784(IL2RB)
CABI: 116824117(IL2RB)
ACS: 103278848(il2rb)
PVT: 110075925(IL2RB)
PBI: 112541087(IL2RB)
PMUR: 107302587(IL2RB)
TSR: 106555941(IL2RB)
PGUT: 117655570(IL2RB)
PMUA: 114605576(IL2RB)
ZVI: 118090827(IL2RB)
GJA: 107120056(IL2RB)
XTR: 101731938(il2rb)
DRE: 793920(il2rb)
IPU: 108272990 108273212(il2rb)
TRU: 101076872
LCO: 104936154(il2rb)
NCC: 104964346
ELY: 117254604 117268216(il2rb)
PLEP: 121941886 121957046(il2rb)
SLUC: 116042721 116065251(il2rb)
ECRA: 117952358 117957756(il2rb)
PFLV: 114563754(csf2rb) 114563768 114570378(il2rb)
GAT: 120828204(il2rb)
MSAM: 119885295(il2rb) 119898625
OLA: 101165891 105354598(csf2rb)
OML: 112137100 112146641(il2rb)
PRET: 103468486
ALIM: 106520638 106522494(csf2rb)
AOCE: 111579444 111579883(csf2rb)
LCF: 108877635(il2rb)
XGL: 120785060(il2rb) 120800036
HCQ: 109520288
MALB: 109972408(il2rb)
ELS: 105009012(il2rb) 105029657
LOC: 102688112(il2rb)
PSPA: 121309365(il2rb)
LCM: 102367350
CMK: 103189779(il2rb)
RTP: 109914787(il2rb)
 » show all
Reference
PMID:2785715
  Authors
Hatakeyama M, Tsudo M, Minamoto S, Kono T, Doi T, Miyata T, Miyasaka M, Taniguchi T
  Title
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
  Journal
Science 244:551-6 (1989)
DOI:10.1126/science.2785715
  Sequence
[hsa:3560]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ
  Title
Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis.
  Journal
Genes Immun 8:79-83 (2007)
DOI:10.1038/sj.gene.6364355
  Sequence
[hsa:3560]
LinkDB

KEGG   ORTHOLOGY: K05070
Entry
K05070                      KO                                     

Symbol
IL2RG, CD132
Name
interleukin 2 receptor gamma
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04144  Endocytosis
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
map05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
H00093  Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04151 PI3K-Akt signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04659 Th17 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05162 Measles
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05340 Primary immunodeficiency
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04090 CD molecules
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05070  IL2RG, CD132; interleukin 2 receptor gamma
CD molecules [BR:ko04090]
 Proteins
  K05070  CD132, IL2RG; interleukin 2 receptor, gamma (severe combined immunodeficiency)
Other DBs
GO: 0004911
Genes
HSA: 3561(IL2RG)
PTR: 101059843(IL2RG)
PPS: 100986679(IL2RG)
PON: 100454903(IL2RG)
NLE: 100585758(IL2RG)
MCC: 641338(IL2RG)
MCF: 102144912(IL2RG)
CSAB: 103232148(IL2RG)
CATY: 105586122(IL2RG)
PANU: 101008968(IL2RG)
RRO: 104656782(IL2RG)
RBB: 108532108(IL2RG)
TFN: 117077624(IL2RG)
PTEH: 111533635(IL2RG)
CJC: 100388189(IL2RG)
SBQ: 101047979(IL2RG)
MMUR: 105855320(IL2RG)
MMU: 16186(Il2rg)
MCAL: 110286942(Il2rg)
MPAH: 110313918(Il2rg)
RNO: 140924(Il2rg)
MCOC: 116087170(Il2rg)
MUN: 110564656(Il2rg)
CGE: 100756284(Il2rg)
PLEU: 114708654(Il2rg)
NGI: 103751955(Il2rg)
HGL: 101715243(Il2rg)
CCAN: 109673990(Il2rg)
OCU: 103351862(IL2RG)
TUP: 102476004(IL2RG)
CFA: 403851(IL2RG)
VVP: 112907637(IL2RG)
VLG: 121483086(IL2RG)
AML: 100468126(IL2RG)
UMR: 103682591(IL2RG)
UAH: 113245610(IL2RG)
ORO: 101374379(IL2RG)
ELK: 111161041
MPUF: 101678968(IL2RG)
MLX: 118025926(IL2RG)
FCA: 101090239(IL2RG)
PYU: 121025256(IL2RG)
PTG: 102966580(IL2RG)
PPAD: 109254610(IL2RG)
AJU: 106982399(IL2RG)
HHV: 120246070(IL2RG)
BTA: 281862(IL2RG)
BOM: 102266681(IL2RG)
BIU: 109555190(IL2RG)
BBUB: 102402566(IL2RG)
CHX: 102169656(IL2RG)
OAS: 101103538(IL2RG)
ODA: 120882006(IL2RG)
CCAD: 122434652(IL2RG)
SSC: 397156(IL2RG)
CBAI: 105083690(IL2RG)
CDK: 105087982(IL2RG)
BACU: 103016442(IL2RG)
LVE: 103087530(IL2RG)
OOR: 101286718(IL2RG)
DLE: 111167807(IL2RG)
PCAD: 102979617(IL2RG)
ECB: 100055911(IL2RG)
EPZ: 103544610(IL2RG)
EAI: 106828880(IL2RG)
MYB: 102241164(IL2RG)
MYD: 102757155(IL2RG)
MMYO: 118654549(IL2RG) 118661694(METTL8)
MNA: 107532895(IL2RG)
HAI: 109385585(IL2RG)
DRO: 112300079(IL2RG)
AJM: 119035395(IL2RG)
MMF: 118635917(IL2RG)
PALE: 102888070(IL2RG)
PGIG: 120585387(IL2RG)
RAY: 107513773(IL2RG)
MJV: 108403309(IL2RG)
TOD: 119246676(IL2RG)
LAV: 100664834(IL2RG)
TMU: 101359472
MDO: 100619507(IL2RG)
SHR: 100929781(IL2RG)
PCW: 110201024(IL2RG)
OAA: 114812802(IL2RG)
GGA: 395199(IL2RG)
PCOC: 116229598(IL2RG)
MGP: 104912104(IL2RG)
CJO: 107312576(IL2RG)
NMEL: 110403135(IL2RG)
APLA: 101794194(IL2RG)
ACYG: 106037383(IL2RG)
TGU: 100226174(IL2RG)
LSR: 110472683(IL2RG)
SCAN: 103824248(IL2RG)
PMOA: 120506133(IL2RG)
GFR: 102043888(IL2RG)
FAB: 107603321(IL2RG)
PHI: 102112500(IL2RG)
PMAJ: 107203656(IL2RG)
CCAE: 111929372(IL2RG)
CCW: 104691748(IL2RG)
ETL: 114067449(IL2RG)
FPG: 101923008(IL2RG)
FCH: 102052025(IL2RG)
CLV: 102094834(IL2RG)
EGZ: 104124289(IL2RG)
NNI: 104012899(IL2RG)
ACUN: 113479902(IL2RG)
PADL: 103923348(IL2RG)
NPD: 112948661(IL2RG)
ASN: 102379602(IL2RG)
AMJ: 102575498(IL2RG)
GGN: 109300562(IL2RG)
PSS: 102443813(IL2RG)
CMY: 102933244(IL2RG)
CPIC: 101931356(IL2RG)
TST: 117883178(IL2RG)
CABI: 116833382(IL2RG)
ACS: 103281066(il2rg)
PVT: 110080214(IL2RG)
PBI: 103061889(IL2RG)
PMUR: 107303211(IL2RG)
PGUT: 117679627(IL2RG)
PMUA: 114589433(IL2RG)
ZVI: 118078798(IL2RG)
GJA: 107108490(IL2RG)
XLA: 100036958(il2rg.L)
XTR: 100492995(il2rg)
NPR: 108800627(IL2RG)
DRE: 100144554(il2rgb) 796604(il2rga)
IPU: 108269358(il2rg) 108276805
TRU: 100190946(il2rg)
LCO: 104938889
NCC: 104967331
CGOB: 115018623
SLUC: 116037024
ECRA: 117956151
GAT: 120821796
MSAM: 119894956
CUD: 121518414
OLA: 101156347
OML: 112138762
XMA: 102230559
XCO: 114152754
XHE: 116728980
PRET: 103475386
CVG: 107084171
NFU: 107386732
AOCE: 111573091
CSEM: 103395485(il2rg)
POV: 109635689
SDU: 111217233(il2rg)
SLAL: 111672069
XGL: 120802360
HCQ: 109512452
MALB: 109960011
OMY: 100136033 101268908(il2rc2)
SALP: 111964368
LCM: 102356230(IL2RG)
 » show all
Reference
PMID:1631559
  Authors
Takeshita T, Asao H, Ohtani K, Ishii N, Kumaki S, Tanaka N, Munakata H, Nakamura M, Sugamura K
  Title
Cloning of the gamma chain of the human IL-2 receptor.
  Journal
Science 257:379-82 (1992)
DOI:10.1126/science.1631559
  Sequence
[hsa:3561]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Zhang Q, Wang HY, Liu X, Bhutani G, Kantekure K, Wasik M
  Title
IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.
  Journal
Proc Natl Acad Sci U S A 108:11977-82 (2011)
DOI:10.1073/pnas.1100319108
  Sequence
[hsa:3561]
LinkDB

KEGG   ORTHOLOGY: K04737
Entry
K04737                      KO                                     

Symbol
IL3RA, CD123
Name
interleukin 3 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
   04151 PI3K-Akt signaling pathway
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
   04090 CD molecules
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K04737  IL3RA, CD123; interleukin 3 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K04737  CD123, IL3RA; interleukin 3 receptor, alpha (low affinity)
Other DBs
GO: 0004912
Genes
HSA: 3563(IL3RA)
PPS: 100967540(IL3RA)
PON: 100462256
MCC: 106995138(IL3RA) 114675718
MCF: 102138639
CSAB: 103247515(IL3RA)
CATY: 105574782(IL3RA)
PANU: 101000289
RRO: 104663347(IL3RA)
RBB: 108520941(IL3RA)
TFN: 117076154(IL3RA)
PTEH: 111535429
CJC: 100405472(IL3RA)
SBQ: 101039092(IL3RA)
MMUR: 105870810(IL3RA)
MMU: 16188(Il3ra)
MCAL: 110309476
MPAH: 110325021
RNO: 246144(Il3ra)
MCOC: 116078335
MUN: 110543786
CGE: 113838537
NGI: 103750125(Il3ra)
HGL: 101696721(Il3ra)
CCAN: 109688754(Il3ra)
OCU: 103345135(IL3RA)
TUP: 102476020(IL3RA)
CFA: 609293(IL3RA)
VVP: 112908954(IL3RA)
VLG: 121482408(IL3RA)
AML: 105238362(IL3RA)
UMR: 103666330(IL3RA)
UAH: 113240790(IL3RA)
ORO: 101383763(IL3RA)
ELK: 111157156
MPUF: 101671295(IL3RA)
EJU: 114218041(IL3RA)
MLX: 118026667(IL3RA)
FCA: 105261394(IL3RA)
PPAD: 109256147(IL3RA)
AJU: 113597168(IL3RA)
HHV: 120240554(IL3RA)
BTA: 100299249(IL3RA)
BOM: 102279846
BBUB: 102399807(IL3RA)
CHX: 102178527(IL3RA)
OAS: 101113991(IL3RA)
ODA: 120882424(IL3RA)
CCAD: 122434356(IL3RA)
CFR: 102512136(IL3RA)
CBAI: 105079513(IL3RA)
CDK: 105103091(IL3RA)
BACU: 103005335(IL3RA)
LVE: 103083417(IL3RA)
OOR: 105748918(IL3RA)
DLE: 111168262(IL3RA)
PCAD: 102987302(IL3RA)
ECB: 106781070
MYD: 102758217
MMYO: 118657316(IL3RA)
MNA: 107543962(IL3RA)
HAI: 109375560(IL3RA)
DRO: 112313317(IL3RA)
SHON: 118974342(IL3RA)
AJM: 119045748(IL3RA)
MMF: 118636573(IL3RA)
PALE: 102878242(IL3RA)
PGIG: 120589517(IL3RA)
RAY: 107512530(IL3RA)
MJV: 108389002(IL3RA)
LAV: 104847204(IL3RA)
TMU: 101359308
MDO: 103094311(IL3RA)
SHR: 100917948(IL3RA) 105749995
PCW: 110212842(IL3RA)
 » show all
Reference
PMID:1833064
  Authors
Kitamura T, Sato N, Arai K, Miyajima A
  Title
Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors.
  Journal
Cell 66:1165-74 (1991)
DOI:10.1016/0092-8674(91)90039-2
  Sequence
[hsa:3563]
Reference
  Authors
Geijsen N, Koenderman L, Coffer PJ
  Title
Specificity in cytokine signal transduction: lessons learned from the IL-3/IL-5/GM-CSF receptor family.
  Journal
Cytokine Growth Factor Rev 12:19-25 (2001)
DOI:10.1016/S1359-6101(00)00019-8
Reference
PMID:8948019
  Authors
Hara T, Miyajima A
  Title
Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis.
  Journal
Stem Cells 14:605-18 (1996)
DOI:10.1002/stem.140605
  Sequence
[hsa:3563]
LinkDB

KEGG   ORTHOLOGY: K05071
Entry
K05071                      KO                                     

Symbol
IL4R, CD124
Name
interleukin 4 receptor
Pathway
map04060  Cytokine-cytokine receptor interaction
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H00079  Asthma
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
   04151 PI3K-Akt signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05071  IL4R, CD124; interleukin 4 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05071  IL4R, CD124; interleukin 4 receptor
   04658 Th1 and Th2 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
   04659 Th17 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05071  IL4R, CD124; interleukin 4 receptor
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05071  IL4R, CD124; interleukin 4 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05071  IL4R, CD124; interleukin 4 receptor
   04090 CD molecules
    K05071  IL4R, CD124; interleukin 4 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05071  IL4R, CD124; interleukin 4 receptor
CD molecules [BR:ko04090]
 Proteins
  K05071  CD124, IL4R; interleukin 4 receptor
Other DBs
GO: 0004913
Genes
HSA: 3566(IL4R)
PTR: 454005(IL4R)
PPS: 100969808(IL4R)
GGO: 101124934(IL4R)
PON: 100449812(IL4R)
NLE: 100606206(IL4R)
MCC: 705404(IL4R)
MCF: 102133649(IL4R)
CSAB: 103230069(IL4R)
CATY: 105598447(IL4R)
PANU: 101022672(IL4R)
RRO: 104665638(IL4R)
RBB: 108538856(IL4R)
TFN: 117087558(IL4R)
PTEH: 111526911(IL4R)
CJC: 100412639(IL4R)
SBQ: 101044733(IL4R)
MMUR: 105879693(IL4R)
MMU: 16190(Il4ra)
MCAL: 110299093(Il4r)
MPAH: 110322992(Il4r)
RNO: 25084(Il4r)
MCOC: 116102932(Il4r)
MUN: 110564641(Il4r)
CGE: 100762840(Il4r)
PLEU: 114692223(Il4r)
NGI: 103741011(Il4r)
HGL: 101704138(Il4r)
CCAN: 109698033(Il4r)
OCU: 100337721(IL4R)
TUP: 102469844(IL4R)
CFA: 489957(IL4R)
VVP: 112929179(IL4R)
VLG: 121487679(IL4R)
AML: 100476095(IL4R)
UMR: 103657902(IL4R)
UAH: 113267608(IL4R)
ORO: 101373228(IL4R)
ELK: 111162191
MPUF: 101671915(IL4R)
EJU: 114214562(IL4R)
MLX: 117999673(IL4R)
FCA: 101096277(IL4R)
PYU: 121022503(IL4R)
PTG: 102949893(IL4R)
PPAD: 109256524(IL4R)
AJU: 106966182(IL4R)
HHV: 120249049(IL4R)
BTA: 404154(IL4R)
BOM: 102273764(IL4R)
BIU: 109578521(IL4R)
BBUB: 102394204(IL4R)
CHX: 102176382(IL4R)
OAS: 101109063(IL4R)
ODA: 120876403(IL4R)
CCAD: 122432797(IL4R)
SSC: 397614(IL4R)
CFR: 102504937(IL4R)
CBAI: 105073657(IL4R)
CDK: 105098257(IL4R)
BACU: 103017383(IL4R)
LVE: 103085500(IL4R)
OOR: 101281237(IL4R)
DLE: 111182213(IL4R)
PCAD: 102979109(IL4R)
ECB: 791252(IL4R)
EPZ: 103556347(IL4R)
EAI: 106829083(IL4R)
MYB: 102243995
MYD: 102752440(IL4R)
HAI: 109385965(IL4R)
DRO: 112304724 112304842(IL4R)
SHON: 119001758(IL4R)
PALE: 102882815(IL4R)
PGIG: 120620155
RAY: 107506151(IL4R)
MJV: 108405149(IL4R)
TOD: 119241806(IL4R)
LAV: 100654822(IL4R)
TMU: 101351007
MDO: 103092514(IL4R)
SHR: 100922104(IL4R)
PCW: 110221658(IL4R)
OAA: 103164911(IL4R)
GGA: 416585(IL4R)
PCOC: 116237644(IL4R)
MGP: 100541265(IL4R)
CJO: 107320714(IL4R)
NMEL: 110405596(IL4R)
APLA: 101796552(IL4R)
ACYG: 106046042(IL4R)
TGU: 100220266(IL4R)
LSR: 110477758(IL4R)
SCAN: 103817792(IL4R)
PMOA: 120513203(IL4R)
GFR: 102032458(IL4R)
FAB: 101812385(IL4R)
PHI: 102114232(IL4R)
PMAJ: 107211179(IL4R)
CCAE: 111936216(IL4R)
CCW: 104684903(IL4R)
ETL: 114061435(IL4R)
FPG: 101913747(IL4R)
FCH: 102059925(IL4R)
CLV: 102092650(IL4R)
EGZ: 104131347(IL4R)
NNI: 104015288(IL4R)
ACUN: 113485935(IL4R)
PADL: 103913920(IL4R)
AAM: 106486134(IL4R)
NPD: 112959972(IL4R)
ASN: 102384900
AMJ: 102563749(IL4R)
CPOO: 109314783(IL4R)
GGN: 109294441(IL4R)
PSS: 102459395(IL4R)
CMY: 102929479(IL4R)
CPIC: 101942260(IL4R)
TST: 117883843(IL4R)
CABI: 116830029(IL4R)
ACS: 103281083(il4r)
PVT: 110085007
PBI: 103065038(IL4R)
TSR: 106546610(IL4R)
PGUT: 117667340(IL4R)
PMUA: 114584165(IL4R)
XTR: 101732450(il4r) 105948365
DRE: 563674(il4r.2)
SRX: 107745579
IPU: 108257347(il4r) 108280483
PHYP: 113535949(il4r) 113546473
AMEX: 111195543
EEE: 113575903(il4r)
CGOB: 115006399
SLUC: 116060507
ECRA: 117949713
MSAM: 119890718
MZE: 101486355
ONL: 100705710
OML: 112161274
XMA: 111608325
XHE: 116718939
CVG: 107086945
AOCE: 111587969
CSEM: 103398546
POV: 109624836
LCF: 108877014
SDU: 111219228
XGL: 120788110
BPEC: 110175441
SASA: 100195064(il4ra) 106601108
SALP: 111979922
SFM: 108932964
PKI: 111846440(il4r)
LOC: 107078986
LCM: 102349939
CMK: 103186635(il4r)
 » show all
Reference
PMID:2307934
  Authors
Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.
  Title
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
  Journal
J Exp Med 171:861-73 (1990)
DOI:10.1084/jem.171.3.861
  Sequence
[hsa:3566]
Reference
PMID:8124718
  Authors
Keegan AD, Nelms K, White M, Wang LM, Pierce JH, Paul WE
  Title
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.
  Journal
Cell 76:811-20 (1994)
DOI:10.1016/0092-8674(94)90356-5
LinkDB

KEGG   ORTHOLOGY: K05067
Entry
K05067                      KO                                     

Symbol
IL5RA. CD125
Name
interleukin 5 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
   04090 CD molecules
    K05067  IL5RA. CD125; interleukin 5 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K05067  IL5RA. CD125; interleukin 5 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05067  CD125, IL5RA; interleukin 5 receptor, alpha
Other DBs
GO: 0004914
Genes
HSA: 3568(IL5RA)
PTR: 737582(IL5RA)
PPS: 100988791(IL5RA)
GGO: 101146234(IL5RA)
PON: 100450437(IL5RA)
NLE: 100584044(IL5RA)
MCC: 704649(IL5RA)
MCF: 102115323(IL5RA)
CSAB: 103227929(IL5RA)
CATY: 105585716(IL5RA)
PANU: 101024506(IL5RA)
RRO: 104657349(IL5RA)
RBB: 108535573(IL5RA)
TFN: 117083166(IL5RA)
PTEH: 111546978(IL5RA)
CJC: 100414222(IL5RA)
SBQ: 101032072(IL5RA)
MMUR: 105867616(IL5RA)
MMU: 16192(Il5ra)
MCAL: 110296992(Il5ra)
MPAH: 110317305(Il5ra)
RNO: 114103(Il5ra)
MCOC: 116099354(Il5ra)
MUN: 110555889(Il5ra)
CGE: 100762117(Il5ra)
PLEU: 114705041(Il5ra)
NGI: 103751211(Il5ra)
HGL: 101701153(Il5ra)
CCAN: 109680312(Il5ra)
OCU: 100347606(IL5RA)
TUP: 102470335(IL5RA)
CFA: 476553(IL5RA)
VVP: 112913306(IL5RA)
VLG: 121495137(IL5RA)
AML: 100478972(IL5RA)
UMR: 103674266(IL5RA)
UAH: 113257099(IL5RA)
ORO: 101373063(IL5RA)
ELK: 111144290
MPUF: 101674740(IL5RA)
EJU: 114207772(IL5RA)
MLX: 118005390(IL5RA)
FCA: 101099031(IL5RA)
PYU: 121041339(IL5RA)
PTG: 102972625(IL5RA)
PPAD: 109254643(IL5RA)
AJU: 106969534(IL5RA)
HHV: 120237117(IL5RA)
BTA: 615848(IL5RA)
BOM: 102273605(IL5RA)
BIU: 109575848(IL5RA)
BBUB: 102407739(IL5RA)
CHX: 102190466(IL5RA)
OAS: 101111837(IL5RA)
ODA: 120867647(IL5RA)
CCAD: 122424893(IL5RA)
SSC: 100137085(IL5RA)
CFR: 102509405(IL5RA)
CBAI: 105074767(IL5RA)
CDK: 105093162(IL5RA)
BACU: 103006352(IL5RA)
LVE: 103084009(IL5RA)
OOR: 101277768(IL5RA)
DLE: 111174176(IL5RA)
PCAD: 102990857(IL5RA)
ECB: 100060212(IL5RA)
EPZ: 103550188(IL5RA)
EAI: 106848474(IL5RA)
MYB: 102260961(IL5RA)
MYD: 102756146(IL5RA)
MMYO: 118668400(IL5RA)
MNA: 107529138(IL5RA)
HAI: 109373891(IL5RA)
DRO: 112309991(IL5RA)
SHON: 118989401(IL5RA)
AJM: 119036655(IL5RA)
MMF: 118633070(IL5RA)
PALE: 102896000(IL5RA)
PGIG: 120581941(IL5RA)
RAY: 107501729(IL5RA)
MJV: 108390628(IL5RA)
LAV: 100662380(IL5RA)
TMU: 101341114
MDO: 100022206(IL5RA)
SHR: 100916709(IL5RA)
PCW: 110195632(IL5RA)
OAA: 100093035(IL5RA)
GGA: 771801(IL5RA)
PCOC: 116236832(IL5RA)
MGP: 104913203(IL5RA)
CJO: 107319741(IL5RA)
NMEL: 110404916(IL5RA)
APLA: 101792942 101793158(IL5RA)
ACYG: 106035751 106036757(IL5RA)
TGU: 101233761(IL5RA) 115495938
LSR: 110469860(IL5RA) 110479348
SCAN: 103823698(IL5RA)
PMOA: 120495623(IL5RA) 120510180
GFR: 102034072(IL5RA)
FAB: 101812648(IL5RA)
PHI: 102105362(IL5RA) 106629157
PMAJ: 107201466 107210395(IL5RA)
CCAE: 111934940(IL5RA) 111944534
CCW: 104683514(IL5RA)
ETL: 114066999 114069375(IL5RA)
FPG: 101916270(IL5RA) 106112114
FCH: 102055672(IL5RA) 106631141
CLV: 102088450(IL5RA)
EGZ: 104132672(IL5RA)
NNI: 104016942(IL5RA)
ACUN: 113484858(IL5RA)
PADL: 103922494(IL5RA)
AAM: 106497360(IL5RA)
NPD: 112944095(IL5RA)
ASN: 102382488(IL5RA)
AMJ: 102574352(IL5RA)
CPOO: 109311448(IL5RA)
GGN: 109288956(IL5RA)
PSS: 102454412(IL5RA) 102457584
CMY: 102940083(IL5RA)
CPIC: 101938872 101948104(IL5RA)
TST: 117880929(IL5RA)
CABI: 116827037(IL5RA)
XLA: 108707982 108709068 108715845(il5ra.S) 447644(il5ra.L)
XTR: 100144707(il5ra) 101731623
PHYP: 113537654
AMEX: 103034286
EEE: 113577390
MZE: 101478279
XMA: 111608997
XCO: 114146577
PRET: 103478933
MALB: 109974072
SASA: 106600202
OTW: 112259935
SNH: 120020197
ELS: 105021249
CMK: 103177098(il3ra) 103177099
RTP: 109918309
 » show all
Reference
  Authors
Tavernier J, Van der Heyden J, Verhee A, Brusselle G, Van Ostade X, Vandekerckhove J, North J, Rankin SM, Kay AB, Robinson DS
  Title
Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit.
  Journal
Blood 95:1600-7 (2000)
  Sequence
[hsa:3568]
LinkDB

KEGG   ORTHOLOGY: K05055
Entry
K05055                      KO                                     

Symbol
IL6R, CD126
Name
interleukin 6 receptor
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04066  HIF-1 signaling pathway
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map04659  Th17 cell differentiation
map04932  Non-alcoholic fatty liver disease
map05163  Human cytomegalovirus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
Disease
H01968  Hyper-IgE syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04066 HIF-1 signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04151 PI3K-Akt signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05055  IL6R, CD126; interleukin 6 receptor
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05055  IL6R, CD126; interleukin 6 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05055  IL6R, CD126; interleukin 6 receptor
   04659 Th17 cell differentiation
    K05055  IL6R, CD126; interleukin 6 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05055  IL6R, CD126; interleukin 6 receptor
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K05055  IL6R, CD126; interleukin 6 receptor
   05163 Human cytomegalovirus infection
    K05055  IL6R, CD126; interleukin 6 receptor
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K05055  IL6R, CD126; interleukin 6 receptor
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05055  IL6R, CD126; interleukin 6 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05055  IL6R, CD126; interleukin 6 receptor
   04090 CD molecules
    K05055  IL6R, CD126; interleukin 6 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05055  IL6R, CD126; interleukin 6 receptor
CD molecules [BR:ko04090]
 Proteins
  K05055  CD126, IL6R; interleukin 6 receptor
Other DBs
GO: 0004915
Genes
HSA: 3570(IL6R)
PTR: 469506(IL6R)
PPS: 100972031(IL6R)
GGO: 101130311(IL6R)
PON: 100459702(IL6R)
NLE: 100604063(IL6R)
MCC: 716690(IL6R)
MCF: 102116430(IL6R)
CSAB: 103223920(IL6R)
CATY: 105593544(IL6R)
PANU: 101024850(IL6R)
RRO: 104663493(IL6R)
RBB: 108526613(IL6R)
TFN: 117075908(IL6R)
PTEH: 111543722(IL6R)
CJC: 100385661(IL6R)
SBQ: 101037958(IL6R)
MMUR: 105873204(IL6R)
MMU: 16194(Il6ra)
MCAL: 110291421(Il6r)
MPAH: 110320682(Il6r)
RNO: 24499(Il6r)
MCOC: 116093191(Il6r)
MUN: 110554248(Il6r)
CGE: 100750971(Il6r)
PLEU: 114707920(Il6r)
NGI: 103751364(Il6r)
HGL: 101704925(Il6r)
CCAN: 109688039(Il6r)
OCU: 100347752(IL6R)
TUP: 102492996(IL6R)
CFA: 612271(IL6R)
VVP: 112918888(IL6R)
VLG: 121488271(IL6R)
AML: 100471277(IL6R)
UMR: 103668717(IL6R)
UAH: 113245310(IL6R)
ORO: 101368251(IL6R)
ELK: 111138952
MPUF: 101676719(IL6R)
EJU: 114198669(IL6R)
MLX: 118013760(IL6R)
FCA: 101085689(IL6R)
PYU: 121015466(IL6R)
PTG: 102951407(IL6R)
PPAD: 109256188(IL6R)
AJU: 106987238(IL6R)
HHV: 120221504(IL6R)
BTA: 507359(IL6R)
BOM: 102287439(IL6R)
BIU: 109554138(IL6R)
BBUB: 102411639(IL6R)
CHX: 102179824(IL6R)
OAS: 101103369(IL6R)
ODA: 120855765(IL6R)
CCAD: 122432986(IL6R)
SSC: 399522(IL6R)
CFR: 102511771(IL6R)
CBAI: 105068250(IL6R)
CDK: 105089663(IL6R)
BACU: 103019388(IL6R)
LVE: 103078095(IL6R)
OOR: 101274728(IL6R)
DLE: 111167075(IL6R)
PCAD: 102994451(IL6R)
ECB: 102148787(IL6R)
EPZ: 103555416(IL6R)
EAI: 106828529(IL6R)
MYB: 102242151(IL6R)
MYD: 102757197(IL6R)
MMYO: 118672712(IL6R)
MNA: 107543721(IL6R)
HAI: 109373511(IL6R)
DRO: 112315493(IL6R)
SHON: 118990189(IL6R)
AJM: 119061811(IL6R)
MMF: 118637082(IL6R)
PALE: 102878027(IL6R)
PGIG: 120592175(IL6R)
RAY: 107504721(IL6R) 107509418
MJV: 108393946(IL6R)
TOD: 119236842(IL6R)
LAV: 100664198(IL6R)
TMU: 101356003
MDO: 100020561(IL6R)
SHR: 100924664(IL6R)
PCW: 110211977(IL6R)
OAA: 114808214(IL6R)
GGA: 693252(IL6R)
PCOC: 116237333(IL6R)
MGP: 104917170(IL6R)
CJO: 107324499(IL6R)
APLA: 113840022(IL6R)
TGU: 100231725(IL6R)
LSR: 110471522(IL6R)
SCAN: 103824053(IL6R)
PMOA: 120498906(IL6R)
GFR: 102038301(IL6R)
FAB: 101821627(IL6R)
PHI: 102105213(IL6R)
PMAJ: 107214583(IL6R)
CCAE: 111939461(IL6R)
ETL: 114068440(IL6R)
FPG: 101910354(IL6R)
FCH: 102050149(IL6R)
NPD: 112955205(IL6R)
AMJ: 102569548(IL6R)
CMY: 102929351(IL6R)
CPIC: 101947969(IL6R)
TST: 117888889(IL6R)
CABI: 116832734(IL6R)
ACS: 103281452(il6r)
PVT: 110081055(IL6R)
PBI: 103050892(IL6R)
TSR: 106546959(IL6R)
PMUA: 114587119(IL6R)
ZVI: 118076099(IL6R)
GJA: 107117068(IL6R)
XLA: 108699613(il6r.L) 108700406(il6r.S)
XTR: 100491081(il6r)
NPR: 108802740(IL6R)
DRE: 100135755(il6r)
IPU: 108266000(IL6R) 108266011
PHYP: 113542498(il6r)
AMEX: 103028913(il6r)
EEE: 113575234
TRU: 101069438
LCO: 104934469
NCC: 104959175
CGOB: 115021636
ELY: 117266211(il6r)
PLEP: 121945561(il6r)
SLUC: 116049531(il6r)
ECRA: 117946836(il6r)
GAT: 120810913(il6r)
MSAM: 119897611(il6r)
CUD: 121513002(il6r)
MZE: 101486162
ONL: 100702023
OAU: 116315690(il6r)
OLA: 101173653
OML: 112143872(il6r)
XMA: 102233430
XCO: 114142297
XHE: 116717491
PRET: 103478148
CTUL: 119786688(il6r)
KMR: 108241027(il6r)
ALIM: 106518420
AOCE: 111562998
CSEM: 103388203
POV: 109633010
LCF: 108885967
SDU: 111237206
XGL: 120784550(il6r)
HCQ: 109529023
BPEC: 110163064
MALB: 109964080
SASA: 100380426(il6ra) 106595086(IL6RA)
OMY: 101268967(il6r)
ELS: 105024482
SFM: 108923935(il6r)
AANG: 118221218(il6r)
PSPA: 121306967(il6r)
ARUT: 117395324(il6r)
LCM: 102359769(IL6R)
CMK: 103172814(il6r)
 » show all
Reference
PMID:1872801
  Authors
Schooltink H, Stoyan T, Lenz D, Schmitz H, Hirano T, Kishimoto T, Heinrich PC, Rose-John S
  Title
Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.
  Journal
Biochem J 277 ( Pt 3):659-64 (1991)
DOI:10.1042/bj2770659
  Sequence
[hsa:3570]
LinkDB

KEGG   ORTHOLOGY: K05072
Entry
K05072                      KO                                     

Symbol
IL7R, CD127
Name
interleukin 7 receptor
Pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04151  PI3K-Akt signaling pathway
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map05200  Pathways in cancer
map05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04068 FoxO signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04151 PI3K-Akt signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05072  IL7R, CD127; interleukin 7 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05072  IL7R, CD127; interleukin 7 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05072  IL7R, CD127; interleukin 7 receptor
  09163 Immune disease
   05340 Primary immunodeficiency
    K05072  IL7R, CD127; interleukin 7 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05072  IL7R, CD127; interleukin 7 receptor
   04090 CD molecules
    K05072  IL7R, CD127; interleukin 7 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05072  IL7R, CD127; interleukin 7 receptor
CD molecules [BR:ko04090]
 Proteins
  K05072  CD127, IL7R; interleukin 7 receptor
Other DBs
GO: 0004917
Genes
HSA: 3575(IL7R)
PTR: 461922(IL7R)
PPS: 100981232(IL7R)
GGO: 101140372(IL7R)
PON: 100461835(IL7R)
NLE: 100583768(IL7R)
MCC: 699869(IL7R)
MCF: 102143679(IL7R)
CSAB: 103215123(IL7R)
CATY: 105583419(IL7R)
PANU: 100997339(IL7R)
RRO: 104662030(IL7R)
RBB: 108533533(IL7R)
TFN: 117065018(IL7R)
PTEH: 111545525(IL7R)
CJC: 100397720(IL7R)
SBQ: 101044161(IL7R)
MMUR: 105855452(IL7R)
MMU: 16197(Il7r)
MCAL: 110310926(Il7r)
MPAH: 110329173(Il7r)
RNO: 294797(Il7r)
MCOC: 116083490(Il7r)
MUN: 110542896(Il7r)
CGE: 100757700(Il7r)
PLEU: 114710803(Il7r)
NGI: 103741311(Il7r)
HGL: 101710077(Il7r)
CCAN: 109698833(Il7r)
OCU: 100343726(IL7R)
TUP: 102499643(IL7R)
CFA: 612582(IL7R)
VVP: 112933551(IL7R)
VLG: 121486166(IL7R)
AML: 100477617(IL7R)
UMR: 103664716(IL7R)
UAH: 113260884(IL7R)
ORO: 101385299(IL7R)
ELK: 111141253
MPUF: 101686489(IL7R)
EJU: 114204719(IL7R)
FCA: 101100697(IL7R)
PYU: 121043454(IL7R)
PTG: 102953956(IL7R)
PPAD: 109267711(IL7R)
AJU: 106979009(IL7R)
HHV: 120242483(IL7R)
BTA: 521554(IL7R)
BOM: 102284629(IL7R)
BIU: 109575020(IL7R)
BBUB: 102400952(IL7R)
CHX: 102175248(IL7R)
OAS: 101111126(IL7R)
ODA: 120879335(IL7R)
CCAD: 122454504(IL7R)
SSC: 100271930(IL7R)
CFR: 102515501(IL7R)
CBAI: 105069416(IL7R)
CDK: 105087002(IL7R)
BACU: 103010049(IL7R)
LVE: 103089375(IL7R)
OOR: 101275057(IL7R)
DLE: 111187554(IL7R)
PCAD: 102992873(IL7R)
EPZ: 103545416(IL7R)
EAI: 106824753(IL7R)
MYB: 102264253(IL7R)
MYD: 102772772(IL7R)
MMYO: 118656297(IL7R)
MNA: 107546370(IL7R)
HAI: 109376825(IL7R)
DRO: 112321141(IL7R)
SHON: 118998771(IL7R)
AJM: 119036993(IL7R)
MMF: 118641726(IL7R)
PALE: 102889092(IL7R)
PGIG: 120586196(IL7R)
RAY: 107509706(IL7R)
MJV: 108406858(IL7R)
TOD: 119261071(IL7R)
LAV: 100671266(IL7R)
TMU: 101351100
MDO: 100020565(IL7R)
SHR: 100915478(IL7R)
PCW: 110214720(IL7R)
OAA: 100078445(IL7R)
GGA: 426054(IL7R)
PCOC: 116238618(IL7R)
MGP: 100542453(IL7R)
CJO: 107305872(IL7R)
NMEL: 110389974(IL7R)
APLA: 101800042(IL7R)
ACYG: 106036382(IL7R)
TGU: 100226205(IL7R)
LSR: 110482656(IL7R)
SCAN: 103821063(IL7R)
PMOA: 120502476(IL7R)
GFR: 102033898(IL7R)
FAB: 101816330(IL7R)
PHI: 102109259(IL7R)
PMAJ: 107216341(IL7R)
CCAE: 111940971(IL7R)
CCW: 104686602(IL7R)
ETL: 114066153(IL7R)
FPG: 101911430(IL7R)
FCH: 102052979(IL7R)
CLV: 102085807(IL7R)
EGZ: 104133924(IL7R)
NNI: 104018643(IL7R)
ACUN: 113489797(IL7R)
PADL: 103921479(IL7R)
AAM: 106499523(IL7R)
NPD: 112945900(IL7R)
ASN: 102368640(IL7R)
AMJ: 102558184(IL7R)
CPOO: 109307831(IL7R)
GGN: 109297899(IL7R)
PSS: 102449770(IL7R)
CMY: 102932302(IL7R)
CPIC: 101937386(IL7R)
TST: 117879238(IL7R)
CABI: 116824571(IL7R)
ACS: 103279695(il7r)
PVT: 110080088(IL7R)
PBI: 103058565(IL7R)
PMUR: 107297967(IL7R)
TSR: 106551942(IL7R)
PGUT: 117679991(IL7R)
PMUA: 114606663(IL7R)
ZVI: 118077302(IL7R)
GJA: 107108287(IL7R)
XTR: 116408012(il7r)
DRE: 100134973(il7r)
IPU: 108279371(il7r)
PHYP: 113541790(il7r)
AMEX: 103047579(il7r)
EEE: 113573243(il7r)
TRU: 101078727(il7r)
LCO: 104936386(il7r)
ELY: 117270145(il7r)
PLEP: 121960269(il7r)
SLUC: 116057125(il7r)
ECRA: 117958974(il7r)
PFLV: 114570789(il7r)
GAT: 120814760(il7r)
MZE: 101477974(il7r)
ONL: 102082329(il7r)
OAU: 116321284(il7r)
OLA: 110013505(il7r)
OML: 112136155
XMA: 102218066(il7r)
XCO: 114150235(il7r)
XHE: 116723975(il7r)
PRET: 103474046
CVG: 107095097(il7r)
CTUL: 119780469(il7r)
NFU: 107374989(il7r)
KMR: 108245570(il7r)
ALIM: 106527579
CSEM: 103390387
SDU: 111238700(il7r)
SLAL: 111652916(il7r)
XGL: 120806671(il7r)
HCQ: 109523342(il7r)
BPEC: 110161723(il7r)
MALB: 109973109(il7r)
OTW: 112219510 112257526(il7r)
OMY: 101268945 110523781(il7r)
SALP: 111961414 111982155(il7r)
ELS: 105014762(il7r)
SFM: 108932322(il7r)
PKI: 111842105
AANG: 118212890(il7r)
LOC: 107076551(il7r)
ARUT: 117409050(il7r) 117421234
 » show all
Reference
PMID:2317865
  Authors
Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al.
  Title
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
  Journal
Cell 60:941-51 (1990)
DOI:10.1016/0092-8674(90)90342-C
  Sequence
[hsa:3575]
Reference
PMID:8266077
  Authors
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ
  Title
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.
  Journal
Science 262:1877-80 (1993)
DOI:10.1126/science.8266077
LinkDB

KEGG   ORTHOLOGY: K05073
Entry
K05073                      KO                                     

Symbol
IL9R, CD129
Name
interleukin 9 receptor
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05073  IL9R, CD129; interleukin 9 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05073  IL9R, CD129; interleukin 9 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05073  IL9R, CD129; interleukin 9 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05073  IL9R, CD129; interleukin 9 receptor
   04090 CD molecules
    K05073  IL9R, CD129; interleukin 9 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05073  IL9R, CD129; interleukin 9 receptor
CD molecules [BR:ko04090]
 Proteins
  K05073  CD129, IL9R; interleukin 9 receptor
Other DBs
GO: 0004919
Genes
HSA: 3581(IL9R)
PPS: 100991889(IL9R)
GGO: 101126682 101131507 109027695(IL9R)
PON: 100461113(IL9R)
NLE: 100582570(IL9R) 115830471
MCC: 704266(IL9R)
MCF: 102136616(IL9R)
CSAB: 103232867(IL9R)
CATY: 105575884(IL9R) 105601185
PANU: 101010376(IL9R)
RRO: 104659540(IL9R) 104669797
RBB: 108530577
TFN: 117078006(IL9R)
PTEH: 111528183(IL9R)
CJC: 100408034(IL9R)
SBQ: 101038590(IL9R)
MMUR: 105856248(IL9R)
MMU: 16199(Il9r)
MCAL: 110305885(Il9r)
MPAH: 110332526(Il9r)
RNO: 24500(Il9r)
MCOC: 116078001(Il9r)
MUN: 110561264(Il9r)
CGE: 100759467(Il9r)
PLEU: 114709504
NGI: 103748240(Il9r)
HGL: 101723734(Il9r)
CCAN: 109702442(Il9r)
OCU: 100356855(IL9R)
TUP: 102499853(IL9R)
CFA: 100684807
VLG: 121482723(IL9R) 121486441
AML: 105238043(IL9R)
ORO: 101375181(IL9R)
ELK: 111156295
MPUF: 101671496(IL9R)
EJU: 114215706(IL9R)
MLX: 118021973(IL9R)
FCA: 101098275(IL9R)
PYU: 121019804(IL9R)
PTG: 102971955(IL9R)
PPAD: 109261185(IL9R)
AJU: 106977350(IL9R)
HHV: 120225182(IL9R)
BTA: 618294(IL9R)
BOM: 102284739
BIU: 109578826
BBUB: 102399583(IL9R)
CHX: 102191479(IL9R)
ODA: 120882220
CCAD: 122436524
SSC: 100521616(IL9R)
CFR: 102517268(IL9R)
CBAI: 105065756(IL9R)
CDK: 105098408(IL9R)
BACU: 103013363(IL9R)
LVE: 103080024(IL9R)
OOR: 101282073(IL9R)
DLE: 111185080(IL9R)
PCAD: 102995650(IL9R)
ECB: 100066258(IL9R)
EPZ: 103563129(IL9R)
EAI: 106836147
MYB: 102264245(IL9R)
MYD: 102771551(IL9R)
MMYO: 118652896(IL9R)
MNA: 107539642(IL9R)
HAI: 109385813(IL9R)
DRO: 112298507(IL9R)
SHON: 118978841(IL9R)
AJM: 119058278(IL9R)
MMF: 118642166
PALE: 102883479
PGIG: 120620495(IL9R)
RAY: 107506024
MJV: 108402039(IL9R)
TOD: 119242406(IL9R)
LAV: 100654245(IL9R)
TMU: 101359535
MDO: 103093950
SHR: 105749532
PCW: 110221831
OAA: 103165800
GGA: 416587(IL9R)
PCOC: 116237444
MGP: 104913392
CJO: 107320544
NMEL: 110405648
APLA: 101800880
ACYG: 106046046
SCAN: 108962293
PMOA: 120513205
GFR: 102032791
FAB: 101813255
PHI: 106628184
PMAJ: 107211001
CCAE: 111936218
CCW: 104684906
ETL: 114061438
FPG: 106112243
FCH: 106630798
CLV: 106145765
ACUN: 113485922
AAM: 106486127
NPD: 112959973
ASN: 106723064
AMJ: 106737976
CPOO: 109314782
PSS: 102463080
CMY: 102948367
TST: 117883820
CABI: 116830033
ACS: 107983616
PVT: 110085001
PBI: 112542849
PGUT: 117667343
PMUA: 114584677
ZVI: 118093019
GJA: 107106229
PLEP: 121945091
SLUC: 116036139
ECRA: 117946851
GAT: 120810704
OAU: 116315389
OLA: 105356042
OML: 112136505
XHE: 116715786
CVG: 107101598
CTUL: 119780944
SLAL: 111655655
XGL: 120784474
SFM: 108923897
ARUT: 117417679
 » show all
Reference
PMID:1376929
  Authors
Renauld JC, Druez C, Kermouni A, Houssiau F, Uyttenhove C, Van Roost E, Van Snick J
  Title
Expression cloning of the murine and human interleukin 9 receptor cDNAs.
  Journal
Proc Natl Acad Sci U S A 89:5690-4 (1992)
DOI:10.1073/pnas.89.12.5690
  Sequence
[hsa:3581]
Reference
  Authors
Knoops L, Renauld JC
  Title
IL-9 and its receptor: from signal transduction to tumorigenesis.
  Journal
Growth Factors 22:207-15 (2004)
DOI:10.1080/08977190410001720879
LinkDB

KEGG   ORTHOLOGY: K05134
Entry
K05134                      KO                                     

Symbol
IL10RA, CD210A
Name
interleukin 10 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04630  JAK-STAT signaling pathway
map05145  Toxoplasmosis
map05152  Tuberculosis
map05163  Human cytomegalovirus infection
Disease
H00286  Crohn disease
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
   04090 CD molecules
    K05134  IL10RA, CD210A; interleukin 10 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05134  IL10RA, CD210A; interleukin 10 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05134  CD210, IL10RA; interleukin 10 receptor, alpha
Other DBs
GO: 0004920
Genes
HSA: 3587(IL10RA)
PTR: 451580(IL10RA)
PPS: 100982658(IL10RA)
GGO: 101153778(IL10RA)
PON: 100436549(IL10RA)
NLE: 100607499(IL10RA)
MCC: 704383(IL10RA)
MCF: 102127536(IL10RA)
CSAB: 103248571(IL10RA)
CATY: 105582462(IL10RA)
PANU: 101014353(IL10RA)
RRO: 104665564(IL10RA)
RBB: 108536390(IL10RA)
TFN: 117081397(IL10RA)
PTEH: 111540195(IL10RA)
CJC: 100396693(IL10RA)
SBQ: 101032801(IL10RA)
MMUR: 105876063(IL10RA)
MMU: 16154(Il10ra)
MCAL: 110301830(Il10ra)
MPAH: 110327772(Il10ra)
RNO: 117539(Il10ra)
MCOC: 116072687(Il10ra)
MUN: 110549113(Il10ra)
CGE: 100762009(Il10ra)
PLEU: 114691198(Il10ra)
NGI: 103748335(Il10ra)
HGL: 101706532(Il10ra)
CCAN: 109694495(Il10ra)
OCU: 100354902(IL10RA)
TUP: 102502932(IL10RA)
CFA: 610823(IL10RA)
VVP: 112920163(IL10RA)
VLG: 121501031(IL10RA)
AML: 100469546(IL10RA)
UMR: 103662345(IL10RA)
UAH: 113260009(IL10RA)
ORO: 101383452(IL10RA)
ELK: 111153726
MPUF: 101672104(IL10RA)
EJU: 114211365(IL10RA)
MLX: 118013275(IL10RA)
FCA: 101087601(IL10RA)
PYU: 121035453(IL10RA)
PTG: 102957778(IL10RA)
PPAD: 109278578(IL10RA)
AJU: 106966240(IL10RA)
HHV: 120229995(IL10RA)
BTA: 513478(IL10RA)
BOM: 102274768(IL10RA)
BIU: 109569863(IL10RA)
BBUB: 102393529(IL10RA)
CHX: 102188959(IL10RA)
OAS: 101120946(IL10RA)
ODA: 120876296(IL10RA)
CCAD: 122449994(IL10RA)
SSC: 100525654(IL10RA)
CFR: 102520477(IL10RA)
CBAI: 105067828(IL10RA)
CDK: 105090182(IL10RA)
BACU: 103000998(IL10RA)
LVE: 103072948(IL10RA)
OOR: 101281088(IL10RA)
DLE: 111166949(IL10RA)
PCAD: 102975019(IL10RA)
ECB: 100071172(IL10RA)
EPZ: 103546683(IL10RA)
EAI: 106840268(IL10RA)
MYB: 102247681(IL10RA)
MYD: 102764914(IL10RA)
MMYO: 118664250(IL10RA)
MNA: 107530781(IL10RA)
HAI: 109385272(IL10RA)
DRO: 112314321(IL10RA)
SHON: 118994773(IL10RA)
AJM: 119050769(IL10RA)
MMF: 118628845(IL10RA)
PALE: 102890810(IL10RA)
PGIG: 120622040(IL10RA)
RAY: 107516126(IL10RA)
MJV: 108390189(IL10RA)
TOD: 119240719(IL10RA)
LAV: 100677387(IL10RA)
TMU: 101360959
MDO: 100031533(IL10RA)
SHR: 100926905(IL10RA)
PCW: 110207176(IL10RA)
OAA: 103167426(IL10RA)
GGA: 419771(IL10RA)
PCOC: 116233168(IL10RA)
MGP: 100545137(IL10RA)
CJO: 107324258(IL10RA)
NMEL: 110387594(IL10RA)
APLA: 101794038(IL10RA)
ACYG: 106039834(IL10RA)
TGU: 100217694(IL10RA)
LSR: 110470452(IL10RA)
SCAN: 103823016(IL10RA)
PMOA: 120508479(IL10RA)
FAB: 101818206(IL10RA)
PHI: 102101298(IL10RA)
PMAJ: 107214475(IL10RA)
CCAE: 111943508
CCW: 104692064(IL10RA)
ETL: 114056278(IL10RA)
FPG: 101924796(IL10RA)
FCH: 102057173(IL10RA)
CLV: 102087566(IL10RA)
EGZ: 104124566(IL10RA)
NNI: 104019035(IL10RA)
ACUN: 113488460
PADL: 103921561(IL10RA)
AAM: 106491541(IL10RA)
NPD: 112948085(IL10RA)
ASN: 102386718(IL10RA)
AMJ: 102573409(IL10RA)
CPOO: 109315431(IL10RA)
GGN: 109293670(IL10RA)
PSS: 102456819(IL10RA)
CMY: 102939733(IL10RA)
CPIC: 101938744(IL10RA)
TST: 117868656(IL10RA)
CABI: 116822949(IL10RA)
ACS: 103281396(il10ra)
PVT: 110079258(IL10RA)
PBI: 103067073(IL10RA)
PMUR: 114922354(IL10RA)
TSR: 106540631(IL10RA)
PGUT: 117670178(IL10RA)
PMUA: 114585708(IL10RA)
ZVI: 118096811
GJA: 107116775(IL10RA)
XLA: 108696462(il10ra.L) 108697595(il10ra.S)
XTR: 100145248(il10ra)
NPR: 108792158(IL10RA)
TRU: 101073224
LCO: 104918008
NCC: 104965921
CGOB: 115018172
ELY: 117259476(il10ra)
PLEP: 121943814(il10ra)
SLUC: 116047764(il10ra)
ECRA: 117941923(il10ra)
PFLV: 114552704
GAT: 120827311(il10ra)
MSAM: 119882604(il10ra)
CUD: 121516236(il10ra)
MZE: 101476951
ONL: 100693806
OAU: 116314740(il10ra)
OLA: 101165828
OML: 112149025(il10ra)
XMA: 102227526
XCO: 114133570
XHE: 116708199
PRET: 103474604
CTUL: 119792100(il10ra)
NFU: 107380316
KMR: 108243507(il10ra)
ALIM: 106515393
CSEM: 103378439
POV: 109630165
LCF: 108895270
SDU: 111228022
SLAL: 111655973
XGL: 120792413(il10ra)
HCQ: 109526362
MALB: 109960179
SASA: 106612744
OMY: 101268946(il10r1) 110507445
SNH: 120018393(il10ra) 120028953
ELS: 105012332
PKI: 111854950
AANG: 118210399(il10ra)
LOC: 107075710
PSPA: 121304049(il10ra)
LCM: 106703946(IL10RA)
 » show all
Reference
PMID:8120391
  Authors
Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW
  Title
Expression cloning and characterization of a human IL-10 receptor.
  Journal
J Immunol 152:1821-9 (1994)
  Sequence
[hsa:3587]
Reference
  Authors
Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H
  Title
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.
  Journal
J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117
LinkDB

KEGG   ORTHOLOGY: K05135
Entry
K05135                      KO                                     

Symbol
IL10RB, CD210B
Name
interleukin 10 receptor beta
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04630  JAK-STAT signaling pathway
map05145  Toxoplasmosis
map05152  Tuberculosis
map05163  Human cytomegalovirus infection
Disease
H00286  Crohn disease
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
   04090 CD molecules
    K05135  IL10RB, CD210B; interleukin 10 receptor beta
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05135  IL10RB, CD210B; interleukin 10 receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05135  CDw210b, IL10RB; interleukin 10 receptor, beta
Other DBs
GO: 0004920
Genes
HSA: 3588(IL10RB)
PTR: 473966(IL10RB)
PPS: 100996136(IL10RB)
GGO: 101138228(IL10RB)
PON: 100442754(IL10RB)
NLE: 100583052(IL10RB)
MCC: 706012(IL10RB)
MCF: 102139461(IL10RB)
CSAB: 103216884(IL10RB)
CATY: 105575377(IL10RB)
PANU: 100137244(IL10RB)
RRO: 104658749(IL10RB)
RBB: 108536853(IL10RB)
TFN: 117095710(IL10RB)
PTEH: 111525297(IL10RB)
CJC: 100409946(IL10RB)
SBQ: 101035361
MMUR: 109729198(IL10RB)
MMU: 16155(Il10rb)
MCAL: 110311631(Il10rb)
MPAH: 110329837(Il10rb)
RNO: 304091(Il10rb)
MCOC: 116086125(Il10rb)
MUN: 110541906(Il10rb)
PLEU: 114698436(Il10rb)
NGI: 103736456(Il10rb)
HGL: 101723546(Il10rb)
CCAN: 109699946(Il10rb)
OCU: 100338351(IL10RB)
TUP: 102478893(IL10RB)
CFA: 478404(IL10RB)
VVP: 112909265(IL10RB)
VLG: 121479466(IL10RB)
AML: 109488333(IL10RB)
UMR: 103673110
UAH: 113264906
ORO: 101385813(IL10RB)
ELK: 111155723
MPUF: 101673399(IL10RB)
EJU: 114218044(IL10RB)
MLX: 118018830(IL10RB)
FCA: 101090038(IL10RB)
PYU: 121035997(IL10RB)
PTG: 102954576(IL10RB)
PPAD: 109249712(IL10RB)
AJU: 106966461(IL10RB)
HHV: 120229665(IL10RB)
BTA: 767864(IL10RB)
BOM: 102275508(IL10RB)
BIU: 109571300(IL10RB)
BBUB: 102394618(IL10RB)
CHX: 102174776(IL10RB)
OAS: 105609264(IL10RB)
ODA: 120854351(IL10RB)
CCAD: 122428758(IL10RB)
SSC: 396657(IL10RB)
CFR: 102524026(IL10RB)
CBAI: 105070235(IL10RB)
CDK: 105089870(IL10RB)
BACU: 103020986(IL10RB)
LVE: 103074739(IL10RB)
OOR: 101283710(IL10RB)
DLE: 111163875(IL10RB)
PCAD: 102990305(IL10RB)
ECB: 100052549(IL10RB)
EPZ: 103549156(IL10RB)
EAI: 106832842(IL10RB)
MYB: 102245672(IL10RB)
MYD: 102752206(IL10RB)
MMYO: 118676709(IL10RB)
MNA: 107537472
HAI: 109373232(IL10RB)
DRO: 112305545(IL10RB)
SHON: 119000286(IL10RB)
AJM: 119035736(IL10RB)
MMF: 118617730(IL10RB)
PALE: 102899031(IL10RB)
PGIG: 120598868(IL10RB)
RAY: 107519579(IL10RB)
MJV: 108409506(IL10RB)
TOD: 119257232(IL10RB)
LAV: 100667872(IL10RB)
TMU: 101361467
MDO: 100026691(IL10RB)
SHR: 100919327(IL10RB)
PCW: 110214852
OAA: 100083520(IL10RB)
GGA: 395663(IL10RB)
PCOC: 116242030(IL10RB)
MGP: 100539434(IL10RB)
CJO: 107322954(IL10RB)
NMEL: 110402444(IL10RB)
APLA: 101804501(IL10RB)
ACYG: 106043437(IL10RB)
TGU: 100227553(IL10RB)
LSR: 110474925
SCAN: 103824809
PMOA: 120499980
GFR: 102044482(IL10RB)
FAB: 101814256(IL10RB)
PMAJ: 107199700
CCAE: 111928928
CCW: 104698066(IL10RB)
ETL: 114071603
FPG: 101919585(IL10RB)
FCH: 102055084(IL10RB)
CLV: 102097541(IL10RB)
EGZ: 104128163(IL10RB)
NNI: 104020119(IL10RB)
ACUN: 113479022(IL10RB)
PADL: 103920314(IL10RB)
AAM: 106494971(IL10RB)
NPD: 112953618(IL10RB)
ASN: 102381669(IL10RB)
AMJ: 102566821(IL10RB)
CPOO: 109305775
GGN: 109303086(IL10RB)
PSS: 102462276(IL10RB)
CMY: 102929478(IL10RB)
CPIC: 101941799(IL10RB)
TST: 117867145(IL10RB)
CABI: 116820909(IL10RB)
ACS: 103281134(IL10R2)
PVT: 110080373(IL10RB)
PBI: 103065200(IL10RB)
PMUR: 107290621(IL10RB)
TSR: 106550466
PGUT: 117675794
PMUA: 114596049
ZVI: 118084975
GJA: 107110549(IL10RB)
XLA: 108707876(il10rb.L) 446849(il10rb.S)
XTR: 100329183(il10rb)
NPR: 108794148
DRE: 619391(il10rb) 797527(crfb4)
TRU: 101071473
ELY: 117251232(il10rb) 117251233
PLEP: 121948734(il10rb) 121948998
ECRA: 117952794(il10rb) 117952796
GAT: 120833748(il10rb) 120834221
OML: 112154772 112155444(il10rb)
CTUL: 119777364 119777366(il10rb)
KMR: 108251684(ifngr2) 108251685 108251687(il10rb)
CSEM: 103391493
XGL: 120801476(il10rb) 120801921
SASA: 106575150 106581741(CRFB4a) 106581895(CRFB5c) 106581896(CRFBx) 106586842(CRFB5a) 106586856(CRFB5b) 106586857(I10R2) 106586873(CRFB5a)
PKI: 111834132
LCM: 102345645(IL10RB)
 » show all
Reference
PMID:8314576
  Authors
Lutfalla G, Gardiner K, Uze G
  Title
A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR.
  Journal
Genomics 16:366-73 (1993)
DOI:10.1006/geno.1993.1199
  Sequence
[hsa:3588]
Reference
  Authors
Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H
  Title
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.
  Journal
J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117
LinkDB

KEGG   ORTHOLOGY: K05056
Entry
K05056                      KO                                     

Symbol
IL11RA
Name
interleukin 11 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
Disease
H02254  Craniosynostosis and dental anomalies
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05056  IL11RA; interleukin 11 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05056  IL11RA; interleukin 11 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05056  IL11RA; interleukin 11 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05056  IL11RA; interleukin 11 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05056  IL11RA; interleukin 11 receptor alpha
Other DBs
GO: 0004921
Genes
HSA: 3590(IL11RA)
PTR: 100616505(IL11RA)
PPS: 100976877(IL11RA)
GGO: 101128866(IL11RA)
PON: 100190822(IL11RA)
NLE: 100580609(IL11RA) 115830375
MCC: 700201(IL11RA)
MCF: 102133459(IL11RA)
CSAB: 103219253(IL11RA)
CATY: 105590039(GALT)
PANU: 101011618(IL11RA)
RRO: 104680015(IL11RA)
RBB: 108542167(IL11RA)
TFN: 117099035(IL11RA)
PTEH: 111536782(IL11RA)
CJC: 100894787(IL11RA)
SBQ: 101035136(IL11RA)
MMUR: 105874336(IL11RA)
MMU: 100042555(Gm13305) 16157(Il11ra1) 16158(Il11ra2)
MPAH: 110338645(Il11ra)
RNO: 245983(Il11ra1)
MCOC: 116095856(Il11ra)
MUN: 110547120(Il11ra)
CGE: 100752228(Il11ra)
PLEU: 114703228(Il11ra)
NGI: 103741561(Il11ra)
HGL: 101708949(Il11ra)
CCAN: 109694667(Il11ra)
OCU: 103351784(IL11RA)
CFA: 481588(IL11RA)
VVP: 112927526(IL11RA)
VLG: 121495699(IL11RA)
AML: 100481047(IL11RA)
UMR: 103667059(IL11RA)
UAH: 113260499(IL11RA)
ORO: 101373105(IL11RA)
ELK: 111145851
MPUF: 101685764(IL11RA)
EJU: 114218231(IL11RA)
MLX: 118017994(IL11RA)
FCA: 101085930(IL11RA)
PYU: 121034606(IL11RA)
PTG: 102961264(IL11RA)
PPAD: 109252006(IL11RA)
AJU: 106975637(IL11RA)
HHV: 120241734(IL11RA)
BTA: 508932(IL11RA)
BOM: 102277908(IL11RA)
BIU: 109563195(IL11RA)
BBUB: 102411074(IL11RA)
CHX: 102173566(IL11RA)
OAS: 101120724(IL11RA)
CCAD: 122431771(IL11RA)
SSC: 100524166(IL11RA)
CFR: 102523921(IL11RA)
CBAI: 105078769(IL11RA)
CDK: 105085599(IL11RA)
BACU: 103010081(IL11RA)
LVE: 103073382(IL11RA)
OOR: 101272521(IL11RA)
DLE: 111163143(IL11RA)
PCAD: 102983483(IL11RA)
ECB: 100068493(GALT)
EPZ: 103542631(GALT)
EAI: 106841405(GALT)
MYB: 102254635(IL11RA)
MYD: 102773607(IL11RA)
MMYO: 118667365(IL11RA)
MNA: 107545002(IL11RA)
HAI: 109371778(IL11RA)
DRO: 112304578(IL11RA)
SHON: 118979605(GALT)
AJM: 119053829(GALT)
MMF: 118629667(IL11RA)
PALE: 102892445(IL11RA)
RAY: 107502842(IL11RA)
MJV: 108395551(GALT)
TOD: 119230730(IL11RA)
LAV: 100655906(IL11RA)
TMU: 101357357
MDO: 100618445(IL11RA)
SHR: 100921841(GALT)
PCW: 110194547(IL11RA)
OAA: 100088696(IL11RA)
GGA: 693251(IL11RA)
PCOC: 116239223(IL11RA)
MGP: 100549907(IL11RA)
CJO: 107305834(IL11RA)
NMEL: 110390124(IL11RA)
ACYG: 106048603(IL11RA)
TGU: 100224274(IL11RA)
LSR: 110484167(IL11RA)
SCAN: 103822937(IL11RA)
PMOA: 120498244(IL11RA)
GFR: 102035247(IL11RA)
FAB: 101819200(IL11RA)
PHI: 102107250(IL11RA)
PMAJ: 107198469(IL11RA)
CCAE: 111941168(IL11RA)
CCW: 104686558(IL11RA)
ETL: 114069461(IL11RA)
FPG: 101922130(IL11RA)
FCH: 102048823(IL11RA)
CLV: 102088563(IL11RA)
EGZ: 104133881(IL11RA)
NNI: 104017598(IL11RA)
ACUN: 113489854(IL11RA)
PADL: 103925922(IL11RA)
AAM: 106492904(IL11RA)
NPD: 112947799(IL11RA)
ASN: 102370001(IL11RA)
AMJ: 102568502(IL11RA)
CPOO: 109307671(IL11RA)
GGN: 109297952(IL11RA)
CMY: 102946161(IL11RA)
CPIC: 101936077(IL11RA)
TST: 117879196(IL11RA)
CABI: 116818236(IL11RA)
ACS: 100560091(il11ra)
PVT: 110082815(IL11RA)
PBI: 103061645(IL11RA)
PMUR: 107300035(IL11RA)
PGUT: 117679748(IL11RA)
PMUA: 114606165(IL11RA)
ZVI: 118077310(IL11RA)
GJA: 107106345(IL11RA)
XLA: 108718839(il11ra.L)
XTR: 100101801(il11ra)
NPR: 108793592(IL11RA)
DRE: 334010(il11ra) 556326
SGH: 107554229
CCAR: 109097480
CAUA: 113109582
IPU: 108276979(IL11RA)
PHYP: 113544073
AMEX: 103023250
EEE: 113577628
TRU: 115250187
LCO: 104927707
NCC: 104948364
CGOB: 115016922
ELY: 117270026(il11ra)
PLEP: 121959728(il11ra)
SLUC: 116045144(il11ra)
ECRA: 117958951(il11ra)
PFLV: 114570622
GAT: 120831856(il11ra)
MSAM: 119914787(il11ra)
CUD: 121524991(il11ra)
MZE: 101484719
ONL: 100692513
OAU: 116330775(il11ra)
OLA: 101163752
OML: 112163102(il11ra)
XMA: 102218314
XCO: 114149981
XHE: 116724219
PRET: 103473532
CVG: 107091061
CTUL: 119772040(il11ra)
NFU: 107395225
KMR: 108232533(il11ra)
ALIM: 106513592
AOCE: 111581613
CSEM: 103390330
POV: 109640322
LCF: 108880301
SDU: 111239645
SLAL: 111655747
XGL: 120806827(il11ra)
HCQ: 109518308
BPEC: 110172339
MALB: 109960790
OMY: 110524930 110536851(il11ra)
SALP: 112076315
SNH: 120044755(il11ra)
ELS: 105026664
SFM: 108934716(il11ra)
PKI: 111842122
AANG: 118212566(il11ra)
LOC: 102691463
ARUT: 117409357(il11ra)
LCM: 102359053(IL11RA)
CMK: 103184882
RTP: 109918343
 » show all
Reference
PMID:7957045
  Authors
Hilton DJ, Hilton AA, Raicevic A, Rakar S, Harrison-Smith M, Gough NM, Begley CG, Metcalf D, Nicola NA, Willson TA
  Title
Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.
  Journal
EMBO J 13:4765-75 (1994)
DOI:10.1002/j.1460-2075.1994.tb06802.x
  Sequence
[mmu:16157]
Reference
  Authors
Grotzinger J
  Title
Molecular mechanisms of cytokine receptor activation.
  Journal
Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6
LinkDB

KEGG   ORTHOLOGY: K05063
Entry
K05063                      KO                                     

Symbol
IL12RB1, CD212
Name
interleukin 12 receptor beta-1
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04659 Th17 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04090 CD molecules
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
CD molecules [BR:ko04090]
 Proteins
  K05063  CD212, IL12RB1; interleukin 12 receptor, beta 1
Genes
HSA: 3594(IL12RB1)
PTR: 455851(IL12RB1)
PPS: 100979712(IL12RB1)
GGO: 101134933(IL12RB1)
PON: 100435478(IL12RB1)
NLE: 100605040(IL12RB1)
MCC: 574199(IL12RB1)
MCF: 102143359(IL12RB1)
CSAB: 103234165(IL12RB1)
CATY: 105601688(IL12RB1)
PANU: 101015690(IL12RB1)
RRO: 104680608(IL12RB1)
RBB: 108534277(IL12RB1)
TFN: 117074814(IL12RB1)
PTEH: 111554319(IL12RB1)
CJC: 100399291(IL12RB1)
SBQ: 101032718(IL12RB1)
MMU: 16161(Il12rb1)
MCAL: 110300406(Il12rb1)
MPAH: 110336813(Il12rb1)
RNO: 171333(Il12rb1)
MCOC: 116069495(Il12rb1)
MUN: 110549207(Il12rb1)
CGE: 100763378(Il12rb1)
NGI: 103726945(Il12rb1)
HGL: 101702338(Il12rb1)
CCAN: 109699530(Il12rb1)
TUP: 102470262(IL12RB1)
CFA: 484828(IL12RB1)
VVP: 112913171(IL12RB1)
VLG: 121495556(IL12RB1)
AML: 100474774(IL12RB1)
UMR: 103674947(IL12RB1)
UAH: 113256701(IL12RB1)
ORO: 101372587(IL12RB1)
ELK: 111144102
MPUF: 101682913(IL12RB1)
EJU: 114196409(IL12RB1)
MLX: 118005254(IL12RB1)
FCA: 101093085(IL12RB1)
PYU: 121011001(IL12RB1)
PTG: 102959877(IL12RB1)
PPAD: 109247602(IL12RB1)
AJU: 106969152(IL12RB1)
HHV: 120239142(IL12RB1)
BTA: 524299(IL12RB1)
BOM: 102286576(IL12RB1)
BIU: 109561420(IL12RB1)
BBUB: 102403765(IL12RB1)
CHX: 102172253(IL12RB1)
OAS: 101110054(IL12RB1)
ODA: 120864211(IL12RB1)
CCAD: 122440735(IL12RB1)
SSC: 100271900(IL12RB1)
CFR: 102512953(IL12RB1)
CBAI: 105082567(IL12RB1)
CDK: 105101865(IL12RB1)
BACU: 103009591(IL12RB1)
LVE: 103081698(IL12RB1)
OOR: 101281920(IL12RB1)
DLE: 111166653(IL12RB1)
PCAD: 102991223(IL12RB1)
ECB: 100146965(IL12RB1)
EPZ: 103561544(IL12RB1)
EAI: 106825010(IL12RB1)
MYB: 102253710(IL12RB1)
MYD: 102769690(IL12RB1)
MMYO: 118659126(IL12RB1)
MNA: 107535370(IL12RB1)
HAI: 109382356(IL12RB1)
DRO: 112305028(IL12RB1)
SHON: 118975125(IL12RB1)
AJM: 119046827(IL12RB1)
MMF: 118643823(IL12RB1)
PALE: 102878946(IL12RB1)
PGIG: 120606547(IL12RB1)
RAY: 107521689(IL12RB1)
MJV: 108383562(IL12RB1)
TOD: 119242236(IL12RB1)
LAV: 100672726(IL12RB1)
TMU: 101351266
MDO: 103105099(IL12RB1)
SHR: 105749415(IL12RB1)
PCW: 110223476(IL12RB1)
OAA: 100079998(IL12RB1)
GGA: 101749221(IL12RB1)
PCOC: 116235710(IL12RB1)
MGP: 104915407
CJO: 107325690(IL12RB1)
NMEL: 110388754(IL12RB1)
APLA: 101797086(IL12RB1)
ACYG: 106044936(IL12RB1)
TGU: 115490890(IL12RB1)
SCAN: 103822011(IL12RB1)
PMOA: 120498080(IL12RB1)
GFR: 102037576(IL12RB1)
FAB: 101812402(IL12RB1)
PHI: 102100998(IL12RB1)
PMAJ: 107215365(IL12RB1)
CCAE: 111940322(IL12RB1)
CCW: 104697031(IL12RB1)
ETL: 114069506(IL12RB1)
FPG: 101911543(IL12RB1)
FCH: 102051332(IL12RB1)
CLV: 102098000(IL12RB1)
EGZ: 104135651(IL12RB1)
NNI: 104018782(IL12RB1)
ACUN: 113489367(IL12RB1)
NPD: 112943885(IL12RB1)
ASN: 102378143(IL12RB1)
AMJ: 106737527(IL12RB1)
CPOO: 109312419(IL12RB1)
GGN: 109295058(IL12RB1)
PSS: 102461655(IL12RB1)
CMY: 114022446(IL12RB1)
CPIC: 101941042(IL12RB1)
TST: 117869099(IL12RB1)
CABI: 116826233(IL12RB1)
ACS: 103282283(il12rb1)
PVT: 110072563(IL12RB1)
PBI: 112540224(IL12RB1)
PMUR: 114922203(IL12RB1)
TSR: 106543464(IL12RB1)
PGUT: 117677413(IL12RB1)
PMUA: 114588688(IL12RB1)
ZVI: 118085976(IL12RB1)
XLA: 108720006
XTR: 100496683(il12rb1)
DRE: 101883301(si:dkey-13m1.2)
IPU: 108270768
PHYP: 113528465
AMEX: 103028625
TRU: 105417954
LCO: 104920404
NCC: 104959360(il12rb1)
CGOB: 115006624(il12rb1) 115007368
ELY: 117253726(il12rb1)
PLEP: 121962182(il12rb1)
SLUC: 116055332(il12rb1)
ECRA: 117950930(il12rb1)
PFLV: 114561835
GAT: 120824464(il12rb1)
MSAM: 119900530(il12rb1)
CUD: 121511673(il12rb1)
MZE: 101472333
ONL: 102077946
OAU: 116328448(il12rb1)
OLA: 105353921
OML: 112150641(il12rb1)
XMA: 111609789(il12rb1)
XCO: 114151489(il12rb1)
XHE: 116725976(il12rb1)
PRET: 103463422
CVG: 107099666(il12rb1)
CTUL: 119787640(il12rb1)
KMR: 108234318(il12rb1)
ALIM: 106519187
AOCE: 111576546
CSEM: 103395987
LCF: 108881184(il12rb1)
SDU: 111216416(il12rb1)
SLAL: 111669988(il12rb1)
XGL: 120790921(il12rb1)
HCQ: 109519017
BPEC: 110167972
MALB: 109966833
ELS: 105026196
SFM: 108930531(il12rb1)
AANG: 118224923(il12rb1)
LOC: 107079633(il12rb1)
PSPA: 121300621
ARUT: 117428961(il12rb1)
 » show all
Reference
PMID:8617302
  Authors
Wu CY, Warrier RR, Carvajal DM, Chua AO, Minetti LJ, Chizzonite R, Mongini PK, Stern AS, Gubler U, Presky DH, Gately MK
  Title
Biological function and distribution of human interleukin-12 receptor beta chain.
  Journal
Eur J Immunol 26:345-50 (1996)
DOI:10.1002/eji.1830260212
  Sequence
[hsa:3594]
Reference
PMID:7911493
  Authors
Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK, et al.
  Title
Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.
  Journal
J Immunol 153:128-36 (1994)
  Sequence
[hsa:3594]
LinkDB

KEGG   ORTHOLOGY: K05064
Entry
K05064                      KO                                     

Symbol
IL12RB2
Name
interleukin 12 receptor beta-2
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H01476  Behcet disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05064  IL12RB2; interleukin 12 receptor beta-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05064  IL12RB2; interleukin 12 receptor beta-2
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05064  IL12RB2; interleukin 12 receptor beta-2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05064  IL12RB2; interleukin 12 receptor beta-2
Genes
HSA: 3595(IL12RB2)
PTR: 469348(IL12RB2)
PPS: 100984257(IL12RB2)
GGO: 101144503(IL12RB2)
PON: 100456779(IL12RB2)
NLE: 100582797(IL12RB2)
MCC: 700677(IL12RB2)
MCF: 102131165(IL12RB2)
CSAB: 103224656(IL12RB2)
CATY: 105596063(IL12RB2)
PANU: 101012647(IL12RB2)
RRO: 104657309(IL12RB2)
RBB: 108532946(IL12RB2)
TFN: 117092067(IL12RB2)
PTEH: 111541128(IL12RB2)
CJC: 100393796(IL12RB2)
SBQ: 101048468(IL12RB2)
MMUR: 105872849(IL12RB2)
MMU: 16162(Il12rb2)
MCAL: 110296634(Il12rb2)
MPAH: 110316620(Il12rb2)
RNO: 171334(Il12rb2)
MCOC: 116099025(Il12rb2)
CGE: 100758602(Il12rb2)
PLEU: 114700924(Il12rb2)
NGI: 103743352(Il12rb2)
HGL: 101717608(Il12rb2)
CCAN: 109698313(Il12rb2)
OCU: 100350416(IL12RB2)
TUP: 102494666(IL12RB2)
CFA: 489550(IL12RB2)
VVP: 112907882(IL12RB2)
VLG: 121499494(IL12RB2)
AML: 100478166(IL12RB2)
UMR: 103663034(IL12RB2)
UAH: 113254551(IL12RB2)
ORO: 101376489(IL12RB2)
ELK: 111143098
MPUF: 101691811(IL12RB2)
EJU: 114208449(IL12RB2)
MLX: 118019291(IL12RB2)
FCA: 101088012(IL12RB2)
PYU: 121027280(IL12RB2)
PTG: 102953239(IL12RB2)
PPAD: 109266706(IL12RB2)
AJU: 106985194(IL12RB2)
HHV: 120232628(IL12RB2)
BTA: 282452(IL12RB2)
BOM: 102265420(IL12RB2)
BIU: 109556179(IL12RB2)
BBUB: 102403761(IL12RB2)
CHX: 102176287(IL12RB2)
OAS: 100820736(IL12RB2)
ODA: 120856565(IL12RB2)
CCAD: 122436848(IL12RB2)
SSC: 397178(IL12RB2)
CFR: 102523963(IL12RB2)
CBAI: 105075555(IL12RB2)
CDK: 105096624(IL12RB2)
BACU: 103019963(IL12RB2)
LVE: 103079416(IL12RB2)
OOR: 101283273(IL12RB2)
DLE: 111178439(IL12RB2)
PCAD: 102991572
ECB: 100053757(IL12RB2)
EPZ: 103561906(IL12RB2)
EAI: 106825064(IL12RB2)
MYB: 102240232(IL12RB2)
MYD: 102751523(IL12RB2)
MMYO: 118676249(IL12RB2)
MNA: 107533449(IL12RB2)
HAI: 109384960(IL12RB2)
DRO: 112309047(IL12RB2)
SHON: 118984685(IL12RB2)
AJM: 119063512(IL12RB2)
MMF: 118626554(IL12RB2)
PALE: 102885605(IL12RB2)
PGIG: 120583199(IL12RB2)
RAY: 107520563(IL12RB2)
MJV: 108404889(IL12RB2)
TOD: 119237082(IL12RB2)
LAV: 100666176(IL12RB2)
TMU: 101352491
MDO: 103105069(IL12RB2)
SHR: 100931154(IL12RB2)
PCW: 110212954(IL12RB2)
OAA: 100081756(IL12RB2)
GGA: 424705(IL12RB2)
PCOC: 116236320
MGP: 100540289
CJO: 107317747(IL12RB2)
NMEL: 110402621(IL12RB2)
APLA: 101791874(IL12RB2)
ACYG: 106043599(IL12RB2)
TGU: 115496184
LSR: 110473252
SCAN: 103815228
PMOA: 120503227(IL12RB2)
GFR: 102044094(IL12RB2)
FAB: 101814678(IL12RB2)
PHI: 102101267(IL12RB2)
PMAJ: 107207898(IL12RB2)
CCW: 104695495(IL12RB2)
ETL: 114061068(IL12RB2)
FPG: 101921709(IL12RB2)
FCH: 102052886(IL12RB2)
CLV: 102091062(IL12RB2)
EGZ: 104123868(IL12RB2)
NNI: 104009324
ACUN: 113483179(IL12RB2)
PADL: 103914046(IL12RB2)
AAM: 106486526(IL12RB2)
NPD: 112945538(IL12RB2)
ASN: 102373922(IL12RB2)
AMJ: 102576733(IL12RB2)
CPOO: 109307023(IL12RB2)
GGN: 109305423(IL12RB2)
PSS: 102452148(IL12RB2)
CMY: 102947382(IL12RB2)
CPIC: 101932982(IL12RB2)
TST: 117882272(IL12RB2)
CABI: 116819880(IL12RB2)
ACS: 103280214(il12rb2) 103281926
PVT: 110079852(IL12RB2)
PBI: 103053316(IL12RB2)
PMUR: 114923702(IL12RB2)
TSR: 106548941(IL12RB2)
PGUT: 117674973(IL12RB2)
PMUA: 114598875(IL12RB2)
ZVI: 118089129(IL12RB2)
GJA: 107114339(IL12RB2)
DRE: 100134971(il12rb2)
CCAR: 109093447
IPU: 108271892
PHYP: 113538213
AMEX: 103034527
EEE: 113570424
ELY: 117253460(il23r) 117253707(il12rb2)
PLEP: 121941367(il12rb2) 121941404(il23r)
SLUC: 116063206(il12rb2) 116063275(il23r)
ECRA: 117950525(il23r) 117950527(il12rb2)
GAT: 120824303(il23r) 120824304(il12rb2)
MSAM: 119900964(il23r) 119900965(il12rb2)
CUD: 121511979(il12rb2) 121511994(il23r)
OAU: 116327895(il23r) 116327918(il12rb2)
OML: 112150134(il23r) 112150552(il12rb2)
CTUL: 119790024(il23r) 119790026(il12rb2)
KMR: 108230530(il23r) 108230698(il12rb2)
ALIM: 106532034
XGL: 120790304(il12rb2) 120791057(il23r)
SASA: 100306791(i12r2) 106613945
OTW: 112251058
OMY: 110524480(il23r) 110524481(il12rb2)
SNH: 120054884(il23r) 120054885(il12rb2)
AANG: 118224836(il12rb2) 118225270(il23r)
LOC: 102696196(il12rb2) 107078386(il23r)
LCM: 102353471 102361820(IL27RA)
CMK: 103189128(il12rb2)
RTP: 109926856 109926857(il12rb2)
SDM: 118193652
 » show all
Reference
PMID:8943050
  Authors
Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U
  Title
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.
  Journal
Proc Natl Acad Sci U S A 93:14002-7 (1996)
DOI:10.1073/pnas.93.24.14002
  Sequence
[hsa:3595]
LinkDB

KEGG   ORTHOLOGY: K05076
Entry
K05076                      KO                                     

Symbol
IL13RA1, CD213A1
Name
interleukin 13 receptor alpha-1
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
   04090 CD molecules
    K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
CD molecules [BR:ko04090]
 Proteins
  K05076  CD213a1, IL13RA1; interleukin 13 receptor, alpha 1
Genes
HSA: 3597(IL13RA1)
PTR: 735671(IL13RA1)
PPS: 100967748(IL13RA1)
GGO: 101133803(IL13RA1)
PON: 100457694(IL13RA1)
NLE: 100579912(IL13RA1)
MCC: 710986(IL13RA1)
MCF: 102135058(IL13RA1)
CSAB: 103247319(IL13RA1)
CATY: 105598400(IL13RA1)
PANU: 101026802(IL13RA1)
RRO: 104664105(IL13RA1)
RBB: 108524412(IL13RA1)
TFN: 117078386(IL13RA1)
PTEH: 111531448(IL13RA1)
CJC: 100385087(IL13RA1)
SBQ: 101045372(IL13RA1)
MMUR: 105857233(IL13RA1)
MMU: 16164(Il13ra1)
MCAL: 110286727(Il13ra1)
MPAH: 110313659(Il13ra1)
RNO: 100360218 252963(Il13ra1)
MCOC: 116075762(Il13ra1)
MUN: 110566908(Il13ra1)
CGE: 100771375(Il13ra1)
PLEU: 114705427(Il13ra1)
NGI: 103743079(Il13ra1)
HGL: 101723721(Il13ra1)
CCAN: 109697802(Il13ra1)
OCU: 100351788(IL13RA1)
TUP: 102475660(IL13RA1)
CFA: 403623(IL13RA1)
VVP: 112910586(IL13RA1)
VLG: 121483052(IL13RA1)
AML: 100477299(IL13RA1)
UMR: 103677732(IL13RA1)
UAH: 113241264(IL13RA1)
ORO: 101371898(IL13RA1)
ELK: 111157297
MPUF: 101675848(IL13RA1)
EJU: 114196955(IL13RA1)
MLX: 118012311(IL13RA1)
FCA: 101091351(IL13RA1)
PYU: 121025428(IL13RA1)
PTG: 102949045(IL13RA1)
PPAD: 109250782(IL13RA1)
AJU: 106986087(IL13RA1)
HHV: 120239859(IL13RA1)
BTA: 407110(IL13RA1)
BOM: 102274749(IL13RA1)
BBUB: 102415410(IL13RA1)
CHX: 102171312(IL13RA1)
OAS: 443518(IL13RA1)
ODA: 120882590(IL13RA1)
CCAD: 122434813(IL13RA1)
SSC: 397615(IL13RA1)
CFR: 102509671(IL13RA1)
CBAI: 105062980(IL13RA1)
CDK: 105093924(IL13RA1)
BACU: 103011155(IL13RA1)
LVE: 103069593(IL13RA1)
OOR: 101284340(IL13RA1)
DLE: 111169041(IL13RA1)
PCAD: 102992458(IL13RA1)
ECB: 100055312(IL13RA1)
EPZ: 103542816(IL13RA1)
EAI: 106843797(IL13RA1)
MYB: 102240277(IL13RA1)
MYD: 102773525(IL13RA1)
MMYO: 118653704(IL13RA1)
MNA: 107529345(IL13RA1)
HAI: 109396202(IL13RA1)
DRO: 112303536(IL13RA1)
SHON: 118989853(IL13RA1)
AJM: 119049860(IL13RA1)
MMF: 118635677(IL13RA1)
PALE: 102897874(IL13RA1)
PGIG: 120586052(IL13RA1)
RAY: 107499873(IL13RA1)
MJV: 108386976 108394461(IL13RA1)
TOD: 119245536(IL13RA1)
LAV: 100661365(IL13RA1)
TMU: 101361875
MDO: 100022626(IL13RA1)
SHR: 100930920(IL13RA1)
PCW: 110192322(IL13RA1)
OAA: 100073895(IL13RA1)
GGA: 422230(IL13RA1)
PCOC: 116229454(IL13RA1)
MGP: 104912206(IL13RA1)
CJO: 107312740(IL13RA1)
NMEL: 110403298(IL13RA1)
APLA: 101790036(IL13RA1)
ACYG: 106037467(IL13RA1)
TGU: 105759145(IL13RA1)
LSR: 110480461(IL13RA1)
SCAN: 103816543(IL13RA1)
PMOA: 120506239(IL13RA1)
GFR: 102036927(IL13RA1)
FAB: 101811329(IL13RA1)
PHI: 102109254(IL13RA1)
PMAJ: 107203811(IL13RA1)
CCAE: 111928746(IL13RA1)
CCW: 104694412(IL13RA1)
ETL: 114065225(IL13RA1)
FPG: 101914743(IL13RA1)
FCH: 102048009(IL13RA1)
CLV: 102098333(IL13RA1)
EGZ: 104124277(IL13RA1)
NNI: 104012887(IL13RA1)
ACUN: 113480236(IL13RA1)
PADL: 103923359(IL13RA1)
AAM: 106490786(IL13RA1)
NPD: 112947087(IL13RA1)
ASN: 102385601(IL13RA1)
AMJ: 102567463(IL13RA1)
CPOO: 109310987(IL13RA1)
GGN: 109300332(IL13RA1)
PSS: 102455019(IL13RA1)
CMY: 102935958(IL13RA1)
CPIC: 101953818(IL13RA1)
TST: 117882855(IL13RA1)
CABI: 116822531(IL13RA1)
PVT: 110080190(IL13RA1)
PBI: 103062434(IL13RA1)
PMUR: 107303246(IL13RA1)
TSR: 106547215
PGUT: 117679597(IL13RA1)
PMUA: 114581758 114589039(IL13RA1)
ZVI: 118078248(IL13RA1) 118095792
GJA: 107114687(IL13RA1)
XTR: 101732462(il13ra1)
NPR: 108789061(IL13RA1)
DRE: 799475(il13ra1)
IPU: 108268101
TRU: 101077559
NCC: 104947892
SLUC: 116042364
XMA: 111611091
PRET: 103480167
CVG: 107099657
KMR: 108250046
ALIM: 106527932
LCF: 108882024
HCQ: 109515089
OMY: 100653446(il13ra1a) 100653447(il13ra1b) 110500556(il13ra1) 110500589
SFM: 108929722
AANG: 118222135(il13ra1)
LOC: 107077872
PSPA: 121318626
ARUT: 117412028
LCM: 102352466
CMK: 103177219 103177953(il13ra1)
RTP: 109938188
LDC: 111513166
 » show all
Reference
PMID:9130652
  Authors
Gauchat JF, Schlagenhauf E, Feng NP, Moser R, Yamage M, Jeannin P, Alouani S, Elson G, Notarangelo LD, Wells T, Eugster HP, Bonnefoy JY
  Title
A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor.
  Journal
Eur J Immunol 27:971-8 (1997)
DOI:10.1002/eji.1830270425
  Sequence
[hsa:3597]
Reference
  Authors
Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K
  Title
Characterization of the interaction between interleukin-13 and interleukin-13 receptors.
  Journal
J Biol Chem 280:24915-22 (2005)
DOI:10.1074/jbc.M502571200
LinkDB

KEGG   ORTHOLOGY: K05077
Entry
K05077                      KO                                     

Symbol
IL13RA2, CD213A2
Name
interleukin 13 receptor alpha-2
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
   04090 CD molecules
    K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K05077  IL13RA2, CD213A2; interleukin 13 receptor alpha-2
CD molecules [BR:ko04090]
 Proteins
  K05077  CD213a2, IL13RA2; interleukin 13 receptor, alpha 2
Genes
HSA: 3598(IL13RA2)
PTR: 107971205(IL13RA2)
PPS: 100986352(IL13RA2)
GGO: 101153265(IL13RA2)
PON: 100441311(IL13RA2)
NLE: 100601369(IL13RA2)
MCC: 708339(IL13RA2)
MCF: 102121264(IL13RA2)
CSAB: 103232516(IL13RA2)
CATY: 105598423(IL13RA2)
PANU: 101015260(IL13RA2)
RRO: 104657075(IL13RA2)
RBB: 108512758(IL13RA2)
TFN: 117077685(IL13RA2)
PTEH: 111536698(IL13RA2)
CJC: 100387833(IL13RA2)
SBQ: 101049403(IL13RA2)
MMUR: 105862918(IL13RA2)
MMU: 16165(Il13ra2)
MCAL: 110287251(Il13ra2)
MPAH: 110314118(Il13ra2)
RNO: 171060(Il13ra2)
MCOC: 116097084(Il13ra2)
MUN: 110540890(Il13ra2)
CGE: 100754617(Il13ra2)
PLEU: 114684059(Il13ra2)
NGI: 103740877(Il13ra2)
HGL: 101725943(Il13ra2)
CCAN: 109675255(Il13ra2)
OCU: 100348025(IL13RA2)
TUP: 102475625(IL13RA2)
CFA: 403622(IL13RA2)
VVP: 112908446(IL13RA2)
VLG: 121483113(IL13RA2)
AML: 100473482(IL13RA2)
UMR: 103679731(IL13RA2)
UAH: 113241251(IL13RA2)
ORO: 101363367(IL13RA2)
ELK: 111160969
MPUF: 101670921(IL13RA2)
EJU: 114201423(IL13RA2)
MLX: 118012175(IL13RA2)
FCA: 101100114(IL13RA2)
PYU: 121025709(IL13RA2)
PTG: 102965374(IL13RA2)
PPAD: 109253688(IL13RA2)
AJU: 106985372(IL13RA2)
HHV: 120247969(IL13RA2)
BTA: 616008(IL13RA2)
BOM: 102264417(IL13RA2)
BBUB: 102413125(IL13RA2)
CHX: 102173926(IL13RA2)
OAS: 101108025(IL13RA2)
ODA: 120881412(IL13RA2)
CCAD: 122434905(IL13RA2)
SSC: 100156991(IL13RA2)
CFR: 102522527(IL13RA2)
CBAI: 105070459(IL13RA2)
CDK: 105105362(IL13RA2)
BACU: 103009913(IL13RA2)
LVE: 103082651(IL13RA2)
OOR: 101287349(IL13RA2)
DLE: 111165769(IL13RA2)
PCAD: 102982035(IL13RA2)
ECB: 100057673(IL13RA2)
EPZ: 103542488(IL13RA2)
EAI: 106827332(IL13RA2)
MYB: 102258174(IL13RA2)
MYD: 102771151(IL13RA2)
MMYO: 118654634(IL13RA2)
MNA: 107537520(IL13RA2)
HAI: 109372367(IL13RA2)
DRO: 112308258(IL13RA2)
SHON: 118982604(IL13RA2)
AJM: 119034538(IL13RA2)
MMF: 118636188(IL13RA2)
PALE: 102889724(IL13RA2)
PGIG: 120615745(IL13RA2)
RAY: 107503633(IL13RA2)
MJV: 108399808(IL13RA2)
TOD: 119245953(IL13RA2)
LAV: 100663910(IL13RA2)
TMU: 101357132
MDO: 100010896(IL13RA2)
SHR: 100923207(IL13RA2)
PCW: 110192377(IL13RA2)
OAA: 103167024(IL13RA2)
GGA: 422219(IL13RA2)
PCOC: 116229611(IL13RA2)
MGP: 100545119
CJO: 107312634(IL13RA2)
NMEL: 110403169(IL13RA2)
APLA: 101792309(IL13RA2)
ACYG: 106037443(IL13RA2)
TGU: 100229083(IL13RA2)
LSR: 110479892(IL13RA2)
SCAN: 103816510(IL13RA2)
PMOA: 120506262(IL13RA2)
GFR: 102043061(IL13RA2)
FAB: 101815204(IL13RA2)
PHI: 102101177(IL13RA2)
PMAJ: 107203886(IL13RA2)
CCAE: 111929358(IL13RA2)
CCW: 104691664(IL13RA2)
ETL: 114067314(IL13RA2)
FPG: 101916000(IL13RA2)
FCH: 102049228(IL13RA2)
CLV: 102096119(IL13RA2)
EGZ: 104124261(IL13RA2)
NNI: 104012893(IL13RA2)
ACUN: 113479964(IL13RA2)
PADL: 103923353(IL13RA2)
AAM: 106489786(IL13RA2)
NPD: 112948657(IL13RA2)
ASN: 102382565(IL13RA2)
AMJ: 102571398(IL13RA2)
CPOO: 109310979(IL13RA2)
GGN: 109300572(IL13RA2)
CMY: 102941697(IL13RA2)
CPIC: 101950324(IL13RA2)
TST: 117882617(IL13RA2)
CABI: 116822524(IL13RA2)
XLA: 100049773(il13ra2.L) 495398(il13ra2.S)
XTR: 100496319(il13ra2)
NPR: 108787210
DRE: 368326(il13ra2)
IPU: 108260391(IL13RA2)
PHYP: 113531201
AMEX: 103023546
EEE: 113586806
TRU: 101077503
LCO: 104935298
NCC: 104962335
ELY: 117246476 117263395(il13ra2)
PLEP: 121952993(il13ra2) 121962394
SLUC: 116042287 116064998(il13ra2)
ECRA: 117934828 117955298(il13ra2)
GAT: 120822627(il13ra2) 120822644
MSAM: 119895930(il13ra2)
MZE: 101482752(il13ra2)
ONL: 100695034(il13ra2)
OAU: 116336179(il13ra2)
OML: 112143045(il13ra2) 112156453(il13ra1)
XMA: 102219136
XCO: 114153351
PRET: 103475830(il13ra1)
CVG: 107089837
CTUL: 119772172(il13ra1) 119786064(il13ra2)
NFU: 107386447
KMR: 108245212(il13ra2)
AOCE: 111574273
CSEM: 103395558(il13ra2)
POV: 109628497
LCF: 108893477
SDU: 111234437
SLAL: 111666298
XGL: 120802967(il13ra2)
HCQ: 109517827
BPEC: 110158589
MALB: 109959560
OMY: 100135968 100653488(il13ra2b)
ELS: 105030443
LOC: 102695590(il13ra2)
PSPA: 121295217(il13ra2) 121318633
LCM: 102362095(IL13RA2) 102364596
CMK: 103177887(il13ra2)
 » show all
Reference
PMID:8663118
  Authors
Caput D, Laurent P, Kaghad M, Lelias JM, Lefort S, Vita N, Ferrara P
  Title
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain.
  Journal
J Biol Chem 271:16921-6 (1996)
DOI:10.1074/jbc.271.28.16921
  Sequence
[hsa:3598]
Reference
  Authors
Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K
  Title
Characterization of the interaction between interleukin-13 and interleukin-13 receptors.
  Journal
J Biol Chem 280:24915-22 (2005)
DOI:10.1074/jbc.M502571200
LinkDB

KEGG   ORTHOLOGY: K05074
Entry
K05074                      KO                                     

Symbol
IL15RA, CD215
Name
interleukin 15 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04672  Intestinal immune network for IgA production
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
   04090 CD molecules
    K05074  IL15RA, CD215; interleukin 15 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05074  IL15RA, CD215; interleukin 15 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05074  CD215, IL15RA; interleukin 15 receptor, alpha
Genes
HSA: 3601(IL15RA)
PTR: 738192(IL15RA)
PPS: 100994584(IL15RA)
GGO: 101125849(IL15RA)
PON: 100439247(IL15RA)
NLE: 100603939(IL15RA)
MCC: 712788(IL15RA)
MCF: 102121571(IL15RA)
CSAB: 103237835(IL15RA)
CATY: 105597479(IL15RA)
PANU: 101003876(IL15RA)
RRO: 104664843(IL15RA)
RBB: 108529905(IL15RA)
TFN: 117082582(IL15RA)
PTEH: 111554867(IL15RA)
CJC: 100413804(IL15RA)
SBQ: 101036913(IL15RA)
MMUR: 105858206(IL15RA)
MMU: 16169(Il15ra)
MCAL: 110312676(Il15ra)
MPAH: 110333882(Il15ra)
RNO: 690369(Il15ra)
MCOC: 116082267(Il15ra)
MUN: 110556898(Il15ra)
CGE: 100755321(Il15ra)
PLEU: 114708198(Il15ra)
NGI: 103727307(Il15ra) 108490034
HGL: 101721276(Il15ra)
CCAN: 109690613(Il15ra)
OCU: 100358749 100359262(IL15RA)
TUP: 102468168(IL15RA)
CFA: 487141(IL15RA)
VVP: 112907422(IL15RA)
VLG: 121496899(IL15RA)
AML: 105238122(IL15RA)
UMR: 103676282(IL15RA)
UAH: 113241139(IL15RA)
ORO: 101378787(IL15RA)
ELK: 111158614
MPUF: 101675831(IL15RA)
EJU: 114217691(IL15RA)
MLX: 118021613(IL15RA)
FCA: 101082243(IL15RA)
PYU: 121014607(IL15RA)
PTG: 102970696(IL15RA)
PPAD: 109273770(IL15RA)
AJU: 106982336(IL15RA)
HHV: 120237184(IL15RA)
BTA: 615030(IL15RA)
BOM: 102276746(IL15RA)
BIU: 109567895(IL15RA)
BBUB: 102407360(IL15RA)
CHX: 102171722(IL15RA)
OAS: 101107377(IL15RA)
ODA: 120869149(IL15RA)
CCAD: 122448518(IL15RA)
SSC: 733692(IL15RA)
CFR: 102520156(IL15RA)
CBAI: 105074341(IL15RA)
CDK: 105091356(IL15RA)
BACU: 103010610(IL15RA)
LVE: 103073718(IL15RA)
OOR: 101283027(IL15RA)
DLE: 111177976(IL15RA)
PCAD: 102984980(IL15RA)
ECB: 100070311(IL15RA)
EPZ: 103548904(IL15RA)
EAI: 106833793(IL15RA)
MYB: 102250121(IL15RA)
MYD: 102769926(IL15RA)
MMYO: 118672325(IL15RA)
MNA: 107542422(IL15RA)
HAI: 109383808(IL15RA)
DRO: 112321252(IL15RA)
SHON: 119000806(IL15RA)
AJM: 119048019(IL15RA)
MMF: 118617636(IL15RA)
PALE: 102892156(IL15RA)
PGIG: 120609702(IL15RA)
RAY: 107501633(IL15RA)
MJV: 108407553(IL15RA)
TOD: 119244169(IL15RA)
LAV: 100655923(IL15RA)
TMU: 101342850
MDO: 103092906(IL15RA)
SHR: 105750697(IL15RA)
PCW: 110198995(IL15RA)
OAA: 100085842(IL15RA)
GGA: 416686(IL15RA)
PCOC: 116236460(IL15RA)
MGP: 104910273(IL15RA)
CJO: 107311644(IL15RA)
NMEL: 110392215
ACYG: 106038761(IL15RA)
TGU: 115498116(IL15RA)
LSR: 110478883(IL15RA)
SCAN: 103822505(IL15RA)
PMOA: 120502564(IL15RA)
FAB: 107604190(IL15RA)
CCAE: 111923220(IL15RA)
FPG: 106112379
FCH: 106630898(IL15RA)
CLV: 102088251(IL15RA)
EGZ: 104134805(IL15RA)
NNI: 104010514(IL15RA)
PADL: 103922822(IL15RA)
ASN: 102371084(IL15RA)
AMJ: 102565439(IL15RA)
CPOO: 109316017(IL15RA)
GGN: 109292270(IL15RA)
PSS: 112545330(IL15RA)
CMY: 114018524(IL15RA)
CPIC: 101940857(IL15RA)
TST: 117874163(IL15RA)
CABI: 116835047(IL15RA)
ACS: 103278806(il15ra)
PVT: 110070598(IL15RA)
PMUA: 114604839
ZVI: 118091031
XTR: 101732951(il15ra)
SRX: 107755151(il15ra)
SGH: 107567656 107597019(il15ra)
IPU: 108279850
PHYP: 113532074
EEE: 113584017
TRU: 100190944(il15ra)
LCO: 104933240(il15ra)
NCC: 104955337
CGOB: 115028379
ELY: 117248991(il15ra)
PLEP: 121961250(il15ra)
SLUC: 116054527(il15ra)
ECRA: 117938648(il15ra)
PFLV: 114550354(il15ra)
GAT: 100190876(il-15ra)
MSAM: 119918544(il15ra)
CUD: 121505362(il15ra)
MZE: 105941328(il15ra)
ONL: 100696399 100696663(il15ra)
OAU: 116330943(il15ra) 120434067
OLA: 101163373(il15ra)
OML: 112138290(il15ra)
XMA: 102232595(il15ra) 111609416
XCO: 114149248 114161061(il15ra)
XHE: 116725039 116736818(il15ra)
PRET: 103459672(il15ra) 103473251
CVG: 107096225(il15ra)
CTUL: 119784756 119794461(il15ra)
NFU: 107382639
KMR: 108245560(il15ra)
ALIM: 106524596(il15ra)
AOCE: 111579124(il15ra)
CSEM: 103383115
POV: 109632773(il15ra)
LCF: 108874267(il15ra)
SDU: 111224828(il15ra)
SLAL: 111667321(il15ra)
XGL: 120801866(il15ra)
HCQ: 109528860
BPEC: 110161835(il15ra)
MALB: 109960894
SASA: 106576191 106609274(il15ra)
OMY: 110490348
SALP: 111949768(il15ra) 111951524
SNH: 120049407(il15ra)
ELS: 106024893(il15ra)
PSPA: 121318249(il15ra) 121319865
ARUT: 117415182(il15ra) 117420067
CMK: 103176943(il15ra)
 » show all
Reference
PMID:8530383
  Authors
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA, et al.
  Title
Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.
  Journal
J Biol Chem 270:29862-9 (1995)
DOI:10.1074/jbc.270.50.29862
  Sequence
[hsa:3601]
LinkDB

KEGG   ORTHOLOGY: K05136
Entry
K05136                      KO                                     

Symbol
IL20RA
Name
interleukin 20 receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05136  IL20RA; interleukin 20 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05136  IL20RA; interleukin 20 receptor alpha
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05136  IL20RA; interleukin 20 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05136  IL20RA; interleukin 20 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05136  IL20RA; interleukin 20 receptor alpha
Genes
HSA: 53832(IL20RA)
PTR: 463026(IL20RA)
PPS: 100993433(IL20RA)
GGO: 101145811(IL20RA)
PON: 100455762(IL20RA)
NLE: 100597478(IL20RA)
MCC: 704890(IL20RA)
MCF: 102141570(IL20RA)
CSAB: 103240305(IL20RA)
CATY: 105600396(IL20RA)
PANU: 101001402(IL20RA)
RRO: 104675018(IL20RA)
RBB: 108522971(IL20RA)
TFN: 117097475(IL20RA)
PTEH: 111525545(IL20RA)
CJC: 100392660(IL20RA)
SBQ: 101053121(IL20RA)
MMUR: 105857218 109730807(IL20RA)
MMU: 237313(Il20ra)
MCAL: 110303777(Il20ra)
MPAH: 110338370(Il20ra)
RNO: 308716(Il20ra)
MCOC: 116097809(Il20ra)
MUN: 110539321(Il20ra)
CGE: 100751800(Il20ra)
PLEU: 114686994(Il20ra)
NGI: 103724898(Il20ra)
HGL: 101699117(Il20ra)
CCAN: 109697038(Il20ra)
OCU: 100341271(IL20RA)
TUP: 102474468(IL20RA)
CFA: 484002(IL20RA)
VVP: 112919470(IL20RA)
VLG: 121480778(IL20RA)
AML: 100476037(IL20RA)
UMR: 103663373(IL20RA)
UAH: 113259484(IL20RA)
ORO: 101383227(IL20RA)
MPUF: 101690773(IL20RA)
EJU: 114222798(IL20RA)
MLX: 118000836(IL20RA)
FCA: 101086565(IL20RA)
PYU: 121013408(IL20RA)
PTG: 102953488(IL20RA)
PPAD: 109249876(IL20RA)
AJU: 106983677(IL20RA)
HHV: 120239355(IL20RA)
BTA: 509038(IL20RA)
BOM: 102275814(IL20RA)
BIU: 109563983(IL20RA)
BBUB: 102409466(IL20RA)
CHX: 102182229(IL20RA)
OAS: 101112653(IL20RA)
ODA: 120863073(IL20RA)
CCAD: 122434006(IL20RA)
SSC: 100622457(IL20RA)
CFR: 102522495(IL20RA)
CBAI: 105077266(IL20RA)
CDK: 105092039(IL20RA)
BACU: 103000232(IL20RA)
LVE: 103082390(IL20RA)
OOR: 101276303(IL20RA)
DLE: 111166190(IL20RA)
PCAD: 102976328(IL20RA)
ECB: 100073190(IL20RA)
EPZ: 103549042(IL20RA)
EAI: 106837195(IL20RA)
MYB: 102257555(IL20RA)
MYD: 102761844(IL20RA)
MMYO: 118659705(IL20RA)
MNA: 107530947(IL20RA)
HAI: 109385626(IL20RA)
DRO: 112297383(IL20RA)
SHON: 118986671(IL20RA)
AJM: 119051856(IL20RA)
MMF: 118621756(IL20RA)
PALE: 102888258(IL20RA)
PGIG: 120615775(IL20RA)
RAY: 107521300(IL20RA)
MJV: 108410302(IL20RA)
TOD: 119252909(IL20RA)
LAV: 100666028(IL20RA) 100669996
TMU: 101345836
MDO: 100031550(IL20RA)
SHR: 100919001(IL20RA)
PCW: 110208926(IL20RA)
OAA: 100078655(IL20RA)
GGA: 421686(IL20RA)
PCOC: 116240599(IL20RA)
MGP: 100550945(IL20RA)
CJO: 107311681(IL20RA)
NMEL: 110396760(IL20RA)
APLA: 101799672(IL20RA)
ACYG: 106032517(IL20RA)
TGU: 100228054(IL20RA)
LSR: 116183471(IL20RA)
SCAN: 103818467(IL20RA)
PMOA: 120501304(IL20RA)
GFR: 102040710(IL20RA)
FAB: 101813408(IL20RA)
PHI: 102103535(IL20RA)
PMAJ: 107202610(IL20RA)
CCAE: 111926797(IL20RA)
CCW: 104689465(IL20RA)
ETL: 114059506(IL20RA)
FPG: 101910732(IL20RA)
FCH: 102056524(IL20RA)
CLV: 102096992(IL20RA)
EGZ: 104131194(IL20RA)
NNI: 104008815(IL20RA)
ACUN: 113478327(IL20RA)
PADL: 103912707(IL20RA)
AAM: 106497921(IL20RA)
NPD: 112954936(IL20RA)
ASN: 102373917(IL20RA) 112549711
AMJ: 102561778(IL20RA)
CPOO: 109320190(IL20RA)
GGN: 109304834(IL20RA)
PSS: 102448764(IL20RA)
CMY: 102941168(IL20RA)
CPIC: 101934716(IL20RA)
TST: 117874899(IL20RA)
CABI: 116818809(IL20RA)
PBI: 112540929
TSR: 106551923
PGUT: 117666300(IL20RA)
PMUA: 114593403
ZVI: 118082068(IL20RA)
GJA: 107121391
XLA: 108717882
XTR: 100496393
DRE: 556728(il20ra)
IPU: 108257712
PHYP: 113536961
AMEX: 103025249
EEE: 113590743
TRU: 101067572
LCO: 104927387
CGOB: 115003921
ELY: 117266190(ifnlr1) 117270609
PLEP: 121945914(ifnlr1) 121955598(il20ra)
SLUC: 116060801(ifnlr1) 116066129(il20ra)
ECRA: 117946761(ifnlr1) 117961666(il20ra)
PFLV: 114573255
GAT: 120807972(il20ra) 120810002(ifnlr1)
MSAM: 119897253(ifnlr1) 119909155(il20ra)
CUD: 121514168 121521081(il20ra)
MZE: 101482649
ONL: 102078941
OAU: 116320972(ifnlr1) 116332274(il20ra)
OML: 112143911(ifnlr1) 112157899(il20ra)
CTUL: 119777463(ifnlr1) 119788701(il20ra)
KMR: 108231739(il20ra)
AOCE: 111578307
CSEM: 103380797
SLAL: 111672783
XGL: 120784508(ifnlr1) 120788677(il20ra)
HCQ: 109509473
BPEC: 110155246
MALB: 109962234
SASA: 106571364 106607764(I20RA)
OMY: 100136639(il20ra) 101268947
ELS: 105017922
SFM: 108928446(il20ra)
AANG: 118221934 118229064(il20ra)
LCM: 102347862
CMK: 103178321(il20ra)
RTP: 109922743
BBEL: 109477896
 » show all
Reference
  Authors
Kingo K, Mossner R, Ratsep R, Raud K, Kruger U, Silm H, Vasar E, Reich K, Koks S
  Title
Association analysis of IL20RA and IL20RB genes in psoriasis.
  Journal
Genes Immun 9:445-51 (2008)
DOI:10.1038/gene.2008.36
  Sequence
[hsa:53832]
LinkDB

KEGG   ORTHOLOGY: K05137
Entry
K05137                      KO                                     

Symbol
IL20RB
Name
interleukin 20 receptor beta
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05137  IL20RB; interleukin 20 receptor beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05137  IL20RB; interleukin 20 receptor beta
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05137  IL20RB; interleukin 20 receptor beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05137  IL20RB; interleukin 20 receptor beta
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05137  IL20RB; interleukin 20 receptor beta
Genes
HSA: 53833(IL20RB)
PTR: 742595(IL20RB)
PPS: 100977044(IL20RB)
GGO: 101140860(IL20RB)
PON: 100458031(IL20RB)
NLE: 100605549(IL20RB)
MCC: 716769(IL20RB)
MCF: 102119675(IL20RB)
CSAB: 103241621(IL20RB)
CATY: 105586401(IL20RB)
PANU: 101016009(IL20RB)
RRO: 104663558(IL20RB)
RBB: 108531426(IL20RB)
TFN: 117084143(IL20RB)
PTEH: 111523346(IL20RB)
CJC: 100394922(IL20RB)
SBQ: 101048007(IL20RB)
MMUR: 105884057(IL20RB)
MMU: 213208(Il20rb)
MCAL: 110302285(Il20rb)
MPAH: 110328622(Il20rb)
RNO: 501043(Il20rb)
MCOC: 116072998(Il20rb)
MUN: 110555020(Il20rb)
CGE: 100772546(Il20rb)
PLEU: 114693550(Il20rb)
NGI: 103740975(Il20rb)
HGL: 101721740(Il20rb)
CCAN: 109700188(Il20rb)
OCU: 100349338(IL20RB)
TUP: 102470050(IL20RB)
CFA: 610961(IL20RB)
VVP: 112932561(IL20RB)
VLG: 121478883(IL20RB)
AML: 100472789(IL20RB)
UMR: 103678770(IL20RB)
UAH: 113253976(IL20RB)
ORO: 101362999(IL20RB)
ELK: 111155008
MPUF: 101691168(IL20RB)
EJU: 114205714(IL20RB)
MLX: 118004199(IL20RB)
FCA: 101081159(IL20RB)
PYU: 121033716(IL20RB)
PTG: 102967514(IL20RB)
PPAD: 109259707(IL20RB)
HHV: 120224467(IL20RB)
BTA: 534581(IL20RB)
BOM: 102279525(IL20RB)
BIU: 109560001(IL20RB)
BBUB: 102414637(IL20RB)
CHX: 102189714(IL20RB)
OAS: 101113034(IL20RB)
ODA: 120857605(IL20RB)
CCAD: 122445292(IL20RB)
SSC: 100620875(IL20RB)
CFR: 102520651(IL20RB)
CBAI: 105063238(IL20RB)
CDK: 105085276(IL20RB)
BACU: 103020362(IL20RB)
LVE: 103069282(IL20RB)
OOR: 101278501(IL20RB)
DLE: 111179218(IL20RB)
PCAD: 102981533(IL20RB)
ECB: 100066346(IL20RB)
EPZ: 103540014(IL20RB)
EAI: 106838087(IL20RB)
MYB: 102238858(IL20RB)
MYD: 102755451(IL20RB)
MMYO: 118668138(IL20RB)
MNA: 107546079(IL20RB)
HAI: 109389241(IL20RB)
DRO: 112309986(IL20RB)
SHON: 118997538(IL20RB)
AJM: 119044773(IL20RB)
MMF: 118633348(IL20RB)
PALE: 102882035(IL20RB)
PGIG: 120582119(IL20RB)
RAY: 107513947(IL20RB)
MJV: 108393777(IL20RB)
TOD: 119258212(IL20RB)
LAV: 100661481(IL20RB)
TMU: 101355538
MDO: 100024106(IL20RB)
SHR: 100925684(IL20RB)
PCW: 110208253(IL20RB)
OAA: 100085840(IL20RB)
GGA: 768437(IL20RB)
PCOC: 116230213(IL20RB)
MGP: 100551227(IL20RB)
CJO: 107320879(IL20RB)
NMEL: 110405960(IL20RB)
APLA: 101797018(IL20RB)
ACYG: 106033427(IL20RB)
TGU: 100220626(IL20RB)
SCAN: 103817740(IL20RB)
PMOA: 120512865(IL20RB)
GFR: 102035348
FAB: 101806898(IL20RB)
PHI: 102110642(IL20RB)
PMAJ: 107211029(IL20RB)
CCAE: 111935914
CCW: 104684693(IL20RB)
ETL: 114057044(IL20RB)
FPG: 101911016(IL20RB)
FCH: 102053457(IL20RB)
CLV: 102089199(IL20RB)
EGZ: 104135749(IL20RB)
NNI: 104023436(IL20RB)
ACUN: 113485726(IL20RB)
PADL: 103917617(IL20RB)
AAM: 106482415(IL20RB)
NPD: 112955609(IL20RB)
ASN: 102384456(IL20RB)
AMJ: 102569524(IL20RB)
PSS: 102454548(IL20RB)
CMY: 102947072(IL20RB)
CPIC: 101943147(IL20RB)
TST: 117884276(IL20RB)
CABI: 116833263(IL20RB)
ACS: 100553073(il20rb)
PVT: 110089675
PBI: 103048387(IL20RB)
PMUR: 107288033(IL20RB)
TSR: 106550781
PGUT: 117669305(IL20RB)
PMUA: 114603208(IL20RB)
ZVI: 118086933(IL20RB)
GJA: 107122019(IL20RB)
XTR: 101734011(il20rb)
DRE: 100174902(crfb16)
SRX: 107758261
SANH: 107676306
SGH: 107568418
CCAR: 109085662
CAUA: 113114976
IPU: 108280709
PHYP: 113546424
AMEX: 103026887(il20rb)
EEE: 113590148(il20rb)
TRU: 105418284
LCO: 104937176(il20rb)
NCC: 104949632
CGOB: 115022276(il20rb)
ELY: 117271696(crfb16)
PLEP: 121951747(crfb16)
SLUC: 116045190(crfb16)
ECRA: 117954641(crfb16)
GAT: 120816644(crfb16)
MSAM: 119902635(crfb16)
CUD: 121519873(crfb16)
MZE: 106675576
ONL: 102078285
OAU: 116327964(crfb16)
OLA: 111949120
XMA: 106700083
XCO: 114146341
PRET: 103460591(il20rb)
CTUL: 119773112(crfb16) 119777365
NFU: 107383732
KMR: 108229498(crfb16)
AOCE: 111586558
CSEM: 103396856
POV: 109644762
LCF: 108882456(il20rb)
SDU: 111233287
SLAL: 111646412(il20rb)
HCQ: 109518842
BPEC: 110166057(il20rb)
MALB: 109970251
SASA: 106568648
OTW: 112261063
OMY: 110529952(crfb16)
SALP: 111956288
ELS: 105023297
PKI: 111836667(il20rb)
AANG: 118229463(crfb16)
LOC: 107079194
PSPA: 121323069(crfb16)
ARUT: 117423101(crfb16)
CMK: 103188725(il20rb)
 » show all
Reference
  Authors
Kingo K, Mossner R, Ratsep R, Raud K, Kruger U, Silm H, Vasar E, Reich K, Koks S
  Title
Association analysis of IL20RA and IL20RB genes in psoriasis.
  Journal
Genes Immun 9:445-51 (2008)
DOI:10.1038/gene.2008.36
  Sequence
[hsa:53833]
LinkDB

KEGG   ORTHOLOGY: K05075
Entry
K05075                      KO                                     

Symbol
IL21R, CD360
Name
interleukin 21 receptor
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04659  Th17 cell differentiation
map05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05075  IL21R, CD360; interleukin 21 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05075  IL21R, CD360; interleukin 21 receptor
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K05075  IL21R, CD360; interleukin 21 receptor
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05075  IL21R, CD360; interleukin 21 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05075  IL21R, CD360; interleukin 21 receptor
   04090 CD molecules
    K05075  IL21R, CD360; interleukin 21 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05075  IL21R, CD360; interleukin 21 receptor
CD molecules [BR:ko04090]
 Proteins
  K05075  CD360, IL21R; interleukin 21 receptor
Genes
HSA: 50615(IL21R)
PTR: 454006(IL21R)
PPS: 100970355(IL21R)
GGO: 101129403(IL21R)
PON: 100450175(IL21R)
NLE: 100601027(IL21R)
MCC: 705759(IL21R)
MCF: 102135042(IL21R)
CSAB: 103230109(IL21R)
CATY: 105598474(IL21R)
PANU: 101023386(IL21R)
RRO: 104670204(IL21R)
RBB: 108518245(IL21R)
PTEH: 111529206(IL21R)
CJC: 100401171(IL21R)
SBQ: 101045058(IL21R)
MMUR: 105879690
MMU: 60504(Il21r)
MCAL: 110298844(Il21r)
MPAH: 110331013(Il21r)
RNO: 308977(Il21r)
MCOC: 116102935(Il21r)
MUN: 110564645(Il21r)
CGE: 100763133(Il21r)
PLEU: 114692225(Il21r)
NGI: 103741072(Il21r)
HGL: 101701307(Il21r)
CCAN: 109698035(Il21r)
OCU: 103348594(IL21R)
TUP: 102469112(IL21R)
CFA: 608011(IL21R)
VVP: 112929180(IL21R)
VLG: 121487720(IL21R)
AML: 100467688(IL21R)
UMR: 103657903(IL21R)
UAH: 113267611(IL21R)
ORO: 101382783(IL21R)
ELK: 111162173
MPUF: 101681500(IL21R)
EJU: 114214376(IL21R)
MLX: 117999672(IL21R)
FCA: 101096026(IL21R)
PYU: 121022464(IL21R)
PTG: 102949594(IL21R)
PPAD: 109256534(IL21R)
AJU: 106966181(IL21R)
HHV: 120249043(IL21R)
BTA: 617967(IL21R)
BOM: 102274052(IL21R)
BIU: 109578841(IL21R)
BBUB: 102393447(IL21R)
CHX: 102176844(IL21R)
OAS: 100820753(IL21R)
ODA: 120876446(IL21R)
CCAD: 122433433(IL21R)
SSC: 100518723(IL21R)
CFR: 102505205(IL21R)
CBAI: 105073656(IL21R)
CDK: 105098255(IL21R)
BACU: 103018703(IL21R)
LVE: 103085231(IL21R)
OOR: 101281486(IL21R)
DLE: 111182214(IL21R)
PCAD: 102985030(IL21R)
ECB: 100066814(IL21R)
EPZ: 103556346(IL21R)
EAI: 106829084(IL21R)
MYB: 102263626(IL21R)
MYD: 102762032(IL21R)
MMYO: 118652925(IL21R)
MNA: 107539652(IL21R)
HAI: 109385808(IL21R)
DRO: 112304897(IL21R)
AJM: 119045347(IL21R)
MMF: 118641932(IL21R)
PALE: 102883062(IL21R)
PGIG: 120620493(IL21R)
RAY: 107506152(IL21R)
MJV: 108405151(IL21R)
TOD: 119242350(IL21R)
LAV: 100655109(IL21R)
TMU: 101355640
MDO: 100016040(IL21R)
SHR: 100920794(IL21R)
PCW: 110221598(IL21R)
OAA: 100079376(IL21R)
GGA: 416586(IL21R)
PCOC: 116237420(IL21R)
MGP: 100547386(IL21R)
CJO: 107320804(IL21R)
NMEL: 110405597(IL21R)
APLA: 101796991(IL21R)
ACYG: 106046044(IL21R)
TGU: 100230851(IL21R)
LSR: 110477759(IL21R)
SCAN: 103817551(IL21R)
PMOA: 120513204(IL21R)
GFR: 102032622(IL21R)
FAB: 101812777(IL21R)
PHI: 102107481(IL21R)
PMAJ: 107211180(IL21R)
CCAE: 111936217(IL21R)
CCW: 104684905(IL21R)
ETL: 114061436(IL21R)
FPG: 101913915(IL21R)
FCH: 102059759(IL21R)
CLV: 102087878(IL21R)
EGZ: 104131302(IL21R)
NNI: 104015159(IL21R)
ACUN: 113485936(IL21R)
PADL: 103913921(IL21R)
AAM: 106486130(IL21R)
NPD: 112959772(IL21R)
ASN: 102385153(IL21R)
AMJ: 102563981(IL21R)
CPOO: 109314586(IL21R)
GGN: 109294443(IL21R)
PSS: 102460432(IL21R)
CMY: 102946561(IL21R)
CPIC: 101943915(IL21R)
TST: 117883821(IL21R)
CABI: 116830028(IL21R)
ACS: 103281084(il21r)
PBI: 103064799(IL21R)
PMUR: 107302632(IL21R)
TSR: 106545984(IL21R)
PGUT: 117667341(IL21R)
PMUA: 114584164(IL21R)
ZVI: 118093300(IL21R)
GJA: 107106230(IL21R)
XLA: 108701892(il21r.L) 108702308(il21r.S)
XTR: 100492452(il21r)
NPR: 108794714(IL21R)
DRE: 100134976(il21r.1)
IPU: 108257365 108257366(il21r)
PHYP: 113535970(il21r)
AMEX: 103026064(il21r)
EEE: 113567475(il21r)
ELY: 117247447 117266455(il21r.1)
PLEP: 121946330(il21r.1) 121958801
SLUC: 116036123(il21r.1) 116044283
ECRA: 117937189 117946767(il21r.1)
MSAM: 119897116(il21r.1) 119915539
OAU: 116315408(il21r.1) 116319862
CTUL: 119780945(il21r.1) 119793811
KMR: 108237210 108248883(il21r.1)
ALIM: 106532258
XGL: 120783737
BPEC: 110168972
ELS: 105013397(il21r) 105021300
LOC: 102691298(il21r) 107078987
LCM: 102350329
CMK: 103186639(il21r)
RTP: 109922225
 » show all
Reference
  Authors
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D
  Title
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
  Journal
Nature 408:57-63 (2000)
DOI:10.1038/35040504
  Sequence
[hsa:50615]
Reference
  Authors
Leonard WJ, Zeng R, Spolski R
  Title
Interleukin 21: a cytokine/cytokine receptor system that has come of age.
  Journal
J Leukoc Biol 84:348-56 (2008)
DOI:10.1189/jlb.0308149
LinkDB

KEGG   ORTHOLOGY: K05138
Entry
K05138                      KO                                     

Symbol
IL22RA1
Name
interleukin 22 receptor alpha 1
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05138  IL22RA1; interleukin 22 receptor alpha 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05138  IL22RA1; interleukin 22 receptor alpha 1
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05138  IL22RA1; interleukin 22 receptor alpha 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05138  IL22RA1; interleukin 22 receptor alpha 1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05138  IL22RA1; interleukin 22 receptor alpha 1
Genes
HSA: 58985(IL22RA1)
PTR: 469224(IL22RA1)
PPS: 100989661(IL22RA1)
GGO: 101129829(IL22RA1)
PON: 100454377(IL22RA1)
NLE: 100588189(IL22RA1)
MCC: 719264(IL22RA1)
MCF: 102117911(IL22RA1)
CSAB: 103225378(IL22RA1)
CATY: 105594983(IL22RA1)
PANU: 101021910(IL22RA1)
RRO: 104656114(IL22RA1)
RBB: 108538464(IL22RA1)
TFN: 117093119(IL22RA1)
PTEH: 111547554(IL22RA1)
CJC: 100394149(IL22RA1)
SBQ: 101035704(IL22RA1)
MMUR: 105863576(IL22RA1)
MMU: 230828(Il22ra1)
MCAL: 110292616(Il22ra1)
MPAH: 110323524(Il22ra1)
RNO: 362629(Il22ra1)
MCOC: 116096845(Il22ra1)
MUN: 110545421(Il22ra1)
CGE: 100756546(Il22ra1)
PLEU: 114697151(Il22ra1)
NGI: 103746427(Il22ra1)
HGL: 101721365(Il22ra1)
CCAN: 109678631(Il22ra1)
OCU: 100344077(IL22RA1)
TUP: 102494145(IL22RA1)
CFA: 612279(IL22RA1)
VVP: 112930201(IL22RA1)
VLG: 121498217(IL22RA1)
AML: 100478388(IL22RA1)
UMR: 103666549(IL22RA1)
UAH: 113268505(IL22RA1)
ORO: 101363475(IL22RA1)
ELK: 111154911
MPUF: 101671675(IL22RA1)
EJU: 114217222(IL22RA1)
MLX: 118019877(IL22RA1)
FCA: 101100741(IL22RA1)
PYU: 121023186(IL22RA1)
PTG: 102962237(IL22RA1)
PPAD: 109274313(IL22RA1)
AJU: 106977588(IL22RA1)
HHV: 120230771(IL22RA1)
BTA: 508044(IL22RA1)
BOM: 102284614(IL22RA1)
BIU: 109577127(IL22RA1)
BBUB: 102401396(IL22RA1)
CHX: 102178497(IL22RA1)
OAS: 101118168(IL22RA1)
ODA: 120855097(IL22RA1)
CCAD: 122426768(IL22RA1)
SSC: 100623299(IL22RA1)
CFR: 102518591(IL22RA1)
CBAI: 105070843(IL22RA1)
CDK: 105097281(IL22RA1)
BACU: 102998136(IL22RA1)
LVE: 103076727(IL22RA1)
OOR: 101288886(IL22RA1)
DLE: 111163429(IL22RA1)
PCAD: 102977028(IL22RA1)
ECB: 100071510(IL22RA1)
EAI: 106839966(IL22RA1)
MYB: 102248850(IL22RA1)
MYD: 102769380(IL22RA1)
MMYO: 118677223(IL22RA1)
MNA: 107542211(IL22RA1)
HAI: 109386692(IL22RA1)
DRO: 112299002(IL22RA1)
SHON: 118977743(IL22RA1)
AJM: 119042227(IL22RA1)
MMF: 118627259(IL22RA1)
PALE: 102879965(IL22RA1)
PGIG: 120596037(IL22RA1)
RAY: 107501028(IL22RA1)
MJV: 108387774(IL22RA1)
TOD: 119237147(IL22RA1)
LAV: 100669119(IL22RA1)
TMU: 101353815
MDO: 100011239(IL22RA1)
SHR: 100913243(IL22RA1)
PCW: 110206073(IL22RA1)
OAA: 100077806(IL22RA1)
PCOC: 116230160(IL22RA1)
MGP: 100541684(IL22RA1)
CJO: 107323879(IL22RA1)
NMEL: 110387298(IL22RA1)
ACYG: 106037933(IL22RA1)
TGU: 115498274(IL22RA1)
LSR: 110472917(IL22RA1)
SCAN: 103823566(IL22RA1)
PMOA: 120513902(IL22RA1)
GFR: 102036896(IL22RA1)
FAB: 101818014(IL22RA1)
PHI: 102111901(IL22RA1)
CCAE: 111939114(IL22RA1)
ETL: 114067753(IL22RA1)
FPG: 101923569(IL22RA1)
FCH: 102055349(IL22RA1)
CLV: 102097786(IL22RA1)
EGZ: 104134963(IL22RA1)
NNI: 104017856(IL22RA1)
ACUN: 113488268(IL22RA1)
PADL: 103923762(IL22RA1)
AAM: 106493315(IL22RA1)
NPD: 112950880(IL22RA1)
ASN: 102384095(IL22RA1)
AMJ: 102573263(IL22RA1)
CPOO: 109318390(IL22RA1)
GGN: 109294133(IL22RA1)
PSS: 112546989(IL22RA1)
CMY: 114021328(IL22RA1)
TST: 117868386(IL22RA1)
CABI: 116830213(IL22RA1)
ACS: 103281918
PVT: 110082490(IL22RA1)
PBI: 103048905(IL22RA1)
PMUR: 107290758(IL22RA1)
TSR: 106542201
PGUT: 117663361(IL22RA1)
PMUA: 114601577(IL22RA1)
ZVI: 118087473(IL22RA1)
GJA: 107105581(IL22RA1) 107118516
XTR: 100497960(il22ra1)
NPR: 108800220
TRU: 101068298
CSEM: 103387924
HCQ: 109515440
SALP: 111959158
ELS: 105019309
SFM: 108919155
PKI: 111844546
PSPA: 121303453
LCM: 102356174(IL22RA1)
CMK: 103179443
RTP: 109910735
 » show all
Reference
  Authors
Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL
  Title
Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.
  Journal
J Biol Chem 275:31335-9 (2000)
DOI:10.1074/jbc.M005304200
  Sequence
[hsa:58985]
LinkDB

KEGG   ORTHOLOGY: K05139
Entry
K05139                      KO                                     

Symbol
IL22RA2
Name
interleukin 22 receptor alpha 2
Pathway
map04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05139  IL22RA2; interleukin 22 receptor alpha 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05139  IL22RA2; interleukin 22 receptor alpha 2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL10/28 receptor family
   K05139  IL22RA2; interleukin 22 receptor alpha 2
Genes
HSA: 116379(IL22RA2)
PTR: 472133(IL22RA2)
PPS: 100993771(IL22RA2)
GGO: 101146176(IL22RA2)
PON: 100456367(IL22RA2)
NLE: 100597809(IL22RA2)
MCC: 711059(IL22RA2)
MCF: 102143120(IL22RA2)
CSAB: 103240304(IL22RA2)
CATY: 105600395(IL22RA2)
PANU: 101001055(IL22RA2)
RRO: 104675020(IL22RA2)
RBB: 108522966(IL22RA2)
TFN: 117097474(IL22RA2)
PTEH: 111525554(IL22RA2)
CJC: 100386163(IL22RA2)
SBQ: 101027739(IL22RA2)
MMUR: 105860619(IL22RA2)
MMU: 237310(Il22ra2)
MCAL: 110303659(Il22ra2)
MPAH: 110338296(Il22ra2)
RNO: 444986(Il22ra2)
MCOC: 116097808(Il22ra2)
MUN: 110557644(Il22ra2)
CGE: 100751510(Il22ra2)
NGI: 103724897(Il22ra2)
HGL: 101698371(Il22ra2)
CCAN: 109697037(Il22ra2)
OCU: 100341531(IL22RA2)
TUP: 102475170(IL22RA2)
CFA: 100856046(IL22RA2)
VVP: 112919422(IL22RA2)
VLG: 121485399(IL22RA2)
AML: 100473512(IL22RA2)
UMR: 103663371(IL22RA2)
UAH: 113259362(IL22RA2)
ORO: 101375598(IL22RA2)
ELK: 111147765
MPUF: 101690202(IL22RA2)
EJU: 114222764(IL22RA2)
MLX: 118000837(IL22RA2)
FCA: 101083429(IL22RA2)
PYU: 121013405(IL22RA2)
PTG: 102952984(IL22RA2)
PPAD: 109249873(IL22RA2)
AJU: 106983676(IL22RA2)
HHV: 120239381(IL22RA2)
BTA: 533061(IL22RA2)
BOM: 102281719(IL22RA2)
BIU: 109563556(IL22RA2)
BBUB: 102409803(IL22RA2)
CHX: 102172720(IL22RA2)
OAS: 101121781(IL22RA2)
ODA: 120863074(IL22RA2)
CCAD: 122434088(IL22RA2)
SSC: 100513324(IL22RA2)
CFR: 102515188(IL22RA2)
CBAI: 105077435(IL22RA2)
CDK: 105092085(IL22RA2)
BACU: 103011409(IL22RA2)
LVE: 103083196(IL22RA2)
OOR: 101285394(IL22RA2)
DLE: 111168305(IL22RA2)
PCAD: 102979054(IL22RA2)
ECB: 100073194(IL22RA2)
EPZ: 103549044(IL22RA2)
EAI: 106837337(IL22RA2)
MYB: 102257763(IL22RA2)
MYD: 102770739(IL22RA2)
MMYO: 118659707(IL22RA2)
MNA: 107530946(IL22RA2)
HAI: 109385627(IL22RA2)
DRO: 112296917(IL22RA2)
SHON: 118986791(IL22RA2)
AJM: 119043834 119051866(IL22RA2)
MMF: 118621853(IL22RA2)
PALE: 102879846(IL22RA2)
PGIG: 120615776(IL22RA2)
RAY: 107521301(IL22RA2)
MJV: 108410305(IL22RA2)
TOD: 119251536(IL22RA2)
LAV: 100665746(IL22RA2)
TMU: 101350355
MDO: 100031558(IL22RA2)
SHR: 100928138
PCW: 110208927(IL22RA2)
OAA: 114805862(IL22RA2)
GGA: 770428(IL22RA2)
PCOC: 116240607(IL22RA2)
MGP: 100550792(IL22RA2)
CJO: 107311683(IL22RA2)
NMEL: 110396734(IL22RA2)
APLA: 101795963(IL22RA2)
ACYG: 106032393(IL22RA2)
TGU: 100225166(IL22RA2)
LSR: 110483318(IL22RA2)
SCAN: 103818468(IL22RA2)
PMOA: 120501374(IL22RA2)
GFR: 102040882(IL22RA2)
FAB: 101817593(IL22RA2)
PHI: 102103357(IL22RA2)
PMAJ: 107201345(IL22RA2)
CCAE: 111926796(IL22RA2)
CCW: 104689494(IL22RA2)
ETL: 114059496(IL22RA2)
FPG: 101910906(IL22RA2)
FCH: 102048241(IL22RA2)
CLV: 102097169(IL22RA2)
EGZ: 104131139(IL22RA2)
NNI: 104008887(IL22RA2)
ACUN: 113478557(IL22RA2)
PADL: 103912708(IL22RA2)
AAM: 106497939(IL22RA2)
NPD: 112954921(IL22RA2)
ASN: 102375227(IL22RA2)
AMJ: 102569947(IL22RA2)
CPOO: 109319323(IL22RA2)
GGN: 109304340(IL22RA2)
PSS: 102450521(IL22RA2)
CMY: 102936269(IL22RA2)
CPIC: 101944761(IL22RA2)
TST: 117874900(IL22RA2)
CABI: 116818793(IL22RA2)
DRE: 692307(il22ra2)
IPU: 108262818(Il22ra2)
PHYP: 113545711
AMEX: 103041691
EEE: 113571542 113575378(ifnlr1)
TRU: 101074849
LCO: 104931126
NCC: 104952614
CGOB: 115020022
ELY: 117248084(il22ra2)
SLUC: 116056322(il22ra2)
ECRA: 117960048(il22ra2)
PFLV: 114572444
GAT: 120820889(il22ra2)
MSAM: 119916822(il22ra2)
CUD: 121511532(il22ra2)
MZE: 101481349
ONL: 100690244
OAU: 116325772(il22ra2)
OLA: 101171885
OML: 112161553(il22ra2)
XMA: 102216928
XCO: 114138147
XHE: 116713294
PRET: 103476694
CVG: 107098121
CTUL: 119790565(il22ra2)
NFU: 107376094
KMR: 108243811(il22ra2)
ALIM: 106536532
AOCE: 111583945
CSEM: 103387072
POV: 109632154
LCF: 108897362
SDU: 111235335
SLAL: 111663746
XGL: 120796565(il22ra2)
HCQ: 109510188
BPEC: 110157093
MALB: 109962319
SASA: 106589254
OTW: 112224547
OMY: 101268955(il22ra2)
SALP: 111968020
SNH: 120029417(il22ra2)
ELS: 105021220
SFM: 108932841(il22ra2)
PKI: 111837610
AANG: 118217903 118221873(il22ra2)
LCM: 102350530
CMK: 103178354(il22ra2) 103180352(il10ra)
RTP: 109916185
 » show all
Reference
  Authors
Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S
  Title
Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity.
  Journal
J Immunol 166:7096-103 (2001)
DOI:10.4049/jimmunol.166.12.7096
  Sequence
[hsa:116379]
Reference
  Authors
Dumoutier L, Lejeune D, Hor S, Fickenscher H, Renauld JC
  Title
Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3.
  Journal
Biochem J 370:391-6 (2003)
DOI:10.1042/BJ20021935
LinkDB

KEGG   ORTHOLOGY: K05065
Entry
K05065                      KO                                     

Symbol
IL23R
Name
interleukin 23 receptor
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04659  Th17 cell differentiation
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H00286  Crohn disease
H01227  Inflammatory bowel disease (IBD)
H01466  Ulcerative colitis
H01476  Behcet disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05065  IL23R; interleukin 23 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05065  IL23R; interleukin 23 receptor
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K05065  IL23R; interleukin 23 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05065  IL23R; interleukin 23 receptor
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05065  IL23R; interleukin 23 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05065  IL23R; interleukin 23 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05065  IL23R; interleukin 23 receptor
Other DBs
GO: 0042019
Genes
HSA: 149233(IL23R)
PTR: 744045(IL23R)
PPS: 100980904(IL23R)
GGO: 101143774(IL23R)
PON: 100458963(IL23R)
NLE: 100582454(IL23R)
MCC: 700440(IL23R)
MCF: 102133210(IL23R)
CSAB: 103224658(IL23R)
CATY: 105595899(IL23R)
PANU: 101011937(IL23R)
RRO: 104657311(IL23R)
RBB: 108532958(IL23R)
TFN: 117092066(IL23R)
PTEH: 111541204(IL23R)
CJC: 100393072(IL23R)
SBQ: 101049947(IL23R)
MMUR: 105872848(IL23R)
MMU: 209590(Il23r)
MCAL: 110296994(Il23r)
MPAH: 110316831(Il23r)
RNO: 689932(Il23r)
MCOC: 116099026(Il23r)
MUN: 110539462(Il23r)
CGE: 100758310(Il23r)
PLEU: 114700907(Il23r)
NGI: 103743351(Il23r)
HGL: 101697943(Il23r)
CCAN: 109698315(Il23r)
OCU: 100350917(IL23R)
TUP: 102494268(IL23R)
CFA: 609732(IL23R)
VVP: 112907908(IL23R)
VLG: 121500246(IL23R)
AML: 100478419(IL23R)
UMR: 103663036(IL23R)
UAH: 113254554(IL23R)
ORO: 101377662(IL23R)
ELK: 111143244
MPUF: 101691534(IL23R)
EJU: 114208433(IL23R)
MLX: 118019294(IL23R)
FCA: 101087763(IL23R)
PYU: 121027279(IL23R)
PTG: 102953911(IL23R)
PPAD: 109266707(IL23R)
AJU: 106985193(IL23R)
HHV: 120232597(IL23R)
BTA: 614367(IL23R)
BOM: 102266368(IL23R)
BIU: 109556180(IL23R)
BBUB: 102400849(IL23R)
CHX: 102176576(IL23R)
OAS: 101103528(IL23R)
ODA: 120856566(IL23R)
CCAD: 122436849(IL23R)
SSC: 733613(IL23R)
CFR: 102523704(IL23R)
CBAI: 105075556(IL23R)
CDK: 105096623(IL23R)
BACU: 103020245(IL23R)
LVE: 103079131(IL23R)
OOR: 101283690(IL23R)
DLE: 111178441(IL23R)
PCAD: 102992121(IL23R)
ECB: 100053807(IL23R)
EPZ: 103559565(IL23R)
EAI: 106825072(IL23R)
MYB: 102239919(IL23R)
MYD: 102775548(IL23R)
MMYO: 118677052(IL23R)
MNA: 107533896(IL23R)
HAI: 109384961(IL23R)
DRO: 112309383(IL23R)
SHON: 118985593(IL23R)
AJM: 119063530(IL23R)
MMF: 118626700(IL23R)
PALE: 102885363(IL23R)
PGIG: 120583198(IL23R)
RAY: 107520572(IL23R)