KEGG   ORTHOLOGY: K05403
Entry
K05403                      KO                                     
Symbol
TIRAP
Name
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Pathway
map04064  NF-kappa B signaling pathway
map04620  Toll-like receptor signaling pathway
map04936  Alcoholic liver disease
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05133  Pertussis
map05152  Tuberculosis
map05161  Hepatitis B
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05417  Lipid and atherosclerosis
Disease
H00342  Tuberculosis
H00361  Malaria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09172 Infectious disease: viral
   05161 Hepatitis B
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05132 Salmonella infection
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05133 Pertussis
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05152 Tuberculosis
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Genes
HSA: 114609(TIRAP)
PTR: 451654(TIRAP)
PPS: 100975220(TIRAP)
GGO: 101139748(TIRAP)
PON: 100440980(TIRAP)
NLE: 100601986(TIRAP)
MCC: 714377(TIRAP)
MCF: 102121169
CSAB: 103248791(TIRAP)
CATY: 105582622(TIRAP)
PANU: 101025351(TIRAP)
TGE: 112606569(TIRAP)
RRO: 104653954(TIRAP)
RBB: 108542317(TIRAP)
TFN: 117080848(TIRAP)
PTEH: 111540313(TIRAP)
CJC: 100409771(TIRAP)
SBQ: 101038715(TIRAP)
CSYR: 103270561(TIRAP)
MMUR: 105875362(TIRAP)
OGA: 100956619(TIRAP)
MMU: 117149(Tirap)
MCAL: 110301823(Tirap)
MPAH: 110328152(Tirap)
RNO: 680127(Tirap)
MCOC: 116073400(Tirap)
MUN: 110555283(Tirap)
CGE: 100757985(Tirap)
PLEU: 114699775
NGI: 103735409(Tirap)
HGL: 101715320(Tirap)
CPOC: 100732763(Tirap)
CCAN: 109698469(Tirap)
DORD: 105980703(Tirap)
DSP: 122104201
NCAR: 124960254
OCU: 100338708(TIRAP)
OPI: 101536280
TUP: 102471752(TIRAP)
CFA: 609544(TIRAP)
VVP: 112920266(TIRAP)
VLG: 121501005
AML: 100470794(TIRAP)
UMR: 103660655(TIRAP)
UAH: 113259882(TIRAP)
UAR: 123792727
ELK: 111153868
LLV: 125080065
MPUF: 101670804(TIRAP)
ORO: 101375779(TIRAP)
EJU: 114222344(TIRAP)
ZCA: 113914776
MLX: 118013385(TIRAP)
FCA: 101088688(TIRAP)
PYU: 121035614
PBG: 122483129
PTG: 102970131(TIRAP)
PPAD: 109250350(TIRAP)
AJU: 106974926(TIRAP)
HHV: 120247108
BTA: 531079(TIRAP)
BOM: 102278504(TIRAP)
BIU: 109554591(TIRAP)
BBUB: 102404626
CHX: 102184789(TIRAP)
OAS: 101118490(TIRAP)
ODA: 120874445
CCAD: 122431228
SSC: 100514174(TIRAP)
CFR: 102524429(TIRAP)
CBAI: 105074212(TIRAP)
CDK: 105094263(TIRAP)
VPC: 102540249(TIRAP)
BACU: 103009631(TIRAP)
LVE: 103078296(TIRAP)
OOR: 101284698(TIRAP)
DLE: 111165480(TIRAP)
PCAD: 102979480(TIRAP)
PSIU: 116757769(TIRAP)
ECB: 100064503(TIRAP)
EPZ: 103549023(TIRAP)
MYB: 102260812(TIRAP)
MYD: 102767941 102774520(TIRAP)
MMYO: 118678493
MLF: 102432819(TIRAP)
MNA: 107530599(TIRAP)
PKL: 118725638
HAI: 109391405(TIRAP)
DRO: 112301793(TIRAP)
SHON: 118981479
AJM: 119041089
PDIC: 114509653
PHAS: 123832566
MMF: 118640256
RFQ: 117017715(TIRAP)
PALE: 102879591(TIRAP)
PGIG: 120610445
PVP: 105296799(TIRAP)
RAY: 107507804(TIRAP)
MJV: 108399058(TIRAP)
TOD: 119240831
SARA: 101552741(TIRAP)
LAV: 100660317(TIRAP)
TMU: 101355274
DNM: 101445854(TIRAP)
MDO: 100019477(TIRAP)
GAS: 123240638
SHR: 100913329(TIRAP)
PCW: 110218147(TIRAP)
OAA: 100084424
GGA: 419715(TIRAP)
PCOC: 116233049(TIRAP)
MGP: 100544782(TIRAP)
CJO: 107324201(TIRAP)
NMEL: 110387703(TIRAP)
APLA: 106017129(TIRAP)
ACYG: 106040636(TIRAP)
AFUL: 116497789(TIRAP)
TGU: 100220474(C28H19orf25) 105758827(TIRAP)
LSR: 110468189(TIRAP)
SCAN: 103822803(TIRAP)
PMOA: 120508343
OTC: 121340876
PRUF: 121360570
GFR: 102039379(TIRAP)
FAB: 101813451(TIRAP)
PHI: 102111777(TIRAP)
PMAJ: 107214435(TIRAP)
CCAE: 111939372(TIRAP)
CCW: 104692146
ETL: 114064610(TIRAP)
ZAB: 102060771(TIRAP)
FPG: 101910723(TIRAP)
FCH: 102047793(TIRAP)
CLV: 102099033(TIRAP)
EGZ: 104129233(TIRAP)
NNI: 104016675(TIRAP)
ACUN: 113488468(TIRAP)
TALA: 104369269
PADL: 103916420(TIRAP)
ACHC: 115344676
AROW: 112968910(TIRAP)
DNE: 112981566(TIRAP)
ASN: 106722059(TIRAP)
AMJ: 102563698(TIRAP) 102572807(CUNH19orf25)
CPOO: 109317987(TIRAP)
GGN: 109291836(TIRAP)
PSS: 102447956(TIRAP)
CMY: 102947697
CPIC: 101942636
TST: 117868684(TIRAP)
CABI: 116818798(TIRAP)
MRV: 120375449
ACS: 100567157(tirap)
PVT: 110088814(TIRAP)
SUND: 121934007
PBI: 103065850(TIRAP)
PMUR: 107298040(TIRAP)
TSR: 106548710(TIRAP)
PGUT: 117668199(TIRAP)
PMUA: 114585471(TIRAP)
ZVI: 118097192(TIRAP)
GJA: 107119895(TIRAP)
STOW: 125441715
XLA: 108696876 446390(tirap.L)
XTR: 100491693 733541(tirap)
DRE: 403148(tirap)
SANH: 107692532
PPRM: 120460010
MAMB: 125254607
AMEX: 111190370(tirap)
TRU: 100134854(tirap)
LCO: 104940498(tirap)
NCC: 104942069(tirap)
CGOB: 115018006(tirap)
ELY: 117260141
PLEP: 121943277
SLUC: 116043889
ECRA: 117941780(tirap)
PFLV: 114552630(tirap)
GAT: 120818667
PPUG: 119210660
MSAM: 119883428
CUD: 121518812
MZE: 101483841(tirap)
ONL: 100710220(tirap)
OAU: 116323300
OLA: 101157635(tirap)
OML: 112149705
XMA: 102237713(tirap)
XCO: 114161422(tirap)
XHE: 116737483(tirap)
PRET: 103474766(tirap)
PFOR: 103145357(tirap)
PLAI: 106957089(tirap)
PMEI: 106934185(tirap)
GAF: 122833117
CVG: 107083458(tirap)
CTUL: 119771830
GMU: 124884256
NFU: 107380709(tirap)
KMR: 108238172
ALIM: 106531962(tirap)
NWH: 119410850
AOCE: 111569196(tirap)
POV: 109634523(tirap)
SSEN: 122773468
HHIP: 117773144(tirap)
LCF: 108898789(tirap)
SDU: 111233420(tirap)
SLAL: 111665453(tirap)
XGL: 120792090
BPEC: 110162041(tirap)
SASA: 106581078
OTW: 112265616
OMY: 110507862(tirap)
OGO: 123992652
ONE: 115136661(tirap)
ELS: 105023818(tirap)
AANG: 118209597(tirap)
LOC: 102688338(tirap)
PSPA: 121309529
LCM: 102359565(TIRAP)
CMK: 103180241
RTP: 109924105(tirap)
BBEL: 109472909
GAE: 121378282
HRF: 124143726
HRJ: 124288105
 » show all
Reference
  Authors
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA
  Title
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
  Journal
Nature 413:78-83 (2001)
DOI:10.1038/35092578
  Sequence
[hsa:114609]
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