KEGG   ORTHOLOGY: K05828
Entry
K05828                      KO                                     
Symbol
lysZ, argB
Name
[amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
Pathway
map00220  Arginine biosynthesis
map00300  Lysine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Reaction
R09776  ATP:LysW-gamma-L-alpha-aminoadipate 6-phosphotransferase
R10930  ATP:LysW-L-glutamate 5-phosphotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05828  lysZ, argB; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
   00220 Arginine biosynthesis
    K05828  lysZ, argB; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.17  [amino-group carrier protein]-L-2-aminoadipate 6-kinase
     K05828  lysZ, argB; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
    2.7.2.19  [amino-group carrier protein]-L-glutamate 6-kinase
     K05828  lysZ, argB; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
Other DBs
COG: COG0548
Genes
MSD: MYSTI_01364
MFB: MFUL124B02_07575
MLAN: JY572_19540
CCX: COCOR_02070(argB)
PPAK: JY651_31955
AVM: JQX13_36420
GEK: kuro4_23320
SGR: SGR_3480
SFI: SFUL_3352
SFA: Sfla_0119
STRP: F750_6905
SRW: TUE45_06898(argB_2)
SLAU: SLA_3043
SALJ: SMD11_6706(lysZ)
SCYG: S1361_31460(argB2)
STPB: QR97_19345
SESP: BN6_56680
PLK: CIK06_18390(argB)
CAI: Caci_6305
RCA: Rcas_3466
CAU: Caur_1087
CAG: Cagg_1877
HAU: Haur_3308
ATM: ANT_12390(argB)
CAP: CLDAP_41070(argB)
TTR: Tter_0320
TRO: trd_1516(argB)
STI: Sthe_0218
DRA: DR_1420
DGE: Dgeo_0678
DEZ: DKM44_08260(argB)
DFC: DFI_07545
TRA: Trad_1399
TTH: TT_C1541
TTJ: TTHA1903(TTHA1903)
TSC: TSC_c01940(argB2)
TAQ: TO73_0100
MRB: Mrub_2721
TAI: Taci_0449
TLI: Tlie_1471
MRO: MROS_0162
CABY: Cabys_3151
PFU: PF1684
PFI: PFC_10185
PHO: PH1718(PH1718)
PAB: PAB0292(argB)
PYN: PNA2_0327
PYS: Py04_1634
TKO: TK0276
THS: TES1_0509
HHB: Hhub_3650(argB)
HALH: HTSR_0666(argB)
HHSR: HSR6_0692(argB)
HSU: HLASF_2139(argB)
HSF: HLASA_2173(argB)
HAHS: HSRCO_2861(argB)
SALI: L593_07895
HARA: AArcS_3063(argB)
HMA: rrnAC2676(argB2)
HHI: HAH_3081(argB2)
NPH: NP_5262A(argB)
NMO: Nmlp_1241(argB)
HUT: Huta_1500
HTI: HTIA_1541
HASV: SVXHr_0126(argB)
HABN: HBNXHr_0123(argB)
HMU: Hmuk_0774
HALL: LC1Hm_3290(argB)
HDS: HSR122_1703(argB)
HARC: HARCEL1_01515(argB)
HWA: HQ_3716A(argB)
HWC: Hqrw_4131(argB)
HVO: HVO_0044(argB)
HLN: SVXHx_0042(argb)
HME: HFX_0044(argB)
HLA: Hlac_2614
HDF: AArcSl_0041(argB)
HAAA: AArcCO_0043(argB)
HTU: Htur_0326
NMG: Nmag_1759(argB)
NAT: NJ7G_0261
PTO: PTO1471
FAI: FAD_0506(lysZ)
CDIV: CPM_0547
APE: APE_1461.1(lysZ)
ACJ: ACAM_0920(lysZ)
IHO: Igni_0621
IIS: EYM_06110
IPC: IPA_02000
IAG: Igag_1755
PABI: PABY_17880
PARE: PYJP_07900
STO: STK_01940(argB_lysZ)
SSO: SSO0156(argB)
SOL: Ssol_1134
SSOA: SULA_1170
SSOL: SULB_1171
SSOF: SULC_1169
SCAS: SACC_00690
SAI: Saci_0751
SID: M164_1989
SII: LD85_2244
SIH: SiH_1927
SIR: SiRe_1854
SIC: SiL_1836
MSE: Msed_0165
MEMJ: MJ1HA_0244
MCN: Mcup_1908
AHO: Ahos_0884
ACIH: HS5_22590
CSTY: KN1_18160
STEP: IC006_1903
PAI: PAE2882
PIS: Pisl_0277
PCL: Pcal_0372
PAS: Pars_0967
PYR: P186_1635
POG: Pogu_1379
TNE: Tneu_1836
CMA: Cmaq_1300
TTN: TTX_0121(lysZ_argB)
TUZ: TUZN_1286
VDI: Vdis_0202
VMO: VMUT_1540
KCR: Kcr_0810
NMR: Nmar_1290
NID: NPIRD3C_0834(argB)
NIN: NADRNF5_0666(argB)
NCL: C5F47_06950(argB)
NOX: C5F49_06960(argB)
NUE: C5F50_09715(argB)
NCT: NMSP_0398(argB)
NGA: Ngar_c29950(argB)
NVN: NVIE_1688(argB)
NEV: NTE_00735
TAA: NMY3_02223(argB)
NFN: NFRAN_2985(lysZ)
NCV: NCAV_1250(lysZ)
NBV: T478_1045(argB)
NDV: NDEV_1625(argB)
CCAI: NAS2_0268
BARB: AOA66_0021(argB)
 » show all
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
  Sequence
[tth:TT_C1541]
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0751]
LinkDB

KEGG   REACTION: R09776
Entry
R09776                      Reaction                               
Name
ATP:LysW-gamma-L-alpha-aminoadipate 6-phosphotransferase
Definition
LysW-gamma-L-alpha-aminoadipate + ATP <=> LysW-gamma-L-alpha-aminoadipyl 6-phosphate + ADP
Equation
Reaction class
RC00002  C00002_C00008
RC00043  C19886_C19887
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.17
     R09776  LysW-gamma-L-alpha-aminoadipate + ATP <=> LysW-gamma-L-alpha-aminoadipyl 6-phosphate + ADP
Orthology
K05828  [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
Other DBs
RHEA: 41947
LinkDB

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